Page last updated: 2024-08-23

substance p and Anxiety

substance p has been researched along with Anxiety in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.00)	18.7374
1990's	9 (18.00)	18.2507
2000's	26 (52.00)	29.6817
2010's	12 (24.00)	24.3611
2020's	2 (4.00)	2.80

Authors

Authors	Studies
Di, T; Fu, J; Guo, J; Li, N; Li, P; Meng, Y; Wang, Y; Zhang, L; Zhao, J	1
Andersen, ML; Facina, AS; Tomimori, J; Tufik, S; Xerfan, EMS	1
Bassi, GS; Brandão, ML; de Carvalho, MC	1
Groffik, A; Hawro, T; Krull, C; Maurer, M; Metz, M; Saluja, R; Stanger, C; Staubach, P	1
Cowie, P; Davidson, S; Hay, CW; Lear, M; MacKenzie, A; McEwan, IJ; McGuffin, P; Riedel, G; Shanley, L	1
Huang, GY; Li, SQ; Tian, M; Wang, Y; Xiong, F; Zheng, CH	1
Brandão, ML; Carvalho, MC; Santos, JM	1
De Lima, TC; Duarte, FS; Duzzioni, M; Leme, LR; Smith, Sde P	1
Baker, K; Barrett, JS; Barrett, K; Douglas, SD; Evans, DL; Lackner, A; Moorthy, G; Spitsin, S; Tulic, F; Winters, A	1
Appleyard, CB; Cruz, ML; Hernandez, S; Seguinot, II; Torres-Reveron, A	1
Ebner, K; Muigg, P; Singewald, G; Singewald, N	1
Bassi, GS; Brandão, ML; Broiz, AC; Gomes, MZ	1
Akhmedov, VA; Ostapenko, VA	1
Antonelli, A; Barone, G; Chiaretti, A; Genovese, O; Lazzareschi, I; Maurizi, P; Paiano, S; Riccardi, R; Ruggiero, A; Sammartino, M	1
Hwang, BH; June, HL; Mamczarz, J; Yang, AR; Yi, HS	1
Bae, BG; Lee, KH; Noh, JY; Oh, SH; Park, CO; Park, IH; Wu, WH	1
Bassi, GS; Brandão, ML; Brenes, JC; Broiz, AC; Schwarting, RK	1
Barros, M; de Souza Silva, MA; Huston, JP; Melamed, JL; Müller, CP; Tomaz, C	1
Canteras, NS; De Lima, TC; Gavioli, EC	2
Bilkei-Gorzo, A; Michel, K; Racz, I; Zimmer, A	1
De Felipe, C; Gadd, CA; Hunt, SP; Murtra, P	1
De lima, TC; Teixeira, RM	1
Ebner, K; Rupniak, NM; Saria, A; Singewald, N	1
Duffy, RA	1
Blier, P; Gobbi, G; Haddjeri, N; Hen, R; Mathew, G; Santarelli, L	1
De Lima, TC; Duarte, FS; Teixeira, RM	1
McLean, S	1
Davidson, S; Dowell, A; Gildea, A; Mackenzie, A; Miller, KA	1
Ebner, K; Singewald, N	1
Branco, R; De Lima, TC; Madruga, D; Marcinichen, DR; Mello, DM; Paschoalini, MA	1
Feige, B; Fiebich, BL; Herpfer, I; Katzev, M; Lieb, K; Voderholzer, U	1
Calixto, AV; De Lima, TC; Duarte, FS; Duzzioni, M	1
Brandão, ML; Carvalho, MC; de Souza Silva, MA; Masson, S	1
Basso, N; D'Intinosante, V; Fioravanti, M; Ginaldi, A; Materia, A; Pona, V; Reilly, P; Ruggeri, S	1
Flüge, T; Richter, S; Schedlowski, M; Schmidt, RE; Tewes, U; Wagner, TO	1
Calixto, JB; De Lima, TC; Rae, GA; Ribeiro, SJ; Santos, AR; Teixeira, RM	1
De Souza Silva, MA; Hasenöhrl, RU; Huston, JP; Jentjens, O; Tomaz, C	1
Gol'dberg, SR; Medvedeva, OF; Rusakova, IV; Sudakov, SK; Terebilina, NN	1
Calixto, JB; De Lima, TC; Ribeiro, SJ; Teixeira, RM	1
Brandão, ML; De Araújo, JE; Huston, JP; Silva, RC	1
Hasenöhrl, RU; Huston, JP; Nikolaus, S	1
Brandao, ML; Hasenöhrl, RU; Huston, JP; Nikolaus, S; Schwarting, RK; Souza-Silva, MA; Tomaz, C	1
Brugger, F; Gentsch, C; Hauser, K; Ofner, S; Schilling, W; Vassout, A; Veenstra, S	1
Goldberg, SR; Medvedeva, OF; Rusakova, IV; Sudakov, SK; Terebilina, NN	1
Lesch, KP	1
Commons, KG; Valentino, RJ	1
Barros, M; De Souza Silva, MA; Huston, JP; Tomaz, C	1
Dietrich, H; Maggi, CA; Saria, A; Zernig, G	1
Beal, MF; Vécsei, L	1

