substance p has been researched along with Carcinoma, Oat Cell in 32 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (25.00) | 18.7374 |
1990's | 20 (62.50) | 18.2507 |
2000's | 3 (9.38) | 29.6817 |
2010's | 1 (3.13) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Covenas, R; Munoz, M; Recio, S; Redondo, M; Rosso, M | 1 |
Haslett, C; MacKinnon, AC; Rossi, AG; Seckl, M; Sethi, T; Tufail-Hanif, U; Wheatley, M | 1 |
MacKinnon, A; Sethi, T | 1 |
Cummings, J; Haslett, C; Jodrell, D; MacKinnon, AC; Sethi, T; Tufail-Hanif, U; Waters, CM | 1 |
Osamura, RY; Tsutsumi, Y; Watanabe, K; Yanaihara, N | 1 |
Bleehen, NM; Reeve, JG | 1 |
Alford, C; Bunn, PA; Chan, D; Gera, L; Jewett, P; Mochzuki, T; Stewart, J; Tagawa, M; Tolley, R; Yanaihara, N | 1 |
Cummings, J; Langdon, SP; MacLellan, A; Smyth, JF | 1 |
Bartha, L; Nagy, J; Nyéki, O; Orosz, A; Schön, I; Schrett, J | 1 |
Cummings, J; Jones, DA; Langdon, SP; MacLellan, AJ; Rozengurt, E; Smyth, JF | 1 |
Schütte, J; Seeber, S | 1 |
Corrin, B; Hamid, Q; Milroy, C; Rode, J; Salim, SA | 1 |
Everard, MJ; Macaulay, VM; Millar, JL; Smith, IE | 1 |
Rozengurt, E; Seckl, MJ | 1 |
Chilvers, ER; Dransfield, I; Hannah, S; Haslett, C; Lawson, MF; Sethi, T; Tallett, A | 1 |
Higgins, T; Rozengurt, E; Seckl, MJ; Widmer, F | 1 |
Cummings, J; Jones, DA; Langdon, SP; MacLellan, AJ; Ritchie, AA; Smyth, JF | 1 |
Adil, MR; Ali, MA; Eliason, J; Kalemkerian, GP; Orosz, A; Rosati, R; Sebestyén, F | 1 |
Bartha, L; Nagy, J; Nyéki, O; Orosz, A; Rill, A; Schon, I; Schrett, J | 1 |
Chikumi, H; Hitsuda, Y; Kawasaki, Y; Kometani, Y; Matsumoto, S; Matsumoto, Y; Mikami, M; Nakamoto, M; Sasaki, T; Tokuyasu, H | 1 |
Heitz, P | 1 |
Everard, MJ; Macaulay, VM; Miller, JL; Smith, IE | 1 |
Langdon, S; Muir, M; Ritchie, A; Rozengurt, E; Sethi, T; Smyth, J | 1 |
Endoh, K; Kumada, M; Mukai, H; Munekata, E; Ohue, Y; Takuwa, N; Takuwa, Y; Yamashita, K | 1 |
Schwartz, TW; Vangsted, AJ | 1 |
Rozengurt, E; Woll, PJ | 2 |
Carney, DN; Cuttitta, F; Minna, JD; Moody, TW; Quattrocchi, K | 1 |
Pert, CB; Ruff, M; Schiffmann, E; Terranova, V | 1 |
Bepler, G; Carney, DN; Gazdar, AF; Minna, JD | 1 |
Fiskum, G; Mahmoud, S; Moody, TW; Murphy, A | 1 |
Layton, JE; Morstyn, G; Scanlon, DB; Soveny, C | 1 |
2 review(s) available for substance p and Carcinoma, Oat Cell
Article | Year |
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Bombesin antagonists: experimental and clinical results.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Bombesin; Carcinoma, Small Cell; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Molecular Sequence Data; Peptides; Signal Transduction; Structure-Activity Relationship; Substance P | 1993 |
[Endocrine system of the gut and the respiratory tract (author's transl)].
