Page last updated: 2024-08-23

substance p and Arthritis, Rheumatoid

substance p has been researched along with Arthritis, Rheumatoid in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (6.15)	18.7374
1990's	37 (56.92)	18.2507
2000's	13 (20.00)	29.6817
2010's	10 (15.38)	24.3611
2020's	1 (1.54)	2.80

Authors

Authors	Studies
Camargo, LL; Cerqueira, ARA; Costa, SKP; Denadai-Souza, A; Fernandes, ES; Ferro, ES; Gewehr, MCF; Lima, C; Muscará, MN; Schenka, AA; Teixeira, SA; Yshii, LM	1
Kashiwakura, JI; Kuroda, K; Mishima, S; Okamura, Y; Okayama, Y; Saito, S; Sasaki-Sakamoto, T; Tokuhashi, Y; Toyoshima, S	1
Barbosa-Cobos, RE; Becerril-Mendoza, LT; Flores-Estrada, J; Lugo-Zamudio, G; Moreno, J; Moreno-Eutimio, MA; Ramirez-Bello, J; Rodríguez-Henríquez, P; Torres-González, R	1
Kang, Q; Liu, J; Liu, X; Liu, XY; Mo, NL; Wang, YJ; Wu, Q; Zhao, Y	1
Guiducci, S; Manetti, M; Matucci-Cerinic, M; Nacci, F; Peruzzi, F; Romano, E; Terenzi, R	1
Hong, HS; Son, Y	1
Lisowska, B; Lisowski, A; Siewruk, K	2
Namiki, T; Suzuki, M; Ueno, K; Yamaura, K	1
Aramaki, T; Arima, K; Eguchi, K; Fujikawa, K; Fukuda, T; Ida, H; Iwamoto, N; Kawabe, Y; Kawakami, A; Kawashiri, SY; Matsuoka, N; Mine, M; Mizokami, A; Nakamura, H; Nakashima, M; Origuchi, T; Tamai, M; Ueki, Y; Yamasaki, S	1
Anders, S; Grifka, J; Ossyssek, B; Straub, RH	1
de Miguel, E; Hernanz, A; Martín-Mola, E; Medina, S	1
Blades, M; Brain, SD; Castro da Rocha, FA; Keeble, J; Pitzalis, C	1
Forsgren, S; Grimsholm, O; Rantapää-Dahlqvist, S	1
Green, PG	1
Matsubayashi, S; Matsumoto, S	1
Carleson, J; Haigh, R; Inglis, JJ; Kidd, BL; O'Shaughnessy, MC; Vetsika, EK; Winyard, PG	1
Davis, F; Ellman, M; Forsyth, CB; Im, HJ; Kim, GH; Li, X; Muddasani, P; Rangan, J; Thonar, EJ	1
Anders, S; Angele, P; Capellino, S; Dirmeier, M; Schubert, T; Straub, RH	1
Dalén, T; Forsgren, S; Grimsholm, O; Rantapää-Dahlqvist, S	1
Blake, DR; Garrett, N; Mapp, PI; Polak, JM; Salmon, M; Walsh, DA; Wharton, J	1
Wong, HY	1
Arnalich, F; de Miguel, E; Gijon-Banos, J; Hernanz, A; Martinez, M; Perez-Ayala, C; Vazquez, JJ	1
Menkès, CJ; Renoux, M	1
Arnalich, F; De Miguel, E; Gijón-Baños, J; Hernanz, A; Tato, E; Vázquez, JJ	1
de Kruyff, I; Heijnen, CJ; Helders, PJ; Hogeweg, JA; Kuis, W	1
Fukui, H; Hokaze, Y; Kikuchi, E; Kikukawa, M; Matsumoto, M; Matsumura, M; Oku, K; Takaya, A; Umemoto, N; Yamao, J	1
Mapp, PI	1
Alstergren, P; Appelgren, A; Appelgren, B; Kopp, S; Lundeberg, T; Theodorsson, E	1
Arnalich, F; De Miguel, E; Gijon, J; Hernanz, A; Perez-Ayala, C; Romera, N	1
Bruxelle, J; Cesselin, F; Laoussadi, S; Mauborgne, A; Menkes, CJ; Renoux, M	1
Fioravanti, A; Franci, A; Gelli, R; Marcolongo, R; Minari, C; Montemerani, M; Moscato, P	1
Davis, AJ; Grootveld, M; Hawkes, GE; Haycock, PR; Kidd, BL; Mapp, PI; Naughton, D; O'Brien, P	1
Carrabba, M; Galante, A; Manfredi, B; Panerai, AE; Pisati, R; Sacerdote, P	1
Hallett, MB; Lloyds, D; Neville, N	1
DiMaggio, DA; Krause, JE; McCarson, KE	1
Inagaki, C; Mishima, K; Ogawa, R; Otani, H; Tanabe, T	1
Appelgren, A; Appelgren, B; Kopp, S; Lundeberg, T; Theodorsson, E	1
Anichini, M; Cesaretti, S; Lepori, M; Maddali Bongi, S; Maresca, M; Zoppi, M	1
Bordin, G; Brunelleschi, S; Colangelo, D; Viano, I	2
Cantagrel, A; De Préval, C; Enault, G; Lambert, N; Lescoulié, PL; Mazières, B; Yassine-Diab, B	1
Abid, A; Chat, M; Decaris, E; Gillet, P; Grillasca, JP; Guingamp, C; Minn, A; Netter, P; Philippe, L; Terlain, B	1
Jüsten, HP; Miller, LE; Schölmerich, J; Straub, RH	1
Hirabayashi, K; Inoue, H; Kajigaya, H; Koshihara, Y; Oda, H; Shimoyama, Y; Yamamoto, S	1
Bordin, G; Brunelleschi, S; Colangelo, D; Lavagno, L; Viano, I	1
Grifka, J; Miller, LE; Schölmerich, J; Straub, RH	1
Bellinger, DL; Felten, DL; Felten, SY; Lorton, D	1
