Page last updated: 2024-08-23

substance p and Injuries, Spinal Cord

substance p has been researched along with Injuries, Spinal Cord in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.00)18.7374
1990's9 (22.50)18.2507
2000's15 (37.50)29.6817
2010's13 (32.50)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Chen, Z; Shi, L; Wang, N; Xu, X; Zheng, Y1
Chen, Z; Jiang, MH; Li, G; Lu, D; Xiang, AP; Yang, L; Ye, J1
Leonard, AV; Thornton, E; Vink, R1
Ahn, W; Chi, GF; Chung, E; Jiang, MH; Lim, JE; Son, Y; Zhang, M1
Blumbergs, PC; Leonard, AV; Manavis, J; Vink, R1
Carlsson-Jonsson, A; Fransson, R; Gao, T; Hao, JX; Nyberg, F; Sandström, A; Wiesenfeld-Hallin, Z; Xu, XJ1
Herrity, AN; Hubscher, CH; Petruska, JC; Rau, KK; Stirling, DP1
Bae, JS; Cho, DC; Kim, HJ; Kim, KT; Park, SW1
Bai, CH; Ma, XL1
Bernabé, J; Chéhensse, C; Clément, P; Giuliano, F; Joussain, C1
Chen, L; Han, LR; Li, H; Liu, HJ; Yan, H; Yan, J; Yang, XF1
Baumbauer, KM; Hillyer, JE; Hoy, KC; Joynes, RL; Mintz, EM; Patterson, AM; Young, EE1
Held-Feindt, J; Knerlich-Lukoschus, F; Lucius, R; Mehdorn, HM; von der Ropp-Brenner, B1
LI, RZ; ZENG, FS; ZHOU, MW1
Ahn, W; Chi, GF; Choi, H; Chung, E; Hong, HS; Jiang, MH; Kim, DW; Kim, J; Lim, JE; Son, Y1
Gil, YC; Han, SW; Hong, CH; Kim, JH; Lee, HY; Lee, WH; Noh, JY1
Jang, JH; Leem, JW; Nam, TS; Paik, KS1
Lappi, DA; Mantyh, PW; Vierck, CJ; Yezierski, RP; Yu, CG1
Wang, TH; Xu, XY; Zhang, LS; Zhang, W; Zhao, XJ; Zhou, X1
Fujiuchi, A; Hara, T; Imai, A; Kanai, Y; Nakazato, E1
Brown, DR; Cameron, AA; Rabchevsky, AG; Randall, DC; Smith, GM1
Bove, GM; Devor, M; Stuart-Tilley, A; Weissner, W; Winterson, BJ1
Basbaum, AI; Mazarío, J1
Hughes, DI; Riddell, JS; Scott, DT; Todd, AJ1
Baumbauer, KM; Hoy, KC; Joynes, RL; Young, EE1
Dai, LY; Jiang, LS; Li, H; Liu, D; Zhao, CQ1
Blömer, U; Held-Feindt, J; Juraschek, M; Knerlich-Lukoschus, F; Lucius, R; Mehdorn, HM1
Bedard, PJ; Tremblay, LE1
Goldberger, ME; Murray, M; Zhang, B1
Cassam, AK; Llewellyn-Smith, IJ; Weaver, LC1
Kuo, HC1
Cassam, AK; Rogers, KA; Weaver, LC1
Jones, MG; Malcangio, M; McMahon, SB; Ramer, MS1
Klimaschewski, L1
Zhang, J1
Naftchi, NE1
Dey, PK; Nyberg, F; Olsson, Y; Sharma, HS1
Aanonsen, LM; Seybold, VS1
Faden, AI; Helke, CJ; Jacobs, TP1
Burnstock, G; Chilton, CP; Crowe, R; Light, K1

Reviews

1 review(s) available for substance p and Injuries, Spinal Cord

ArticleYear
Dysfunctions of regulatory neurotransmitters and neuropeptides following spinal cord injury.
    Annals of the New York Academy of Sciences, 1990, Volume: 579

