Page last updated: 2024-08-23

substance p and Chronic Disease

substance p has been researched along with Chronic Disease in 185 studies

Research

Studies (185)

TimeframeStudies, this research(%)All Research%
pre-199012 (6.49)18.7374
1990's60 (32.43)18.2507
2000's73 (39.46)29.6817
2010's33 (17.84)24.3611
2020's7 (3.78)2.80

Authors

AuthorsStudies
Boyvadoglu, C; Inaloz, HS; Korkmaz, P; Ozaydin-Yavuz, G; Taysı, S; Ulusal, H; Yavuz, IH1
Metz, M1
Duan, XH; Huang, YZ; Liu, WL; Su, KH; Wang, T; Yan, YF; Yang, L1
Belzberg, M; Huang, AH; Kwatra, SG; Williams, KA1
Boodhoo, K; Myburgh, KH; Tabb, DL; van de Vyver, M; Vlok, M1
Eirefelt, S; Hawro, T; Hoey, G; Koopmann, W; Maurer, M; Metz, M; Ohanyan, T; Schoepke, N1
He, S; Wang, W; Zhang, H; Zheng, W1
Liu, L; Sun, T; Wang, L; Zhang, L1
Capizzi, A; Ghezzi, M; Rossi, GA; Sacco, O; Silvestri, M1
Doche, I; Ericson, M; Hordinsky, MK; McAdams, BD; Romiti, R; Valente, NS; Wilcox, GL1
Arrigo, M; Beauvais, F; Cohen-Solal, A; Launay, JM; Logeart, D; Nougué, H; Pezel, T; Picard, F; Sadoune, M; Vodovar, N1
Bumanglag, AV; Burke, SN; Chun, E; Sloviter, RS1
Ständer, S; Yosipovitch, G1
Asano, T; Fukumitsu, K; Hijikata, H; Kamiya, T; Kanemitsu, Y; Kubota, E; Niimi, A; Suzuki, M; Takeda, N; Takemura, M; Ueda, T; Yamaba, Y1
Fayne, RA; Hashimoto, T; Kursewicz, CD; Nanda, S; Nattkemper, L; Shah, SM; Yokozeki, H; Yosipovitch, G1
Rees, JD; Scott, A; Stride, M1
Dombrowski, F; Heidecke, CD; Kessler, W; Partecke, LI; Schmidt-Wankel, F; Thiele, A; von Bernstorff, W; Wodny, M1
Chen, JW; Fu, WQ; Guo, LL; Jiang, Y; Liu, N; Murao, K; Shang, J; Wang, GQ; Wang, LH; Zhang, GX; Zhou, XP1
Chun, J; Khan, S; Kim, YS; Shehzad, O1
Groffik, A; Hawro, T; Krull, C; Maurer, M; Metz, M; Saluja, R; Stanger, C; Staubach, P1
Lotts, T; Ständer, S1
Ma, Y; Men, B; Shen, BQ; Sun, ZX; Wang, ZL1
Fujisawa, D; Fujitani, Y; Hayama, K; Kashiwakura, J; Kikukawa, Y; Kita, H; Kuroda, K; Nunomura, S; Okayama, Y; Ra, C; Sasaki-Sakamoto, T; Terui, T1
Başak, PY; Buyukbayram, HI; Erturan, I; Kazanoglu, OO; Vural, H1
Bäckryd, E; Gerdle, B; Ghafouri, B; Ghafouri, N; Karlsson, L; Larsson, B; Olausson, P1
Liu, YJ; Song, GH; Zhang, C1
Barry, DM; Chen, XJ; Chen, ZF; Li, H; Li, YQ; Liu, XT; Liu, XY; Munanairi, A; Shen, KF; Sun, YG; Wu, ZY; Yin, J1
He, S; Wang, J; Xu, C; Zheng, W; Zhu, W1
Barrett, KE; Camilleri, M; Sellin, JH1
Agelopoulos, K; Loser, K; Lotts, T; Luger, TA; Phan, NQ; Schmaus, G; Ständer, S1
Diraman, E; Lütfioğlu, M; Odyakmaz, S; Pamuk, F; Sakallioğlu, EE; Sakallioğlu, U1
Altdorfer, K; Fehér, E; Pongor, E; Sipos, G; Sipos, P1
da Costa, ED; Paiva, ES; Scheinberg, M1
Hattori, N; Miyamoto, N; Mochizuki, H; Tanaka, R; Urabe, T; Zhang, N1
Seybold, VS1
Coleman, CG; Lessard, A; Pickel, VM1
Chen, ZW; Li, LK; Li, WB; Liu, LM; Lu, GS; Pan, JH; Song, B; Xiong, EQ; Yang, Z; Zhang, H; Zhang, JH; Zhou, ZS1
Böhm, M; Capellino, S; Haas, S; Luger, TA; Phan, NQ; Ständer, S; Straub, RH1
Chung, JW; Chung, SC; Jang, MU; Kho, HS; Park, JW1
Alesci, S; Bonne, O; Charney, DS; Collins, C; Gill, JM; Kinkead, B; Luckenbaugh, DA; Manji, HK; Neumeister, A; Owens, MJ; Vythilingam, M; Yuan, P1
Chow, CW; Farmer, PJ; Hutson, JM; King, SK; Southwell, BR; Yik, YI1
Liu, B; Lü, H; Qiu, Z; Xu, S; Yu, L; Zhao, T1
Amiri, M; Beiraghdar, F; Davoudi, SM; Hoseininejad, SL; Kolivand, M; Panahi, Y; Sahebkar, A1
El-Nour, H; Grip, L; Holst, M; Johansson, B; Lonne-Rahm, SB; Nordlind, K; Theodorsson, E1
Harbuz, MS; Jessop, DS1
Erin, N; Eyigor, H; Eyigor, M; Gultekin, M; Osma, U; Yilmaz, MD1
Csáti, A; Kuris, A; Lukács, M; Majláth, Z; Szok, D; Tajti, J; Tuka, B; Vécsei, L1
Alpar, EK; Killampalli, VV; Onuoha, G; Waters, R1
Berghaus, A; Holzhausen, HJ; Knipping, S; Mir Salim, PA1
Bodfish, JW; Sutton, KA; Symons, FJ; Walker, C1
Liu, HX1
Lu, Y; Vera-Portocarrero, LP; Westlund, KN1
Corcoran, BM; Mayhew, IG; Prince, D1
Iadarola, MJ; Lonser, RR; Morrison, PF; Sarntinoranont, M1
El-Salhy, M1
Actor, JK; Chappell, CL; Lewis, DE; Okhuysen, PC; Robinson, P; Weinstock, JV; White, AC1
Boncz, I; Csillik, B; Janka, Z; Kálmán, J; Knyihár, E; Mihály, A; Vécsei, L1
Arsenescu, R; Blum, A; Bunnett, N; Elliott, D; Metwali, A; Weinstock, JV1
Depaulis, A; Fernandes, GA; Levy, S; Namer, IJ; Ruocco, HH1
Cho, YS; Lee, CK; Moon, HB; Park, SY; Yoo, B1
Fang, MR; Huang, ZJ; Lin, M; Pang, ZJ; Wu, JS; Yan, HD; Zhou, JF1
Weinstock, JV1
Alaçam, T; Oral, B; Tuncer, LI1
Chen, JG; Guan, BC; Li, ZW; Liu, CJ; Wu, ZZ; Yang, Q1
Catto-Smith, T; Chase, J; Djaja, S; Farmer, P; Gibb, S; Hutson, JM; King, S; Ong, SY; Shin, YM; Southwell, B; Stanton, M; Sutcliffe, J1
Arcari, ML; Ballabeni, V; Barocelli, E; Bertoni, S; Gabella, G; Ghizzardi, P; Impicciatore, M; Lagrasta, C1
Nakano, Y1
Gao, H; Han, D; Peng, S; Zhang, H; Zhu, X1
Hayashida, Y; Hirakawa, H; Kawakami, T; Kusakabe, T; Matsuda, H; Oikawa, S; Takenaka, T1
Bartfai, T; Fetissov, S; Gaudet, L; Hökfelt, T; Jimenez, PA; Mathé, AA; Moreau, JL; Mortas, P; Sergeyev, V1
Asero, R; Lorini, M; Tedeschi, A1
Riley, G1
El-Raziky, M; El-Raziky, MS; Gohar, N1
He, ZJ; Pasricha, PJ; Shenoy, M; Winston, JH; Xiao, SY1
Kreider, RA; Rothman, SM; Winkelstein, BA1
Toru, M1
Hayashida, Y; Hirakawa, H; Kusakabe, T; Matsuda, H; Oikawa, S2
Gutkin, DW; Pezzone, MA; Ustinova, EE1
Dickenson, AH; Hunt, S; Rahman, W; Rygh, LJ; Sandhu, H; Suzuki, R; Vonsy, JL; Webber, M; Wong, Y1
Fabry, Z; Johnson, MJ; Karman, J; Lee, J; Ling, C; Reinke, EK; Sandor, M; Weinstock, JV1
Al-Mutawaly, N; Bercik, P; Blennerhassett, PA; Collins, SM; Ghia, JE; Verdu, EF; Verma-Gandhu, M1
Bady, P; Baumann, T; Bigliardi, PL; Bigliardi-Qi, M; Gaveriaux-Ruff, C; Kieffer, BL; Pfaltz, K; Rufli, T1
Dömötör, A; Hunyady, B; Kereskay, L; Mózsik, G; Szekeres, G; Szolcsányi, J1
Lonne-Rahm, S; Nordlind, K; Remröd, C1
Song, B; Zhang, SW; Zhou, ZS1
Alfredson, H; Andersson, G; Danielson, P; Forsgren, S1
Bianchi, M; Ferrario, P; Franchi, S; Sacerdote, P; Sotgiu, ML1
Peterson, EL1
Rosenkranz, MA1
Jang, JE; Jung, JS; Kwon, MS; Lee, JK; Park, SH; Seo, YJ; Shim, EJ; Suh, HW1
Kozlova, IV; Volkov, SV1
Akcali, C; Aynacioglu, AS; Benlier, N; Erbagci, Z; Ozkur, M1
Jiang, SH; Lou, XF; Pang, LX; Shi, XM; Tu, WZ; Yang, GH; Zhang, RF1
Kenyon, JN; Lewith, GT1
Albuquerque, RH; Bannister, R; Barnes, AJ; Bishop, AE; Bloom, SR; Long, RG; McGregor, GP; O'Shaughnessy, DJ; Polak, JM1
Boni, B; Casacchia, M; Cerbo, R; Corona, R1
Fields, HL; Levine, JD1
Chowdrey, HS; Harbuz, MS; Jessop, DS; Larsen, PJ; Lightman, SL1
Hayrinen-Immonen, RH; Hukkanen, M; Konttinen, YT; Malmstrom, MJ; Nordstrom, D; Polak, J; Sorsa, T1
Alvarez, C; Brecha, NC; De Giorgio, R; Go, VL; Reber, HA; Sternini, C; Widdison, AL1
Boudouresque, F; Giraud, P; Guieu, R; Tardy-Gervet, MF1
Archer, SL; Hampl, V; Isaacson, TC; Nelson, DP; Weir, EK1
Hersh, EV; Ochs, HA; Pertes, RA1
Besson, JM; Calvino, B; Couraud, JY1
Hirayama, Y; Ichinose, M; Miura, M; Nakajima, N; Shirato, K; Tomaki, M; Yamauchi, H1
Chen, CF; Chien, CT; Lai, YL; Shiao, HL; Thacker, AA; Zhang, HQ1
Luts, A; Pilmane, M; Sundler, F1
Cornefjord, M; Farley, DB; Olmarker, K; Rydevik, B; Weinstein, JN1
Chiarenza, AP; Elverdin, JC; Frid, AB; Giglio, MJ1
Qiao, J; Tao, Z; Xiao, J; Zhao, C; Zhao, S1
Goldin, E; Karmeli, F; Lysy, J1
Giraud, P; Guieu, R; Tardy-Gervet, MF1
Johnson, BW; Kambam, JR; Naukam, RJ; Parris, WC; Sastry, BV1
Blackwell, JM; Chowdrey, HS; Harbuz, MS; Jessop, DS; Larsen, PJ; Lightman, SL1
Killingsworth, CR; Paulauskis, JD; Shore, SA1
Kajander, KC; Pollock, CH; Xu, J1
Carney, AS; Jones, NS1
Gingras, JL; Long, WA; Segreti, T; Wasserstein, M1
Hutson, JM1
Aloe, L; Angelucci, F; Fiore, M; Moroni, R1
Dalmaz, Y; Denoroy, L; Jouvet, M; Pequignot, JM; Poncet, L1
Rees, S; Tolcos, M1
Ellisman, MH; Kawakami, T; Kusakabe, T; Powell, FL; Sawada, H; Takenaka, T1
Didion, SP; Mayhan, WG1
Catto-Smith, AG; Chow, CW; Hurley, MR; Hutson, JM; Uemura, S; Wheatley, JM1
Chen, CF; Chen, LW; Chien, CT; Wu, MS1
Carlsöö, B; Lidegran, M; Midvedt, T; Nilsson, L; Norlander, T; Rivero, C; Stierna, P1
Caramori, G; Ciaccia, A; Fabbri, L; Facchini, F; Lucchini, RE; Maestrelli, P; Mapp, CE; Polak, JM; Saetta, M; Springall, DR; Turato, G1
Brodin, E; Delander, GE; Fredholm, BB; Schött, E1
Figueroa, JM; Mansilla, E; Suburo, AM1
Lai, LC; Lai, YL; Lin, CW1
Franke, S; Hein, G; Kluge, H; Sprott, H1
Adler, G; Ernst, S; Eysselein, VE; Flämig, G; Geerling, I; Reinshagen, M; Walsh, JH; Wong, H1
Bousquet, J; Chanez, P; Godard, P; Moradoghi-Hattvani, A; Polak, JM; Springall, D; Vignola, AM1
Luo, F1
Baluk, P; Lindsey, JR; McDonald, DM; Murphy, TJ; Thurston, G1
Chen, CF; Lai, YL; Wu, HD1
Hoheisel, U; Kaske, A; Mense, S1
Altomare, DF; Genualdo, M; Mansi, G; Memeo, V; Mitolo, CI; Mitolo-Chieppa, D; Montagnani, M; Potenza, MA; Rinaldi, M; Rinaldi, R; Serio, M1
Helme, RD; Khalil, Z; Liu, T1
Benoliel, R; Caudle, RM; Eliav, E; Iadarola, MJ; Leeman, S; Mannes, AJ1
Borici-Mazi, R; Kontou-Fili, K; Kouridakis, S1
Calvino, B; Grannec, G; Onténiente, B; Pezet, S1
Basbaum, AI1
Andersson, B; Gillquist, J; Messner, K; Räsänen, T; Wei, Y1
de Souza, RR; Liberti, EA; Maifrino, LB1
Friedrich, MJ1
Hayashida, Y; Kawakami, T; Kusakabe, T; Matsuda, H; Takenaka, T1
Baccante, G; Büchler, MW; Di Febbo, C; di Mola, FF; Di Sebastiano, P; Friess, H; Innocenti, P; Porreca, E1
Rau, CL; Russell, IJ1
Hietanen, J; Hukkanen, M; Konttinen, YT; Malmström, M; Nissalo, S; Polak, J1
Jüsten, HP; Miller, LE; Schölmerich, J; Straub, RH1
Kaneko, M; Kawakita, T; Kuraishi, Y; Maekawa, T; Miyamoto, T; Nishikawa, Y; Nojima, H; Yamaguchi, T1
Baluk, P; Gómez, AD; Hashizume, H; Kwan, ML; McDonald, DM1
Echizen, H; Fukatsu, T; Hashiguchi, M; Itoh, T; Kariya, S; Nishimura, E; Odanaka, J; Ohtani, M; Okumura, H; Rikihisa, T; Takahashi, T; Uchino, K; Watanabe, K1
Yonehara, N; Yoshimura, M1
Goldin, E; Granot, E; Karmeli, F; Lysy, J; Waldbaum, C; Wengrower, D1
Corbett, AD; McKee, R; Menzies, JR1
Alberti, A; Floridi, A; Gallai, V; Sarchielli, P1
Boulos, P; Davis MSc, C; Gabella, G; Herrick, SE; Laurent, GJ; Mutsaers, SE; Sulaiman, H1
Kastin, AJ; Martin-Schild, S; Smith, RR; Zadina, JE1
Abrams, GA; Bentley, E; Campbell, S; Marfurt, CF; McDermott, A; Murphy, CJ; Reid, TW1
Chen, S; Song, Z; Wu, J; Zhang, J1
Chen, CF; Chu, SJ; Lai, YL; Ma, MC1
Brakch, N; Cavadas, C; Giger, R; Grouzmann, E; Lacroix, JS; Landis, B; Malis, D; Monod, M; Morel, DR; Nicoucar, K; Szalay-Quinodoz, I; Wilk, S1
Chen, CF; Chien, CT; Huang, HS; Ma, MC; Wu, MS1
Aanonsen, LM; Bennett, GJ; Kajander, KC; Seybold, VS1
Cimitan, A; Fantini, F; Giannetti, A; Pincelli, C1
Atkinson, B; Foreman, JC; Hayes, N; Lee, TH; Morris, RW; Smith, CH1
Beger, HG; Bockman, E; Büchler, M; Friess, H; Malfertheiner, P; Müller, S; Nohr, D; Weihe, E1
Holmdahl, R; Nyberg, F; Persson, S; Post, C1
Aldskogius, H; Kinnman, E1
Butovskaia, ML; Deriagina, MA; Startsev, VG1
Zhang, ZB1
Albe-Fessard, D; Iwayama, K; Kurihara, M; Mori, K; Niwa, M; Tasker, RR; Yamashiro, K1
Molina, E1
Almay, BG; Johansson, F; Sakurada, T; Terenius, L; von Knorring, L1
Brodin, E; Linderoth, B; Meyerson, BA1
Carney, JA; Go, L; Go, VL; Koch, TR1
Hunt, S; Wells, C; Williams, S1
Almay, BGL; Johansson, F; Le Grevés, P; Terenius, L; Von Knorring, L1
Butolin, EG; Danilov, GE; Ibatov, AD; Isakov, LS1
Adrian, TE; Bloom, SR; Domschke, S; Domschke, W; Lux, G1
Goldin, E; Karmeli, F; Rachmilewitz, D; Selinger, Z1

