substance p has been researched along with Bladder Pain Syndrome in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 9 (56.25) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Hiramoto, S; Irie, Y; Ishikura, H; Kawabata, A; Maeda, M; Nishibori, M; Sekiguchi, F; Tsubota, M; Wake, H | 1 |
| Chen, I; Chen, MY; Lee, CL; Lloyd, LK; Lo, TS; Tseng, LH | 1 |
| Burkhard, FC; Draeger, A; Kessler, TM; Kuhn, A; Monastyrskaya, K; Sanchez Freire, V | 1 |
| Birder, LA; Buffington, CA; Chib, MK; Hanna-Mitchell, AT; Roppolo, JR; Wolf-Johnston, AS | 1 |
| Guo, JX; Lu, GS; Song, B; Zhang, QH; Zhou, ZS | 1 |
| Bonney, I; Carr, DB; Marchand, JE; Sant, GR; Sukiennik, A; Wurm, H | 1 |
| Gupta, J; Hayashi, F; Hayashi, M; Iino, T; Nakae, K; Yamamoto, N; Yoshikawa, S | 1 |
| Gutkin, DW; Pezzone, MA; Ustinova, EE | 1 |
| Boucher, W; Pang, X; Sant, GR; Theoharides, TC; Triadafilopoulos, G | 1 |
| Ruggieri, MR | 1 |
| Buffington, CA; Wolfe, SA | 1 |
| Gerard, C; Gerard, NP; Hammond, TG; Lu, B; Nguyen, NB; Saban, MR; Saban, R | 1 |
| Boucher, W; Chiang, G; Green, M; Jeudy, S; Letourneau, R; Patra, P; Sant, GR; Theoharides, TC | 1 |
| Campbell, DJ; Clements, JA; Dwyer, PL; Rosamilia, A; Tenis, N | 1 |
| Bouchelouche, K; Bouchelouche, P; Hald, T; Horn, T; Larsen, S; Nordling, J | 1 |
| Brettschneider, N; Chiu, PY; Eisenberg, E; Kushner, L; Lipstein, A; Moldwin, R; Rofeim, O | 1 |
1 trial(s) available for substance p and Bladder Pain Syndrome
| Article | Year |
|---|---|
The effect of short-term epidural local anesthetic blockade on urinary levels of substance P in interstitial cystitis.
Topics: Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Cystitis, Interstitial; Humans; Pain; Pain Measurement; Radioimmunoassay; Substance P | 2004 |
15 other study(ies) available for substance p and Bladder Pain Syndrome
| Article | Year |
|---|---|
HMGB1 and its membrane receptors as therapeutic targets in an intravesical substance P-induced bladder pain syndrome mouse model.
Topics: Animals; Antibodies, Neutralizing; Cystitis, Interstitial; Disease Models, Animal; Female; HMGB1 Protein; Humans; Male; Mice, Inbred Strains; Molecular Targeted Therapy; Receptor for Advanced Glycation End Products; Receptors, CXCR4; Receptors, Cytoplasmic and Nuclear; Substance P; Thrombomodulin | 2020 |
Genome-based expression profiles as a single standardized microarray platform for the diagnosis of experimental interstitial cystitis: an array of 75 genes model.
Topics: Animals; Cluster Analysis; Cystitis, Interstitial; Ephrins; Escherichia coli; Gene Expression Profiling; Lipopolysaccharides; Lymphocyte Activation; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Oligonucleotide Array Sequence Analysis; Ovalbumin; PAX2 Transcription Factor; Semaphorins; Substance P; Transcriptome; Up-Regulation; Wnt Signaling Pathway | 2009 |
MicroRNAs may mediate the down-regulation of neurokinin-1 receptor in chronic bladder pain syndrome.
