Page last updated: 2024-08-23

substance p and Alzheimer Disease

substance p has been researched along with Alzheimer Disease in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199022 (40.00)18.7374
1990's24 (43.64)18.2507
2000's4 (7.27)29.6817
2010's4 (7.27)24.3611
2020's1 (1.82)2.80

Authors

AuthorsStudies
Bowers, MT; Buratto, SK; Ganguly, P; Jhatro, MJ; Jin, Y; Liu, X; Shea, JE1
de Levy, GS; Fink, G; Gordon, A; Harmar, AJ; Maloney, AF; Rosie, R; Sheward, J; Simpson, J; Yates, CM1
Calissano, P; Campolongo, P; Ciotti, MT; Florenzano, F; Marolda, R; Nori, SL; Palmery, M; Possenti, R; Ratano, P; Rinaldi, AM; Severini, C; Zona, C1
Daschil, N; Humpel, C; Hutter-Paier, B; Kniewallner, KM; Marksteiner, J; Obermair, GJ; Windisch, M1
Almqvist, EG; Andreasson, U; Blennow, K; Johansson, JO; Johansson, P; Svensson, J; Wallin, A; Zetterberg, H1
Calissano, P; Petrella, C; Severini, C1
Ahmed, MM; Arif, M; Chikuma, T; Kato, T; Nakazato, M; Smith, MA1
Fukuoka, Y; Hatakeyama, A; Hatakeyama, R; Sasaki, H; Sato, A1
Arregui, A; Blessed, G; Cross, AJ; Crow, TJ; Dimaline, R; Dockray, GJ; Perry, EK; Perry, RH; Tomlinson, BE1
Crystal, HA; Davies, P1
Perry, EK; Perry, RH1
Bouras, C; Constantinidis, J; Richard, J1
Shibuya, H1
Adrian, TE; Corsellis, JA; Cross, AJ; Crow, TJ; Ferrier, IN; Johnson, JA; Lee, YC; McGregor, GP; O'Shaughnessy, D; Roberts, GW1
Beal, MF; Landis, DM; Marshall, PE; Martin, JB; Sagar, SM1
Joyce, JN; Rioux, L1
Cadman, ED; Lee, CM; Witte, DG1
Ang, LC; Shul, DD1
David, TP; Waters, SM1
Frank, A; Hernanz, A; Tato, RE1
Doucette, T; Duong, T; Jacobs, RW; Scheibel, AB; Zidenberg, NA1
Armstrong, DM; Benzing, WC; Brady, DR; Ikonomovic, MD; Mufson, EJ1
Armstrong, DM; Benzing, WC; Brady, DR; Mufson, EJ1
Fujiwara, T; Iwamoto, Y; Kato, T; Okamiya, K; Shinoda, M; Toide, K1
Nabeshima, T; Nitta, A1
Davis, TP; Waters, SM1
Brenner, JW; Gokden, M; Lorenz, RG; Roth, KA; Selznick, LA1
Nag, S; Tang, F1
Chen, H; Helme, RD; Khalil, Z1
El-Agnaf, OM; Fitzpatrick, G; Glass, WK; Guthrie, DJ; Irvine, GB1
Jellinger, KA; Rösler, N; Wichart, I2
Bouras, C; Charnay, Y; Constantinidis, J; Golaz, J; Hof, PR; Vallet, PG1
Beyreuther, K; Koo, EH; Price, DL; Sisodia, SS; Unterbeck, A1
Goto, S; Hirano, A; Matsumoto, S1
Alufuzoff, I; Nordberg, A; Sakurada, T; Winblad, B1
Armstrong, DM; Benzing, WC; Jennes, L; Mufson, EJ1
Kowall, NW; Quigley, BJ1
Delaère, P; Duyckaerts, C; Hauw, JJ; He, Y; Piette, F1
Marx, J1
Barker, R1
Armstrong, DM; Terry, RD1
Cramer, H; Kuntzmann, F; Rissler, K; Schaudt, D; Strubel, D; Warter, JM1
Dawbarn, D; Dockray, G; Emson, P; Mountjoy, C; Rossor, M; Roth, M1
Weber, M1
Bouras, C; Constantinidis, J; de St-Hilaire, S; Dobrinov, H; Vallet, PG1
Armstrong, DM; Bruce, G; Hersh, LB; Terry, RD1
Bouras, C; Constantinidis, J; de St Hilaire-Kafi, S1
Beal, MF; Mazurek, MF1
Beal, MF; Kowall, NW; Mazurek, MF1
Cramer, H; Ernst, A; Kuntzmann, F; Schoenenberger, GA; Strubel, D1
Harigaya, Y; Hirai, S; Okamoto, K; Shoji, M; Yamaguchi, H1
Beal, MF; Clevens, RA1
Armstrong, DM; Benzing, WC; Evans, J; Hansen, LA; Shields, D; Terry, RD1
Eng, LF; Forno, LS; Grafe, MR1

