substance p has been researched along with Breast Neoplasms in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 15 (48.39) | 24.3611 |
| 2020's | 6 (19.35) | 2.80 |
| Authors | Studies |
|---|---|
| Alwazzan, A; Gilani, SA; Hasan, S; Hassan, A; Javaid, S; Khalid, S; Mehboob, R; Munoz, M; Tanvir, I; Waseem, H | 1 |
| Al-Keilani, MS; Alqudah, MA; Bdeir, R; Elstaty, RI | 1 |
| Barr, J; Bell, M; Drapkin, R; Eichwald, T; Fettig, RR; Hooper, JE; Jung, E; Kovács, A; Lucido, CT; Muirhead, DM; Omran, DK; Reavis, H; Restaino, AC; Schwartz, LE; Spanos, WC; Talbot, S; Vermeer, DW; Vermeer, PD; Vermeer, SJ; Walz, A; Williamson, CS | 1 |
| Assaran Darban, R; Hashemy, SI; Jafarinezhad, S; Javid, H | 1 |
| Bergmann, A; Grill, S; Hamann, M; Hartmann, O; Kiechle, M; Pölcher, M; Struck, J | 1 |
| Alaei, A; Ebrahimi, S; Hashemy, SI; Javid, H | 1 |
| Al-Keilani, MS; Alkhateeb, AM; Alqudah, MA; Elstaty, RI | 1 |
| Erin, N; Nizam, E | 1 |
| Dong, D; Ji, W; Niu, R; Wang, L; Wang, Z; Yu, M; Zhang, F; Zhang, L; Zhou, Y | 1 |
| Asadi, M; Boroumand, N; Davoodian, M; Hashemy, SI; Jafarian, AH; Mehrabi Bahar, M | 1 |
| Chen, X; Xiong, T; Yang, J; Yao, Z; Yu, M; Zhang, Y; Zhao, L; Zhou, Y | 1 |
| Avraham, HK; Avraham, S; Fu, Y; Jiang, S; Rodriguez, PL | 1 |
| Almendro, V; Ametller, E; Costamagna, D; Engel, P; Fernandez, PL; Fernandez-Nogueira, P; Fuster, G; Garcia-Recio, S; Gascón, P; Gonzalez-Farre, X; Mancino, M; Mayordomo, C; Park, SY; Pastor-Arroyo, EM; Russnes, HG | 1 |
| Liang, R; Ma, Y; Ni, J; Song, J; Wang, R; Wei, X; Zhang, L; Zhang, W; Zhang, Y | 1 |
| Almendro, V; Carranza, A; Coveñas, R; Garcia-Recio, S; González-Ortega, A; Muñoz, M; Salinas-Martín, MV | 1 |
| Demir, N; Erin, N; Kale, Ş; Köksoy, S; Korcum, AF; Tanrıöver, G | 1 |
| Almendro, V; Garcia-Recio, S; Gascón, P; Marín-Aguilera, M; Pastor-Arroyo, EM | 1 |
| Dalaklioglu, S; Erin, N | 1 |
| Greco, SJ; Patel, PS; Rameshwar, P; Reddy, BY; Trzaska, KA | 1 |
| Casinello, F; Coveñas, R; Muñoz, M; Rosso, M | 1 |
| Almendro, V; Ametller, E; Casas, I; Fernández-Nogueira, P; García-Recio, S; Gascón, P; Mayordomo, C; Pastor-Arroyo, EM; Vinyals, L | 1 |
| Demir, N; Duymuş, O; Erin, N; Oztürk, S | 1 |
| Drell, TL; Entschladen, F; Joseph, J; Lang, K; Niggemann, B; Zaenker, KS | 1 |
| Drell, TL; Entschladen, F; Kaltschmidt, C; Lang, K; Lindecke, A; Niggemann, B; Zaenker, KS | 1 |
| Benzo, A; Bigioni, M; Goso, C; Irrissuto, C; Maggi, CA | 1 |
| Horiba, K; Ishikawa, N; Kanazawa, Y; Koizumi, M; Kudoh, H; Ohkawa, K; Seya, T; Shirakawa, T; Tajiri, T; Tanaka, N; Yamada, T; Yokoi, K; Yoshioka, M | 1 |
| Aalto, Y; Bergh, J; Forsgren, S; Franzén, L; Henriksson, R; Kjörell, U | 1 |
| Gascón, P; Hameed, M; Joshi, DD; Maloof, PB; Mosenthal, A; Qian, J; Rameshwar, P; Singh, D | 1 |
| Patel, KV; Schrey, MP | 1 |
| Ausseil, M; Barneon, G; Bousquet, J; Godard, P; Hejjaoui, A; Joyeux, H; Michel, FB; Nardoux, J; Pujol, JL | 1 |
| Ahlman, H; Dahlström, A; Grönstad, K; Larsson, I; Tisell, LE | 1 |
1 review(s) available for substance p and Breast Neoplasms
| Article | Year |
|---|---|
New insight into the role of substance P/neurokinin-1 receptor system in breast cancer progression and its crosstalk with microRNAs.
