Page last updated: 2024-08-23

substance p and Colitis

substance p has been researched along with Colitis in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	15 (26.32)	18.2507
2000's	26 (45.61)	29.6817
2010's	16 (28.07)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fang, K; Huang, V; Iliopoulos, D; Kevil, CG; Law, IKM; Padua, D; Pothoulakis, C; Sideri, A	1
Amagase, K; Kato, S; Matsumoto, K; Tominaga, M; Tsukahara, T; Utsumi, D	1
Dong, L; Guan, HT; Luo, JY; Ma, H; Wang, XQ; Zhao, P	1
Chen, T; Ji, W; Li, H; Li, YQ; Pei, LY; Wang, W; Wu, SX; Zhang, MM; Zhang, T	1
Altier, C; Benson, JR; Lapointe, TK; Lomax, AE; Moynes, DM; Vanner, SJ; Xu, J	1
Malykhina, AP; Pan, XQ	1
Altier, C; Basso, L; Chapman, K; Dietrich, G; Flynn, R; Iftinca, MC; Lapointe, TK; Vergnolle, N	1
Amagase, K; Horie, S; Kato, S; Matsumoto, K; Utsumi, D	1
De Ponti, F; Ursino, MG; Vasina, V	1
Jiang, HJ; Lin, P; Mei, L; Pan, H; Wu, XY	1
Bunnett, NW; Cattaruzza, F; Grady, EF; Miranda-Morales, M; Spreadbury, I; Vanner, S	1
Chacko, S; Chang, S; Gonzalez, JA; Malykhina, AP; Pan, XQ; Wein, AJ	1
Fazelbhoy, Z; Gerard, N; Hing, T; Karagiannides, I; Koon, HW; Lu, B; Pothoulakis, C; Shih, D; Xu, H; Zhao, D	1
Ahuja, A; Cserjesi, P; D'Autréaux, F; Gershon, MD; Karamooz, N; Li, Z; Margolis, KG; Mawe, G; Morikawa, Y; Roberts, J; Setlick, W; Stevanovic, K	1
Babes, A; Becker, C; Eberhardt, M; Engel, MA; Filipović, MR; Ivanović-Burmazović, I; Izydorczyk, I; Khalil, M; Kichko, TI; Leffler, A; Mueller-Tribbensee, SM; Nau, C; Neuhuber, WL; Neurath, MF; Niedermirtl, F; Reeh, PW; Siklosi, N; Zimmermann, K	1
Chen, J; Hing, TC; Ho, S; Koon, HW; Pothoulakis, C; Shih, DQ; Targan, SR; Zhao, D	1
Becker, C; Engel, MA; Khalil, M; Mueller-Tribbensee, SM; Neuhuber, WL; Neurath, MF; Reeh, PW; Siklosi, N	1
Becker, C; Engel, MA; Khalil, M; Mueller-Tribbensee, SM; Neuhuber, WL; Neurath, MF; Reeh, PW	1
Adler, G; Eysselein, VE; Reinshagen, M	1
Depoortere, I; Peeters, TL; Thielemans, L; Thijs, T	1
Arsenescu, R; Blum, A; Bunnett, N; Elliott, D; Metwali, A; Weinstock, JV	1
Bossowska, A; Gonkowski, S; Kamińska, B; Korzon, M; Landowski, P; Majewski, M	1
Luo, JY; Sun, YN	1
Andry, CD; Becker, JM; Fruin, AB; Gonzales, KD; Gower, AC; O'Brien, M; Reed, KL; Stucchi, AF	1
Giorgadze, N; Karagiannides, I; Kirkland, JL; Kokkotou, E; Leeman, SE; O'Brien, M; Pothoulakis, C; Tansky, M; Tchkonia, T	1
Gutkin, DW; Pezzone, MA; Ustinova, EE	1
Koster, AS; Kraneveld, AD; Nijkamp, FP; Rijnierse, A; van Zijl, KM	1
Al-Mutawaly, N; Bercik, P; Blennerhassett, PA; Collins, SM; Ghia, JE; Verdu, EF; Verma-Gandhu, M	1
Cahill, CM; Henry, JL; Landau, AM; Ribeiro-da-Silva, A; St Louis, M; Yashpal, K	1
Koon, HW; Moyer, MP; Pothoulakis, C; Zhan, Y; Zhao, D	1
Appleyard, CB; Morales, M; Santiago, C	1
Berenshtein, E; Chevion, M; Goldin, E; Hershcovici, T; Israeli, E; Weiss, O; Wengrower, D; Zannineli, G	1
Humes, DJ; Jenkins, D; Scholefield, JH; Simpson, J; Spiller, RC; Sundler, F; Wakelin, D	1
Bataille, F; Bleich, A; Capellino, S; Falk, W; Grum, F; Obermeier, F; Schölmerich, J; Straub, RH; Strauch, U	1
Davis, W; Eysselein, V; Mueller, K; Nast, C; Patel, A; Reinshagen, M; Sottili, M	1
Chandel, B; Deshpande, Y; Kaminski, DL; Longo, WE; Niehoff, M; Polities, G; Robinson, S; Vernava, AM	1
Greenlees, C; Medhurst, AD; Parsons, AA; Smith, SJ	1
de las Alas, MM; Doria, M; Gaginella, TS; Kachur, JF; Keshavarzian, A; Sundaresan, R; Walsh, R	1
Eysselein, VE; French, S; Patel, A; Reinshagen, M; Sottili, M; Sternini, C	1
Ahlman, H; Björck, S; Dahlström, A; Jennische, E	1
Miampamba, M; Sharkey, KA	1
Angelucci, D; Büchler, MW; Di Mola, FF; Di Sebastiano, P; Friess, H; Grossi, L; Innocenti, P; Marzio, L	1
