substance p has been researched along with Chronic Pain in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 19 (73.08) | 24.3611 |
| 2020's | 6 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Hsieh, YL; Yang, CC; Yang, NP | 1 |
| Brzozowska, M; Całka, J; Jana, B | 1 |
| Meng, J; Tang, M; Wang, J | 1 |
| Fukushige, R; Hisaoka-Nakashima, K; Kishida, Y; Morioka, N; Nakamura, Y; Nakata, Y; Watanabe, K | 1 |
| Hsieh, YL; Wu, BT; Yang, CC | 1 |
| Kim, J; Kim, M | 1 |
| Guo, N; Hallberg, M; Nyberg, F; Nyman, J; Sandström, A; Yu, L | 1 |
| Gellatly, D; Heuston, CEM; Janzen, ED; Marti, S; Meléndez, DM; Moya, D; Pajor, EA; Schwartzkopf-Genswein, KS | 1 |
| Chen, W; Gaveriaux-Ruff, C; Hakimian, JK; Kieffer, BL; Marvizón, JCG; Severino, A; Walwyn, W | 1 |
| Zieglgänsberger, W | 1 |
| Chen, CC; Han, DS; Lee, CH; Shieh, YD | 1 |
| Buch, NS; Karlsson, P; Nikolajsen, L | 1 |
| Algenstaedt, P; Friedrichs, B; Hansen-Algenstaedt, N; Rüther, W; Schaefer, C; Schroeder, M; Viezens, L; Wiesner, L | 1 |
| Bäckryd, E; Gerdle, B; Ghafouri, B; Larsson, B | 1 |
| Camparis, CM; de Avila, ED; de Godoi Gonçalves, DA; de Molon, RS | 1 |
| Ganev, EG; Hiruma-Lima, CA; Martins, DF; Mazzardo-Martins, L; Nishijima, CM; Rocha, LR; Santos, AR | 1 |
| Chen, CC; Chen, WN | 1 |
| Andersen, ML; Araujo, P; Frange, C; Hachul, H; Hirotsu, C; Tufik, S | 1 |
| Frallonardo, P; Lorenzin, MG; Oliviero, F; Ortolan, A; Punzi, L; Ramonda, R; Scanu, A | 1 |
| Dai, GH; Deng, WT; Guo, XD; Huang, KB; Luo, GQ; Pan, SY; Peng, KR; Qian, NS; Wu, XN; Xiang, W; Yang, HJ; Zhang, T | 1 |
| Lisowska, B; Lisowski, A; Siewruk, K | 1 |
| Arrigoni-Blank, MF; Barreto, PA; Brito, RG; Camargo, ZT; Kolker, SJ; Lucca-Júnior, W; Quintans, JSS; Quintans-Júnior, LJ; Santos, PL; Scotti, L; Scotti, MT; Sluka, KA | 1 |
| Cohen, M; Lyon, P; Quintner, J | 1 |
| Chen, CC; Chen, CJ; Chen, WN; Lin, CC; Lin, YW; Zimmer, A | 1 |
| Clark, JD; Guo, TZ; Hou, S; Kingery, WS; Li, WW; Wei, T | 1 |
| Gendreau, JF; Kranzler, JD; Rao, SG | 1 |
6 review(s) available for substance p and Chronic Pain
| Article | Year |
|---|---|
Substance P and pain chronicity.
Topics: Animals; Chronic Pain; Humans; Memory; Models, Biological; Nerve Net; Nociception; Substance P | 2019 |
Relationship between levels of neuropeptide Substance P in periodontal disease and chronic pain: a literature review.
Topics: Alveolar Bone Loss; Chronic Pain; Gingival Crevicular Fluid; Humans; Neurogenic Inflammation; Periodontitis; Substance P | 2014 |
Fibromyalgia and sleep in animal models: a current overview and future directions.
Topics: Animals; Chronic Pain; Disease Models, Animal; Evidence-Based Medicine; Fatigue; Fibromyalgia; Humans; Pain Threshold; Rats; Serotonin; Severity of Illness Index; Sleep; Sleep Wake Disorders; Substance P | 2014 |
Pain and microcrystalline arthritis.
