substance p has been researched along with Asthma, Bronchial in 113 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 14 (12.39) | 18.7374 |
1990's | 48 (42.48) | 18.2507 |
2000's | 26 (23.01) | 29.6817 |
2010's | 21 (18.58) | 24.3611 |
2020's | 4 (3.54) | 2.80 |
Authors | Studies |
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Guan, Y; Liu, C; Ma, Y; Tang, Y; Xi, G; Xu, Y; Zhang, J | 1 |
Li, M; Xu, WT; Zhong, X | 1 |
Chen, D; Chen, L; Han, P; He, S; Liu, J; Wang, W; Yang, R; Zhang, H | 1 |
Chen, Y; Gao, W; Gao, Y; Lu, W | 1 |
Ali, H | 1 |
Blum, ED; Costello, RW; Drake, MG; Fryer, AD; Jacoby, DB; Lebold, KM; Lee, JJ; Nie, Z; Scott, GD | 1 |
Guo, SC; Wang, QY; Xu, CW; Zheng, ZW | 1 |
Chen, R; Lai, K; Li, J; Li, L; Liu, X; Ma, P; Wu, Y; Yang, X; Yao, H; Ye, X; You, H; Yuan, Y | 1 |
Carlsten, CR; MacNutt, MJ; Sava, F | 1 |
Tang, HQ; Wang, BJ; Yang, Y; Ye, JH; Zheng, XL; Zheng, XR | 1 |
Bhatia, M; Sun, J | 1 |
Hou, W; Liu, H; Yang, X | 1 |
Iwabuchi, S; Kaneumi, S; Kishikawa, T; Kita, T; Kitamura, H; Kobayashi, H; Masuko, K; Ohno, Y; Ohtake, J; Shinohara, T; Sumida, K; Takemura, T; Tanaka, S; Tanino, M; Tanino, Y; Terada, S | 1 |
Jiao, L; Xiong, J; Zhang, W | 1 |
Abou Alaiwa, M; Adam, RJ; Jaffer, O; Meyerholz, DK; Michalski, AS; Powers, LS; Price, MP; Reznikov, LR; Stoltz, DA; Welsh, MJ | 1 |
Fan, X; Liu, H; Wang, N; Yu, J; Zhang, Y | 1 |
Bullens, DM; Cadot, P; Callebaut, I; Ceuppens, JL; Hellings, PW; Hens, G; Meyts, I; Nemery, B; Raap, U; Vanaudenaerde, BM; Vanoirbeek, J; Verbinnen, B | 1 |
Dong, R; Lu, BS; Zhang, M | 1 |
Fang, LP; Li, SJ; Li, ZC; Lin, HJ; Qi, HW; Xie, BM | 1 |
Liu, B; Lü, H; Qiu, Z; Xu, S; Yu, L; Zhao, T | 1 |
Ewert, R; Felix, SB; Gläser, S; Gustavus, B; Koch, B; Kunkel, G; Noga, O; Schäper, C | 1 |
Couto, N; Moreira, A; Ramalho, R; Soares, R | 1 |
Aoyama, N; Chin, K; Ito, I; Jinnai, M; Matsumoto, H; Matsuoka, H; Mishima, M; Nakaji, H; Niimi, A; Oguma, T; Otsuka, K; Sasaki, K; Takeda, T; Yamaguchi, M | 1 |
Bermudez, J; Espina, LM; Giuffrida, M; Gotera, J; Maldonado, M; Mavarez, A; Mosquera, J; Pons, H; Valero, N | 1 |
Almeida, J; Beltrão, M; Costa, R; Delgado, L; Guardão, L; Guimarães, JT; Moreira, A; Palmares, C; Pirraco, A; Ramalho, R; Soares, R; Sokhatska, O | 2 |
Braun, A; Rochlitzer, S; Spies, E; Veres, TZ; Voedisch, S | 1 |
Chien, CS; Hsiao, LD; Lin, CC; Luo, SF; Wang, CC; Yang, CM | 1 |
Braun, A; Dinh, QT; Fischer, A; Groneberg, DA; Kerzel, S; Nockher, WA; Päth, G; Quarcoo, D; Raap, U; Renz, H | 1 |
Adkins, B; Auais, A; Napchan, G; Piedimonte, G | 1 |
Piedimonte, G | 1 |
Duffy, RA | 1 |
Dziedziczko, A; Pałgan, K | 1 |
Morimoto, K; Mukaiyama, O; Nosaka, E; Takahashi, S; Yamashita, M | 2 |
De Swert, KO; Joos, GF; Pauwels, RA; Tournoy, KG | 1 |
Feng, JT; Hu, CP | 1 |
Dong, XF; Luo, XR; Ye, XQ; Zhang, D | 1 |
Bergren, DR | 1 |
De Swert, KO; Joos, GF | 1 |
Guan, C; Luo, Z; Qi, M; Qin, X; Wu, H; Xiang, Y; Zhang, C | 1 |
Arck, PC; Dinh, T; Joachim, RA; Klapp, BF; Quarcoo, D; Sagach, V | 1 |
Braun, A; de Vries, A; Dessing, MC; Engels, F; Fischer, A; Groneberg, DA; Henricks, PA; Leusink-Muis, T; McGregor, GP; Nijkamp, FP | 1 |
Feng, JT; Hu, CP; Lin, MJ; Luo, BL; Tang, YL; Zhu, JQ | 1 |
Rosenkranz, MA | 1 |
Eiubova, AA; Sultanova, NG | 1 |
Egan, RW; Fernandez, X; Jones, H; Kreutner, W; Kung, T; Mauser, PJ; Pitman, A; Watnick, AS; Witt, A; Zurcher, J | 1 |
Ichinose, M; Igarashi, A; Inoue, H; Miura, M; Nakajima, N; Shirato, K; Takahashi, T; Takishima, T; Yamauchi, H | 1 |
Li, PS; Liu, A; Zhang, ZJ | 1 |
Arakawa, H; Kuroume, T; Morikawa, A; Tokuyama, K; Yokoyama, T | 1 |
