Page last updated: 2024-08-23

substance p and Cystitis

substance p has been researched along with Cystitis in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (24.14)18.2507
2000's16 (55.17)29.6817
2010's6 (20.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chuang, YC; Lee, WC; Su, CH; Tain, YL; Tsai, CN; Yu, CC1
Arms, L; Dugan, C; Malley, S; May, V; Vizzard, MA1
Daniel, M; Gonzalez, EJ; Kosofsky, M; Lambert, D; Malley, S; Peterson, A; Vizzard, MA1
Birder, LA; Braas, KM; Girard, BM; May, V; Vizzard, MA; Wolf-Johnston, A1
DeBerry, J; Ness, TJ; Randich, A; Robbins, MT; Shaffer, AD1
Ball, CL; Ness, TJ; Randich, A; Robbins, MT; Shaffer, AD1
Girard, BM; May, V; Parsons, RL; Tompkins, JD; Vizzard, MA1
DeBoer, DJ; Gerard, NP; Nguyen, NB; Saban, MR; Saban, R; Wershil, BK1
Centola, M; Dozmorov, I; Knowlton, N; Saban, MR; Saban, R1
Duffy, RA1
Meyer-Siegler, KL; Vera, PL2
Chancellor, MB; de Groat, WC; Erickson, KA; Igawa, Y; Nishizawa, O; Ogawa, T; Seki, M; Seki, S; Yoshimura, N1
Bucala, R; Iczkowski, KA; Leng, L; Meyer-Siegler, KL; Vera, PL1
Alfieri, AB; Linares-Fernández, BE1
Andrade-Gordon, P; D'Andrea, MR; Derian, CK; Dozmorov, I; Hurst, RE; Ihnat, MA; Saban, MR; Saban, R; Simpson, C1
Andrade-Gordon, P; D'Andrea, MR; Davis, CA; Derian, CK; Dozmorov, I; Hurst, RE; Ihnat, MA; Saban, MR; Saban, R; Simpson, C1
Christmas, TJ; Frenz, AM; Pearce, FL1
Kream, RM; Marchand, J; Pang, X; Sant, GR; Theoharides, TC1
Giuliani, S; Lecci, A; Lippe, IT; Maggi, CA; Santicioli, P1
Bjorling, DE; Saban, MR; Saban, R1
Austin-Ritchie, T; Baker, S; Carraway, RE; Hollins, C; Luber-Narod, J; Malhotra, RK; Menon, M1
Bjorling, DE; Busser, BW; Jerde, TJ; Saban, MR; Saban, R; Zine, MJ1
Bjorling, DE; Bost, KL; Campbell, WC; Goda, FO; Hammond, TG; Harris, HW; Kaysen, JH; Lewis, FC; Navar, GL; Saban, M; Saban, R; Wang, XC; Zeidel, ML1
Cervero, F; De Felipe, C; Hunt, SP; Laird, JM; Olivar, T; Roza, C1
Saban, R1
Bjorling, DE; Haak-Frendscho, M; Hammond, TG; Saban, MR; Saban, R; Steinberg, H; Tengowski, MW1
Hammond, TG; Nguyen, NB; Saban, MR; Saban, R1
Fukuoka, M; Gomi, Y; Ito, Y; Kakiuchi, M; Kato, H; Morikawa, K1

Reviews

1 review(s) available for substance p and Cystitis

ArticleYear
Potential therapeutic targets for neurokinin-1 receptor antagonists.
    Expert opinion on emerging drugs, 2004, Volume: 9, Issue:1

    Topics: Analgesics; Anti-Anxiety Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antiemetics; Antineoplastic Agents; Antitussive Agents; Anxiety; Asthma; Clinical Trials as Topic; Cough; Cystitis; Depression; Drug Design; Humans; Inflammation; Irritable Bowel Syndrome; Neoplasms; Neurokinin-1 Receptor Antagonists; Pain; Substance P; Vomiting

2004

Other Studies

28 other study(ies) available for substance p and Cystitis

ArticleYear
Ba-Wei-Die-Huang-Wan (Hachimi-jio-gan) can ameliorate ketamine-induced cystitis by modulating neuroreceptors, inflammatory mediators, and fibrogenesis in a rat model.
    Neurourology and urodynamics, 2019, Volume: 38, Issue:8

    Topics: Animals; Collagen; Cyclooxygenase 2; Cystitis; Drugs, Chinese Herbal; Female; Fibronectins; Functional Neuroimaging; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Ketamine; Magnetic Resonance Imaging; NF-kappa B; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sensory Receptor Cells; Substance P; Transforming Growth Factor beta1; TRPV Cation Channels; Tumor Necrosis Factor-alpha; Urinary Bladder; Urinary Bladder, Overactive; Urothelium

2019
Role of c-Jun N-terminal kinase (JNK) activation in micturition reflexes in cyclophosphamide (CYP)-induced cystitis in female rats.
    Journal of molecular neuroscience : MN, 2014, Volume: 54, Issue:3