Reviews

5 review(s) available for substance p and Anxiety

Article	Year
Potential therapeutic targets for neurokinin-1 receptor antagonists. Expert opinion on emerging drugs, 2004, Volume: 9, Issue:1 Topics: Analgesics; Anti-Anxiety Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antiemetics; Antineoplastic Agents; Antitussive Agents; Anxiety; Asthma; Clinical Trials as Topic; Cough; Cystitis; Depression; Drug Design; Humans; Inflammation; Irritable Bowel Syndrome; Neoplasms; Neurokinin-1 Receptor Antagonists; Pain; Substance P; Vomiting	2004
Do substance P and the NK1 receptor have a role in depression and anxiety? Current pharmaceutical design, 2005, Volume: 11, Issue:12 Topics: Amygdala; Animals; Anxiety; Depression; Frontal Lobe; Humans; Locus Coeruleus; Neurokinin-1 Receptor Antagonists; Raphe Nuclei; Receptors, Neurokinin-1; Substance P	2005
The role of substance P in stress and anxiety responses. Amino acids, 2006, Volume: 31, Issue:3 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain; Depression; Humans; Hypothalamo-Hypophyseal System; Mood Disorders; Neurokinin-1 Receptor Antagonists; Pituitary-Adrenal System; Psychotropic Drugs; Receptors, Neurokinin-1; Serotonin; Stress, Physiological; Substance P; Synaptic Transmission	2006
Substance P and its role in neural mechanisms governing learning, anxiety and functional recovery. Neuropeptides, 2000, Volume: 34, Issue:5 Topics: Animals; Anxiety; Brain Chemistry; Brain Diseases; Conditioning, Psychological; Recovery of Function; Substance P	2000
Mouse anxiety: the power of knockout. The pharmacogenomics journal, 2001, Volume: 1, Issue:3 Topics: Animals; Anxiety; Mice; Mice, Knockout; Phenotype; Receptors, Neurokinin-1; Substance P	2001

Trials

3 trial(s) available for substance p and Anxiety

Article	Year
Clinical study of electro-acupuncture treatment with different intensities for functional constipation patients. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2014, Volume: 34, Issue:5 Topics: Acupuncture Points; Adolescent; Adult; Analysis of Variance; Anxiety; Constipation; Defecation; Depression; Electroacupuncture; Female; Humans; Hydrocortisone; Male; Middle Aged; Outcome Assessment, Health Care; Substance P; Time Factors; Treatment Outcome; Vasoactive Intestinal Peptide; Young Adult	2014
Effects of substance P on memory and mood in healthy male subjects. Human psychopharmacology, 2007, Volume: 22, Issue:8 Topics: Adult; Affect; Anxiety; Attention; Autonomic Nervous System; Cross-Over Studies; Depression; Double-Blind Method; Humans; Infusions, Intravenous; Male; Memory, Short-Term; Mental Recall; Neuropsychological Tests; Personality Inventory; Substance P; Vasodilation	2007
Effect of ceruletide on pituitary-hypothalamic peptides and on emotion in man. Peptides, 1981, Volume: 2 Suppl 2 Topics: Adrenocorticotropic Hormone; Adult; Analgesia; Anxiety; beta-Endorphin; Ceruletide; Emotions; Endorphins; Growth Hormone; Histamine; Humans; Male; Prolactin; Substance P	1981