Cheung, D; den Hartigh, J; Dijkman, JH; Sterk, PJ; van der Veen, H | 1 |
Bai, TR; Drazen, JM; Hall, AE; Lilly, CM; Shore, SA | 1 |
Hirayama, Y; Ichinose, M; Miura, M; Nakajima, N; Shirato, K; Tomaki, M; Yamauchi, H | 1 |
Arakawa, H; Maeda, S; Morikawa, A; Tokuyama, K | 1 |
Baumgarten, C; Furkert, J; Kunkel, G; Laake, E; Müller, S; Nieber, K; Rathsack, R | 1 |
Bordner, J; Bryce, DK; Drozda, SE; Jackson, ER; Longo, KP; Lowe, JA; McLean, S; Morrone, J; Snider, RM; Zorn, SH | 1 |
Abe, T; Ando, T; Fukuda, N; Ichimura, T; Kanno, N; Yanaihara, N; Yoshihara, S | 1 |
Nansel, D; Szlazak, M | 1 |
Burkholder, TP; Knippenberg, RW; Kudlacz, EM; Logan, DE; Poirot, M; Shatzer, SA; van Giersbergen, PL | 1 |
Cross, LJ; Ennis, M; Heaney, LG | 2 |
Carney, AS; Jones, NS | 1 |
Chung, KF | 1 |
Belvisi, M | 1 |
Fujimura, M; Ishiura, Y; Matsuda, T; Myou, S; Tsujiura, M | 1 |
Endoh, N; Ichinose, M; Ishikawa, J; Kageyama, N; Miura, M; Ohuchi, Y; Shirato, K; Tomaki, M | 1 |
Alger, LE; Carson, SS; Garland, A; Leff, AR; McAllister, K; Necheles, J; Neeley, SP; Solway, J; White, SR | 1 |
Akuta, K; Manabe, H; Ohmori, K; Okamura, K | 1 |
Bagarozzi, DA; Potempa, J; Travis, J | 1 |
Buchanan, KD; Cross, LJ; Ennis, M; Heaney, LG; McGarvey, LP; Shaw, C | 1 |
Bousquet, J; Chanez, P; Godard, P; Moradoghi-Hattvani, A; Polak, JM; Springall, D; Vignola, AM | 1 |
Fujiwara, H; Hirata, K; Kanazawa, H; Yoshikawa, J | 1 |
Ichinose, M | 1 |
Ennis, M; Forsythe, P; Heaney, LG; MacMahon, J; McGarvey, LP | 1 |
Joos, GF; Pauwels, RA | 1 |
Germonpré, PR; Joos, GF; Pauwels, RA | 1 |
Chu, HW; Kraft, M; Krause, JE; Martin, RJ; Rex, MD | 1 |
Mao, B; Sun, B; Wu, C | 1 |
Liu, L; Liu, Y; Ren, J; Wang, F; Wu, S; Yu, H | 1 |
Hiemstra, PS; Rabe, KF; Sterk, PJ; Van Rensen, EL | 1 |
Bousquet, J; Chanez, P; Godard, P; Lacoste, JY; Michel, FB | 1 |
Boomsma, JD; Said, SI | 1 |
Betts, WH; McLennan, G; Scicchitano, R; Wozniak, A | 1 |
Barnes, PJ; Chung, KF; Lecomte, JM; Nichol, GM; O'Connor, BJ | 1 |
Ezaki, M; Hashimoto, M; Hayashi, K; Imanaka, H; Kiyoto, S; Kohsaka, M; Nishikawa, M; Okuhara, M; Shigematsu, N; Yamashita, M | 1 |
Baumgarten, CR; Furkert, J; Kunkel, G; Nieber, K; Oehme, P; Rathsack, R | 1 |
Inoue, H | 1 |
Iwamoto, I; Kimura, A; Tanaka, M; Tomioka, H; Yoshida, S | 2 |
Chu, YH; Li, J | 1 |
Harris, KE; Patterson, R | 1 |
Ishihara, H; Masuda, T; Sasaki, H; Sasaki, T; Satoh, M; Shimura, S; Takishima, T | 1 |
Akimoto, K; Iikura, Y; Nakai, S; Shiraki, K | 1 |
Barnes, PJ | 5 |
Armour, CL; Black, JL; Johnson, PR | 1 |
Jarvis, D; Ollerenshaw, SL; Sullivan, CE; Woolcock, AJ | 1 |
Djukanovic, R; Holgate, ST; Howarth, PH; Polak, JM; Springall, DR; Wilson, JW | 1 |
Bousquet, J; Braquet, P; Chanez, P; Damon, M; Godard, P; Mencia Huerta, JM; Michel, FB; Rabier, M | 1 |
Levitt, RC | 1 |
Joos, G; Kips, J; Pauwels, R; Van der Straeten, M | 1 |
Joos, G; Pauwels, R; van der Straeten, M | 1 |
Becher, G; Engelmann, C; Liedtke, D; Nieber, K; Oehme, P; Schreiber, J; Slapke, J | 1 |
Crimi, N; Mistretta, A | 1 |
Crimi, N; Mistretta, A; Oliveri, R; Palermo, B; Palermo, F; Polosa, R; Vancheri, C | 2 |
Fu, JX | 1 |
Sekizawa, K | 1 |
Nieber, K; Oehme, P; Schreiber, J; Slapke, J | 1 |
Bousquet, J; Chanez, P; Crastes de Paulet, A; de Vos, C; Godard, P; Grenier, J; Michel, F; Michel, FB; Pujol, JL | 1 |
25 review(s) available for substance p and Asthma, Bronchial
Article | Year |
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Emerging Roles for MAS-Related G Protein-Coupled Receptor-X2 in Host Defense Peptide, Opioid, and Neuropeptide-Mediated Inflammatory Reactions.