    Topics: Animals; Anthracenes; Calcitonin Gene-Related Peptide; Cyclophosphamide; Cystitis; Female; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Wistar; Reflex; Substance P; Urinary Bladder; Urination

2014
The effects of tempol on cyclophosphamide-induced oxidative stress in rat micturition reflexes.
    TheScientificWorldJournal, 2015, Volume: 2015

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Calcitonin Gene-Related Peptide; Cyclic N-Oxides; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Oxidative Stress; Rats; Reactive Nitrogen Species; Reflex; Spin Labels; Substance P; Tyrosine; Urination

2015
PACAP-mediated ATP release from rat urothelium and regulation of PACAP/VIP and receptor mRNA in micturition pathways after cyclophosphamide (CYP)-induced cystitis.
    Journal of molecular neuroscience : MN, 2008, Volume: 36, Issue:1-3

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cyclophosphamide; Cystitis; Galanin; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Vasoactive Intestinal Peptide; Signal Transduction; Substance P; Urination; Urothelium; Vasoactive Intestinal Peptide

2008
Neonatal bladder inflammation produces functional changes and alters neuropeptide content in bladders of adult female rats.
    The journal of pain, 2010, Volume: 11, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Cystitis; Disease Models, Animal; Evans Blue; Female; Irritants; Mustard Plant; Neuropeptides; Nociceptors; Plant Oils; Rats; Sensory Receptor Cells; Substance P; Time; Urinary Bladder; Zymosan

2010
Effects of acute adult and early-in-life bladder inflammation on bladder neuropeptides in adult female rats.
    BMC urology, 2011, Aug-15, Volume: 11

    Topics: Acute Disease; Age Factors; Animals; Calcitonin Gene-Related Peptide; Cystitis; Estrous Cycle; Female; Rats; Rats, Sprague-Dawley; Substance P; Urinary Bladder

2011
Effects of CYP-induced cystitis on PACAP/VIP and receptor expression in micturition pathways and bladder function in mice with overexpression of NGF in urothelium.
    Journal of molecular neuroscience : MN, 2012, Volume: 48, Issue:3

    Topics: Animals; Cyclophosphamide; Cystitis; Disease Progression; Galanin; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth; Nerve Growth Factor; Organ Specificity; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Receptors, Vasoactive Intestinal Peptide, Type II; Receptors, Vasoactive Intestinal Polypeptide, Type I; Recombinant Fusion Proteins; Reflex, Abnormal; RNA, Messenger; Substance P; Urinary Bladder; Urination; Urothelium; Vasoactive Intestinal Peptide

2012
Mast cells mediate substance P-induced bladder inflammation through an NK(1) receptor-independent mechanism.
    American journal of physiology. Renal physiology, 2002, Volume: 283, Issue:4

    Topics: Animals; Cell Count; Cystitis; DNA, Complementary; Down-Regulation; Female; Mast Cells; Mice; Mice, Knockout; Multigene Family; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-kit; Receptors, Neurokinin-1; Reproducibility of Results; Substance P; Urinary Bladder

2002
Connective molecular pathways of experimental bladder inflammation.
    Physiological genomics, 2003, Nov-11, Volume: 15, Issue:3

    Topics: Animals; Cluster Analysis; Cystitis; Dinitrophenols; Female; Gene Expression Profiling; Gene Expression Regulation; Genetic Variation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Ovalbumin; Serum Albumin; Substance P

2003
Intraluminal antibodies to macrophage migration inhibitory factor decrease substance P induced inflammatory changes in the rat bladder and prostate.
    The Journal of urology, 2004, Volume: 172, Issue:4 Pt 1

    Topics: Animals; Antibodies; Cystitis; Cytokines; Immunoenzyme Techniques; Macrophage Migration-Inhibitory Factors; Male; Prostate; Prostatitis; Rats; Rats, Sprague-Dawley; Substance P; Urinary Bladder

2004
Elimination of rat spinal neurons expressing neurokinin 1 receptors reduces bladder overactivity and spinal c-fos expression induced by bladder irritation.
    American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:3

    Topics: Animals; Capsaicin; Cell Nucleus; Cystitis; Female; Fluorescent Antibody Technique; Genes, fos; Immunohistochemistry; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Urinary Bladder; Urinary Bladder, Neurogenic

2005
Macrophage migration inhibitory factor is released as a complex with alpha1-inhibitor-3 in the intraluminal fluid during bladder inflammation in the rat.
    The Journal of urology, 2005, Volume: 174, Issue:1

    Topics: Acute-Phase Proteins; Animals; Body Fluids; Capsaicin; Cystitis; Macrophage Migration-Inhibitory Factors; Male; Rats; Substance P

2005
Substance P induces localization of MIF/alpha1-inhibitor-3 complexes to umbrella cells via paracellular transit through the urothelium in the rat bladder.
    BMC urology, 2006, Sep-18, Volume: 6

    Topics: Acute-Phase Proteins; Animals; Cystitis; Macrophage Migration-Inhibitory Factors; Male; Protein Transport; Rats; Substance P; Tissue Distribution; Urinary Bladder; Urothelium

