substance p has been researched along with Anxiety in 50 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.00) | 18.7374 |
1990's | 9 (18.00) | 18.2507 |
2000's | 26 (52.00) | 29.6817 |
2010's | 12 (24.00) | 24.3611 |
2020's | 2 (4.00) | 2.80 |
Authors | Studies |
---|---|
Di, T; Fu, J; Guo, J; Li, N; Li, P; Meng, Y; Wang, Y; Zhang, L; Zhao, J | 1 |
Andersen, ML; Facina, AS; Tomimori, J; Tufik, S; Xerfan, EMS | 1 |
Bassi, GS; Brandão, ML; de Carvalho, MC | 1 |
Groffik, A; Hawro, T; Krull, C; Maurer, M; Metz, M; Saluja, R; Stanger, C; Staubach, P | 1 |
Cowie, P; Davidson, S; Hay, CW; Lear, M; MacKenzie, A; McEwan, IJ; McGuffin, P; Riedel, G; Shanley, L | 1 |
Huang, GY; Li, SQ; Tian, M; Wang, Y; Xiong, F; Zheng, CH | 1 |
Brandão, ML; Carvalho, MC; Santos, JM | 1 |
De Lima, TC; Duarte, FS; Duzzioni, M; Leme, LR; Smith, Sde P | 1 |
Baker, K; Barrett, JS; Barrett, K; Douglas, SD; Evans, DL; Lackner, A; Moorthy, G; Spitsin, S; Tulic, F; Winters, A | 1 |
Appleyard, CB; Cruz, ML; Hernandez, S; Seguinot, II; Torres-Reveron, A | 1 |
Ebner, K; Muigg, P; Singewald, G; Singewald, N | 1 |
Bassi, GS; Brandão, ML; Broiz, AC; Gomes, MZ | 1 |
Akhmedov, VA; Ostapenko, VA | 1 |
Antonelli, A; Barone, G; Chiaretti, A; Genovese, O; Lazzareschi, I; Maurizi, P; Paiano, S; Riccardi, R; Ruggiero, A; Sammartino, M | 1 |
Hwang, BH; June, HL; Mamczarz, J; Yang, AR; Yi, HS | 1 |
Bae, BG; Lee, KH; Noh, JY; Oh, SH; Park, CO; Park, IH; Wu, WH | 1 |
Bassi, GS; Brandão, ML; Brenes, JC; Broiz, AC; Schwarting, RK | 1 |
Barros, M; de Souza Silva, MA; Huston, JP; Melamed, JL; Müller, CP; Tomaz, C | 1 |
Canteras, NS; De Lima, TC; Gavioli, EC | 2 |
Bilkei-Gorzo, A; Michel, K; Racz, I; Zimmer, A | 1 |
De Felipe, C; Gadd, CA; Hunt, SP; Murtra, P | 1 |
De lima, TC; Teixeira, RM | 1 |
Ebner, K; Rupniak, NM; Saria, A; Singewald, N | 1 |
Duffy, RA | 1 |
Blier, P; Gobbi, G; Haddjeri, N; Hen, R; Mathew, G; Santarelli, L | 1 |
De Lima, TC; Duarte, FS; Teixeira, RM | 1 |
McLean, S | 1 |
Davidson, S; Dowell, A; Gildea, A; Mackenzie, A; Miller, KA | 1 |
Ebner, K; Singewald, N | 1 |
Branco, R; De Lima, TC; Madruga, D; Marcinichen, DR; Mello, DM; Paschoalini, MA | 1 |
Feige, B; Fiebich, BL; Herpfer, I; Katzev, M; Lieb, K; Voderholzer, U | 1 |
Calixto, AV; De Lima, TC; Duarte, FS; Duzzioni, M | 1 |
Brandão, ML; Carvalho, MC; de Souza Silva, MA; Masson, S | 1 |
Basso, N; D'Intinosante, V; Fioravanti, M; Ginaldi, A; Materia, A; Pona, V; Reilly, P; Ruggeri, S | 1 |
Flüge, T; Richter, S; Schedlowski, M; Schmidt, RE; Tewes, U; Wagner, TO | 1 |
Calixto, JB; De Lima, TC; Rae, GA; Ribeiro, SJ; Santos, AR; Teixeira, RM | 1 |
De Souza Silva, MA; Hasenöhrl, RU; Huston, JP; Jentjens, O; Tomaz, C | 1 |
