substance p has been researched along with Eczema, Atopic in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.59) | 18.7374 |
| 1990's | 18 (28.57) | 18.2507 |
| 2000's | 24 (38.10) | 29.6817 |
| 2010's | 19 (30.16) | 24.3611 |
| 2020's | 1 (1.59) | 2.80 |
| Authors | Studies |
|---|---|
| Jaworek, AK; Jaworek, J; Szafraniec, K; Wojas-Pelc, A; Zuber, Z | 1 |
| Chai, R; He, S; Wang, J; Xie, H; Zhang, H; Zhang, Z; Zheng, W | 1 |
| Choi, H; Chung, E; Hong, HS; Hwang, JS; Kim, DJ; Lim, S; Nam, S; Park, KS; Shin, MK; Son, Y | 1 |
| Bradley, M; Hall, MA; Heilborn, J; Holmberg, J; Holst, M; Killasli, H; Lönndahl, L; Nordlind, K; Theodorsson, E | 1 |
| Choi, H; Chung, E; Hong, HS; Hwang, JS; Kim, DJ; Lim, S; Nam, S; Park, KS; Shin, MK; Son, Y; Won, Y | 1 |
| El-Nour, H; Holst, M; Johansson, B; Lönndahl, L; Lonne-Rahm, SB; Nordlind, K; Radu Djurfeldt, D; Rasul, A | 1 |
| Granstein, RD; Mehta, D | 1 |
| Fujita, S; Kasai, K; Shimizu, M; Utsunomiya, T; Yamaguchi, M; Yamamoto, H | 1 |
| Ahn, HK; Kim, HO; Lee, CH; Park, CW | 1 |
| Furue, M; Hosokawa, C; Takeuchi, S | 1 |
| Chikumoto, T; Igeta, K; Inagaki, N; Itoh, T; Katoh, H; Kim, JF; Nagai, H; Nagao, M; Shiraishi, N; Tanaka, H | 1 |
| Böhm, M; Capellino, S; Haas, S; Luger, TA; Phan, NQ; Ständer, S; Straub, RH | 1 |
| Nakagawa, H; Yano, C | 1 |
| Bae, BG; Lee, KH; Noh, JY; Oh, SH; Park, CO; Park, IH; Wu, WH | 1 |
| Hiramoto, K; Inoue, M; Inoue, R; Ishii, M; Kobayashi, H; Orita, K; Sato, EF | 1 |
| Alysandratos, KD; Angelidou, A; Asadi, S; Delivanis, DA; Kalogeromitros, D; Katsarou-Katsari, A; Leeman, SE; Miao, B; Miniati, A; Sismanopoulos, N; Theoharides, TC; Vasiadi, M; Weng, Z; Zhang, B | 1 |
| Bae, IH; Jang, WH; Koh, HJ; Lim, KM; Park, YH; Seo, JA; Yun, JW | 1 |
| El-Nour, H; Grip, L; Holst, M; Johansson, B; Lonne-Rahm, SB; Nordlind, K; Theodorsson, E | 1 |
| Akiyama, M; Bito, T; Hino, R; Kabashima, K; Kabashima-Kubo, R; Kobayashi, M; Mori, T; Nakamura, M; Nomura, T; Nomura, Y; Ogasawara, K; Sakabe, J; Shimizu, H; Sugita, K; Tokura, Y | 1 |
| Davoudi, SM; Panahi, Y; Ranjbar, R; Sahebkar, A; Taherzadeh, ES | 1 |
| Abd El-Latif, MI; Izumi, M; Katayama, I; Matsui, S; Murota, H; Nishioka, M; Sano, S; Tani, M; Terao, M | 1 |
| Köpnick, S; Neufang, G; Roggenkamp, D; Schmelz, M; Stäb, F; Wenck, H | 1 |
| Kimata, H | 5 |
| Harvima, IT; Järvikallio, A; Naukkarinen, A | 1 |
| Choi, HR; Chung, JH; Kim, KH; Park, KC | 1 |
| Aihara, M; Hosoi, J; Ikezawa, Z; Katsuno, M; Kojima, M; Matsuda, H; Nakamura, M; Osuna, H; Toyoda, M | 1 |
| Hayashi, T; Kadota, T; Kawachi, M; Konomi, A; Morikawa, M; Nanri, H; Ohmura, T; Satoh, H; Satoh, Y; Tsunenari, I | 1 |