Reviews

21 review(s) available for substance p and Chronic Disease

ArticleYear
Prurigo nodularis: Pathogenesis and management.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:6

    Topics: Administration, Cutaneous; Administration, Oral; Antidepressive Agents; Antipruritics; Biopsy; Calcitonin Gene-Related Peptide; Chronic Disease; Diagnosis, Differential; Humans; Immunosuppressive Agents; Medical History Taking; Nerve Tissue Proteins; Neural Pathways; Phototherapy; Prurigo; Randomized Controlled Trials as Topic; Receptors, Nerve Growth Factor; Severity of Illness Index; Skin; Substance P; Therapies, Investigational; Treatment Outcome

2020
Substance P and neurokinin 1 receptor are new targets for the treatment of chronic pruritus.
    The British journal of dermatology, 2019, Volume: 181, Issue:5

    Topics: Animals; Chronic Disease; Clinical Trials, Phase II as Topic; Disease Models, Animal; Humans; Molecular Targeted Therapy; Neurokinin-1 Receptor Antagonists; Pruritus; Quality of Life; Receptors, Neurokinin-1; Severity of Illness Index; Signal Transduction; Skin; Substance P; Treatment Outcome

2019
Tendons--time to revisit inflammation.
    British journal of sports medicine, 2014, Volume: 48, Issue:21

    Topics: Anti-Inflammatory Agents; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Musculoskeletal Pain; Neovascularization, Pathologic; Substance P; Tendinopathy; Tendons; Tumor Necrosis Factor-alpha

2014
Research in practice: substance P antagonism in chronic pruritus.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2014, Volume: 12, Issue:7

    Topics: Anti-Inflammatory Agents; Chronic Disease; Cytokines; Dermatologic Agents; Evidence-Based Medicine; Humans; Models, Immunological; Pruritus; Skin; Substance P

2014
Pathophysiology, Evaluation, and Management of Chronic Watery Diarrhea.
    Gastroenterology, 2017, Volume: 152, Issue:3

    Topics: C-Reactive Protein; Chromogranins; Chronic Disease; Diarrhea; Feces; Gastrointestinal Motility; Humans; Inflammation; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Intestines; Irritable Bowel Syndrome; Lactoferrin; Leukocyte L1 Antigen Complex; Osmolar Concentration; Permeability; Prostaglandins; Serotonin; Substance P

2017
Fibromyalgia: an update and immunological aspects.
    Current pain and headache reports, 2008, Volume: 12, Issue:5

    Topics: Antibodies; Autoantibodies; Chronic Disease; Evoked Potentials, Somatosensory; Fibromyalgia; Headache; Humans; Interleukin-2; Neural Pathways; Nociceptors; Pain Threshold; Polymers; Posterior Horn Cells; Psychophysiologic Disorders; Substance P

2008
The role of peptides in central sensitization.
    Handbook of experimental pharmacology, 2009, Issue:194

    Topics: Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Central Nervous System; Chronic Disease; Gene Expression Regulation; Humans; Hyperalgesia; Ligands; Neurons; Pain; Pain Threshold; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Substance P; Synaptic Transmission; Transcription Factors

2009
Stress and inflammatory disease: widening roles for serotonin and substance P.
    Stress (Amsterdam, Netherlands), 2001, Volume: 4, Issue:1

    Topics: Acute Disease; Animals; Chronic Disease; Humans; Hypothalamo-Hypophyseal System; Inflammation; Inflammation Mediators; Pituitary-Adrenal System; Serotonin; Stress, Physiological; Stress, Psychological; Substance P

2001
[Botulinum neurotoxin--a therapy in migraine].
    Ideggyogyaszati szemle, 2012, Mar-30, Volume: 65, Issue:3-4

    Topics: Acute Disease; Analgesics; Botulinum Toxins, Type A; Calcitonin Gene-Related Peptide; Chronic Disease; Clinical Trials, Phase III as Topic; Glutamic Acid; Humans; Migraine Disorders; SNARE Proteins; Substance P; Synaptosomal-Associated Protein 25; Treatment Outcome

2012
The role of substance P, hemokinin and their receptor in governing mucosal inflammation and granulomatous responses.
    Frontiers in bioscience : a journal and virtual library, 2004, May-01, Volume: 9

    Topics: Animals; Chronic Disease; Gastroenteritis; Granuloma; Hepatitis; Humans; Immunity, Mucosal; Inflammation; Inflammatory Bowel Diseases; Mice; Protein Precursors; Receptors, Neurokinin-1; Substance P; Tachykinins

2004
Chronic constipation: no longer stuck! Characterization of colonic dysmotility as a new disorder in children.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:6

    Topics: Adult; Child, Preschool; Chronic Disease; Colectomy; Colon; Colostomy; Constipation; Electric Stimulation Therapy; Enema; Female; Gastrointestinal Motility; Humans; Infant; Male; Manometry; Monitoring, Ambulatory; Multiple Endocrine Neoplasia Type 2b; Neurons; Nitric Oxide Synthase; Proto-Oncogene Proteins c-kit; Substance P; Vasoactive Intestinal Peptide

2004
Chronic tendon pathology: molecular basis and therapeutic implications.
    Expert reviews in molecular medicine, 2005, Mar-24, Volume: 7, Issue:5

    Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Collagen; Cumulative Trauma Disorders; Extracellular Matrix; Glycoproteins; Humans; Matrix Metalloproteinases; Middle Aged; Neuropeptides; Proteoglycans; Rupture; Substance P; Tendinopathy; Tendon Injuries; Tendons

2005
[Brain of patients with chronic schizophrenia and neurotransmitters].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2005, Volume: 107, Issue:10

    Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Humans; Neurotransmitter Agents; Receptors, Dopamine D2; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Substance P; Tyrosine 3-Monooxygenase

2005
Fibromyalgia--management of a misunderstood disorder.
    Journal of the American Academy of Nurse Practitioners, 2007, Volume: 19, Issue:7

