Page last updated: 2024-08-23

substance p and Bronchial Hyperreactivity

substance p has been researched along with Bronchial Hyperreactivity in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	32 (59.26)	18.2507
2000's	18 (33.33)	29.6817
2010's	4 (7.41)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bullens, DM; Cadot, P; Callebaut, I; Ceuppens, JL; Hellings, PW; Hens, G; Meyts, I; Nemery, B; Raap, U; Vanaudenaerde, BM; Vanoirbeek, J; Verbinnen, B	1
Fryer, AD; Hazari, MS; Jacoby, DB; Jacoby, IW; Moulton, BC; Verhein, KC	1
Fang, LP; Li, SJ; Li, ZC; Lin, HJ; Qi, HW; Xie, BM	1
Almeida, J; Beltrão, M; Costa, R; Delgado, L; Guardão, L; Guimarães, JT; Moreira, A; Palmares, C; Pirraco, A; Ramalho, R; Soares, R; Sokhatska, O	1
Alpizar, YA; Bobic, S; Braun, A; Bullens, DM; Callebaut, I; Ceuppens, JL; De Vooght, V; De Vries, A; Devos, F; Hellings, PW; Hoet, P; Hox, V; Liston, A; Nemery, B; Sharify, A; Talavera, K; Van Gerven, L; Vanoirbeek, JA; Vennekens, R; Voedisch, S; Voets, T	1
Dey, RD; Fedan, JS; Satterfield, BE; Wu, ZX	1
Braun, A; Dinh, QT; Fischer, A; Groneberg, DA; Kerzel, S; Nockher, WA; Päth, G; Quarcoo, D; Raap, U; Renz, H	1
Kendig, JJ; Peters, MC; Sweitzer, SM; Wong, SME	1
DeHate, RB; Richards, IS	1
Guan, C; Luo, Z; Qi, M; Qin, X; Wu, H; Xiang, Y; Zhang, C	1
Arck, PC; Cifuentes, LB; Dinh, QT; Fischer, A; Hagen, E; Joachim, RA; Klapp, BF; Quarcoo, D; Sagach, V	1
Braun, A; de Vries, A; Dessing, MC; Engels, F; Fischer, A; Groneberg, DA; Henricks, PA; Leusink-Muis, T; McGregor, GP; Nijkamp, FP	1
Börzsei, R; Elekes, K; Helyes, Z; Kereskai, L; Németh, J; Pintér, E; Pozsgai, G; Sándor, K; Szabó, A; Szolcsányi, J	1
Busso, N; Grouzmann, E; Lacroix, JS; Landis, BN; Monod, M; Morel, DR; Petak, F; Robert, JH; Spiliopoulos, A; Szalay-Quinodoz, I	1
Haraguchi, R; Iwanaga, T; Kubo, H; Muraki, M; Tohda, Y	1
Bendele, AM; Cockerham, SL; Silbaugh, SA; Stengel, PW	2
Cheung, D; den Hartigh, J; Dijkman, JH; Sterk, PJ; van der Veen, H	1
Gairola, CG; Lai, YL; Thacker, A	1
Desmazes-Dufeu, N; Dusser, DJ; Lacroix, H; Mordelet-Dambrine, M; Roisman, GL	1
Chiba, Y; Misawa, M	1
Chodimella, V; Lang, Z; Murlas, CG	1
Barnes, PJ; Chung, KF; Elwood, W; Lötvall, JO	1
Garland, A; Hershenson, MB; Hsiue, TR; Leff, AR; Ray, DW; Solway, J	1
Germonpré, PR; Joos, GF; Kips, JC; Pauwels, RA	1
Fujimura, M; Matsuda, T; Matsushima, K; Mizuguchi, M; Nomura, M; Tsujiura, M	1
Fattah, D; Hofman, G; Nijkamp, FP; van Ark, I; Van Der Linde, HJ; Van Oosterhout, AJ	1
Advenier, C; Biyah, K; Boichot, E; Emonds-Alt, X; Germain, N; Lagente, V	1
Belvisi, M	1
Fujimura, M; Ishiura, Y; Matsuda, T; Myou, S; Tsujiura, M	1
Kraneveld, AD; Nijkamp, FP; Van Oosterhout, AJ	1
Lee, LY; Morton, RF; Wu, ZX	1
Gustin, P; Montaño, LM; Romero, L; Sommer, B; Vargas, MH; Zamudio, P	1
Hisada, T; Iwamae, S; Mori, M; Tsukagoshi, H; Uno, D	1
Endoh, N; Ichinose, M; Kageyama, N; Mashito, Y; Miura, M; Ohuchi, Y; Shirato, K; Sugiura, H; Tomaki, M	1
Minc, P; Szmidt, M	1
Hirata, K; Kanazawa, H; Yoshikawa, J	1
Belmonte, KE; Costello, RW; Evans, CM; Fryer, AD; Gleich, GJ; Jacoby, DB	1
Bergren, DR	1
Hsu, TH; Kou, YR	1
Barone, FC; Bush, B; Foley, JJ; Giardina, GA; Griswold, DE; Grugni, M; Hay, DW; Kilian, D; Kotzer, CJ; Legos, JJ; Lundberg, D; Luttmann, MA; Martin, LD; Potts, W; Raveglia, LF; Sandhu, P; Sarau, HM; Schmidt, DB; Underwood, DC	1
Liu, L; Liu, Y; Ren, J; Wang, F; Wu, S; Yu, H	1
Apostoliti, F; Breschi, MC; Martinotti, E; Nieri, P	1
Carini, F; Catalioto, RM; Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P; Tramontana, M	1
Horvath, P; Kovács, P; Németh, J; Sziklai, I; Szilasi, M; Szilvássy, J; Szilvássy, Z	1
Breschi, MC; Daffonchio, L; Martinotti, E; Nieri, P; Omini, C	1
Ben-Jebria, A; Marthan, R; Savineau, JP	1
Harf, A; Jarreau, PH; Lambré, CR; Levame, M; Lorino, H; Macquin-Mavier, I	1
Darley-Usmar, V; O'Leary, VJ; Payne, AN; Wilkinson, D; Yeadon, M	1
Boomsma, JD; Said, SI	1
Selig, W; Tocker, J	1
Campos, MG; Montaño, LM; Ponce-Monter, H; Segura, P; Selman, M; Vanda, B; Vargas, MH	1
Inoue, H	1
Baas, AA; Evers, NA; van der Meer, C	1

