Page last updated: 2024-08-23

substance p and Fibrosis

substance p has been researched along with Fibrosis in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's2 (10.53)29.6817
2010's13 (68.42)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Block, M; Gharraee, N; Goslen, KH; Kavanagh, K; Lacy, JL; Levick, SP; Meléndez, GC; Whitfield, J; Widiapradja, A1
Guan, H; Jiang, X; Lan, HY; Li, J; Li, N; Liu, Y; Shu, X; Xia, Y; Zheng, Z; Zhong, M; Zhu, E1
Cao, Z; Li, X; Qing, L; Sui, X; Tang, J; Zhou, Z1
Danielson, P; Słoniecka, M1
Dong, F; Feng, YS; Wang, MM; Xing, Y; Zhang, F1
Guo, SW; Liu, X; Yan, D1
Hodges, PW; James, G; Klyne, DM; Millecamps, M; Stone, LS1
Agogo, GO; Guo, J; Peng, L; Yan, M1
Best, TM; Bowles, AC; Colombini, A; Correa, D; Kaplan, LD; Kouroupis, D; Perucca Orfei, C; Willman, MA1
Cassidy, MR; Gainsbury, ML; Gillespie, E; Heydrick, S; Kosaka, H; Sheldon, HK; Stucchi, AF1
Befus, AD; Hart, DA; Hildebrand, KA; Salo, PT; Zhang, M1
Condjella, RM; Conley, O; Dahl, MV; Fryer, AD; Jacoby, DB; Jacoby, NW; Kloeber, JA; Lee, JJ; Lee, NA; Luo, H; Maizer, P; Mazzolini, A; Neely, JL; Ochkur, SI; Patel, YS; Protheroe, CA; Raish, RJ; Scott, GD; Vega, ML; Zellner, KR1
Jung, KM; Jung, Y; Kim, JE; Kim, SH1
Baier, C; Beckmann, J; Grifka, J; Koeck, FX; Schmitt, M; Stangl, H; Straub, RH1
Guo, N; Li, B; Yang, Z; Zhang, X; Zhao, S1
Fazelbhoy, Z; Gerard, N; Hing, T; Karagiannides, I; Koon, HW; Lu, B; Pothoulakis, C; Shih, D; Xu, H; Zhao, D1
Carretero, OA; Cavasin, MA; Liao, TD; Yang, JJ; Yang, XP1
Katayama, I; Nishioka, K1
Goss, AN; Tahmasebi-Sarvestani, A; Tedman, R1

Reviews

2 review(s) available for substance p and Fibrosis

ArticleYear
Mechanisms involved in the arthrofibrosis formation and treatments following bone fracture.
    Journal of back and musculoskeletal rehabilitation, 2019, Volume: 32, Issue:6

    Topics: Angiogenesis Inhibitors; Bevacizumab; Bone Morphogenetic Protein 2; Debridement; Fibrosis; Fractures, Bone; Humans; Injections, Intra-Articular; Joints; Manipulation, Orthopedic; Mitogen-Activated Protein Kinase 1; Platelet-Derived Growth Factor; Risk Factors; Splints; Substance P; Tissue Adhesions; Transforming Growth Factor beta

2019
Substance P and fibrotic diseases.
    Neuropeptides, 2019, Volume: 76

    Topics: Animals; Corneal Diseases; Fibrosis; Heart Diseases; Humans; Inflammation; Joint Diseases; Kidney Diseases; Liver Cirrhosis; Primary Myelofibrosis; Substance P; Wound Healing

2019

Other Studies

17 other study(ies) available for substance p and Fibrosis

ArticleYear
Replacement substance P reduces cardiac fibrosis in monkeys with type 2 diabetes.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 160

    Topics: Animals; Cardiomyopathies; Chlorocebus aethiops; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Fibrosis; Mice; Myocardium; Stroke Volume; Substance P; Ventricular Function, Left

2023
Targeting NK-1R attenuates renal fibrosis
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Fibrosis; Inflammation; Kidney; Mice; Receptors, Neurokinin-1; Renal Insufficiency, Chronic; Substance P; Ureteral Obstruction

2023
Substance P promote macrophage M2 polarization to attenuate secondary lymphedema by regulating NF-kB/NLRP3 signaling pathway.
    Peptides, 2023, Volume: 168

    Topics: Animals; Endothelial Cells; Fibrosis; Humans; Lymphedema; Macrophages; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Substance P

2023
Substance P induces fibrotic changes through activation of the RhoA/ROCK pathway in an in vitro human corneal fibrosis model.
    Journal of molecular medicine (Berlin, Germany), 2019, Volume: 97, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Animals; Collagen; Corneal Keratocytes; Corneal Stroma; Enzyme Activation; Female; Fibroblasts; Fibrosis; Gene Expression; Humans; Male; Middle Aged; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Substance P

2019
The establishment of a mouse model of deep endometriosis.
    Human reproduction (Oxford, England), 2019, 02-01, Volume: 34, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Cell Transdifferentiation; Disease Models, Animal; Endometriosis; Endometrium; Epithelial-Mesenchymal Transition; Female; Fibrosis; Humans; Injections, Intraperitoneal; Mice; Myofibroblasts; Peritoneal Diseases; Peritoneum; Substance P

2019
ISSLS Prize in Basic science 2019: Physical activity attenuates fibrotic alterations to the multifidus muscle associated with intervertebral disc degeneration.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019, Volume: 28, Issue:5

    Topics: Animals; Collagen Type I; Collagen Type III; Connective Tissue; Connective Tissue Growth Factor; Disease Models, Animal; Fibronectins; Fibrosis; Gene Regulatory Networks; Intervertebral Disc Degeneration; Matrix Metalloproteinase 2; Mice, Knockout; Paraspinal Muscles; Physical Conditioning, Animal; Substance P; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