Other Studies

42 other study(ies) available for substance p and Anxiety

Article	Year
Stress aggravates and prolongs imiquimod-induced psoriasis-like epidermal hyperplasis and IL-1β/IL-23p40 production. Journal of leukocyte biology, 2020, Volume: 108, Issue:1 Topics: Animals; Anxiety; Dendritic Cells; Dermatitis; Emotions; Epidermis; Hyperplasia; Imiquimod; Inflammation; Interleukin-12 Subunit p40; Interleukin-1beta; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Neurotransmitter Agents; Nociceptors; Psoriasis; Receptors, Neurokinin-1; Stress, Psychological; Substance P; Up-Regulation	2020
The role of sleep in telogen effluvium and trichodynia: A commentary in the context of the current pandemic. Journal of cosmetic dermatology, 2021, Volume: 20, Issue:4 Topics: Animals; Anxiety; COVID-19; Hair Diseases; Humans; Mice; SARS-CoV-2; Sleep; Sleep Wake Disorders; Stress, Psychological; Substance P	2021
Effects of substance P and Sar-Met-SP, a NK1 agonist, in distinct amygdaloid nuclei on anxiety-like behavior in rats. Neuroscience letters, 2014, May-21, Volume: 569 Topics: Animals; Anxiety; Central Amygdaloid Nucleus; Corticomedial Nuclear Complex; Male; Maze Learning; Microinjections; Rats, Wistar; Receptors, Neurokinin-1; Substance P	2014
Substance P is upregulated in the serum of patients with chronic spontaneous urticaria. The Journal of investigative dermatology, 2014, Volume: 134, Issue:11 Topics: Anxiety; Biomarkers; Chronic Disease; Depression; Disease Progression; Germany; Humans; Quality of Life; Severity of Illness Index; Substance P; Up-Regulation; Urticaria	2014
Functional effects of polymorphisms on glucocorticoid receptor modulation of human anxiogenic substance-P gene promoter activity in primary amygdala neurones. Psychoneuroendocrinology, 2014, Volume: 47 Topics: Amygdala; Animals; Animals, Newborn; Anxiety; Base Sequence; Cells, Cultured; Colforsin; Dexamethasone; Gene Expression Regulation; Humans; Molecular Sequence Data; Neurons; Polymorphism, Single Nucleotide; Primary Cell Culture; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Sequence Homology, Nucleic Acid; Substance P	2014
Dorsal periaqueductal gray post-stimulation freezing is counteracted by neurokinin-1 receptor antagonism in the central nucleus of the amygdala in rats. Neurobiology of learning and memory, 2015, Volume: 121 Topics: Animals; Anxiety; Central Amygdaloid Nucleus; Electric Stimulation; Escape Reaction; Fear; Male; Memory; Neurokinin-1 Receptor Antagonists; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P	2015
Evidence for involvement of NK₃ receptors in the anxiogenic-like effect of SP6-11(C-terminal), a metabolite of substance P, in rats evaluated in the elevated plus-maze. Behavioural brain research, 2016, Apr-15, Volume: 303 Topics: Animals; Anxiety; Male; Peptide Fragments; Piperidines; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Neurokinin-3; Substance P	2016
Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV. Journal of translational medicine, 2016, 05-26, Volume: 14, Issue:1 Topics: Adolescent; Adult; Animals; Anti-Inflammatory Agents; Anxiety; Aprepitant; Chemokines; Female; HIV Infections; Humans; Macaca mulatta; Macrophages; Male; Middle Aged; Monocytes; Morpholines; Neurokinin-1 Receptor Antagonists; Protein Binding; Receptors, Neurokinin-1; Simian Acquired Immunodeficiency Syndrome; Substance P; Viral Load; Virus Replication; Young Adult	2016
Impact of Psychological Stress on Pain Perception in an Animal Model of Endometriosis. Reproductive sciences (Thousand Oaks, Calif.), 2017, Volume: 24, Issue:10 Topics: Animals; Anxiety; Corticosterone; Disease Models, Animal; Endometriosis; Enkephalins; Female; Oligopeptides; Pain Measurement; Pain Perception; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, mu; Spinal Cord; Stress, Psychological; Substance P	2017
Substance P in stress and anxiety: NK-1 receptor antagonism interacts with key brain areas of the stress circuitry. Annals of the New York Academy of Sciences, 2008, Volume: 1144 Topics: Animals; Anxiety; Brain; Genes, fos; Male; Maze Learning; Models, Biological; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Stress, Physiological; Substance P	2008