Topics: Appendiceal Neoplasms; Carcinoid Tumor; Carcinoma, Small Cell; Cholecystokinin; Digestive System; Duodenum; Endocrine Glands; Fetus; Gastric Mucosa; Gastrins; Humans; Ileum; Peptides; Rectal Neoplasms; Respiratory System; Secretin; Substance P; Vasoactive Intestinal Peptide | 1977 |
30 other study(ies) available for substance p and Carcinoma, Oat Cell
Article | Year |
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The antiproliferative action of [D-Arg(1), D-Phe(5), D-Trp(7,9), LEU(11)] substance P analogue antagonist against small-cell- and non-small-cell lung cancer cells could be due to the pharmacological profile of its tachykinin receptor antagonist.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Substance P | 2015 |
Targeting V1A-vasopressin receptors with [Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) identifies a strategy to develop novel anti-cancer therapies.
Topics: Animals; Antineoplastic Agents; Arginine Vasopressin; Calcium; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Extracellular Signal-Regulated MAP Kinases; Humans; Lung Neoplasms; Peptide Fragments; Pertussis Toxin; Receptors, Bombesin; Receptors, Vasopressin; Signal Transduction; Substance P; Type C Phospholipases | 2009 |
[D-Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism.
Topics: Apoptosis; Carcinoma, Small Cell; Cell Division; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Peptide Fragments; Precipitin Tests; Substance P; Time Factors; Tumor Cells, Cultured | 2003 |
Increased gastrin-releasing peptide (GRP) receptor expression in tumour cells confers sensitivity to [Arg6,D-Trp7,9,NmePhe8]-substance P (6-11)-induced growth inhibition.
Topics: Animals; Antineoplastic Agents; Bradykinin; Calcium; Carcinoma, Small Cell; Cell Division; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fibroblasts; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Mice; Mice, Nude; Peptide Fragments; Rats; Receptors, Bombesin; Receptors, Neuropeptide; Substance P; Transplantation, Heterologous; Tumor Cells, Cultured; Vasopressins | 2003 |
Immunohistochemical studies on gastrin-releasing peptide- and adrenocorticotropic hormone-containing cells in the human lung.
Topics: Adrenocorticotropic Hormone; Adult; Antibodies; Bombesin; Bronchi; Carcinoid Tumor; Carcinoma, Small Cell; Fetus; Gastrin-Releasing Peptide; Histocytochemistry; Humans; Immune Sera; Immunochemistry; Immunoenzyme Techniques; Infant; Infant, Newborn; Lung; Lung Neoplasms; Peptides; Pulmonary Fibrosis; Substance P | 1983 |
[D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P induces apoptosis in lung cancer cell lines in vitro.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Flow Cytometry; Humans; Kinetics; Lung Neoplasms; Substance P; Time Factors; Tumor Cells, Cultured | 1994 |
Effects of neuropeptide analogues on calcium flux and proliferation in lung cancer cell lines.
Topics: Amino Acid Sequence; Bombesin; Bradykinin; Calcium; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cholecystokinin; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Molecular Sequence Data; Neuropeptides; Peptides; Substance P; Tumor Cells, Cultured | 1994 |
Stability and in vitro metabolism of the mitogenic neuropeptide antagonists [D-Arg1,D-Phe5, D-Trp7,9, Leu11]-substance P and [Arg6, D-Trp7,9, MePhe8]-substance P (6-11) characterized by high-performance liquid chromatography.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Drug Stability; Half-Life; Humans; In Vitro Techniques; Liver; Mice; Mice, Nude; Molecular Sequence Data; Peptide Fragments; Substance P | 1994 |
New short-chain analogs of a substance-P antagonist inhibit proliferation of human small-cell lung-cancer cells in vitro and in vivo.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Bombesin; Carcinoma, Small Cell; Cell Division; Female; Humans; Kinetics; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Oligopeptides; Substance P; Transplantation, Heterologous; Tumor Cells, Cultured | 1995 |
Processing of the neuropeptide growth factor antagonist [Arg6, D-Trp7.9, NmePhe8]-substance P (6-11) by a small cell lung cancer cell line (H69).
