Page last updated: 2024-08-23

substance p and Diabetes Mellitus, Adult-Onset

substance p has been researched along with Diabetes Mellitus, Adult-Onset in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's8 (32.00)29.6817
2010's11 (44.00)24.3611
2020's5 (20.00)2.80

Authors

AuthorsStudies
Block, M; Gharraee, N; Goslen, KH; Kavanagh, K; Lacy, JL; Levick, SP; Meléndez, GC; Whitfield, J; Widiapradja, A1
Issar, T; Krishnan, AV; Kwai, N; Markoulli, M; Pisarcikova, J; Poynten, AM; Tummanapalli, SS; Willcox, MDP1
Cai, J; Fang, X; Gong, X; Ren, Y; Song, E1
Baek, SM; Hong, HS; Kim, K; Kim, S; Son, Y; Yu, SY1
Bhadada, SK; Malik, A; Morya, RK; Rana, SV; Saha, S; Singh, PK1
Park, KS; Um, J; Yu, J1
Duong, CL; Karras, J; Kim, J; Lum, E; Markoulli, M; Tolentino, JB; You, J1
Karamichos, D; Ma, JX; Priyadarsini, S; Rowsey, TG1
Choi, S; Jung, N; Kim, D; Lee, SH; Park, KS; Son, Y; Um, J1
Balemba, O; Gericke, M; Kappmeyer, AJ; Schmalz, JT; Stenkamp-Strahm, CM1
Balemba, OB; Gericke, M; Horton, S; Kappmeyer, AJ; Nyavor, YE; Stenkamp-Strahm, CM1
Albiero, M; Avogaro, A; Canal, F; Cappellari, R; Carnelli, F; Dang, Z; Emanueli, C; Fadini, GP; Falco, A; Furlan, A; Lorusso, B; Madeddu, P; Maselli, D; Ou, K; Paccagnella, A; Paiola, E; Quaini, F; Rodriguez-Arabaolaza, I; Rosa, F; Sambataro, M; Sangalli, E; Seganfreddo, E; Specchia, C; Spinetti, G1
Abdul, AM; Ackermann, PW; Ahmed, AS; Ahmed, M; Hart, DA; Hewitt, C; Li, J; Östenson, CG; Salo, PT1
Liu, Y; Qiu, GQ; Wang, R; Zhang, M; Zhao, XR1
Chikama, T; Chikamoto, N; Ishimitsu, T; Kamiya, A; Nishida, T; Yamada, N1
Fu, J; Li, G; Liu, B; Liu, L; Liu, P; Liu, X; Wu, B1
Byrd, JS; Elsayed, R; Marshall, GD; Minor, DS1
Bianchi, C; Chu, LM; Clements, RT; Dobrilovic, N; Feng, J; Fingleton, JG; Liu, Y; Sellke, FW; Singh, AK1
Chae, SL; Kim, JC; Lee, IG1
Galkowska, H; Karnafel, W; Olszewski, WL; Rosinski, G; Wojewodzka, U1
Furuta, T; Hishida, A; Ikuma, M; Iwasaki, H; Kajimura, M; Kanaoka, S; Osawa, S1
Fujimoto, K; Iwakiri, R1
Dhanasekaran, S; Mensah-Brown, E; Morrison, JF; Shaffiullah, M; Sheen, R; Shehab, S1
Grouzmann, E; Lacroix, JS; Landis, BN; Monod, M1
Dorsey, DA; Roth, KA; Schmidt, RE1

Trials

3 trial(s) available for substance p and Diabetes Mellitus, Adult-Onset

ArticleYear
Substance P induces sympathetic immune response in the contralateral eye after the first eye cataract surgery in type 2 diabetic patients.
    BMC ophthalmology, 2020, Aug-18, Volume: 20, Issue:1

    Topics: Aqueous Humor; Cataract; Cytokines; Diabetes Mellitus, Type 2; Humans; Immunity; Prospective Studies; Substance P; Vascular Endothelial Growth Factor A

2020
[Effect of Zhizhuwan on gastrointestinal peptide concentrations in plasma of diabetic gastroenteropathy with constipation patients].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:24

    Topics: Aged; Constipation; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Female; Gastrointestinal Diseases; Gastrointestinal Hormones; Gastrointestinal Motility; Humans; Male; Middle Aged; Substance P

2008
Efficacy of substance P and insulin-like growth factor-1 peptides for preventing postsurgical superficial punctate keratopathy in diabetic patients.
    Japanese journal of ophthalmology, 2009, Volume: 53, Issue:5

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Corneal Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Epithelium, Corneal; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Oligopeptides; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Substance P; Treatment Outcome