Reviews

9 review(s) available for substance p and Alzheimer Disease

ArticleYear
Substance P and Alzheimer's Disease: Emerging Novel Roles.
    Current Alzheimer research, 2016, Volume: 13, Issue:9

    Topics: Alzheimer Disease; Animals; Brain; Humans; Potassium Channels; Substance P

2016
Putative peptide neurotransmitters in human neuropathology: a review of topography and clinical implications.
    Clinical neuropathology, 1983, Volume: 2, Issue:2

    Topics: Alzheimer Disease; Brain Mapping; Central Nervous System Diseases; Cholecystokinin; Enkephalins; Humans; Huntington Disease; Limbic System; Nerve Tissue Proteins; Neurotransmitter Agents; Parkinson Disease; Schizophrenia; Substance P; Substance-Related Disorders

1983
[Neuropeptides and mental disorders].
    Nihon rinsho. Japanese journal of clinical medicine, 1983, Volume: 41, Issue:5

    Topics: Aged; Alzheimer Disease; Animals; Brain; Cholecystokinin; Depressive Disorder; Endorphins; Female; Humans; Male; Mental Disorders; Middle Aged; Nerve Tissue Proteins; Neurotransmitter Agents; Schizophrenia; Substance P; Vasopressins

1983
Implications of neuropeptides in neurological diseases.
    Peptides, 1984, Volume: 5 Suppl 1

    Topics: Alzheimer Disease; Animals; Brain; Cholecystokinin; Choline O-Acetyltransferase; Endorphins; Epilepsy; Forecasting; Histocytochemistry; Humans; Huntington Disease; Migraine Disorders; Nerve Tissue Proteins; Nervous System Diseases; Pain; Parkinson Disease; Radioimmunoassay; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Tissue Distribution; Vasopressins

1984
Substance P and neurodegenerative disorders. A speculative review.
    Neuropeptides, 1991, Volume: 20, Issue:2

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Autoimmunity; Central Nervous System Diseases; Humans; Parkinson Disease; Substance P

1991
Postmortem studies of peptides in Alzheimer's disease and Huntington's disease.
    Research publications - Association for Research in Nervous and Mental Disease, 1986, Volume: 64

    Topics: Alzheimer Disease; Basal Ganglia; Brain; Brain Chemistry; Cerebral Cortex; Choline O-Acetyltransferase; Enkephalin, Methionine; FMRFamide; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Huntington Disease; Nerve Tissue Proteins; Neurofibrils; Neuropeptide Y; Neurotensin; Oligopeptides; Peptides; Substance P; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide

1986
Alzheimer's disease and the cytoskeleton.
    Biochimie, 1986, Volume: 68, Issue:4

    Topics: Acetylcholine; Acetylcholinesterase; Aged; Alzheimer Disease; Amino Acid Sequence; Amyloid; Cerebral Cortex; Choline O-Acetyltransferase; Cytoskeletal Proteins; Cytoskeleton; Hippocampus; Humans; Nerve Tissue Proteins; Neurofibrils; Neuroglia; Neurons; Peptide Fragments; Slow Virus Diseases; Somatostatin; Substance P

1986
Neuropeptides in Alzheimer's disease: a review and morphological results.
    Progress in neuro-psychopharmacology & biological psychiatry, 1986, Volume: 10, Issue:3-5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Cholecystokinin; Choline O-Acetyltransferase; Humans; Middle Aged; Neuropeptide Y; Neuropeptides; Somatostatin; Substance P; Vasoactive Intestinal Peptide

1986
Neuropeptides in Alzheimer's disease.
    Journal of neural transmission. Supplementum, 1987, Volume: 24

    Topics: Alzheimer Disease; Brain Chemistry; Humans; Neuropeptide Y; Neuropeptides; Somatostatin; Substance P