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cell Line; Chromatography, High Pressure Liquid; Culture Media; Humans; Lung Neoplasms; Peptide Fragments; Substance P; Time Factors | 1995 |
Immunocytochemical characterization of neuroendocrine tumours of the larynx.
Topics: Adult; Aged; Aged, 80 and over; Bombesin; Calcitonin; Carcinoma; Carcinoma, Small Cell; Chromogranin A; Chromogranins; Enkephalin, Methionine; Female; Humans; Immunohistochemistry; Laryngeal Neoplasms; Male; Middle Aged; Neuropeptide Y; Neuropeptides; Neurosecretory Systems; Paraganglioma; Phosphopyruvate Hydratase; Somatostatin; Substance P | 1993 |
[D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P inhibits the growth of human small cell lung cancer xenografts in vivo.
Topics: Animals; Carcinoma, Small Cell; Drug Screening Assays, Antitumor; Growth Inhibitors; Humans; Injections, Subcutaneous; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Recombinant Proteins; Substance P; Time Factors; Transplantation, Heterologous | 1993 |
Effect of tyrphostin combined with a substance P related antagonist on small cell lung cancer cell growth in vitro.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lung Neoplasms; Neoplastic Stem Cells; Nitriles; Peptide Fragments; Protein-Tyrosine Kinases; Signal Transduction; Substance P; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrphostins | 1996 |
Inhibition of neuropeptide-stimulated tyrosine phosphorylation and tyrosine kinase activity stimulates apoptosis in small cell lung cancer cells.
Topics: Apoptosis; Bombesin; Carcinoma, Small Cell; Cell Adhesion Molecules; Cell Cycle; Cell Division; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Isoflavones; Kinetics; Lung Neoplasms; Necrosis; Neuropeptides; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Neuropeptide; Substance P; Time Factors; Tumor Cells, Cultured; Tyrphostins | 1996 |
[D-Arg1,D-Trp5,7,9,Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells.
Topics: Animals; Antineoplastic Agents; Calcium; Carcinoma, Small Cell; Cell Division; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Substance P; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1997 |
Processing of [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P in xenograft bearing Nu/Nu mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Female; Half-Life; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Substance P; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured | 1997 |
Induction of apoptosis by a short-chain neuropeptide analog in small cell lung cancer.
Topics: Antineoplastic Agents, Hormonal; Apoptosis; Carcinoma, Small Cell; Flow Cytometry; Lung Neoplasms; Microscopy, Fluorescence; Substance P | 1998 |
Synthesis of peptide and pseudopeptide amides inhibiting the proliferation of small cell and epithelial types of lung carcinoma cells.
Topics: 3T3 Cells; Amides; Amino Acid Sequence; Animals; Bombesin; Carcinoma, Small Cell; Cell Division; Humans; Hydrolysis; Lung Neoplasms; Mice; Molecular Sequence Data; Peptides; Substance P; Tumor Cells, Cultured | 1998 |
[Relationship between cancer chemotherapeutic drug-induced delayed emesis and plasma levels of substance P in two patients with small cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Small Cell; Cisplatin; Humans; Hydroxyindoleacetic Acid; Lung Neoplasms; Male; Serotonin; Serotonin Antagonists; Substance P; Vomiting, Anticipatory | 1999 |
In vitro effects of substance P analogue [D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P on human tumour and normal cell growth.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bombesin; Bone Marrow; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Cell Line; Colony-Forming Units Assay; DNA; Dose-Response Relationship, Drug; Female; Fibroblasts; Humans; In Vitro Techniques; Insulin-Like Growth Factor I; Lung Neoplasms; Ovarian Neoplasms; Substance P; Time Factors; Vasopressins | 1992 |
Broad spectrum neuropeptide antagonists inhibit the growth of small cell lung cancer in vivo.