| Hayashi, T; Jung, B; Konomi, A; Ohmura, T; Satoh, H; Satoh, Y | 1 |
| Izu, K; Tokura, Y | 1 |
| Hosogi, M; Ikoma, A; Miyachi, Y; Schmelz, M | 1 |
| Akiyama, H; Amano, H; Ishikawa, O; Negishi, I | 1 |
| Aki, T; Hashimoto, K; Hide, M; Kawamoto, S; Onishi, N; Ono, K; Santo, H; Shigeta, S; Suzuki, H | 1 |
| Hon, KL; Lam, MC; Leung, TF; Ng, PC; Wong, KY | 1 |
| Arck, PC; Daniltchenko, M; Hagen, E; Hunt, SP; Klapp, BF; Pavlovic, S; Peters, EM; Tobin, DJ | 1 |
| Baran, E; Salomon, J | 1 |
| Brodecka, H; Glinska-Ferenz, M; Glinski, W; Kowalski, D | 1 |
| Handwerker, HO; Heyer, G; Schmitz, J; Ulmer, FJ | 1 |
| Cremer, B; Czarnetzki, BM; Dippel, E; Heimann, A | 1 |
| DeMora, F; Ferrer, L; García, G; Puigdemont, A | 1 |
| Danno, K; Hirota, Y; Omoto, M; Sugiura, H; Uehara, M | 1 |
| Ayliffe, MJ; Gordon, DJ; Holden, CA; Ostlere, LS; Pereira, RS; Rustin, MH | 1 |
| Archer, CB; Kennedy, CT; Sabroe, RA | 1 |
| Gordon, DJ; Holden, CA; Ostlere, LS | 1 |
| Claudy, A; Doutremepuich, JD; Liebich, C; Misery, L; Odia, SG; Ring, J; Schmitt, D; Staniek, V; Vocks, E | 1 |
| Furukawa, F; Takigawa, M; Yagi, H; Yokote, R | 1 |
| Kagoura, M; Makino, T; Morohashi, M; Toyoda, M | 1 |
| Byun, DG; Kang, H; Kim, JW | 1 |
| Marsella, R; Nicklin, CF | 1 |
| Marsella, R; Melloy, C; Nicklin, CF | 1 |
| Hino, T; Kagoura, M; Makino, T; Morohashi, M; Nakamura, M; Toyoda, M | 1 |
| Cimitan, A; Fantini, F; Giannetti, A; Pincelli, C | 1 |
| Donatini, A; Fantini, F; Giannetti, A; Pincelli, C; Romualdi, P | 1 |
| Baart de la Faille, H; Nabarro, G; Schuurman, HJ; Tobin, D; van der Putte, SC; van Vloten, WA | 1 |
| Coulson, IH; Holden, CA | 1 |
| Fantini, F; Giannetti, A; Girolomoni, G; Massimi, P; Pincelli, C; Seidenari, S | 1 |
| Anand, P; Blank, MA; Bloom, SR; Polak, JM; Sellu, D; Springall, DR | 1 |
| Handwerker, HO; Heyer, G; Hornstein, OP | 1 |
| Shuster, S | 1 |
| Ahlstedt, S; Nilsson, G; Rak, S | 1 |
1 review(s) available for substance p and Eczema, Atopic
| Article | Year |
|---|---|
Immunoregulatory Effects of Neuropeptides on Endothelial Cells: Relevance to Dermatological Disorders.
Topics: Calcitonin Gene-Related Peptide; Cells, Cultured; Dermatitis, Atopic; Disease Progression; Endothelial Cells; Humans; Inflammation Mediators; Melanocyte-Stimulating Hormones; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Risk Assessment; Sensitivity and Specificity; Somatostatin; Substance P | 2019 |
7 trial(s) available for substance p and Eczema, Atopic
| Article | Year |
|---|---|
Substance P Antagonist Aprepitant Shows no Additive Effect Compared with Standardized Topical Treatment Alone in Patients with Atopic Dermatitis.