2006
Cyclophosphamide induced cystitis: role of nitric oxide synthase, cyclooxygenase-1 and 2, and NK(1) receptors.
    The Journal of urology, 2007, Volume: 177, Issue:4

    Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cyclophosphamide; Cystitis; Male; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P

2007
Regulatory network of inflammation downstream of proteinase-activated receptors.
    BMC physiology, 2007, Mar-30, Volume: 7

    Topics: Animals; Antigens; Calcium; Chromatin; Cystitis; Female; Gene Expression; Gene Expression Regulation; Genome; Immunoprecipitation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Phospholipases A; Polymerase Chain Reaction; Receptor, PAR-1; Subcellular Fractions; Substance P; Urinary Bladder

2007
Mandatory role of proteinase-activated receptor 1 in experimental bladder inflammation.
    BMC physiology, 2007, Mar-30, Volume: 7

    Topics: Animals; Antigens; Cell Line; Cystitis; Edema; Granulocytes; Humans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, PAR-1; Receptor, PAR-2; Receptors, Proteinase-Activated; Substance P; Urinary Bladder; Urothelium

2007
Does the mast cell have an intrinsic role in the pathogenesis of interstitial cystitis?
    Agents and actions, 1994, Volume: 41 Spec No

    Topics: Calcimycin; Cystitis; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Mast Cells; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Substance P; Urinary Bladder

1994
Increased number of substance P positive nerve fibres in interstitial cystitis.
    British journal of urology, 1995, Volume: 75, Issue:6

    Topics: Adult; Animals; Cystitis; Female; Humans; Mast Cells; Middle Aged; Nerve Fibers; Rats; Rats, Sprague-Dawley; Substance P; Urinary Bladder

1995
Effect of bradykinin and tachykinin receptor antagonist on xylene-induced cystitis in rats.
    The Journal of urology, 1993, Volume: 150, Issue:3

    Topics: Administration, Intravesical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Bradykinin; Cystitis; Female; Rats; Rats, Wistar; Substance P; Xylenes

1993
Kinetics of peptide-induced release of inflammatory mediators by the urinary bladder.
    British journal of urology, 1997, Volume: 80, Issue:5

    Topics: Animals; Bradykinin; Cystitis; Dinoprost; Dinoprostone; Female; Guinea Pigs; Histamine; Inflammation Mediators; Leukotriene B4; Peptides; Somatostatin; Substance P

1997
Role of substance P in several models of bladder inflammation.
    Urological research, 1997, Volume: 25, Issue:6

    Topics: Animals; Biphenyl Compounds; Cystitis; Disease Models, Animal; Female; Immunohistochemistry; Lipopolysaccharides; Neurokinin-1 Receptor Antagonists; Poly I-C; Rats; Substance P; Urinary Bladder; Urination; Xylenes

1997
Mast cells mediate the severity of experimental cystitis in mice.
    The Journal of urology, 1999, Volume: 162, Issue:1

    Topics: Animals; Cystitis; Female; Lipopolysaccharides; Mast Cells; Mice; Severity of Illness Index; Substance P

1999
Substance P dependence of endosomal fusion during bladder inflammation.
    American journal of physiology. Renal physiology, 2000, Volume: 278, Issue:3

    Topics: Animals; Blotting, Western; Cystitis; Endosomes; Epithelium; Fluorescent Dyes; Guinea Pigs; In Vitro Techniques; Male; Microscopy, Confocal; Ovalbumin; Rabbits; Rats; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Urinary Bladder

2000
Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene.
    Neuroscience, 2000, Volume: 98, Issue:2

    Topics: Acetic Acid; Animals; Behavior, Animal; Capsaicin; Colon; Cyclophosphamide; Cystitis; Female; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Mustard Plant; Nociceptors; Pain; Physical Stimulation; Plant Extracts; Plant Oils; Receptors, Neurokinin-1; Substance P; Urinary Bladder; Visceral Afferents

2000
Gene-regulation during bladder neurogenic inflammation.
    Urology, 2001, Volume: 57, Issue:6 Suppl 1

    Topics: Cystitis; Cytokines; Mast Cells; Receptors, Neurokinin-1; Substance P; Up-Regulation

2001
LPS-sensory peptide communication in experimental cystitis.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:2

    Topics: Administration, Intravesical; Animals; Contrast Media; Cystitis; Disease Models, Animal; Drug Synergism; Female; Fluorescein; Histamine; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Neurons, Afferent; Neutrophils; Substance P; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Urinary Bladder; Urothelium

2002
Gene expression profiling of mouse bladder inflammatory responses to LPS, substance P, and antigen-stimulation.
    The American journal of pathology, 2002, Volume: 160, Issue:6

    Topics: Animals; Cystitis; Dinitrophenols; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Markers; Haptens; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Prognosis; Reproducibility of Results; Serum Albumin; Substance P; Up-Regulation

2002
Detrusor hyperreflexia induced by intravesical instillation of xylene in conscious rats.
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:4

    Topics: Acetylcholine; Animals; Cystitis; Dinoprostone; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Reflex; Substance P; Urinary Bladder; Xylenes

1990