Page last updated: 2024-08-23

substance p and Angiogenesis, Pathologic

substance p has been researched along with Angiogenesis, Pathologic in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (31.43)18.2507
2000's7 (20.00)29.6817
2010's15 (42.86)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Afshari, AR; AlAlikhan, A; Ghahremanloo, A; Hashemy, SI; Javid, H; Momen Razmgah, M1
Ge, W; He, M; Lin, Y; Pang, J; Sun, H; Zheng, G1
Barry, CM; Haberberger, RV; Ji, E; Kyloh, M; Sharma, H; Spencer, NJ; Vilimas, P; Yap, P1
Rees, JD; Scott, A; Stride, M1
Berger, M; de Agustín Asencio, JC; Garnier, A; Ilmer, M; Kappler, R; Muñoz, M; Neth, O; Salinas-Martín, MV; von Schweinitz, D1
Coveñas, R; Muñoz, M2
Gupta, K; Gupta, P; Li, Y; Luk, K; Nguyen, J; Robiner, S; Saavedra, R; Soto, W; Vang, D; Vincent, L1
Daschil, N; Humpel, C; Hutter-Paier, B; Kniewallner, KM; Marksteiner, J; Obermair, GJ; Windisch, M1
Covenas, R; Esteban, F; Munoz, M; Redondo, M1
Aydemir, EA; Fışkın, K; İmir, N; Koçak, O; Kuruoğlu, A; Şimşek, E1
Azuero-Holguin, MM; Caviedes-Bucheli, J; Gomez-Sosa, JF; Munoz, HR; Ormeño-Gomez, M; Pinto-Pascual, V1
Freeman, TA; Isaza, JE; Kurtz, SM; Lanman, TH; Steinbeck, MJ; Veruva, SY1
Bowe, C; Koon, HW; Moss, A; Moyer, MP; Pothoulakis, C; Xu, H; Zhao, D1
Coveñas, R; Muñoz, M; Rosso, M1
Andersson, G; Backman, LJ; Danielson, P; Forsgren, S; Lorentzon, R; Scott, A1
Channappanavar, R; Suvas, S; Twardy, BS1
Jung, Y; Kim, BS; Kim, JH; Kim, SH1
Cruwys, SC; Hood, VC; Kidd, BL; Seegers, HC; Walsh, DA1
Burdick, M; Eibl, G; Fan, RS; Guha, S; Hines, OJ; Kisfalvi, K; Reber, H; Rozengurt, E; Strieter, R1
Ha, HS; Kim, JC; Kim, MK; Lee, JK; Park, AJ; Park, JH; Song, YS1
Gill, SE; Massena de Camin, S; McWilliams, DF; Suri, S; Walsh, DA; Wilson, D1
Ackermann, PW; Bring, DK; Dahl, J; Li, J; Renström, P1
Amerini, S; Geppetti, P; Granger, HJ; Ledda, F; Maggi, CA; Masini, E; Morbidelli, L; Ziche, M1
Fan, TP; Hori, Y; Hu, DE1
Fan, TP; Gresham, GA; Guard, S; Hu, DE; Watling, KJ1
Kido, MA; Kiyoshima, T; Kondo, T; Tanaka, T; Yamaza, T1
Baluk, P; Bowden, JJ; Lefevre, PM; Lindsey, JR; McDonald, DM; Schoeb, TR1
Auer, B; Kähler, CM; Reinisch, N; Schratzberger, P; Sitte, B; Wiedermann, CJ1
Blake, DR; Fan, TP; Hu, DE; Mapp, PI; Polak, JM; Walsh, DA1
Baluk, P; Bowden, JJ; Bunnett, NW; McDonald, DM1
Baluk, P; Bowden, JJ; Lefevre, PM; McDonald, DM1
Baluk, P; Lindsey, JR; McDonald, DM; Murphy, TJ; Thurston, G1
Fearon, U; Veale, DJ1
Alessandri, G; Geppetti, P; Maggi, CA; Morbidelli, L; Pacini, M; Ziche, M1

Reviews

8 review(s) available for substance p and Angiogenesis, Pathologic

ArticleYear
Tendons--time to revisit inflammation.
    British journal of sports medicine, 2014, Volume: 48, Issue:21

    Topics: Anti-Inflammatory Agents; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Musculoskeletal Pain; Neovascularization, Pathologic; Substance P; Tendinopathy; Tendons; Tumor Necrosis Factor-alpha

2014
Cancer progression and substance P.
    Histology and histopathology, 2014, Volume: 29, Issue:7

    Topics: Animals; Disease Progression; Humans; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Substance P

2014
Involvement of substance P and the NK-1 receptor in pancreatic cancer.
    World journal of gastroenterology, 2014, Mar-07, Volume: 20, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Movement; Cell Proliferation; Humans; Molecular Targeted Therapy; Neoplasm Invasiveness; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Pancreatic Neoplasms; Receptors, Neurokinin-1; Signal Transduction; Substance P; Treatment Outcome