Depoortere, I; Geboes, K; Peeters, TL; Thijs, T; Van Assche, G	1
Gebhart, GF; Hutchcroft, K; Traub, RJ	1
Barbara, G; Bunnett, NW; Collins, SM; Figini, M; Geppetti, P; Gerard, C; Gerard, N; Grady, EF; Qiu, B; Sturiale, S	1
Bossone, C; Goldhill, JM; Hosseini, JM; Piñeiro-Carrero, V; Shea-Donohue, T	1
Adler, G; Eysselein, VE; Flämig, G; Geerling, I; Lieb, K; Reinshagen, M; Rohm, H; Steinkamp, M; Von Herbay, A	1
Depoortere, I; Keith, JC; Peeters, TL; Thijs, T; van Assche, G	1
Becker, JM; Beer, E; Leeman, S; Materne, O; McClung, J; Moore, F; O'Brien, M; Shebani, K; Shofer, S; Stucchi, AF	1
Depoortere, I; Keith, JC; Peeters, TL; Thielemans, L; Thijs, T; Van Assche, G	1
Lu, Y; Westlund, KN	1
Hoppe, S; Jehle, EC; Michel, K; Neunlist, M; Schemann, M; Schneider, J; Starlinger, MJ	1
Bueno, L; Coelho, AM; Fioramonti, J; Guiard, B; Vergnolle, N	1
Altdorfer, K; Bagaméri, G; Fehér, E; Fehér, J	1
Castagliuolo, I; Gerard, NP; Keates, AC; Lu, B; Morteau, O; Pothoulakis, C; Valenick, L; Wang, CC; Zacks, J	1
Chayvialle, JA; Chéry-Croze, S; Miampamba, M	1
Anderson, K; Bernstein, D; Cominelli, F; Davis, W; Eysselein, VE; Khan, H; Nast, CC; Patel, A; Reinshagen, M; Sternini, C	1

Other Studies

57 other study(ies) available for substance p and Colitis

Article	Year
MicroRNA-31-3p Is Involved in Substance P (SP)-Associated Inflammation in Human Colonic Epithelial Cells and Experimental Colitis. The American journal of pathology, 2018, Volume: 188, Issue:3 Topics: Animals; Cell Line; Colitis; Colon; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Humans; Inflammation; MAP Kinase Signaling System; Mice; MicroRNAs; Substance P	2018
Transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 contribute to the progression of colonic inflammation in dextran sulfate sodium-induced colitis in mice: Links to calcitonin gene-related peptide and substance P. Journal of pharmacological sciences, 2018, Volume: 136, Issue:3 Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colitis; Dextran Sulfate; Disease Models, Animal; Disease Progression; Male; Mice, Inbred C57BL; Nerve Fibers; Pain; Substance P; TRPA1 Cation Channel; TRPV Cation Channels; Up-Regulation	2018
Possible role of mast cells and neuropeptides in the recovery process of dextran sulfate sodium-induced colitis in rats. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2013, Volume: 28, Issue:1 Topics: Animals; Colitis; Dextran Sulfate; Histamine; Male; Mast Cells; Neuropeptides; Rats; Rats, Sprague-Dawley; Somatostatin; Substance P; Vasoactive Intestinal Peptide	2013
Acute colitis induces neurokinin 1 receptor internalization in the rat lumbosacral spinal cord. PloS one, 2013, Volume: 8, Issue:3 Topics: Acute Disease; Animals; Colitis; Colon; Formaldehyde; Gene Expression; Lumbosacral Region; Male; Neurokinin-1 Receptor Antagonists; Neurons; Nociception; Nociceptive Pain; Protein Transport; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Tryptophan	2013
Sustained neurochemical plasticity in central terminals of mouse DRG neurons following colitis. Cell and tissue research, 2014, Volume: 356, Issue:2 Topics: Animals; Colitis; Dextran Sulfate; Ganglia, Spinal; Inflammation; Intestines; Lumbosacral Region; Male; Mice; Neuronal Plasticity; Pain; Posterior Horn Cells; Substance P	2014
Estrous cycle dependent fluctuations of regulatory neuropeptides in the lower urinary tract of female rats upon colon-bladder cross-sensitization. PloS one, 2014, Volume: 9, Issue:5 Topics: Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Colitis; Colon; Estrous Cycle; Female; Ganglia, Spinal; Gonadal Steroid Hormones; Nerve Growth Factors; Neuropeptides; Peroxidase; Rats; Substance P; Urinary Bladder	2014
