Compounds > substance p
Page last updated: 2024-08-23

substance p and Itching

substance p has been researched along with Itching in 129 studies

Research

Studies (129)

TimeframeStudies, this research(%)All Research%
pre-19904 (3.10)18.7374
1990's10 (7.75)18.2507
2000's48 (37.21)29.6817
2010's62 (48.06)24.3611
2020's5 (3.88)2.80

Authors

AuthorsStudies
Bountouvas, A; Carstens, E; Domocos, D; Follansbee, T; Iodi Carstens, M; Nguyen, A; Nguyen, E; Ross, SE; Takanami, K; Velasquez, L1
Chen, H; Ge, W; Huang, Y; Jiang, J; Jin, Z; Kong, Y; Li, F; Li, L; Li, M; Liu, X; Zeng, X; Zhanmu, O1
Garces, JC; Ingrasci, G; Lipman, ZM; Loayza, E; Maldonado, C; Nattkemper, LA; Yosipovitch, G1
Bäumer, W; Fukuyama, T; Ganchingco, JRC; Yoder, JA1
Ahluwalia, A; Ingram, JR1
Metz, M1
Buscaglia, P; Fouyet, S; L'Herondelle, K; Le Gall-Ianotto, C; Le Garrec, R; Leschiera, R; Lewis, RJ; Michel, L; Mignen, O; Misery, L; Philippe, R; Pierre, O; Talagas, M1
Dang, NH; Hatano, R; Itoh, T; Kimura, U; Komiya, E; Morimoto, C; Ohnuma, K; Otsuka, H; Suga, Y; Takamori, K; Tominaga, M; Yamada, T; Yamazaki, H1
Azimi, E; Graham, TA; Lerner, EA; Reddy, VB1
Eirefelt, S; Hawro, T; Hoey, G; Koopmann, W; Maurer, M; Metz, M; Ohanyan, T; Schoepke, N1
Honda, T; Kabashima, K; Kitayama, N; Nakashima, C; Nonomura, Y; Otsuka, A; Usui, K; Wong, LS; Yamamoto, Y1
Bradley, M; Hall, MA; Heilborn, J; Holmberg, J; Holst, M; Killasli, H; Lönndahl, L; Nordlind, K; Theodorsson, E1
Choi, H; Chung, E; Hong, HS; Hwang, JS; Kim, DJ; Lim, S; Nam, S; Park, KS; Shin, MK; Son, Y; Won, Y1
Ahn, HJ; Choi, HW; Kim, KS; Shin, MK; Son, YS1
Andoh, T; Asakawa, Y; Kuraishi, Y1
Duvic, M; Huang, S; Lewis, DJ1
Carrion, AF; Levy, C; Rosen, JD1
Ständer, S; Yosipovitch, G1
Fayne, RA; Hashimoto, T; Kursewicz, CD; Nanda, S; Nattkemper, L; Shah, SM; Yokozeki, H; Yosipovitch, G1
Basbaum, AI; Eberhart, D; Meda, K; Rice, D; Solorzano, C; Urban, R; Wang, X; Yamanaka, H; Zhang, J1
Dwornicki, M; Gawlik, R; Grabiec, P; Grzeszczak, W; Kuźniewicz, R; Owczarek, A; Snit, M; Walaszczyk, M; Łącka-Gaździk, B1
Akiyama, T; Carstens, E; Carstens, MI; Takamori, K; Tominaga, M1
Funahashi, H; Ikeda, T; Matsushima, O; Naono-Nakayama, R; Nishimori, T; Sameshima, H; Takamiya, K1
Edvinsson, L; Wallengren, J1
Cho, SI; Choi, MG; Choi, YH; Kim, HO; Kwak, IS; Park, CW; Yang, YS1
Lotts, T; Ständer, S1
Choi, YH; Jang, YC; Kwak, IS; Lee, YK1
Ebihara, K; Funahashi, H; Ikeda, T; Ishida, Y; Koganemaru, G; Kuramashi, A; Naono-Nakayama, R; Nishimori, T1
Fisher, A; Ratti, E; Trower, MK; Upton, N1
Condjella, RM; Conley, O; Dahl, MV; Fryer, AD; Jacoby, DB; Jacoby, NW; Kloeber, JA; Lee, JJ; Lee, NA; Luo, H; Maizer, P; Mazzolini, A; Neely, JL; Ochkur, SI; Patel, YS; Protheroe, CA; Raish, RJ; Scott, GD; Vega, ML; Zellner, KR1
Andersen, HH; Kullander, K; Lagerström, MC; Rogoz, K1
Weber, HC1
Bettelini, L; Corsi, M; Costantini, VJ; Dünstl, G; Gerrard, P; Zonzini, L1
Arimura, A; Deguchi, M; Furue, Y; Haruna, T; Hikita, I; Ikeda, M; Imura, C; Imura, K; Morioka, Y; Shichijo, M; Soga, M; Yamamoto, M; Yamauchi, A; Yasui, K1
Ding, H; Hayashida, K; Kimura, M; Ko, MC; Mendenhall, V; Sukhtankar, DD; Suto, T1
Dijkstra, JF; Duraku, LS; Holstege, JC; Schüttenhelm, BN; Walbeehm, ET1
Luger, TA; Ständer, S2
Barry, DM; Chen, XJ; Chen, ZF; Li, H; Li, YQ; Liu, XT; Liu, XY; Munanairi, A; Shen, KF; Sun, YG; Wu, ZY; Yin, J1
Anthony, RM; Azimi, E; Lerner, EA; Pereira, PJS; Reddy, VB; Shade, KC; Talbot, S1
Agelopoulos, K; Loser, K; Lotts, T; Luger, TA; Phan, NQ; Schmaus, G; Ständer, S1
Azimi, E; Lerner, EA; Pereira, PJS; Reddy, VB; Talbot, S; Woolf, CJ1
Funahashi, H; Igawa, K; Ishida, Y; Matsuo, H; Miyahara, Y; Naono-Nakayama, R; Nishimori, T; Sakoda, S; Yamashita, Y1
Chau, NG; Kupper, TS; LeBoeuf, NR; Song, JS; Tawa, M1
Carr, MN; Koch, SN; Reiter, LV; Torres, SM1
Ko, MC; Naughton, NN1
Furue, M; Hosokawa, C; Takeuchi, S1
Oda, M; Sato, H; Suwa, E; Suzuki, M; Ueno, K; Yamaura, K1
Sato, S; Yoshizaki, A1
Chikumoto, T; Igeta, K; Inagaki, N; Itoh, T; Katoh, H; Kim, JF; Nagai, H; Nagao, M; Shiraishi, N; Tanaka, H1
Ikeda, T; Naono-Nakayama, R; Nishimori, T; Sunakawa, N1
Kawana, S; Yamaoka, J; Yilinuer, H1
Amatya, B; Nordlind, K; Wahlgren, CF1
Carstens, EE; Carstens, MI; Jinks, SL; Simons, CT1
Böhm, M; Capellino, S; Haas, S; Luger, TA; Phan, NQ; Ständer, S; Straub, RH1
Andoh, T; Hattori, M; Konno, M; Kuraishi, Y; Lee, JB; Zhang, Q1
Blass, GR; Lewin, GR; Park, TJ; Smith, ES1
Namiki, T; Suzuki, M; Ueno, K; Yamaura, K1
Bae, BG; Lee, KH; Noh, JY; Oh, SH; Park, CO; Park, IH; Wu, WH1
Buhren, BA; Gerber, PA; Homey, B1
Bito, T; Fukamachi, S; Kabashima, K; Kobayashi, M; Kuroda, E; Mori, T; Nakamura, M; Sakabe, J; Shiraishi, N; Tokura, Y1
Carlson Scholz, JA; Deng, Y; Franklin, R; Smith, PC; Williams-Fritze, MJ; Wilson, SR; Zeiss, C1
Metz, M; Raap, U; Ständer, S1
Akasaka, Y; Hatta, A; Inoue, H; Tsukahara, M; Yoshida, T1
Amiri, M; Beiraghdar, F; Davoudi, SM; Hoseininejad, SL; Kolivand, M; Panahi, Y; Sahebkar, A1
Ferguson, MWJ; Henderson, J; Terenghi, G1
Silberstein, M1
Cynkier, A; Danilewicz, M; Erkiert-Polguj, A; Stasikowska-Kanicka, O; Sysa-Jędrzejowska, A; Wągrowska-Danilewicz, M; Waszczykowska, E; Zebrowska, A1
Davoudi, SM; Panahi, Y; Ranjbar, R; Sahebkar, A; Taherzadeh, ES1
Abd El-Latif, MI; Izumi, M; Katayama, I; Matsui, S; Murota, H; Nishioka, M; Sano, S; Tani, M; Terao, M1
Honda, T; Mochizuki, H; Momen, S; Nakao, K; Okano, K; Sakakibara, S; Tanaka, T; Togashi, Y; Umeuchi, H1
Hawro, T; Lesiak, A; Narbutt, J; Olejniczak, I; Sobolewska-Sztychny, D; Sysa-Jedrzejowska, A; Słowik-Kwiatkowska, I1
Akiyama, T; Blansit, K; Carstens, E; Carstens, MI; Davoodi, A; Horwitz, A; Nagamine, M; Tominaga, M1
Andoh, T; Kuraishi, Y4
Carstens, E; Cuellar, JM; Jinks, SL; Simons, CT1
Al-Akeel, A; Andoh, T; Honma, Y; Kawaharada, S; Kuraishi, Y; Nojima, H1
Hossen, MA; Kamei, C; Kayasuga, R; Sugimoto, Y1
Honda, T; Nagase, H; Nakao, K; Okano, K; Tanaka, T; Togashi, Y; Umeuchi, H1
Al-Akeel, A; Andoh, T; Kuraishi, Y; Nojima, H; Tsujii, K1
Artuc, M; Brzoska, T; Buddenkotte, J; Henz, BM; Lippert, U; Luger, TA; Metze, D; Moormann, C; Schumacher, M; Shpacovitch, V; Ständer, S; Steinhoff, M1
English, KB; Johansson, O; Saffle, JR; Tuckett, RP; Ward, RS1
Hayashi, T; Jung, B; Konomi, A; Ohmura, T; Satoh, H; Satoh, Y1
Ebata, T1
Ikeda, M; Kodama, H; Ohtsu, H; Seike, M; Terui, T1
Ben Smail, D; Bussel, B; Denys, P; Hugeron, C1
Kim, DH; Shin, YW1
Fujii, Y; Hossen, MA; Inoue, T; Kamei, C; Shinmei, Y; Watanabe, T1
Andoh, T2
Hosogi, M; Ikoma, A; Miyachi, Y; Schmelz, M1
Brain, SD; Costa, SK; Gilmore, D; Hyslop, S; Starr, A1
Hamada, R; Ikeda, M; Kamijima, R; Kodama, H; Ohtsu, H; Seike, M1
Bady, P; Baumann, T; Bigliardi, PL; Bigliardi-Qi, M; Gaveriaux-Ruff, C; Kieffer, BL; Pfaltz, K; Rufli, T1
Di, ZH; Kawana, S; Sun, W; Yamaoka, J2
Lonne-Rahm, S; Nordlind, K; Remröd, C1
Akiyama, H; Amano, H; Ishikawa, O; Negishi, I1
Bíró, T; Dobrosi, N; Géczy, T; Marincsák, R; Paus, R; Tóth, BI1
Aki, T; Hashimoto, K; Hide, M; Kawamoto, S; Onishi, N; Ono, K; Santo, H; Shigeta, S; Suzuki, H1
Kawana, S; Yamaoka, J2
Hon, KL; Lam, MC; Leung, TF; Ng, PC; Wong, KY1
Baran, E; Salomon, J1
Andoh, T; Kosaka, M; Kuraishi, Y; Lee, JB; Nakano, T; Tayama, M1
Fjellner, B; Hägermark, O1
Hartschuh, W; Reinecke, M; Weihe, E1
Ekblom, A; Lundeberg, T; Wahlgren, CF1
Lotti, T; Teofoli, P; Tsampau, D1
Hayashi, K; Kuraishi, Y; Nagasawa, T; Satoh, M1
Berberian, B; Dodd, WA; Ellis, CN; Jarratt, MT; Katz, HI; Krueger, G; Prawer, S; Rex, IH; Sulica, VI; Wolf, JE1
Handwerker, HO; Heyer, G; Schmitz, J; Ulmer, FJ1
Cremer, B; Czarnetzki, BM; Dippel, E; Heimann, A1
Boehncke, WH; Gall, H; Kaufmann, R; Schultz, KD1
Cho, YL; Huang, TP; Liu, HN; Tarng, DC1
Andoh, T; Kuraishi, Y; Nagasawa, T; Satoh, M1
Kakihara, Y; Komatsu, K; Kuraishi, Y; Tohda, C1
Kaneko, M; Kawakita, T; Kuraishi, Y; Maekawa, T; Miyamoto, T; Nishikawa, Y; Nojima, H; Yamaguchi, T1
Luger, T; Metze, D; Ständer, S1
Marsella, R; Nicklin, CF1
Ando, N; Endoh, T; Honda, T; Kamei, J; Kawamura, K; Nagase, H; Okano, K; Tanaka, T; Togashi, Y; Umeuchi, H; Utsumi, J; Yoshizawa, Y1
Andoh, T; Katsube, N; Kuraishi, Y; Maruyama, M1
Culhaci, N; Dikicioğlu, E; Karaman, G; Savk, E; Sendur, N1
Marsella, R; Melloy, C; Nicklin, CF1
Fujita, Y; Kaku, H; Kawakubo, H; Naka, F; Nakano, K; Nishikawa, K; Suehiro, S; Yago, H1
Mygind, N; Schaffalitzky de Muckadell, OB; Tønnesen, P1
Bernstein, JE1