    Topics: Anticonvulsants; Antidepressive Agents; Causality; Chronic Disease; Diagnosis, Differential; Exercise; Fibromyalgia; Humans; Hypothalamo-Hypophyseal System; Medical History Taking; Neuromuscular Agents; Nurse Practitioners; Nurse's Role; Nursing Assessment; Patient Care Planning; Patient Education as Topic; Physical Examination; Pituitary-Adrenal System; Primary Health Care; Serotonin; Social Support; Substance P; United States

2007
Substance P at the nexus of mind and body in chronic inflammation and affective disorders.
    Psychological bulletin, 2007, Volume: 133, Issue:6

    Topics: Adrenal Medulla; Asthma; Chronic Disease; Humans; Hypothalamo-Hypophyseal System; Inflammation; Mood Disorders; Pituitary-Adrenal System; Psychophysiology; Substance P

2007
Physiological and psychological explanations for the mechanism of acupuncture as a treatment for chronic pain.
    Social science & medicine (1982), 1984, Volume: 19, Issue:12

    Topics: Acupuncture Therapy; Animals; Chronic Disease; Electric Stimulation Therapy; Endorphins; Humans; Hypnosis; Nervous System; Pain; Pain Management; Periaqueductal Gray; Placebos; Raphe Nuclei; Rats; Reflex; Substance P; Thalamus

1984
Pain--mechanics and management.
    The Western journal of medicine, 1984, Volume: 141, Issue:3

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Arachidonic Acids; Autonomic Nervous System; Chronic Disease; Humans; Neurons, Afferent; Nociceptors; Pain; Pain Management; Psychotropic Drugs; Sensory Thresholds; Substance P; Sympatholytics; Transcutaneous Electric Nerve Stimulation

1984
Topical capsaicin-pharmacology and potential role in the treatment of temporomandibular pain.
    The Journal of clinical dentistry, 1994, Volume: 5, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chronic Disease; Facial Pain; Humans; Nerve Fibers; Substance P; Temporomandibular Joint Disorders

1994
Idiopathic rhinitis: idiopathic or not?
    Clinical otolaryngology and allied sciences, 1996, Volume: 21, Issue:3

    Topics: Air Pollution; Asthma; Chronic Disease; Eosinophilia; Eosinophils; Humans; Immunoglobulin E; Immunoglobulin G; Interleukin-3; Interleukin-4; Rhinitis; Substance P

1996
Distinct neurochemical features of acute and persistent pain.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jul-06, Volume: 96, Issue:14

    Topics: Acute Disease; Animals; Chronic Disease; Humans; Isoenzymes; Mice; Mice, Knockout; Neurochemistry; Neurokinin A; Pain; Protein Kinase C; Protein Precursors; Substance P; Tachykinins

1999
Is fibromyalgia a distinct clinical syndrome?
    Current review of pain, 2000, Volume: 4, Issue:4

    Topics: Autonomic Nervous System; Chronic Disease; Demography; Fibromyalgia; Humans; Neurologic Examination; Neurosecretory Systems; Nociceptors; Pain; Pain Threshold; Spinal Cord; Substance P

2000

Trials

4 trial(s) available for substance p and Chronic Disease

ArticleYear
Role of Substance P and Its Receptor Neurokinin 1 in Chronic Prurigo: A Randomized, Proof-of-Concept, Controlled Trial with Topical Aprepitant.
    Acta dermato-venereologica, 2018, Jan-12, Volume: 98, Issue:1

    Topics: Administration, Cutaneous; Aged; Aprepitant; Case-Control Studies; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Proof of Concept Study; Prospective Studies; Prurigo; Pruritus; Receptors, Neurokinin-1; Severity of Illness Index; Substance P; Visual Analog Scale

2018
Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial.
    The British journal of nutrition, 2012, Volume: 108, Issue:7

    Topics: Adult; Antioxidants; Antipruritics; Chemical Warfare Agents; Chronic Disease; Curcumin; Dietary Supplements; Double-Blind Method; Humans; Iran; Irritants; Male; Middle Aged; Mustard Gas; Oxidoreductases; Pruritus; Quality of Life; Severity of Illness Index; Substance P; Surveys and Questionnaires; Veterans

2012
Cutaneous responses to substance P and calcitonin gene-related peptide in chronic urticaria: the effect of cetirizine and dimethindene.
    Allergy, 1999, Volume: 54, Issue:1

    Topics: Adult; Calcitonin Gene-Related Peptide; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hypersensitivity, Delayed; Male; Skin Physiological Phenomena; Substance P; Urticaria

1999
Cutaneous responses to vasoactive intestinal polypeptide in chronic idiopathic urticaria.
    Lancet (London, England), 1992, Jan-11, Volume: 339, Issue:8785

    Topics: Adult; Calcitonin Gene-Related Peptide; Chronic Disease; Female; Humans; Intradermal Tests; Male; Microcirculation; Middle Aged; Neurokinin A; Skin; Substance P; Urticaria; Vasoactive Intestinal Peptide

1992

Other Studies

160 other study(ies) available for substance p and Chronic Disease

ArticleYear
Effects of Omalizumab on Serum Levels of Substance P, Calcitonin Gene-Related Peptide, Neuropeptide Y, and Interleukin-31 in Patients with Chronic Spontaneous Urticaria.
    Mediators of inflammation, 2023, Volume: 2023

    Topics: Anti-Allergic Agents; Calcitonin Gene-Related Peptide; Chronic Disease; Chronic Urticaria; Humans; Immunoglobulin E; Interleukins; Neuropeptide Y; Omalizumab; Substance P; Treatment Outcome; Urticaria

2023
Are we facing a change in the treatment of chronic pruritus?
    The British journal of dermatology, 2019, Volume: 181, Issue:5

    Topics: Chronic Disease; Humans; Pruritus; Receptors, Neurokinin-1; Substance P

2019
Effects of Zuojin pill on depressive behavior and gastrointestinal function in rats with chronic unpredictable mild stress: Role of the brain-gut axis.
    Journal of ethnopharmacology, 2020, May-23, Volume: 254

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain; Chronic Disease; Cytokines; Depression; Drugs, Chinese Herbal; Gastrins; Gastrointestinal Transit; Glucagon-Like Peptide 1; Intestine, Small; Male; Motilin; Rats, Sprague-Dawley; Stress, Psychological; Substance P; Vasoactive Intestinal Peptide

2020
Dysregulated healing responses in diabetic wounds occur in the early stages postinjury.
    Journal of molecular endocrinology, 2021, Volume: 66, Issue:2

    Topics: Animals; Body Fluids; Chronic Disease; Cytokines; Diabetes Mellitus, Experimental; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Obese; Proteome; Substance P; Wound Healing; Wounds and Injuries

2021
[Up-regulated expression of NK1R in eosinophil-enriched blood cells from patients with chronic spontaneous urticaria].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2017, Volume: 33, Issue:8

    Topics: Adult; Animals; Chronic Disease; Eosinophilia; Female; Humans; Male; Middle Aged; Neurokinin-1 Receptor Antagonists; Pollen; Pyroglyphidae; Receptors, Neurokinin-1; Substance P; Up-Regulation; Urticaria

2017
The research of the possible mechanism and the treatment for capsaicin-induced cough.
    Pulmonary pharmacology & therapeutics, 2018, Volume: 49

    Topics: Animals; Antitussive Agents; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Codeine; Cough; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Guinea Pigs; Male; Neurokinin A; Pyrrolidines; Substance P; TRPV Cation Channels; Urea

2018
Airway inflammation and injury in children with prevalent weakly acidic gastroesophageal refluxes.
    Respiratory medicine, 2018, Volume: 143

    Topics: Bronchoalveolar Lavage Fluid; Bronchoscopy; Child; Child, Preschool; Chronic Disease; Female; Gastroesophageal Reflux; Humans; Infant; Inflammation; Macrophages; Male; Pepsin A; Recurrence; Respiratory System; Respiratory Tract Diseases; Retrospective Studies; Substance P

2018
Evidence for neurogenic inflammation in lichen planopilaris and frontal fibrosing alopecia pathogenic mechanism.
    Experimental dermatology, 2020, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Biopsy; Calcitonin Gene-Related Peptide; Chronic Disease; Epidermis; Female; Humans; Immunohistochemistry; Inflammation; Lichen Planus; Lipid Metabolism; Lymphocytes; Male; Microscopy, Confocal; Middle Aged; Neurogenic Inflammation; Neuropeptides; Scalp; Scalp Dermatoses; Substance P

2020
Effects of sacubitril/valsartan on neprilysin targets and the metabolism of natriuretic peptides in chronic heart failure: a mechanistic clinical study.
    European journal of heart failure, 2019, Volume: 21, Issue:5

    Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Atrial Natriuretic Factor; Biphenyl Compounds; CD146 Antigen; Chronic Disease; Dose-Response Relationship, Drug; Drug Combinations; Echocardiography; Female; Fructosamine; Glucagon-Like Peptide 1; Heart Failure; Humans; Interleukin-1 Receptor-Like 1 Protein; Male; Middle Aged; Natriuretic Peptide, Brain; Neprilysin; Peptide Fragments; Substance P; Tetrazoles; Treatment Outcome; Troponin I; Valsartan

2019
Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats.
    Epilepsia, 2019, Volume: 60, Issue:5

    Topics: Animals; Chronic Disease; Dentate Gyrus; Epilepsy, Temporal Lobe; GABAergic Neurons; gamma-Aminobutyric Acid; Hippocampus; Male; Parvalbumins; Rats; Rats, Sprague-Dawley; Saporins; Sclerosis; Substance P

2019
Effect of anti-reflux treatment on gastroesophageal reflux-associated chronic cough: Implications of neurogenic and neutrophilic inflammation.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2020, Volume: 57, Issue:11

    Topics: Adult; Aged; Chronic Disease; Cough; Female; Gastroesophageal Reflux; Humans; Inflammation; Leukocyte Count; Male; Middle Aged; Neutrophils; Prospective Studies; Proton Pump Inhibitors; Rabeprazole; Severity of Illness Index; Sputum; Substance P; Treatment Outcome; Visual Analog Scale

2020
Pathophysiologic mechanisms of itch in bullous pemphigoid.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Basophils; Cell Adhesion Molecules; Chronic Disease; Cytokines; Eosinophils; Female; Fluorescent Antibody Technique; Humans; Interleukin-13; Male; Middle Aged; Oncostatin M Receptor beta Subunit; Pemphigoid, Bullous; Pruritus; Receptors, Interleukin; Receptors, Neurokinin-1; Severity of Illness Index; Skin; Substance P; Th2 Cells

2020
Appendicopathy--a clinical and diagnostic dilemma.
    International journal of colorectal disease, 2013, Volume: 28, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Appendectomy; Appendicitis; Appendix; Child; Chronic Disease; Female; Humans; Immunohistochemistry; Laparoscopy; Male; Middle Aged; S100 Proteins; Substance P; Vasoactive Intestinal Peptide; Young Adult

2013
Chronic restraint stress inhibits hair growth via substance P mediated by reactive oxygen species in mice.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Animals; Antioxidants; Chronic Disease; Corticosterone; Dermis; Glutathione Peroxidase; Hair; Hair Follicle; Male; Mast Cells; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Oxidative Stress; Reactive Oxygen Species; Receptors, Neurokinin-1; Restraint, Physical; Stress, Psychological; Substance P; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Weight Gain

2013
Mechanism underlying anti-hyperalgesic and anti-allodynic properties of anomalin in both acute and chronic inflammatory pain models in mice through inhibition of NF-κB, MAPKs and CREB signaling cascades.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Acute Disease; Adenosine Triphosphate; Analgesics; Animals; Chronic Disease; Coumarins; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hyperalgesia; Inflammation; Liver; Male; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Pain; Signal Transduction; Substance P; Time Factors; Tumor Necrosis Factor-alpha

2013
Substance P is upregulated in the serum of patients with chronic spontaneous urticaria.
    The Journal of investigative dermatology, 2014, Volume: 134, Issue:11

    Topics: Anxiety; Biomarkers; Chronic Disease; Depression; Disease Progression; Germany; Humans; Quality of Life; Severity of Illness Index; Substance P; Up-Regulation; Urticaria

2014
[Common TCM syndrome pattern of chronic pelvic pain syndrome relates to plasma substance p and beta endorphin].
    Zhonghua nan ke xue = National journal of andrology, 2014, Volume: 20, Issue:4