    Topics: Animals; Cordotomy; Enkephalins; Morphine; Neuropeptides; Neurotransmitter Agents; Receptors, Opioid; Spinal Cord Injuries; Substance P

1990

Other Studies

39 other study(ies) available for substance p and Injuries, Spinal Cord

ArticleYear
Blocking SP/NK1R signaling improves spinal cord hemisection by inhibiting the release of pro-inflammatory cytokines in rabbits.
    The journal of spinal cord medicine, 2023, Volume: 46, Issue:5

    Topics: Animals; China; Cytokines; Interleukin-6; NF-kappa B; Rabbits; Spinal Cord; Spinal Cord Injuries; Substance P

2023
Substance P enhances endogenous neurogenesis to improve functional recovery after spinal cord injury.
    The international journal of biochemistry & cell biology, 2017, Volume: 89

    Topics: Animals; Cell Proliferation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Stem Cells; Neurogenesis; Neurons; Recovery of Function; Spinal Cord Injuries; Substance P

2017
Substance P as a mediator of neurogenic inflammation after balloon compression induced spinal cord injury.
    Journal of neurotrauma, 2013, Nov-01, Volume: 30, Issue:21

    Topics: Animals; Aquaporin 4; Capillary Permeability; Cerebrospinal Fluid Pressure; Disease Models, Animal; Edema; Neurogenic Inflammation; Rabbits; Recovery of Function; Spinal Cord Injuries; Substance P

2013
Substance P reduces apoptotic cell death possibly by modulating the immune response at the early stage after spinal cord injury.
    Neuroreport, 2013, Oct-23, Volume: 24, Issue:15

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cytokines; Inflammation; Male; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Substance P; Time Factors

2013
Changes in substance P and NK1 receptor immunohistochemistry following human spinal cord injury.
    Spinal cord, 2014, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Female; Humans; Immunohistochemistry; Male; Middle Aged; Receptors, Neurokinin-1; Spinal Cord Injuries; Substance P; Young Adult

2014
N-terminal truncations of substance P 1-7 amide affect its action on spinal cord injury-induced mechanical allodynia in rats.
    European journal of pharmacology, 2014, Sep-05, Volume: 738

    Topics: Amides; Amino Acid Sequence; Animals; Female; Hyperalgesia; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Structure-Activity Relationship; Substance P

2014
The effect of spinal cord injury on the neurochemical properties of vagal sensory neurons.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2015, Jun-15, Volume: 308, Issue:12

    Topics: Animals; Biomarkers; Disease Models, Animal; Glycoproteins; Immunohistochemistry; Lectins; Male; Neuronal Plasticity; Neurons, Afferent; Nodose Ganglion; Rats, Wistar; Receptors, Purinergic P2X3; Spinal Cord Injuries; Substance P; Urinary Bladder; Versicans

2015
Substance P stimulates proliferation of spinal neural stem cells in spinal cord injury via the mitogen-activated protein kinase signaling pathway.
    The spine journal : official journal of the North American Spine Society, 2015, Sep-01, Volume: 15, Issue:9

    Topics: Animals; Cell Proliferation; Cells, Cultured; MAP Kinase Signaling System; Neural Stem Cells; Rats; Spinal Cord Injuries; Stem Cell Transplantation; Substance P

2015
[The effects of sacral nerve root electrostimulation on the colon function and its mechanisms in a rat model of spinal cord injury].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2016, Volume: 32, Issue:1

    Topics: Animals; Colon; Electric Stimulation Therapy; Epithelial Cells; Intestinal Mucosa; Lumbosacral Region; Neurotransmitter Agents; Rats; Rats, Wistar; Spinal Cord Injuries; Substance P; Vasoactive Intestinal Peptide

2016
The spinal generator of ejaculation: Functional consequences of chronic spinalization and effect of substance P in anesthetized rats.
    Neuroscience, 2016, Nov-12, Volume: 336

    Topics: Animals; Ejaculation; Electric Stimulation; Electromyography; Male; Neurokinin-1 Receptor Antagonists; Neurons; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Substance P