1987

Other Studies

46 other study(ies) available for substance p and Alzheimer Disease

ArticleYear
Tachykinin Neuropeptides and Amyloid β (25-35) Assembly: Friend or Foe?
    Journal of the American Chemical Society, 2022, 08-17, Volume: 144, Issue:32

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Humans; Kassinin; Peptide Fragments; Substance P; Tachykinins

2022
Thyrotropin-releasing hormone, luteinizing hormone-releasing hormone and substance P immuno-reactivity in post-mortem brain from cases of Alzheimer-type dementia and Down's syndrome.
    Brain research, 1983, Jan-03, Volume: 258, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cadaver; Central Nervous System; Down Syndrome; Female; Gonadotropin-Releasing Hormone; Humans; Immunohistochemistry; Male; Middle Aged; Substance P; Thyrotropin-Releasing Hormone

1983
Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; Cognition; Cognition Disorders; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Kv1.4 Potassium Channel; Male; Maze Learning; Peptide Fragments; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Substance P

2013
L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model.
    Neurobiology of aging, 2015, Volume: 36, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebral Cortex; Disease Models, Animal; Mice, Transgenic; Neovascularization, Pathologic; Plaque, Amyloid; RNA, Messenger; Substance P

2015
Cerebrospinal fluid substance P concentrations are elevated in patients with Alzheimer's disease.
    Neuroscience letters, 2015, Nov-16, Volume: 609

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Case-Control Studies; Female; Humans; Male; Neurotensin; Orexins; Peptide Fragments; Substance P

2015
Effects of memantine on soluble Alphabeta(25-35)-induced changes in peptidergic and glial cells in Alzheimer's disease model rat brain regions.
    Neuroscience, 2009, Dec-15, Volume: 164, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biomarkers; Brain; CD11 Antigens; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Male; Memantine; Nerve Degeneration; Neuroglia; Neuropeptides; Nitric Oxide Synthase Type II; Oxidative Stress; Peptide Fragments; Peptide Hydrolases; Rats; Rats, Wistar; Somatostatin; Substance P

2009
[Therapy for geriatric syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2006, Mar-10, Volume: 95, Issue:3

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Humans; Lung Diseases, Interstitial; Lung Neoplasms; Mental Disorders; Nutritional Support; Pneumonia, Aspiration; Prognosis; Quality of Life; Substance P; Syndrome

2006
Neurochemical activities in human temporal lobe related to aging and Alzheimer-type changes.
    Neurobiology of aging, 1981,Winter, Volume: 2, Issue:4

    Topics: Aged; Aging; Alzheimer Disease; Cholecystokinin; Choline O-Acetyltransferase; Cognition; Dementia; Dopamine beta-Hydroxylase; Glutamate Decarboxylase; Humans; Middle Aged; Somatostatin; Substance P; Temporal Lobe; Vasoactive Intestinal Peptide

1981
Cortical substance P-like immunoreactivity in cases of Alzheimer's disease and senile dementia of the Alzheimer type.
    Journal of neurochemistry, 1982, Volume: 38, Issue:6

    Topics: Adult; Aged; Alzheimer Disease; Brain Chemistry; Cerebral Cortex; Choline O-Acetyltransferase; Dementia; Humans; Middle Aged; Reference Values; Somatostatin; Substance P; Tissue Distribution

1982
Neurotransmitter and neuropeptide systems in Alzheimer-type dementia.
    Experimental brain research, 1982, Volume: Suppl 5

    Topics: Aged; Alzheimer Disease; Amino Acids; Brain; Cholecystokinin; Choline O-Acetyltransferase; Dementia; Dopamine beta-Hydroxylase; Glutamate Decarboxylase; Humans; Middle Aged; Neurotransmitter Agents; Peptide Fragments; Sincalide; Somatostatin; Substance P

1982
Neuropeptides in Alzheimer type dementia.
    Journal of the neurological sciences, 1983, Volume: 62, Issue:1-3

    Topics: Aged; Alzheimer Disease; Brain; Brain Chemistry; Cholecystokinin; Choline O-Acetyltransferase; Female; Humans; Male; Nerve Tissue Proteins; Neurotensin; Reference Values; Somatostatin; Substance P; Tissue Distribution; Vasoactive Intestinal Peptide