    Topics: beta-Endorphin; Case-Control Studies; Chronic Disease; Humans; Male; Medicine, Chinese Traditional; Pelvic Pain; Prostatitis; Substance P; Syndrome

2014
Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria.
    The Journal of allergy and clinical immunology, 2014, Volume: 134, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cells, Cultured; Chronic Disease; Eosinophil Granule Proteins; Female; Humans; Male; Mast Cells; Middle Aged; Molecular Targeted Therapy; Nerve Tissue Proteins; Protein Binding; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Skin; Skin Tests; Substance P; Up-Regulation; Urticaria; Vasoactive Intestinal Peptide; Young Adult

2014
Effects of loratadine and cetirizine on serum levels of neuropeptides in patients with chronic urticaria.
    International journal of dermatology, 2014, Volume: 53, Issue:12

    Topics: Adolescent; Adult; Calcitonin Gene-Related Peptide; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Nerve Growth Factor; Neuropeptide Y; Neuropeptides; Stem Cell Factor; Substance P; Urticaria; Vasoactive Intestinal Peptide; Young Adult

2014
Intramuscular pain modulatory substances before and after exercise in women with chronic neck pain.
    European journal of pain (London, England), 2015, Volume: 19, Issue:8

    Topics: Adult; beta-Endorphin; Chronic Disease; Exercise Therapy; Female; Glutamic Acid; Humans; Hydrocortisone; Lactic Acid; Microdialysis; Middle Aged; Neck Pain; Pain Measurement; Pain Threshold; Pyruvic Acid; Shoulder Pain; Substance P; Superficial Back Muscles; Young Adult

2015
[Prostatic inflammation-induced chronic pelvic pain: Roles of substance P and c-fos in the spinal cord].
    Zhonghua nan ke xue = National journal of andrology, 2015, Volume: 21, Issue:8

    Topics: Animals; Chronic Disease; Immunohistochemistry; Male; Pelvic Pain; Prostate; Prostatitis; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord; Substance P; Syndrome; Up-Regulation

2015
Critical evaluation of the expression of gastrin-releasing peptide in dorsal root ganglia and spinal cord.
    Molecular pain, 2016, Volume: 12

    Topics: Amino Acid Sequence; Animals; Antibody Specificity; Cell Count; Cells, Cultured; Chronic Disease; Ganglia, Spinal; Gastrin-Releasing Peptide; Gene Deletion; Gene Expression Regulation; Male; Mice, Inbred C57BL; Mice, Knockout; Posterior Horn Cells; Pruritus; Receptors, Bombesin; RNA, Messenger; Spinal Cord; Substance P

2016
Upregulated expression of substance P in basophils of the patients with chronic spontaneous urticaria: induction of histamine release and basophil accumulation by substance P.
    Cell biology and toxicology, 2016, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Animals; Antibodies, Anti-Idiotypic; Basophils; Case-Control Studies; Chronic Disease; Female; Histamine Release; Humans; Leukocyte Count; Male; Mice; Middle Aged; Receptors, Neurokinin-1; Substance P; Transcriptional Activation; Up-Regulation; Urticaria; Young Adult

2016
Dihydroavenanthramide D inhibits mast cell degranulation and exhibits anti-inflammatory effects through the activation of neurokinin-1 receptor.
    Experimental dermatology, 2017, Volume: 26, Issue:8

    Topics: Animals; Calcium Signaling; Cell Line; Chronic Disease; Drug Evaluation, Preclinical; Humans; Mast Cells; ortho-Aminobenzoates; Pruritus; Rats; Receptors, Neurokinin-1; Substance P

2017
Local peptidergic innervation of gingiva in smoking and non-smoking periodontitis patients.
    Journal of periodontology, 2008, Volume: 79, Issue:8

    Topics: Adult; Alveolar Bone Loss; Biopsy; Calcitonin Gene-Related Peptide; Chronic Disease; Dental Plaque Index; Female; Gingiva; Gingival Hemorrhage; Humans; Inflammation Mediators; Male; Middle Aged; Neurogenic Inflammation; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Smoking; Substance P

2008
Correlation and immunolocalization of substance P nerve fibers and activated immune cells in human chronic gastritis.
    Anatomical record (Hoboken, N.J. : 2007), 2008, Volume: 291, Issue:9

    Topics: Antibody Specificity; Chronic Disease; Gastric Mucosa; Gastritis; Humans; Immunoassay; Microscopy, Confocal; Nerve Fibers; NF-kappa B; Poly(ADP-ribose) Polymerases; Stomach; Substance P

2008
Activation of tyrosine hydroxylase prevents pneumonia in a rat chronic cerebral hypoperfusion model.
    Neuroscience, 2009, Jan-23, Volume: 158, Issue:2

    Topics: Animals; Bacteria; Carotid Stenosis; Chronic Disease; Cilostazol; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Deglutition; Disease Models, Animal; Dopamine; Enzyme Activation; Fibrinolytic Agents; Gene Expression Regulation; Ligation; Male; Pneumonia; Rats; Rats, Wistar; Regional Blood Flow; Substance P; Substantia Nigra; Tetrazoles; Time Factors; Tyrosine 3-Monooxygenase

2009
Chronic intermittent hypoxia reduces neurokinin-1 (NK(1)) receptor density in small dendrites of non-catecholaminergic neurons in mouse nucleus tractus solitarius.
    Experimental neurology, 2010, Volume: 223, Issue:2

    Topics: Animals; Catecholamines; Chronic Disease; Dendrites; Fluorescent Antibody Technique; Hypoxia, Brain; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; Neuronal Plasticity; Neurons; Receptors, Neurokinin-1; Reflex; Respiratory Mechanics; Sleep Apnea Syndromes; Solitary Nucleus; Substance P; Sympathetic Nervous System; Trigeminal Nucleus, Spinal; Tyrosine 3-Monooxygenase

2010
[Correlation between activation of L5-S2 spinal cord astrocytes and effect of substance P in chronic prostatitis pain].
    Zhonghua nan ke xue = National journal of andrology, 2009, Volume: 15, Issue:11

    Topics: Animals; Astrocytes; Chronic Disease; Male; Nitric Oxide Synthase Type II; Pain; Prostatitis; Rats; Receptors, Neurokinin-1; Spinal Cord; Substance P

2009
Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis.
    Journal of dermatological science, 2010, Volume: 58, Issue:3

    Topics: Adrenergic Fibers; Adult; Aged; Aged, 80 and over; Biopsy; Chronic Disease; Dermatitis, Atopic; Dermis; Female; Fluorescent Antibody Technique; Humans; Male; Middle Aged; Prurigo; Pruritus; Sensory Receptor Cells; Substance P

2010
Plasma and saliva levels of nerve growth factor and neuropeptides in chronic migraine patients.
    Oral diseases, 2011, Volume: 17, Issue:2

    Topics: Adult; Calcitonin Gene-Related Peptide; Case-Control Studies; Chronic Disease; Facial Pain; Female; Humans; Male; Migraine Disorders; Nerve Growth Factor; Neuropeptides; Pain Measurement; Saliva; Salivary Proteins and Peptides; Secretory Rate; Sex Factors; Substance P

2011
Corticotropin-releasing factor, interleukin-6, brain-derived neurotrophic factor, insulin-like growth factor-1, and substance P in the cerebrospinal fluid of civilians with posttraumatic stress disorder before and after treatment with paroxetine.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:8

    Topics: Adult; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic Factor; Chronic Disease; Corticotropin-Releasing Hormone; Female; Humans; Insulin-Like Growth Factor I; Interleukin-6; Male; Middle Aged; Paroxetine; Personality Inventory; Psychometrics; Stress Disorders, Post-Traumatic; Substance P; Treatment Outcome

2011
Gender differences in reduced substance P (SP) in children with slow-transit constipation.
    Pediatric surgery international, 2011, Volume: 27, Issue:7

    Topics: Active Transport, Cell Nucleus; Adolescent; Biopsy; Child; Child, Preschool; Chronic Disease; Colon, Transverse; Constipation; Female; Follow-Up Studies; Gastrointestinal Transit; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Prevalence; Radionuclide Imaging; Retrospective Studies; Severity of Illness Index; Sex Distribution; Sex Factors; Substance P; Victoria

2011
Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux.
    Respirology (Carlton, Vic.), 2011, Volume: 16, Issue:4

    Topics: Adult; Aged; Asthma; Capsaicin; Chronic Disease; Cough; Cross-Sectional Studies; Female; Gastroesophageal Reflux; Histamine; Humans; Male; Middle Aged; Prospective Studies; Prostaglandin D2; Reflex; Respiratory Function Tests; Sputum; Substance P; Tryptases

2011
Substance P alterations in skin and brain of chronically stressed atopic-like mice.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2013, Volume: 27, Issue:2

    Topics: Animals; Base Sequence; Brain; Chronic Disease; Dermatitis, Atopic; DNA Primers; Female; Immunohistochemistry; Mice; Polymerase Chain Reaction; Skin; Stress, Physiological; Substance P

2013
Substance P and vasoactive intestinal peptide levels in middle ear effusions of children.
    Acta oto-laryngologica, 2012, Volume: 132, Issue:10

    Topics: Age Factors; Biomarkers; Child; Child, Preschool; Chronic Disease; Cohort Studies; Disease Progression; Female; Humans; Male; Otitis Media with Effusion; Prognosis; Prospective Studies; Recurrence; Sensitivity and Specificity; Severity of Illness Index; Sex Factors; Statistics, Nonparametric; Substance P; Vasoactive Intestinal Peptide

2012
Management of chronic pain in whiplash injury.
    The Journal of bone and joint surgery. British volume, 2002, Volume: 84, Issue:6

    Topics: Adult; Calcitonin Gene-Related Peptide; Chronic Disease; Decompression, Surgical; Diagnostic Techniques, Neurological; Female; Humans; Male; Median Nerve; Neck Pain; Prospective Studies; Shoulder Pain; Substance P; Trauma, Nervous System; Treatment Outcome; Whiplash Injuries

2002
[Chronic rhinosinusitis in hypogammaglobulinemia. A morphological study].
    HNO, 2002, Volume: 50, Issue:7

    Topics: Adult; Agammaglobulinemia; Calcitonin Gene-Related Peptide; Chronic Disease; Gene Expression; Genes, Recessive; Humans; Male; Microscopy, Immunoelectron; Nasal Mucosa; Rhinitis; Sex Chromosome Aberrations; Sinusitis; Substance P; Turbinates; X Chromosome

2002
Altered diurnal pattern of salivary substance P in adults with developmental disabilities and chronic self-injury.
    American journal of mental retardation : AJMR, 2003, Volume: 108, Issue:1

    Topics: Adult; Chronic Disease; Circadian Rhythm; Female; Humans; Hydrocortisone; Intellectual Disability; Male; Nociceptors; Saliva; Self-Injurious Behavior; Substance P

2003
[Repeated 100 Hz TENS for the treatment of chronic inflammatory pain in rats: optimal parameters and possible neuro-chemical mechanisms].
    Sheng li ke xue jin zhan [Progress in physiology], 1999, Volume: 30, Issue:1

    Topics: Animals; Arthralgia; Arthritis, Experimental; Chronic Disease; Dynorphins; Naltrexone; Pain Threshold; Rats; Substance P; Transcutaneous Electric Nerve Stimulation

1999
Nociception in persistent pancreatitis in rats: effects of morphine and neuropeptide alterations.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Amylases; Analgesics, Opioid; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Immunohistochemistry; Lipase; Male; Morphine; Neuropeptides; Organotin Compounds; Pain; Pain Measurement; Pancreas; Pancreatitis; Physical Stimulation; Rats; Rats, Inbred Lew; Substance P

2003
Changes in nasal mucosal innervation in horses with grass sickness.
    Equine veterinary journal, 2003, Volume: 35, Issue:1

    Topics: Acute Disease; Animals; Autonomic Nervous System Diseases; Biomarkers; Calcitonin Gene-Related Peptide; Chronic Disease; Horse Diseases; Horses; Immunohistochemistry; Intermediate Filament Proteins; Intermediate Filaments; Nasal Mucosa; Nerve Fibers; Rhinitis; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase

2003
Direct interstitial infusion of NK1-targeted neurotoxin into the spinal cord: a computational model.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:1