2016
Substance P Promotes the Proliferation, but Inhibits Differentiation and Mineralization of Osteoblasts from Rats with Spinal Cord Injury via RANKL/OPG System.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Animals; Calcification, Physiologic; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Male; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Osteoprotegerin; Random Allocation; RANK Ligand; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord Injuries; Substance P; Up-Regulation

2016
The neonatal injury-induced spinal learning deficit in adult rats: central mechanisms.
    Behavioral neuroscience, 2008, Volume: 122, Issue:3

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Conditioning, Psychological; Exploratory Behavior; Female; Functional Laterality; Learning Disabilities; Pain Measurement; Pain Threshold; Physical Stimulation; Posterior Horn Cells; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Cord Injuries; Substance P; Time Factors

2008
Spatiotemporal CCR1, CCL3(MIP-1α), CXCR4, CXCL12(SDF-1α) expression patterns in a rat spinal cord injury model of posttraumatic neuropathic pain.
    Journal of neurosurgery. Spine, 2011, Volume: 14, Issue:5

    Topics: Animals; Biomarkers; Blotting, Western; Chemokine CCL3; Chemokine CXCL12; Disease Models, Animal; Immunohistochemistry; Male; Pain; Pain Threshold; Random Allocation; Rats; Receptors, Calcitonin Gene-Related Peptide; Receptors, CCR1; Receptors, CXCR4; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord Injuries; Substance P; TRPV Cation Channels

2011
[Observation of neuropeptides in bladder after spinal cord injury in rats].
    Zhonghua yi xue za zhi, 2012, Apr-17, Volume: 92, Issue:15

    Topics: Animals; Male; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Substance P; Urinary Bladder; Urinary Bladder, Neurogenic; Vasoactive Intestinal Peptide

2012
Substance P induces M2-type macrophages after spinal cord injury.
    Neuroreport, 2012, Sep-12, Volume: 23, Issue:13

    Topics: Animals; Anti-Inflammatory Agents; Axons; Cytokines; Inflammation; Interleukin-10; Macrophages; Male; Microglia; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Substance P; Tumor Necrosis Factor-alpha

2012
Sensory neuronal change after intravesical electrical stimulation in spinailized rat.
    Yonsei medical journal, 2002, Volume: 43, Issue:5

    Topics: Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; Ganglia, Spinal; Neurons, Afferent; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord Injuries; Substance P; Urination

2002
Involvement of peripherally released substance P and calcitonin gene-related peptide in mediating mechanical hyperalgesia in a traumatic neuropathy model of the rat.
    Neuroscience letters, 2004, Apr-29, Volume: 360, Issue:3

    Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Functional Laterality; Hyperalgesia; Lumbosacral Region; Male; Pain Measurement; Pain Threshold; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Rhizotomy; Spinal Cord Injuries; Statistics, Nonparametric; Substance P; Time Factors

2004
Spinal neurons involved in the generation of at-level pain following spinal injury in the rat.
    Neuroscience letters, 2004, May-06, Volume: 361, Issue:1-3

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Grooming; Immunohistochemistry; Immunotoxins; N-Glycosyl Hydrolases; Neurotoxins; Pain; Plant Proteins; Posterior Horn Cells; Rats; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Self Mutilation; Skin; Spinal Cord; Spinal Cord Injuries; Substance P

2004
[Changes in expression of SP in spinal lamina II following hemisected spinal cord injury in rats].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2005, Volume: 36, Issue:2

    Topics: Animals; Female; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Substance P; Time Factors

2005
Involvement of an increased spinal TRPV1 sensitization through its up-regulation in mechanical allodynia of CCI rats.
    Neuropharmacology, 2005, Volume: 49, Issue:7

    Topics: Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; In Vitro Techniques; Injections, Spinal; Male; Nerve Tissue Proteins; Neuropeptides; Pain; Pain Measurement; Physical Stimulation; Pyrazines; Pyridines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Substance P; TRPV Cation Channels; Up-Regulation