Reviews

14 review(s) available for substance p and Itching

ArticleYear
Inflammatory cytokines and peripheral mediators in the pathophysiology of pruritus in cutaneous T-cell lymphoma.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:10

    Topics: Analgesics, Opioid; Histamine; Humans; Interleukins; Lymphoma, T-Cell, Cutaneous; Nerve Growth Factor; Nicotinamide Phosphoribosyltransferase; Pruritus; Substance P

2018
Understanding and Treating Pruritus in Primary Biliary Cholangitis.
    Clinics in liver disease, 2018, Volume: 22, Issue:3

    Topics: Anion Exchange Resins; Bile Acids and Salts; Cholestyramine Resin; Drainage; Filtration; Humans; Liver Cirrhosis, Biliary; Lysophospholipids; Narcotic Antagonists; Opioid Peptides; Phosphoric Diester Hydrolases; Plasmapheresis; Pruritus; Receptors, Opioid; Rifampin; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Substance P

2018
Substance P and neurokinin 1 receptor are new targets for the treatment of chronic pruritus.
    The British journal of dermatology, 2019, Volume: 181, Issue:5

    Topics: Animals; Chronic Disease; Clinical Trials, Phase II as Topic; Disease Models, Animal; Humans; Molecular Targeted Therapy; Neurokinin-1 Receptor Antagonists; Pruritus; Quality of Life; Receptors, Neurokinin-1; Severity of Illness Index; Signal Transduction; Skin; Substance P; Treatment Outcome

2019
Research in practice: substance P antagonism in chronic pruritus.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2014, Volume: 12, Issue:7

    Topics: Anti-Inflammatory Agents; Chronic Disease; Cytokines; Dermatologic Agents; Evidence-Based Medicine; Humans; Models, Immunological; Pruritus; Skin; Substance P

2014
Gastrointestinal peptides and itch sensation.
    Current opinion in endocrinology, diabetes, and obesity, 2015, Volume: 22, Issue:1

    Topics: Gastrin-Releasing Peptide; Humans; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Pruritus; Signal Transduction; Spinal Cord; Substance P

2015
NK-1 Antagonists and Itch.
    Handbook of experimental pharmacology, 2015, Volume: 226

    Topics: Animals; Aprepitant; Humans; Morpholines; Pruritus; Receptors, Neurokinin-1; Substance P

2015
Aprepitant for refractory cutaneous T-cell lymphoma-associated pruritus: 4 cases and a review of the literature.
    BMC cancer, 2017, 03-16, Volume: 17, Issue:1

    Topics: Adult; Aged; Aprepitant; Female; Humans; Lymphoma, T-Cell, Cutaneous; Male; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Protein Binding; Pruritus; Substance P

2017
[Expression of the histamine H4 receptor in human tissues and its clinical role].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 135, Issue:6

    Topics: Animals; Arthritis, Rheumatoid; Cell Differentiation; Histamine Antagonists; Humans; Keratinocytes; Pruritus; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Skin; Substance P; Synovial Membrane

2010
Pathophysiology of itch and new treatments.
    Current opinion in allergy and clinical immunology, 2011, Volume: 11, Issue:5