    Topics: Chronic Disease; Extracellular Space; Humans; Models, Biological; Neurotoxins; Pain; Receptors, Neurokinin-1; Spinal Cord; Substance P

2003
Chronic idiopathic slow transit constipation: pathophysiology and management.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2003, Volume: 5, Issue:4

    Topics: Autonomic Nervous System; Chronic Disease; Constipation; Gastrointestinal Transit; Humans; Neurosecretory Systems; Peptide YY; Substance P

2003
Substance P expression correlates with severity of diarrhea in cryptosporidiosis.
    The Journal of infectious diseases, 2003, Jul-15, Volume: 188, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; AIDS-Related Opportunistic Infections; Animals; Chronic Disease; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; Jejunum; Male; Middle Aged; RNA, Messenger; Substance P

2003
Molecular plasticity of primary nociceptive neurons: relations of the NGF-c-jun system to neurotomy and chronic pain.
    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 2003, Volume: 185, Issue:4

    Topics: Animals; Atrophy; Calcitonin Gene-Related Peptide; Chronic Disease; Female; Functional Laterality; Ganglia, Spinal; Male; Models, Neurological; Nerve Growth Factor; Neuronal Plasticity; Neurons; Nociceptors; Pain; Proto-Oncogene Proteins c-jun; Rats; Substance P; Vincristine

2003
Substance P regulates Th1-type colitis in IL-10 knockout mice.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Oct-01, Volume: 171, Issue:7

    Topics: Animals; Cells, Cultured; Chronic Disease; Colitis; Disease Models, Animal; Interleukin-10; Interleukin-12; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurokinin-1 Receptor Antagonists; Piroxicam; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Th1 Cells

2003
Hypothalamic response to experimental allergic encephalomyelitis: role of substance P.
    Neuroimmunomodulation, 2004, Volume: 11, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Body Weight; Chronic Disease; Corticosterone; Encephalomyelitis, Autoimmune, Experimental; Hypothalamus; Indoles; Isoindoles; Male; Mesencephalon; Neuroimmunomodulation; Neurokinin-1 Receptor Antagonists; Rats; Rats, Inbred Lew; Stress, Physiological; Substance P

2004
Elevated substance P levels in nasal lavage fluids from patients with chronic nonproductive cough and increased cough sensitivity to inhaled capsaicin.
    The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:4

    Topics: Administration, Inhalation; Adult; Capsaicin; Case-Control Studies; Cetirizine; Chronic Disease; Cough; Disease Susceptibility; Ephedrine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Nasal Decongestants; Nasal Lavage Fluid; Nasal Provocation Tests; Osmolar Concentration; Substance P

2003
[Expression and significance of substance P, neurofilament-H in glomus tumors with chronic pain].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2003, Volume: 41, Issue:12

    Topics: Adult; Aged; Chronic Disease; Female; Glomus Tumor; Humans; Immunohistochemistry; Male; Middle Aged; Neurofilament Proteins; Pain, Intractable; Substance P

2003
Substance P expression is elevated in inflamed human periradicular tissue.
    Journal of endodontics, 2004, Volume: 30, Issue:5

    Topics: Acute Disease; Chronic Disease; Humans; Neurogenic Inflammation; Neutrophils; Periapical Granuloma; Substance P

2004
Sustained potentiation by substance P of NMDA-activated current in rat primary sensory neurons.
    Brain research, 2004, Jun-04, Volume: 1010, Issue:1-2

    Topics: Animals; Benzylamines; Calcium Signaling; Cell Membrane; Cells, Cultured; Chelating Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Ganglia, Spinal; Membrane Potentials; Models, Biological; N-Methylaspartate; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Substance P; Sulfonamides

2004
Motor responses of rat hypertrophic intestine following chronic obstruction.
    Neurogastroenterology and motility, 2004, Volume: 16, Issue:3

    Topics: Acetylcholine; Animals; Chronic Disease; Electric Stimulation; Female; Gastrointestinal Motility; Hypertrophy; Intestinal Obstruction; Intestines; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Rats; Rats, Wistar; Substance P

2004
Stress-induced modulation of skin immune function: two types of antigen-presenting cells in the epidermis are differentially regulated by chronic stress.
    The British journal of dermatology, 2004, Volume: 151, Issue:1

    Topics: Animals; Antigen-Presenting Cells; Cadherins; Cell Differentiation; Cell Division; Chronic Disease; Corticosterone; Dermatitis, Contact; Immunization; Interleukin-1; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Models, Animal; Picryl Chloride; Skin; Social Isolation; Stress, Psychological; Substance P; Time Factors; Tumor Necrosis Factor-alpha

2004
[Research of the P substance on the olfactory mucous in sinusitis].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2004, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Humans; Male; Middle Aged; Olfactory Mucosa; Sinusitis; Substance P

2004
Morphological changes in the rat carotid body 1, 2, 4, and 8 weeks after the termination of chronically hypocapnic hypoxia.
    Histology and histopathology, 2004, Volume: 19, Issue:4

    Topics: Animals; Calcitonin Gene-Related Peptide; Carotid Body; Chronic Disease; Hypocapnia; Hypoxia; Immunohistochemistry; Nerve Fibers; Neuropeptide Y; Peptide Fragments; Rats; Rats, Wistar; Substance P; Time Factors; Vasoactive Intestinal Peptide

2004
Neuropeptide expression in rats exposed to chronic mild stresses.
    Psychopharmacology, 2005, Volume: 178, Issue:2-3

    Topics: Amygdala; Animals; Arcuate Nucleus of Hypothalamus; Brain; Brain Mapping; Chronic Disease; Dentate Gyrus; Depressive Disorder, Major; Disease Models, Animal; Galanin; Gene Expression Regulation; Hypothalamus; Male; Neuropeptide Y; Neuropeptides; Rats; Rats, Wistar; RNA, Messenger; Self Stimulation; Stress, Psychological; Substance P

2005
No evidence of increased serum substance P levels in chronic urticaria patients with and without demonstrable circulating vasoactive factors.
    Clinical and experimental dermatology, 2005, Volume: 30, Issue:2

    Topics: Adult; Basophil Degranulation Test; Biomarkers, Tumor; Chronic Disease; Humans; Hypersensitivity, Immediate; Skin Tests; Substance P; Tumor Protein, Translationally-Controlled 1; Urticaria

2005
Study of substance P, renin and aldosterone in chronic liver disease in Egyptian children.
    Journal of tropical pediatrics, 2005, Volume: 51, Issue:5

    Topics: Aldosterone; Case-Control Studies; Child; Chronic Disease; Egypt; Female; Humans; Liver Diseases; Male; Renin; Substance P

2005
Molecular and behavioral changes in nociception in a novel rat model of chronic pancreatitis for the study of pain.
    Pain, 2005, Volume: 117, Issue:1-2

    Topics: Amylases; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Gene Expression Regulation; Immunohistochemistry; Male; Nerve Growth Factor; Nociceptors; Pain; Pain Measurement; Pancreatitis; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Time Factors; Trinitrobenzenesulfonic Acid

2005
Spinal neuropeptide responses in persistent and transient pain following cervical nerve root injury.
    Spine, 2005, Nov-15, Volume: 30, Issue:22

    Topics: Acute Disease; Animals; Calcitonin Gene-Related Peptide; Cervical Vertebrae; Chronic Disease; Hyperalgesia; Immunohistochemistry; Male; Neck Pain; Neuralgia; Radiculopathy; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerve Roots; Substance P

2005
Morphological changes in the rat carotid body in acclimatization and deacclimatization to hypoxia.
    Advances in experimental medicine and biology, 2006, Volume: 580

    Topics: Acclimatization; Animals; Calcitonin Gene-Related Peptide; Carotid Body; Chronic Disease; Hypoxia; Neuropeptide Y; Rats; Substance P; Time Factors; Vasoactive Intestinal Peptide

2006
Effect of carbon dioxide on the structure of the carotid body: a comparison between normoxic and hypoxic conditions.
    Advances in experimental medicine and biology, 2006, Volume: 580

    Topics: Animals; Calcitonin Gene-Related Peptide; Carbon Dioxide; Carotid Body; Chronic Disease; Hypercapnia; Hypocapnia; Hypoxia; Neuropeptide Y; Rats; Substance P; Time Factors; Vasoactive Intestinal Peptide; Vasodilation

2006
Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides.
    American journal of physiology. Renal physiology, 2007, Volume: 292, Issue:1

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Bradykinin; Capsaicin; Chronic Disease; Colitis; Cystitis, Interstitial; Female; Mast Cells; Nerve Endings; Nerve Fibers, Unmyelinated; Neurons, Afferent; Neuropeptides; Pelvis; Physical Stimulation; Rats; Rats, Sprague-Dawley; Substance P; Trinitrobenzenesulfonic Acid; Urethane; Urinary Bladder

2007
Local and descending circuits regulate long-term potentiation and zif268 expression in spinal neurons.
    The European journal of neuroscience, 2006, Volume: 24, Issue:3

    Topics: Animals; Chronic Disease; Early Growth Response Protein 1; Efferent Pathways; Hot Temperature; Hyperalgesia; Long-Term Potentiation; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Nociceptors; Oligonucleotides, Antisense; Pain; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Substance P; Synaptic Transmission

2006
Substance P receptor mediated maintenance of chronic inflammation in EAE.
    Journal of neuroimmunology, 2006, Volume: 180, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; CD4-Positive T-Lymphocytes; Chronic Disease; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Female; Immunity, Cellular; Immunosuppression Therapy; Interferon-gamma; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neuroimmunomodulation; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Substance P

2006
Visceral pain perception is determined by the duration of colitis and associated neuropeptide expression in the mouse.
    Gut, 2007, Volume: 56, Issue:3

    Topics: Acute Disease; Animals; beta-Endorphin; CD4-Positive T-Lymphocytes; Chronic Disease; Colitis; Colon; Compliance; Interleukin-1beta; Male; Mice; Mice, Inbred BALB C; Neuropeptides; Pain; Pain Threshold; Physical Stimulation; Receptors, Opioid, mu; Substance P

2007
Deletion of mu- and kappa-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior.
    The Journal of investigative dermatology, 2007, Volume: 127, Issue:6

    Topics: Animals; Brain; CD4-Positive T-Lymphocytes; Chronic Disease; Dermatitis; Dermis; Epidermis; Female; Gene Expression; Homeostasis; Hypertrophy; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Endings; Pruritus; Receptors, Opioid, kappa; Receptors, Opioid, mu; RNA, Messenger; Substance P; Ubiquitin Thiolesterase

2007
Participation of capsaicin-sensitive afferent nerves in the gastric mucosa of patients with Helicobacter pylori-positive or-negative chronic gastritis.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:2

    Topics: Adult; Afferent Pathways; Aged; Breath Tests; Calcitonin Gene-Related Peptide; Capsaicin; Chronic Disease; Dyspepsia; Female; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Immunohistochemistry; Male; Middle Aged; Substance P; TRPV Cation Channels; Urea; Urease

2007
Study of substance P and its receptor neurokinin-1 in psoriasis and their relation to chronic stress and pruritus.
    Archives of dermatological research, 2007, Volume: 299, Issue:2

    Topics: Adult; Aged; Chronic Disease; Female; Gene Expression Regulation; Humans; Hydrocortisone; Male; Middle Aged; Pain Measurement; Pruritus; Psoriasis; Receptors, Neurokinin-1; Saliva; Skin; Stress, Psychological; Substance P

2007
[Activation of astrocytes effects changes of substance P in cornu dorsal medullae spinalis in chronic prostatitis rats].
    Zhonghua nan ke xue = National journal of andrology, 2007, Volume: 13, Issue:4

    Topics: Animals; Astrocytes; Chronic Disease; Male; Prostatitis; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2007
Nerve-related characteristics of ventral paratendinous tissue in chronic Achilles tendinosis.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2007, Volume: 15, Issue:10

    Topics: Achilles Tendon; Adult; Aged; Antibodies; Biopsy; Calcitonin Gene-Related Peptide; Chronic Disease; Female; Humans; Male; Middle Aged; Nerve Fibers; Receptors, Adrenergic, alpha-1; Receptors, Neurokinin-1; Substance P; Tendinopathy; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase

2007
Effects of the bisphosphonate ibandronate on hyperalgesia, substance P, and cytokine levels in a rat model of persistent inflammatory pain.
    European journal of pain (London, England), 2008, Volume: 12, Issue:3