Evidence for mediation of nociception by injection of the NK-3 receptor agonist, senktide, into the dorsal periaqueductal gray of rats. Psychopharmacology, 2009, Volume: 204, Issue:1 Topics: Animals; Anxiety; Exploratory Behavior; Fear; Male; Maze Learning; Microinjections; Motor Activity; Pain Measurement; Peptide Fragments; Periaqueductal Gray; Quinolines; Rats; Rats, Wistar; Receptors, Neurokinin-3; Substance P; Ultrasonics; Vocalization, Animal	2009
[Psychoemotional and humoral changes in patients with combined reflux disorders]. Terapevticheskii arkhiv, 2009, Volume: 81, Issue:2 Topics: Adolescent; Adult; Affective Symptoms; Anxiety; Autonomic Nervous System; Case-Control Studies; Depression; Duodenogastric Reflux; Female; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Male; Middle Aged; Neuropsychological Tests; Psychophysiologic Disorders; Substance P; Young Adult	2009
Propofol/alfentanil and propofol/ketamine procedural sedation in children with acute lymphoblastic leukaemia: safety, efficacy and their correlation with pain neuromediator expression. European journal of cancer care, 2010, Volume: 19, Issue:2 Topics: Adolescent; Alfentanil; Anxiety; Child; Child, Preschool; Conscious Sedation; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Ketamine; Male; Nerve Growth Factor; Pain; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Propofol; Prospective Studies; Spinal Puncture; Substance P; Treatment Outcome	2010
Deficits in substance P mRNA levels in the CeA are inversely associated with alcohol-motivated responding. Synapse (New York, N.Y.), 2009, Volume: 63, Issue:11 Topics: Alcoholism; Amygdala; Animals; Anxiety; Autoradiography; Behavior, Addictive; Central Nervous System Depressants; Ethanol; In Situ Hybridization; Male; Motivation; Rats; RNA, Messenger; Substance P	2009
Association of stress with symptoms of atopic dermatitis. Acta dermato-venereologica, 2010, Volume: 90, Issue:6 Topics: Adolescent; Adult; Anxiety; Biopsy; Case-Control Studies; Child; Depression; Dermatitis, Atopic; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nerve Growth Factor; Neuropeptide Y; Prognosis; Pruritus; Quality of Life; Receptors, Corticotropin-Releasing Hormone; Republic of Korea; Severity of Illness Index; Skin; Stress, Psychological; Substance P; Surveys and Questionnaires; Young Adult	2010
Involvement of midbrain tectum neurokinin-mediated mechanisms in fear and anxiety. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2012, Volume: 45, Issue:4 Topics: Animals; Anxiety; Avoidance Learning; Electric Stimulation; Escape Reaction; Fear; Inferior Colliculi; Male; Neurokinin A; Neurokinin-1 Receptor Antagonists; Periaqueductal Gray; Rats; Rats, Wistar; Substance P; Vocalization, Animal	2012
Sensitization of hypervigilance effects of cocaine can be induced by NK3 receptor activation in marmoset monkeys. Drug and alcohol dependence, 2013, Feb-01, Volume: 128, Issue:1-2 Topics: Animals; Anxiety; Behavior, Animal; Callithrix; Cocaine; Dopamine Uptake Inhibitors; Motor Activity; Peptide Fragments; Receptors, Neurokinin-3; Substance P	2013
The role of lateral septal NK1 receptors in mediating anxiogenic effects induced by intracerebroventricular injection of substance P. Behavioural brain research, 2002, Aug-21, Volume: 134, Issue:1-2 Topics: Animals; Anxiety; Dipeptides; Grooming; Indoles; Injections, Intraventricular; Male; Neurokinin-1 Receptor Antagonists; Posture; Rats; Rats, Wistar; Receptors, Neurokinin-1; Septum of Brain; Substance P	2002
Diminished anxiety- and depression-related behaviors in mice with selective deletion of the Tac1 gene. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Nov-15, Volume: 22, Issue:22 Topics: Animals; Anxiety; Behavior, Animal; Depression; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Motor Activity; Neurokinin A; Neurosurgical Procedures; Olfactory Bulb; Smell; Social Behavior; Spatial Behavior; Stress, Physiological; Substance P	2002
Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Sep-10, Volume: 23, Issue:23 Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Psychological; Crosses, Genetic; Drug Administration Routes; Illicit Drugs; Immunotoxins; Male; Maze Learning; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Narcotics; Neurons; Nucleus Accumbens; Receptors, Neurokinin-1; Reward; Ribosome Inactivating Proteins, Type 1; Saporins; Spatial Behavior; Substance P	2003
