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substance p and Carcinoma, Oat Cell

substance p has been researched along with Carcinoma, Oat Cell in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19908 (25.00)18.7374
1990's20 (62.50)18.2507
2000's3 (9.38)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Covenas, R; Munoz, M; Recio, S; Redondo, M; Rosso, M1
Haslett, C; MacKinnon, AC; Rossi, AG; Seckl, M; Sethi, T; Tufail-Hanif, U; Wheatley, M1
MacKinnon, A; Sethi, T1
Cummings, J; Haslett, C; Jodrell, D; MacKinnon, AC; Sethi, T; Tufail-Hanif, U; Waters, CM1
Osamura, RY; Tsutsumi, Y; Watanabe, K; Yanaihara, N1
Bleehen, NM; Reeve, JG1
Alford, C; Bunn, PA; Chan, D; Gera, L; Jewett, P; Mochzuki, T; Stewart, J; Tagawa, M; Tolley, R; Yanaihara, N1
Cummings, J; Langdon, SP; MacLellan, A; Smyth, JF1
Bartha, L; Nagy, J; Nyéki, O; Orosz, A; Schön, I; Schrett, J1
Cummings, J; Jones, DA; Langdon, SP; MacLellan, AJ; Rozengurt, E; Smyth, JF1
Schütte, J; Seeber, S1
Corrin, B; Hamid, Q; Milroy, C; Rode, J; Salim, SA1
Everard, MJ; Macaulay, VM; Millar, JL; Smith, IE1
Rozengurt, E; Seckl, MJ1
Chilvers, ER; Dransfield, I; Hannah, S; Haslett, C; Lawson, MF; Sethi, T; Tallett, A1
Higgins, T; Rozengurt, E; Seckl, MJ; Widmer, F1
Cummings, J; Jones, DA; Langdon, SP; MacLellan, AJ; Ritchie, AA; Smyth, JF1
Adil, MR; Ali, MA; Eliason, J; Kalemkerian, GP; Orosz, A; Rosati, R; Sebestyén, F1
Bartha, L; Nagy, J; Nyéki, O; Orosz, A; Rill, A; Schon, I; Schrett, J1
Chikumi, H; Hitsuda, Y; Kawasaki, Y; Kometani, Y; Matsumoto, S; Matsumoto, Y; Mikami, M; Nakamoto, M; Sasaki, T; Tokuyasu, H1
Heitz, P1
Everard, MJ; Macaulay, VM; Miller, JL; Smith, IE1
Langdon, S; Muir, M; Ritchie, A; Rozengurt, E; Sethi, T; Smyth, J1
Endoh, K; Kumada, M; Mukai, H; Munekata, E; Ohue, Y; Takuwa, N; Takuwa, Y; Yamashita, K1
Schwartz, TW; Vangsted, AJ1
Rozengurt, E; Woll, PJ2
Carney, DN; Cuttitta, F; Minna, JD; Moody, TW; Quattrocchi, K1
Pert, CB; Ruff, M; Schiffmann, E; Terranova, V1
Bepler, G; Carney, DN; Gazdar, AF; Minna, JD1
Fiskum, G; Mahmoud, S; Moody, TW; Murphy, A1
Layton, JE; Morstyn, G; Scanlon, DB; Soveny, C1

Reviews

2 review(s) available for substance p and Carcinoma, Oat Cell

ArticleYear
Bombesin antagonists: experimental and clinical results.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1993, Volume: 129

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Bombesin; Carcinoma, Small Cell; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Molecular Sequence Data; Peptides; Signal Transduction; Structure-Activity Relationship; Substance P

1993
[Endocrine system of the gut and the respiratory tract (author's transl)].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1977, Volume: 61

    Topics: Appendiceal Neoplasms; Carcinoid Tumor; Carcinoma, Small Cell; Cholecystokinin; Digestive System; Duodenum; Endocrine Glands; Fetus; Gastric Mucosa; Gastrins; Humans; Ileum; Peptides; Rectal Neoplasms; Respiratory System; Secretin; Substance P; Vasoactive Intestinal Peptide