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cytokines; Dinoprostone; Diphosphonates; Drug Evaluation, Preclinical; Edema; Foot; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Ibandronic Acid; Inflammation; Interleukin-1beta; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Tumor Necrosis Factor-alpha

2008
The differential effects of emotional or physical stress on pain behaviors or on c-Fos immunoreactivity in paraventricular nucleus or arcuate nucleus.
    Brain research, 2008, Jan-23, Volume: 1190

    Topics: Analysis of Variance; Animals; Arcuate Nucleus of Hypothalamus; Chronic Disease; Disease Models, Animal; Glutamic Acid; Immunohistochemistry; Injections, Spinal; Interferon-gamma; Interleukin-1beta; Male; Mice; Mice, Inbred ICR; Pain; Pain Threshold; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Statistics, Nonparametric; Stress, Psychological; Substance P; Tumor Necrosis Factor-alpha

2008
[Clinical significance of the functional and structural changes in the intestines in chronic cholecystitis].
    Klinicheskaia meditsina, 2007, Volume: 85, Issue:10

    Topics: Adult; Aged; Atrophy; Cholecystitis; Cholelithiasis; Chronic Disease; Colonic Polyps; Diagnosis, Differential; Erythrocyte Count; Erythrocytes; Female; Humans; Inflammation; Intestinal Mucosa; Male; Middle Aged; Motilin; Predictive Value of Tests; Prognosis; Substance P

2007
Association of insertion/deletion polymorphism of the angiotensin-converting enzyme gene with angio-oedema accompanying chronic urticaria but not chronic urticaria without angio-oedema or the autologous serum skin test response.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2008, Volume: 22, Issue:1

    Topics: Adult; Alleles; Angioedema; Case-Control Studies; Chronic Disease; Disease Susceptibility; Female; Genotype; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Substance P; Urticaria

2008
[Effect of electroacupuncture of local plus distal acupoints in the same segments of spinal cord on spinal substance P expression in rats with chronic radicular pain].
    Zhen ci yan jiu = Acupuncture research, 2008, Volume: 33, Issue:1

    Topics: Acupuncture Points; Animals; Chronic Disease; Electroacupuncture; Motor Activity; Pain Management; Pain Threshold; Random Allocation; Rats; Rats, Wistar; Spinal Cord; Substance P

2008
Neural and hormonal peptides in rectal biopsy specimens from patients with Chagas' disease and chronic autonomic failure.
    Lancet (London, England), 1980, Mar-15, Volume: 1, Issue:8168 Pt 1

    Topics: Autonomic Nervous System; Biopsy; Chagas Disease; Chronic Disease; Gastrointestinal Hormones; Humans; Intestinal Diseases, Parasitic; Nervous System Diseases; Rectum; Somatostatin; Substance P; Vasoactive Intestinal Peptide

1980
[Substance P and pain: possible pathogenic role in chronic primary headache].
    La Clinica terapeutica, 1980, Dec-15, Volume: 95, Issue:5

    Topics: Chronic Disease; Headache; Humans; Pain; Substance P

1980
Endogenous substance P inhibits the expression of corticotropin-releasing hormone during a chronic inflammatory stress.
    Life sciences, 1995, Volume: 57, Issue:22

    Topics: Adrenocorticotropic Hormone; Animals; Arthritis, Experimental; Chronic Disease; Corticotropin-Releasing Hormone; Hypothalamus; Inflammation; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Physiological; Substance P

1995
Innervation of recurrent aphthous ulcers.
    Oral microbiology and immunology, 1994, Volume: 9, Issue:1

    Topics: Adult; Calcitonin Gene-Related Peptide; Chronic Disease; Female; Humans; Male; Middle Aged; Mouth Mucosa; Pain; Recurrence; Stomatitis, Aphthous; Substance P

1994
Differential effects of experimentally induced chronic pancreatitis on neuropeptide immunoreactivities in the feline pancreas.
    Pancreas, 1993, Volume: 8, Issue:6

    Topics: Animals; Calcitonin Gene-Related Peptide; Cats; Chronic Disease; Constriction; Female; Gastrin-Releasing Peptide; Immunohistochemistry; Male; Neuropeptide Y; Neuropeptides; Pancreas; Pancreatic Ducts; Pancreatitis; Peptides; Substance P; Tachykinins; Vasoactive Intestinal Peptide

1993
[Met-enkephalin and substance P. Comparison of CSF levels in patients with chronic pain based on a sampling procedure].
    Revue neurologique, 1993, Volume: 149, Issue:6-7

    Topics: Adult; Aged; Chronic Disease; Enkephalin, Methionine; Female; Humans; Male; Middle Aged; Pain; Sampling Studies; Spinal Puncture; Substance P; Ventriculoperitoneal Shunt

1993
Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:2

    Topics: Animals; Arginine; Chronic Disease; Hypertension; Hypoxia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Substance P; Vasoconstriction

1994
Prevaccination with diluted Freund adjuvant prevents the development of chronic pain and transient release of cerebrospinal fluid substance P in adjuvant-induced arthritis in rats.
    Pain, 1994, Volume: 58, Issue:2

    Topics: Animals; Arthritis, Experimental; Behavior, Animal; Body Weight; Chronic Disease; Freund's Adjuvant; Hindlimb; Motor Activity; Pain; Pain Measurement; Rats; Substance P; Vaccination; Vocalization, Animal

1994
Elevated substance P content in induced sputum from patients with asthma and patients with chronic bronchitis.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:3 Pt 1

    Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchitis; Chronic Disease; Eosinophils; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Radioimmunoassay; Saline Solution, Hypertonic; Sputum; Substance P; Vital Capacity

1995
Capsaicin pretreatment attenuates chronic hypoxic pulmonary hypertension.
    Respiration physiology, 1995, Volume: 99, Issue:2

    Topics: Animals; Blood Pressure; Capsaicin; Chronic Disease; Female; Hypertension, Pulmonary; Hypoxia; Neprilysin; Pulmonary Circulation; Random Allocation; Rats; Rats, Wistar; Substance P; Tachykinins

1995
Changes in neuroendocrine elements in bronchial mucosa in chronic lung disease in adults.
    Thorax, 1995, Volume: 50, Issue:5

    Topics: Adult; Aged; Bronchi; Calcitonin; Calcitonin Gene-Related Peptide; Chromogranin A; Chromogranins; Chronic Disease; Gastrin-Releasing Peptide; Gastrins; Humans; Immunohistochemistry; Lung Diseases; Middle Aged; Mucous Membrane; Neurosecretory Systems; Peptides; Serotonin; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase

1995
Neuropeptide changes in compressed spinal nerve roots.
    Spine, 1995, Mar-15, Volume: 20, Issue:6

    Topics: Animals; Chronic Disease; Disease Models, Animal; Female; Ganglia, Spinal; Male; Nerve Compression Syndromes; Spinal Nerve Roots; Substance P; Swine; Vasoactive Intestinal Peptide

1995
Effects of chronic hypoxia on the secretory responses of rat salivary glands.
    Archives of oral biology, 1995, Volume: 40, Issue:5

    Topics: Animals; Barotrauma; Chronic Disease; Female; Hypoxia; Isoproterenol; Methacholine Chloride; Methoxamine; Parotid Gland; Rats; Rats, Wistar; Saliva; Salivary Glands; Secretory Rate; Stimulation, Chemical; Submandibular Gland; Substance P; Xerostomia

1995
An immunocytochemical study on relations between mast cell and peptidergic terminals in nasal mucosa of chronic rhinitis patients.
    Chinese medical journal, 1995, Volume: 108, Issue:8

    Topics: Adult; Chronic Disease; Female; Humans; Immunohistochemistry; Male; Mast Cells; Nasal Mucosa; Nerve Endings; Rhinitis; Substance P

1995
Substance P levels in the rectal mucosa of diabetic patients with normal bowel function and constipation.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:1

    Topics: Adult; Chronic Disease; Constipation; Diabetes Complications; Diabetes Mellitus; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Radioimmunoassay; Rectum; Substance P

1993
Substance P-like immunoreactivity and analgesic effects of vibratory stimulation on patients suffering from chronic pain.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1993, Volume: 20, Issue:2

    Topics: Adult; Aged; Analgesia; Chronic Disease; Female; Humans; Male; Middle Aged; Pain; Pain Management; Pain Measurement; Physical Stimulation; Radioimmunoassay; Substance P; Vibration

1993
Immunoreactive substance P in human saliva. A possible marker of chronic pain.
    Annals of the New York Academy of Sciences, 1993, Sep-20, Volume: 694

    Topics: Adult; Biomarkers; Blood Proteins; Chronic Disease; Humans; Low Back Pain; Middle Aged; Saliva; Salivary Proteins and Peptides; Substance P

1993
Evidence for altered control of hypothalamic CRF in immune-mediated diseases.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 771

    Topics: Acute Disease; Animals; Arginine Vasopressin; Arthritis, Experimental; Chronic Disease; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Hypothalamus; Inflammation; Mice; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Stress, Physiological; Substance P

1995
Substance P content and preprotachykinin gene-I mRNA expression in a rat model of chronic bronchitis.
    American journal of respiratory cell and molecular biology, 1996, Volume: 14, Issue:4

    Topics: Animals; Base Sequence; Bronchitis; Chronic Disease; Disease Models, Animal; Ganglia, Spinal; Gene Expression; Lung; Molecular Sequence Data; Nodose Ganglion; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Sulfur Dioxide; Tachykinins; Trachea

1996
Chromic gut suture reduces calcitonin-gene-related peptide and substance P levels in the spinal cord following chronic constriction injury in the rat.
    Pain, 1996, Volume: 64, Issue:3

    Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Chromium Compounds; Chronic Disease; Constriction, Pathologic; Male; Nerve Tissue Proteins; Pain; Peripheral Nerve Injuries; Peripheral Nerves; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Substance P; Sutures

1996
Pre- and postnatal effects of chronic maternal hypoxia on substance-P immunoreactivity in rabbit brainstem regions.
    Developmental neuroscience, 1995, Volume: 17, Issue:5-6

    Topics: Animals; Brain Stem; Chronic Disease; Female; Hypoxia; Immunohistochemistry; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Substance P

1995
Intestinal neuronal dysplasia. Defining a new cause for chronic constipation.
    Australian family physician, 1996, Volume: 25, Issue:9

    Topics: Chronic Disease; Constipation; Gastrointestinal Motility; Humans; Self-Help Groups; Substance P

1996
Chronic parasite infection in mice induces brain granulomas and differentially alters brain nerve growth factor levels and thermal responses in paws.
    Acta neuropathologica, 1996, Volume: 92, Issue:3

    Topics: Animals; Brain; Burns; Chronic Disease; Extremities; Female; Granuloma; Mice; Mice, Inbred Strains; Nerve Growth Factors; Physical Stimulation; Schistosoma mansoni; Schistosomiasis mansoni; Substance P

1996
Alteration in central and peripheral substance P- and neuropeptide Y-like immunoreactivity after chronic hypoxia in the rat.
    Brain research, 1996, Sep-09, Volume: 733, Issue:1

    Topics: Adrenal Glands; Animals; Antibodies; Brain Chemistry; Carotid Body; Chronic Disease; Ganglia, Sympathetic; Hypoxia; Male; Neuropeptide Y; Pituitary Gland, Anterior; Proteins; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P

1996
Chronic placental insufficiency in the fetal guinea pig affects neurochemical and neuroglial development but not neuronal numbers in the brainstem: a new method for combined stereology and immunohistochemistry.
    The Journal of comparative neurology, 1997, Mar-03, Volume: 379, Issue:1

    Topics: Animals; Brain Chemistry; Brain Stem; Cell Count; Chronic Disease; Enkephalin, Methionine; Female; Fetal Growth Retardation; Glial Fibrillary Acidic Protein; Guinea Pigs; Hypoglossal Nerve; Immunohistochemistry; Neuroglia; Placental Insufficiency; Pregnancy; Substance P

1997
Distribution of substance P and calcitonin gene-related peptide immunoreactive nerve fibers in the trachea of chronically hypoxic rats.
    Brain research bulletin, 1996, Volume: 39, Issue:6

    Topics: Animals; Calcitonin Gene-Related Peptide; Chronic Disease; Hypoxia; Immunohistochemistry; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Reference Values; Substance P; Trachea