Agro, A; Stanisz, AM	1
Blake, DR; Kidd, BL; Mapp, PI; Polak, JM; Revell, PA; Rutherford, RA; Walsh, DA; Wharton, J	1
Tohyama, M	1
Chiu, B; Inman, RD; Marshall, KW	1
Fujimoto, K; Yokoyama, MM	1
Matucci-Cerinic, M; Partsch, G	1
Blake, DR; Gibson, SJ; Ibrahim, NB; Kidd, BL; Mapp, PI; Polak, JM; Revell, PA; Terry, JM	1
Brewerton, DA; Gibson, SJ; Grönblad, M; Hukkanen, M; Konttinen, YT; Polak, JM; Rees, R; Tolvanen, E	1
Carmo-Fonseca, M; Pereira da Silva, JA	1
Cagnoni, M; Jantsch, S; Marabini, S; Matucci-Cerinic, M; Partsch, G; Pignone, A	1
Ekblom, A; Hansson, P; Holmlund, A; Lind, J; Lundeberg, T; Theodorsson, E	1
Cagnoni, M; Del Bianco, E; Geppetti, P; Marabini, S; Marchesoni, A; Matucci-Cerinic, M; Partsch, G; Tosi, S	1
Appelgren, A; Appelgren, B; Eriksson, S; Kopp, S; Lundeberg, T; Nylander, M; Theodorsson, E	1
Basbaum, AI; Levine, JD; Moskowitz, MA	1
Basbaum, AI; Collier, DH; Helms, CA; Levine, JD; Moskowitz, MA	1
Carson, DA; Lotz, M; Vaughan, JH	1
Basbaum, AI; Goetzl, EJ; Levine, JD	1

Reviews

10 review(s) available for substance p and Arthritis, Rheumatoid

Article	Year
[Expression of the histamine H4 receptor in human tissues and its clinical role]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2010, Volume: 135, Issue:6 Topics: Animals; Arthritis, Rheumatoid; Cell Differentiation; Histamine Antagonists; Humans; Keratinocytes; Pruritus; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Skin; Substance P; Synovial Membrane	2010
Gastrin-releasing peptide, substance P and cytokines in rheumatoid arthritis. Arthritis research & therapy, 2005, Volume: 7, Issue:3 Topics: Animals; Arthritis, Rheumatoid; Cytokines; Gastrin-Releasing Peptide; Humans; Substance P	2005
[Substance P]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8 Topics: Arthritis, Rheumatoid; Biomarkers; Diagnostic Techniques, Endocrine; Humans; Immunoenzyme Techniques; Mood Disorders; Pain; Reagent Kits, Diagnostic; Respiratory Tract Diseases; Shock, Septic; Specimen Handling; Substance P	2005
Neural mechanisms of joint pain. Annals of the Academy of Medicine, Singapore, 1993, Volume: 22, Issue:4 Topics: Afferent Pathways; Animals; Arthritis, Rheumatoid; Humans; Joints; Nociceptors; Pain Threshold; Receptors, N-Methyl-D-Aspartate; Substance P; Sympathetic Nervous System	1993
[The effect of the nervous system on joint inflammations]. Nederlands tijdschrift voor geneeskunde, 1995, Jan-07, Volume: 139, Issue:1 Topics: Arthritis, Rheumatoid; Humans; Immune System; Nervous System; Neurons, Afferent; Neurons, Efferent; Substance P	1995
Innervation of the synovium. Annals of the rheumatic diseases, 1995, Volume: 54, Issue:5 Topics: Arthritis, Rheumatoid; Endopeptidases; Humans; Joints; Neurons, Afferent; Pain; Substance P; Synovial Membrane	1995
Alterations in neurokinin 1 receptor gene expression in models of pain and inflammation. Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:7 Topics: Animals; Arthritis, Rheumatoid; Gene Expression Regulation; Humans; Pain; Receptors, Neurokinin-1; Substance P	1995
[Neuropeptides in pathogenesis of arthritis]. Ryumachi. [Rheumatism], 1992, Volume: 32, Issue:2 Topics: Animals; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Guinea Pigs; Rats; Substance P	1992
Hypothesis: the nervous system may contribute to the pathophysiology of rheumatoid arthritis. The Journal of rheumatology, 1985, Volume: 12, Issue:3 Topics: Arthritis, Rheumatoid; Humans; Joints; Models, Biological; Nervous System; Peripheral Nerves; Substance P; Sympathetic Nervous System	1985