2014
The substance P/NK-1 receptor system: NK-1 receptor antagonists as anti-cancer drugs.
    Journal of biosciences, 2015, Volume: 40, Issue:2

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Apoptosis; Aprepitant; Cell Movement; Cell Proliferation; Emotions; Humans; Inflammation; Morpholines; Neoplasms; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Substance P

2015
Angiogenic mechanisms of human dental pulp and their relationship with substance P expression in response to occlusal trauma.
    International endodontic journal, 2017, Volume: 50, Issue:4

    Topics: Dental Occlusion, Traumatic; Dental Pulp; Humans; Neovascularization, Pathologic; Substance P

2017
A new frontier in the treatment of cancer: NK-1 receptor antagonists.
    Current medicinal chemistry, 2010, Volume: 17, Issue:6

    Topics: Antineoplastic Agents; Humans; Neoplasms; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Peptides; Receptors, Neurokinin-1; Substance P

2010
Neurogenic inflammation. A model for studying efferent actions of sensory nerves.
    Advances in experimental medicine and biology, 1996, Volume: 410

    Topics: Afferent Pathways; Animals; Capillary Leak Syndrome; Capsaicin; Carotid Body; Efferent Pathways; Endothelium, Vascular; Guinea Pigs; Inflammation; Mycoplasma Infections; Neovascularization, Pathologic; Neurons, Afferent; Rats; Receptors, Neurokinin-1; Respiratory System; Respiratory Tract Diseases; Respiratory Tract Infections; Substance P; Venules

1996
Pathogenesis of psoriatic arthritis.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:4

    Topics: Arthritis, Psoriatic; Autoimmune Diseases; Endothelium, Vascular; Epidermis; Humans; Immunogenetics; Joints; Neovascularization, Pathologic; Streptococcal Infections; Stress, Mechanical; Stress, Psychological; Substance P; T-Lymphocytes

2001

Other Studies

27 other study(ies) available for substance p and Angiogenesis, Pathologic

ArticleYear
The effect of substance P and its specific antagonist (aprepitant) on the expression of MMP-2, MMP-9, VEGF, and VEGFR in ovarian cancer cells.
    Molecular biology reports, 2022, Volume: 49, Issue:10

    Topics: Aprepitant; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Female; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neovascularization, Pathologic; Ovarian Neoplasms; Receptors, Neurokinin-1; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Substance P; Vascular Endothelial Growth Factor A

2022
Overexpression of TIMP3 inhibits discogenic pain by suppressing angiogenesis and the expression of substance P in nucleus pulposus.
    Molecular medicine reports, 2020, Volume: 21, Issue:3

    Topics: Adenoviridae; Animals; Back Pain; Genetic Vectors; Intervertebral Disc Degeneration; Male; Neovascularization, Pathologic; Nucleus Pulposus; Rats; Rats, Sprague-Dawley; Substance P; Tissue Inhibitor of Metalloproteinase-3; Transduction, Genetic; Up-Regulation

2020
Innervation Changes Induced by Inflammation in the Murine Vagina.
    Neuroscience, 2018, 02-21, Volume: 372

    Topics: Animals; Calcitonin Gene-Related Peptide; Edema; Female; Freund's Adjuvant; Inflammation; Mice, Inbred C57BL; Neovascularization, Pathologic; Nerve Fibers; Substance P; Time Factors; Vagina; Vasoactive Intestinal Peptide

2018
Hepatoblastoma cells express truncated neurokinin-1 receptor and can be growth inhibited by aprepitant in vitro and in vivo.
    Journal of hepatology, 2014, Volume: 60, Issue:5

    Topics: Animals; Apoptosis; Aprepitant; Cell Line, Tumor; Cell Proliferation; Child; Cytostatic Agents; Drug Synergism; Female; Gene Expression; Hep G2 Cells; Hepatoblastoma; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Morpholines; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Protein Isoforms; Receptors, Neurokinin-1; Substance P; Xenograft Model Antitumor Assays

2014
Morphine stimulates cancer progression and mast cell activation and impairs survival in transgenic mice with breast cancer.
    British journal of anaesthesia, 2014, Volume: 113 Suppl 1

    Topics: Analgesics, Opioid; Animals; Cytokines; Disease Progression; Female; Kaplan-Meier Estimate; Lymphangiogenesis; Mammary Neoplasms, Experimental; Mast Cells; Mice; Mice, Transgenic; Morphine; Neovascularization, Pathologic; Receptors, Opioid, mu; Substance P

