Page last updated: 2024-08-23

substance p and Depression, Involutional

substance p has been researched along with Depression, Involutional in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's17 (80.95)29.6817
2010's2 (9.52)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Hattori, K; Hidese, S; Ishida, I; Kunugi, H; Matsuo, J; Yoshida, F1
Cho, SH; Choi, S; Ham, BJ; Han, KM; Joe, SH; Kang, J; Kim, A; Kim, YK; Lee, MS; Tae, WS; Won, E; Yoon, HK1
Christie, IC; Cizza, G; Eskandari, F; Marques, AH; Phillips, TM; Silverman, MN; Sternberg, EM; Torvik, S1
Amoruso, A; Bardelli, C; Brunelleschi, S; Fresu, LG; Manzetti, E; Valsesia, R; Zeppegno, P1
Blier, P; Friedman, L; Jurjus, G; Konick, L; Meltzer, HY; Overholser, JC; Rajkowska, G; Shi, X; Stockmeier, CA1
Nemeroff, CB1
Holsboer, F1
Baghai, TC; Bondy, B; Minov, C; Möller, HJ; Rupprecht, R; Schüle, C; Schwarz, MJ; Zwanzger, P1
Blier, P; Gobbi, G; Haddjeri, N; Hen, R; Mathew, G; Santarelli, L1
Berger, M; Fiebich, BL; Grunze, H; Lieb, K; Normann, C; Walden, J1
Bartfai, T; Fetissov, S; Gaudet, L; Hökfelt, T; Jimenez, PA; Mathé, AA; Moreau, JL; Mortas, P; Sergeyev, V1
Claes, S; Del-Favero, J; Massat, I; Mendlewicz, J; Oswald, P; Souery, D; Van Broeckhoven, C1
Deuschle, M; Fiebich, BL; Herpfer, I; Heuser, I; Lieb, K; Sander, P1
Ball, W; Beebe, K; Hargreaves, R; Hietala, J; Keller, M; Lines, C; Liu, G; Montgomery, S; Morrison, M; Reines, S; Snavely, D1
Baker, K; Berger, A; Bolle, J; Calis, KA; Cizza, G; Handel, D; Hartman, JM; Mannes, A; Pereira, D; Phillips, TM; Ronsaville, D; Sonbolian, N; St Germain, D; Torvik, S1
Baker, DG; Carpenter, LL; Ekhator, NN; Geracioti, TD; Horn, PS; Kinkead, B; Nemeroff, CB; Owens, MJ; Price, LH; Sanacora, G; Strawn, JR1
Norman, TR1
Benton, T; Douglas, SD; Dubé, B; Evans, DL; Gettes, DR; Lai, JP; Lynch, KG; Metzger, D; Tustin, NB1
Bayat, L; Carpenter, LL; Kinkead, B; Kling, MA; Moreno, F; Nemeroff, CB; Owens, MJ; Price, LH; Tyrka, AR1
Bonaccorso, S; Delmeire, L; Goossens, F; Lin, AH; Maes, M; Pioli, R; Scharpé, S; Van Gastel, A1
Kramer, MS1

Reviews

4 review(s) available for substance p and Depression, Involutional

ArticleYear
Recent advances in the neurobiology of depression.
    Psychopharmacology bulletin, 2002,Summer, Volume: 36 Suppl 2

    Topics: Antidepressive Agents; Depressive Disorder, Major; Humans; Norepinephrine; Pyrimidines; Receptors, Corticotropin-Releasing Hormone; Serotonin; Substance P

2002
Antidepressant drug discovery in the postgenomic era.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2001, Volume: 2, Issue:4

    Topics: Adrenocorticotropic Hormone; Antidepressive Agents; Corticotropin-Releasing Hormone; Depressive Disorder, Major; Gene Expression; Genotype; Humans; Muscle, Smooth; Neuropeptides; Substance P

2001
Prospects for the treatment of depression.
    The Australian and New Zealand journal of psychiatry, 2006, Volume: 40, Issue:5