Topics: Analgesics, Opioid; Animals; Antimicrobial Cationic Peptides; Asthma; Cathelicidins; Cell Transdifferentiation; Chymases; Humans; Immunity, Innate; Inflammation; Mast Cells; Nerve Tissue Proteins; Organ Specificity; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance P; Tryptases | 2017 |
Substance P at the neuro-immune crosstalk in the modulation of inflammation, asthma and antimicrobial host defense.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antimicrobial Cationic Peptides; Asthma; Drug Design; Host-Pathogen Interactions; Humans; Inflammation; Inflammation Mediators; Signal Transduction; Substance P | 2014 |
Tachykinin receptors antagonism for asthma: a systematic review.
Topics: Anti-Asthmatic Agents; Asthma; Humans; Neurokinin A; Neurokinin B; Receptors, Tachykinin; Substance P; Treatment Outcome | 2011 |
Contribution of neuroimmune mechanisms to airway inflammation and remodeling during and after respiratory syncytial virus infection.
Topics: Animals; Asthma; Capillary Permeability; Child; Child, Preschool; Disease Models, Animal; Humans; Infant; Infant, Newborn; Lung; Muscle, Smooth; Nerve Growth Factors; Neuronal Plasticity; Pneumonia; Rats; Receptors, Neurokinin-1; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Risk Factors; Substance P; T-Lymphocytes | 2003 |
Potential therapeutic targets for neurokinin-1 receptor antagonists.
Topics: Analgesics; Anti-Anxiety Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antiemetics; Antineoplastic Agents; Antitussive Agents; Anxiety; Asthma; Clinical Trials as Topic; Cough; Cystitis; Depression; Drug Design; Humans; Inflammation; Irritable Bowel Syndrome; Neoplasms; Neurokinin-1 Receptor Antagonists; Pain; Substance P; Vomiting | 2004 |
[Role of neurotrophin and neuropeptides in bronchial asthma].
Topics: Asthma; Calcitonin Gene-Related Peptide; Humans; Nerve Growth Factor; Neurokinin A; Neuropeptides; Substance P | 2004 |
Extending the understanding of sensory neuropeptides.
Topics: Animals; Asthma; Bronchoconstriction; Clinical Trials as Topic; Disease Models, Animal; Humans; Neurokinin A; Neurons, Afferent; Neurotransmitter Agents; Pulmonary Disease, Chronic Obstructive; Receptors, Tachykinin; Respiratory System; Respiratory System Agents; Substance P | 2006 |
Substance P at the nexus of mind and body in chronic inflammation and affective disorders.
Topics: Adrenal Medulla; Asthma; Chronic Disease; Humans; Hypothalamo-Hypophyseal System; Inflammation; Mood Disorders; Pituitary-Adrenal System; Psychophysiology; Substance P | 2007 |
Discovery of CP-96,345 and its characterization in disease models involving substance P.
Topics: Analgesics; Animals; Asthma; Binding, Competitive; Biphenyl Compounds; Disease Models, Animal; Inflammation; Pain; Receptors, Neurokinin-2; Substance P | 1993 |
Idiopathic rhinitis: idiopathic or not?
Topics: Air Pollution; Asthma; Chronic Disease; Eosinophilia; Eosinophils; Humans; Immunoglobulin E; Immunoglobulin G; Interleukin-3; Interleukin-4; Rhinitis; Substance P | 1996 |
Effects of nedocromil sodium on airway neurogenic mechanisms.
Topics: Animals; Asthma; Bronchoconstriction; Humans; Nedocromil; Substance P | 1996 |
Beta-blocker induced asthma: a role for sensory nerve hyperresponsiveness?
Topics: Adrenergic beta-Antagonists; Animals; Asthma; Bronchial Hyperreactivity; Guinea Pigs; Humans; Neurokinin A; Neurons, Afferent; Substance P | 1996 |
[Airway autonomic nervous system dysfunction and asthma].
Topics: Acetylcholine; Animals; Asthma; Autonomic Nervous System Diseases; Bradykinin; Bronchi; Cholinergic Fibers; Humans; Nitric Oxide; Substance P; Sympathetic Nervous System | 1999 |
Pro-inflammatory effects of substance P: new perspectives for the treatment of airway diseases?
Topics: Adjuvants, Immunologic; Animals; Asthma; Humans; Inflammation Mediators; Lung Diseases, Obstructive; Receptors, Tachykinin; Substance P; Tachykinins | 2000 |
Role of tachykinins in asthma.
Topics: Asthma; Humans; Lung; Neurogenic Inflammation; Neurokinin A; Neurons, Afferent; Receptors, Tachykinin; Substance P | 2000 |
[Mediators and neuromediators in asthma].
Topics: Asthma; Atrial Natriuretic Factor; Cytokines; Histamine; Humans; Leukotrienes; Parasympathetic Nervous System; Platelet Activating Factor; Prostaglandins; Substance P; Sympathetic Nervous System; Sympathomimetics; Vasoactive Intestinal Peptide | 1992 |
The role of neuropeptides in asthma.
Topics: Administration, Inhalation; Asthma; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Endothelins; Humans; Neuropeptides; Substance P; Vasoactive Intestinal Peptide | 1992 |
Neuropeptides and asthma.
Topics: Animals; Asthma; Axons; Bronchi; Calcitonin Gene-Related Peptide; Epithelium; Humans; Nervous System Physiological Phenomena; Neuropeptides; Reflex; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1991 |
Non-adrenergic non-cholinergic neural control of human airways.
Topics: Acetylcholine; Asthma; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Humans; Lung; Muscle, Smooth; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Peptide PHI; Peptides; Respiratory Physiological Phenomena; Respiratory System; Substance P; Vasoactive Intestinal Peptide | 1986 |
The respiratory effects of neuropeptides.
Topics: Airway Resistance; Animals; Asthma; Bronchi; Humans; Inflammation; Kinins; Lung; Nerve Tissue Proteins; Substance P; Vasoactive Intestinal Peptide; Vasodilation | 1986 |
Neuropeptides and airway smooth muscle.