1983
Substance P receptors are differentially affected in Parkinson's and Alzheimer's disease.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Basal Ganglia; Female; Globus Pallidus; Humans; Iodine Radioisotopes; Male; Middle Aged; Neostriatum; Parkinson Disease; Receptors, Neurokinin-1; Substance P; Succinimides

1993
Regulation of the release of interleukin-6 from human astrocytoma cells.
    Journal of neurochemistry, 1994, Volume: 63, Issue:3

    Topics: Adenylyl Cyclases; Alzheimer Disease; Astrocytoma; Calcium; Cycloheximide; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Histamine; Humans; Indomethacin; Inositol Phosphates; Interleukin-1; Interleukin-6; Kinetics; Protein Kinase C; Substance P; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Peptidergic neurons of subcortical white matter in aging and Alzheimer's brain.
    Brain research, 1995, Mar-20, Volume: 674, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cholecystokinin; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neurons; Neuropeptide Y; Neuropeptides; Somatostatin; Substance P; Visual Cortex

1995
Alterations of substance P metabolism and neuropeptidases in Alzheimer's disease.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cadaver; Caudate Nucleus; Hippocampus; Humans; Metalloendopeptidases; Middle Aged; Neprilysin; Substance P; Temporal Lobe

1995
Tau protein concentrations in cerebrospinal fluid of patients with dementia of the Alzheimer type.
    Journal of neurology, neurosurgery, and psychiatry, 1995, Volume: 59, Issue:3

    Topics: Aged; Alzheimer Disease; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Neuropeptide Y; Somatostatin; Substance P; tau Proteins

1995
Microtubule-associated proteins tau and amyloid P component in Alzheimer's disease.
    Brain research, 1993, Feb-12, Volume: 603, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Female; Humans; Immunoenzyme Techniques; Immunohistochemistry; Male; Middle Aged; Neurofibrillary Tangles; Serum Amyloid P-Component; Substance P; tau Proteins

1993
Evidence that transmitter-containing dystrophic neurites precede paired helical filament and Alz-50 formation within senile plaques in the amygdala of nondemented elderly and patients with Alzheimer's disease.
    The Journal of comparative neurology, 1993, Aug-08, Volume: 334, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amygdala; Amyloid beta-Peptides; Antigens; Choline O-Acetyltransferase; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neurites; Neurofibrillary Tangles; Neurotensin; Somatostatin; Substance P

1993
Evidence that transmitter-containing dystrophic neurites precede those containing paired helical filaments within senile plaques in the entorhinal cortex of nondemented elderly and Alzheimer's disease patients.
    Brain research, 1993, Aug-13, Volume: 619, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Female; Hippocampus; Humans; Immunohistochemistry; Intermediate Filaments; Male; Middle Aged; Neurites; Neurons; Substance P

1993
Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on neuropeptide metabolism in the rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3

    Topics: Administration, Oral; Alzheimer Disease; Animals; Arginine Vasopressin; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Neuropeptides; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Wistar; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P; Thyrotropin-Releasing Hormone

1996
[Experimental techniques for developing new drugs acting on dementia (10)--Alzheimer's disease animal model induced by beta-amyloid protein].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1996, Volume: 16, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Atrophy; Brain; Choline O-Acetyltransferase; Disease Models, Animal; Male; Microtubule Proteins; Neurotransmitter Agents; Rats; Rats, Wistar; Substance P

1996
Alterations of peptide metabolism and neuropeptidase activity in senile dementia of the Alzheimer's type.
    Annals of the New York Academy of Sciences, 1997, Apr-24, Volume: 814

    Topics: Aged; Alzheimer Disease; Amino Acid Sequence; Binding Sites; Brain; Humans; Molecular Sequence Data; Neuropeptides; Peptide Hydrolases; Somatostatin; Substance P

1997
Enzyme-based antigen localization and quantitation in cell and tissue samples (Midwestern assay).
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1997, Volume: 45, Issue:12

    Topics: Alzheimer Disease; Animals; Antibodies, Antinuclear; Brain Neoplasms; Bromodeoxyuridine; Cytoskeletal Proteins; DNA; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Humans; Ki-67 Antigen; Mice; Spinal Cord; Substance P; tau Proteins; Tumor Cells, Cultured