2014
L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model.
    Neurobiology of aging, 2015, Volume: 36, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebral Cortex; Disease Models, Animal; Mice, Transgenic; Neovascularization, Pathologic; Plaque, Amyloid; RNA, Messenger; Substance P

2015
Dimethyl sulfoxide-caused changes in pro- and anti-angiogenic factor levels could contribute to an anti-angiogenic response in HeLa cells.
    Neuropeptides, 2015, Volume: 53

    Topics: Cell Proliferation; Cell Survival; Dimethyl Sulfoxide; HeLa Cells; Humans; Interferon-gamma; Neovascularization, Pathologic; Substance P; Trypan Blue; Vascular Endothelial Growth Factor A

2015
Periprosthetic UHMWPE Wear Debris Induces Inflammation, Vascularization, and Innervation After Total Disc Replacement in the Lumbar Spine.
    Clinical orthopaedics and related research, 2017, Volume: 475, Issue:5

    Topics: Adult; Biopsy; Cytokines; Device Removal; Discitis; Female; Humans; Immunohistochemistry; Inflammation Mediators; Intervertebral Disc; Intervertebral Disc Degeneration; Low Back Pain; Lumbar Vertebrae; Macrophages; Male; Middle Aged; Neovascularization, Pathologic; Pain Measurement; Pain, Postoperative; Polyethylenes; Prosthesis Design; Reoperation; Risk Factors; Stress, Mechanical; Substance P; Time Factors; Total Disc Replacement; Treatment Outcome; United States; Vascular Endothelial Growth Factor A; Young Adult

2017
Substance P-mediated expression of the pro-angiogenic factor CCN1 modulates the course of colitis.
    The American journal of pathology, 2008, Volume: 173, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Colitis, Ulcerative; Colon; Crohn Disease; Cysteine-Rich Protein 61; Dextran Sulfate; Endothelial Cells; Endothelium, Vascular; Humans; Immediate-Early Proteins; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Microcirculation; Neovascularization, Pathologic; Receptors, Neurokinin-1; Substance P

2008
Substance P accelerates hypercellularity and angiogenesis in tendon tissue and enhances paratendinitis in response to Achilles tendon overuse in a tendinopathy model.
    British journal of sports medicine, 2011, Volume: 45, Issue:13

    Topics: Achilles Tendon; Administration, Cutaneous; Animals; Cell Proliferation; Cumulative Trauma Disorders; Female; Neovascularization, Pathologic; Neurotransmitter Agents; Physical Conditioning, Animal; Rabbits; Random Allocation; Receptors, Neurokinin-1; Substance P; Tendinopathy

2011
Substance P in the corneal stroma regulates the severity of herpetic stromal keratitis lesions.
    Investigative ophthalmology & visual science, 2011, Nov-04, Volume: 52, Issue:12

    Topics: Analgesics; Animals; CD4-Positive T-Lymphocytes; Chemokine CCL3; Chemokine CXCL2; Corneal Stroma; Disease Models, Animal; Female; Herpesvirus 1, Human; Interleukin-6; Keratitis, Herpetic; Leukocyte Common Antigens; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Neutrophils; Receptors, Neurokinin-1; Severity of Illness Index; Substance P; Tubulin; Viral Load

2011
Stem cell recruitment and angiogenesis of neuropeptide substance P coupled with self-assembling peptide nanofiber in a mouse hind limb ischemia model.
    Biomaterials, 2013, Volume: 34, Issue:6

    Topics: Amino Acid Sequence; Animals; Hindlimb; In Situ Nick-End Labeling; Ischemia; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Molecular Sequence Data; Nanofibers; Neovascularization, Pathologic; Peptides; Substance P

2013
Enhancement of angiogenesis by endogenous substance P release and neurokinin-1 receptors during neurogenic inflammation.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:1

    Topics: Animals; Endothelium; Knee Joint; Macrophages; Male; Neovascularization, Pathologic; Neurogenic Inflammation; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P

2003
Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1,D-Trp5,7,9,Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer.
    Cancer research, 2005, Apr-01, Volume: 65, Issue:7

    Topics: Animals; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Growth Processes; Cornea; DNA, Neoplasm; Humans; Interleukin-8; Ki-67 Antigen; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Neovascularization, Physiologic; Pancreatic Neoplasms; Rats; Receptors, G-Protein-Coupled; Substance P; Xenograft Model Antitumor Assays

2005
Endothelial progenitor cells in pterygium pathogenesis.
    Eye (London, England), 2007, Volume: 21, Issue:9

    Topics: Age Distribution; Aged; Chemotactic Factors; Endothelial Cells; Endothelium, Vascular; Female; Humans; Hypoxia; Inflammation Mediators; Leukocyte Count; Male; Middle Aged; Neovascularization, Pathologic; Pterygium; Recurrence; Sex Distribution; Stem Cell Factor; Stem Cells; Substance P; Vascular Endothelial Growth Factor A

