Page last updated: 2024-08-23

substance p and Corneal Diseases

substance p has been researched along with Corneal Diseases in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (9.52)	18.2507
2000's	10 (47.62)	29.6817
2010's	6 (28.57)	24.3611
2020's	3 (14.29)	2.80

Authors

Authors	Studies
Barbariga, M; Ferrari, G; Fonteyne, P; Lasagni Vitar, R; Rama, P; Triani, F	1
Issar, T; Krishnan, AV; Kwai, N; Markoulli, M; Pisarcikova, J; Poynten, AM; Tummanapalli, SS; Willcox, MDP	1
Barbariga, M; Bignami, F; Ferrari, G; Fonteyne, P; Lasagni Vitar, RM; Rama, P	1
Duong, CL; Karras, J; Kim, J; Lum, E; Markoulli, M; Tolentino, JB; You, J	1
Karamichos, D; Ma, JX; Priyadarsini, S; Rowsey, TG	1
Aldave, AJ; Chodosh, J; Lin, SR	1
Agogo, GO; Guo, J; Peng, L; Yan, M	1
Inui, M; Nishida, T; Nomizu, M	1
Nishida, T; Yanai, R	1
Chikama, T; Chikamoto, N; Ishimitsu, T; Kamiya, A; Nishida, T; Yamada, N	1
Kao, WW; Kitano, A; Okada, Y; Reinach, PS; Saika, S; Shirai, K	1
Kawahara, M; Nakamura, M; Nakata, K; Nishida, T	1
Ikuse, T; Nagano, T; Nakamura, M; Nakata, K; Nishida, T; Okahara, A; Takase, K; Yamaguchi, T	1
Kawai, M; Mashima, Y; Nishida, T; Ogata, M; Yamada, M	1
Dogru, M; Goto, E; Ishida, R; Kojima, T; Matsumoto, Y; Ohashi, Y; Tsubota, K	1
Benitez-Del-Castillo, JM; Fontan-Rivas, E; Garcia-Sanchez, J; Martinez-de-la-Casa, JM; Rodríguez-Bayo, S	1
Brown, SM; Lamberts, DW; Murphy, CJ; Nishida, T; Reid, TW	1
Brown, SM; Enoki, M; Konma, T; Mannis, MJ; Murphy, CJ; Nagano, K; Nakamura, M; Nishida, T; Ofuji, K; Reid, TW; Tanaka, T	1
Kawai, M; Mashima, Y; Ogata, M; Yamada, M	1
Abrams, GA; Bentley, E; Campbell, S; Marfurt, CF; McDermott, A; Murphy, CJ; Reid, TW	1
Barney, NP; Lee, CH; Murphy, CJ; Reid, TW; Taylor, PB; Whiteman, AL	1

Reviews

6 review(s) available for substance p and Corneal Diseases

Article	Year
Recurrent corneal erosion syndrome. The British journal of ophthalmology, 2019, Volume: 103, Issue:9 Topics: Corneal Diseases; Corneal Dystrophies, Hereditary; Corneal Surgery, Laser; Diagnosis, Differential; Epithelium, Corneal; Humans; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Substance P	2019
Substance P and fibrotic diseases. Neuropeptides, 2019, Volume: 76 Topics: Animals; Corneal Diseases; Fibrosis; Heart Diseases; Humans; Inflammation; Joint Diseases; Kidney Diseases; Liver Cirrhosis; Primary Myelofibrosis; Substance P; Wound Healing	2019
Peptide therapies for ocular surface disturbances based on fibronectin-integrin interactions. Progress in retinal and eye research, 2015, Volume: 47 Topics: Animals; Corneal Diseases; Disease Models, Animal; Epithelium, Corneal; Fibronectins; Humans; Insulin-Like Growth Factor I; Integrins; Molecular Targeted Therapy; Peptides; Substance P; Wound Healing	2015
Advances in treatment for neurotrophic keratopathy. Current opinion in ophthalmology, 2009, Volume: 20, Issue:4 Topics: Corneal Diseases; Epithelium, Corneal; Humans; Insulin-Like Growth Factor I; Neurotransmitter Agents; Ophthalmic Solutions; Substance P; Trigeminal Nerve; Wound Healing	2009
Neurotrophic keratopathy; its pathophysiology and treatment. Histology and histopathology, 2010, Volume: 25, Issue:6 Topics: Animals; Cell Movement; Cell Survival; Cornea; Corneal Diseases; Disease Models, Animal; Epithelium, Corneal; Gene Expression Regulation; Humans; Signal Transduction; Substance P; Trigeminal Nerve; Trigeminal Nerve Injuries; TRPC Cation Channels; Wound Healing	2010
[Neurotrophic keratopathy--studies on substance P and the clinical significance of corneal sensation]. Nippon Ganka Gakkai zasshi, 1997, Volume: 101, Issue:12 Topics: Animals; Cell Movement; Cornea; Corneal Diseases; Epithelium, Corneal; Humans; Insulin-Like Growth Factor I; Paralysis; Rabbits; Sensation; Substance P; Trigeminal Nerve	1997