Topics: Animals; Asthma; Calcitonin Gene-Related Peptide; Humans; Muscle, Smooth; Neuropeptides; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Respiratory Physiological Phenomena; Respiratory System; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1988 |
Neuropeptides in human airways.
Topics: Asthma; Humans; Neuropeptides; Respiratory System; Substance P; Vasoactive Intestinal Peptide | 1988 |
[Neuroautonomic mechanisms and neuropeptides in bronchial asthma].
Topics: Animals; Asthma; Autonomic Nervous System; Capsaicin; Humans; Neuropeptides; Substance P; Vasoactive Intestinal Peptide | 1988 |
[Nonadrenergic noncholinergic nervous system in the lung and bronchial asthma].
Topics: Animals; Asthma; Humans; Lung; Substance P; Vasoactive Intestinal Peptide | 1988 |
[The role of substance P in regulating bronchomotor tone and the pathogenesis of bronchial hyperreactivity].
Topics: Animals; Asthma; Bronchi; Bronchial Diseases; Bronchitis; Edema; Humans; Substance P; Vasodilation | 1989 |
12 trial(s) available for substance p and Asthma, Bronchial
Article | Year |
---|---|
[Effect of gamma-aminobutyric acid treatment on plasma substance P and calcitonin gene-related peptide levels in children with asthma].
Topics: Asthma; Calcitonin Gene-Related Peptide; Child; Child, Preschool; Female; gamma-Aminobutyric Acid; Humans; Male; Substance P | 2013 |
Nasal neurogenic inflammation markers increase after diesel exhaust inhalation in individuals with asthma.
Topics: Adult; Analysis of Variance; Asthma; Biomarkers; Calcitonin Gene-Related Peptide; Cross-Over Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inhalation; Male; Middle Aged; Nasal Cavity; Nasal Lavage Fluid; Neurogenic Inflammation; Substance P; Vehicle Emissions; Young Adult | 2013 |
Anti-inflammatory properties of montelukast, a leukotriene receptor antagonist in patients with asthma and nasal polyposis.
Topics: Acetates; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Asthma, Aspirin-Induced; Cell Count; Cyclopropanes; Cysteine; Eosinophils; Female; Humans; Leukotriene Antagonists; Leukotrienes; Male; Middle Aged; Nasal Lavage Fluid; Nasal Polyps; Neurokinin A; Quinolines; Substance P; Sulfides; Treatment Outcome | 2011 |
Effects of inhaled substance P on airway responsiveness to methacholine in asthmatic subjects in vivo.
Topics: Administration, Inhalation; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Substance P | 1994 |
Effect of procaterol, a beta 2-adrenoceptor agonist, on skin whealing response caused by inflammatory mediators in asthmatic children.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bradykinin; Child; Cross-Over Studies; Female; Histamine; Humans; Male; Platelet Activating Factor; Procaterol; Skin; Skin Tests; Substance P | 1995 |
Effect of azelastine on substance P content in bronchoalveolar and nasal lavage fluids of patients with allergic asthma.
Topics: Adolescent; Adult; Asthma; Bronchoalveolar Lavage Fluid; Exudates and Transudates; Female; Histamine H1 Antagonists; Humans; Male; Nasal Cavity; Phthalazines; Poaceae; Pollen; Rhinitis; Substance P; Therapeutic Irrigation | 1993 |
Histamine release from bronchoalveolar lavage cells from asthmatic subjects after allergen challenge and relationship to the late asthmatic response.
Topics: Adolescent; Adult; Allergens; Antibodies, Anti-Idiotypic; Asthma; Basophils; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Chymases; Concanavalin A; Female; Histamine Release; Humans; Inflammation Mediators; Leukocyte Count; Male; Mast Cells; Serine Endopeptidases; Substance P; Time Factors; Tryptases | 1998 |
Substance P and its receptor neurokinin 1 expression in asthmatic airways.
Topics: Adult; Anti-Bacterial Agents; Asthma; Biopsy; Bronchi; Epithelium; Female; Forced Expiratory Volume; Humans; Male; Mucus; Mycoplasma pneumoniae; Receptors, Neurokinin-1; Substance P | 2000 |
Assessment of microvascular leakage via sputum induction: the role of substance P and neurokinin A in patients with asthma.
Topics: Adult; Albumins; alpha-Macroglobulins; Asthma; Biomarkers; Capillary Permeability; Ceruloplasmin; Cross-Over Studies; Female; Fibrinogen; Humans; Male; Neurokinin A; Single-Blind Method; Sputum; Statistics, Nonparametric; Substance P | 2002 |
Effect of neutral endopeptidase inhibitor on airway function and bronchial responsiveness in asthmatic subjects.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Neprilysin; Skin; Substance P; Sulfites; Thiorphan | 1992 |
Effect of nedocromil on bronchospasm induced by inhalation of substance P in asthmatic subjects.
Topics: Adolescent; Adult; Aerosols; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Histamine; Humans; Male; Nedocromil; Quinolines; Substance P | 1988 |
Bronchospasm induced by inhalation of substance P: effect of sodium cromoglycate.
Topics: Administration, Inhalation; Adolescent; Adult; Animals; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Cromolyn Sodium; Female; Guinea Pigs; Humans; Male; Substance P | 1988 |
76 other study(ies) available for substance p and Asthma, Bronchial
Article | Year |
---|---|
Bioinformatic Analysis and Cellular Assays Identify Substance P Influencing Th17/Treg Differentiation via the MyD88 Pathway as a Potential Contributor to the Progression of Asthma and Allergic Rhinitis.
Topics: Asthma; Biomarkers; Blotting, Western; Cell Line; Cytokines; Disease Progression; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-17; Myeloid Differentiation Factor 88; Real-Time Polymerase Chain Reaction; Rhinitis, Allergic; RNA, Messenger; Signal Transduction; Substance P; T-Lymphocytes, Regulatory; Up-Regulation | 2022 |
Substance P promotes the progression of bronchial asthma through activating the PI3K/AKT/NF-κB pathway mediated cellular inflammation and pyroptotic cell death in bronchial epithelial cells.