2019
Infrapatellar fat pad-derived MSC response to inflammation and fibrosis induces an immunomodulatory phenotype involving CD10-mediated Substance P degradation.
    Scientific reports, 2019, 07-26, Volume: 9, Issue:1

    Topics: Adipose Tissue; Adult; Animals; Bone Marrow Cells; Cells, Cultured; Connective Tissue Growth Factor; Cytokines; Disease Models, Animal; Female; Fibrosis; Healthy Volunteers; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Interferon-gamma; Male; Mesenchymal Stem Cells; Middle Aged; Neprilysin; Phenotype; Proteolysis; Rats; Rats, Sprague-Dawley; Substance P; Synovitis; Tumor Necrosis Factor-alpha

2019
The neurokinin 1 receptor regulates peritoneal fibrinolytic activity and postoperative adhesion formation.
    The Journal of surgical research, 2014, Volume: 191, Issue:1

    Topics: Animals; Ascitic Fluid; Bridged Bicyclo Compounds, Heterocyclic; Cecum; Female; Fibrosis; Laparotomy; Male; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Peritoneum; Receptors, Neurokinin-1; Substance P; Tissue Adhesions; Tissue Plasminogen Activator

2014
A myofibroblast-mast cell-neuropeptide axis of fibrosis in post-traumatic joint contractures: an in vitro analysis of mechanistic components.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014, Volume: 32, Issue:10

    Topics: Adult; Arm Injuries; Contracture; Elbow Injuries; Elbow Joint; Female; Fibrosis; Humans; Joint Capsule; Male; Mast Cells; Middle Aged; Myofibroblasts; Neuropeptides; Substance P

2014
Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice.
    The Journal of allergy and clinical immunology, 2015, Volume: 135, Issue:2

    Topics: Allergens; Animals; Cell Degranulation; Collagen; Dinitrofluorobenzene; Disease Models, Animal; Eosinophilia; Eosinophils; Fibrosis; Inflammation; Mice; Phthalic Anhydrides; Pruritus; Skin; Substance P

2015
Combined Treatment with Systemic and Local Delivery of Substance P Coupled with Self-Assembled Peptides for a Hind Limb Ischemia Model.
    Tissue engineering. Part A, 2016, Volume: 22, Issue:5-6

    Topics: Amino Acid Sequence; Animals; Apoptosis; Biocompatible Materials; Biomarkers; Cell Movement; Disease Models, Animal; Drug Delivery Systems; Endothelial Cells; Fibrosis; Fluorescent Antibody Technique; Hindlimb; Ischemia; Mesenchymal Stem Cells; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Neovascularization, Physiologic; Peptides; Rabbits; Substance P

2016
Predominance of synovial sensory nerve fibers in arthrofibrosis following total knee arthroplasty compared to osteoarthritis of the knee.
    Journal of orthopaedic surgery and research, 2016, Feb-17, Volume: 11

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Female; Fibrosis; Humans; Knee Joint; Male; Middle Aged; Nerve Fibers; Nociceptors; Osteoarthritis, Knee; Severity of Illness Index; Substance P; Synovial Membrane

2016
Substance P Inhibits the Collagen Synthesis of Rat Myocardial Fibroblasts Induced by Ang II.
    Medical science monitor : international medical journal of experimental and clinical research, 2016, Dec-16, Volume: 22

    Topics: Angiotensin II; Animals; Cells, Cultured; Collagen; Collagen Type I; Collagen Type III; Fibroblasts; Fibrosis; Heart; Myocardium; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Smad3 Protein; Substance P; Transforming Growth Factor beta; Transforming Growth Factor beta1

2016
Substance P modulates colitis-associated fibrosis.
    The American journal of pathology, 2010, Volume: 177, Issue:5

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Movement; Colitis; Collagen; Colon; Fibroblasts; Fibrosis; Humans; Insulin-Like Growth Factor I; Intestinal Mucosa; Mice; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Proto-Oncogene Proteins c-akt; Receptors, Neurokinin-1; Substance P; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Vimentin

2010
Decreased endogenous levels of Ac-SDKP promote organ fibrosis.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:1

    Topics: Angiotensin II; Animals; Arginine Vasopressin; Collagen; Fibrosis; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Kidney; Male; Myocardium; Oligopeptides; Prolyl Oligopeptidases; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Substance P; Time Factors

2007
Substance P augments fibrogenic cytokine-induced fibroblast proliferation: possible involvement of neuropeptide in tissue fibrosis.
    Journal of dermatological science, 1997, Volume: 15, Issue:3

    Topics: 3T3 Cells; Animals; Cell Division; Cell Line; Cytokines; Fibroblasts; Fibrosis; Histamine; Mast Cells; Mice; Mice, Inbred BALB C; Neuropeptides; Substance P

1997
The influence of experimentally induced osteoarthrosis on articular nerve fibers of the sheep temporomandibular joint.
    Journal of orofacial pain, 2001,Summer, Volume: 15, Issue:3

    Topics: Analysis of Variance; Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Cicatrix; Cysts; Disease Models, Animal; Fibrosis; Image Processing, Computer-Assisted; Immunohistochemistry; Joint Capsule; Male; Mandibular Condyle; Nerve Fibers; Nerve Tissue Proteins; Neurons, Afferent; Neuropeptide Y; Osteoarthritis; Sheep; Statistics, Nonparametric; Substance P; Synovial Membrane; Temporomandibular Joint; Temporomandibular Joint Disc; Temporomandibular Joint Disorders; Thiolester Hydrolases; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide

2001