TRPV1 sensitization mediates postinflammatory visceral pain following acute colitis. American journal of physiology. Gastrointestinal and liver physiology, 2015, Jul-15, Volume: 309, Issue:2 Topics: Abdominal Pain; Acute Disease; Animals; Behavior, Animal; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Ganglia, Spinal; HEK293 Cells; Humans; Hyperalgesia; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; Pain Measurement; Pain Threshold; Signal Transduction; Substance P; Time Factors; Transfection; TRPV Cation Channels; Visceral Pain	2015
5-HT3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis. British journal of pharmacology, 2016, Volume: 173, Issue:11 Topics: Animals; Benzimidazoles; Colitis; Colon; Dextran Sulfate; Dose-Response Relationship, Drug; Inflammation; Male; Mice; Mice, Inbred C57BL; Ondansetron; Receptors, Neurokinin-1; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship; Substance P	2016
Protection from DNBS-induced colitis by the tachykinin NK(1) receptor antagonist SR140333 in rats. European journal of pharmacology, 2009, Jan-28, Volume: 603, Issue:1-3 Topics: Animals; Colitis; Dinitrofluorobenzene; Humans; Inflammation; Intestinal Mucosa; Intestines; Male; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Substance P; Substrate Specificity; Tumor Necrosis Factor-alpha	2009
Rat colitis induced by intrathecal injection of substance P. Sheng li xue bao : [Acta physiologica Sinica], 2009, Aug-25, Volume: 61, Issue:4 Topics: Animals; Colitis; Colon; Disease Models, Animal; Inflammation; Injections, Spinal; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Male; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P	2009
Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice. American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:1 Topics: Aldehydes; Animals; Calcitonin Gene-Related Peptide; Colitis; Colon; Cysteine Proteinase Inhibitors; Efferent Pathways; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mustard Plant; Nociceptors; Pain; Plant Oils; Pregnancy; Proto-Oncogene Proteins c-fos; Receptor, PAR-2; RNA, Messenger; Spinal Cord; Substance P; Transient Receptor Potential Channels; TRPA1 Cation Channel; Visceral Afferents	2010
Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways. Experimental neurology, 2010, Volume: 225, Issue:2 Topics: Animals; Calcitonin Gene-Related Peptide; Colitis; Colon; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensory Receptor Cells; Signal Transduction; Substance P; Trinitrobenzenesulfonic Acid; TRPV Cation Channels; Urinary Bladder	2010
Substance P modulates colitis-associated fibrosis. The American journal of pathology, 2010, Volume: 177, Issue:5 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Movement; Colitis; Collagen; Colon; Fibroblasts; Fibrosis; Humans; Insulin-Like Growth Factor I; Intestinal Mucosa; Mice; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Proto-Oncogene Proteins c-akt; Receptors, Neurokinin-1; Substance P; Transforming Growth Factor beta1; Trinitrobenzenesulfonic Acid; Vimentin	2010
Expression level of Hand2 affects specification of enteric neurons and gastrointestinal function in mice. Gastroenterology, 2011, Volume: 141, Issue:2 Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Calbindin 2; Cell Count; Colitis; Colon; ELAV Proteins; ELAV-Like Protein 2; ELAV-Like Protein 3; ELAV-Like Protein 4; Enteric Nervous System; Gastrointestinal Motility; Genotype; Intercellular Junctions; Mice; Muscle, Smooth; Neuroglia; Neurons; Nitric Oxide Synthase; S100 Calcium Binding Protein G; Substance P; Synaptic Transmission; Trinitrobenzenesulfonic Acid; Vasoactive Intestinal Peptide	2011