    Topics: Anti-Allergic Agents; Brain-Derived Neurotrophic Factor; Histamine; Humans; Interleukins; Keratinocytes; Mast Cells; Nerve Growth Factor; Neurokinin-1 Receptor Antagonists; Neurons; Pruritus; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Skin; Substance P

2011
[Generalized pruritus in hemodialysis patients].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 6

    Topics: Cytokines; Histamine Release; Humans; Kidney Failure, Chronic; Mast Cells; Opioid Peptides; Pruritus; Renal Dialysis; Substance P

2004
[Importance of epidermal keratinocytes in itching].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2006, Volume: 126, Issue:6

    Topics: Animals; Disease Models, Animal; Drug Design; Epidermal Cells; Histamine Release; Humans; Keratinocytes; Leukotriene B4; Mast Cells; Mice; Nitric Oxide; Pruritus; Receptor, PAR-2; Substance P

2006
TRP channels as novel players in the pathogenesis and therapy of itch.
    Biochimica et biophysica acta, 2007, Volume: 1772, Issue:8

    Topics: Animals; Cannabinoids; Capsaicin; Central Nervous System; Histamine; Humans; Inflammation Mediators; Nerve Growth Factors; Neurons; Neurons, Afferent; Neuropeptides; Pain; Pruritus; Spinal Cord; Substance P; Temperature; Transient Receptor Potential Channels; TRPV Cation Channels

2007
[Mechanisms of cutaneous itch: new itch mediators and enhancement factors produced by keratinocytes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2008, Volume: 131, Issue:5

    Topics: Animals; Autocrine Communication; Drug Design; Free Radicals; Histamine; Humans; Hydrogen Peroxide; Immunoglobulin E; Keratinocytes; Leukotriene B4; Mast Cells; Nitric Oxide; Pruritus; Receptors, IgG; Substance P; Thromboxane A2

2008
Capsaicin in dermatologic disease.
    Seminars in dermatology, 1988, Volume: 7, Issue:4

    Topics: Capsaicin; Humans; Middle Aged; Neuralgia; Pruritus; Skin Diseases; Substance P

1988

Trials

10 trial(s) available for substance p and Itching

ArticleYear
Role of Substance P and Its Receptor Neurokinin 1 in Chronic Prurigo: A Randomized, Proof-of-Concept, Controlled Trial with Topical Aprepitant.
    Acta dermato-venereologica, 2018, Jan-12, Volume: 98, Issue:1

    Topics: Administration, Cutaneous; Aged; Aprepitant; Case-Control Studies; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Proof of Concept Study; Prospective Studies; Prurigo; Pruritus; Receptors, Neurokinin-1; Severity of Illness Index; Substance P; Visual Analog Scale

2018
Substance P Antagonist Aprepitant Shows no Additive Effect Compared with Standardized Topical Treatment Alone in Patients with Atopic Dermatitis.
    Acta dermato-venereologica, 2018, Mar-13, Volume: 98, Issue:3

    Topics: Administration, Cutaneous; Adult; Antipruritics; Aprepitant; Dermatitis, Atopic; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Pruritus; Severity of Illness Index; Skin; Substance P; Sweden; Time Factors; Treatment Outcome; Young Adult

2018
Severity scores, itch scores and plasma substance P levels in atopic dermatitis treated with standard topical therapy with oral olopatadine hydrochloride.
    The Journal of dermatology, 2009, Volume: 36, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adult; Dermatitis, Atopic; Dibenzoxepins; Drug Synergism; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Olopatadine Hydrochloride; Pruritus; Substance P; Young Adult

2009
Responses to intradermal injections of substance P in psoriasis patients with pruritus.
    Skin pharmacology and physiology, 2010, Volume: 23, Issue:3

    Topics: Adult; Area Under Curve; Case-Control Studies; Double-Blind Method; Female; Histamine; Humans; Injections, Intradermal; Male; Middle Aged; Pruritus; Psoriasis; Severity of Illness Index; Substance P; Time Factors

2010
Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial.
    The British journal of nutrition, 2012, Volume: 108, Issue:7

    Topics: Adult; Antioxidants; Antipruritics; Chemical Warfare Agents; Chronic Disease; Curcumin; Dietary Supplements; Double-Blind Method; Humans; Iran; Irritants; Male; Middle Aged; Mustard Gas; Oxidoreductases; Pruritus; Quality of Life; Severity of Illness Index; Substance P; Surveys and Questionnaires; Veterans

2012
Treatment of aquagenic pruritus with topical capsaicin cream.
    Journal of the American Academy of Dermatology, 1994, Volume: 30, Issue:2 Pt 1

    Topics: Administration, Topical; Capsaicin; Double-Blind Method; Female; Fluorescent Antibody Technique; Humans; Male; Nerve Fibers; Neuropeptides; Pruritus; Skin; Substance P; Water

1994
A double-blind evaluation of topical capsaicin in pruritic psoriasis.
    Journal of the American Academy of Dermatology, 1993, Volume: 29, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Aged; Capsaicin; Double-Blind Method; Female; Humans; Male; Middle Aged; Pruritus; Psoriasis; Substance P

1993
Uremic pruritus: roles of parathyroid hormone and substance P.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:4

    Topics: Calcium; Capsaicin; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Parathyroid Hormone; Phosphates; Pruritus; Renal Dialysis; Substance P

1997
Treatment of prurigo nodularis with topical capsaicin.
    Journal of the American Academy of Dermatology, 2001, Volume: 44, Issue:3

    Topics: Administration, Topical; Adult; Aged; Biopsy; Capsaicin; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Prurigo; Pruritus; Substance P; Treatment Outcome

2001
The effects of capsaicin topical therapy in dogs with atopic dermatitis: a randomized, double-blinded, placebo-controlled, cross-over clinical trial.
    Veterinary dermatology, 2002, Volume: 13, Issue:3

    Topics: Administration, Cutaneous; Animals; Capsaicin; Cross-Over Studies; Dermatitis, Atopic; Dog Diseases; Dogs; Double-Blind Method; Female; Male; Pruritus; Substance P; Treatment Outcome

2002

Other Studies

105 other study(ies) available for substance p and Itching

ArticleYear
Inhibition of itch by neurokinin 1 receptor (Tacr1) -expressing ON cells in the rostral ventromedial medulla in mice.
    eLife, 2022, 08-16, Volume: 11

    Topics: Animals; Medulla Oblongata; Mice; Neurons; Pruritus; Receptors, Neurokinin-1; Substance P

2022
Role of Type I Cannabinoid Receptor in Sensory Neurons in Psoriasiform Skin Inflammation and Pruritus.
    The Journal of investigative dermatology, 2023, Volume: 143, Issue:5

    Topics: Animals; Eczema; Imiquimod; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Pruritus; Psoriasis; Receptors, Cannabinoid; Sensory Receptor Cells; Substance P

2023
Neuroimmune Mediators of Pruritus in Hispanic Scalp Psoriatic Itch.
    Acta dermato-venereologica, 2023, Mar-23, Volume: 103

    Topics: Hispanic or Latino; Humans; Pruritus; Psoriasis; Scalp; Substance P

2023
Calcium imaging of primary canine sensory neurons: Small-diameter neurons responsive to pruritogens and algogens.
    Brain and behavior, 2019, Volume: 9, Issue:12

    Topics: Animals; Cadaver; Calcium Radioisotopes; Capsaicin; Cattle; Cells, Cultured; Chloroquine; Dogs; Ganglia, Spinal; Histamine; Humans; Laminectomy; Molecular Imaging; Neurotransmitter Agents; Pain; Peptide Fragments; Pruritus; Radiopharmaceuticals; Sensory Receptor Cells; Serotonin; Serotonin Receptor Agonists; Substance P

2019
The pharmacology of itch.
    British journal of pharmacology, 2019, Volume: 176, Issue:23

    Topics: Antipruritics; Humans; Pruritus; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Receptors, Neurokinin-1; Substance P

2019
Are we facing a change in the treatment of chronic pruritus?
    The British journal of dermatology, 2019, Volume: 181, Issue:5

    Topics: Chronic Disease; Humans; Pruritus; Receptors, Neurokinin-1; Substance P

2019
PAR2, Keratinocytes, and Cathepsin S Mediate the Sensory Effects of Ciguatoxins Responsible for Ciguatera Poisoning.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:3

    Topics: Animals; Calcium; Cathepsins; Ciguatera Poisoning; Ciguatoxins; Coculture Techniques; Cytosol; Disease Models, Animal; Epidermis; Humans; Intravital Microscopy; Keratinocytes; Paresthesia; Primary Cell Culture; Pruritus; Rats; Receptor, PAR-2; Sensory Receptor Cells; Single-Cell Analysis; Substance P