Contribution of the nervous system to the pathophysiology of rheumatoid arthritis and other polyarthritides. Rheumatic diseases clinics of North America, 1987, Volume: 13, Issue:2 Topics: Animals; Arthritis, Rheumatoid; Humans; Mice; Nervous System; Neuropeptides; Nociceptors; Rats; Substance P	1987

Trials

4 trial(s) available for substance p and Arthritis, Rheumatoid

Article	Year
The effect of gold salts on substance P levels in rheumatoid arthritis. Neuroscience letters, 1994, Jun-20, Volume: 174, Issue:2 Topics: Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Humans; Immunoassay; Male; Middle Aged; Substance P; Synovial Fluid	1994
[Evaluation of the efficacy of intra-articular administration of somatostatin in rheumatoid arthritis]. La Clinica terapeutica, 1993, Volume: 142, Issue:5 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Child; Child, Preschool; Drug Evaluation; Evaluation Studies as Topic; Female; Humans; Injections, Intra-Articular; Male; Middle Aged; Pain; Somatostatin; Substance P; Thermography	1993
Plasma and synovial fluid interleukin-1, interleukin-6 and substance P concentrations in rheumatoid arthritis patients: effect of the nonsteroidal anti inflammatory drugs indomethacin, diclofenac and naproxen. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:11 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Female; Humans; Indomethacin; Interleukin-1; Interleukin-6; Male; Middle Aged; Naproxen; Substance P; Synovial Fluid	1995
Substance P in the serum of patients with rheumatoid arthritis. Revue du rhumatisme (English ed.), 1997, Volume: 64, Issue:1 Topics: Adult; Aged; Arthritis, Rheumatoid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Prognosis; Sensitivity and Specificity; Substance P	1997

Other Studies

51 other study(ies) available for substance p and Arthritis, Rheumatoid

Article	Year
The potential anti-inflammatory and anti-nociceptive effects of rat hemopressin (PVNFKFLSH) in experimental arthritis. European journal of pharmacology, 2021, Jan-05, Volume: 890 Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Behavior, Animal; Cytokines; Edema; Gait; Hemoglobins; Inflammation; Injections, Intra-Articular; Knee Joint; Leukocytes; Male; Nociceptive Pain; Peptide Fragments; Rats, Sprague-Dawley; Receptors, Calcitonin Gene-Related Peptide; Substance P	2021
The dual regulation of substance P-mediated inflammation via human synovial mast cells in rheumatoid arthritis. Allergology international : official journal of the Japanese Society of Allergology, 2017, Volume: 66S Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Biomarkers; Cells, Cultured; Cytokines; Female; Fluorescent Antibody Technique; Gene Expression; Humans; Inflammation Mediators; Male; Mast Cells; Middle Aged; Osteoarthritis; RNA, Messenger; Substance P; Synoviocytes	2017
Serum substance P: an indicator of disease activity and subclinical inflammation in rheumatoid arthritis. Clinical rheumatology, 2018, Volume: 37, Issue:4 Topics: Adult; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Female; Humans; Inflammation; Male; Middle Aged; Severity of Illness Index; Substance P; Ultrasonography; Young Adult	2018
Transdermal delivery system of nanostructured lipid carriers loaded with Celastrol and Indomethacin: optimization, characterization and efficacy evaluation for rheumatoid arthritis. Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup3 Topics: Administration, Cutaneous; Animals; Arthritis, Rheumatoid; beta-Endorphin; Drug Carriers; Drug Liberation; Indomethacin; Interleukin-1beta; Pentacyclic Triterpenes; Rats; Rats, Sprague-Dawley; Skin Absorption; Substance P; Triterpenes; Tumor Necrosis Factor-alpha	2018