Gol'dberg, SR; Medvedeva, OF; Rusakova, IV; Sudakov, SK; Terebilina, NN | 1 |
Calixto, JB; De Lima, TC; Ribeiro, SJ; Teixeira, RM | 1 |
Brandão, ML; De Araújo, JE; Huston, JP; Silva, RC | 1 |
Hasenöhrl, RU; Huston, JP; Nikolaus, S | 1 |
Brandao, ML; Hasenöhrl, RU; Huston, JP; Nikolaus, S; Schwarting, RK; Souza-Silva, MA; Tomaz, C | 1 |
Brugger, F; Gentsch, C; Hauser, K; Ofner, S; Schilling, W; Vassout, A; Veenstra, S | 1 |
Goldberg, SR; Medvedeva, OF; Rusakova, IV; Sudakov, SK; Terebilina, NN | 1 |
Lesch, KP | 1 |
Commons, KG; Valentino, RJ | 1 |
Barros, M; De Souza Silva, MA; Huston, JP; Tomaz, C | 1 |
Dietrich, H; Maggi, CA; Saria, A; Zernig, G | 1 |
Beal, MF; Vécsei, L | 1 |
5 review(s) available for substance p and Anxiety
Article | Year |
---|---|
Potential therapeutic targets for neurokinin-1 receptor antagonists.
Topics: Analgesics; Anti-Anxiety Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antiemetics; Antineoplastic Agents; Antitussive Agents; Anxiety; Asthma; Clinical Trials as Topic; Cough; Cystitis; Depression; Drug Design; Humans; Inflammation; Irritable Bowel Syndrome; Neoplasms; Neurokinin-1 Receptor Antagonists; Pain; Substance P; Vomiting | 2004 |
Do substance P and the NK1 receptor have a role in depression and anxiety?
Topics: Amygdala; Animals; Anxiety; Depression; Frontal Lobe; Humans; Locus Coeruleus; Neurokinin-1 Receptor Antagonists; Raphe Nuclei; Receptors, Neurokinin-1; Substance P | 2005 |
The role of substance P in stress and anxiety responses.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain; Depression; Humans; Hypothalamo-Hypophyseal System; Mood Disorders; Neurokinin-1 Receptor Antagonists; Pituitary-Adrenal System; Psychotropic Drugs; Receptors, Neurokinin-1; Serotonin; Stress, Physiological; Substance P; Synaptic Transmission | 2006 |
Substance P and its role in neural mechanisms governing learning, anxiety and functional recovery.
Topics: Animals; Anxiety; Brain Chemistry; Brain Diseases; Conditioning, Psychological; Recovery of Function; Substance P | 2000 |
Mouse anxiety: the power of knockout.
Topics: Animals; Anxiety; Mice; Mice, Knockout; Phenotype; Receptors, Neurokinin-1; Substance P | 2001 |
3 trial(s) available for substance p and Anxiety
Article | Year |
---|---|
Clinical study of electro-acupuncture treatment with different intensities for functional constipation patients.
Topics: Acupuncture Points; Adolescent; Adult; Analysis of Variance; Anxiety; Constipation; Defecation; Depression; Electroacupuncture; Female; Humans; Hydrocortisone; Male; Middle Aged; Outcome Assessment, Health Care; Substance P; Time Factors; Treatment Outcome; Vasoactive Intestinal Peptide; Young Adult | 2014 |
Effects of substance P on memory and mood in healthy male subjects.