2021
A possible role for CD26/DPPIV enzyme activity in the regulation of psoriatic pruritus.
    Journal of dermatological science, 2017, Volume: 86, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antipruritics; Behavior, Animal; Biomarkers; Case-Control Studies; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Female; Genetic Predisposition to Disease; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Phenotype; Pruritus; Psoriasis; Substance P; Time Factors; Up-Regulation; Young Adult

2017
A single amino acid in MRGPRX2 necessary for binding and activation by pruritogens.
    The Journal of allergy and clinical immunology, 2017, Volume: 140, Issue:6

    Topics: Arginine; Glutamic Acid; HEK293 Cells; HeLa Cells; Humans; Models, Molecular; Nerve Tissue Proteins; p-Methoxy-N-methylphenethylamine; Pruritus; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance P

2017
TRPA1 channel participates in tacrolimus-induced pruritus in a chronic contact hypersensitivity murine model.
    Journal of dermatological science, 2018, Volume: 89, Issue:2

    Topics: Administration, Cutaneous; Animals; Aprepitant; Behavior, Animal; Calcineurin Inhibitors; Dermatitis, Contact; Disease Models, Animal; Filaggrin Proteins; Ganglia, Spinal; Humans; Intermediate Filament Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Ointments; Oxazolone; Oximes; Pruritus; Skin; Substance P; Tacrolimus; TRPA1 Cation Channel

2018
Substance P restores normal skin architecture and reduces epidermal infiltration of sensory nerve fiber in TNCB-induced atopic dermatitis-like lesions in NC/Nga mice.
    Journal of dermatological science, 2018, Volume: 89, Issue:3

    Topics: Animals; Body Water; Cells, Cultured; Dermatitis, Atopic; Epidermis; Filaggrin Proteins; Male; Mice; Nerve Fibers; Nerve Growth Factor; Picryl Chloride; Pruritus; Semaphorin-3A; Skin; Substance P

2018
Pretreatment with substance P alleviates irritation due to sodium lauryl sulphate exposure by maintaining E-cadherin expression on human keratinocytes.
    Clinical and experimental dermatology, 2018, Volume: 43, Issue:3

    Topics: Cadherins; Cell Adhesion; Cell Survival; Dermatitis, Irritant; Detergents; Humans; Keratinocytes; Neurotransmitter Agents; Pruritus; Sodium Dodecyl Sulfate; Substance P

2018
Non-myelinated C-fibers, but not myelinated A-fibers, elongate into the epidermis in dry skin with itch.
    Neuroscience letters, 2018, 04-13, Volume: 672

    Topics: Animals; Calcitonin Gene-Related Peptide; Epidermis; Male; Mice; Mice, Inbred ICR; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Pruritus; Skin; Substance P

2018
Pathophysiologic mechanisms of itch in bullous pemphigoid.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Basophils; Cell Adhesion Molecules; Chronic Disease; Cytokines; Eosinophils; Female; Fluorescent Antibody Technique; Humans; Interleukin-13; Male; Middle Aged; Oncostatin M Receptor beta Subunit; Pemphigoid, Bullous; Pruritus; Receptors, Interleukin; Receptors, Neurokinin-1; Severity of Illness Index; Skin; Substance P; Th2 Cells

2020
Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch.
    Neuron, 2013, Apr-24, Volume: 78, Issue:2

    Topics: Animals; Cell Death; Cognition Disorders; Disease Models, Animal; Glutamate Decarboxylase; Green Fluorescent Proteins; Hyperalgesia; Interneurons; Lectins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oncogene Proteins v-fos; Pain; Pain Threshold; Phosphopyruvate Hydratase; Pruritus; Reaction Time; Receptors, Steroid; Receptors, Thyroid Hormone; Spinal Nerve Roots; Substance P

2013
Substance P and intensity of pruritus in hemodialysis and peritoneal dialysis patients.
    Medical science monitor : international medical journal of experimental and clinical research, 2013, Sep-02, Volume: 19

    Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Calcium; Enzyme-Linked Immunosorbent Assay; Female; Ferritins; Humans; Iron; Kidney Failure, Chronic; Male; Middle Aged; Nephelometry and Turbidimetry; Parathyroid Hormone; Peritoneal Dialysis; Phosphorus; Pruritus; Renal Dialysis; Statistics, Nonparametric; Substance P

2013
Roles of glutamate, substance P, and gastrin-releasing peptide as spinal neurotransmitters of histaminergic and nonhistaminergic itch.
    Pain, 2014, Volume: 155, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Antirheumatic Agents; Bombesin; Chloroquine; Drug Combinations; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Gastrin-Releasing Peptide; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Piperidines; Pruritus; Substance P; Vesicular Glutamate Transport Protein 2

2014
An amino-terminal fragment of hemokinin-1 has an inhibitory effect on pruritic processing in rats.
    Neuroscience, 2014, Feb-14, Volume: 259

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Drug Administration Routes; Injections, Spinal; Male; Pain Measurement; Peptide Fragments; Proto-Oncogene Proteins c-fos; Pruritus; Rats; Rats, Sprague-Dawley; Substance P; Tachykinins; Time Factors

2014
Topical non-peptide antagonists of sensory neurotransmitters substance P and CGRP do not modify patch test and prick test reactions: a vehicle-controlled, double-blind pilot study.
    Archives of dermatological research, 2014, Volume: 306, Issue:5

    Topics: Adult; Aged; Antipruritics; Aprepitant; Azepines; Calcitonin Gene-Related Peptide; Dermatitis, Contact; Double-Blind Method; Female; Humans; Hypersensitivity, Delayed; Imidazoles; Male; Middle Aged; Morpholines; Nickel; Permeability; Pilot Projects; Pruritus; Skin; Skin Physiological Phenomena; Skin Tests; Substance P; Urticaria; Vasoconstriction; Water Loss, Insensible; Young Adult

2014
Increased expression of three types of transient receptor potential channels (TRPA1, TRPV4 and TRPV3) in burn scars with post-burn pruritus.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:1

    Topics: Adolescent; Adult; Biopsy; Burns; Calcitonin Gene-Related Peptide; Calcium Channels; Child; Cicatrix; Epidermis; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nerve Tissue Proteins; Pruritus; Real-Time Polymerase Chain Reaction; RNA, Messenger; Substance P; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Young Adult

2015
Immunohistochemical analysis of neuropeptides (protein gene product 9.5, substance P and calcitonin gene-related peptide) in hypertrophic burn scar with pain and itching.
    Burns : journal of the International Society for Burn Injuries, 2014, Volume: 40, Issue:8

    Topics: Adult; Burns; Calcitonin Gene-Related Peptide; Case-Control Studies; Cicatrix, Hypertrophic; Female; Humans; Immunohistochemistry; Male; Middle Aged; Pain; Pruritus; Skin; Substance P; Ubiquitin Thiolesterase

2014
Hemokinin-1 mediates pruriceptive processing in the rat spinal cord.
    Neuroscience, 2014, Sep-26, Volume: 277

    Topics: Animals; Disease Models, Animal; Formaldehyde; Histamine; Immunohistochemistry; Male; Nociception; Pain; Proto-Oncogene Proteins c-fos; Pruritus; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Substance P; Tachykinins

2014
Neurokinin-1 receptor antagonist orvepitant is an effective inhibitor of itch-associated response in a Mongolian gerbil model of scratching behaviour.
    Experimental dermatology, 2014, Volume: 23, Issue:11

    Topics: Administration, Oral; Animals; Antipruritics; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dose-Response Relationship, Drug; Gerbillinae; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pruritus; Substance P

2014
Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice.
    The Journal of allergy and clinical immunology, 2015, Volume: 135, Issue:2

    Topics: Allergens; Animals; Cell Degranulation; Collagen; Dinitrofluorobenzene; Disease Models, Animal; Eosinophilia; Eosinophils; Fibrosis; Inflammation; Mice; Phthalic Anhydrides; Pruritus; Skin; Substance P

2015
Multimodal use of calcitonin gene-related peptide and substance P in itch and acute pain uncovered by the elimination of vesicular glutamate transporter 2 from transient receptor potential cation channel subfamily V member 1 neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Oct-15, Volume: 34, Issue:42

    Topics: Acute Pain; Animals; Calcitonin Gene-Related Peptide; Female; Male; Mice; Mice, Transgenic; Neurons; Pain Measurement; Pruritus; Substance P; TRPV Cation Channels; Vesicular Glutamate Transport Protein 2