Topics: Breast Neoplasms; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Phosphorylation; Receptors, Neurokinin-1; Signal Transduction; Substance P | 2020 |
1 trial(s) available for substance p and Breast Neoplasms
| Article | Year |
|---|---|
Skin test reactivity in patients suffering from lung and breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Codeine; Female; Histamine; Humans; Lung Neoplasms; Mast Cells; Middle Aged; Skin Tests; Substance P | 1991 |
29 other study(ies) available for substance p and Breast Neoplasms
| Article | Year |
|---|---|
Prognostic Significance of Substance P/Neurokinin 1 Receptor and Its Association with Hormonal Receptors in Breast Carcinoma.
Topics: Adult; Aged; Animals; Breast Neoplasms; Estrogen Receptor alpha; Female; Humans; Ki-67 Antigen; Middle Aged; Prognosis; Receptor, ErbB-2; Receptors, Neurokinin-1; Receptors, Progesterone; Substance P | 2021 |
Expression of substance P, neurokinin 1 receptor, Ki-67 and pyruvate kinase M2 in hormone receptor negative breast cancer and evaluation of impact on overall survival.
Topics: Breast Neoplasms; Female; Hormones; Humans; Ki-67 Antigen; Pyruvate Kinase; Receptors, Neurokinin-1; Substance P; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2023 |
Functional neuronal circuits promote disease progression in cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Human Papillomavirus Viruses; Humans; Mice; Mice, Inbred C57BL; Neurons; Ovarian Neoplasms; Ovary; Specific Pathogen-Free Organisms; Squamous Cell Carcinoma of Head and Neck; Substance P; Survival Analysis | 2023 |
The SP/NK1R system promotes the proliferation of breast cancer cells through NF-κB-mediated inflammatory responses.
Topics: Aprepitant; Breast Neoplasms; Cell Proliferation; Cytokines; Female; Humans; Interleukin-6; NF-kappa B; Reactive Oxygen Species; Receptors, Neurokinin-1; Substance P; Tumor Suppressor Protein p53 | 2023 |
Detection of early breast cancer beyond mammographic screening: a promising biomarker panel.
Topics: Adult; Aged; Area Under Curve; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Early Detection of Cancer; Enkephalins; Female; Human Growth Hormone; Humans; Logistic Models; Mammography; Middle Aged; Mucin-1; Neoplasm Grading; Neoplasm Staging; Protein Precursors; ROC Curve; Substance P | 2019 |
Immunohistochemical expression of substance P in breast cancer and its association with prognostic parameters and Ki-67 index.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Lymphatic Metastasis; Middle Aged; Neoplasm Grading; Neoplasm Staging; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Substance P | 2021 |
Differential consequences of neurokinin receptor 1 and 2 antagonists in metastatic breast carcinoma cells; Effects independent of Substance P.