Reviews

3 review(s) available for substance p and Bronchial Hyperreactivity

Article	Year
Beta-blocker induced asthma: a role for sensory nerve hyperresponsiveness? Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1996, Volume: 26, Issue:12 Topics: Adrenergic beta-Antagonists; Animals; Asthma; Bronchial Hyperreactivity; Guinea Pigs; Humans; Neurokinin A; Neurons, Afferent; Substance P	1996
[Cough, bronchoconstriction and bronchial hyperreactivity in relation to treatment with angiotensin-converting enzyme]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999, Volume: 6, Issue:35 Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bronchial Hyperreactivity; Bronchial Spasm; Cough; Histamine; Humans; Prostaglandins; Substance P	1999
The role of neuropeptides in asthma. Chest, 1992, Volume: 101, Issue:6 Suppl Topics: Administration, Inhalation; Asthma; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Endothelins; Humans; Neuropeptides; Substance P; Vasoactive Intestinal Peptide	1992

Trials

1 trial(s) available for substance p and Bronchial Hyperreactivity

Article	Year
Effects of inhaled substance P on airway responsiveness to methacholine in asthmatic subjects in vivo. Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:3 Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Substance P	1994

Article

Year

Effects of inhaled substance P on airway responsiveness to methacholine in asthmatic subjects in vivo.

Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:3

Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Substance P

1994

Other Studies

50 other study(ies) available for substance p and Bronchial Hyperreactivity

Article	Year
Selective nasal allergen provocation induces substance P-mediated bronchial hyperresponsiveness. American journal of respiratory cell and molecular biology, 2011, Volume: 44, Issue:4 Topics: Administration, Inhalation; Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Immunization; Leukocyte Count; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Nasal Provocation Tests; Neurokinin-1 Receptor Antagonists; Ovalbumin; Receptors, Neurokinin-1; Substance P; Tryptophan; Up-Regulation	2011
Three days after a single exposure to ozone, the mechanism of airway hyperreactivity is dependent on substance P and nerve growth factor. American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 300, Issue:2 Topics: Air Pollutants; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Female; Guinea Pigs; Humans; Lung; Male; Models, Biological; Nerve Growth Factor; Neurokinin-1 Receptor Antagonists; Ozone; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Time Factors; Vagus Nerve	2011
[To explore the mechanisms of neurogenic inflammation and airway hyperresponsiveness of rat by inhaled sulfur]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2009, Volume: 25, Issue:1 Topics: Air Pollutants; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Male; Nerve Fibers; Neurogenic Inflammation; Random Allocation; Rats; Rats, Sprague-Dawley; Substance P; Sulfur Dioxide	2009
Substance P antagonist improves both obesity and asthma in a mouse model. Allergy, 2013, Volume: 68, Issue:1 Topics: Allergens; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Bronchitis; Disease Models, Animal; Mice; Neurokinin-1 Receptor Antagonists; Obesity; Substance P	2013
Crucial role of transient receptor potential ankyrin 1 and mast cells in induction of nonallergic airway hyperreactivity in mice. American journal of respiratory and critical care medicine, 2013, Mar-01, Volume: 187, Issue:5 Topics: Animals; Bronchial Hyperreactivity; Cells, Cultured; Hypochlorous Acid; Irritants; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Knockout; Neuroimmunomodulation; Nociceptors; Ovalbumin; Substance P; Transient Receptor Potential Channels; TRPA1 Cation Channel	2013
Interleukin-1beta-induced airway hyperresponsiveness enhances substance P in intrinsic neurons of ferret airway. American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 283, Issue:5 Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Disease Models, Animal; Electric Stimulation; Ferrets; Instillation, Drug; Interleukin-1; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Neurons; Substance P; Trachea	2002
Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma. American journal of respiratory cell and molecular biology, 2003, Volume: 28, Issue:2 Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Immunohistochemistry; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factors; Neurons; Ovalbumin; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Respiratory System; Substance P	2003
Hyperresponsiveness on washout of volatile anesthetics from isolated spinal cord compared to withdrawal from ethanol. Anesthesia and analgesia, 2005, Volume: 100, Issue:2 Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Electric Stimulation; Enzyme Inhibitors; Ethanol; Excitatory Postsynaptic Potentials; Glutamic Acid; Indoles; Maleimides; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Substance Withdrawal Syndrome	2005
Formalin produces depolarizations in human airway smooth muscle in vitro. Toxicology and industrial health, 2006, Volume: 22, Issue:2 Topics: Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Electrophysiology; Formaldehyde; Humans; In Vitro Techniques; Irritants; Membrane Potentials; Muscle, Smooth; Neuromuscular Depolarizing Agents; Substance P; Trachea	2006