Trials

1 trial(s) available for substance p and Corneal Diseases

Article	Year
Efficacy of substance P and insulin-like growth factor-1 peptides for preventing postsurgical superficial punctate keratopathy in diabetic patients. Japanese journal of ophthalmology, 2009, Volume: 53, Issue:5 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Corneal Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Epithelium, Corneal; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Oligopeptides; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Substance P; Treatment Outcome	2009

Article

Year

Efficacy of substance P and insulin-like growth factor-1 peptides for preventing postsurgical superficial punctate keratopathy in diabetic patients.

Japanese journal of ophthalmology, 2009, Volume: 53, Issue:5

Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Corneal Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Epithelium, Corneal; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Oligopeptides; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Substance P; Treatment Outcome

2009

Other Studies

14 other study(ies) available for substance p and Corneal Diseases

Article	Year
Substance P/neurokinin-1 receptor pathway blockade ameliorates limbal stem cell deficiency by modulating mTOR pathway and preventing cell senescence. Stem cell reports, 2022, 04-12, Volume: 17, Issue:4 Topics: Cellular Senescence; Corneal Diseases; Epithelium, Corneal; Humans; Limbus Corneae; Receptors, Neurokinin-1; Stem Cells; Substance P; TOR Serine-Threonine Kinases	2022
A Comparative Study on the Diagnostic Utility of Corneal Confocal Microscopy and Tear Neuromediator Levels in Diabetic Peripheral Neuropathy. Current eye research, 2020, Volume: 45, Issue:8 Topics: Adult; Area Under Curve; Calcitonin Gene-Related Peptide; Cornea; Corneal Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Microscopy, Confocal; Middle Aged; Prospective Studies; ROC Curve; Substance P; Tears; Trigeminal Nerve Diseases	2020
Modulating Ocular Surface Pain Through Neurokinin-1 Receptor Blockade. Investigative ophthalmology & visual science, 2021, 03-01, Volume: 62, Issue:3 Topics: Administration, Ophthalmic; Animals; Cornea; Corneal Diseases; Disease Models, Animal; Eye Pain; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Neurokinin-1 Receptor Antagonists; Nociception; Ophthalmic Solutions; Substance P; Tears; Trigeminal Nerve	2021
Corneal Nerve Morphology and Tear Film Substance P in Diabetes. Optometry and vision science : official publication of the American Academy of Optometry, 2017, Volume: 94, Issue:7 Topics: Case-Control Studies; Cornea; Corneal Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Eye Proteins; Female; Humans; Male; Microscopy, Confocal; Middle Aged; Nerve Fibers; Prospective Studies; Substance P; Tears; Trigeminal Nerve; Trigeminal Nerve Diseases	2017
Unravelling the stromal-nerve interactions in the human diabetic cornea. Experimental eye research, 2017, Volume: 164 Topics: Biomarkers; Case-Control Studies; Cell Differentiation; Cells, Cultured; Coculture Techniques; Collagen; Corneal Diseases; Corneal Stroma; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Extracellular Matrix; Female; Fibroblasts; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Models, Biological; Neurons; Receptor, IGF Type 1; Substance P; Tubulin	2017