Topics: Adult; Affect; Anxiety; Attention; Autonomic Nervous System; Cross-Over Studies; Depression; Double-Blind Method; Humans; Infusions, Intravenous; Male; Memory, Short-Term; Mental Recall; Neuropsychological Tests; Personality Inventory; Substance P; Vasodilation | 2007 |
Effect of ceruletide on pituitary-hypothalamic peptides and on emotion in man.
Topics: Adrenocorticotropic Hormone; Adult; Analgesia; Anxiety; beta-Endorphin; Ceruletide; Emotions; Endorphins; Growth Hormone; Histamine; Humans; Male; Prolactin; Substance P | 1981 |
42 other study(ies) available for substance p and Anxiety
Article | Year |
---|---|
Stress aggravates and prolongs imiquimod-induced psoriasis-like epidermal hyperplasis and IL-1β/IL-23p40 production.
Topics: Animals; Anxiety; Dendritic Cells; Dermatitis; Emotions; Epidermis; Hyperplasia; Imiquimod; Inflammation; Interleukin-12 Subunit p40; Interleukin-1beta; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Nociceptors; Psoriasis; Receptors, Neurokinin-1; Stress, Psychological; Substance P; Up-Regulation | 2020 |
The role of sleep in telogen effluvium and trichodynia: A commentary in the context of the current pandemic.
Topics: Animals; Anxiety; COVID-19; Hair Diseases; Humans; Mice; SARS-CoV-2; Sleep; Sleep Wake Disorders; Stress, Psychological; Substance P | 2021 |
Effects of substance P and Sar-Met-SP, a NK1 agonist, in distinct amygdaloid nuclei on anxiety-like behavior in rats.
Topics: Animals; Anxiety; Central Amygdaloid Nucleus; Corticomedial Nuclear Complex; Male; Maze Learning; Microinjections; Rats, Wistar; Receptors, Neurokinin-1; Substance P | 2014 |
Substance P is upregulated in the serum of patients with chronic spontaneous urticaria.
Topics: Anxiety; Biomarkers; Chronic Disease; Depression; Disease Progression; Germany; Humans; Quality of Life; Severity of Illness Index; Substance P; Up-Regulation; Urticaria | 2014 |
Functional effects of polymorphisms on glucocorticoid receptor modulation of human anxiogenic substance-P gene promoter activity in primary amygdala neurones.
Topics: Amygdala; Animals; Animals, Newborn; Anxiety; Base Sequence; Cells, Cultured; Colforsin; Dexamethasone; Gene Expression Regulation; Humans; Molecular Sequence Data; Neurons; Polymorphism, Single Nucleotide; Primary Cell Culture; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Sequence Homology, Nucleic Acid; Substance P | 2014 |
Dorsal periaqueductal gray post-stimulation freezing is counteracted by neurokinin-1 receptor antagonism in the central nucleus of the amygdala in rats.
Topics: Animals; Anxiety; Central Amygdaloid Nucleus; Electric Stimulation; Escape Reaction; Fear; Male; Memory; Neurokinin-1 Receptor Antagonists; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P | 2015 |
Evidence for involvement of NK₃ receptors in the anxiogenic-like effect of SP6-11(C-terminal), a metabolite of substance P, in rats evaluated in the elevated plus-maze.
Topics: Animals; Anxiety; Male; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Neurokinin-3; Substance P | 2016 |
Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV.
Topics: Adolescent; Adult; Animals; Anti-Inflammatory Agents; Anxiety; Aprepitant; Chemokines; Female; HIV Infections; Humans; Macaca mulatta; Macrophages; Male; Middle Aged; Monocytes; Morpholines; Neurokinin-1 Receptor Antagonists; Protein Binding; Receptors, Neurokinin-1; Simian Acquired Immunodeficiency Syndrome; Substance P; Viral Load; Virus Replication; Young Adult | 2016 |
Impact of Psychological Stress on Pain Perception in an Animal Model of Endometriosis.
Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Endometriosis; Enkephalins; Female; Oligopeptides; Pain Measurement; Pain Perception; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, mu; Spinal Cord; Stress, Psychological; Substance P | 2017 |
Substance P in stress and anxiety: NK-1 receptor antagonism interacts with key brain areas of the stress circuitry.
Topics: Animals; Anxiety; Brain; Genes, fos; Male; Maze Learning; Models, Biological; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Stress, Physiological; Substance P | 2008 |
Evidence for mediation of nociception by injection of the NK-3 receptor agonist, senktide, into the dorsal periaqueductal gray of rats.
Topics: Animals; Anxiety; Exploratory Behavior; Fear; Male; Maze Learning; Microinjections; Motor Activity; Pain Measurement; Peptide Fragments; Periaqueductal Gray; Quinolines; Rats; Rats, Wistar; Receptors, Neurokinin-3; Substance P; Ultrasonics; Vocalization, Animal | 2009 |
[Psychoemotional and humoral changes in patients with combined reflux disorders].
Topics: Adolescent; Adult; Affective Symptoms; Anxiety; Autonomic Nervous System; Case-Control Studies; Depression; Duodenogastric Reflux; Female; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Male; Middle Aged; Neuropsychological Tests; Psychophysiologic Disorders; Substance P; Young Adult | 2009 |
Propofol/alfentanil and propofol/ketamine procedural sedation in children with acute lymphoblastic leukaemia: safety, efficacy and their correlation with pain neuromediator expression.
Topics: Adolescent; Alfentanil; Anxiety; Child; Child, Preschool; Conscious Sedation; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Ketamine; Male; Nerve Growth Factor; Pain; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Propofol; Prospective Studies; Spinal Puncture; Substance P; Treatment Outcome | 2010 |
Deficits in substance P mRNA levels in the CeA are inversely associated with alcohol-motivated responding.
Topics: Alcoholism; Amygdala; Animals; Anxiety; Autoradiography; Behavior, Addictive; Central Nervous System Depressants; Ethanol; In Situ Hybridization; Male; Motivation; Rats; RNA, Messenger; Substance P | 2009 |
Association of stress with symptoms of atopic dermatitis.
Topics: Adolescent; Adult; Anxiety; Biopsy; Case-Control Studies; Child; Depression; Dermatitis, Atopic; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nerve Growth Factor; Neuropeptide Y; Prognosis; Pruritus; Quality of Life; Receptors, Corticotropin-Releasing Hormone; Republic of Korea; Severity of Illness Index; Skin; Stress, Psychological; Substance P; Surveys and Questionnaires; Young Adult | 2010 |
Involvement of midbrain tectum neurokinin-mediated mechanisms in fear and anxiety.
Topics: Animals; Anxiety; Avoidance Learning; Electric Stimulation; Escape Reaction; Fear; Inferior Colliculi; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Periaqueductal Gray; Rats; Rats, Wistar; Substance P; Vocalization, Animal | 2012 |
Sensitization of hypervigilance effects of cocaine can be induced by NK3 receptor activation in marmoset monkeys.
Topics: Animals; Anxiety; Behavior, Animal; Callithrix; Cocaine; Dopamine Uptake Inhibitors; Motor Activity; Peptide Fragments; Receptors, Neurokinin-3; Substance P | 2013 |
The role of lateral septal NK1 receptors in mediating anxiogenic effects induced by intracerebroventricular injection of substance P.
Topics: Animals; Anxiety; Dipeptides; Grooming; Indoles; Injections, Intraventricular; Male; Neurokinin-1 Receptor Antagonists; Posture; Rats; Rats, Wistar; Receptors, Neurokinin-1; Septum of Brain; Substance P | 2002 |
Diminished anxiety- and depression-related behaviors in mice with selective deletion of the Tac1 gene.