1977

Other Studies

30 other study(ies) available for substance p and Carcinoma, Oat Cell

ArticleYear
The antiproliferative action of [D-Arg(1), D-Phe(5), D-Trp(7,9), LEU(11)] substance P analogue antagonist against small-cell- and non-small-cell lung cancer cells could be due to the pharmacological profile of its tachykinin receptor antagonist.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2015, Volume: 66, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Substance P

2015
Targeting V1A-vasopressin receptors with [Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) identifies a strategy to develop novel anti-cancer therapies.
    British journal of pharmacology, 2009, Volume: 156, Issue:1

    Topics: Animals; Antineoplastic Agents; Arginine Vasopressin; Calcium; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Extracellular Signal-Regulated MAP Kinases; Humans; Lung Neoplasms; Peptide Fragments; Pertussis Toxin; Receptors, Bombesin; Receptors, Vasopressin; Signal Transduction; Substance P; Type C Phospholipases

2009
[D-Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism.
    Methods in molecular medicine, 2003, Volume: 74

    Topics: Apoptosis; Carcinoma, Small Cell; Cell Division; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Peptide Fragments; Precipitin Tests; Substance P; Time Factors; Tumor Cells, Cultured

2003
Increased gastrin-releasing peptide (GRP) receptor expression in tumour cells confers sensitivity to [Arg6,D-Trp7,9,NmePhe8]-substance P (6-11)-induced growth inhibition.
    British journal of cancer, 2003, Jun-02, Volume: 88, Issue:11

    Topics: Animals; Antineoplastic Agents; Bradykinin; Calcium; Carcinoma, Small Cell; Cell Division; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fibroblasts; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Mice; Mice, Nude; Peptide Fragments; Rats; Receptors, Bombesin; Receptors, Neuropeptide; Substance P; Transplantation, Heterologous; Tumor Cells, Cultured; Vasopressins

2003
Immunohistochemical studies on gastrin-releasing peptide- and adrenocorticotropic hormone-containing cells in the human lung.
    Laboratory investigation; a journal of technical methods and pathology, 1983, Volume: 48, Issue:5

    Topics: Adrenocorticotropic Hormone; Adult; Antibodies; Bombesin; Bronchi; Carcinoid Tumor; Carcinoma, Small Cell; Fetus; Gastrin-Releasing Peptide; Histocytochemistry; Humans; Immune Sera; Immunochemistry; Immunoenzyme Techniques; Infant; Infant, Newborn; Lung; Lung Neoplasms; Peptides; Pulmonary Fibrosis; Substance P

1983
[D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P induces apoptosis in lung cancer cell lines in vitro.
    Biochemical and biophysical research communications, 1994, Mar-30, Volume: 199, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Flow Cytometry; Humans; Kinetics; Lung Neoplasms; Substance P; Time Factors; Tumor Cells, Cultured

1994
Effects of neuropeptide analogues on calcium flux and proliferation in lung cancer cell lines.
    Cancer research, 1994, Jul-01, Volume: 54, Issue:13

    Topics: Amino Acid Sequence; Bombesin; Bradykinin; Calcium; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cholecystokinin; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Molecular Sequence Data; Neuropeptides; Peptides; Substance P; Tumor Cells, Cultured

1994
Stability and in vitro metabolism of the mitogenic neuropeptide antagonists [D-Arg1,D-Phe5, D-Trp7,9, Leu11]-substance P and [Arg6, D-Trp7,9, MePhe8]-substance P (6-11) characterized by high-performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:6

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Drug Stability; Half-Life; Humans; In Vitro Techniques; Liver; Mice; Mice, Nude; Molecular Sequence Data; Peptide Fragments; Substance P

1994
New short-chain analogs of a substance-P antagonist inhibit proliferation of human small-cell lung-cancer cells in vitro and in vivo.
    International journal of cancer, 1995, Jan-03, Volume: 60, Issue:1

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Bombesin; Carcinoma, Small Cell; Cell Division; Female; Humans; Kinetics; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Oligopeptides; Substance P; Transplantation, Heterologous; Tumor Cells, Cultured

1995
Processing of the neuropeptide growth factor antagonist [Arg6, D-Trp7.9, NmePhe8]-substance P (6-11) by a small cell lung cancer cell line (H69).
    Biochemical pharmacology, 1995, May-26, Volume: 49, Issue:11

    Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cell Line; Chromatography, High Pressure Liquid; Culture Media; Humans; Lung Neoplasms; Peptide Fragments; Substance P; Time Factors

1995
Immunocytochemical characterization of neuroendocrine tumours of the larynx.
    Histopathology, 1993, Volume: 23, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Bombesin; Calcitonin; Carcinoma; Carcinoma, Small Cell; Chromogranin A; Chromogranins; Enkephalin, Methionine; Female; Humans; Immunohistochemistry; Laryngeal Neoplasms; Male; Middle Aged; Neuropeptide Y; Neuropeptides; Neurosecretory Systems; Paraganglioma; Phosphopyruvate Hydratase; Somatostatin; Substance P

1993
[D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P inhibits the growth of human small cell lung cancer xenografts in vivo.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:10

    Topics: Animals; Carcinoma, Small Cell; Drug Screening Assays, Antitumor; Growth Inhibitors; Humans; Injections, Subcutaneous; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Recombinant Proteins; Substance P; Time Factors; Transplantation, Heterologous

1993
Effect of tyrphostin combined with a substance P related antagonist on small cell lung cancer cell growth in vitro.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:2

    Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lung Neoplasms; Neoplastic Stem Cells; Nitriles; Peptide Fragments; Protein-Tyrosine Kinases; Signal Transduction; Substance P; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrphostins

1996
Inhibition of neuropeptide-stimulated tyrosine phosphorylation and tyrosine kinase activity stimulates apoptosis in small cell lung cancer cells.
    Cancer research, 1996, Sep-15, Volume: 56, Issue:18

    Topics: Apoptosis; Bombesin; Carcinoma, Small Cell; Cell Adhesion Molecules; Cell Cycle; Cell Division; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Isoflavones; Kinetics; Lung Neoplasms; Necrosis; Neuropeptides; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Neuropeptide; Substance P; Time Factors; Tumor Cells, Cultured; Tyrphostins

1996
[D-Arg1,D-Trp5,7,9,Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells.
    Cancer research, 1997, Jan-01, Volume: 57, Issue:1

    Topics: Animals; Antineoplastic Agents; Calcium; Carcinoma, Small Cell; Cell Division; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Substance P; Tumor Cells, Cultured; Tumor Stem Cell Assay

1997
Processing of [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P in xenograft bearing Nu/Nu mice.
    Peptides, 1997, Volume: 18, Issue:7

    Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Female; Half-Life; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Substance P; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured

1997
Induction of apoptosis by a short-chain neuropeptide analog in small cell lung cancer.
    Peptides, 1998, Volume: 19, Issue:9

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; Carcinoma, Small Cell; Flow Cytometry; Lung Neoplasms; Microscopy, Fluorescence; Substance P

1998
Synthesis of peptide and pseudopeptide amides inhibiting the proliferation of small cell and epithelial types of lung carcinoma cells.
    Journal of peptide science : an official publication of the European Peptide Society, 1998, Volume: 4, Issue:8

    Topics: 3T3 Cells; Amides; Amino Acid Sequence; Animals; Bombesin; Carcinoma, Small Cell; Cell Division; Humans; Hydrolysis; Lung Neoplasms; Mice; Molecular Sequence Data; Peptides; Substance P; Tumor Cells, Cultured

1998
[Relationship between cancer chemotherapeutic drug-induced delayed emesis and plasma levels of substance P in two patients with small cell lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Small Cell; Cisplatin; Humans; Hydroxyindoleacetic Acid; Lung Neoplasms; Male; Serotonin; Serotonin Antagonists; Substance P; Vomiting, Anticipatory

1999
In vitro effects of substance P analogue [D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P on human tumour and normal cell growth.
    British journal of cancer, 1992, Volume: 65, Issue:3

    Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bombesin; Bone Marrow; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Cell Line; Colony-Forming Units Assay; DNA; Dose-Response Relationship, Drug; Female; Fibroblasts; Humans; In Vitro Techniques; Insulin-Like Growth Factor I; Lung Neoplasms; Ovarian Neoplasms; Substance P; Time Factors; Vasopressins

1992
Broad spectrum neuropeptide antagonists inhibit the growth of small cell lung cancer in vivo.
    Cancer research, 1992, Aug-15, Volume: 52, Issue:16