TRPA1 and substance P mediate colitis in mice. Gastroenterology, 2011, Volume: 141, Issue:4 Topics: Aldehydes; Animals; Calcitonin Gene-Related Peptide; Calcium; Calcium Channels; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Diterpenes; Ganglia, Spinal; HEK293 Cells; Humans; Inflammation Mediators; Lipid Peroxidation; Membrane Potentials; Mice; Mice, Knockout; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Substance P; Transfection; Transient Receptor Potential Channels; Trinitrobenzenesulfonic Acid; TRPA1 Cation Channel; TRPV Cation Channels	2011
Substance P induces CCN1 expression via histone deacetylase activity in human colonic epithelial cells. The American journal of pathology, 2011, Volume: 179, Issue:5 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Colitis; Cysteine-Rich Protein 61; Dextran Sulfate; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Green Fluorescent Proteins; Histone Deacetylases; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Neurotransmitter Agents; Real-Time Polymerase Chain Reaction; Substance P; Transfection; Wound Healing	2011
Opposite effects of substance P and calcitonin gene-related peptide in oxazolone colitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:1 Topics: Animals; Calcitonin Gene-Related Peptide; Colitis; Colon; Cytokines; Enzyme-Linked Immunosorbent Assay; Inflammatory Bowel Diseases; Mice; Mice, Knockout; Oxazolone; Substance P	2012
The proximodistal aggravation of colitis depends on substance P released from TRPV1-expressing sensory neurons. Journal of gastroenterology, 2012, Volume: 47, Issue:3 Topics: Animals; Calcitonin Gene-Related Peptide; Colitis; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Sensory Receptor Cells; Severity of Illness Index; Substance P; TRPV Cation Channels	2012
Substance P gene expression in acute experimental colitis. Regulatory peptides, 1995, Sep-22, Volume: 59, Issue:1 Topics: Acute Disease; Animals; Colitis; Colon; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Gene Expression Regulation; Muscle, Smooth; Rabbits; Substance P	1995
Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation. Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:3 Topics: Adenosine Triphosphate; Animals; Colitis; Cyclooxygenase Inhibitors; Electric Stimulation; Female; In Vitro Techniques; Indomethacin; Male; Methiothepin; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Purinergic P2 Receptor Antagonists; Quinuclidines; Rabbits; Serotonin Antagonists; Substance P; Suramin; Trinitrobenzenesulfonic Acid	2003
Substance P regulates Th1-type colitis in IL-10 knockout mice. Journal of immunology (Baltimore, Md. : 1950), 2003, Oct-01, Volume: 171, Issue:7 Topics: Animals; Cells, Cultured; Chronic Disease; Colitis; Disease Models, Animal; Interleukin-10; Interleukin-12; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Piroxicam; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Th1 Cells	2003
The influence of experimental Bacteroides fragilis infection on substance P and somatostatin-immunoreactive neural elements in the porcine ascending colon - a preliminary report. Folia morphologica, 2003, Volume: 62, Issue:4 Topics: Animals; Bacteroides fragilis; Bacteroides Infections; Colitis; Colon, Ascending; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Myenteric Plexus; Nerve Fibers; Neurons; Somatostatin; Submucous Plexus; Substance P; Swine	2003
Effects of tegaserod on Fos, substance P and calcitonin gene-related peptide expression induced by colon inflammation in lumbarsacral spinal cord. World journal of gastroenterology, 2004, Jun-15, Volume: 10, Issue:12 Topics: Animals; Calcitonin Gene-Related Peptide; Colitis; Disease Models, Animal; Gastrointestinal Agents; Indoles; Male; Pain; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Visceral Afferents	2004