2009

Other Studies

22 other study(ies) available for substance p and Diabetes Mellitus, Adult-Onset

ArticleYear
Replacement substance P reduces cardiac fibrosis in monkeys with type 2 diabetes.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 160

    Topics: Animals; Cardiomyopathies; Chlorocebus aethiops; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Fibrosis; Mice; Myocardium; Stroke Volume; Substance P; Ventricular Function, Left

2023
A Comparative Study on the Diagnostic Utility of Corneal Confocal Microscopy and Tear Neuromediator Levels in Diabetic Peripheral Neuropathy.
    Current eye research, 2020, Volume: 45, Issue:8

    Topics: Adult; Area Under Curve; Calcitonin Gene-Related Peptide; Cornea; Corneal Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Microscopy, Confocal; Middle Aged; Prospective Studies; ROC Curve; Substance P; Tears; Trigeminal Nerve Diseases

2020
SP prevents T2DM complications by immunomodulation.
    Scientific reports, 2020, 10-07, Volume: 10, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Fatty Acids; Immunomodulation; Insulin Resistance; Male; Rats; Rats, Inbred OLETF; Substance P; Triglycerides

2020
Angiotensin-Converting Enzyme Gene Polymorphism Influences Gastrointestinal Motility in Type 2 Diabetes Mellitus.
    Biochemical genetics, 2021, Volume: 59, Issue:1

    Topics: Alleles; Angiotensins; Diabetes Mellitus, Type 2; Female; Gastrointestinal Motility; Gene Frequency; Genotype; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Substance P

2021
Substance P accelerates wound healing in type 2 diabetic mice through endothelial progenitor cell mobilization and Yes-associated protein activation.
    Molecular medicine reports, 2017, Volume: 15, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Animals; Bone Marrow; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Progenitor Cells; Immunohistochemistry; Injections, Subcutaneous; Male; Mice; Neovascularization, Physiologic; Phosphoproteins; Platelet Endothelial Cell Adhesion Molecule-1; Random Allocation; Substance P; Wound Healing; YAP-Signaling Proteins

2017
Corneal Nerve Morphology and Tear Film Substance P in Diabetes.
    Optometry and vision science : official publication of the American Academy of Optometry, 2017, Volume: 94, Issue:7

    Topics: Case-Control Studies; Cornea; Corneal Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Eye Proteins; Female; Humans; Male; Microscopy, Confocal; Middle Aged; Nerve Fibers; Prospective Studies; Substance P; Tears; Trigeminal Nerve; Trigeminal Nerve Diseases

2017
Unravelling the stromal-nerve interactions in the human diabetic cornea.
    Experimental eye research, 2017, Volume: 164

    Topics: Biomarkers; Case-Control Studies; Cell Differentiation; Cells, Cultured; Coculture Techniques; Collagen; Corneal Diseases; Corneal Stroma; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Extracellular Matrix; Female; Fibroblasts; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Models, Biological; Neurons; Receptor, IGF Type 1; Substance P; Tubulin

2017
Substance P preserves pancreatic β-cells in type 1 and type 2 diabetic mice.
    Biochemical and biophysical research communications, 2018, 05-23, Volume: 499, Issue:4

    Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Hyperglycemia; Immunomodulation; Insulin-Secreting Cells; Male; Mice, Inbred NOD; Pancreatic Stellate Cells; Substance P

2018
High-fat diet ingestion correlates with neuropathy in the duodenum myenteric plexus of obese mice with symptoms of type 2 diabetes.
    Cell and tissue research, 2013, Volume: 354, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Duodenum; Mice; Mice, Inbred C57BL; Mice, Obese; Myenteric Plexus; Neurons; Nitric Oxide Synthase; Obesity; Substance P; Vasoactive Intestinal Peptide

2013
Prolonged high fat diet ingestion, obesity, and type 2 diabetes symptoms correlate with phenotypic plasticity in myenteric neurons and nerve damage in the mouse duodenum.
    Cell and tissue research, 2015, Volume: 361, Issue:2

    Topics: Animals; Apoptosis; Diabetes Mellitus, Type 2; Diet, High-Fat; Duodenum; Enteric Nervous System; Insulin Resistance; Mice; Mice, Inbred C57BL; Myenteric Plexus; Neurodegenerative Diseases; Neurons; Nitric Oxide Synthase; Obesity; Substance P

2015
Sensory neuropathy hampers nociception-mediated bone marrow stem cell release in mice and patients with diabetes.
    Diabetologia, 2015, Volume: 58, Issue:11

    Topics: Animals; Cross-Sectional Studies; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Hematopoietic Stem Cells; Humans; Mice; Nociception; Sensory Receptor Cells; Substance P

