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substance p and Intervertebral Disc Degeneration

substance p has been researched along with Intervertebral Disc Degeneration in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (61.54)24.3611
2020's5 (38.46)2.80

Authors

AuthorsStudies
Chen, B; Hong, ZF; Liu, H; Liu, J; Xiu, ZB; Zhang, LZ; Zhao, HJ1
Ge, W; He, M; Lin, Y; Pang, J; Sun, H; Zheng, G1
Jin, LY; Li, XF; Luo, Y; Song, XX; Yu, BW1
Chen, J; Huang, B; Li, S; Liu, J; Wei, X; Wu, H; Xiang, Y; Zhao, F1
Chen, Z; Guo, Z; Li, J; Wu, W; Zhang, J; Zhang, X; Zheng, J1
Guo, Z; Li, XF; Shi, S; Song, XX; Yu, BW1
Ahmed, AS; Alkass, K; Berg, S; Druid, H; Hart, DA; Kosek, E; Svensson, CI1
Hodges, PW; James, G; Klyne, DM; Millecamps, M; Stone, LS1
Algenstaedt, P; Friedrichs, B; Hansen-Algenstaedt, N; Rüther, W; Schaefer, C; Schroeder, M; Viezens, L; Wiesner, L1
Binch, AL; Breakwell, LM; Chiverton, N; Cole, AA; Cross, AK; Le Maitre, CL; Michael, AL1
Cho, SK; Hecht, AC; Iatridis, JC; Lai, A; Laudier, DM; Moon, A; Purmessur, D; Skovrlj, B; Winkelstein, BA1
Anderson, DG; Hilibrand, AS; Kepler, CK; Koerner, JD; Markova, DZ; Rihn, JA; Schroeder, GD; Vaccaro, AR1
Freeman, TA; Isaza, JE; Kurtz, SM; Lanman, TH; Steinbeck, MJ; Veruva, SY1

Other Studies

13 other study(ies) available for substance p and Intervertebral Disc Degeneration

ArticleYear
[Visual acupotomy intervention mitigates pain reaction by improving intervertebral disc degeneration and inhibiting apoptosis of nucleus pulposus cells in rabbits with cervical spondylosis].
    Zhen ci yan jiu = Acupuncture research, 2022, Nov-25, Volume: 47, Issue:11

    Topics: Acupuncture Therapy; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Dinoprostone; Intervertebral Disc Degeneration; Male; Meloxicam; Nucleus Pulposus; Pain; Proto-Oncogene Proteins c-bcl-2; Rabbits; Serotonin; Spondylosis; Substance P

2022
Overexpression of TIMP3 inhibits discogenic pain by suppressing angiogenesis and the expression of substance P in nucleus pulposus.
    Molecular medicine reports, 2020, Volume: 21, Issue:3

    Topics: Adenoviridae; Animals; Back Pain; Genetic Vectors; Intervertebral Disc Degeneration; Male; Neovascularization, Pathologic; Nucleus Pulposus; Rats; Rats, Sprague-Dawley; Substance P; Tissue Inhibitor of Metalloproteinase-3; Transduction, Genetic; Up-Regulation

2020
Substance P Mediates Estrogen Modulation Proinflammatory Cytokines Release in Intervertebral Disc.
    Inflammation, 2021, Volume: 44, Issue:2

    Topics: Animals; Biomarkers; Cytokines; Estrogens; Female; Immunohistochemistry; Inflammation; Intervertebral Disc Degeneration; Low Back Pain; Mice; Mice, Inbred C57BL; Nucleus Pulposus; Random Allocation; Real-Time Polymerase Chain Reaction; Substance P

2021
Damage to the human lumbar cartilage endplate and its clinical implications.
    Journal of anatomy, 2021, Volume: 238, Issue:2

    Topics: Adult; Aged; Case-Control Studies; Female; Humans; Hyaline Cartilage; Intervertebral Disc Degeneration; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Nucleus Pulposus; Substance P

2021
Reactive Oxygen Species Mediate Low Back Pain by Upregulating Substance P in Intervertebral Disc Degeneration.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Adult; Aged; Aged, 80 and over; Animals; Humans; Intervertebral Disc Degeneration; Low Back Pain; Male; Middle Aged; Rats; Reactive Oxygen Species; Substance P; Up-Regulation