Upregulation of substance P receptor expression by calcitonin gene-related peptide, a possible cooperative action of two neuropeptides involved in airway inflammation. Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:5 Topics: Animals; Asthma; Blotting, Western; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Guinea Pigs; Humans; Inflammation; Lung; Ozone; Protein-Tyrosine Kinases; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Substance P; Up-Regulation	2007
Stress induces substance P in vagal sensory neurons innervating the mouse airways. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:8 Topics: Allergens; Animals; Biomarkers; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Immunohistochemistry; Lung; Mice; Mice, Inbred BALB C; Models, Animal; Neural Pathways; Neurons, Afferent; Nodose Ganglion; Ovalbumin; Protein Precursors; Respiratory Hypersensitivity; Reverse Transcriptase Polymerase Chain Reaction; Stress, Psychological; Substance P; Tachykinins; Ubiquitin Thiolesterase	2006
Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:9 Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbazoles; Disease Models, Animal; Enzyme Inhibitors; Female; Guinea Pigs; Immunohistochemistry; Indole Alkaloids; Lung; Male; Nerve Growth Factor; Neurons; Nodose Ganglion; Ovalbumin; Receptor, trkA; Signal Transduction; Substance P; Tyrphostins	2006
Role of capsaicin-sensitive afferents and sensory neuropeptides in endotoxin-induced airway inflammation and consequent bronchial hyperreactivity in the mouse. Regulatory peptides, 2007, Jun-07, Volume: 141, Issue:1-3 Topics: Animals; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Capsaicin; Endotoxins; Enzyme-Linked Immunosorbent Assay; Female; Histocytochemistry; Inflammation; Interleukin-1beta; Lung; Mice; Mice, Inbred C57BL; Neurons, Afferent; Neuropeptides; Peroxidase; Radioimmunoassay; Somatostatin; Spectrophotometry; Substance P	2007
Implication of dipeptidylpeptidase IV activity in human bronchial inflammation and in bronchoconstriction evaluated in anesthetized rabbits. Respiration; international review of thoracic diseases, 2008, Volume: 75, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Animals; Biomarkers; Bronchial Hyperreactivity; Bronchitis, Chronic; Bronchoconstriction; Dipeptidyl Peptidase 4; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Histamine; Humans; Immunohistochemistry; Male; Middle Aged; Nasal Mucosa; Probability; Rabbits; Reference Values; Sampling Studies; Sensitivity and Specificity; Severity of Illness Index; Substance P	2008
Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs. International immunopharmacology, 2008, Volume: 8, Issue:5 Topics: Administration, Inhalation; Anesthetics, Local; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Cough; Eosinophils; Guinea Pigs; Histamine; Inflammation; Lidocaine; Lung; Male; Ovalbumin; Substance P	2008
Sulfuric acid induces airway hyperresponsiveness to substance P in the guinea pig. Agents and actions, 1993, Volume: 39 Spec No Topics: Administration, Inhalation; Animals; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Substance P; Sulfuric Acids; Thiorphan	1993
Effect of dexamethasone on A23187-induced airway responses in the guinea pig. European journal of pharmacology, 1994, Mar-03, Volume: 253, Issue:3 Topics: Administration, Inhalation; Administration, Oral; Airway Obstruction; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchial Spasm; Calcimycin; Dexamethasone; Dyspnea; Guinea Pigs; Lung; Male; Pulmonary Gas Exchange; Substance P	1994
Sidestream cigarette smoke exposure and airway reactivity during early life. Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:4 Topics: Acetylcholine; Animals; Animals, Newborn; Body Weight; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Female; Guinea Pigs; Maximal Expiratory Flow-Volume Curves; Pilot Projects; Pregnancy; Prenatal Exposure Delayed Effects; Respiration; Substance P; Tobacco Smoke Pollution	1994
Nedocromil sodium reduces cigarette smoke-induced bronchoconstrictor hyperresponsiveness to substance P in the guinea-pig. The European respiratory journal, 1995, Volume: 8, Issue:1 Topics: Aerosols; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Lung; Male; Nedocromil; Neprilysin; Substance P; Tobacco Smoke Pollution	1995