Topics: Administration, Cutaneous; Adult; Antipruritics; Aprepitant; Dermatitis, Atopic; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Pruritus; Severity of Illness Index; Skin; Substance P; Sweden; Time Factors; Treatment Outcome; Young Adult | 2018 |
Effects of tacrolimus ointment on the expression of substance P, nerve growth factor, and neurotrophin-3 in atopic dermatitis.
Topics: Administration, Topical; Adolescent; Adult; Biopsy; Child; Dermatitis, Atopic; Female; Humans; Immunosuppressive Agents; Male; Nerve Fibers; Nerve Growth Factor; Neurotrophin 3; Skin; Substance P; Tacrolimus; Young Adult | 2009 |
Severity scores, itch scores and plasma substance P levels in atopic dermatitis treated with standard topical therapy with oral olopatadine hydrochloride.
Topics: Administration, Oral; Administration, Topical; Adult; Dermatitis, Atopic; Dibenzoxepins; Drug Synergism; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Olopatadine Hydrochloride; Pruritus; Substance P; Young Adult | 2009 |
Suckling reduces allergic skin responses and plasma levels of neuropeptide and neurotrophin in lactating women with atopic eczema/dermatitis syndrome.
Topics: Adult; Antigens, Dermatophagoides; Dermatitis, Atopic; Female; Humans; Infant; Lactation; Nerve Growth Factor; Nerve Growth Factors; Neuropeptides; Pollen; Skin Tests; Substance P; Vasoactive Intestinal Peptide | 2003 |
The effects of topical doxepin on responses to histamine, substance P and prostaglandin E2 in human skin.
Topics: Administration, Topical; Adult; Antipruritics; Dermatitis, Atopic; Dinoprostone; Double-Blind Method; Doxepin; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Substance P; Terfenadine; Urticaria | 1997 |
The effects of capsaicin topical therapy in dogs with atopic dermatitis: a randomized, double-blinded, placebo-controlled, cross-over clinical trial.
Topics: Administration, Cutaneous; Animals; Capsaicin; Cross-Over Studies; Dermatitis, Atopic; Dog Diseases; Dogs; Double-Blind Method; Female; Male; Pruritus; Substance P; Treatment Outcome | 2002 |
Reactions to intradermally injected substance P and topically applied mustard oil in atopic dermatitis patients.
Topics: Acute Disease; Administration, Topical; Adolescent; Adult; Dermatitis, Atopic; Dose-Response Relationship, Drug; Drug Eruptions; Female; Humans; Injections, Intradermal; Male; Middle Aged; Mustard Plant; Pain; Plant Extracts; Plant Oils; Single-Blind Method; Substance P | 1991 |
55 other study(ies) available for substance p and Eczema, Atopic
| Article | Year |
|---|---|
Interleukin 25, thymic stromal lymphopoietin and house dust mites in pathogenesis of atopic dermatitis.
Topics: Adult; Aged; Allergens; Animals; Biomarkers; Cytokines; Dermatitis, Atopic; Female; Humans; Interleukin-17; Keratinocytes; Male; Middle Aged; Pyroglyphidae; Substance P; Young Adult | 2020 |
Up-regulated expression of substance P in CD8
Topics: Adolescent; Adult; Aged; Allergens; Animals; Case-Control Studies; CD8-Positive T-Lymphocytes; Dermatitis, Atopic; Flow Cytometry; Humans; Mice, Inbred BALB C; Middle Aged; Monocytes; Ovalbumin; Receptors, Neurokinin-1; Substance P; Up-Regulation; Young Adult | 2017 |
Manifestation of atopic dermatitis-like skin in TNCB-induced NC/Nga mice is ameliorated by topical treatment of substance P, possibly through blockade of allergic inflammation.