    Topics: Animals; Calcium; Carcinoma, Small Cell; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Peptide Fragments; Signal Transduction; Substance P; Tumor Cells, Cultured

1992
Stimulation of calcium mobilization but not proliferation by bombesin and tachykinin neuropeptides in human small cell lung cancer cells.
    Cancer research, 1990, Jan-15, Volume: 50, Issue:2

    Topics: Bombesin; Calcium; Carcinoma, Small Cell; Cell Division; DNA, Neoplasm; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Peptides; Substance P; Tachykinins; Tumor Cells, Cultured

1990
Production of gastrin-releasing peptide-(18-27) and a stable fragment of its precursor in small cell lung carcinoma cells.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 70, Issue:6

    Topics: Amino Acid Sequence; Biomarkers, Tumor; Bombesin; Carcinoma, Small Cell; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromosome Mapping; Gastrin-Releasing Peptide; Gene Expression; Humans; Immunoradiometric Assay; In Vitro Techniques; Lung Neoplasms; Molecular Sequence Data; Peptide Fragments; Peptides; Sequence Homology, Nucleic Acid; Substance P

1990
A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro.
    Cancer research, 1990, Jul-01, Volume: 50, Issue:13

    Topics: Animals; Bradykinin; Calcium; Carcinoma, Small Cell; Cell Division; Cells, Cultured; DNA, Neoplasm; Drug Screening Assays, Antitumor; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Mice; Peptide Fragments; Peptides; Recombinant Proteins; Substance P; Tumor Cells, Cultured; Vasopressins

1990
High affinity receptors for bombesin/GRP-like peptides on human small cell lung cancer.
    Life sciences, 1985, Jul-15, Volume: 37, Issue:2

    Topics: Bombesin; Carcinoma, Small Cell; Cell Line; Chromatography, Affinity; Gastrin-Releasing Peptide; Humans; Kinetics; Lung Neoplasms; Peptides; Receptors, Bombesin; Receptors, Cell Surface; Substance P; Vasopressins

1985
Neuropeptides are chemoattractants for human tumor cells and monocytes: a possible mechanism for metastasis.
    Clinical immunology and immunopathology, 1985, Volume: 37, Issue:3

    Topics: Arginine Vasopressin; Bombesin; Carcinoma, Small Cell; Cell Adhesion; Chemotaxis; Chromosome Aberrations; Humans; Lung Neoplasms; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Metastasis; Neoplastic Stem Cells; Nerve Tissue Proteins; Neurotransmitter Agents; Substance P

1985
In vitro growth inhibition of human small cell lung cancer by physalaemin.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adrenocorticotropic Hormone; Arginine Vasopressin; Calcitonin; Carcinoma, Small Cell; Cell Division; Glucagon; Humans; Kassinin; Kinins; Neurotensin; Oligopeptides; Physalaemin; Somatostatin; Substance P

1987
Bombesin-like peptides elevate cytosolic calcium in small cell lung cancer cells.
    Biochemical and biophysical research communications, 1987, Aug-31, Volume: 147, Issue:1

    Topics: Benzofurans; Bombesin; Calcium; Carcinoma, Small Cell; Cell Line; Cytosol; Fura-2; Gastrin-Releasing Peptide; Humans; In Vitro Techniques; Oligopeptides; Peptides; Receptors, Bombesin; Receptors, Neurotransmitter; Somatostatin; Structure-Activity Relationship; Substance P; Vasoactive Intestinal Peptide

1987
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:6

    Topics: Amino Acid Sequence; Animals; Binding, Competitive; Bombesin; Carcinoma, Small Cell; DNA Replication; Epidermal Growth Factor; Gastrin-Releasing Peptide; Lung Neoplasms; Mice; Mitosis; Molecular Weight; Peptides; Substance P; Tumor Cells, Cultured

1988
Effects of bombesin antagonists on the growth of small cell lung cancer cells in vitro.
    Cancer research, 1988, Sep-01, Volume: 48, Issue:17

    Topics: Animals; Bombesin; Carcinoma, Small Cell; Gastrin-Releasing Peptide; Lung Neoplasms; Mice; Peptides; Receptors, Bombesin; Receptors, Neurotransmitter; Substance P; Tumor Cells, Cultured

1988