Topics: Animals; Asthma; Carrier Proteins; Caspase 1; Epithelial Cells; Humans; Inflammasomes; Inflammation; Interleukin-18; Lactate Dehydrogenases; Leukocytes, Mononuclear; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyroptosis; Receptors, Neurokinin-1; Substance P | 2022 |
Upregulated expression of substance P and NK1R in blood monocytes and B cells of patients with allergic rhinitis and asthma.
Topics: Allergens; Animals; Asthma; Mice; Monocytes; Ovalbumin; Receptors, Neurokinin-1; Rhinitis, Allergic; Substance P | 2022 |
Influence of acupuncture on the expression of VIP, SP, NKA and NKB, cAMP/cGMP and HE content and treatment of bronchial asthma in rats.
Topics: Acupuncture Therapy; Animals; Asthma; Cyclic AMP; Cyclic GMP; Immunohistochemistry; Inflammation Mediators; Lung; Male; Neurokinin B; Rats; Rats, Wistar; Substance P; Vasoactive Intestinal Peptide | 2020 |
Eosinophils increase airway sensory nerve density in mice and in human asthma.
Topics: Adult; Aged; Animals; Asthma; Bronchoconstriction; Bronchodilator Agents; Eosinophils; Female; Humans; Lung; Male; Mice, Inbred C57BL; Middle Aged; Neurons; Quality of Life; Reflex; Respiratory Hypersensitivity; Substance P; Young Adult | 2018 |
Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice.
Topics: Acetanilides; Animals; Asthma; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Formaldehyde; Immunoglobulin E; Immunohistochemistry; Interleukin-1beta; Interleukin-4; Interleukin-6; Lung; Male; Mice; Mice, Inbred BALB C; Neuropeptides; Ovalbumin; Purines; Substance P; Transient Receptor Potential Channels | 2013 |
[Changes of CCK-8, CGRP, SP, and VIP in the colon and the lung tissue of allergic asthma model rats: an experimental observation].
Topics: Animals; Asthma; Calcitonin Gene-Related Peptide; Colon; Disease Models, Animal; Lung; Male; Rats; Rats, Wistar; Sincalide; Substance P; Vasoactive Intestinal Peptide | 2013 |
Correlation of c-fos protein expression with neuropeptide content in the lung of bronchial asthmatic rat.
Topics: Animals; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Male; Neuropeptides; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance P; Vasoactive Intestinal Peptide | 2014 |
Neuropeptide signaling through neurokinin-1 and neurokinin-2 receptors augments antigen presentation by human dendritic cells.
Topics: Alveolitis, Extrinsic Allergic; Antigen Presentation; Antigens, Surface; Asthma; Cell Differentiation; Cytokines; Dendritic Cells; Humans; Neurokinin A; Neurokinin-1 Receptor Antagonists; Poly I-C; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 2015 |
[Effects of Suspending Moxibustion at "Dazhui" (GV 14) on Neurogenic Inflammation in Asthma Rats].
Topics: Acupuncture Points; Animals; Asthma; Bronchoalveolar Lavage Fluid; Humans; Male; Moxibustion; Nerve Growth Factor; Neurogenic Inflammation; Neurokinin A; Rats; Rats, Sprague-Dawley; Substance P | 2015 |
Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice.
Topics: Acid Sensing Ion Channels; Animals; Asthma; Bronchoalveolar Lavage Fluid; Inflammation; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Respiratory Hypersensitivity; Respiratory System; Sensory Receptor Cells; Substance P; Vagus Nerve | 2016 |
Exacerbating effects of PM2.5 in OVA-sensitized and challenged mice and the expression of TRPA1 and TRPV1 proteins in lungs.
Topics: Airway Resistance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Eosinophils; Female; Interleukin-13; Mice; Mice, Inbred BALB C; Nerve Growth Factor; Ovalbumin; Particulate Matter; Prostaglandin D2; Respiratory Mechanics; Substance P; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2017 |
Selective nasal allergen provocation induces substance P-mediated bronchial hyperresponsiveness.
Topics: Administration, Inhalation; Allergens; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Immunization; Leukocyte Count; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Nasal Provocation Tests; Neurokinin-1 Receptor Antagonists; Ovalbumin; Receptors, Neurokinin-1; Substance P; Tryptophan; Up-Regulation | 2011 |
[The effect of central histamine H3 receptor on breathing activity of asthmatic guinea pigs].
Topics: Animals; Asthma; Brain; Guinea Pigs; Histamine Agonists; Histamine H3 Antagonists; Lateral Ventricles; Male; Methylhistamines; Muscle Contraction; Piperidines; Receptors, Histamine H3; Substance P; Trachea | 2006 |
[To explore the mechanisms of neurogenic inflammation and airway hyperresponsiveness of rat by inhaled sulfur].
Topics: Air Pollutants; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Male; Nerve Fibers; Neurogenic Inflammation; Random Allocation; Rats; Rats, Sprague-Dawley; Substance P; Sulfur Dioxide | 2009 |
Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux.
Topics: Adult; Aged; Asthma; Capsaicin; Chronic Disease; Cough; Cross-Sectional Studies; Female; Gastroesophageal Reflux; Histamine; Humans; Male; Middle Aged; Prospective Studies; Prostaglandin D2; Reflex; Respiratory Function Tests; Sputum; Substance P; Tryptases | 2011 |
Plasma substance P levels in patients with persistent cough.
Topics: Adult; Aged; Asthma; Cough; Enzyme-Linked Immunosorbent Assay; Female; Gastroesophageal Reflux; Humans; Male; Middle Aged; Respiratory Function Tests; Substance P | 2011 |
Respiratory syncytial virus infection increases regulated on activation normal T cell expressed and secreted and monocyte chemotactic protein 1 levels in serum of patients with asthma and in human monocyte cultures.
Topics: Adult; Aged; Asthma; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Monocytes; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Substance P; T-Lymphocytes; Up-Regulation | 2012 |
Neurogenic inflammation in allergen-challenged obese mice: A missing link in the obesity-asthma association?