Topics: Animals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL2; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Isoindoles; Mice; Neoplasm Metastasis; Neurokinin-1 Receptor Antagonists; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 2018 |
MiR-34b/c-5p and the neurokinin-1 receptor regulate breast cancer cell proliferation and apoptosis.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HEK293 Cells; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Receptors, Neurokinin-1; RNA Interference; RNA, Small Interfering; Substance P; Xenograft Model Antitumor Assays | 2019 |
Evaluation of serum level of substance P and tissue distribution of NK-1 receptor in breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Case-Control Studies; Female; Humans; Middle Aged; Receptors, Neurokinin-1; Staining and Labeling; Substance P; Tissue Distribution | 2019 |
Roles of full-length and truncated neurokinin-1 receptors on tumor progression and distant metastasis in human breast cancer.
Topics: Aniline Compounds; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; Humans; Inositol 1,4,5-Trisphosphate; Mammary Glands, Human; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurokinin-1 Receptor Antagonists; Phosphorylation; Receptors, Neurokinin-1; Reference Values; Substance P; Triazoles | 2013 |
The proinflammatory peptide substance P promotes blood-brain barrier breaching by breast cancer cells through changes in microvascular endothelial cell tight junctions.
Topics: Animals; Blood-Brain Barrier; Breast Neoplasms; Cell Adhesion; Cell Movement; Cytoskeleton; Endothelial Cells; Female; Humans; Mice; Microvessels; Permeability; Substance P; Tight Junctions; Tumor Necrosis Factor-alpha | 2014 |
Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer.
Topics: Apoptosis; Autocrine Communication; Blotting, Western; Breast Neoplasms; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; ErbB Receptors; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurotransmitter Agents; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Receptors, Neurokinin-1; RNA, Small Interfering; Signal Transduction; Substance P; Tumor Cells, Cultured | 2013 |
Functional properties of a novel hybrid antimicrobial peptide NS: potent antitumor activity and efficient plasmid delivery.
Topics: Acylation; Animals; Antimicrobial Cationic Peptides; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Chlorocebus aethiops; COS Cells; DNA Replication; Female; Genetic Therapy; Glioblastoma; Humans; Plasmids; Protein Sorting Signals; Protein Transport; Recombinant Proteins; Substance P; Transfection; Uterine Cervical Neoplasms | 2014 |
The neurokinin-1 receptor antagonist aprepitant is a promising candidate for the treatment of breast cancer.
Topics: Antineoplastic Agents; Aprepitant; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; MCF-7 Cells; Morpholines; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Substance P; Tryptophan | 2014 |
Activation of neuroimmune pathways increases therapeutic effects of radiotherapy on poorly differentiated breast carcinoma.
Topics: Animals; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Docetaxel; Female; Mice; Mice, Inbred BALB C; Substance P; Taxoids; Treatment Outcome | 2015 |
The Transmodulation of HER2 and EGFR by Substance P in Breast Cancer Cells Requires c-Src and Metalloproteinase Activation.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; CSK Tyrosine-Protein Kinase; Enzyme Activation; ErbB Receptors; Female; Gene Expression; Humans; Metalloproteases; Neurokinin-1 Receptor Antagonists; Phosphorylation; Protein Binding; Receptor, ErbB-2; Receptors, Neurokinin-1; src-Family Kinases; Substance P; Trans-Activators | 2015 |
Substance P Prevents Vascular Endothelial Dysfunction in Metastatic Breast Carcinoma.
Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Endothelium, Vascular; Female; Mice; Mice, Inbred BALB C; Nitroprusside; Oxidative Stress; Phenylephrine; Potassium Chloride; Substance P | 2016 |
RE-1-silencing transcription factor shows tumor-suppressor functions and negatively regulates the oncogenic TAC1 in breast cancer cells.
Topics: Binding Sites; Breast Neoplasms; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Repressor Proteins; Severity of Illness Index; Substance P; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2009 |
Paravertebral anesthesia: how substance P and the NK-1 receptor could be involved in regional block and breast cancer recurrence.