Topics: Animals; Calcium; Carcinoma, Small Cell; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Peptide Fragments; Signal Transduction; Substance P; Tumor Cells, Cultured | 1992 |
Stimulation of calcium mobilization but not proliferation by bombesin and tachykinin neuropeptides in human small cell lung cancer cells.
Topics: Bombesin; Calcium; Carcinoma, Small Cell; Cell Division; DNA, Neoplasm; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Peptides; Substance P; Tachykinins; Tumor Cells, Cultured | 1990 |
Production of gastrin-releasing peptide-(18-27) and a stable fragment of its precursor in small cell lung carcinoma cells.
Topics: Amino Acid Sequence; Biomarkers, Tumor; Bombesin; Carcinoma, Small Cell; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromosome Mapping; Gastrin-Releasing Peptide; Gene Expression; Humans; Immunoradiometric Assay; In Vitro Techniques; Lung Neoplasms; Molecular Sequence Data; Peptide Fragments; Peptides; Sequence Homology, Nucleic Acid; Substance P | 1990 |
A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro.
Topics: Animals; Bradykinin; Calcium; Carcinoma, Small Cell; Cell Division; Cells, Cultured; DNA, Neoplasm; Drug Screening Assays, Antitumor; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Mice; Peptide Fragments; Peptides; Recombinant Proteins; Substance P; Tumor Cells, Cultured; Vasopressins | 1990 |
High affinity receptors for bombesin/GRP-like peptides on human small cell lung cancer.
Topics: Bombesin; Carcinoma, Small Cell; Cell Line; Chromatography, Affinity; Gastrin-Releasing Peptide; Humans; Kinetics; Lung Neoplasms; Peptides; Receptors, Bombesin; Receptors, Cell Surface; Substance P; Vasopressins | 1985 |
Neuropeptides are chemoattractants for human tumor cells and monocytes: a possible mechanism for metastasis.
Topics: Arginine Vasopressin; Bombesin; Carcinoma, Small Cell; Cell Adhesion; Chemotaxis; Chromosome Aberrations; Humans; Lung Neoplasms; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Metastasis; Neoplastic Stem Cells; Nerve Tissue Proteins; Neurotransmitter Agents; Substance P | 1985 |
In vitro growth inhibition of human small cell lung cancer by physalaemin.
Topics: Adrenocorticotropic Hormone; Arginine Vasopressin; Calcitonin; Carcinoma, Small Cell; Cell Division; Glucagon; Humans; Kassinin; Kinins; Neurotensin; Oligopeptides; Physalaemin; Somatostatin; Substance P | 1987 |
Bombesin-like peptides elevate cytosolic calcium in small cell lung cancer cells.
Topics: Benzofurans; Bombesin; Calcium; Carcinoma, Small Cell; Cell Line; Cytosol; Fura-2; Gastrin-Releasing Peptide; Humans; In Vitro Techniques; Oligopeptides; Peptides; Receptors, Bombesin; Receptors, Neurotransmitter; Somatostatin; Structure-Activity Relationship; Substance P; Vasoactive Intestinal Peptide | 1987 |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Bombesin; Carcinoma, Small Cell; DNA Replication; Epidermal Growth Factor; Gastrin-Releasing Peptide; Lung Neoplasms; Mice; Mitosis; Molecular Weight; Peptides; Substance P; Tumor Cells, Cultured | 1988 |
Effects of bombesin antagonists on the growth of small cell lung cancer cells in vitro.
Topics: Animals; Bombesin; Carcinoma, Small Cell; Gastrin-Releasing Peptide; Lung Neoplasms; Mice; Peptides; Receptors, Bombesin; Receptors, Neurotransmitter; Substance P; Tumor Cells, Cultured | 1988 |