1997
Cholinergic lesions of the rat brain by ibotenic acid and 192 IgG-saporin: effects on somatostatin, substance P and neuropeptide Y levels in the cerebral cortex and the hippocampus.
    Neuroscience letters, 1998, Aug-14, Volume: 252, Issue:2

    Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Choline O-Acetyltransferase; Cholinergic Agents; Cholinergic Fibers; Excitatory Amino Acid Agonists; Hippocampus; Ibotenic Acid; Immunotoxins; Male; Maze Learning; N-Glycosyl Hydrolases; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Somatostatin; Substance P

1998
[The effect of endothelin and protein kinase C on the vasoactive mechanisms of beta A(4)25-35 at skin microvasculature].
    Zhonghua yi xue za zhi, 1997, Volume: 77, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Endothelin Receptor Antagonists; Endothelins; Indoles; Laser-Doppler Flowmetry; Male; Maleimides; Microcirculation; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; Skin; Substance P; Vasomotor System

1997
Comparative studies on peptides representing the so-called tachykinin-like region of the Alzheimer Abeta peptide [Abeta(25-35)].
    The Biochemical journal, 1998, Dec-01, Volume: 336 ( Pt 2)

    Topics: Alzheimer Disease; Amides; Amyloid beta-Peptides; Animals; Circular Dichroism; Eledoisin; Magnetic Resonance Spectroscopy; Neurokinin B; Norleucine; Peptide Fragments; Phenylalanine; Rats; Substance P; Tachykinins

1998
Ex vivo lumbar and post mortem ventricular cerebrospinal fluid substance P-immunoreactivity in Alzheimer's disease patients.
    Neuroscience letters, 2001, Feb-16, Volume: 299, Issue:1-2

    Topics: Age of Onset; Aged; Alzheimer Disease; Biomarkers; Brain; Female; Humans; Immunohistochemistry; Male; Postmortem Changes; Spinal Puncture; Substance P

2001
Clinical significance of neurobiochemical profiles in the lumbar cerebrospinal fluid of Alzheimer's disease patients.
    Journal of neural transmission (Vienna, Austria : 1996), 2001, Volume: 108, Issue:2

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Biomarkers; Cohort Studies; Female; Humans; Interleukin-6; Male; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity; Substance P; tau Proteins

2001
Substance P immunoreactivity in Alzheimer disease: a study in cases presenting symmetric or asymmetric cortical atrophy.
    Alzheimer disease and associated disorders, 1990, Volume: 4, Issue:1

    Topics: Aged; Alzheimer Disease; Atrophy; Cerebral Cortex; Humans; Immunohistochemistry; Middle Aged; Substance P

1990
Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing.
    Science (New York, N.Y.), 1990, Apr-27, Volume: 248, Issue:4954

    Topics: Aged; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Membrane; Cells, Cultured; Cloning, Molecular; DNA, Recombinant; Glycosylation; Half-Life; Humans; Immunoblotting; Molecular Weight; Plasmids; Protein Precursors; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Substance P; Transfection

1990
Immunohistochemical study of the striatal efferents and nigral dopaminergic neurons in parkinsonism-dementia complex on Guam in comparison with those in Parkinson's and Alzheimer's diseases.
    Annals of neurology, 1990, Volume: 27, Issue:5

    Topics: Alzheimer Disease; Calcineurin; Calmodulin-Binding Proteins; Corpus Striatum; Dementia; Dopamine; Enkephalin, Methionine; Guam; Humans; Immunohistochemistry; Neuropeptides; Parkinson Disease; Phosphoprotein Phosphatases; Substance P; Substantia Nigra; Tyrosine 3-Monooxygenase

1990
Substance P-like immunoreactivity, choline acetyltransferase activity and cholinergic muscarinic receptors in Alzheimer's disease and multi-infarct dementia.
    Brain research, 1990, Jun-25, Volume: 521, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Choline O-Acetyltransferase; Dementia, Multi-Infarct; Female; Humans; Male; Receptors, Muscarinic; Substance P

1990
Reduction of neurotensin immunoreactivity in the amygdala in Alzheimer's disease.
    Brain research, 1990, Dec-24, Volume: 537, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amygdala; Brain; Female; Humans; Male; Neurotensin; Somatostatin; Substance P

1990
Substance P-like immunoreactive neurons are depleted in Alzheimer's disease cerebral cortex.
    Neuroscience, 1991, Volume: 41, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antibodies, Monoclonal; Cerebral Cortex; Humans; Middle Aged; Nerve Degeneration; Neurons; Substance P