    Topics: Acetamides; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Hypnotics and Sedatives; Nerve Growth Factors; Selective Serotonin Reuptake Inhibitors; Substance P; Thiophenes; Vasopressins

2006
Update on Substance P (NK-1 receptor) antagonists in clinical trials for depression.
    Neuropeptides, 2000, Volume: 34, Issue:5

    Topics: Animals; Clinical Trials as Topic; Depressive Disorder, Major; Humans; Neurokinin-1 Receptor Antagonists; Substance P

2000

Trials

7 trial(s) available for substance p and Depression, Involutional

ArticleYear
Elevated neuroimmune biomarkers in sweat patches and plasma of premenopausal women with major depressive disorder in remission: the POWER study.
    Biological psychiatry, 2008, Nov-15, Volume: 64, Issue:10

    Topics: Adult; Biomarkers; Calcitonin Gene-Related Peptide; Case-Control Studies; Catecholamines; Chromatography, Affinity; Cytokines; Depressive Disorder, Major; Female; Humans; Hydrocortisone; Longitudinal Studies; Neuropeptide Y; Premenopause; Substance P; Sweat; Young Adult

2008
Substance P serum levels are increased in major depression: preliminary results.
    Biological psychiatry, 2003, Mar-15, Volume: 53, Issue:6

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Substance P; Time Factors

2003
Serum levels of substance P and response to antidepressant pharmacotherapy.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:5

    Topics: Acute Disease; Adult; Antidepressive Agents; Depressive Disorder, Major; Humans; Lamotrigine; Paroxetine; Severity of Illness Index; Substance P; Surveys and Questionnaires; Triazines

2004
Substance P in serum and cerebrospinal fluid of depressed patients: no effect of antidepressant treatment.
    Psychiatry research, 2005, Jul-15, Volume: 136, Issue:1

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychometrics; Receptors, Neurokinin-1; Severity of Illness Index; Substance P

2005
Lack of efficacy of the substance p (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder.
    Biological psychiatry, 2006, Feb-01, Volume: 59, Issue:3

    Topics: Adult; Antidepressive Agents; Aprepitant; Brain; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Personality Inventory; Positron-Emission Tomography; Reproducibility of Results; Substance P; Treatment Outcome

2006
Quality of life and pain in premenopausal women with major depressive disorder: the POWER Study.
    Health and quality of life outcomes, 2006, Jan-18, Volume: 4

    Topics: Adult; Alendronate; Bone Density; Bone Density Conservation Agents; Calcitonin Gene-Related Peptide; Case-Control Studies; Depressive Disorder, Major; Female; Humans; Longitudinal Studies; Middle Aged; Pain; Pain Measurement; Premenopause; Quality of Life; Stress, Psychological; Substance P

2006
Selective serotonin reuptake inhibitor and substance P antagonist enhancement of natural killer cell innate immunity in human immunodeficiency virus/acquired immunodeficiency syndrome.
    Biological psychiatry, 2008, May-01, Volume: 63, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; Biphenyl Compounds; Citalopram; Depressive Disorder; Depressive Disorder, Major; Female; Glucocorticoids; HIV Seropositivity; Hormone Antagonists; Humans; Immunity, Innate; Killer Cells, Natural; Lymphocyte Count; Middle Aged; Mifepristone; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Substance P; T-Lymphocytes, Cytotoxic; Viral Load

2008

Other Studies

10 other study(ies) available for substance p and Depression, Involutional

ArticleYear
Plasma neuropeptide levels in patients with schizophrenia, bipolar disorder, or major depressive disorder and healthy controls: A multiplex immunoassay study.
    Neuropsychopharmacology reports, 2023, Volume: 43, Issue:1

    Topics: alpha-MSH; beta-Endorphin; Bipolar Disorder; Depressive Disorder, Major; Humans; Immunoassay; Neurotensin; Oxytocin; Schizophrenia; Substance P

2023
The association between substance P and white matter integrity in medication-naive patients with major depressive disorder.
    Scientific reports, 2017, 08-29, Volume: 7, Issue:1

