Page last updated: 2024-08-23

substance p and Irritable Bowel Syndrome

substance p has been researched along with Irritable Bowel Syndrome in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (50.00)29.6817
2010's12 (46.15)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Chen, Y; Hou, YJ; Jiang, HL; Li, Y; Wang, K; Yao, JP; Zhou, SY1
Dekker, J; Hamer, HM; Helyes, Z; Jonkers, DM; Keszthelyi, D; Ludidi, S; Masclee, AA; Szolcsányi, J; Troost, FJ; Vanhoutvin, S; Venema, K1
Neri, M1
Choi, HS; Jang, KS; Jun, DW; Lee, HL; Lee, KN; Lee, OY; Lee, SP; Sim, J; Sohn, W; Yoon, BC1
Bian, ZX; Lin, ZS; Tsang, SW; Xiao, HT; Zhong, L1
Kuang, HX; Wang, JW; Yin, Y; Zhao, WJ; Zhao, XY; Zhong, L1
Anqi, W; Chunhui, B; Jie, S; Jimeng, Z; Weijun, T; Xiaojun, Y; Yin, S; Yuehua, C; Zhenzhong, L1
Huang, D; Liang, LX; Liang, WJ; Luo, HS; Zhang, FC; Zhang, G1
Lu, Y; Wang, SJ; Wang, Y; Zhang, YN; Zhao, HJ1
Chen, H; Ding, M; Du, X; Fang, M; Fang, Y; Fu, X; Guo, F; Teng, W; Zhang, H1
Barrett, KE; Camilleri, M; Sellin, JH1
Ju, JM; Kong, M; Li, SL; Li, X; Lu, M; Luo, YH; Mao, Q; Shen, MQ; Shi, L; Wang, YY; Wang, ZG; Xu, JD; Zhou, SS1
Lin, L; Lin, Z; Shi, R; Wang, M; Yan, Y; Zhang, H1
Guo, J; Hu, XG; Meng, J; Shen, H; Xu, D; Yang, XB; Zhao, Y1
Jiang, B; Liu, HR; Ma, XP; Tan, LY; Wu, HG; Yang, L; Yang, Y1
Hu, R; Tang, F1
Chai, JY; Guan, HQ; Han, XW; Wang, DS; Wang, J; Wang, YJ; Zhao, JR1
Dong, WZ; Gong, YF; Li, ZS; Xu, GM; Yin, N; Zhu, AY; Zou, DW; Zou, XP1
Duffy, RA1
Fang, XC; Pan, GZ; Wang, LH1
Bozymski, EM; Davies, MJ; Johnson, DA; Morteau, O; Palsson, OS; Sartor, RB; Turner, MJ; Whitehead, WE; Woosley, JT1
Dong, WZ; Gong, YF; Li, ZS; Man, XH; Sun, ZX; Xu, GM; Yin, N; Zhu, AY; Zou, DW; Zou, XP1
Crentsil, V1
Bercik, P; Blennerhassett, P; Collins, SM; Huang, XX; Jackson, W; Mao, Y; Rochat, F; Verdú, EF; Verma-Gandhu, M; Wang, L1
Peng, LH; Sun, G; Wang, WF; Yang, YS1
Cui, YH; Jiang, B; Kou, ST; Liu, HR; Shi, DR; Shi, Z; Wu, HG; Zhou, EH1

Reviews

3 review(s) available for substance p and Irritable Bowel Syndrome

ArticleYear
Traditional Chinese medicine formulas for irritable bowel syndrome: from ancient wisdoms to scientific understandings.
    The American journal of Chinese medicine, 2015, Volume: 43, Issue:1

    Topics: Cholecystokinin; Drugs, Chinese Herbal; Gastrointestinal Motility; Humans; Hypothalamo-Hypophyseal System; Intestines; Irritable Bowel Syndrome; Medicine, Chinese Traditional; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Pituitary-Adrenal System; Randomized Controlled Trials as Topic; Serotonin; Signal Transduction; Somatostatin; Substance P; Vasoactive Intestinal Peptide

2015
Pathophysiology, Evaluation, and Management of Chronic Watery Diarrhea.
    Gastroenterology, 2017, Volume: 152, Issue:3

    Topics: C-Reactive Protein; Chromogranins; Chronic Disease; Diarrhea; Feces; Gastrointestinal Motility; Humans; Inflammation; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Intestines; Irritable Bowel Syndrome; Lactoferrin; Leukocyte L1 Antigen Complex; Osmolar Concentration; Permeability; Prostaglandins; Serotonin; Substance P

2017
Potential therapeutic targets for neurokinin-1 receptor antagonists.
    Expert opinion on emerging drugs, 2004, Volume: 9, Issue:1