Neuropeptides activate TRPV1 in rheumatoid arthritis fibroblast-like synoviocytes and foster IL-6 and IL-8 production. Annals of the rheumatic diseases, 2013, Volume: 72, Issue:6 Topics: Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Capsaicin; Case-Control Studies; Humans; Interleukin-6; Interleukin-8; Substance P; Synovial Membrane; TRPV Cation Channels	2013
Substance P ameliorates collagen II-induced arthritis in mice via suppression of the inflammatory response. Biochemical and biophysical research communications, 2014, Oct-10, Volume: 453, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Progression; Humans; Immunosuppression Therapy; Interleukin-10; Interleukin-17; Macrophages; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred DBA; Substance P; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha	2014
Substance P and Chronic Pain in Patients with Chronic Inflammation of Connective Tissue. PloS one, 2015, Volume: 10, Issue:10 Topics: Arthritis, Rheumatoid; Chronic Pain; Connective Tissue; Female; Humans; Inflammation; Male; Middle Aged; Osteoarthritis; Substance P; Synovial Fluid; Synovial Membrane	2015
Substance P and Acute Pain in Patients Undergoing Orthopedic Surgery. PloS one, 2016, Volume: 11, Issue:1 Topics: Acute Pain; Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Female; Humans; Male; Middle Aged; Substance P	2016
Reduction in serum levels of substance P in patients with rheumatoid arthritis by etanercept, a tumor necrosis factor inhibitor. Modern rheumatology, 2011, Volume: 21, Issue:3 Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Calcitonin Gene-Related Peptide; Etanercept; Female; Gastrin-Releasing Peptide; Humans; Immunoglobulin G; Male; Middle Aged; Receptors, Tumor Necrosis Factor; Substance P; Tumor Necrosis Factor-alpha	2011
Surgical synovectomy decreases density of sensory nerve fibers in synovial tissue of non-inflamed controls and rheumatoid arthritis patients. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2011, Volume: 29, Issue:2 Topics: Adult; Aged; Arthritis, Rheumatoid; Case-Control Studies; Female; Humans; Knee Joint; Male; Middle Aged; Nociceptors; Substance P; Sympathetic Nervous System; Synovectomy; Synovial Membrane	2011
Effect of calcitonin gene-related peptide, neuropeptide Y, substance P, and vasoactive intestinal peptide on interleukin-1beta, interleukin-6 and tumor necrosis factor-alpha production by peripheral whole blood cells from rheumatoid arthritis and osteoart Regulatory peptides, 2003, Aug-15, Volume: 115, Issue:1 Topics: Aged; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Cytokines; Dose-Response Relationship, Drug; Female; Humans; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Middle Aged; Neuropeptide Y; Osteoarthritis; Peptides; Substance P; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide	2003
The role of substance P in microvascular responses in murine joint inflammation. British journal of pharmacology, 2005, Volume: 144, Issue:8 Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Knee Joint; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Receptors, Neurokinin-1; Substance P	2005
Levels of gastrin-releasing peptide and substance P in synovial fluid and serum correlate with levels of cytokines in rheumatoid arthritis. Arthritis research & therapy, 2005, Volume: 7, Issue:3 Topics: Adult; Arthritis, Rheumatoid; Cytokines; Female; Gastrin-Releasing Peptide; Humans; Male; Middle Aged; Neuroimmunomodulation; Substance P; Synovial Fluid	2005
The effect of substance P on nitric oxide release in a rheumatoid arthritis model. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2006, Volume: 55, Issue:6 Topics: Aged; Animals; Arthritis, Rheumatoid; Cells, Cultured; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Inflammation; Interleukin-1beta; Mice; Mice, Knockout; Middle Aged; Neurotransmitter Agents; Nitrates; Nitric Oxide; Nitrites; Receptors, Neurokinin-1; Substance P; Synovial Membrane; Tumor Necrosis Factor-alpha	2006
Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes. Journal of cellular physiology, 2008, Volume: 215, Issue:2 Topics: Adult; Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Chondrocytes; Extracellular Matrix; Fibroblast Growth Factor 2; Humans; Interleukin-1beta; Matrix Metalloproteinase 13; Matrix Metalloproteinases; Metabolism; Mitogen-Activated Protein Kinases; Neurosecretory Systems; NF-kappa B; Osteoarthritis; Proteoglycans; raf Kinases; Receptors, Neurokinin-1; Signal Transduction; Substance P; Synovial Fluid; Time Factors; Up-Regulation	2008
Lower density of synovial nerve fibres positive for calcitonin gene-related peptide relative to substance P in rheumatoid arthritis but not in osteoarthritis. Rheumatology (Oxford, England), 2008, Volume: 47, Issue:1 Topics: Aged; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Humans; Immunohistochemistry; Male; Nerve Fibers; Osteoarthritis, Knee; Substance P; Synovial Membrane; Synovitis	2008
Observations favouring the occurrence of local production and marked effects of bombesin/gastrin-releasing peptide in the synovial tissue of the human knee joint--comparisons with substance P and the NK-1 receptor. Neuropeptides, 2008, Volume: 42, Issue:2 Topics: Adult; Aged; Arthritis, Rheumatoid; Bombesin; Enzyme-Linked Immunosorbent Assay; Gastrin-Releasing Peptide; Humans; Immunohistochemistry; In Situ Hybridization; Knee Joint; Middle Aged; Osteoarthritis, Knee; Receptors, Neurokinin-1; RNA, Messenger; Staining and Labeling; Substance P; Synovial Membrane	2008
Microvascular substance P binding to normal and inflamed rat and human synovium. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2 Topics: Adult; Aged; Animals; Arthritis, Rheumatoid; Binding Sites; Endothelium, Vascular; Female; Humans; Iodine Radioisotopes; Knee Joint; Male; Middle Aged; Models, Biological; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; Succinimides; Synovial Membrane; Synovitis	1993
Neuropeptides and interleukin-6 in human joint inflammation relationship between intraarticular substance P and interleukin-6 concentrations. Neuroscience letters, 1994, Apr-11, Volume: 170, Issue:2 Topics: Arthritis, Rheumatoid; Female; Humans; Immunoenzyme Techniques; Interleukin-6; Knee Joint; Male; Middle Aged; Neuropeptides; Osmolar Concentration; Osteoarthritis; Radioimmunoassay; Substance P	1994
[Substance P and rheumatic diseases]. La Revue du praticien, 1994, Jun-15, Volume: 44, Issue:12 Topics: Animals; Arthritis, Rheumatoid; Chondrocalcinosis; Humans; Rheumatic Diseases; Substance P	1994
[Involvement of substance P in gastric mucosal lesions of patients with rheumatoid arthritis]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1995, Volume: 92, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gastric Mucosa; Humans; Rats; Rats, Wistar; Substance P	1995
Co-variation of neuropeptide Y, calcitonin gene-related peptide, substance P and neurokinin A in joint fluid from patients with temporomandibular joint arthritis. Archives of oral biology, 1995, Volume: 40, Issue:2 Topics: Adult; Aged; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Humans; Male; Middle Aged; Neurokinin A; Neuropeptide Y; Osteoarthritis; Regression Analysis; Spondylitis, Ankylosing; Substance P; Synovial Fluid; Temporomandibular Joint Disorders	1995
Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease. British journal of rheumatology, 1993, Volume: 32, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Gout; Humans; Male; Middle Aged; Osteoarthritis; Radioimmunoassay; Substance P; Synovial Fluid; Vasoactive Intestinal Peptide	1993