Topics: Administration, Cutaneous; Animals; CD3 Complex; Cell Degranulation; Cells, Cultured; Chemokine CCL17; Cytokines; Dermatitis, Atopic; Humans; Immunoglobulin E; Keratinocytes; Male; Mast Cells; Mice; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Picryl Chloride; Substance P; T-Lymphocytes; Thymic Stromal Lymphopoietin; Tumor Necrosis Factor-alpha | 2018 |
Substance P restores normal skin architecture and reduces epidermal infiltration of sensory nerve fiber in TNCB-induced atopic dermatitis-like lesions in NC/Nga mice.
Topics: Animals; Body Water; Cells, Cultured; Dermatitis, Atopic; Epidermis; Filaggrin Proteins; Male; Mice; Nerve Fibers; Nerve Growth Factor; Picryl Chloride; Pruritus; Semaphorin-3A; Skin; Substance P | 2018 |
Tachykinin upregulation in atopic dermatitis.
Topics: Adult; Biopsy; Cross-Sectional Studies; Dermatitis, Atopic; Female; Humans; Inflammation; Male; Middle Aged; Nerve Fibers; Neurokinin A; Receptors, Neurokinin-1; Skin; Substance P; Surveys and Questionnaires; Up-Regulation; Young Adult | 2019 |
Interleukin-17/T-helper 17 cells in an atopic dermatitis mouse model aggravate orthodontic root resorption in dental pulp.
Topics: Adolescent; Adult; Animals; CD4-Positive T-Lymphocytes; Cells, Cultured; Coculture Techniques; Dental Pulp; Dermatitis, Atopic; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin E; Interleukin-17; Interleukin-6; Interleukin-8; Male; Mice; Real-Time Polymerase Chain Reaction; Receptors, Interleukin-17; Root Resorption; Substance P; Th17 Cells; Tooth Movement Techniques | 2013 |
Depletion of substance P, a mechanism for inhibition of mouse scratching behavior by tacrolimus.
Topics: Animals; Behavior, Animal; Dermatitis, Atopic; Dexamethasone; Ear; Male; Mice; Mice, Inbred BALB C; Pruritus; Substance P; Tacrolimus | 2010 |
Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis.
Topics: Adrenergic Fibers; Adult; Aged; Aged, 80 and over; Biopsy; Chronic Disease; Dermatitis, Atopic; Dermis; Female; Fluorescent Antibody Technique; Humans; Male; Middle Aged; Prurigo; Pruritus; Sensory Receptor Cells; Substance P | 2010 |
[Substance P].
Topics: Dermatitis, Atopic; Humans; Immunoenzyme Techniques; Mood Disorders; Pain; Pneumonia, Aspiration; Substance P | 2010 |
Association of stress with symptoms of atopic dermatitis.
Topics: Adolescent; Adult; Anxiety; Biopsy; Case-Control Studies; Child; Depression; Dermatitis, Atopic; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nerve Growth Factor; Neuropeptide Y; Prognosis; Pruritus; Quality of Life; Receptors, Corticotropin-Releasing Hormone; Republic of Korea; Severity of Illness Index; Skin; Stress, Psychological; Substance P; Surveys and Questionnaires; Young Adult | 2010 |
Strong exercise stress exacerbates dermatitis in atopic model mice, NC/Nga mice, while proper exercise reduces it.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; beta-Endorphin; Dermatitis, Atopic; Exercise Test; Immunoglobulin E; Male; Mice; Mice, Inbred Strains; Physical Conditioning, Animal; Skin; Specific Pathogen-Free Organisms; Stress, Physiological; Substance P; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2010 |
Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: relevance to atopic dermatitis.
Topics: Adolescent; Adult; Antigens; Biological Transport, Active; Calcineurin; Calcium; Case-Control Studies; Cell Degranulation; Cells, Cultured; Child; Dermatitis, Atopic; Dynamins; Exocytosis; Female; GTP Phosphohydrolases; Humans; Immunoglobulin E; Male; Mast Cells; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Middle Aged; Mitochondria; Mitochondrial Proteins; RNA, Small Interfering; Substance P; Tumor Necrosis Factor-alpha; Young Adult | 2011 |
Antipruritic effects of TRPV1 antagonist in murine atopic dermatitis and itching models.