2005
Genetic manipulation of intraspinal plasticity after spinal cord injury alters the severity of autonomic dysreflexia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Mar-15, Volume: 26, Issue:11

    Topics: Adenoviridae; Afferent Pathways; Animals; Autonomic Dysreflexia; Autonomic Fibers, Preganglionic; Axons; Bradycardia; Calcitonin Gene-Related Peptide; Colon; Cordotomy; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Therapy; Genetic Vectors; Hypertension; Microinjections; Nerve Growth Factor; Neuronal Plasticity; Pain; Posterior Horn Cells; Rats; Rats, Wistar; Recombinant Fusion Proteins; Rectum; Semaphorin-3A; Spinal Cord Injuries; Substance P; Vasoconstriction

2006
Time course of substance P expression in dorsal root ganglia following complete spinal nerve transection.
    The Journal of comparative neurology, 2006, Jul-01, Volume: 497, Issue:1

    Topics: Animals; Cell Count; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Immunohistochemistry; Male; Neurons; Rats; Rats, Wistar; Spinal Cord Injuries; Substance P; Time Factors

2006
Contribution of substance P and neurokinin A to the differential injury-induced thermal and mechanical responsiveness of lamina I and V neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jan-24, Volume: 27, Issue:4

    Topics: Animals; Female; Hot Temperature; Male; Mice; Mice, Knockout; Neurokinin A; Pain; Pain Measurement; Physical Stimulation; Posterior Horn Cells; Spinal Cord Injuries; Substance P

2007
Upregulation of substance P in low-threshold myelinated afferents is not required for tactile allodynia in the chronic constriction injury and spinal nerve ligation models.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Feb-21, Volume: 27, Issue:8

    Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Constriction, Pathologic; Denervation; Disease Models, Animal; Electric Stimulation; Hyperesthesia; Ligation; Male; Medulla Oblongata; Nerve Fibers, Myelinated; Neurons, Afferent; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Sciatic Nerve; Sensory Thresholds; Spinal Cord; Spinal Cord Injuries; Spinal Nerves; Substance P; Time Factors; Up-Regulation

2007
Neurokinin receptors modulate the impact of uncontrollable stimulation on adaptive spinal plasticity.
    Behavioral neuroscience, 2007, Volume: 121, Issue:5

    Topics: Adaptation, Psychological; Animals; Electroshock; Female; Learning; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neuronal Plasticity; Pain; Peptide Fragments; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Spinal Cord; Spinal Cord Injuries; Substance P; Vocalization, Animal

2007
Changes of substance P-immunoreactive nerve fiber innervation density in the sublesional bones in young growing rats at an early stage after spinal cord injury.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2008, Volume: 19, Issue:4

    Topics: Animals; Bone Density; Male; Nerve Fibers; Neurotransmitter Agents; Osteoporosis; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Substance P; Treatment Outcome

2008
Force-dependent development of neuropathic central pain and time-related CCL2/CCR2 expression after graded spinal cord contusion injuries of the rat.
    Journal of neurotrauma, 2008, Volume: 25, Issue:5

    Topics: Animals; Calcitonin Gene-Related Peptide; Chemokine CCL2; Gene Expression; Hyperalgesia; Immunohistochemistry; Inflammation; Lumbosacral Region; Male; Motor Activity; Neuralgia; Pain Measurement; Rats; Rats, Inbred LEC; Receptors, CCR2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord Injuries; Substance P; Thoracic Vertebrae; Time; TRPV Cation Channels

2008
Action of 5-hydroxytryptamine, substance P, thyrotropin releasing hormone and clonidine on spinal neuron excitability.
    The journal of spinal cord medicine, 1995, Volume: 18, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Clonidine; Electromyography; Female; Motor Neurons; Muscle Spasticity; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Substance P; Synaptic Transmission; Thyrotropin-Releasing Hormone

1995
Proliferation of SP- and 5HT-containing terminals in lamina II of rat spinal cord following dorsal rhizotomy: quantitative EM-immunocytochemical studies.
    Experimental neurology, 1993, Volume: 123, Issue:1