1991
Subtypes and differential laminar distributions of beta A4 deposits in Alzheimer's disease: relationship with the intellectual status of 26 cases.
    Acta neuropathologica, 1991, Volume: 81, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Female; Humans; Intelligence Tests; Staining and Labeling; Substance P

1991
New clue found to Alzheimer's.
    Science (New York, N.Y.), 1991, Aug-23, Volume: 253, Issue:5022

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Rats; Substance P

1991
Substance P immunoreactivity within neuritic plaques.
    Neuroscience letters, 1985, Jul-04, Volume: 58, Issue:1

    Topics: Aged; Alzheimer Disease; Brain; Histocytochemistry; Humans; Immunochemistry; Middle Aged; Nerve Degeneration; Substance P

1985
Somatostatin-like immunoreactivity and substance-P-like immunoreactivity in the CSF of patients with senile dementia of Alzheimer type, multi-infarct syndrome and communicating hydrocephalus.
    Journal of neurology, 1985, Volume: 232, Issue:6

    Topics: Aged; Alzheimer Disease; Cerebral Infarction; Female; Humans; Hydrocephalus; Male; Middle Aged; Radioimmunoassay; Somatostatin; Substance P; Syndrome

1985
Substance P neuronal cell bodies in the human brain: complete mapping by immunohistofluorescence.
    Neuroscience letters, 1986, Aug-15, Volume: 69, Issue:1

    Topics: Aged; Alzheimer Disease; Brain; Brain Diseases; Brain Ischemia; Fluorescent Antibody Technique; Humans; Spinal Cord; Substance P

1986
Choline acetyltransferase immunoreactivity in neuritic plaques of Alzheimer brain.
    Neuroscience letters, 1986, Nov-11, Volume: 71, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amygdala; Brain; Cerebral Cortex; Choline O-Acetyltransferase; Hippocampus; Humans; Neuropeptide Y; Somatostatin; Substance P

1986
Substance P-like immunoreactivity is reduced in Alzheimer's disease cerebral cortex.
    Neurology, 1987, Volume: 37, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Chromatography, High Pressure Liquid; Female; Hippocampus; Humans; Male; Middle Aged; Radioimmunoassay; Substance P

1987
Comparison of DSIP- (delta sleep-inducing peptide) and P-DSIP-like (phosphorylated) immunoreactivity in cerebrospinal fluid of patients with senile dementia of Alzheimer type, multi-infarct syndrome, communicating hydrocephalus and Parkinson's disease.
    Journal of neurology, 1987, Volume: 235, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Delta Sleep-Inducing Peptide; Dementia; Female; Humans; Hydrocephalus; Male; Middle Aged; Parkinson Disease; Peptides; Phosphoproteins; Radioimmunoassay; Substance P

1987
[The study of neuroactive substance within senile plaques--with special reference to somatostatin and substance P].
    Rinsho shinkeigaku = Clinical neurology, 1988, Volume: 28, Issue:1

    Topics: Alzheimer Disease; Hippocampus; Humans; Immunohistochemistry; Somatostatin; Substance P

1988
Substance P-like immunoreactivity in brains with pathological features of Parkinson's and Alzheimer's diseases.
    Brain research, 1989, May-08, Volume: 486, Issue:2

    Topics: Aged; Alzheimer Disease; Brain; Female; Humans; Immunohistochemistry; Male; Parkinson Disease; Substance P

1989
Substance P and somatostatin coexist within neuritic plaques: implications for the pathogenesis of Alzheimer's disease.
    Neuroscience, 1989, Volume: 31, Issue:3

    Topics: Aged; Alzheimer Disease; Amyloid; Female; Humans; Immunohistochemistry; Inclusion Bodies; Male; Somatostatin; Substance P

1989
Immunocytochemical studies of substance P and Met-enkephalin in the basal ganglia and substantia nigra in Huntington's, Parkinson's and Alzheimer's diseases.
    Journal of neuropathology and experimental neurology, 1985, Volume: 44, Issue:1

    Topics: Aged; Alzheimer Disease; Basal Ganglia; Enkephalin, Methionine; Humans; Huntington Disease; Immunochemistry; Middle Aged; Parkinson Disease; Radioimmunoassay; Substance P

1985