2014
The NK1 receptor antagonist aprepitant attenuates NK1 agonist-induced scratching behaviour in the gerbil after intra-dermal, topical or oral administration.
    Experimental dermatology, 2015, Volume: 24, Issue:4

    Topics: Administration, Oral; Administration, Topical; Animals; Antipruritics; Aprepitant; Disease Models, Animal; Drug Evaluation, Preclinical; Gerbillinae; Humans; Injections, Intradermal; Morpholines; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Pruritus; Receptors, Neurokinin-1; Substance P

2015
S-777469, a novel cannabinoid type 2 receptor agonist, suppresses itch-associated scratching behavior in rodents through inhibition of itch signal transmission.
    Pharmacology, 2015, Volume: 95, Issue:1-2

    Topics: Animals; Behavior, Animal; Female; Ganglia, Spinal; Histamine; Mice, Inbred ICR; Neurons; p-Methoxy-N-methylphenethylamine; Pruritus; Pyridones; Rats, Inbred F344; Receptor, Cannabinoid, CB2; Serotonin; Signal Transduction; Substance P

2015
Supraspinal actions of nociceptin/orphanin FQ, morphine and substance P in regulating pain and itch in non-human primates.
    British journal of pharmacology, 2015, Volume: 172, Issue:13

    Topics: Animals; Behavior, Animal; Catheterization; Cisterna Magna; Female; Injections, Spinal; Lumbosacral Region; Macaca mulatta; Male; Morphine; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pain; Pruritus; Receptors, Opioid; Substance P

2015
Differential Changes in the Peptidergic and the Non-Peptidergic Skin Innervation in Rat Models for Inflammation, Dry Skin Itch, and Dermatitis.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:8

    Topics: Acetone; Animals; Biopsy; Calcitonin Gene-Related Peptide; Dermatitis; Dinitrochlorobenzene; Disease Models, Animal; Freund's Adjuvant; Inflammation; Male; Nerve Fibers; Pruritus; Rats; Rats, Wistar; Receptors, Purinergic P2X3; Skin; Substance P

2015
Critical evaluation of the expression of gastrin-releasing peptide in dorsal root ganglia and spinal cord.
    Molecular pain, 2016, Volume: 12

    Topics: Amino Acid Sequence; Animals; Antibody Specificity; Cell Count; Cells, Cultured; Chronic Disease; Ganglia, Spinal; Gastrin-Releasing Peptide; Gene Deletion; Gene Expression Regulation; Male; Mice, Inbred C57BL; Mice, Knockout; Posterior Horn Cells; Pruritus; Receptors, Bombesin; RNA, Messenger; Spinal Cord; Substance P

2016
Dual action of neurokinin-1 antagonists on Mas-related GPCRs.
    JCI insight, 2016, Oct-06, Volume: 1, Issue:16

    Topics: Animals; Cell Degranulation; Cell Line; HEK293 Cells; HeLa Cells; Humans; Mast Cells; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Pruritus; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance P

2016
Dihydroavenanthramide D inhibits mast cell degranulation and exhibits anti-inflammatory effects through the activation of neurokinin-1 receptor.
    Experimental dermatology, 2017, Volume: 26, Issue:8

    Topics: Animals; Calcium Signaling; Cell Line; Chronic Disease; Drug Evaluation, Preclinical; Humans; Mast Cells; ortho-Aminobenzoates; Pruritus; Rats; Receptors, Neurokinin-1; Substance P

2017
Substance P activates Mas-related G protein-coupled receptors to induce itch.
    The Journal of allergy and clinical immunology, 2017, Volume: 140, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Capsaicin; Cells, Cultured; Female; Ganglia, Spinal; Humans; Male; Mice, Transgenic; Middle Aged; Pruritus; Receptors, G-Protein-Coupled; Receptors, Neurokinin-1; Sensory Receptor Cells; Substance P; Young Adult

2017
Distribution of hemokinin-1 in the rat trigeminal ganglion and trigeminal sensory nuclear complex.
    Archives of oral biology, 2017, Volume: 79

    Topics: Amino Acid Sequence; Animals; Antigens, Nuclear; Brain Stem; Guinea Pigs; Immunohistochemistry; Male; Nerve Tissue Proteins; Neurons; Pain; Pruritus; Rabbits; Rats; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; Substance P; Tachykinins; Trigeminal Caudal Nucleus; Trigeminal Ganglion

2017
Investigation of the pruritogenic effects of histamine, serotonin, tryptase, substance P and interleukin-2 in healthy dogs.
    Veterinary dermatology, 2009, Volume: 20, Issue:2

    Topics: Analgesics, Non-Narcotic; Animals; Dog Diseases; Dogs; Female; Histamine; Histamine Agonists; Interleukin-2; Neurotransmitter Agents; Pruritus; Serotonin; Serotonin Agents; Substance P; Tryptases

2009
Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.
    The journal of pain, 2009, Volume: 10, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Hyperalgesia; Injections, Spinal; Macaca mulatta; Male; Morphine; Nociceptin; Opioid Peptides; Pain Measurement; Pruritus; Receptors, Opioid; Substance P

2009
Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist.
    The Journal of toxicological sciences, 2009, Volume: 34, Issue:4

    Topics: Animals; Disease Models, Animal; Epidermis; Histamine; Histamine Antagonists; Humans; Indoles; Keratinocytes; Male; Mice; Mice, Inbred ICR; Piperazines; Pruritus; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Substance P

2009
Olopatadine hydrochloride inhibits scratching behavior induced by a proteinase-activated receptor 2 agonist in mice.
    Journal of dermatological science, 2009, Volume: 56, Issue:2

    Topics: Animals; Antipruritics; Behavior, Animal; Dibenzoxepins; Disease Models, Animal; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Oligopeptides; Olopatadine Hydrochloride; Protein Precursors; Pruritus; Receptor, PAR-2; RNA, Messenger; Substance P; Tachykinins; Time Factors

2009
Depletion of substance P, a mechanism for inhibition of mouse scratching behavior by tacrolimus.
    European journal of pharmacology, 2010, Jan-25, Volume: 626, Issue:2-3

    Topics: Animals; Behavior, Animal; Dermatitis, Atopic; Dexamethasone; Ear; Male; Mice; Mice, Inbred BALB C; Pruritus; Substance P; Tacrolimus

2010
Differential effects of substance P or hemokinin-1 on transient receptor potential channels, TRPV1, TRPA1 and TRPM8, in the rat.
    Neuropeptides, 2010, Volume: 44, Issue:1

    Topics: Acrolein; Animals; Ankyrins; Behavior, Animal; Calcium Channels; Diterpenes; Injections, Spinal; Male; Menthol; Pruritus; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Tachykinins; TRPA1 Cation Channel; TRPC Cation Channels; TRPM Cation Channels; TRPV Cation Channels

2010
Effect of epinastine hydrochloride on murine self-scratching behavior after skin-scratching stimulation.
    Archives of dermatological research, 2010, Volume: 302, Issue:1

    Topics: Administration, Oral; Animals; Behavior Control; Cell Degranulation; Dibenzazepines; Histamine H1 Antagonists, Non-Sedating; Imidazoles; Immunohistochemistry; Mast Cells; Mice; Mice, Inbred ICR; Nerve Growth Factor; Pruritus; Sensory Receptor Cells; Skin Diseases; Substance P

2010
Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats.
    Neuroreport, 2010, Mar-10, Volume: 21, Issue:4

    Topics: Animals; Drug Combinations; Hindlimb; Immunohistochemistry; Injections, Intradermal; Male; Microinjections; Neurotransmitter Agents; Posterior Horn Cells; Pruritus; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Serotonin; Serotonin Agents; Substance P

2010
Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis.
    Journal of dermatological science, 2010, Volume: 58, Issue:3

    Topics: Adrenergic Fibers; Adult; Aged; Aged, 80 and over; Biopsy; Chronic Disease; Dermatitis, Atopic; Dermis; Female; Fluorescent Antibody Technique; Humans; Male; Middle Aged; Prurigo; Pruritus; Sensory Receptor Cells; Substance P

2010
Inhibitory effect of methanol extract of Ganoderma lucidum on acute itch-associated responses in mice.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:5

    Topics: Afferent Pathways; Animals; Behavior, Animal; Biological Products; Dose-Response Relationship, Drug; Histamine; Male; Mice; Mice, Inbred ICR; Oligopeptides; p-Methoxy-N-methylphenethylamine; Phytotherapy; Pruritus; Receptor, PAR-2; Receptors, Serotonin; Reishi; Serotonin; Skin; Substance P