    Topics: Analgesics; Anti-Anxiety Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antiemetics; Antineoplastic Agents; Antitussive Agents; Anxiety; Asthma; Clinical Trials as Topic; Cough; Cystitis; Depression; Drug Design; Humans; Inflammation; Irritable Bowel Syndrome; Neoplasms; Neurokinin-1 Receptor Antagonists; Pain; Substance P; Vomiting

2004

Trials

1 trial(s) available for substance p and Irritable Bowel Syndrome

ArticleYear
Comparative effect of electroacupuncture and moxibustion on the expression of substance P and vasoactive intestinal peptide in patients with irritable bowel syndrome.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2015, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Electroacupuncture; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Moxibustion; Substance P; Vasoactive Intestinal Peptide; Young Adult

2015

Other Studies

22 other study(ies) available for substance p and Irritable Bowel Syndrome

ArticleYear
[Study on the mechanism of electroacupuncture repairing intestinal barrier via regulating mast cell in rats with diarrhea-predominant irritable bowel syndrome].
    Zhen ci yan jiu = Acupuncture research, 2023, Mar-25, Volume: 48, Issue:3

    Topics: Acupuncture Points; Animals; Diarrhea; Electroacupuncture; Female; Irritable Bowel Syndrome; Mast Cells; Occludin; Rats; Rats, Sprague-Dawley; Substance P; Tryptases; Visceral Pain

2023
Alterations in mucosal neuropeptides in patients with irritable bowel syndrome and ulcerative colitis in remission: a role in pain symptom generation?
    European journal of pain (London, England), 2013, Volume: 17, Issue:9

    Topics: Abdominal Pain; Colitis, Ulcerative; Colon, Sigmoid; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Somatostatin; Substance P; TRPV Cation Channels

2013
Irritable bowel syndrome, inflammatory bowel disease and TRPV1: how to disentangle the bundle.
    European journal of pain (London, England), 2013, Volume: 17, Issue:9

    Topics: Abdominal Pain; Colitis, Ulcerative; Colon, Sigmoid; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Somatostatin; Substance P

2013
Mast cell number, substance P and vasoactive intestinal peptide in irritable bowel syndrome with diarrhea.
    Scandinavian journal of gastroenterology, 2014, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Cell Count; Diarrhea; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mast Cells; Middle Aged; Rectum; Sex Factors; Substance P; Vasoactive Intestinal Peptide; Young Adult

2014
Tong Xie Yao Fang relieves irritable bowel syndrome in rats via mechanisms involving regulation of 5-hydroxytryptamine and substance P.
    World journal of gastroenterology, 2015, Apr-21, Volume: 21, Issue:15

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Colon; Defecation; Disease Models, Animal; Drugs, Chinese Herbal; Enteric Nervous System; Gastrointestinal Agents; Gastrointestinal Motility; Hypothalamus; Irritable Bowel Syndrome; Rats, Wistar; Serotonin; Signal Transduction; Substance P; Time Factors

2015
Tryptase and Protease-Activated Receptor 2 Expression Levels in Irritable Bowel Syndrome.
    Gut and liver, 2016, May-23, Volume: 10, Issue:3

    Topics: Abdominal Pain; Adult; Calcitonin Gene-Related Peptide; Case-Control Studies; Colon; Female; Humans; Irritable Bowel Syndrome; Male; Mast Cells; Middle Aged; Receptor, PAR-2; RNA, Messenger; Substance P; Tryptases; Vasoactive Intestinal Peptide

2016
[Effect of Electroacupuncture Intervention on Constipation-predominant Irritable Bow l Syndrome and Colonic CGRP and SP Expression in Rats].
    Zhen ci yan jiu = Acupuncture research, 2016, Volume: 41, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Colon; Constipation; Electroacupuncture; Humans; Irritable Bowel Syndrome; Male; Rats; Rats, Wistar; Substance P

2016
Expression and distribution of SP and its NK1 receptor in the brain-gut axis in neonatal maternally separated rat model with visceral hypersensitivity.
    Genetics and molecular research : GMR, 2016, Aug-30, Volume: 15, Issue:3

    Topics: Animals; Colon; Hyperalgesia; Irritable Bowel Syndrome; Male; Maternal Deprivation; Muscle, Smooth; Myenteric Plexus; Organ Specificity; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord Dorsal Horn; Substance P

2016
Chemical profiles and pharmacological activities of Chang-Kang-Fang, a multi-herb Chinese medicinal formula, for treating irritable bowel syndrome.
    Journal of ethnopharmacology, 2017, Apr-06, Volume: 201

    Topics: Acetic Acid; Animals; Calcitonin Gene-Related Peptide; Colon; Drugs, Chinese Herbal; Irritable Bowel Syndrome; Male; Mice; Phytochemicals; Rats, Sprague-Dawley; Serotonin; Substance P; Vasoactive Intestinal Peptide; Visceral Pain