NF-kappaB activation precedes increases in mRNA encoding neurokinin-1 receptor, proinflammatory cytokines, and adhesion molecules in dextran sulfate sodium-induced colitis in rats. Digestive diseases and sciences, 2005, Volume: 50, Issue:12 Topics: Analysis of Variance; Animals; Base Sequence; Biopsy, Needle; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Immunohistochemistry; Inflammation Mediators; Male; Molecular Sequence Data; NF-kappa B; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Substance P	2005
Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes. Proceedings of the National Academy of Sciences of the United States of America, 2006, Mar-28, Volume: 103, Issue:13 Topics: Abdominal Fat; Animals; Cell Differentiation; Cells, Cultured; Chemotaxis; Colitis; Cytokines; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Keratinocytes; Mesentery; Mice; NF-kappa B; Phosphorylation; Receptors, Neurokinin-1; RNA, Messenger; Signal Transduction; Substance P; Time Factors; Trinitrobenzenesulfonic Acid	2006
Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides. American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:1 Topics: Anesthesia; Anesthetics, Intravenous; Animals; Bradykinin; Capsaicin; Chronic Disease; Colitis; Cystitis, Interstitial; Female; Mast Cells; Nerve Endings; Nerve Fibers, Unmyelinated; Neurons, Afferent; Neuropeptides; Pelvis; Physical Stimulation; Rats; Rats, Sprague-Dawley; Substance P; Trinitrobenzenesulfonic Acid; Urethane; Urinary Bladder	2007
Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice. European journal of pharmacology, 2006, Oct-24, Volume: 548, Issue:1-3 Topics: Animals; Capillary Permeability; Colitis; Colon; Diarrhea; Dinitrofluorobenzene; Disease Models, Animal; Haptens; Hypersensitivity; Indoles; Isoindoles; Male; Mast Cells; Mice; Mice, Inbred BALB C; Neurokinin-1 Receptor Antagonists; Substance P; Sulfonic Acids	2006
Visceral pain perception is determined by the duration of colitis and associated neuropeptide expression in the mouse. Gut, 2007, Volume: 56, Issue:3 Topics: Acute Disease; Animals; beta-Endorphin; CD4-Positive T-Lymphocytes; Chronic Disease; Colitis; Colon; Compliance; Interleukin-1beta; Male; Mice; Mice, Inbred BALB C; Neuropeptides; Pain; Pain Threshold; Physical Stimulation; Receptors, Opioid, mu; Substance P	2007
Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation. Neuroscience, 2007, Mar-16, Volume: 145, Issue:2 Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Colitis; Colon; Disease Models, Animal; Enteric Nervous System; Ethanol; Inflammation Mediators; Male; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Oligonucleotides, Antisense; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Sympathetic Nervous System; Zymosan	2007
Substance P mediates antiapoptotic responses in human colonocytes by Akt activation. Proceedings of the National Academy of Sciences of the United States of America, 2007, Feb-06, Volume: 104, Issue:6 Topics: Animals; Apoptosis; Cell Line; Colitis; Colon; Humans; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Substance P	2007
Chronic inflammation alters the contribution of neurokinin receptor subtypes to epithelial function in rat colon. Digestive diseases and sciences, 2008, Volume: 53, Issue:1 Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Benzamides; Colitis; Disease Models, Animal; Indomethacin; Intestinal Mucosa; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Stereoisomerism; Substance P; Tetrodotoxin; Trinitrobenzenesulfonic Acid	2008