2015
Compromised Neurotrophic and Angiogenic Regenerative Capability during Tendon Healing in a Rat Model of Type-II Diabetes.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Achilles Tendon; Animals; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression; Male; Neovascularization, Physiologic; Nerve Growth Factor; Rats; Rats, Wistar; Receptor, trkA; Receptor, trkB; Receptors, Neurokinin-1; Substance P; Tendon Injuries; Wound Healing

2017
Substance P is associated with the development of obesity, chronic inflammation and type 2 diabetes mellitus.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2011, Volume: 119, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Interleukin-6; Male; Middle Aged; Obesity; Substance P; Triglycerides; Uric Acid

2011
DPP-4 inhibitors and angioedema: a cause for concern?
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2011, Volume: 106, Issue:5

    Topics: Angioedema; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypertension; Product Surveillance, Postmarketing; Substance P

2011
Changes in microvascular reactivity after cardiopulmonary bypass in patients with poorly controlled versus controlled diabetes.
    Circulation, 2012, Sep-11, Volume: 126, Issue:11 Suppl 1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aged; Arterioles; Cardiopulmonary Bypass; Coronary Artery Bypass; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Disease Susceptibility; Endothelium, Vascular; Enzyme Induction; Female; Gene Expression Regulation; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Male; Microcirculation; Middle Aged; Muscle, Skeletal; Nitroprusside; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Substance P; Tyrosine; Vasoconstriction; Vasodilator Agents

2012
Involvement of circulating endothelial progenitor cells and vasculogenic factors in the pathogenesis of diabetic retinopathy.
    Eye (London, England), 2006, Volume: 20, Issue:5

    Topics: Aged; Aged, 80 and over; Angiogenesis Inducing Agents; Antigens, CD34; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelium, Vascular; Erythropoietin; Female; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Retinal Neovascularization; Severity of Illness Index; Stem Cells; Substance P; Vascular Endothelial Growth Factor A

2006
Neurogenic factors in the impaired healing of diabetic foot ulcers.
    The Journal of surgical research, 2006, Volume: 134, Issue:2

    Topics: Aged; Calcitonin Gene-Related Peptide; Diabetes Mellitus, Type 2; Diabetic Foot; Epidermis; Female; GAP-43 Protein; Humans; Immunohistochemistry; Inflammation; Male; Middle Aged; Nerve Endings; Neurotrophin 3; Skin; Substance P; Ubiquitin Thiolesterase

2006
A deficiency of gastric interstitial cells of Cajal accompanied by decreased expression of neuronal nitric oxide synthase and substance P in patients with type 2 diabetes mellitus.
    Journal of gastroenterology, 2006, Volume: 41, Issue:11

    Topics: Biomarkers; Cell Count; Diabetes Mellitus, Type 2; Female; Gastric Emptying; Gastric Mucosa; Humans; Immunohistochemistry; Male; Microscopy, Confocal; Myenteric Plexus; Neurons; Nitric Oxide Synthase Type I; Retrospective Studies; Substance P

2006
Diabetic gastropathy and interstitial cells of Cajal: a clue for bringing understanding out of chaos?
    Journal of gastroenterology, 2006, Volume: 41, Issue:11

    Topics: Biomarkers; Cell Count; Diabetes Mellitus, Type 2; Gastric Mucosa; Humans; Immunohistochemistry; Microscopy, Confocal; Myenteric Plexus; Neurons; Nitric Oxide Synthase Type I; Substance P

2006
Sensory and autonomic nerve changes in the monosodium glutamate-treated rat: a model of type II diabetes.
    Experimental physiology, 2008, Volume: 93, Issue:2

    Topics: Aging; Animals; Autonomic Nervous System; Blood Glucose; Body Weight; Calcitonin Gene-Related Peptide; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Glucose Intolerance; Glucose Tolerance Test; Hot Temperature; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Neurons, Afferent; Obesity; Organ Size; Pain Measurement; Physical Stimulation; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Neurokinin-1; Sodium Glutamate; Substance P

2008
Adverse effects of incretin therapy for type 2 diabetes.
    JAMA, 2007, Oct-17, Volume: 298, Issue:15

    Topics: Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Inflammation; Nasopharyngitis; Substance P

2007
Immunohistochemical characterization of NPY and substance P containing nerve terminals in aged and diabetic human sympathetic ganglia.
    Brain research, 1992, Jun-26, Volume: 583, Issue:1-2

    Topics: Aged; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ganglia, Sympathetic; Humans; Immunohistochemistry; Nerve Endings; Neurons; Neuropeptide Y; Substance P

1992