Topics: Acrylamides; Animals; Antipruritics; Dermatitis, Atopic; Dermatophagoides farinae; Disease Models, Animal; Male; Mice; p-Methoxy-N-methylphenethylamine; Pyridines; Substance P; Th2 Cells; TRPV Cation Channels | 2011 |
Substance P alterations in skin and brain of chronically stressed atopic-like mice.
Topics: Animals; Base Sequence; Brain; Chronic Disease; Dermatitis, Atopic; DNA Primers; Female; Immunohistochemistry; Mice; Polymerase Chain Reaction; Skin; Stress, Physiological; Substance P | 2013 |
A group of atopic dermatitis without IgE elevation or barrier impairment shows a high Th1 frequency: possible immunological state of the intrinsic type.
Topics: Adolescent; Adult; Biomarkers; Case-Control Studies; Chemokine CCL17; Child; Dermatitis, Atopic; DNA Mutational Analysis; Enzyme-Linked Immunosorbent Assay; Female; Filaggrin Proteins; Flow Cytometry; Humans; Immunoglobulin E; Immunohistochemistry; Interferon-gamma; Interleukin-18; Intermediate Filament Proteins; Japan; Male; Middle Aged; Mutation; Sensory Thresholds; Skin; Substance P; Th1 Cells; Th17 Cells; Th2 Cells; Up-Regulation; Water Loss, Insensible; Young Adult | 2012 |
Investigation of serum substance P status in patients with chronic pruritic skin lesions due to sulfur mustard: a cross-sectional study.
Topics: Adult; Cross-Sectional Studies; Dermatitis, Atopic; Humans; Iraq; Male; Middle Aged; Mustard Gas; Pruritus; Quality of Life; Substance P; Veterans | 2013 |
Artemin causes hypersensitivity to warm sensation, mimicking warmth-provoked pruritus in atopic dermatitis.
Topics: Animals; Cell Differentiation; Cell Proliferation; Dermatitis, Atopic; Female; Hot Temperature; Humans; Hyperalgesia; Hypersensitivity; Immunohistochemistry; Mice; Mice, Inbred C57BL; Nerve Growth Factor; Nerve Tissue Proteins; Neurites; Pruritus; Sensory Thresholds; Skin; Substance P; TRPV Cation Channels | 2012 |
Epidermal nerve fibers modulate keratinocyte growth via neuropeptide signaling in an innervated skin model.
Topics: Adult; Calcitonin Gene-Related Peptide; Cell Division; Cells, Cultured; Coculture Techniques; Dermatitis, Atopic; Dermis; Epidermal Cells; Epidermis; Fibroblasts; Ganglia, Spinal; Humans; Keratinocytes; Middle Aged; Neuropeptides; Organ Culture Techniques; Peripheral Nervous System; Receptor Activity-Modifying Protein 1; Receptors, Calcitonin Gene-Related Peptide; Repressor Proteins; RNA, Messenger; Substance P; Young Adult | 2013 |
Starvation reduces allergen-induced skin wheal responses and plasma substance P and vasoactive intestinal peptide in patients with atopic eczema/dermatitis syndrome.
Topics: Adult; Allergens; Animals; Case-Control Studies; Dermatitis, Atopic; Humans; Male; Skin; Skin Tests; Starvation; Substance P; Vasoactive Intestinal Peptide | 2002 |
Enhancement of allergic skin wheal responses by microwave radiation from mobile phones in patients with atopic eczema/dermatitis syndrome.
Topics: Adult; Allergens; Cell Phone; Dermatitis, Atopic; Female; Humans; Male; Microwaves; Middle Aged; Skin Tests; Substance P; Syndrome; Vasoactive Intestinal Peptide | 2002 |
Enhancement of allergic skin wheal responses and in vitro allergen-specific IgE production by computer-induced stress in patients with atopic dermatitis.