The effect of restraint stress on the normal colon and on intestinal inflammation in a model of experimental colitis. Digestive diseases and sciences, 2008, Volume: 53, Issue:1 Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Colitis; Colon; Disease Models, Animal; Female; Intestinal Mucosa; Malondialdehyde; Oxidative Stress; Radioimmunoassay; Rats; Restraint, Physical; Severity of Illness Index; Stress, Physiological; Substance P; Trinitrobenzenesulfonic Acid	2008
Prolonged elevation of galanin and tachykinin expression in mucosal and myenteric enteric nerves in trinitrobenzene sulphonic acid colitis. Neurogastroenterology and motility, 2008, Volume: 20, Issue:4 Topics: Animals; Colitis; Galanin; Immunohistochemistry; Intestinal Mucosa; Male; Myenteric Plexus; Neurofilament Proteins; Neuropeptides; Rats; Rats, Sprague-Dawley; Substance P; Trinitrobenzenesulfonic Acid; Ubiquitin Thiolesterase	2008
Anti-inflammatory role of sympathetic nerves in chronic intestinal inflammation. Gut, 2008, Volume: 57, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Animals; Colitis; Colon; Crohn Disease; Dextran Sulfate; Disease Models, Animal; Diverticulitis, Colonic; Female; Humans; Interferon-gamma; Interleukin-10; Lymph Nodes; Male; Mesentery; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Middle Aged; Nerve Fibers; Substance P; Sympathetic Nervous System; Tumor Necrosis Factor-alpha	2008
Protective function of extrinsic sensory neurons in acute rabbit experimental colitis. Gastroenterology, 1994, Volume: 106, Issue:5 Topics: Animals; Blotting, Northern; Calcitonin Gene-Related Peptide; Capsaicin; Colitis; Colon; Disease Models, Animal; Intestinal Mucosa; Male; Necrosis; Neurons, Afferent; Rabbits; Radioimmunoassay; Substance P; Time Factors	1994
Effect of platelet-activating factor and its antagonists on colonic dysmotility and tissue levels of colonic neuropeptides. European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1 Topics: Alprazolam; Animals; Azepines; Colitis; Colon; Gastrointestinal Motility; In Vitro Techniques; Iodine Radioisotopes; Neuropeptides; Platelet Activating Factor; Rabbits; Substance P; Triazoles; Vasoactive Intestinal Peptide	1994
Nitric oxide synthase inhibitors 7- and 6-nitroindazole relax smooth muscle in vitro. European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1 Topics: Alprazolam; Animals; Azepines; Colitis; Colon; Gastrointestinal Motility; In Vitro Techniques; Iodine Radioisotopes; Neuropeptides; Platelet Activating Factor; Rabbits; Substance P; Triazoles; Vasoactive Intestinal Peptide	1994
Colitis reduces short-circuit current response to inflammatory mediators in rat colonic mucosa. Inflammation, 1995, Volume: 19, Issue:2 Topics: Alprostadil; Animals; Anions; Bradykinin; Carbachol; Colitis; Intestinal Mucosa; Male; Mitomycin; Neutrophils; Patch-Clamp Techniques; Peroxidase; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Secretory Rate; Serotonin; Substance P; Theophylline; Time Factors	1995
Action of sensory neurons in an experimental at colitis model of injury and repair. The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 1 Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Colitis; Colon; Intestinal Diseases; Intestinal Mucosa; Male; Neurons, Afferent; Peroxidase; Rats; Rats, Sprague-Dawley; Substance P; Ulcer; Wound Healing	1996