Topics: Allergens; Animals; Asthma; Blood Glucose; Bronchoalveolar Lavage Fluid; Cell Count; Diet, High-Fat; Immunoglobulin E; Insulin; Lung; Mice; Mice, Inbred BALB C; Mice, Obese; Neurogenic Inflammation; Obesity; Ovalbumin; Substance P; Tachykinins | 2012 |
Neuropeptides control the dynamic behavior of airway mucosal dendritic cells.
Topics: Animals; Asthma; Bone Marrow Cells; Bronchi; CD11c Antigen; Dendritic Cells; Hypersensitivity; Immune System; Inflammation; Lung; Mice; Mice, Transgenic; Microscopy; Microscopy, Confocal; Mucous Membrane; Neurons; Neuropeptides; Phagocytosis; Substance P | 2012 |
Substance P antagonist improves both obesity and asthma in a mouse model.
Topics: Allergens; Animals; Asthma; Biomarkers; Bronchial Hyperreactivity; Bronchitis; Disease Models, Animal; Mice; Neurokinin-1 Receptor Antagonists; Obesity; Substance P | 2013 |
Substance P-induced activation of p42/44 mitogen-activated protein kinase associated with cell proliferation in human tracheal smooth muscle cells.
Topics: Asthma; Cell Division; Cells, Cultured; DNA; Genistein; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Myocytes, Smooth Muscle; Pertussis Toxin; Phosphorylation; Pneumonia; Protein Isoforms; Protein Kinase C; Sensory Receptor Cells; Substance P; Thymidine; Trachea; Type C Phospholipases | 2002 |
Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Immunohistochemistry; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factors; Neurons; Ovalbumin; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Respiratory System; Substance P | 2003 |
Immunomodulatory effects of sensory nerves during respiratory syncytial virus infection in rats.
Topics: Adjuvants, Immunologic; Animals; Asthma; Leukocyte Count; Lung; Lymphocyte Subsets; Male; Monocytes; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Piperidines; Pneumonia, Viral; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Specific Pathogen-Free Organisms; Substance P | 2003 |
Greater involvement of neurokinins found in Guinea pig models of severe asthma compared with mild asthma.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Animals; Asthma; Biomarkers; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Capsaicin; Disease Models, Animal; Eosinophils; Guinea Pigs; Lung; Male; Methacholine Chloride; Neprilysin; Neurokinin A; Respiratory Hypersensitivity; Severity of Illness Index; Substance P | 2004 |
The role of the tachykinin NK1 receptor in airway changes in a mouse model of allergic asthma.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophilia; Immunoglobulin E; Lung; Mice; Mice, Knockout; Ovalbumin; Receptors, Neurokinin-1; Substance P | 2004 |
Involvement of enhanced neurokinin NK3 receptor expression in the severe asthma guinea pig model.
Topics: Animals; Asthma; Benzamides; Binding, Competitive; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Lung; Male; Methacholine Chloride; Neurokinin B; Ovalbumin; Peptide Fragments; Piperidines; Receptors, Neurokinin-3; Substance P; Tritium | 2004 |
Dysfunction of releasing adrenaline in asthma by nerve growth factor.
Topics: Adrenal Medulla; Animals; Asthma; Epinephrine; Evidence-Based Medicine; Gene Expression Regulation; Humans; Models, Biological; Nerve Growth Factor; Substance P | 2005 |
[Determination of plasma and sputum substance P content in patients with chronic obstructive pulmonary disease or asthma].
Topics: Aged; Asthma; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Sputum; Substance P | 2005 |
Prostaglandin involvement in lung C-fiber activation by substance P in guinea pigs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Asthma; Blood Pressure; Bradykinin; Capsaicin; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Guinea Pigs; Heart Rate; Indomethacin; Lung; Nerve Fibers, Unmyelinated; Prostaglandins; Respiratory Hypersensitivity; Substance P | 2006 |
Upregulation of substance P receptor expression by calcitonin gene-related peptide, a possible cooperative action of two neuropeptides involved in airway inflammation.
Topics: Animals; Asthma; Blotting, Western; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Guinea Pigs; Humans; Inflammation; Lung; Ozone; Protein-Tyrosine Kinases; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Substance P; Up-Regulation | 2007 |
Upregulation of tumor necrosis factor-alpha by stress and substance p in a murine model of allergic airway inflammation.
Topics: Acoustic Stimulation; Animals; Asthma; CD3 Complex; Disease Models, Animal; Interferon-gamma; Interleukin-4; Lung; Lymph Nodes; Lymphocyte Count; Mice; Mice, Inbred BALB C; Neuroimmunomodulation; Sound; Stress, Physiological; Substance P; T-Lymphocytes; Tumor Necrosis Factor-alpha; Up-Regulation | 2006 |
Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbazoles; Disease Models, Animal; Enzyme Inhibitors; Female; Guinea Pigs; Immunohistochemistry; Indole Alkaloids; Lung; Male; Nerve Growth Factor; Neurons; Nodose Ganglion; Ovalbumin; Receptor, trkA; Signal Transduction; Substance P; Tyrphostins | 2006 |
[Experimental study on the mechanisms of regulating airway neurogenic inflammation in asthma by never growth factor and leukemia inhibitory factor].
Topics: Animals; Asthma; Disease Models, Animal; Ganglia, Spinal; Leukemia Inhibitory Factor; Lung; Male; Nerve Growth Factor; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P | 2006 |
[Neuroimmune regulation in children with bronchial asthma].
Topics: Adolescent; Asthma; Child; Child, Preschool; Female; Humans; Male; Neurokinin A; Substance P | 2008 |
Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma.
Topics: Animals; Antibodies, Monoclonal; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Eosinophils; Guinea Pigs; Immunization; Interleukin-5; Lung; Male; Ovalbumin; Substance P | 1993 |
Bradykinin-induced airway inflammation. Contribution of sensory neuropeptides differs according to airway site.