Topics: Animals; Arthritis, Gouty; Calcium Pyrophosphate; Chronic Pain; Crystallization; Dinoprostone; Disease Models, Animal; Humans; Inflammation Mediators; Interleukin-1beta; Kinins; Musculoskeletal Pain; Nociceptors; Osteoarthritis; Quality of Life; Rats; Substance P; TRPV Cation Channels; Uric Acid | 2014 |
An evolutionary stress-response hypothesis for chronic widespread pain (fibromyalgia syndrome).
Topics: Animals; Biological Evolution; Central Nervous System Sensitization; Chronic Pain; Fibromyalgia; Humans; Nociception; Receptors, Neurokinin-1; Stress, Psychological; Substance P | 2011 |
Understanding the fibromyalgia syndrome.
Topics: Animals; Chronic Pain; Fibromyalgia; Humans; Hypothalamo-Hypophyseal System; Neuroimaging; Pituitary-Adrenal System; Serotonin; Substance P; Syndrome | 2007 |
1 trial(s) available for substance p and Chronic Pain
| Article | Year |
|---|---|
Effects of Acupressure on Pain, Flexibility, and Substance P in Middle-Age Women with Chronic Neck Pain.
Topics: Acupressure; Adult; Chronic Pain; Female; Humans; Middle Aged; Neck Pain; Pain Measurement; Range of Motion, Articular; Substance P; Treatment Outcome | 2021 |
19 other study(ies) available for substance p and Chronic Pain
| Article | Year |
|---|---|
Ultra-Low Frequency Transcutaneous Electrical Nerve Stimulation on Pain Modulation in a Rat Model with Myogenous Temporomandibular Dysfunction.
Topics: Animals; Chronic Pain; Disease Models, Animal; Electromyography; Electrophysiological Phenomena; Masticatory Muscles; Motor Endplate; Myofascial Pain Syndromes; Parabrachial Nucleus; Proto-Oncogene Proteins c-fos; Rats; Receptors, Opioid, mu; Substance P; Temporomandibular Joint Disorders; Transcutaneous Electric Nerve Stimulation | 2021 |
Effect of NSAIDs Supplementation on the PACAP-, SP- and GAL-Immunoreactive Neurons in the Porcine Jejunum.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Enteric Nervous System; Female; Galanin; Jejunum; Neurons; Pituitary Adenylate Cyclase-Activating Polypeptide; Substance P; Swine | 2021 |
New Engineered-Botulinum Toxins Inhibit the Release of Pain-Related Mediators.
Topics: Animals; Botulinum Toxins; Cell Survival; Chronic Pain; Cytokines; Macrophages; Mice; Neuropeptides; Peptide Hydrolases; Protein Engineering; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Sensory Receptor Cells; Substance P; Vesicle-Associated Membrane Protein 1; Vesicle-Associated Membrane Protein 3 | 2019 |
Continuous infusion of substance P into rat striatum relieves mechanical hypersensitivity caused by a partial sciatic nerve ligation via activation of striatal muscarinic receptors.
Topics: Animals; Chronic Pain; Corpus Striatum; Hyperalgesia; Male; Neuralgia; Nociception; Pain Measurement; Peripheral Nerve Injuries; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Neurokinin-1; Sciatic Nerve; Sciatic Neuropathy; Substance P | 2020 |
Increased substance P-like immunoreactivities in parabrachial and amygdaloid nuclei in a rat model with masticatory myofascial pain.
Topics: Amygdala; Animals; Chronic Pain; Myofascial Pain Syndromes; Nociception; Rats; Substance P | 2020 |
The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain.
Topics: Amides; Analgesics; Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice, Inbred ICR; Neuralgia; Pain Threshold; Peptide Fragments; Receptors, Opioid, mu; Substance P | 2021 |
Effect of band and knife castration of beef calves on welfare indicators of pain at three relevant industry ages: II. Chronic pain.
Topics: Animal Welfare; Animals; Behavior, Animal; Body Weight; Cattle; Chronic Pain; Hair; Haptoglobins; Hydrocortisone; Male; Orchiectomy; Pain Measurement; Random Allocation; Saliva; Stress, Physiological; Substance P | 2017 |
Mu-opioid receptors in nociceptive afferents produce a sustained suppression of hyperalgesia in chronic pain.
Topics: Animals; Calcitonin Gene-Related Peptide; Chronic Pain; Hyperalgesia; Male; Mice; Mice, Transgenic; Neurons, Afferent; Pain Measurement; Receptors, Opioid, mu; Substance P | 2018 |
Involvement of Substance P in the Analgesic Effect of Low-Level Laser Therapy in a Mouse Model of Chronic Widespread Muscle Pain.