Restoration of corneal epithelial barrier function and wound healing by substance P and IGF-1 in rats with capsaicin-induced neurotrophic keratopathy. Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:7 Topics: Administration, Topical; Animals; Biological Transport; Capsaicin; Cornea; Corneal Diseases; Disease Models, Animal; Drug Therapy, Combination; Epithelium, Corneal; Female; Fluorescein; Fluorophotometry; Insulin-Like Growth Factor I; Male; Ophthalmic Solutions; Pregnancy; Rats; Rats, Wistar; Substance P; Tears; Trigeminal Nerve Diseases; Wound Healing	2003
Effects of substance P and IGF-1 in corneal epithelial barrier function and wound healing in a rat model of neurotrophic keratopathy. Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:9 Topics: Animals; Biological Transport; Cell Membrane Permeability; Corneal Diseases; Cranial Nerve Diseases; Denervation; Disease Models, Animal; Drug Therapy, Combination; Epithelium, Corneal; Fluorescein; Fluorophotometry; Insulin-Like Growth Factor I; Male; Ophthalmic Nerve; Ophthalmic Solutions; Rats; Rats, Inbred BN; Substance P; Tears; Wound Healing	2003
Substance P in human tears. Cornea, 2003, Volume: 22, Issue:7 Suppl Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatography, High Pressure Liquid; Corneal Diseases; Diclofenac; Enzymes; Female; Humans; Hypesthesia; Immunoenzyme Techniques; Male; Middle Aged; Substance P; Tears	2003
Autologous serum application in the treatment of neurotrophic keratopathy. Ophthalmology, 2004, Volume: 111, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Cornea; Corneal Diseases; Cranial Nerve Diseases; Enzyme-Linked Immunosorbent Assay; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Nerve Growth Factor; Ophthalmic Nerve; Radioimmunoassay; Retrospective Studies; Serum; Substance P; Tears	2004
Treatment of recurrent corneal erosion with substance P-derived peptide and insulin-like growth factor I. Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:10 Topics: Adult; Corneal Diseases; Drug Therapy, Combination; Epithelium, Corneal; Female; Humans; Insulin-Like Growth Factor I; Microscopy, Confocal; Peptide Fragments; Recurrence; Substance P	2005
Neurotrophic and anhidrotic keratopathy treated with substance P and insulinlike growth factor 1. Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:7 Topics: Administration, Topical; Cornea; Corneal Diseases; Female; Follow-Up Studies; Humans; Infant; Insulin-Like Growth Factor I; Keratoplasty, Penetrating; Ophthalmic Solutions; Substance P; Tears; Trigeminal Nerve	1997
Decreased substance P concentrations in tears from patients with corneal hypesthesia. American journal of ophthalmology, 2000, Volume: 129, Issue:5 Topics: Adult; Aged; Cornea; Corneal Diseases; Denervation; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Female; Humans; Hypesthesia; Male; Middle Aged; Substance P; Tears	2000
Spontaneous chronic corneal epithelial defects (SCCED) in dogs: clinical features, innervation, and effect of topical SP, with or without IGF-1. Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:10 Topics: Administration, Topical; Animals; Calcitonin Gene-Related Peptide; Chronic Disease; Corneal Diseases; Dog Diseases; Dogs; Drug Therapy, Combination; Epithelium, Corneal; Female; Fluorophotometry; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Substance P; Thiolester Hydrolases; Trigeminal Nerve; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide	2001
Substance P, insulinlike growth factor 1, and surface healing. Archives of ophthalmology (Chicago, Ill. : 1960), 2002, Volume: 120, Issue:2 Topics: Aged; Anti-Bacterial Agents; Antihypertensive Agents; Brimonidine Tartrate; Corneal Diseases; Drug Therapy, Combination; Epithelium, Corneal; Female; Humans; Insulin-Like Growth Factor I; Keratoplasty, Penetrating; Ophthalmic Solutions; Polymyxin B; Quinoxalines; Substance P; Wound Healing	2002