Substance P levels in the synovium and synovial fluid from patients with rheumatoid arthritis and osteoarthritis. The Journal of rheumatology, 1993, Volume: 20, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Humans; Middle Aged; Osteoarthritis; Radioimmunoassay; Substance P; Synovial Fluid; Synovial Membrane	1993
Generation of substance P carbamate in neutral aqueous solution. Relevance to inflammatory joint diseases. FEBS letters, 1993, Aug-30, Volume: 329, Issue:3 Topics: Arthritis, Rheumatoid; Carbamates; Humans; Magnetic Resonance Spectroscopy; Protons; Solutions; Substance P; Water	1993
Tyrosine phosphorylation in inflammatory neutrophils. Biochemical Society transactions, 1996, Volume: 24, Issue:1 Topics: Arthritis, Rheumatoid; Blotting, Western; Enzyme Inhibitors; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidoreductases; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Reference Values; Substance P; Synovial Fluid; Tyrosine; Vanadates	1996
Mechanisms of oxyradical production in substance P stimulated rheumatoid synovial cells. Rheumatology international, 1996, Volume: 16, Issue:4 Topics: Arthritis, Rheumatoid; Calcium; Cells, Cultured; Female; Free Radicals; Humans; Male; Substance P; Synovial Membrane	1996
Neuropeptides in the arthritic TMJ and symptoms and signs from the stomatognathic system with special consideration to rheumatoid arthritis. Journal of orofacial pain, 1995,Summer, Volume: 9, Issue:3 Topics: Adult; Arthritis; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Humans; Inflammation Mediators; Male; Middle Aged; Neuroimmunomodulation; Neurokinin A; Neuropeptide Y; Neuropeptides; Pain; Pain Measurement; Range of Motion, Articular; Statistics, Nonparametric; Substance P; Synovial Fluid; Temporomandibular Joint Disorders	1995
Tachykinin receptors are present on human monocytes and play a role in rheumatoid arthritis. Journal of chemotherapy (Florence, Italy), 1998, Volume: 10, Issue:2 Topics: Aged; Arthritis, Rheumatoid; Cell Separation; Female; Humans; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Superoxides; Tetradecanoylphorbol Acetate	1998
Substance P enhances cytokine-induced vascular cell adhesion molecule-1 (VCAM-1) expression on cultured rheumatoid fibroblast-like synoviocytes. Clinical and experimental immunology, 1998, Volume: 113, Issue:2 Topics: Arthritis, Rheumatoid; B7-1 Antigen; CD40 Antigens; CD58 Antigens; Drug Interactions; Fibroblasts; Flow Cytometry; Histocompatibility Antigens Class II; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-1; Receptors, Tachykinin; RNA, Messenger; Substance P; Synovial Membrane; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	1998
Tachykinin receptors on human monocytes: their involvement in rheumatoid arthritis. Neuropeptides, 1998, Volume: 32, Issue:3 Topics: Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Gene Expression; Humans; Male; Middle Aged; Monocytes; Neurokinin A; Neurokinin B; Receptors, Tachykinin; RNA, Messenger; Substance P; Superoxides; Tumor Necrosis Factor-alpha	1998
Evidence for neurogenic transmission inducing degenerative cartilage damage distant from local inflammation. Arthritis and rheumatism, 1999, Volume: 42, Issue:9 Topics: Animals; Arthritis, Rheumatoid; Freund's Adjuvant; Injections, Intra-Articular; Injections, Subcutaneous; Interleukin-6; Knee Joint; Male; Neurokinin-1 Receptor Antagonists; Prostaglandins; Rats; Rats, Wistar; Substance P; Synaptic Transmission; Turpentine	1999