Topics: Acids; Animals; Capsaicin; Chronic Pain; Cnidarian Venoms; Disease Models, Animal; Dose-Response Relationship, Drug; Fibromyalgia; Laser Therapy; Low-Level Light Therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Musculoskeletal Pain; Protein Precursors; Signal Transduction; Substance P; Tachykinins; TRPV Cation Channels | 2019 |
Possible inflammatory pain biomarkers in postamputation pain.
Topics: Adult; Aged; Amputees; Biomarkers; Calcitonin Gene-Related Peptide; Chronic Pain; Humans; Hyperalgesia; Middle Aged; Pain Measurement; Phantom Limb; Substance P | 2019 |
Chemokine profile of disc degeneration with acute or chronic pain.
Topics: Acute Pain; Adolescent; Adult; Chemokines; Chronic Pain; Female; Humans; Interleukin-1alpha; Intervertebral Disc Degeneration; Intervertebral Disc Displacement; Male; Matrix Metalloproteinase 3; Middle Aged; Substance P; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Young Adult | 2013 |
Do low levels of beta-endorphin in the cerebrospinal fluid indicate defective top-down inhibition in patients with chronic neuropathic pain? A cross-sectional, comparative study.
Topics: Adult; Analgesics; beta-Endorphin; Biomarkers; Chronic Pain; Clinical Trials as Topic; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Neuralgia; Pain, Intractable; Pain, Postoperative; Substance P | 2014 |
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Acids; Formaldehyde; Glutamic Acid; Hyperalgesia; Ischemia; Ketanserin; Male; Mice; Monoterpenes; Neuralgia; Pain, Postoperative; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Stomach Ulcer; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Acid mediates a prolonged antinociception via substance P signaling in acid-induced chronic widespread pain.
Topics: Acid Sensing Ion Channels; Acids; Animals; Capsaicin; Chronic Pain; Cnidarian Venoms; Disease Models, Animal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Pain Measurement; Signal Transduction; Substance P; TRPV Cation Channels | 2014 |
Antinociceptive effects of endomorphin-2: suppression of substance P release in the inflammatory pain model rat.
Topics: Animals; Arthritis, Experimental; Chronic Pain; Ganglia, Spinal; Hyperalgesia; Injections, Spinal; Male; Microdialysis; Microscopy, Electron; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nociception; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Receptors, Presynaptic; Spinal Cord; Spinal Cord Dorsal Horn; Stress, Mechanical; Substance P; Tryptophan | 2015 |
Substance P and Chronic Pain in Patients with Chronic Inflammation of Connective Tissue.
Topics: Arthritis, Rheumatoid; Chronic Pain; Connective Tissue; Female; Humans; Inflammation; Male; Middle Aged; Osteoarthritis; Substance P; Synovial Fluid; Synovial Membrane | 2015 |
Nanoemulsion Thermoreversible Pluronic F127-Based Hydrogel Containing Hyptis pectinata (Lamiaceae) Leaf Essential Oil Produced a Lasting Anti-hyperalgesic Effect in Chronic Noninflammatory Widespread Pain in Mice.
Topics: Analgesics; Animals; Chronic Pain; Disease Models, Animal; Hydrogel, Polyethylene Glycol Dimethacrylate; Lamiaceae; Male; Mice; Oils, Volatile; Pain Measurement; Periaqueductal Gray; Plant Extracts; Proto-Oncogene Proteins c-fos; Spinal Cord; Substance P | 2018 |
An antinociceptive role for substance P in acid-induced chronic muscle pain.
Topics: Acid Sensing Ion Channels; Action Potentials; Analgesics; Animals; Chronic Pain; Electrophysiology; Ganglia, Spinal; Gene Deletion; Mice; Mice, Inbred C57BL; Musculoskeletal Pain; Neurokinin A; Neurokinin-1 Receptor Antagonists; Pain Measurement; Patch-Clamp Techniques; Protein Precursors; Receptors, Neurokinin-1; Sodium Channels; Substance P; Tachykinins | 2012 |
Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain.
Topics: Acute Pain; Animals; Chronic Pain; Gene Expression Regulation; Inflammation Mediators; Keratinocytes; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Substance P | 2012 |