Inhibition of neutral endopeptidase increases airway responsiveness to ACh in nonsensitized normal rats. Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:2 Topics: Acetylcholine; Administration, Inhalation; Animals; Bronchial Hyperreactivity; Capillary Permeability; Capsaicin; Carbachol; Glycopeptides; In Vitro Techniques; Male; Muscle, Smooth; Neprilysin; Neurokinin A; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Respiratory System; Substance P; Vagotomy	1995
Dexamethasone reduces tachykinin but not ACh airway hyperreactivity after O3. Lung, 1993, Volume: 171, Issue:2 Topics: Acetylcholine; Airway Resistance; Animals; Anti-Bacterial Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Guinea Pigs; Male; Neprilysin; Oligopeptides; Ozone; Peptides; Substance P; Tachykinins	1993
Airway hyperresponsiveness to acetylcholine and to tachykinins after respiratory virus infection in the guinea pig. Annals of allergy, 1993, Volume: 70, Issue:3 Topics: Acetylcholine; Animals; Atropine; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Electric Stimulation; Guinea Pigs; Male; Parainfluenza Virus 1, Human; Paramyxoviridae Infections; Respiratory Tract Infections; Substance P; Tachykinins; Vagus Nerve	1993
Impaired sensorineural function after allergen-induced mediator release. The American review of respiratory disease, 1993, Volume: 148, Issue:2 Topics: Acetylcholine; Airway Resistance; Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Carbon Dioxide; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Male; Neurokinin A; Neurotransmitter Agents; Ovalbumin; Respiration Disorders; Substance P; Tidal Volume	1993
Genetic control of indirect airway responsiveness in the rat. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25 Suppl 2 Topics: Adenosine; Animals; Atropine; Blood Proteins; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Capillary Permeability; Capsaicin; Male; Methysergide; Nedocromil; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Tachykinin; Respiratory Function Tests; Serotonin; Serotonin Antagonists; Specific Pathogen-Free Organisms; Substance P; Tachykinins	1995
Sensory neuropeptides are not directly involved in bronchial hyperresponsiveness induced by interleukin-8 in guinea-pigs in vivo. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1996, Volume: 26, Issue:3 Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dipeptides; Guinea Pigs; Histamine; Indoles; Interleukin-8; Male; Neurokinin A; Peptides, Cyclic; Substance P	1996
Role of interleukin-5 and substance P in development of airway hyperreactivity to histamine in guinea-pigs. The European respiratory journal, 1996, Volume: 9, Issue:3 Topics: Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Drug Interactions; Eosinophils; Guinea Pigs; Histamine; Interleukin-5; Male; Peroxidase; Substance P; Trachea	1996
Involvement of tachykinin NK1 and NK2 receptors in substance P-induced microvascular leakage hypersensitivity and airway hyperresponsiveness in guinea-pigs. The European respiratory journal, 1996, Volume: 9, Issue:7 Topics: Animals; Benzamides; Bronchial Hyperreactivity; Capillary Leak Syndrome; Female; Glycopeptides; Guinea Pigs; Male; Metalloendopeptidases; Neurokinin-1 Receptor Antagonists; Piperidines; Premedication; Quinuclidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Stereoisomerism; Substance P	1996
Role of sensory neuropeptides in post-allergic propranolol-induced bronchoconstriction in guinea pigs in vivo. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1996, Volume: 26, Issue:12 Topics: Adrenergic beta-Antagonists; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Dipeptides; Guinea Pigs; Indoles; Male; Neurokinin A; Peptides, Cyclic; Propranolol; Substance P	1996
Role for neurokinin-2 receptor in interleukin-5-induced airway hyperresponsiveness but not eosinophilia in guinea pigs. American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:2 Pt 1 Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dipeptides; Eosinophilia; Eosinophils; Guinea Pigs; Indoles; Interleukin-5; Leukocyte Count; Male; Peptides, Cyclic; Receptors, Neurokinin-2; Specific Pathogen-Free Organisms; Substance P	1997