Topics: Adult; Aged; Base Sequence; Biopsy; Cells, Cultured; Cystitis, Interstitial; Databases, Nucleic Acid; Down-Regulation; Epithelium; Female; Gene Expression Profiling; Humans; Inflammation; Male; MicroRNAs; Middle Aged; Molecular Sequence Data; Myocytes, Smooth Muscle; Permeability; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Syndrome; Urothelium; Young Adult | 2010 |
Beyond neurons: Involvement of urothelial and glial cells in bladder function.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Astrocytes; Cat Diseases; Cats; Cystitis, Interstitial; Enzyme Activation; Estradiol; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Intermediate Filament Proteins; Male; Mechanotransduction, Cellular; Nerve Growth Factor; Nerve Tissue Proteins; Nestin; p38 Mitogen-Activated Protein Kinases; Rats; Sensation; Substance P; Urinary Bladder; Urothelium | 2010 |
Melatonin improves bladder symptoms and may ameliorate bladder damage via increasing HO-1 in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Proliferation; Cystitis, Interstitial; Female; Heme Oxygenase-1; Inflammation; Mast Cells; Melatonin; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; Substance P; Urinary Bladder | 2013 |
Functional role of prostacyclin receptor in rat dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Capsaicin; Cells, Cultured; Cyclic AMP; Cystitis, Interstitial; Disease Models, Animal; Female; Ganglia, Spinal; Iloprost; Inflammation Mediators; Membrane Potentials; Neurons, Afferent; Nociceptors; Pain; Potassium Chloride; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Substance P; Vasodilator Agents | 2005 |
Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Bradykinin; Capsaicin; Chronic Disease; Colitis; Cystitis, Interstitial; Female; Mast Cells; Nerve Endings; Nerve Fibers, Unmyelinated; Neurons, Afferent; Neuropeptides; Pelvis; Physical Stimulation; Rats; Rats, Sprague-Dawley; Substance P; Trinitrobenzenesulfonic Acid; Urethane; Urinary Bladder | 2007 |
Mast cell and substance P-positive nerve involvement in a patient with both irritable bowel syndrome and interstitial cystitis.
Topics: Chymases; Colon; Colonic Diseases, Functional; Cystitis, Interstitial; Female; Histamine; Humans; Mast Cells; Methylhistamines; Middle Aged; Nerve Fibers; Serine Endopeptidases; Substance P; Tryptases; Urinary Bladder | 1996 |
Neurokinin receptors in feline interstitial cystitis.
Topics: Animals; Cat Diseases; Cats; Cystitis, Interstitial; Disease Models, Animal; Iodine Radioisotopes; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Pain; Radiopharmaceuticals; Receptors, Neurokinin-1; Substance P; Tritium | 1998 |
High affinity binding sites for [3H]substance P in urinary bladders of cats with interstitial cystitis.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Blood Vessels; Brain; Cats; Cystitis, Interstitial; Female; Iodine Radioisotopes; Male; Neurokinin A; Neurokinin B; Pain; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Substrate Specificity; Tritium; Up-Regulation; Urinary Bladder | 1998 |
Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis.
Topics: Animals; Cell Degranulation; Cystitis, Interstitial; Dinitrobenzenes; Dinitrophenols; Female; Hypersensitivity, Immediate; Immunization; Mast Cells; Mice; Mice, Knockout; Ovalbumin; Receptors, Neurokinin-1; Substance P; Urinary Bladder | 2000 |
Pentosanpolysulfate inhibits mast cell histamine secretion and intracellular calcium ion levels: an alternative explanation of its beneficial effect in interstitial cystitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Chondroitin Sulfates; Cromolyn Sodium; Cystitis, Interstitial; Dose-Response Relationship, Drug; Histamine Release; Histocytochemistry; Immunoglobulin E; Male; Mast Cells; Microscopy, Confocal; Microscopy, Electron; p-Methoxy-N-methylphenethylamine; Pentosan Sulfuric Polyester; Peritoneum; Rats; Rats, Sprague-Dawley; Substance P; Urinary Bladder | 2000 |
Urinary levels of substance P and its metabolites are not increased in interstitial cystitis.
Topics: Chromatography, High Pressure Liquid; Cystitis, Interstitial; Female; Humans; Substance P | 2001 |
Calcium signaling in cultured human detrusor smooth muscle cells from patients with interstitial cystitis.
Topics: Calcium; Cell Division; Cystitis, Interstitial; Female; Histamine; Humans; Leukotriene D4; Muscle, Smooth; Substance P; Urinary Bladder | 2001 |
Urinary substance P concentration correlates with urinary frequency and urgency in interstitial cystitis patients treated with intravesical dimethyl sulfoxide and not intravesical anesthetic cocktail.
Topics: Anesthetics; Biomarkers; Cystitis, Interstitial; Drug Combinations; Female; Humans; Substance P; Urination Disorders | 2001 |