Topics: Anesthesia, Spinal; Breast Neoplasms; Female; Humans; Mastectomy; Neoplasm Recurrence, Local; Receptors, Neurokinin-1; Substance P; Treatment Outcome | 2010 |
Targeting of substance P induces cancer cell death and decreases the steady state of EGFR and Her2.
Topics: Antibodies; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Lapatinib; Ligands; Male; Neoplasms; Neurokinin-1 Receptor Antagonists; Piperidines; Prostatic Neoplasms; Quinazolines; Receptor, ErbB-2; Receptors, Neurokinin-1; Signal Transduction; Substance P; Trastuzumab | 2012 |
Activation of vagus nerve by semapimod alters substance P levels and decreases breast cancer metastasis.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Female; Hydrazones; Liver Neoplasms, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neprilysin; Sensory Receptor Cells; Substance P; Vagotomy; Vagus Nerve | 2012 |
Effects of neurotransmitters on the chemokinesis and chemotaxis of MDA-MB-468 human breast carcinoma cells.
Topics: Antineoplastic Agents; Bombesin; Breast Neoplasms; Cell Migration Inhibition; Chemotaxis; Dopamine; Enkephalin, Methionine; Female; Flow Cytometry; gamma-Aminobutyric Acid; Humans; Microscopy, Video; Neurotransmitter Agents; Norepinephrine; Signal Transduction; Substance P; Tumor Cells, Cultured | 2003 |
Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs.
Topics: Breast Neoplasms; Carcinoma; Cell Movement; Collagen; Cyclic AMP Response Element-Binding Protein; Dopamine; Dopamine Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Image Processing, Computer-Assisted; Male; Microscopy, Video; Neoplasm Metastasis; Norepinephrine; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Signal Transduction; Substance P; Up-Regulation | 2004 |
Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cyclohexylamines; Female; Humans; Indoles; Mice; Mice, Nude; Molecular Structure; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Receptors, Neurokinin-1; Receptors, Neurokinin-2; RNA, Messenger; Substance P; Xenograft Model Antitumor Assays | 2005 |
[Substance P and anticancer drug-induced emesis].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Digestive System Neoplasms; Female; Humans; Male; Middle Aged; Nausea; Receptors, Neurokinin-1; Serotonin 5-HT3 Receptor Antagonists; Substance P; Vomiting, Anticipatory | 2007 |
Enhanced expression of neuropeptides in human breast cancer cell lines following irradiation.
Topics: Antibiotics, Antineoplastic; Bombesin; Breast Neoplasms; Cell Division; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Female; Gastrin-Releasing Peptide; Humans; Immunohistochemistry; Neuropeptides; Radioimmunoassay; Substance P; Tumor Cells, Cultured | 1998 |
Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis.
Topics: Benzamides; Biphenyl Compounds; Bone Marrow Cells; Bone Marrow Neoplasms; Breast Neoplasms; Cell Division; Female; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Neurokinin-1 Receptor Antagonists; Piperidines; Protein Precursors; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Tachykinins; Tumor Cells, Cultured | 2000 |
Modulation of inositol lipid hydrolysis in human breast cancer cells by two classes of bombesin antagonist.
Topics: Binding Sites; Bombesin; Breast Neoplasms; Female; Gastrin-Releasing Peptide; Humans; Hydrolysis; Inositol Phosphates; Peptides; Receptors, Bombesin; Receptors, Neurotransmitter; Signal Transduction; Substance P; Tumor Cells, Cultured | 1991 |
A case of midgut carcinoid with breast metastasis and cellular localization of serotonin and substance P.
Topics: Aged; Breast; Breast Neoplasms; Carcinoid Tumor; Female; Fluorescent Antibody Technique; Humans; Ileal Neoplasms; Liver; Liver Neoplasms; Malignant Carcinoid Syndrome; Serotonin; Substance P | 1986 |