Topics: Adult; Computers; Dermatitis, Atopic; Female; Heart Rate; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Leukocytes, Mononuclear; Male; Skin; Stress, Psychological; Substance P; Vasoactive Intestinal Peptide | 2003 |
Mast cells, nerves and neuropeptides in atopic dermatitis and nummular eczema.
Topics: Adolescent; Adult; Calcitonin Gene-Related Peptide; Case-Control Studies; Cell Communication; Dermatitis, Atopic; Eczema; Female; Humans; Male; Mast Cells; Microscopy, Confocal; Middle Aged; Neurons, Afferent; Neuropeptides; Skin; Substance P; Vasoactive Intestinal Peptide | 2003 |
Enhancement of allergic skin wheal responses in patients with atopic eczema/dermatitis syndrome by playing video games or by a frequently ringing mobile phone.
Topics: Adult; Allergens; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Azulenes; Cell Phone; Cycloheptanes; Dermatitis, Atopic; Female; Humans; Immunoglobulin E; Male; Microwaves; Nerve Growth Factor; Piperazines; Skin Tests; Stress, Psychological; Substance P; Video Games | 2003 |
The effect of substance P on peripheral blood mononuclear cells in patients with atopic dermatitis.
Topics: Adult; Cell Division; Cells, Cultured; Cytokines; Dermatitis, Atopic; Female; Humans; Interferon-gamma; Interleukin-10; Male; Monocytes; Receptors, Neurokinin-1; Substance P; Tumor Necrosis Factor-alpha | 2003 |
Neuropeptides concentrations in the skin of a murine (NC/Nga mice) model of atopic dermatitis.
Topics: Animals; Back; Calcitonin Gene-Related Peptide; Dermatitis, Atopic; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunoglobulin E; Immunohistochemistry; Mice; Mice, Inbred Strains; Osmolar Concentration; Skin; Species Specificity; Staining and Labeling; Substance P | 2003 |
Role of substance P in an NC/Nga mouse model of atopic dermatitis-like disease.
Topics: Animals; Dermatitis, Atopic; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eosinophils; Immunoglobulin E; Immunohistochemistry; Interleukin-4; Male; Mast Cells; Mice; Picryl Chloride; Statistics, Nonparametric; Substance P | 2004 |
Involvement of substance P in scratching behaviour in an atopic dermatitis model.
Topics: Animals; Behavior, Animal; Dermatitis, Atopic; Disease Models, Animal; Male; Mice; Neurokinin-1 Receptor Antagonists; Pruritus; Receptors, Neurokinin-1; Substance P; Tachykinins | 2004 |
The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; E-Selectin; Female; Histamine H1 Antagonists; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Male; Olopatadine Hydrochloride; Substance P; Terfenadine; Vascular Cell Adhesion Molecule-1 | 2005 |
Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch.
Topics: Adult; Bradykinin; Cross-Over Studies; Dermatitis, Atopic; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Male; Pain; Pruritus; Serotonin; Single-Blind Method; Substance P; Urticaria; Water | 2006 |
Psychological stress can trigger atopic dermatitis in NC/Nga mice: an inhibitory effect of corticotropin-releasing factor.
Topics: Animals; Antibodies, Blocking; Corticosterone; Corticotropin-Releasing Hormone; Cytokines; Defecation; Dermatitis, Atopic; Immunoglobulin E; Immunohistochemistry; Lymph Nodes; Male; Mice; Pruritus; Stress, Psychological; Substance P; Water | 2008 |
Dietary pulverized konjac glucomannan suppresses scratching behavior and skin inflammatory immune responses in NC/Nga mice.
Topics: Animals; Dermatitis, Atopic; Dietary Carbohydrates; Disease Models, Animal; Ear; Eosinophilia; Immunoglobulin E; Immunoglobulin G; Interferon-alpha; Interleukin-10; Interleukin-4; Keratosis; Male; Mannans; Mastocytosis, Cutaneous; Mice; Mice, Inbred Strains; Pruritus; Skin; Substance P | 2007 |
Pathophysiology of nocturnal scratching in childhood atopic dermatitis: the role of brain-derived neurotrophic factor and substance P.