The loss of sympathetic nerve fibers in the synovial tissue of patients with rheumatoid arthritis is accompanied by increased norepinephrine release from synovial macrophages. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:13 Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Chronic Disease; Cytokines; Electric Stimulation; Humans; Knee Joint; Macrophages; Middle Aged; Nerve Fibers; Norepinephrine; Osteoarthritis; Sensory Receptor Cells; Substance P; Sympathetic Nervous System; Synovial Membrane	2000
Production of neuropeptide substance P by synovial fibroblasts from patients with rheumatoid arthritis and osteoarthritis. Neuroscience letters, 2001, May-11, Volume: 303, Issue:3 Topics: Arthritis, Rheumatoid; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Fibroblasts; Humans; Immunohistochemistry; Nerve Fibers; Osteoarthritis; Protein Precursors; RNA, Messenger; Substance P; Synovial Membrane; Tachykinins; Transforming Growth Factor beta	2001
Tachykinin activation of human monocytes from patients with rheumatoid arthritis: in vitro and ex-vivo effects of cyclosporin A. Neuropeptides, 2001, Volume: 35, Issue:2 Topics: Arthritis, Rheumatoid; Carcinogens; Cells, Cultured; Cyclosporine; Humans; Immunosuppressive Agents; In Vitro Techniques; Monocytes; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Respiratory Burst; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha	2001
Norepinephrine from synovial tyrosine hydroxylase positive cells is a strong indicator of synovial inflammation in rheumatoid arthritis. The Journal of rheumatology, 2002, Volume: 29, Issue:3 Topics: Adrenergic Fibers; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Biomarkers; Cell Count; Cells, Cultured; Humans; Interleukin-6; Interleukin-8; Matrix Metalloproteinase 3; Middle Aged; Norepinephrine; Osteoarthritis; Predictive Value of Tests; Substance P; Synovial Membrane; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase	2002
Noradrenergic and peptidergic innervation of secondary lymphoid organs: role in experimental rheumatoid arthritis. European journal of clinical investigation, 1992, Volume: 22 Suppl 1 Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Denervation; Disease Models, Animal; In Vitro Techniques; Lymphoid Tissue; Male; Nerve Fibers; Norepinephrine; Rats; Rats, Inbred Lew; Substance P	1992
Are lymphocytes a target for substance P modulation in arthritis? Seminars in arthritis and rheumatism, 1992, Volume: 21, Issue:4 Topics: Adjuvants, Immunologic; Arthritis, Rheumatoid; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lymphocyte Activation; Lymphocytes; Substance P; Synovial Fluid; Synovial Membrane	1992
Localisation and characterisation of substance P binding to human synovial tissue in rheumatoid arthritis. Annals of the rheumatic diseases, 1992, Volume: 51, Issue:3 Topics: Adult; Aged; Arthritis, Rheumatoid; Autoradiography; Blood Vessels; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Substance P; Synovial Membrane	1992
Substance P and arthritis: analysis of plasma and synovial fluid levels. Arthritis and rheumatism, 1990, Volume: 33, Issue:1 Topics: Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Humans; Joints; Osteoarthritis; Substance P; Synovial Fluid; Wounds and Injuries	1990
Role of lymphocyte activation by substance P in rheumatoid arthritis. International journal of tissue reactions, 1990, Volume: 12, Issue:1 Topics: Antigens, CD; Antigens, Differentiation; Arthritis, Rheumatoid; HLA-DR Antigens; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Oxygen; Phytohemagglutinins; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P	1990
Effect of capsaicin on the release of substance P from rheumatoid arthritis and osteoarthritis synoviocytes in vitro. Annals of the rheumatic diseases, 1990, Volume: 49, Issue:8 Topics: Arthritis, Rheumatoid; Capsaicin; Humans; Osteoarthritis; Substance P; Synovial Fluid	1990