2021
Estrogen receptors involvement in intervertebral discogenic pain of the elderly women: colocalization and correlation with the expression of Substance P in nucleus pulposus.
    Oncotarget, 2017, Jun-13, Volume: 8, Issue:24

    Topics: Aged; Female; Humans; Intervertebral Disc Degeneration; Intervertebral Disc Displacement; Low Back Pain; Nucleus Pulposus; Receptors, Estrogen; Substance P

2017
NF-κB-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease.
    International journal of molecular sciences, 2019, Feb-03, Volume: 20, Issue:3

    Topics: Adult; Female; Gene Expression Regulation; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Male; Middle Aged; NF-kappa B; NF-kappa B p50 Subunit; Pain; Signal Transduction; Substance P; Transcription Factor RelA; TRPV Cation Channels

2019
ISSLS Prize in Basic science 2019: Physical activity attenuates fibrotic alterations to the multifidus muscle associated with intervertebral disc degeneration.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019, Volume: 28, Issue:5

    Topics: Animals; Collagen Type I; Collagen Type III; Connective Tissue; Connective Tissue Growth Factor; Disease Models, Animal; Fibronectins; Fibrosis; Gene Regulatory Networks; Intervertebral Disc Degeneration; Matrix Metalloproteinase 2; Mice, Knockout; Paraspinal Muscles; Physical Conditioning, Animal; Substance P; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

2019
Chemokine profile of disc degeneration with acute or chronic pain.
    Journal of neurosurgery. Spine, 2013, Volume: 18, Issue:5

    Topics: Acute Pain; Adolescent; Adult; Chemokines; Chronic Pain; Female; Humans; Interleukin-1alpha; Intervertebral Disc Degeneration; Intervertebral Disc Displacement; Male; Matrix Metalloproteinase 3; Middle Aged; Substance P; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Young Adult

2013
Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration.
    Arthritis research & therapy, 2014, Aug-20, Volume: 16, Issue:5

    Topics: Adult; Aged; Angiogenesis Inducing Agents; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carrier Proteins; Cell Line, Tumor; Cells, Cultured; Cytokines; Gene Expression Regulation; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Middle Aged; Nerve Growth Factor; Nerve Growth Factors; Receptors, Nerve Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Substance P; Vascular Endothelial Growth Factor A; Young Adult

2014
Annular puncture with tumor necrosis factor-alpha injection enhances painful behavior with disc degeneration in vivo.
    The spine journal : official journal of the North American Spine Society, 2016, Volume: 16, Issue:3

    Topics: Animals; Annulus Fibrosus; Behavior, Animal; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Injections; Intervertebral Disc; Intervertebral Disc Degeneration; Lumbar Vertebrae; Male; Nerve Growth Factor; Pain; Punctures; Random Allocation; Rats; Rats, Sprague-Dawley; Substance P; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2016
The Effect of Substance P on an Intervertebral Disc Rat Organ Culture Model.
    Spine, 2016, Dec-15, Volume: 41, Issue:24

    Topics: Animals; Cells, Cultured; Cytokines; Interleukin-1beta; Intervertebral Disc; Intervertebral Disc Degeneration; Organ Culture Techniques; Rats; Real-Time Polymerase Chain Reaction; Substance P; Up-Regulation

2016
Periprosthetic UHMWPE Wear Debris Induces Inflammation, Vascularization, and Innervation After Total Disc Replacement in the Lumbar Spine.
    Clinical orthopaedics and related research, 2017, Volume: 475, Issue:5

    Topics: Adult; Biopsy; Cytokines; Device Removal; Discitis; Female; Humans; Immunohistochemistry; Inflammation Mediators; Intervertebral Disc; Intervertebral Disc Degeneration; Low Back Pain; Lumbar Vertebrae; Macrophages; Male; Middle Aged; Neovascularization, Pathologic; Pain Measurement; Pain, Postoperative; Polyethylenes; Prosthesis Design; Reoperation; Risk Factors; Stress, Mechanical; Substance P; Time Factors; Total Disc Replacement; Treatment Outcome; United States; Vascular Endothelial Growth Factor A; Young Adult

2017