Topics: Animals; Anxiety; Behavior, Animal; Depression; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Motor Activity; Neurokinin A; Neurosurgical Procedures; Olfactory Bulb; Smell; Social Behavior; Spatial Behavior; Stress, Physiological; Substance P | 2002 |
Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Psychological; Crosses, Genetic; Drug Administration Routes; Illicit Drugs; Immunotoxins; Male; Maze Learning; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Narcotics; Neurons; Nucleus Accumbens; Receptors, Neurokinin-1; Reward; Ribosome Inactivating Proteins, Type 1; Saporins; Spatial Behavior; Substance P | 2003 |
Involvement of tachykinin NK1 receptor in the behavioral and immunological responses to swimming stress in mice.
Topics: Animals; Anxiety; Behavior, Animal; Dipeptides; Indoles; Injections, Intraventricular; Leukocyte Count; Maze Learning; Mice; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Stress, Physiological; Substance P; Swimming | 2003 |
Substance P in the medial amygdala: emotional stress-sensitive release and modulation of anxiety-related behavior in rats.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Male; Microinjections; Rats; Rats, Sprague-Dawley; Stress, Physiological; Substance P | 2004 |
Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response.
Topics: Adrenergic alpha-Agonists; Animals; Antiemetics; Anxiety; Aprepitant; Autoreceptors; Depressive Disorder, Major; Electrophysiology; Hippocampus; Locus Coeruleus; Mice; Mice, Mutant Strains; Morpholines; Neurokinin-1 Receptor Antagonists; Norepinephrine; Phenylephrine; Photomicrography; Raphe Nuclei; Receptors, Neurokinin-1; Serotonin; Substance P | 2004 |
Behavioral and immunological effects of substance P in female and male mice.
Topics: Animals; Anxiety; Behavior, Animal; Female; Grooming; Immunity; Injections, Intraventricular; Leukocyte Count; Lymphocyte Count; Macrophage Activation; Macrophages; Male; Mice; Motor Activity; Neutrophils; Nitric Oxide; Sex Characteristics; Substance P | 2004 |
A remote and highly conserved enhancer supports amygdala specific expression of the gene encoding the anxiogenic neuropeptide substance-P.
Topics: Amygdala; Animals; Anxiety; Base Sequence; Cells, Cultured; Chickens; Computational Biology; Conserved Sequence; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Developmental; Homeodomain Proteins; Humans; Mice; Mice, Transgenic; Molecular Sequence Data; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Protein Precursors; Sequence Homology, Nucleic Acid; Substance P; Tachykinins; Transcription Factors | 2006 |
Involvement of NK1 receptors in metabolic stress markers after the central administration of substance P.
Topics: Analysis of Variance; Animals; Anxiety; Biomarkers; Blood Glucose; Corticosterone; Energy Metabolism; Fatty Acids, Nonesterified; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Neurokinin-1; Signal Transduction; Stress, Physiological; Substance P | 2007 |
Modulation of anxiety in rats evaluated in the elevated T-maze: evidence of the relationship between substance P and diazepam.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Diazepam; Dipeptides; Fear; Indoles; Injections, Intraperitoneal; Injections, Intraventricular; Male; Memory; Neurokinin-1 Receptor Antagonists; Rats; Rats, Wistar; Substance P | 2008 |
Anxiolytic-like effects of substance P administration into the dorsal, but not ventral, hippocampus and its influence on serotonin.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Microdialysis; Microinjections; Rats; Rats, Wistar; Serotonin; Substance P | 2008 |
Beta-endorphin, but not substance-P, is increased by acute stress in humans.