1996
Effect of chronic myocardial infarction on in vivo reactivity of skeletal muscle arterioles.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 2

    Topics: Acetylcholine; Animals; Arginine; Arterioles; Calcitonin Gene-Related Peptide; Chronic Disease; Hemodynamics; Male; Muscle, Skeletal; Myocardial Infarction; Nitroprusside; Rats; Rats, Sprague-Dawley; Substance P; Vasomotor System

1997
Deficiency of substance P-immunoreactive nerve fibres in children with intractable constipation: a form of intestinal neuronal dysplasia.
    Journal of paediatrics and child health, 1997, Volume: 33, Issue:3

    Topics: Biopsy; Child; Chronic Disease; Colon; Constipation; Gastrointestinal Motility; Humans; Nerve Fibers; Substance P

1997
Renal function of substance P in rats chronically exposed to hypoxia.
    Aviation, space, and environmental medicine, 1997, Volume: 68, Issue:8

    Topics: Altitude Sickness; Animals; Chronic Disease; Disease Models, Animal; Female; Glomerular Filtration Rate; Hypoxia; Infusions, Intravenous; Kallikreins; Kidney; Rats; Rats, Wistar; Sodium; Substance P

1997
Effects of experimental Mycoplasma pulmonis infection on sensory neuropeptides and airway mucosa in the rat.
    The European respiratory journal, 1997, Volume: 10, Issue:10

    Topics: Animals; Blotting, Northern; Calcitonin Gene-Related Peptide; Chronic Disease; Culture Techniques; Disease Models, Animal; Immunohistochemistry; Male; Mucous Membrane; Mycoplasma Infections; Nasal Mucosa; Neuropeptides; Rats; Rats, Inbred Strains; Respiratory Tract Infections; Substance P; Trachea; Trigeminal Ganglion

1997
Increased VIP-positive nerve fibers in the mucous glands of subjects with chronic bronchitis.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bronchi; Bronchitis; Calcitonin Gene-Related Peptide; Chronic Disease; Exocrine Glands; Humans; Immunohistochemistry; Male; Middle Aged; Mucus; Nerve Tissue Proteins; Neurons; Smoking; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide

1997
Temporal changes in spinal cord expression of mRNA for substance P, dynorphin and enkephalin in a model of chronic pain.
    Acta physiologica Scandinavica, 1997, Volume: 161, Issue:4

    Topics: Animals; Behavior, Animal; Chronic Disease; Disease Models, Animal; Dynorphins; Enkephalins; Gene Expression; Male; Neuropeptides; Pain; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Substance P; Time Factors

1997
Innervation of nasal turbinate blood vessels in rhinitic and nonrhinitic children.
    American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:6 Pt 1

    Topics: Arteries; Arteriovenous Anastomosis; Blood Vessels; Calcitonin Gene-Related Peptide; Child; Child, Preschool; Chronic Disease; Humans; Immunohistochemistry; Nasal Mucosa; Nerve Fibers; Nerve Tissue Proteins; Neuropeptide Y; Peptide Fragments; Rhinitis; Substance P; Thiolester Hydrolases; Turbinates; Ubiquitin Thiolesterase

1998
Attenuation of isocapnic hyperpnoea-induced guinea-pig bronchoconstriction by chronic hypoxia.
    The European respiratory journal, 1998, Volume: 11, Issue:5

    Topics: Animals; Bronchial Spasm; Capsaicin; Carbon Dioxide; Chronic Disease; Forced Expiratory Volume; Guinea Pigs; Hypoxia; Lung; Male; Neprilysin; Pulmonary Ventilation; Respiration; Substance P; Trachea

1998
Pain treatment of fibromyalgia by acupuncture.
    Rheumatology international, 1998, Volume: 18, Issue:1

    Topics: Acupuncture Therapy; Biomarkers; Blood Platelets; Chronic Disease; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Pain Management; Pain Measurement; Platelet Count; Serotonin; Substance P; Treatment Outcome

1998
Calcitonin gene-related peptide mediates the protective effect of sensory nerves in a model of colonic injury.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Calcitonin Gene-Related Peptide; Chronic Disease; Colitis, Ulcerative; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Protein Biosynthesis; Rats; Rats, Wistar; Substance P

1998
Bronchial mucosal immunoreactivity of sensory neuropeptides in severe airway diseases.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Asthma; Beclomethasone; Biomarkers; Biopsy; Bronchi; Bronchitis; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capillary Permeability; Chronic Disease; Epithelium; Female; Fluorescent Antibody Technique, Direct; Glucocorticoids; Humans; Male; Middle Aged; Mucous Membrane; Muscle, Smooth; Nerve Tissue Proteins; Neuropeptide Y; Neuropeptides; Prednisone; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide; Vasomotor System

1998
[A study on the cumulative effect of repeated electroacupuncture on chronic pain].
    Sheng li ke xue jin zhan [Progress in physiology], 1996, Volume: 27, Issue:3

    Topics: Acupuncture Analgesia; Animals; Arthritis, Experimental; Chronic Disease; Electroacupuncture; Humans; Pain Management; Rats; Sincalide; Substance P

1996
Angiogenesis in mice with chronic airway inflammation: strain-dependent differences.
    The American journal of pathology, 1998, Volume: 153, Issue:4

    Topics: Animals; Capillary Permeability; Cell Count; Chronic Disease; Endothelium, Vascular; Evans Blue; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neovascularization, Pathologic; Pneumonia, Mycoplasma; Silver Staining; Species Specificity; Specific Pathogen-Free Organisms; Substance P; Trachea; Tracheitis; Wheat Germ Agglutinins

1998
Antioxidants attenuate chronic hypoxic pulmonary hypertension.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:5

    Topics: Animals; Antioxidants; Body Weight; Chronic Disease; Free Radicals; Hypertension, Pulmonary; Hypoxia; Male; Rats; Rats, Wistar; Substance P; Thiourea

1998
Relationship between neuronal activity and substance P-immunoreactivity in the rat spinal cord during acute and persistent myositis.
    Neuroscience letters, 1998, Nov-20, Volume: 257, Issue:1

    Topics: Acute Disease; Animals; Carrageenan; Chronic Disease; Electric Stimulation; Freund's Adjuvant; Male; Myositis; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Time Factors

1998
Cholinergic stimulation and nonadrenergic, noncholinergic relaxation of human colonic circular muscle in idiopathic chronic constipation.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:12

    Topics: Acetylcholine; Adenosine Triphosphate; Adult; Atropine; Cholinergic Fibers; Chronic Disease; Colon; Constipation; Electric Stimulation; Gastrointestinal Motility; Guanethidine; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Substance P; Vasoactive Intestinal Peptide

1998
Free radicals contribute to the reduction in peripheral vascular responses and the maintenance of thermal hyperalgesia in rats with chronic constriction injury.
    Pain, 1999, Volume: 79, Issue:1

    Topics: Animals; Antioxidants; Behavior, Animal; Chronic Disease; Constriction, Pathologic; Free Radicals; Hyperalgesia; Male; Peripheral Nerve Injuries; Pregnatrienes; Rats; Rats, Sprague-Dawley; Skin; Substance P; Superoxide Dismutase; Temperature; Vasodilation

1999
Actions of intrathecal diphtheria toxin-substance P fusion protein on models of persistent pain.
    Pain, 1999, Volume: 79, Issue:2-3

    Topics: Acute Disease; Animals; Carrageenan; Chronic Disease; Constriction, Pathologic; Diphtheria Toxin; Hyperalgesia; Immunohistochemistry; Inflammation; Injections, Spinal; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Sciatic Nerve; Substance P

1999
Chronic pain is associated with increased TrkA immunoreactivity in spinoreticular neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jul-01, Volume: 19, Issue:13

    Topics: Afferent Pathways; Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Cell Count; Cell Size; Chronic Disease; Immunohistochemistry; Lumbosacral Region; Male; Nerve Growth Factors; Neuronal Plasticity; Neurons; Pain; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Spinal Cord; Substance P

1999
Rat model of Achilles tendon disorder. A pilot study.
    Cells, tissues, organs, 1999, Volume: 165, Issue:1

    Topics: Achilles Tendon; Animals; Biomechanical Phenomena; Calcitonin Gene-Related Peptide; Chronic Disease; Collagen; Cumulative Trauma Disorders; Disease Models, Animal; Gait; Hindlimb; Hip Joint; Male; Peripheral Nerves; Physical Conditioning, Animal; Pilot Projects; Rats; Rats, Sprague-Dawley; Substance P; Torque

1999
Vasoactive-intestinal-peptide- and substance-P-immunoreactive nerve fibres in the myenteric plexus of mouse colon during the chronic phase of Trypanosoma cruzi infection.
    Annals of tropical medicine and parasitology, 1999, Volume: 93, Issue:1

    Topics: Animals; Chagas Disease; Chronic Disease; Colon; Immunohistochemistry; Male; Mice; Microscopy, Electron; Myenteric Plexus; Neurons; Substance P; Vacuoles; Vasoactive Intestinal Peptide

1999
Loss of nerve: a molecular approach to better treatment of chronic pain.
    JAMA, 2000, Jan-12, Volume: 283, Issue:2

    Topics: Animals; Chronic Disease; Humans; Immunotoxins; N-Glycosyl Hydrolases; Neurosurgical Procedures; Pain, Intractable; Plant Proteins; Ribosome Inactivating Proteins, Type 1; Ricin; Saporins; Sensory Receptor Cells; Substance P

2000
Changes in the peptidergic innervation of the rat carotid body a month after the termination of chronic hypoxia.
    Advances in experimental medicine and biology, 2000, Volume: 475

    Topics: Animals; Calcitonin Gene-Related Peptide; Carotid Body; Chronic Disease; Hypoxia; Immunohistochemistry; Neuropeptide Y; Neuropeptides; Rats; Substance P; Time Factors; Vasoactive Intestinal Peptide

2000
Expression of interleukin 8 (IL-8) and substance P in human chronic pancreatitis.
    Gut, 2000, Volume: 47, Issue:3

    Topics: Adult; Blotting, Northern; Case-Control Studies; Chronic Disease; Female; Gene Expression; Humans; Interleukin-8; Male; Middle Aged; Pancreas; Pancreatic Ducts; Pancreatitis; Protein Precursors; RNA, Messenger; Substance P; Tachykinins

2000
Disorder-specific changes in innervation in oral lichen planus and lichenoid reactions.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2000, Volume: 29, Issue:8

    Topics: Adult; Aged; Analysis of Variance; Basement Membrane; Calcitonin Gene-Related Peptide; Chronic Disease; Humans; Lichen Planus, Oral; Lichenoid Eruptions; Middle Aged; Mouth Diseases; Mouth Mucosa; Nerve Fibers; Nerve Tissue Proteins; Neuropeptide Y; Statistics, Nonparametric; Stomatitis; Substance P; Sympathetic Nervous System; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide

2000
The loss of sympathetic nerve fibers in the synovial tissue of patients with rheumatoid arthritis is accompanied by increased norepinephrine release from synovial macrophages.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:13

    Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Chronic Disease; Cytokines; Electric Stimulation; Humans; Knee Joint; Macrophages; Middle Aged; Nerve Fibers; Norepinephrine; Osteoarthritis; Sensory Receptor Cells; Substance P; Sympathetic Nervous System; Synovial Membrane

2000
Characterization of itch-associated responses of NC mice with mite-induced chronic dermatitis.
    Journal of dermatological science, 2001, Volume: 25, Issue:1

    Topics: Animals; Attention; Chronic Disease; Dermatitis; Female; Histamine; Immunoglobulin E; Mice; Mice, Inbred Strains; Mites; Naltrexone; Narcotic Antagonists; Pruritus; Serotonin; Substance P

2001
Airway vasculature after mycoplasma infection: chronic leakiness and selective hypersensitivity to substance P.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 280, Issue:2

    Topics: Albuterol; Animals; Bronchodilator Agents; Capillary Permeability; Chronic Disease; Dose-Response Relationship, Drug; Drug Hypersensitivity; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Indoles; Male; Mycoplasma Infections; Organ Size; Organometallic Compounds; Platelet Activating Factor; Rats; Rats, Inbred F344; Rats, Wistar; Salmeterol Xinafoate; Serotonin; Species Specificity; Specific Pathogen-Free Organisms; Substance P; Trachea