Topics: Animals; Asthma; Atropine; Bradykinin; Capillary Permeability; Dipeptides; Evans Blue; Guinea Pigs; Indoles; Indomethacin; Inflammation; Male; Neurons, Afferent; Premedication; Propranolol; Substance P; Tachykinins | 1994 |
[A clinical study on the effect of non-adrenergic non-cholinergic nerves in asthma].
Topics: Adult; Airway Resistance; Asthma; Bronchitis; Female; Humans; Lung; Male; Middle Aged; Substance P; Vasoactive Intestinal Peptide | 1993 |
Effects of cilostazol, a cyclic nucleotide phosphodiesterase III inhibitor, on substance P-induced airflow obstruction and airway microvascular leakage in guinea pigs.
Topics: Airway Obstruction; Airway Resistance; Animals; Asthma; Blood Pressure; Capillary Permeability; Cilostazol; Guinea Pigs; Injections, Intravenous; Lung; Male; Phosphodiesterase Inhibitors; Substance P; Tetrazoles | 1994 |
Neuropeptide content of lungs from asthmatic and nonasthmatic patients.
Topics: Adolescent; Adult; Aged; Asthma; Female; Humans; Immunohistochemistry; Lung; Male; Middle Aged; Substance P; Vasoactive Intestinal Peptide | 1995 |
Elevated substance P content in induced sputum from patients with asthma and patients with chronic bronchitis.
Topics: Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchitis; Chronic Disease; Eosinophils; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Radioimmunoassay; Saline Solution, Hypertonic; Sputum; Substance P; Vital Capacity | 1995 |
Involvement of substance P in the paroxysmal cough of pertussis.
Topics: Asthma; Child; Cough; Humans; Radioimmunoassay; Reference Values; Substance P; Whooping Cough | 1993 |
Enhanced phagocytic cell respiratory burst induced by spinal manipulation potential role of substance P (and) enhanced neutrophil respiratory burst as a biological marker for manipulation forces duration of the effect and association with substance P and
Topics: Asthma; Chiropractic; Humans; Manipulation, Orthopedic; Neutrophils; Respiratory Burst; Substance P; Tumor Necrosis Factor-alpha | 1993 |
In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist.
Topics: Amino Acid Sequence; Animals; Asthma; Bronchoconstriction; Capillary Permeability; Guinea Pigs; Humans; Inositol Phosphates; Male; Methacholine Chloride; Mice; Molecular Sequence Data; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Pyrrolidines; Rats; Receptors, Neurokinin-2; Respiration; Species Specificity; Substance P | 1996 |
Further characterisation of substance P induced histamine release from human bronchoalveolar lavage mast cells.
Topics: Anti-Bacterial Agents; Antimetabolites; Antimycin A; Asthma; Bronchoalveolar Lavage Fluid; Buffers; Calcium; Cough; Deoxyglucose; Glucose; Histamine Release; Humans; Mast Cells; Substance P | 1996 |
Role of sensory neuropeptides in post-allergic propranolol-induced bronchoconstriction in guinea pigs in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Dipeptides; Guinea Pigs; Indoles; Male; Neurokinin A; Peptides, Cyclic; Propranolol; Substance P | 1996 |
Role of endogenous nitric oxide in airway microvascular leakage induced by inflammatory mediators.
Topics: Aminoquinolines; Animals; Arginine; Asthma; Capillary Permeability; Coloring Agents; Dipeptides; Enzyme Inhibitors; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guanylate Cyclase; Guinea Pigs; Histamine; Indoles; Inflammation Mediators; Injections, Intravenous; Leukotriene D4; Lung; Male; Microcirculation; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Organometallic Compounds; Substance P | 1997 |
Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons.
Topics: Animals; Animals, Newborn; Asthma; Capsaicin; Cells, Cultured; Coculture Techniques; Cytochalasin B; Enzyme-Linked Immunosorbent Assay; Eosinophils; Ganglia, Spinal; Humans; Myelin Basic Protein; N-Formylmethionine Leucyl-Phenylalanine; Neurons; Platelet Activating Factor; Polylysine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic, Seasonal; Substance P; Tissue Extracts | 1997 |
KF19514, a phosphodieterase 4 and 1 inhibitor, inhibits PAF-induced lung inflammatory responses by inhaled administration in guinea pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Electric Stimulation; Eosinophils; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Naphthyridines; Neurokinin A; Neutrophils; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Activating Factor; Pyrrolidinones; Respiratory Therapy; Rolipram; Substance P | 1997 |
Purification and characterization of an arginine-specific peptidase from ragweed (Ambrosia artemisiifolia) pollen.
Topics: Amino Acid Sequence; Arginine; Asthma; Endopeptidases; Hypersensitivity; Molecular Sequence Data; Neuropeptides; Pollen; Protease Inhibitors; Serine Endopeptidases; Substance P; Substrate Specificity; Vasoactive Intestinal Peptide | 1998 |
Neurokinin A is the predominant tachykinin in human bronchoalveolar lavage fluid in normal and asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Calcitonin Gene-Related Peptide; Chromatography, High Pressure Liquid; Female; Humans; Male; Methacholine Chloride; Neurokinin A; Radioimmunoassay; Statistics, Nonparametric; Substance P | 1998 |
Bronchial mucosal immunoreactivity of sensory neuropeptides in severe airway diseases.
Topics: Administration, Oral; Adolescent; Adult; Aged; Asthma; Beclomethasone; Biomarkers; Biopsy; Bronchi; Bronchitis; Bronchoconstriction; Calcitonin Gene-Related Peptide; Capillary Permeability; Chronic Disease; Epithelium; Female; Fluorescent Antibody Technique, Direct; Glucocorticoids; Humans; Male; Middle Aged; Mucous Membrane; Muscle, Smooth; Nerve Tissue Proteins; Neuropeptide Y; Neuropeptides; Prednisone; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide; Vasomotor System | 1998 |
Subthreshold concentration of endothelin-1-enhanced, capsaicin-induced bronchoconstriction in anaesthetized guinea-pigs.