Role of tachykinins in ozone-induced airway hyperresponsiveness to cigarette smoke in guinea pigs. Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:3 Topics: Acetylcholine; Animals; Blood Pressure; Bronchi; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Ozone; Receptors, Neurokinin-2; Respiratory Mechanics; Substance P; Tachykinins; Tobacco Smoke Pollution	1997
Chronic exposure to ozone causes tolerance to airway hyperresponsiveness in guinea pigs: lack of SOD role. Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:5 Topics: Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage; Cell Count; Glycopeptides; Guinea Pigs; Inflammation; Infusions, Intravenous; Insufflation; Leukocytes; Lung; Macrophages; Male; Ozone; Substance P; Superoxide Dismutase	1998
A possible involvement of oxidative lung injury in endotoxin-induced bronchial hyperresponsiveness to substance P in guinea pigs. Toxicology and applied pharmacology, 1998, Volume: 151, Issue:2 Topics: Acetophenones; Aminophylline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchial Hyperreactivity; Drug Hypersensitivity; Endotoxins; Enzyme Inhibitors; Guinea Pigs; Hypochlorous Acid; Leukocytes; Lipid Peroxides; Lung; Male; Neprilysin; Oxidative Stress; Papaverine; Phosphoric Diester Hydrolases; Purinones; Reactive Oxygen Species; Substance P	1998
Induction of nitric oxide synthase by lipopolysaccharide inhalation enhances substance P-induced microvascular leakage in guinea-pigs. The European respiratory journal, 1998, Volume: 12, Issue:4 Topics: Administration, Inhalation; Analysis of Variance; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Capillary Leak Syndrome; Capillary Permeability; Disease Models, Animal; Evans Blue; Guinea Pigs; Lipopolysaccharides; Male; Nitric Oxide Synthase; Probability; Reference Values; Substance P	1998
Administration of SIN-1 induces guinea pig airway hyperresponsiveness through inactivation of airway neutral endopeptidase. International archives of allergy and immunology, 1999, Volume: 120, Issue:4 Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Endothelin-1; Enzyme Activation; Glycopeptides; Guinea Pigs; Male; Molsidomine; Neprilysin; Nitrates; Oxidants; Protease Inhibitors; Respiratory System; Substance P; Trachea; Vasodilator Agents	1999
Substance P-induced airway hyperreactivity is mediated by neuronal M(2) receptor dysfunction. American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:3 Topics: Animals; Antibodies; Blood Proteins; Bronchial Hyperreactivity; Cyclophosphamide; Electric Stimulation; Eosinophil Granule Proteins; Female; Guinea Pigs; Heparin; Neurokinin-1 Receptor Antagonists; Neurons; Piperidines; Quinuclidines; Receptor, Muscarinic M2; Receptors, Muscarinic; Ribonucleases; Substance P; Vagus Nerve	2000
Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs. Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 90, Issue:2 Topics: Administration, Inhalation; Airway Resistance; Animals; Bradykinin; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Guinea Pigs; Histamine; Leukocyte Count; Lung; Male; Methacholine Chloride; Neurokinin A; Ovalbumin; Peptide Fragments; Smoking; Substance P; Wakefulness	2001
Airway hyperresponsiveness to bronchoconstrictor challenge after wood smoke exposure in guinea pigs. Life sciences, 2001, May-18, Volume: 68, Issue:26 Topics: Acetylcholine; Airway Resistance; Animals; Blood Pressure; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Capsaicin; Dinoprost; Guinea Pigs; Histamine; Injections, Intravenous; Lung; Male; Respiratory Mechanics; Smoke; Substance P; Wood	2001
Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:1 Topics: Acetates; Animals; Antitussive Agents; Behavior, Animal; Bronchial Hyperreactivity; Calcium; Central Nervous System; Citric Acid; Cloning, Molecular; Cough; Guinea Pigs; In Vitro Techniques; Iris; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Pupil; Quinolines; Rabbits; Radioligand Assay; Rats; Receptors, Neurokinin-3; Receptors, Tachykinin; Recombinant Proteins; Substance P	2002