Involvement of tachykinin NK1 receptor in the behavioral and immunological responses to swimming stress in mice. Neuropeptides, 2003, Volume: 37, Issue:5 Topics: Animals; Anxiety; Behavior, Animal; Dipeptides; Indoles; Injections, Intraventricular; Leukocyte Count; Maze Learning; Mice; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Stress, Physiological; Substance P; Swimming	2003
Substance P in the medial amygdala: emotional stress-sensitive release and modulation of anxiety-related behavior in rats. Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-23, Volume: 101, Issue:12 Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Male; Microinjections; Rats; Rats, Sprague-Dawley; Stress, Physiological; Substance P	2004
Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. Journal of psychiatry & neuroscience : JPN, 2004, Volume: 29, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Antiemetics; Anxiety; Aprepitant; Autoreceptors; Depressive Disorder, Major; Electrophysiology; Hippocampus; Locus Coeruleus; Mice; Mice, Mutant Strains; Morpholines; Neurokinin-1 Receptor Antagonists; Norepinephrine; Phenylephrine; Photomicrography; Raphe Nuclei; Receptors, Neurokinin-1; Serotonin; Substance P	2004
Behavioral and immunological effects of substance P in female and male mice. Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:1 Topics: Animals; Anxiety; Behavior, Animal; Female; Grooming; Immunity; Injections, Intraventricular; Leukocyte Count; Lymphocyte Count; Macrophage Activation; Macrophages; Male; Mice; Motor Activity; Neutrophils; Nitric Oxide; Sex Characteristics; Substance P	2004
A remote and highly conserved enhancer supports amygdala specific expression of the gene encoding the anxiogenic neuropeptide substance-P. Molecular psychiatry, 2006, Volume: 11, Issue:4 Topics: Amygdala; Animals; Anxiety; Base Sequence; Cells, Cultured; Chickens; Computational Biology; Conserved Sequence; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Developmental; Homeodomain Proteins; Humans; Mice; Mice, Transgenic; Molecular Sequence Data; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Protein Precursors; Sequence Homology, Nucleic Acid; Substance P; Tachykinins; Transcription Factors	2006
Involvement of NK1 receptors in metabolic stress markers after the central administration of substance P. Behavioural brain research, 2007, Aug-06, Volume: 181, Issue:2 Topics: Analysis of Variance; Animals; Anxiety; Biomarkers; Blood Glucose; Corticosterone; Energy Metabolism; Fatty Acids, Nonesterified; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Neurokinin-1; Signal Transduction; Stress, Physiological; Substance P	2007
Modulation of anxiety in rats evaluated in the elevated T-maze: evidence of the relationship between substance P and diazepam. Behavioural brain research, 2008, Feb-11, Volume: 187, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Diazepam; Dipeptides; Fear; Indoles; Injections, Intraperitoneal; Injections, Intraventricular; Male; Memory; Neurokinin-1 Receptor Antagonists; Rats; Rats, Wistar; Substance P	2008
Anxiolytic-like effects of substance P administration into the dorsal, but not ventral, hippocampus and its influence on serotonin. Peptides, 2008, Volume: 29, Issue:7 Topics: Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Male; Maze Learning; Microdialysis; Microinjections; Rats; Rats, Wistar; Serotonin; Substance P	2008
Beta-endorphin, but not substance-P, is increased by acute stress in humans. Psychoneuroendocrinology, 1995, Volume: 20, Issue:1 Topics: Adult; Anxiety; Arousal; Aviation; beta-Endorphin; Humans; Internal-External Control; Male; Personality Inventory; Stress, Psychological; Substance P	1995
Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice. European journal of pharmacology, 1996, Sep-05, Volume: 311, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzamides; Dipeptides; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Mice; Motor Activity; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Postural Balance; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P	1996
Anxiolytic-like action of neurokinin substance P administered systemically or into the nucleus basalis magnocellularis region. European journal of pharmacology, 1998, Aug-07, Volume: 354, Issue:2-3 Topics: Animals; Anti-Anxiety Agents; Anxiety; Fear; Male; Maze Learning; Rats; Rats, Wistar; Social Behavior; Substance P; Substantia Innominata	1998