Influence of topical rectal application of drugs on dextran sulfate-induced colitis in rats. Digestive diseases and sciences, 1997, Volume: 42, Issue:4 Topics: Administration, Rectal; Aminosalicylic Acids; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antigen-Presenting Cells; Cell Membrane Permeability; Colitis; Colitis, Ulcerative; Colon; Coloring Agents; Dextran Sulfate; Evans Blue; Humans; Immunohistochemistry; Intestinal Absorption; Intestinal Mucosa; Lidocaine; Male; Mesalamine; Nerve Fibers; Neuropeptide Y; Prednisolone; Rats; Rats, Sprague-Dawley; S100 Proteins; Substance P; Sucralfate	1997
Distribution of calcitonin gene-related peptide, somatostatin, substance P and vasoactive intestinal polypeptide in experimental colitis in rats. Neurogastroenterology and motility, 1998, Volume: 10, Issue:4 Topics: Animals; Biomarkers; Calcitonin Gene-Related Peptide; Colitis; Ethanol; Immunohistochemistry; Male; Neurons; Neuropeptides; Rats; Rats, Wistar; Somatostatin; Substance P; Vasoactive Intestinal Peptide	1998
SR140333, a substance P receptor antagonist, influences morphological and motor changes in rat experimental colitis. Digestive diseases and sciences, 1999, Volume: 44, Issue:2 Topics: Animals; Colitis; Colon; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Substance P; Trinitrobenzenesulfonic Acid	1999
Differential changes in ACh-, motilin-, substance P-, and K(+)-induced contractility in rabbit colitis. The American journal of physiology, 1999, Volume: 277, Issue:1 Topics: Acetylcholine; Animals; Colitis; Colon; Female; Gastrointestinal Motility; In Vitro Techniques; Male; Motilin; Potassium; Rabbits; Substance P	1999
The peptide content of colonic afferents decreases following colonic inflammation. Peptides, 1999, Volume: 20, Issue:2 Topics: Abdominal Pain; Animals; Calcitonin Gene-Related Peptide; Colitis; Colon; Ganglia, Spinal; Lumbosacral Region; Male; Neuropeptides; Rats; Rats, Sprague-Dawley; Substance P; Thorax; Visceral Afferents	1999
Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P. Proceedings of the National Academy of Sciences of the United States of America, 1999, Sep-28, Volume: 96, Issue:20 Topics: Animals; Blood Proteins; Colitis; Dinitrofluorobenzene; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Neprilysin; Neurokinin-1 Receptor Antagonists; Peroxidase; Piperidines; Quinuclidines; Recombinant Proteins; Substance P	1999
Progressive alterations in circular smooth muscle contractility in TNBS-induced colitis in rats. Neurogastroenterology and motility, 1999, Volume: 11, Issue:5 Topics: Acetylcholine; Animals; Atropine; Colitis; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hexamethonium; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Nicotinic Antagonists; Parasympatholytics; Potassium Chloride; Rats; Rats, Sprague-Dawley; Substance P; Tetrodotoxin; Trinitrobenzenesulfonic Acid; Vasodilator Agents	1999
Protective role of neurotrophins in experimental inflammation of the rat gut. Gastroenterology, 2000, Volume: 119, Issue:2 Topics: Animals; Antibodies; Calcitonin Gene-Related Peptide; Colitis; Colon; Gene Expression; Male; Nerve Growth Factor; Neurotrophin 3; Neutralization Tests; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, trkA; Receptor, trkC; RNA, Messenger; Substance P; Tachykinins; Trinitrobenzenesulfonic Acid	2000
Dose-dependent effects of recombinant human interleukin-11 on contractile properties in rabbit 2,4,6-trinitrobenzene sulfonic acid colitis. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3 Topics: Acetylcholine; Animals; Colitis; Colon; Dinoprostone; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Interleukin-11; Male; Motilin; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neurokinin-1; Receptors, Neuropeptide; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substance P; Tensile Strength; Trinitrobenzenesulfonic Acid	2000
NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Colitis; Dextran Sulfate; Dinoprost; F2-Isoprostanes; Isomerism; Male; Neurokinin-1 Receptor Antagonists; Oxidative Stress; Rats; Rats, Sprague-Dawley; Substance P	2000
Effect of recombinant human interleukin-11 on motilin and substance P release in normal and inflamed rabbits. Regulatory peptides, 2001, Mar-02, Volume: 97, Issue:2-3 Topics: Animals; Base Sequence; Colitis; DNA Primers; Female; Humans; Interleukin-11; Intestinal Mucosa; Male; Motilin; Rabbits; Recombinant Proteins; RNA, Messenger; Substance P	2001
Effects of baclofen on colon inflammation-induced Fos, CGRP and SP expression in spinal cord and brainstem. Brain research, 2001, Jan-19, Volume: 889, Issue:1-2 Topics: Animals; Baclofen; Brain Stem; Calcitonin Gene-Related Peptide; Cell Count; Colitis; Colon; GABA Agonists; Gene Expression Regulation; Genes, fos; Immunohistochemistry; Kinetics; Male; Medulla Oblongata; Mustard Plant; Neurons; Plant Extracts; Plant Oils; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P	2001
Neurotransmitter coding of enteric neurones in the submucous plexus is changed in non-inflamed rectum of patients with Crohn's disease. Neurogastroenterology and motility, 2001, Volume: 13, Issue:3 Topics: Adolescent; Adult; Aged; Biopsy; Calcitonin Gene-Related Peptide; Choline O-Acetyltransferase; Colitis; Crohn Disease; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neurons; Nitric Oxide Synthase; Phosphopyruvate Hydratase; Rectum; Submucous Plexus; Substance P; Vasoactive Intestinal Peptide	2001
Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats. Gastroenterology, 2002, Volume: 122, Issue:4 Topics: Animals; Catheterization; Chelating Agents; Chromium Radioisotopes; Colitis; Colon; Compliance; Edetic Acid; Hyperalgesia; Injections, Intraperitoneal; Intestinal Absorption; Male; Neurons, Afferent; Oligopeptides; Prostaglandins; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptor, PAR-2; Receptors, Neurokinin-1; Receptors, Thrombin; Rectum; Signal Transduction; Spinal Cord; Substance P; Trypsin; Up-Regulation	2002
Neuroimmune interactions in experimental colitis. An immunoelectron microscopic study. Neuroimmunomodulation, 2001, Volume: 9, Issue:5 Topics: Animals; Cell Communication; Cell Count; Colitis; Colon; Enteric Nervous System; Immunohistochemistry; Lymphocytes; Male; Microscopy, Electron; Neuroimmunomodulation; Plasma Cells; Presynaptic Terminals; Rats; Rats, Wistar; Substance P; Synaptic Vesicles; Vasoactive Intestinal Peptide	2001
Protective effects of neurokinin-1 receptor during colitis in mice: role of the epidermal growth factor receptor. British journal of pharmacology, 2002, Volume: 136, Issue:2 Topics: Animals; Colitis; Dose-Response Relationship, Drug; ErbB Receptors; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Receptors, Neurokinin-1; Substance P	2002
Spinal and intestinal levels of substance P, calcitonin gene-related peptide and vasoactive intestinal polypeptide following perendoscopic injection of formalin in rat colonic wall. Neuropeptides, 1992, Volume: 22, Issue:2 Topics: Animals; Calcitonin Gene-Related Peptide; Colitis; Colon, Sigmoid; Colonoscopy; Female; Formaldehyde; Neuropeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Vasoactive Intestinal Peptide	1992
Calcitonin gene-related peptide and substance P decrease in the rabbit colon during colitis. A time study. Gastroenterology, 1991, Volume: 101, Issue:5 Topics: Animals; Antigen-Antibody Complex; Calcitonin Gene-Related Peptide; Colitis; Colon; Formaldehyde; Immunohistochemistry; Intestinal Mucosa; Male; Nerve Fibers; Neurons; Rabbits; Substance P; Time Factors	1991