[P-selectin and tachykinins in bronchial hyperresponsiveness of asthma]. Zhonghua nei ke za zhi, 1999, Volume: 38, Issue:4 Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Glucocorticoids; Humans; Male; Middle Aged; P-Selectin; Substance P; Tachykinins; Vasoactive Intestinal Peptide	1999
Protective effect of silymarin in antigen challenge- and histamine-induced bronchoconstriction in in vivo guinea-pigs. European journal of pharmacology, 2002, Feb-15, Volume: 437, Issue:1-2 Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Protective Agents; Silymarin; Substance P; Time Factors	2002
Role of tachykinins in sephadex-induced airway hyperreactivity and inflammation in guinea pigs. European journal of pharmacology, 2002, Mar-29, Volume: 439, Issue:1-3 Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Cell Count; Cyclohexylamines; Dextrans; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Indoles; Inflammation; Macrophages; Male; Neurokinin A; Peptides, Cyclic; Receptors, Tachykinin; Substance P; Tachykinins; Time Factors; Vasodilator Agents	2002
Feeble bronchomotor responses in diabetic rats in association with decreased sensory neuropeptide release. American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 282, Issue:5 Topics: Animals; Blood Glucose; Body Weight; Bronchial Hyperreactivity; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Guinea Pigs; Insulin; Male; Neural Conduction; Neurons, Afferent; Ovalbumin; Rats; Rats, Wistar; Somatostatin; Substance P; Trachea	2002
Changes in airway reactivity to exogenous and endogenous acetylcholine and substance P after anaphylactic bronchoconstriction in anaesthetized guinea-pigs. Journal of autonomic pharmacology, 1992, Volume: 12, Issue:6 Topics: Acetylcholine; Anaphylaxis; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Male; Substance P; Vagus Nerve	1992
Effect of in vitro nitrogen dioxide exposure on human bronchial smooth muscle response. The American review of respiratory disease, 1992, Volume: 146, Issue:2 Topics: Acetylcholine; Airway Resistance; Bronchial Hyperreactivity; Bronchial Provocation Tests; Carbachol; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Histamine; Humans; In Vitro Techniques; Nitrogen Dioxide; Substance P	1992
Effects of neuraminidase on airway reactivity in the guinea pig. The American review of respiratory disease, 1992, Volume: 145, Issue:4 Pt 1 Topics: Albuterol; Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Guinea Pigs; Male; Neprilysin; Neuraminidase; Orthomyxoviridae Infections; Paramyxoviridae Infections; Substance P; Vibrio cholerae	1992
Mechanisms contributing to ozone-induced bronchial hyperreactivity in guinea-pigs. Pulmonary pharmacology, 1992, Volume: 5, Issue:1 Topics: Adenine Nucleotides; Animals; Ascorbic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Fentanyl; Glutathione; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase Inhibitors; Male; Neprilysin; Oligopeptides; Oxidation-Reduction; Ozone; Pyrilamine; Substance P; Vagus Nerve	1992
Effect of interleukin-1 receptor antagonist on antigen-induced pulmonary responses in guinea pigs. European journal of pharmacology, 1992, Mar-31, Volume: 213, Issue:3 Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Guinea Pigs; Humans; Leukocyte Count; Lymphocytes; Male; Neutrophils; Pneumonia; Receptors, Immunologic; Receptors, Interleukin-1; Sensitivity and Specificity; Substance P; Time Factors	1992
O3-induced airway hyperresponsiveness to noncholinergic system and other stimuli. Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:1 Topics: Animals; Autonomic Nervous System; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Ovalbumin; Ozone; Substance P; Trachea; Vagus Nerve	1992
[Asthma due to airway inflammation]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jun-10, Volume: 81, Issue:6 Topics: Airway Resistance; Animals; Asthma; Bradykinin; Bronchi; Bronchial Hyperreactivity; Bronchitis; Cytokines; Humans; Leukocytes; Substance P	1992
[Cough as a side effect of angiotensin-converting enzyme inhibitors]. Nederlands tijdschrift voor geneeskunde, 1992, Sep-19, Volume: 136, Issue:38 Topics: Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bronchial Hyperreactivity; Cough; Dinoprostone; Humans; Substance P	1992