[Changes in levels of substance P, peptide suppressing diazepam binding, and neuropeptide Y in the brain of high- and low-anxiety inbred rats during stress]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 128, Issue:9 Topics: Animals; Anxiety; Brain; Diazepam; Hippocampus; Hypothalamus; Mesencephalon; Neuropeptide Y; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, GABA-A; Stress, Psychological; Substance P	1999
Anxiogenic-like effect induced by substance P injected into the lateral septal nucleus. Neuroreport, 1999, Nov-08, Volume: 10, Issue:16 Topics: Animals; Anxiety; Injections; Injections, Intraventricular; Lateral Ventricles; Male; Motor Activity; Rats; Rats, Wistar; Septal Nuclei; Substance P	1999
Tachykinin NK(3)receptor involvement in anxiety. Neuropeptides, 1999, Volume: 33, Issue:2 Topics: Animals; Anxiety; Cerebral Ventricles; Injections, Intraventricular; Male; Maze Learning; Mice; Neurokinin A; Neurokinin B; Peptide Fragments; Piperidines; Receptors, Neurokinin-3; Substance P; Tachykinins	1999
Anxiogenic effects of substance P and its 7-11 C terminal, but not the 1-7 N terminal, injected into the dorsal periaqueductal gray. Peptides, 1999, Volume: 20, Issue:12 Topics: Animals; Anxiety; Behavior, Animal; Male; Peptide Fragments; Periaqueductal Gray; Rats; Rats, Wistar; Substance P	1999
Anxiolytic-like effects in rats produced by ventral pallidal injection of both N- and C-terminal fragments of substance P. Neuroscience letters, 2000, Mar-31, Volume: 283, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anxiety; Basal Nucleus of Meynert; Globus Pallidus; Male; Maze Learning; Protein Structure, Tertiary; Rats; Rats, Wistar; Substance P	2000
NKP608: a selective NK-1 receptor antagonist with anxiolytic-like effects in the social interaction and social exploration test in rats. Regulatory peptides, 2000, Dec-22, Volume: 96, Issue:1-2 Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cattle; Dose-Response Relationship, Drug; Gerbillinae; Hindlimb; Humans; Inhibitory Concentration 50; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Protein Binding; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Social Behavior; Species Specificity; Substance P; Tumor Cells, Cultured	2000
Differences in genetic predisposition to high anxiety in two inbred rat strains: role of substance P, diazepam binding inhibitor fragment and neuropeptide Y. Psychopharmacology, 2001, Volume: 154, Issue:4 Topics: Animals; Anxiety; Behavior, Animal; Genetic Predisposition to Disease; Hippocampus; Hypothalamus; Male; Mesencephalon; Neuropeptide Y; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Species Specificity; Stress, Physiological; Substance P	2001
Cellular basis for the effects of substance P in the periaqueductal gray and dorsal raphe nucleus. The Journal of comparative neurology, 2002, May-20, Volume: 447, Issue:1 Topics: Animals; Anxiety; Dendrites; Enkephalins; Glutamic Acid; Immunohistochemistry; Male; Microscopy, Electron; Neurons; Pain; Periaqueductal Gray; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Serotonin; Substance P; Synaptic Transmission; Tryptophan Hydroxylase	2002
Anxiolytic-like effects of substance P fragment (SP(1-7)) in non-human primates (Callithrix penicillata). Peptides, 2002, Volume: 23, Issue:5 Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Callithrix; Exploratory Behavior; Fear; Female; Male; Maze Learning; Peptide Fragments; Predatory Behavior; Substance P	2002
The substance P (NK1) receptor antagonist (+/-)-CP-96,345 causes sedation and motor impairment in Swiss albino mice in the black-and-white box behavioral paradigm. Neuroscience letters, 1992, Aug-31, Volume: 143, Issue:1-2 Topics: Animals; Anxiety; Biphenyl Compounds; Depression, Chemical; Exploratory Behavior; Hypnotics and Sedatives; Male; Mice; Motor Activity; Naloxone; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Opioid; Rotation; Substance P	1992
Comparative behavioral and neurochemical studies with striatal kainic acid- or quinolinic acid-lesioned rats. Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:2 Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Body Weight; Brain Chemistry; Corpus Striatum; Exploratory Behavior; gamma-Aminobutyric Acid; Kainic Acid; Male; Motor Activity; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Rotation; Substance P	1991