Topics: Aerosols; Airway Resistance; Anesthesia; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Guinea Pigs; Male; Neurokinin A; Oligopeptides; Peptides, Cyclic; Piperidines; Substance P | 1998 |
Sensory neuropeptides induce histamine release from bronchoalveolar lavage cells in both nonasthmatic coughers and cough variant asthmatics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Calcitonin Gene-Related Peptide; Cough; Female; Histamine Release; Humans; Male; Mast Cells; Middle Aged; Neuropeptides; Substance P | 2000 |
[The distribution of substance P in the lungs of asthmatic guinea-pigs and the influence of dexamethasone on the distribution].
Topics: Animals; Anti-Inflammatory Agents; Asthma; Dexamethasone; Guinea Pigs; Lung; Male; Random Allocation; Substance P | 1998 |
[P-selectin and tachykinins in bronchial hyperresponsiveness of asthma].
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Glucocorticoids; Humans; Male; Middle Aged; P-Selectin; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1999 |
The effect of substance P on neutrophil function in normal and asthmatic subjects.
Topics: Antibody-Dependent Cell Cytotoxicity; Asthma; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Substance P; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
WS9326A, a novel tachykinin antagonist isolated from Streptomyces violaceusniger no. 9326. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
Topics: Animals; Asthma; Fermentation; Guinea Pigs; In Vitro Techniques; Lactones; Microscopy, Electron, Scanning; Peptides, Cyclic; Streptomyces; Substance P; Tachykinins | 1992 |
Substance P and beta-endorphin-like immunoreactivity in lavage fluids of subjects with and without allergic asthma.
Topics: Adolescent; Adult; Asthma; beta-Endorphin; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Female; Humans; Male; Nasal Provocation Tests; Respiratory Hypersensitivity; Substance P | 1992 |
[Asthma due to airway inflammation].
Topics: Airway Resistance; Animals; Asthma; Bradykinin; Bronchi; Bronchial Hyperreactivity; Bronchitis; Cytokines; Humans; Leukocytes; Substance P | 1992 |
[Skin reactivity to substance P in asthmatics].
Topics: Adult; Asthma; Female; Humans; Male; Middle Aged; Neurokinin A; Peptide Fragments; Skin; Skin Tests; Substance P | 1990 |
[The inhibitory effect of disodium cromoglycate on substance P sensory nerve fibres].
Topics: Animals; Asthma; Bronchi; Cromolyn Sodium; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Nerve Fibers; Sensory Receptor Cells; Substance P | 1990 |
Rhesus monkey airway responses to substance P.
Topics: Administration, Inhalation; Airway Obstruction; Animals; Antigens, Helminth; Ascaris; Asthma; Female; Lung; Macaca mulatta; Male; Respiratory Function Tests; Skin; Substance P; Thiorphan | 1990 |
[Airway hyperresponsiveness and mucus secretion].
Topics: Asthma; Autonomic Nervous System; Bronchi; Exocrine Glands; Humans; Mucus; Platelet Activating Factor; Substance P | 1990 |
Substance p-induced cutaneous and bronchial reactions in children with bronchial asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Child; Child, Preschool; Erythema; Female; Forced Expiratory Volume; Histamine; Humans; Intradermal Tests; Lidocaine; Male; Substance P | 1991 |
Skin reactivity to substance P, not to neurokinin A, is increased in allergic asthmatics.
Topics: Adult; Asthma; Erythema; Female; Humans; Male; Middle Aged; Neurokinin A; Peptide Fragments; Skin; Substance P | 1990 |
Nedocromil sodium inhibits substance P-induced potentiation of cholinergic neural responses in the isolated innervated rabbit trachea.
Topics: Animals; Asthma; In Vitro Techniques; Nedocromil; Parasympathetic Nervous System; Quinolones; Rabbits; Substance P; Trachea | 1991 |
Substance P immunoreactive nerves in airways from asthmatics and nonasthmatics.
Topics: Adult; Aged; Asthma; Humans; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Lung; Middle Aged; Nerve Fibers; Substance P | 1991 |
Mucosal nerves in endobronchial biopsies in asthma and non-asthma.
Topics: Adult; Asthma; Biopsy; Bronchi; Calcitonin Gene-Related Peptide; Female; Humans; Male; Mucous Membrane; Substance P; Vasoactive Intestinal Peptide | 1991 |
Neutrophil chemotactic activity of PAF, histamine and neuromediators in bronchial asthma.
Topics: Adolescent; Adult; Asthma; Chemotaxis, Leukocyte; Histamine; Humans; Middle Aged; Neuropeptides; Neutrophils; Platelet Activating Factor; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1991 |
Understanding biological variability in susceptibility to respiratory disease.
Topics: Animals; Asthma; Atropine; Bronchoconstrictor Agents; Disease Susceptibility; Genetic Variation; Mice; Mice, Inbred Strains; Respiratory Hypersensitivity; Respiratory System; Substance P | 1991 |
Asthma as an axon reflex.
Topics: Asthma; Axons; Epithelium; Humans; Nerve Tissue Proteins; Reflex; Respiratory System; Sensory Receptor Cells; Substance P | 1986 |
Effect of inhaled substance P and neurokinin A on the airways of normal and asthmatic subjects.
Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Lung; Male; Neurokinin A; Neuropeptides; Random Allocation; Substance P | 1987 |
[The effect of substance P on denervation effects in allergic guinea pig asthma].
Topics: Animals; Asthma; Denervation; Guinea Pigs; Ovalbumin; Substance P | 1987 |
[Neuropeptide-induced cough in humans].
Topics: Animals; Asthma; Bronchitis; Cough; Humans; Substance P | 1989 |
Substance P activation of bronchoalveolar macrophages from asthmatic patients and normal subjects.
Topics: Adolescent; Adult; Aged; Asthma; Bronchoalveolar Lavage Fluid; Child; Female; Humans; In Vitro Techniques; Macrophage Activation; Macrophages; Male; Middle Aged; Substance P; Thromboxane B2 | 1989 |