    Topics: Adult; Biomarkers; Case-Control Studies; Depressive Disorder, Major; Diffusion Tensor Imaging; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Substance P; White Matter

2017
Recurrent major depressive disorder: Imbalance of neurokinin (NK)-1 and NK-2 receptor expression in monocytes.
    Pharmacological research, 2013, Volume: 68, Issue:1

    Topics: Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Monocytes; Neurokinin A; Neurotransmitter Agents; NF-kappa B; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tumor Necrosis Factor-alpha

2013
Neurokinin-1 receptors are decreased in major depressive disorder.
    Neuroreport, 2002, Jul-02, Volume: 13, Issue:9

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Binding Sites; Binding, Competitive; Brain Chemistry; Depressive Disorder, Major; Down-Regulation; Female; Humans; Male; Middle Aged; Neurokinin-1 Receptor Antagonists; Neurons; Prefrontal Cortex; Radioligand Assay; Receptors, Neurokinin-1; Substance P; Suicide

2002
Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response.
    Journal of psychiatry & neuroscience : JPN, 2004, Volume: 29, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Antiemetics; Anxiety; Aprepitant; Autoreceptors; Depressive Disorder, Major; Electrophysiology; Hippocampus; Locus Coeruleus; Mice; Mice, Mutant Strains; Morpholines; Neurokinin-1 Receptor Antagonists; Norepinephrine; Phenylephrine; Photomicrography; Raphe Nuclei; Receptors, Neurokinin-1; Serotonin; Substance P

2004
Neuropeptide expression in rats exposed to chronic mild stresses.
    Psychopharmacology, 2005, Volume: 178, Issue:2-3

    Topics: Amygdala; Animals; Arcuate Nucleus of Hypothalamus; Brain; Brain Mapping; Chronic Disease; Dentate Gyrus; Depressive Disorder, Major; Disease Models, Animal; Galanin; Gene Expression Regulation; Hypothalamus; Male; Neuropeptide Y; Neuropeptides; Rats; Rats, Wistar; RNA, Messenger; Self Stimulation; Stress, Psychological; Substance P

2005
Patient-control association study of substance P-related genes in unipolar and bipolar affective disorders.
    The international journal of neuropsychopharmacology, 2005, Volume: 8, Issue:4

    Topics: Adult; Aged; Alleles; Belgium; Bipolar Disorder; Depressive Disorder, Major; Female; Gene Frequency; Genotype; Haplotypes; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Substance P

2005
Elevated cerebrospinal fluid substance p concentrations in posttraumatic stress disorder and major depression.
    The American journal of psychiatry, 2006, Volume: 163, Issue:4

    Topics: Acute Disease; Adult; Arousal; Catheters, Indwelling; Combat Disorders; Cross-Over Studies; Depressive Disorder, Major; Humans; Life Change Events; Male; Periodicity; Photic Stimulation; Spinal Puncture; Stress Disorders, Post-Traumatic; Stress, Psychological; Subarachnoid Space; Substance P; Videotape Recording; Visual Perception

2006
Decreased cerebrospinal fluid concentrations of substance P in treatment-resistant depression and lack of alteration after acute adjunct vagus nerve stimulation therapy.
    Psychiatry research, 2008, Jan-15, Volume: 157, Issue:1-3

    Topics: Adult; Combined Modality Therapy; Depressive Disorder, Major; Drug Resistance; Electric Stimulation Therapy; Female; Humans; Male; Periodicity; Substance P; Vagus Nerve

2008
Higher serum prolyl endopeptidase activity in patients with post-traumatic stress disorder.
    Journal of affective disorders, 1999, Volume: 53, Issue:1

    Topics: Adult; Arginine Vasopressin; Depressive Disorder, Major; Endopeptidases; Female; Fluorometry; Humans; Male; Middle Aged; Neurotensin; Oxytocin; Reinforcement, Psychology; Severity of Illness Index; Stress Disorders, Post-Traumatic; Substance P; Thyrotropin-Releasing Hormone

1999