2010
Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P.
    Molecular pain, 2010, May-24, Volume: 6

    Topics: Animals; Calcium; Histamine; Male; Mice; Mice, Inbred C57BL; Mole Rats; Posterior Horn Cells; Pruritus; Rats; Spinal Cord; Substance P

2010
Association of stress with symptoms of atopic dermatitis.
    Acta dermato-venereologica, 2010, Volume: 90, Issue:6

    Topics: Adolescent; Adult; Anxiety; Biopsy; Case-Control Studies; Child; Depression; Dermatitis, Atopic; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nerve Growth Factor; Neuropeptide Y; Prognosis; Pruritus; Quality of Life; Receptors, Corticotropin-Releasing Hormone; Republic of Korea; Severity of Illness Index; Skin; Stress, Psychological; Substance P; Surveys and Questionnaires; Young Adult

2010
More on aprepitant for erlotinib-induced pruritus.
    The New England journal of medicine, 2011, 02-03, Volume: 364, Issue:5

    Topics: Antiemetics; Aprepitant; Erlotinib Hydrochloride; Humans; Morpholines; Neurokinin-1 Receptor Antagonists; Off-Label Use; Protein Kinase Inhibitors; Pruritus; Quinazolines; Substance P

2011
Topical cholecystokinin depresses itch-associated scratching behavior in mice.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:4

    Topics: Administration, Topical; Animals; Behavior, Animal; Calcium; Cell Degranulation; Chemokines, CC; Cholagogues and Choleretics; Cholecystokinin; Dermis; Female; Gene Expression; Keratinocytes; Mast Cells; Mice; Mice, Inbred ICR; Neurotransmitter Agents; Pruritus; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Substance P

2011
Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2011, Volume: 50, Issue:2

    Topics: Animals; Antipruritics; Dermatitis; Female; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Pruritus; Quinuclidines; Rodent Diseases; Skin Ulcer; Substance P

2011
Glycyrrhetinic acid prevents cutaneous scratching behavior in mice elicited by substance P or PAR-2 agonist.
    European journal of pharmacology, 2011, Nov-16, Volume: 670, Issue:1

    Topics: Animals; Antipruritics; Behavior, Animal; Glycyrrhetinic Acid; Histamine; Leukotriene B4; Male; Mice; Mice, Inbred ICR; Pruritus; Receptor, PAR-2; Skin; Substance P

2011
The feeling of healing.
    Plastic and reconstructive surgery, 2012, Volume: 129, Issue:1

    Topics: Cicatrix; Humans; Neurotransmitter Agents; Pruritus; Sensation; Substance P; Wound Healing

2012
Do acupuncture meridians exist? Correlation with referred itch (mitempfindung) stimulus and referral points.
    Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2012, Volume: 30, Issue:1

    Topics: Acupuncture Points; Acupuncture Therapy; Humans; Male; Mast Cells; Meridians; Merkel Cells; Pain, Referred; Pruritus; Substance P

2012
Expression of selected neuropeptides in pathogenesis of bullous pemphigoid and dermatitis herpetiformis.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 2012, Volume: 63, Issue:1

    Topics: Aged; Aged, 80 and over; Calcitonin Gene-Related Peptide; Corticotropin-Releasing Hormone; Dermatitis Herpetiformis; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neurokinin B; Neuropeptides; Pemphigoid, Bullous; Pruritus; Receptor, Endothelin B; Substance P

2012
Investigation of serum substance P status in patients with chronic pruritic skin lesions due to sulfur mustard: a cross-sectional study.
    Cutaneous and ocular toxicology, 2013, Volume: 32, Issue:1

    Topics: Adult; Cross-Sectional Studies; Dermatitis, Atopic; Humans; Iraq; Male; Middle Aged; Mustard Gas; Pruritus; Quality of Life; Substance P; Veterans

2013
Artemin causes hypersensitivity to warm sensation, mimicking warmth-provoked pruritus in atopic dermatitis.
    The Journal of allergy and clinical immunology, 2012, Volume: 130, Issue:3

    Topics: Animals; Cell Differentiation; Cell Proliferation; Dermatitis, Atopic; Female; Hot Temperature; Humans; Hyperalgesia; Hypersensitivity; Immunohistochemistry; Mice; Mice, Inbred C57BL; Nerve Growth Factor; Nerve Tissue Proteins; Neurites; Pruritus; Sensory Thresholds; Skin; Substance P; TRPV Cation Channels

2012
In vitro and in vivo pharmacological characterization of the main metabolites of nalfurafine hydrochloride.
    European journal of pharmacology, 2012, Nov-15, Volume: 695, Issue:1-3

    Topics: Animals; Antipruritics; Behavior, Animal; HEK293 Cells; Humans; Male; Mice; Morphinans; Pruritus; Receptors, Opioid; Spiro Compounds; Substance P

2012
Narrow band ultraviolet B irradiations cause alteration in interleukin-31 serum level in psoriatic patients.
    Archives of dermatological research, 2013, Volume: 305, Issue:3

    Topics: Adult; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Corticotropin-Releasing Hormone; Female; Humans; Interleukins; Male; Middle Aged; Pruritus; Psoriasis; Skin; Substance P; Surveys and Questionnaires; Ultraviolet Rays; Ultraviolet Therapy

2013
Roles for substance P and gastrin-releasing peptide as neurotransmitters released by primary afferent pruriceptors.
    Journal of neurophysiology, 2013, Volume: 109, Issue:3

    Topics: Animals; Calcium; Chloroquine; Ganglia, Spinal; Gastrin-Releasing Peptide; Histamine; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Oligopeptides; Peptide Fragments; Pruritus; Receptors, Bombesin; Sensory Receptor Cells; Serotonin; Signal Transduction; Substance P

2013
Nitric oxide enhances substance P-induced itch-associated responses in mice.
    British journal of pharmacology, 2003, Volume: 138, Issue:1

    Topics: Adult; Animals; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred ICR; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase; Pruritus; Receptors, Neurokinin-1; Substance P

2003
Deletion of the preprotachykinin A gene in mice does not reduce scratching behavior elicited by intradermal serotonin.
    Neuroscience letters, 2003, Mar-13, Volume: 339, Issue:1

    Topics: Animals; Injections, Intradermal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Precursors; Pruritus; Serotonin; Substance P; Synaptic Transmission; Tachykinins

2003
[Antipruritic effects of pimecrolimus and tacrolimus].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2003, Volume: 54, Issue:5

    Topics: Administration, Topical; Animals; Antipruritics; Calcineurin Inhibitors; Dermatitis, Allergic Contact; Humans; Immunosuppressive Agents; Mast Cells; Microscopy, Fluorescence; Neuropeptides; Pruritus; Skin; Substance P; Tacrolimus; Treatment Outcome

2003
Inhibitory effect of the repeated treatment with Unsei-in on substance P-induced itch-associated responses through the downregulation of the expression of NK(1) tachykinin receptor in mice.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:6

    Topics: Administration, Oral; Animals; Antipruritics; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Injections, Intradermal; Male; Mice; Mice, Inbred ICR; Pruritus; Receptors, Neurokinin-1; Skin; Substance P

2003
Involvement of histamine H3 receptors in scratching behaviour in mast cell-deficient mice.
    The British journal of dermatology, 2003, Volume: 149, Issue:1

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Injections, Intradermal; Mast Cells; Mice; Mice, Inbred Strains; Pruritus; Receptors, Histamine H3; Skin; Substance P

2003
Involvement of central mu-opioid system in the scratching behavior in mice, and the suppression of it by the activation of kappa-opioid system.
    European journal of pharmacology, 2003, Sep-05, Volume: 477, Issue:1

    Topics: Animals; Antipruritics; Behavior, Animal; Injections, Intraventricular; Injections, Subcutaneous; Ketotifen; Male; Mice; Morphinans; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pruritus; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spiro Compounds; Substance P

2003
Repeated treatment with the traditional medicine Unsei-in inhibits substance P-induced itch-associated responses through downregulation of the expression of nitric oxide synthase 1 in mice.
    Journal of pharmacological sciences, 2004, Volume: 94, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Down-Regulation; Drugs, Chinese Herbal; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pruritus; Substance P