    Topics: Animals; Cell Division; Denervation; Female; Immunohistochemistry; Microscopy, Electron; Nerve Endings; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Spinal Cord Injuries; Substance P

1993
Catecholamine enzymes and neuropeptides are expressed in fibres and somata in the intermediate gray matter in chronic spinal rats.
    Neuroscience, 1997, Volume: 78, Issue:3

    Topics: Animals; Autonomic Fibers, Preganglionic; Brain Chemistry; Catecholamines; Dopamine beta-Hydroxylase; Immunohistochemistry; Male; Nerve Fibers; Neurons; Neuropeptide Y; Neuropeptides; Rats; Rats, Wistar; Spinal Cord Injuries; Substance P

1997
Comparative study of the effects of capsaicin on the contractility of normal and spinal cord injured human bladders.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1997, Volume: 21, Issue:1

    Topics: Analgesics; Bethanechol; Capsaicin; Electric Stimulation; Humans; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Spinal Cord Injuries; Substance P; Urinary Bladder

1997
Co-localization of substance P and dopamine beta-hydroxylase with growth-associated protein-43 is lost caudal to a spinal cord transection.
    Neuroscience, 1999, Volume: 88, Issue:4

    Topics: Animals; Denervation; Dopamine beta-Hydroxylase; GAP-43 Protein; Immunohistochemistry; Male; Rats; Rats, Wistar; Reference Values; Spinal Cord; Spinal Cord Injuries; Substance P; Tissue Distribution

1999
Abnormal substance P release from the spinal cord following injury to primary sensory neurons.
    The European journal of neuroscience, 2000, Volume: 12, Issue:1

    Topics: Afferent Pathways; Animals; Axons; Axotomy; Nerve Fibers, Myelinated; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Spinal Cord Injuries; Spinal Nerve Roots; Spinal Nerves; Substance P; Time Factors

2000
Increased innervation of rat preganglionic sympathetic neurons by substance P containing nerve fibers in response to spinal cord injury.
    Neuroscience letters, 2001, Jul-13, Volume: 307, Issue:2

    Topics: Animals; Autonomic Dysreflexia; Autonomic Fibers, Preganglionic; Female; Immunohistochemistry; Nerve Regeneration; Neuronal Plasticity; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Substance P; Sympathetic Nervous System

2001
[The role of substance P in the modulation of myotension in paralyzed limbs after spinal transsection on rats].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1992, Volume: 14, Issue:6

    Topics: Animals; Capsaicin; Electromyography; Female; Injections, Spinal; Muscle Hypertonia; Muscle Tonus; Paraplegia; Rats; Rats, Wistar; Spinal Cord Injuries; Substance P

1992
Alteration of substance P after trauma to the spinal cord: an experimental study in the rat.
    Neuroscience, 1990, Volume: 38, Issue:1

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Fenclonine; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Spinal Cord Injuries; Substance P

1990
125I-substance P binding sites in rat spinal cord in a chronic constriction injury and following dorsal rhizotomy.
    Annals of the New York Academy of Sciences, 1991, Volume: 632

    Topics: Animals; Iodine Radioisotopes; Male; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Reference Values; Sciatic Nerve; Spinal Cord; Spinal Cord Injuries; Spinal Nerve Roots; Substance P; Time Factors

1991
Changes in substance P and somatostatin in the spinal cord after traumatic spinal injury in the rat.
    Neuropeptides, 1985, Volume: 6, Issue:3

    Topics: Animals; Male; Movement Disorders; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Spinal Cord Injuries; Substance P

1985
Vasoactive intestinal polypeptide-, somatostatin- and substance P-immunoreactive nerves in the smooth and striated muscle of the intrinsic external urethral sphincter of patients with spinal cord injury.
    The Journal of urology, 1986, Volume: 136, Issue:2

    Topics: Adolescent; Adult; Aged; Fluorescent Antibody Technique; Humans; Muscle, Smooth; Muscles; Nerve Fibers; Somatostatin; Spinal Cord Injuries; Substance P; Urethra; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Vasoactive Intestinal Peptide

1986