Substance P-, calcitonin gene-related peptide- and C-flanking peptide of neuropeptide Y-immunoreactive fibres are present in normal synovium but depleted in patients with rheumatoid arthritis. Neuroscience, 1990, Volume: 37, Issue:1 Topics: Adult; Aged; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Child; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neurons; Neuropeptide Y; Substance P; Synovial Membrane	1990
Nerves in inflammatory synovium: immunohistochemical observations on the adjuvant arthritis rat model. The Journal of rheumatology, 1990, Volume: 17, Issue:12 Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Disease Models, Animal; Humans; Immune Sera; Immunohistochemistry; Neuropeptides; Rats; Substance P; Synovial Membrane; Synovitis; Ubiquitin Thiolesterase	1990
Peptide containing nerves in human synovium: immunohistochemical evidence for decreased innervation in rheumatoid arthritis. The Journal of rheumatology, 1990, Volume: 17, Issue:12 Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Fluorescent Antibody Technique; Humans; Male; Middle Aged; Neuropeptide Y; Neuropeptides; Peptide Fragments; Substance P; Synovial Membrane; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase	1990
Collagenase synthesis of rheumatoid arthritis synoviocytes: dose-dependent stimulation by substance P and capsaicin. Scandinavian journal of rheumatology, 1991, Volume: 20, Issue:2 Topics: Arthritis, Rheumatoid; Capsaicin; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Microbial Collagenase; Substance P; Synovial Fluid; Synovial Membrane	1991
Concentrations of neuropeptides substance P, neurokinin A, calcitonin gene-related peptide, neuropeptide Y and vasoactive intestinal polypeptide in synovial fluid of the human temporomandibular joint. A correlation with symptoms, signs and arthroscopic fi International journal of oral and maxillofacial surgery, 1991, Volume: 20, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Arthroscopy; Calcitonin Gene-Related Peptide; Cartilage, Articular; Female; Humans; Male; Middle Aged; Neurokinin A; Neuropeptide Y; Neuropeptides; Osteoarthritis; Substance P; Synovial Fluid; Synovitis; Temporomandibular Joint; Temporomandibular Joint Disorders; Vasoactive Intestinal Peptide	1991
Substance P and somatostatin levels in rheumatoid arthritis, osteoarthritis, and psoriatic arthritis synovial fluid. Annals of the New York Academy of Sciences, 1991, Volume: 632 Topics: Arthritis; Arthritis, Rheumatoid; Humans; Osteoarthritis; Psoriasis; Somatostatin; Substance P; Synovial Fluid	1991
Neuropeptides in temporomandibular joints with rheumatoid arthritis: a clinical study. Scandinavian journal of dental research, 1991, Volume: 99, Issue:6 Topics: Adult; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Humans; Neurokinin A; Neuropeptide Y; Neuropeptides; Substance P; Synovial Fluid; Temporomandibular Joint Disorders	1991
The contribution of neurogenic inflammation in experimental arthritis. Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 135, Issue:2 Suppl Topics: Animals; Arthritis; Arthritis, Experimental; Arthritis, Rheumatoid; Brain Stem; Humans; Inflammation; Nociceptors; Pain; Rats; Spinal Cord; Substance P; Sympathetic Nervous System	1985
Substance P activation of rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis. Science (New York, N.Y.), 1987, Feb-20, Volume: 235, Issue:4791 Topics: Arthritis, Rheumatoid; Dinoprostone; Humans; In Vitro Techniques; Microbial Collagenase; Prostaglandins E; Substance P; Synovial Membrane	1987