2017
Correlation of gut hormones with irritable bowel syndrome.
    Digestion, 2008, Volume: 78, Issue:2-3

    Topics: Adult; Aged; Cholecystokinin; Female; Gastrointestinal Hormones; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Neuropeptide Y; Somatostatin; Substance P; Vasoactive Intestinal Peptide

2008
The alleviating pain effect of aqueous extract from tong-xie-yao-fang, on experimental visceral hypersensitivity and its mechanism.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:6

    Topics: Abdominal Pain; Animals; Animals, Newborn; Brain; Colon; Corticotropin-Releasing Hormone; Disease Models, Animal; Drugs, Chinese Herbal; Female; Hyperalgesia; Irritable Bowel Syndrome; Maternal Deprivation; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin; Substance P; Viscera

2009
Effect of electro-acupuncture on substance P, its receptor and corticotropin-releasing hormone in rats with irritable bowel syndrome.
    World journal of gastroenterology, 2009, Nov-07, Volume: 15, Issue:41

    Topics: Animals; Colon; Corticotropin-Releasing Hormone; Disease Models, Animal; Electroacupuncture; Hypothalamus; Irritable Bowel Syndrome; Male; Mast Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P

2009
[Effect of Weichang Anwan on NO and 5-HT in blood serum, SP and MC in colon in IBS-D rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009, Volume: 34, Issue:23

    Topics: Animals; Colon; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Irritable Bowel Syndrome; Mast Cells; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Serotonin; Substance P

2009
[Effects of eye-acupuncture therapy on serum and colonic SP and VIP contents in rats with irritable bowel syndrome].
    Zhen ci yan jiu = Acupuncture research, 2010, Volume: 35, Issue:1

    Topics: Acupuncture Therapy; Animals; Colon; Disease Models, Animal; Eye; Humans; Irritable Bowel Syndrome; Male; Random Allocation; Rats; Substance P; Vasoactive Intestinal Peptide

2010
[The changes of mucosal mast cells and substance P in patients with irritable bowel syndrome].
    Zhonghua nei ke za zhi, 2003, Volume: 42, Issue:9

    Topics: Adult; Aged; Female; Humans; Immunohistochemistry; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mast Cells; Middle Aged; Receptors, Neurokinin-1; Substance P

2003
Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis.
    Gut, 2004, Volume: 53, Issue:8

    Topics: Adult; Calcitonin Gene-Related Peptide; Colonic Diseases, Functional; Diarrhea; Dysentery, Bacillary; Female; Follow-Up Studies; Humans; Interleukin-1; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mast Cells; Nerve Fibers; Phosphopyruvate Hydratase; Risk Factors; Serotonin; Substance P

2004
Elevated vasoactive intestinal peptide concentrations in patients with irritable bowel syndrome.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:7-8

    Topics: Adult; Blotting, Western; Calcitonin Gene-Related Peptide; Dinoprostone; Female; Humans; Immunoassay; Interleukin-1; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Somatostatin; Substance P; Vasoactive Intestinal Peptide

2004
Study of visceral hypersensitivity in irritable bowel syndrome.
    Chinese journal of digestive diseases, 2004, Volume: 5, Issue:3

    Topics: Adult; Case-Control Studies; Defecation; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Mast Cells; Middle Aged; Pain Threshold; Perception; Pressure; Rectum; Substance P

2004
Will corticosteroids and other anti-inflammatory agents be effective for diarrhea-predominant irritable bowel syndrome?
    Medical hypotheses, 2005, Volume: 65, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Budesonide; Cyclooxygenase 2; Cytokines; Diarrhea; Dinoprostone; Disease Models, Animal; Humans; Irritable Bowel Syndrome; Lymphocyte Activation; Membrane Proteins; Mice; Models, Biological; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Substance P; T-Lymphocytes; Trichinella spiralis; Trichinellosis

2005
Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice.
    Gut, 2006, Volume: 55, Issue:2

    Topics: Abdominal Pain; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Culture Media, Conditioned; Dexamethasone; Electromyography; Female; Hyperalgesia; Intestines; Irritable Bowel Syndrome; Mice; Mice, Inbred BALB C; Peroxidase; Physical Stimulation; Probiotics; Substance P

2006
Alternation of substance P-containing neural pathways in a rat model of irritable bowel syndrome with rectal distension.
    Chinese journal of digestive diseases, 2006, Volume: 7, Issue:4

    Topics: Animals; Biomarkers; Central Nervous System; Disease Models, Animal; Intestine, Large; Irritable Bowel Syndrome; Male; Neural Pathways; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Substance P

2006
Regulatory mechanism of electroacupuncture in irritable bowel syndrome: preventing MC activation and decreasing SP VIP secretion.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:6

    Topics: Animals; Electroacupuncture; Immunohistochemistry; Indoles; Irritable Bowel Syndrome; Male; Mast Cells; Rats; Rats, Sprague-Dawley; Substance P; Vasoactive Intestinal Peptide

2008