2007
Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis.
    Annals of the rheumatic diseases, 2007, Volume: 66, Issue:11

    Topics: Aged; Aged, 80 and over; Calcitonin Gene-Related Peptide; Cartilage, Articular; Female; Humans; Knee Joint; Male; Neovascularization, Pathologic; Nerve Fibers; Osteoarthritis, Knee; Peripheral Nervous System; Severity of Illness Index; Substance P; Ubiquitin Thiolesterase

2007
Intermittent pneumatic compression enhances neurovascular ingrowth and tissue proliferation during connective tissue healing: a study in the rat.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2007, Volume: 25, Issue:9

    Topics: Achilles Tendon; Animals; Biomarkers; Calcitonin Gene-Related Peptide; Cell Proliferation; Connective Tissue; Fibroblasts; Intermittent Pneumatic Compression Devices; Male; Neovascularization, Pathologic; Nerve Fibers; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Rupture; Substance P; Wound Healing

2007
Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:5

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Cell Movement; Cells, Cultured; Cyclic GMP; DNA; Endothelium, Vascular; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Platelet Aggregation; Rabbits; Substance P

1994
Interleukin-8 stimulates angiogenesis in rats.
    Inflammation, 1993, Volume: 17, Issue:2

    Topics: Animals; Bradykinin; Drug Synergism; Interleukin-1; Interleukin-8; Male; Neovascularization, Pathologic; Rats; Rats, Wistar; Substance P; Surgical Sponges; Tumor Necrosis Factor-alpha

1993
Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Inflammation; Interleukin-1; Male; Neovascularization, Pathologic; Neurokinin-1 Receptor Antagonists; Platelet Activating Factor; Prostaglandins; Rats; Rats, Wistar; Receptors, Interleukin-1; Receptors, Neurokinin-1; Regional Blood Flow; Substance P; Xenon Radioisotopes

1993
An immunohistochemical and monastral blue-vascular labelling study on the involvement of capsaicin-sensitive sensory innervation of the junctional epithelium in neurogenic plasma extravasation in the rat gingiva.
    Archives of oral biology, 1995, Volume: 40, Issue:10

    Topics: Animals; Calcitonin Gene-Related Peptide; Capillaries; Capillary Permeability; Capsaicin; Coloring Agents; Epithelial Attachment; Gingiva; Gingivitis; Hyperplasia; Immunohistochemistry; Indoles; Male; Neovascularization, Pathologic; Neurons, Afferent; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Substance P; Venules

1995
Sensory denervation by neonatal capsaicin treatment exacerbates Mycoplasma pulmonis infection in rat airways.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Animals; Animals, Newborn; Capsaicin; Denervation; Epithelium; Inflammation; Lung Diseases; Male; Mucous Membrane; Mycoplasma Infections; Neovascularization, Pathologic; Nerve Fibers; Neurons, Afferent; Rats; Rats, Inbred F344; Substance P; Trachea

1996
Induction of endothelial cell differentiation into capillary-like structures by substance P.
    European journal of pharmacology, 1996, Mar-18, Volume: 298, Issue:3

    Topics: Basement Membrane; Capillaries; Cell Differentiation; Endothelium, Vascular; Humans; In Vitro Techniques; Neovascularization, Pathologic; Substance P; Umbilical Veins

1996
Innervation and neurokinin receptors during angiogenesis in the rat sponge granuloma.
    The Histochemical journal, 1996, Volume: 28, Issue:11

    Topics: Animals; Binding Sites; Dermatitis; Granuloma; Microcirculation; Neovascularization, Pathologic; Porifera; Rats; Receptors, Neurokinin-1; Skin; Substance P

1996
Upregulation of substance P receptors in angiogenesis associated with chronic airway inflammation in rats.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: Animals; Capillaries; Coloring Agents; Endosomes; Endothelium, Vascular; Indoles; Inflammation; Male; Mucous Membrane; Mycoplasma Infections; Neovascularization, Pathologic; Nerve Fibers; Organometallic Compounds; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Substance P; Trachea; Up-Regulation; Venules

1997
Angiogenesis in mice with chronic airway inflammation: strain-dependent differences.
    The American journal of pathology, 1998, Volume: 153, Issue:4

    Topics: Animals; Capillary Permeability; Cell Count; Chronic Disease; Endothelium, Vascular; Evans Blue; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neovascularization, Pathologic; Pneumonia, Mycoplasma; Silver Staining; Species Specificity; Specific Pathogen-Free Organisms; Substance P; Trachea; Tracheitis; Wheat Germ Agglutinins

1998
Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells.
    Microvascular research, 1990, Volume: 40, Issue:2

    Topics: Animals; Cell Division; Cell Line; Endothelium, Vascular; Neovascularization, Pathologic; Rabbits; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Tachykinins

1990