2004
Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures.
    Experimental dermatology, 2004, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Biopsy; Brain; Calcitonin Gene-Related Peptide; Capillaries; Capsaicin; Cell Line; Child; Eccrine Glands; Epidermal Cells; Epidermis; Epithelial Cells; Gene Expression; Hair Follicle; Humans; Mast Cells; Middle Aged; Nerve Fibers; Neurons, Afferent; Nociceptors; Pruritus; Rats; Receptors, Drug; Sebaceous Glands; Spinal Cord; Substance P

2004
Substance P axons and sensory threshold increase in burn-graft human skin.
    The Journal of surgical research, 2004, May-15, Volume: 118, Issue:2

    Topics: Adult; Axons; Burns; Dermatologic Surgical Procedures; Humans; Middle Aged; Nerve Regeneration; Nociceptors; Pain; Pruritus; Recovery of Function; Sensory Thresholds; Skin; Skin Transplantation; Substance P; Touch; Vibration

2004
Involvement of substance P in scratching behaviour in an atopic dermatitis model.
    European journal of pharmacology, 2004, May-03, Volume: 491, Issue:2-3

    Topics: Animals; Behavior, Animal; Dermatitis, Atopic; Disease Models, Animal; Male; Mice; Neurokinin-1 Receptor Antagonists; Pruritus; Receptors, Neurokinin-1; Substance P; Tachykinins

2004
Inhibition of scratching behaviour caused by contact dermatitis in histidine decarboxylase gene knockout mice.
    Experimental dermatology, 2005, Volume: 14, Issue:3

    Topics: Animals; Behavior, Animal; Cadherins; Dermatitis, Contact; Histamine; Histidine Decarboxylase; Mice; Mice, Knockout; Neural Conduction; Proto-Oncogene Proteins c-fos; Pruritus; Sensation; Spinal Cord; Substance P

2005
Pruritus after intrathecal baclofen withdrawal: A retrospective study.
    Archives of physical medicine and rehabilitation, 2005, Volume: 86, Issue:3

    Topics: Baclofen; GABA Agonists; Humans; Incidence; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Pruritus; Retrospective Studies; Substance P; Substance Withdrawal Syndrome

2005
Antipruritic effect of ginsenoside rb1 and compound k in scratching behavior mouse models.
    Journal of pharmacological sciences, 2005, Volume: 99, Issue:1

    Topics: Animals; Antipruritics; Behavior, Animal; Capillary Permeability; Disease Models, Animal; Ginsenosides; Histamine; Inhibitory Concentration 50; Male; Mice; p-Methoxy-N-methylphenethylamine; Phthalazines; Pruritus; Substance P; Time Factors

2005
Role of substance P on histamine H(3) antagonist-induced scratching behavior in mice.
    Journal of pharmacological sciences, 2006, Volume: 100, Issue:4

    Topics: Amphetamines; Animals; Behavior, Animal; Histamine Antagonists; Imidazoles; Isothiuronium; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Pruritus; Receptors, Histamine H1; Receptors, Histamine H3; Substance P

2006
Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch.
    Pain, 2006, Dec-15, Volume: 126, Issue:1-3

    Topics: Adult; Bradykinin; Cross-Over Studies; Dermatitis, Atopic; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Male; Pain; Pruritus; Serotonin; Single-Blind Method; Substance P; Urticaria; Water

2006
Suppression by bepotastine besilate of substance P-induced itch-associated responses through the inhibition of the leukotriene B4 action in mice.
    European journal of pharmacology, 2006, Oct-10, Volume: 547, Issue:1-3

    Topics: Administration, Oral; Animals; Behavior, Animal; Calcium; Dose-Response Relationship, Drug; Ganglia, Spinal; Histamine H1 Antagonists; Leukotriene B4; Male; Mice; Mice, Inbred ICR; Neurons; Neutrophils; Piperidines; Pruritus; Pyridines; Skin; Substance P

2006
How important are NK1 receptors for influencing microvascular inflammation and itch in the skin? Studies using Phoneutria nigriventer venom.
    Vascular pharmacology, 2006, Volume: 45, Issue:4

    Topics: Administration, Topical; Animals; Dose-Response Relationship, Drug; Edema; Female; Injections, Intradermal; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Piperidines; Pruritus; Quinuclidines; Receptors, Neurokinin-1; Skin; Spider Venoms; Substance P; Vasculitis, Leukocytoclastic, Cutaneous

2006
Neuronal conditions of spinal cord in dermatitis are improved by olopatadine.
    European journal of pharmacology, 2006, Oct-10, Volume: 547, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cyclopropanes; Dermatitis, Contact; Dibenzoxepins; Dose-Response Relationship, Drug; Eczema; Female; Histamine H1 Antagonists; Immunohistochemistry; Mice; Mice, Inbred BALB C; Neurons; Olopatadine Hydrochloride; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Pruritus; Skin; Substance P

2006
Deletion of mu- and kappa-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior.
    The Journal of investigative dermatology, 2007, Volume: 127, Issue:6

    Topics: Animals; Brain; CD4-Positive T-Lymphocytes; Chronic Disease; Dermatitis; Dermis; Epidermis; Female; Gene Expression; Homeostasis; Hypertrophy; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Endings; Pruritus; Receptors, Opioid, kappa; Receptors, Opioid, mu; RNA, Messenger; Substance P; Ubiquitin Thiolesterase

2007
Changes in cutaneous sensory nerve fibers induced by skin-scratching in mice.
    Journal of dermatological science, 2007, Volume: 46, Issue:1

    Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Dermis; Epidermis; Fluorescent Antibody Technique; Male; Mice; Mice, Inbred ICR; Pruritus; Sensory Receptor Cells; Signal Transduction; Substance P; Ubiquitin Thiolesterase

2007
Study of substance P and its receptor neurokinin-1 in psoriasis and their relation to chronic stress and pruritus.
    Archives of dermatological research, 2007, Volume: 299, Issue:2

    Topics: Adult; Aged; Chronic Disease; Female; Gene Expression Regulation; Humans; Hydrocortisone; Male; Middle Aged; Pain Measurement; Pruritus; Psoriasis; Receptors, Neurokinin-1; Saliva; Skin; Stress, Psychological; Substance P

2007
Psychological stress can trigger atopic dermatitis in NC/Nga mice: an inhibitory effect of corticotropin-releasing factor.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:3

    Topics: Animals; Antibodies, Blocking; Corticosterone; Corticotropin-Releasing Hormone; Cytokines; Defecation; Dermatitis, Atopic; Immunoglobulin E; Immunohistochemistry; Lymph Nodes; Male; Mice; Pruritus; Stress, Psychological; Substance P; Water

2008
Dietary pulverized konjac glucomannan suppresses scratching behavior and skin inflammatory immune responses in NC/Nga mice.
    International archives of allergy and immunology, 2007, Volume: 144, Issue:2

    Topics: Animals; Dermatitis, Atopic; Dietary Carbohydrates; Disease Models, Animal; Ear; Eosinophilia; Immunoglobulin E; Immunoglobulin G; Interferon-alpha; Interleukin-10; Interleukin-4; Keratosis; Male; Mannans; Mastocytosis, Cutaneous; Mice; Mice, Inbred Strains; Pruritus; Skin; Substance P

2007
Rapid changes in substance P signaling and neutral endopeptidase induced by skin-scratching stimulation in mice.
    Journal of dermatological science, 2007, Volume: 48, Issue:2

    Topics: Animals; Cell Degranulation; Dermatitis, Contact; Dinitrofluorobenzene; Male; Mast Cells; Mice; Mice, Inbred ICR; Neprilysin; Neurokinin-1 Receptor Antagonists; Physical Stimulation; Pruritus; Receptors, Neurokinin-1; Skin; Skin Physiological Phenomena; Substance P

2007
A transient unresponsive state of self-scratching behaviour is induced in mice by skin-scratching stimulation.
    Experimental dermatology, 2007, Volume: 16, Issue:9

    Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Peptide Fragments; Physical Stimulation; Pruritus; Quinuclidines; Self Stimulation; Signal Transduction; Skin Physiological Phenomena; Substance P

2007
Erratum to "changes in cutaneous sensory nerve fibers induced by skin-scratching in mice".
    Journal of dermatological science, 2007, Volume: 47, Issue:2

    Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Dermis; Epidermis; Fluorescent Antibody Technique; Male; Mice; Mice, Inbred ICR; Nerve Fibers; Nerve Growth Factor; Neurons, Afferent; Pruritus; Sensory Receptor Cells; Signal Transduction; Substance P; Ubiquitin Thiolesterase

2007
Pathophysiology of nocturnal scratching in childhood atopic dermatitis: the role of brain-derived neurotrophic factor and substance P.
    The British journal of dermatology, 2007, Volume: 157, Issue:5