Topics: Adult; Anxiety; Arousal; Aviation; beta-Endorphin; Humans; Internal-External Control; Male; Personality Inventory; Stress, Psychological; Substance P | 1995 |
Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzamides; Dipeptides; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Mice; Motor Activity; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Postural Balance; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P | 1996 |
Anxiolytic-like action of neurokinin substance P administered systemically or into the nucleus basalis magnocellularis region.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Fear; Male; Maze Learning; Rats; Rats, Wistar; Social Behavior; Substance P; Substantia Innominata | 1998 |
[Changes in levels of substance P, peptide suppressing diazepam binding, and neuropeptide Y in the brain of high- and low-anxiety inbred rats during stress].
Topics: Animals; Anxiety; Brain; Diazepam; Hippocampus; Hypothalamus; Mesencephalon; Neuropeptide Y; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, GABA-A; Stress, Psychological; Substance P | 1999 |
Anxiogenic-like effect induced by substance P injected into the lateral septal nucleus.
Topics: Animals; Anxiety; Injections; Injections, Intraventricular; Lateral Ventricles; Male; Motor Activity; Rats; Rats, Wistar; Septal Nuclei; Substance P | 1999 |
Tachykinin NK(3)receptor involvement in anxiety.
Topics: Animals; Anxiety; Cerebral Ventricles; Injections, Intraventricular; Male; Maze Learning; Mice; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-3; Substance P; Tachykinins | 1999 |
Anxiogenic effects of substance P and its 7-11 C terminal, but not the 1-7 N terminal, injected into the dorsal periaqueductal gray.
Topics: Animals; Anxiety; Behavior, Animal; Male; Peptide Fragments; Periaqueductal Gray; Rats; Rats, Wistar; Substance P | 1999 |
Anxiolytic-like effects in rats produced by ventral pallidal injection of both N- and C-terminal fragments of substance P.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Basal Nucleus of Meynert; Globus Pallidus; Male; Maze Learning; Protein Structure, Tertiary; Rats; Rats, Wistar; Substance P | 2000 |
NKP608: a selective NK-1 receptor antagonist with anxiolytic-like effects in the social interaction and social exploration test in rats.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cattle; Dose-Response Relationship, Drug; Gerbillinae; Hindlimb; Humans; Inhibitory Concentration 50; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Protein Binding; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Social Behavior; Species Specificity; Substance P; Tumor Cells, Cultured | 2000 |
Differences in genetic predisposition to high anxiety in two inbred rat strains: role of substance P, diazepam binding inhibitor fragment and neuropeptide Y.
Topics: Animals; Anxiety; Behavior, Animal; Genetic Predisposition to Disease; Hippocampus; Hypothalamus; Male; Mesencephalon; Neuropeptide Y; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Species Specificity; Stress, Physiological; Substance P | 2001 |
Cellular basis for the effects of substance P in the periaqueductal gray and dorsal raphe nucleus.
Topics: Animals; Anxiety; Dendrites; Enkephalins; Glutamic Acid; Immunohistochemistry; Male; Microscopy, Electron; Neurons; Pain; Periaqueductal Gray; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Serotonin; Substance P; Synaptic Transmission; Tryptophan Hydroxylase | 2002 |
Anxiolytic-like effects of substance P fragment (SP(1-7)) in non-human primates (Callithrix penicillata).
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Callithrix; Exploratory Behavior; Fear; Female; Male; Maze Learning; Peptide Fragments; Predatory Behavior; Substance P | 2002 |
The substance P (NK1) receptor antagonist (+/-)-CP-96,345 causes sedation and motor impairment in Swiss albino mice in the black-and-white box behavioral paradigm.
Topics: Animals; Anxiety; Biphenyl Compounds; Depression, Chemical; Exploratory Behavior; Hypnotics and Sedatives; Male; Mice; Motor Activity; Naloxone; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Opioid; Rotation; Substance P | 1992 |
Comparative behavioral and neurochemical studies with striatal kainic acid- or quinolinic acid-lesioned rats.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Body Weight; Brain Chemistry; Corpus Striatum; Exploratory Behavior; gamma-Aminobutyric Acid; Kainic Acid; Male; Motor Activity; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Rotation; Substance P | 1991 |