2001
[No relation between angiotensin-converting enzyme (ACE) inhibitor-induced cough and ACE gene polymorphism, plasma bradykinin, substance P and ACE inhibitor concentration in Japanese patients].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:3

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Chronic Disease; Cough; Female; Humans; Hypertension; Indoles; Male; Middle Aged; Nephritis; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Substance P

2001
Influence of painful chronic neuropathy on neurogenic inflammation.
    Pain, 2001, Volume: 92, Issue:1-2

    Topics: Administration, Topical; Analgesics; Animals; Capsaicin; Chronic Disease; Coloring Agents; Electric Stimulation; Evans Blue; Hot Temperature; Indoles; Isoindoles; Ligation; Male; Nerve Fibers; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sciatic Nerve; Sciatica; Substance P

2001
Substance P in rectal mucosa of children with chronic constipation.
    Acta gastroenterologica Latinoamericana, 2001, Volume: 31, Issue:1

    Topics: Case-Control Studies; Child; Child, Preschool; Chronic Disease; Constipation; Female; Follow-Up Studies; Humans; Infant; Intestinal Mucosa; Male; Radioimmunoassay; Substance P

2001
Differential alterations in tachykinin NK2 receptors in isolated colonic circular smooth muscle in inflammatory bowel disease and idiopathic chronic constipation.
    Regulatory peptides, 2001, Jun-15, Volume: 99, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Carbachol; Cholinergic Agonists; Chronic Disease; Colon; Constipation; Female; Humans; Inflammatory Bowel Diseases; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P

2001
Levels of nerve growth factor in cerebrospinal fluid of chronic daily headache patients.
    Neurology, 2001, Jul-10, Volume: 57, Issue:1

    Topics: Adult; Calcitonin Gene-Related Peptide; Chronic Disease; Circadian Rhythm; Female; Headache; Humans; Male; Middle Aged; Nerve Growth Factor; Reference Values; Substance P

2001
Presence and distribution of sensory nerve fibers in human peritoneal adhesions.
    Annals of surgery, 2001, Volume: 234, Issue:2

    Topics: Calcitonin Gene-Related Peptide; Chronic Disease; Humans; Laparoscopy; Microscopy, Electron; Nerve Fibers; Nociceptors; Pelvic Pain; Peritoneum; Substance P; Tissue Adhesions

2001
Decreases in endomorphin-2-like immunoreactivity concomitant with chronic pain after nerve injury.
    Neuroscience, 2001, Volume: 105, Issue:3

    Topics: Animals; Calcitonin Gene-Related Peptide; Chronic Disease; Down-Regulation; Functional Laterality; Hyperalgesia; Immunohistochemistry; Ligation; Male; Mice; Mice, Inbred ICR; Nerve Crush; Neuralgia; Oligopeptides; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Posterior Horn Cells; Reaction Time; Sciatic Nerve; Substance P

2001
Spontaneous chronic corneal epithelial defects (SCCED) in dogs: clinical features, innervation, and effect of topical SP, with or without IGF-1.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:10

    Topics: Administration, Topical; Animals; Calcitonin Gene-Related Peptide; Chronic Disease; Corneal Diseases; Dog Diseases; Dogs; Drug Therapy, Combination; Epithelium, Corneal; Female; Fluorophotometry; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Substance P; Thiolester Hydrolases; Trigeminal Nerve; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide

2001
An investigation of immunocompetence substances in normal gingival and periodontitis tissue.
    Chinese medical journal, 2000, Volume: 113, Issue:9

    Topics: Adult; Calcitonin Gene-Related Peptide; Chronic Disease; Endothelins; Female; Gingiva; Humans; Immunohistochemistry; Male; Nitric Oxide; Periodontitis; Protein Biosynthesis; Substance P

2000
Temporal increase in the reactivity of pulmonary vasculature to substance P in chronically hypoxic rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:3

    Topics: Altitude; Animals; Blood Pressure; Blood Vessels; Capillaries; Chronic Disease; Female; Hypoxia; In Vitro Techniques; Piperidines; Pulmonary Circulation; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; RNA, Messenger; Substance P; Time Factors

2002
Loss of dipeptidylpeptidase IV activity in chronic rhinosinusitis contributes to the neurogenic inflammation induced by substance P in the nasal mucosa.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:9

    Topics: Animals; Chronic Disease; Dipeptidyl Peptidase 4; Humans; Models, Biological; Nasal Mucosa; Rhinitis; Substance P; Swine; Vascular Resistance; Vasodilator Agents

2002
Temporal decrease in renal sensory responses in rats after chronic ligation of the bile duct.
    American journal of physiology. Renal physiology, 2002, Volume: 283, Issue:1

    Topics: Animals; Cholestasis; Chronic Disease; Disease Models, Animal; Gene Expression; Kidney; Ligation; Liver Cirrhosis, Biliary; Male; Neurons, Afferent; Physical Stimulation; Rats; Rats, Wistar; Receptors, Neurokinin-1; Reflex; RNA, Messenger; Sodium Chloride; Substance P; Urinary Catheterization; Urine

2002
Autoradiographic analysis of 125I-substance P binding in rat spinal cord following chronic constriction injury of the sciatic nerve.
    Brain research, 1992, Nov-20, Volume: 596, Issue:1-2

    Topics: Animals; Autoradiography; Chronic Disease; Constriction, Pathologic; Defense Mechanisms; Indicators and Reagents; Iodine Radioisotopes; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Nerve; Spinal Cord; Substance P; Succinimides; Wounds, Nonpenetrating

1992
Vasoactive intestinal polypeptide and substance P in the pathogenesis of atopic dermatitis.
    Acta dermato-venereologica. Supplementum, 1992, Volume: 176

    Topics: Adolescent; Adult; Child; Chronic Disease; Dermatitis, Atopic; Female; Humans; Male; Peptide Fragments; Radioimmunoassay; Skin; Substance P; Vasoactive Intestinal Peptide

1992
Changes in peptidergic innervation in chronic pancreatitis.
    Pancreas, 1992, Volume: 7, Issue:2

    Topics: Adult; Calcitonin Gene-Related Peptide; Chronic Disease; Female; Humans; Male; Nerve Fibers; Neuropeptide Y; Neuropeptides; Pain; Pancreas; Pancreatitis; Peptide PHI; Substance P; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide

1992
Decreased neuropeptide-converting enzyme activities in cerebrospinal fluid during acute but not chronic phases of collagen induced arthritis in rats.
    Brain research, 1992, May-29, Volume: 581, Issue:2

    Topics: Acute Disease; Amino Acid Sequence; Analysis of Variance; Animals; Arthritis, Experimental; Chromatography, High Pressure Liquid; Chronic Disease; Collagen; Cysteine Endopeptidases; Dynorphins; Hemoglobins; Metalloendopeptidases; Molecular Sequence Data; Rats; Rats, Wistar; Regression Analysis; Substance P; Time Factors

1992
The role of substance P and calcitonin gene-related peptide containing nerve fibers in maintaining fungiform taste buds in the rat after a chronic chorda tympani nerve injury.
    Experimental neurology, 1991, Volume: 113, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Chorda Tympani Nerve; Chronic Disease; Female; Immunohistochemistry; Nerve Fibers; Rats; Rats, Inbred Strains; Substance P; Taste Buds

1991
[The effect of substance P on the individual and group behaviors of rhesus monkeys].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1991, Issue:3

    Topics: Animals; Behavior, Animal; Blood Pressure; Chronic Disease; Group Processes; Hierarchy, Social; Hypertension; Macaca mulatta; Male; Restraint, Physical; Stress, Psychological; Substance P

1991
[A preliminary study on substance P and vasoactive intestinal polypeptide contents in intestinal mucosa of chronic diarrhea with splenic weakness].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991, Volume: 11, Issue:3

    Topics: Adult; Chronic Disease; Diarrhea; Female; Humans; Intestinal Mucosa; Male; Splenic Diseases; Substance P; Vasoactive Intestinal Peptide

1991
Neurones with epileptiform discharge in the central nervous system and chronic pain. Experimental and clinical investigations.
    Acta neurochirurgica. Supplementum, 1991, Volume: 52

    Topics: Animals; Chronic Disease; Cortical Spreading Depression; Electroencephalography; Epilepsy; Evoked Potentials; Humans; Locus Coeruleus; Neurons; Pain; Raphe Nuclei; Rats; Somatosensory Cortex; Substance P; Thalamic Nuclei

1991
Substance P in chronic pain.
    Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1991, Volume: 62, Issue:3-4

    Topics: Adrenocorticotropic Hormone; Back Pain; beta-Endorphin; Chronic Disease; Electric Stimulation Therapy; Electrodes, Implanted; Humans; Pain; Spinal Cord; Substance P; Time Factors

1991
Long-term high frequency transcutaneous electrical nerve stimulation (hi-TNS) in chronic pain. Clinical response and effects on CSF-endorphins, monoamine metabolites, substance P-like immunoreactivity (SPLI) and pain measures.
    Journal of psychosomatic research, 1985, Volume: 29, Issue:3

    Topics: Adult; Aged; Chronic Disease; Electric Stimulation Therapy; Endorphins; Female; Follow-Up Studies; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Pain; Pain Management; Phenylacetates; Radioimmunoassay; Substance P; Transcutaneous Electric Nerve Stimulation

1985
Possible neurohumoral mechanisms in CNS stimulation for pain suppression.
    Applied neurophysiology, 1985, Volume: 48, Issue:1-6

    Topics: Brain; Chronic Disease; Electric Stimulation Therapy; Electrodes, Implanted; Ganglia, Spinal; Humans; Neurotransmitter Agents; Pain; Pain Management; Periaqueductal Gray; Spinal Cord; Substance P

1985
Idiopathic chronic constipation is associated with decreased colonic vasoactive intestinal peptide.
    Gastroenterology, 1988, Volume: 94, Issue:2

    Topics: Adult; Bombesin; Chronic Disease; Colon; Constipation; Enkephalin, Methionine; Female; Humans; Immunohistochemistry; Intestinal Mucosa; Male; Middle Aged; Muscle, Smooth; Peptide PHI; Radioimmunoassay; Substance P; Vasoactive Intestinal Peptide

1988
Spinal cord neuropeptides in a case of chronic pain.
    Lancet (London, England), 1988, May-07, Volume: 1, Issue:8593

    Topics: Calcitonin Gene-Related Peptide; Chronic Disease; Humans; Immunohistochemistry; Male; Middle Aged; Neuropeptides; Pain; Spinal Cord; Substance P

1988
Substance P in CSF of patients with chronic pain syndromes.
    Pain, 1988, Volume: 33, Issue:1

    Topics: Adult; Aged; Chronic Disease; Depression; Female; Humans; Male; Middle Aged; Nervous System Diseases; Pain; Pain, Intractable; Personality Inventory; Substance P; Syndrome

1988
[Changes in the hormone content of the blood during chronic electrical stimulation of the midbrain].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1988, Volume: 74, Issue:7

    Topics: Animals; Chronic Disease; Electric Stimulation; Hormones; Mesencephalon; Rabbits; Stress, Psychological; Substance P; Time Factors

1988
Chronic pancreatitis and diabetes mellitus: plasma and gastroduodenal mucosal profiles of regulatory peptides (gastrin, motilin, secretin, cholecystokinin, gastric inhibitory polypeptide, somatostatin, VIP, substance P, pancreatic polypeptide, glucagon, e
    Hepato-gastroenterology, 1988, Volume: 35, Issue:5

    Topics: Adult; Chronic Disease; Diabetes Mellitus; Female; Gastric Inhibitory Polypeptide; Gastric Mucosa; Gastrins; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Male; Middle Aged; Motilin; Neurotensin; Pancreatic Polypeptide; Pancreatitis; Secretin; Somatostatin; Substance P; Vasoactive Intestinal Peptide

1988
Colonic substance P levels are increased in ulcerative colitis and decreased in chronic severe constipation.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:5

    Topics: Biopsy; Chronic Disease; Colitis, Ulcerative; Colon; Constipation; Gastrointestinal Transit; Hemorrhoids; Humans; Intestinal Mucosa; Radioimmunoassay; Rectum; Sigmoidoscopy; Substance P

1989