    Topics: Brain-Derived Neurotrophic Factor; Chemokines; Child; Dermatitis, Atopic; Eosinophils; Female; Humans; Immunoglobulin E; Male; Pruritus; Quality of Life; Severity of Illness Index; Sleep; Substance P

2007
The role of selected neuropeptides in pathogenesis of atopic dermatitis.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2008, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Calcitonin Gene-Related Peptide; Case-Control Studies; Dermatitis, Atopic; Female; Humans; Immunoglobulin E; Inflammation; Male; Middle Aged; Neuropeptide Y; Pain Measurement; Pruritus; Severity of Illness Index; Skin; Substance P

2008
Effects of topical application of tacrolimus on acute itch-associated responses in mice.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:4

    Topics: Administration, Topical; Aedes; Animals; Antipruritics; Behavior, Animal; Capsaicin; Female; Histamine; Immunosuppressive Agents; Male; Mice; Mice, Inbred ICR; Pruritus; Serotonin; Substance P; Tacrolimus

2008
Potentiation of histamine-induced itch and flare responses in human skin by the enkephalin analogue FK-33-824, beta-endorphin and morphine.
    Archives of dermatological research, 1982, Volume: 274, Issue:1-2

    Topics: Adolescent; Adult; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dinoprostone; Drug Synergism; Endorphins; Enkephalin, Methionine; Female; Histamine; Humans; Indomethacin; Male; Middle Aged; Morphine; Naloxone; Prostaglandins E; Pruritus; Skin; Substance P; Vasoactive Intestinal Peptide

1982
Peptidergic (neurotensin, VIP, substance P) nerve fibres in the skin. Immunohistochemical evidence of an involvement of neuropeptides in nociception, pruritus and inflammation.
    The British journal of dermatology, 1983, Volume: 109 Suppl 25

    Topics: Animals; Arteries; Cats; Dermatitis; Dogs; Gastrointestinal Hormones; Guinea Pigs; Haplorhini; Humans; Nerve Fibers; Neurotensin; Nociceptors; Pruritus; Rats; Skin; Substance P; Vasoactive Intestinal Peptide; Veins

1983
Influence of calcitonin gene-related peptide on histamine- and substance P-induced itch, flare and weal in humans.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1993, Volume: 6, Issue:3

    Topics: Adult; Calcitonin Gene-Related Peptide; Dermatitis, Contact; Female; Histamine; Humans; Injections, Subcutaneous; Male; Pruritus; Substance P

1993
Scratching behavior induced by pruritogenic but not algesiogenic agents in mice.
    European journal of pharmacology, 1995, Mar-14, Volume: 275, Issue:3

    Topics: Animals; Behavior, Animal; Capsaicin; Formaldehyde; Histamine; Male; Mice; p-Methoxy-N-methylphenethylamine; Pain; Pruritus; Substance P

1995
Histamine-induced itch and alloknesis (itchy skin) in atopic eczema patients and controls.
    Acta dermato-venereologica, 1995, Volume: 75, Issue:5

    Topics: Administration, Cutaneous; Adolescent; Adult; Analysis of Variance; Cold Temperature; Dermatitis, Atopic; Female; Forearm; Histamine; Humans; Injections, Intradermal; Iontophoresis; Male; Middle Aged; Neurons, Afferent; Pruritus; Scapula; Skin; Skin Temperature; Substance P

1995
Pruritogenic effects of mitogen-stimulated peripheral blood mononuclear cells in atopic eczema.
    Acta dermato-venereologica, 1995, Volume: 75, Issue:6

    Topics: Adult; Cells, Cultured; Concanavalin A; Cytokines; Dermatitis, Atopic; Histamine; Humans; Leukocytes, Mononuclear; Mitogens; Phytohemagglutinins; Pruritus; Substance P

1995
Clinical and pathophysiological aspects of hydroxyethyl starch-induced pruritus: evaluation of 96 cases.
    Dermatology (Basel, Switzerland), 1996, Volume: 192, Issue:3

    Topics: Biopsy, Needle; Drug Eruptions; Humans; Hydroxyethyl Starch Derivatives; Infusions, Intravenous; Patch Tests; Plasma Substitutes; Prospective Studies; Pruritus; Radioimmunoassay; Retrospective Studies; Substance P

1996
Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:3

    Topics: Animals; Male; Mast Cells; Mice; Mice, Inbred ICR; Morphine; Naloxone; p-Methoxy-N-methylphenethylamine; Pruritus; Receptors, Neurokinin-1; Substance P

1998
Inhibitory effects of methanol extracts of herbal medicines on substance P-induced itch-scratch response.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:5

    Topics: Animals; Antipruritics; Disease Models, Animal; Male; Methanol; Mice; Mice, Inbred ICR; Phytotherapy; Plants, Medicinal; Pruritus; Substance P

2000
Involvement of blockade of leukotriene B(4) action in anti-pruritic effects of emedastine in mice.
    European journal of pharmacology, 2000, Oct-06, Volume: 406, Issue:1

    Topics: Animals; Anti-Allergic Agents; Benzimidazoles; Dose-Response Relationship, Drug; Histamine; Injections, Intradermal; Leukotriene B4; Male; Mice; Mice, Inbred ICR; Pruritus; Serotonin; Substance P

2000
Characterization of itch-associated responses of NC mice with mite-induced chronic dermatitis.
    Journal of dermatological science, 2001, Volume: 25, Issue:1

    Topics: Animals; Attention; Chronic Disease; Dermatitis; Female; Histamine; Immunoglobulin E; Mice; Mice, Inbred Strains; Mites; Naltrexone; Narcotic Antagonists; Pruritus; Serotonin; Substance P

2001
Intradermal skin test reactivity to histamine and substance P is blunted in dogs with atopic dermatitis.
    Veterinary dermatology, 2001, Volume: 12, Issue:3

    Topics: Animals; Case-Control Studies; Dermatitis, Atopic; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Histamine; Intradermal Tests; Male; Pruritus; Skin; Substance P; Time Factors

2001
Antipruritic activity of the kappa-opioid receptor agonist, TRK-820.
    European journal of pharmacology, 2002, Jan-25, Volume: 435, Issue:2-3

    Topics: Animals; Antipruritics; Chlorpheniramine; Disease Models, Animal; Histamine; Histamine H1 Antagonists; Ketotifen; Male; Mice; Mice, Inbred ICR; Morphinans; Motor Activity; Naltrexone; Pruritus; Receptors, Opioid, kappa; Spiro Compounds; Substance P

2002
Inhibitory effects of azelastine on substance P-induced itch-associated response in mice.
    European journal of pharmacology, 2002, Feb-02, Volume: 436, Issue:3

    Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Leukotriene B4; Male; Mice; Mice, Inbred ICR; Neutrophils; Phthalazines; Pruritus; Skin; Substance P

2002
Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice.
    The Journal of investigative dermatology, 2001, Volume: 117, Issue:6

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Enzyme Inhibitors; Glucocorticoids; Immunosuppressive Agents; Indomethacin; Keratinocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mast Cells; Mice; Mice, Inbred ICR; Mice, Mutant Strains; Phenylpropionates; Phospholipases A; Pruritus; Receptors, Leukotriene B4; Receptors, Neurokinin-1; Substance P

2001
Immunohistochemical findings in notalgia paresthetica.
    Dermatology (Basel, Switzerland), 2002, Volume: 204, Issue:2

    Topics: Adult; Aged; Back Pain; Biomarkers; Epidermis; Female; Humans; Hyperpigmentation; Immunohistochemistry; Male; Middle Aged; Polyradiculoneuropathy; Pruritus; S100 Proteins; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide

2002
Study on pruritus in hemodialysis patients and the antipruritic effect of neurotropin: plasma levels of substance P, somatostatin, IgE, PTH and histamine.
    Nihon Jinzo Gakkai shi, 1990, Volume: 32, Issue:3

    Topics: Adjuvants, Immunologic; Female; Histamine; Humans; Immunoglobulin E; Male; Middle Aged; Parathyroid Hormone; Polysaccharides; Pruritus; Renal Dialysis; Somatostatin; Substance P

1990
Nasal challenge with serotonin in asymptomatic hay fever patients.
    Allergy, 1987, Volume: 42, Issue:6

    Topics: Adult; Airway Resistance; Female; Humans; Male; Mucus; Nasal Mucosa; Nasal Provocation Tests; Pruritus; Rhinitis, Allergic, Seasonal; Serotonin; Sneezing; Substance P

1987