Topics: Brain-Derived Neurotrophic Factor; Chemokines; Child; Dermatitis, Atopic; Eosinophils; Female; Humans; Immunoglobulin E; Male; Pruritus; Quality of Life; Severity of Illness Index; Sleep; Substance P | 2007 |
Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice.
Topics: Animals; CD4 Lymphocyte Count; Cytokines; Dermatitis, Atopic; Female; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nerve Fibers; Neurogenic Inflammation; Receptors, Neurokinin-1; Skin; Stress, Psychological; Substance P; Th2 Cells | 2008 |
The role of selected neuropeptides in pathogenesis of atopic dermatitis.
Topics: Adolescent; Adult; Calcitonin Gene-Related Peptide; Case-Control Studies; Dermatitis, Atopic; Female; Humans; Immunoglobulin E; Inflammation; Male; Middle Aged; Neuropeptide Y; Pain Measurement; Pruritus; Severity of Illness Index; Skin; Substance P | 2008 |
Neuropeptides in psoriasis: possible role of beta-endorphin in the pathomechanism of the disease.
Topics: beta-Endorphin; Capsaicin; Dermatitis, Atopic; Humans; Neuropeptides; Psoriasis; Scleroderma, Systemic; Skin; Substance P | 1994 |
Histamine-induced itch and alloknesis (itchy skin) in atopic eczema patients and controls.
Topics: Administration, Cutaneous; Adolescent; Adult; Analysis of Variance; Cold Temperature; Dermatitis, Atopic; Female; Forearm; Histamine; Humans; Injections, Intradermal; Iontophoresis; Male; Middle Aged; Neurons, Afferent; Pruritus; Scapula; Skin; Skin Temperature; Substance P | 1995 |
Pruritogenic effects of mitogen-stimulated peripheral blood mononuclear cells in atopic eczema.
Topics: Adult; Cells, Cultured; Concanavalin A; Cytokines; Dermatitis, Atopic; Histamine; Humans; Leukocytes, Mononuclear; Mitogens; Phytohemagglutinins; Pruritus; Substance P | 1995 |
Effect of H1-antihistamines on histamine release from dispersed canine cutaneous mast cells.
Topics: Animals; Calcimycin; Cell Survival; Cetirizine; Concanavalin A; Dermatitis, Atopic; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Ketotifen; Loratadine; Mast Cells; Skin; Substance P; Terfenadine | 1997 |
Density and fine structure of peripheral nerves in various skin lesions of atopic dermatitis.
Topics: Adolescent; Adult; Dermatitis, Atopic; Humans; Immunohistochemistry; Keratinocytes; Microscopy, Electron; Nerve Endings; Nerve Fibers; Peripheral Nerves; Reference Values; Skin; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase | 1997 |
Substance P binding to peripheral blood mononuclear leukocytes in atopic dermatitis.
Topics: Adolescent; Adult; Dermatitis, Atopic; Female; Flow Cytometry; Fluorescein; Fluoresceins; Humans; Lymphocyte Subsets; Lymphocytes; Male; Middle Aged; Phycoerythrin; Protein Binding; Psoriasis; Substance P | 1997 |
Neuropeptide modulation of Th1 and Th2 cytokines in peripheral blood mononuclear leucocytes in atopic dermatitis and non-atopic controls.
Topics: Adult; Cell Culture Techniques; Dermatitis, Atopic; Dose-Response Relationship, Immunologic; Humans; Interferon-gamma; Interleukin-4; Leukocytes, Mononuclear; Substance P; Th1 Cells; Th2 Cells; Vasoactive Intestinal Peptide | 1997 |
Modulation of cutaneous SP receptors in atopic dermatitis after UVA irradiation.
Topics: Dermatitis, Atopic; Gene Expression Regulation; Humans; Keratinocytes; Receptors, Neurokinin-1; Substance P; Ultraviolet Therapy | 1998 |
Regulation of peripheral blood mononuclear cell responses to Dermatophagoides farinae by substance P in patients with atopic dermatitis.
Topics: Adolescent; Adult; Animals; Antigens, Dermatophagoides; Cell Division; Cytokines; Dermatitis, Atopic; Female; Gene Expression; Glycoproteins; Humans; Leukocytes, Mononuclear; Lymphocyte Count; Male; Middle Aged; Mites; RNA, Messenger; Substance P; T-Lymphocytes | 1998 |
Immunolocalization of substance P in human skin mast cells.
Topics: Adolescent; Adult; Dermatitis, Atopic; Female; Humans; Immunohistochemistry; Male; Mast Cells; Microscopy, Immunoelectron; Reference Values; Skin; Substance P | 2000 |
Effects of substance P and vasoactive intestinal peptide on interferon-gamma and interleukin-4 production in severe atopic dermatitis.
Topics: Adolescent; Adult; Dermatitis, Atopic; Female; Humans; Interferon-gamma; Interleukin-4; Male; Phytohemagglutinins; Substance P; Vasoactive Intestinal Peptide | 2000 |
Intradermal skin test reactivity to histamine and substance P is blunted in dogs with atopic dermatitis.
Topics: Animals; Case-Control Studies; Dermatitis, Atopic; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Histamine; Intradermal Tests; Male; Pruritus; Skin; Substance P; Time Factors | 2001 |
Nerve growth factor and substance P are useful plasma markers of disease activity in atopic dermatitis.
Topics: Adolescent; Adult; Biomarkers; Dermatitis, Atopic; Female; Humans; Male; Nerve Growth Factor; Severity of Illness Index; Substance P | 2002 |
Vasoactive intestinal polypeptide and substance P in the pathogenesis of atopic dermatitis.
Topics: Adolescent; Adult; Child; Chronic Disease; Dermatitis, Atopic; Female; Humans; Male; Peptide Fragments; Radioimmunoassay; Skin; Substance P; Vasoactive Intestinal Peptide | 1992 |
Substance P levels are decreased in lesional skin of atopic dermatitis.
Topics: Adolescent; Adult; Child; Dermatitis, Atopic; Female; Humans; Male; Radioimmunoassay; Reference Values; Skin; Substance P | 1992 |
Increased number of immunoreactive nerve fibers in atopic dermatitis.
Topics: Adolescent; Adult; Aged; Biopsy; Calcitonin Gene-Related Peptide; Child; Child, Preschool; Dermatitis, Atopic; Female; Humans; Immunohistochemistry; Infant; Intermediate Filaments; Lupus Erythematosus, Systemic; Male; Middle Aged; Nerve Fibers; Neurons, Afferent; Neuropeptides; Retrospective Studies; Skin; Substance P; Urticaria; Vasculitis | 1992 |
Cutaneous reactions to substance P and histamine in atopic dermatitis.
Topics: Adult; Dermatitis, Atopic; Dose-Response Relationship, Drug; Histamine; Humans; Mast Cells; Skin; Substance P; Time Factors | 1990 |
Neuropeptides in skin from patients with atopic dermatitis: an immunohistochemical study.
Topics: Adolescent; Adult; Aged; Calcitonin Gene-Related Peptide; Child; Dermatitis, Atopic; Female; Fluorescent Antibody Technique; Galanin; Humans; Male; Middle Aged; Neuropeptide Y; Neuropeptides; Peptides; Skin; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1990 |
Neuropeptides in skin disease: increased VIP in eczema and psoriasis but not axillary hyperhidrosis.
Topics: Adult; Axilla; Dermatitis, Atopic; Humans; Hyperhidrosis; Middle Aged; Psoriasis; Regional Blood Flow; Skin; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1991 |
Substance P antagonist and immune hypersensitivity reactions.
Topics: Dermatitis, Atopic; Humans; Substance P | 1991 |
The influence of substance P on the proliferation of peripheral blood lymphocytes from normal individuals and birch pollen-allergic patients.
Topics: Adult; Cells, Cultured; Concanavalin A; Dermatitis, Atopic; Humans; Lymphocyte Activation; Middle Aged; Plant Lectins; Pollen; Rhinitis, Allergic, Seasonal; Rosette Formation; Substance P | 1987 |