substance p has been researched along with Aging in 216 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (25.00) | 18.7374 |
| 1990's | 94 (43.52) | 18.2507 |
| 2000's | 47 (21.76) | 29.6817 |
| 2010's | 18 (8.33) | 24.3611 |
| 2020's | 3 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, N; Han, G; Hou, X; Li, Y; Liu, W; Wu, H; Xing, B; Zhang, J | 1 |
| Bazan, HEP; He, J; Pham, TL | 1 |
| Guo, TZ; Hou, S; Kingery, WS; Sabsovich, I; Wang, L; Wei, T | 1 |
| Aguirre, M; Cruz-Almeida, Y; Dasilva Ribeiro, MC; Eckert, NR; Edwards, RR; Riley, JL; Simon, CB; Sorenson, HL; Tighe, PJ; Wallet, SM | 1 |
| Cueno, ME; Imai, K | 1 |
| Alessandro, R; Fabio, B; Giulio, F; Marco, B; Paolo, R; Philippe, F | 1 |
| Gonkowski, S; Makowska, K | 1 |
| Allen, KA; Bello, NM; Bergamasco, L; Coetzee, JF; Dockweiler, JC; Edwards-Callaway, LN; Glynn, HD; Jones, ML; Miller, KA; Theurer, ME | 1 |
| Garcia-Galiano, D; Leon, S; Manfredi-Lozano, M; Navarro, VM; Pinilla, L; Roa, J; Ruiz-Pino, F; Sánchez-Garrido, MA; Tena-Sempere, M | 1 |
| Collier, TJ; Gebremedhin, KG; O'Malley, J; Paumier, KL; Rademacher, DJ; Sisson, KA; Sortwell, CE; Stancati, JA; Steece-Collier, K | 1 |
| Alpini, G; Bernuzzi, F; Francis, H; Glaser, S; Glaser, T; Huang, Q; Invernizzi, P; Kennedy, L; Meng, F; Venter, J; Wan, Y; Wu, N; Zhou, T | 1 |
| Piérard, GE; Quatresooz, P | 1 |
| Matsumoto, M; Miyagawa, I; Toji, S; Watanabe, T | 1 |
| Rance, NE | 1 |
| Collinson, JM; Kucerova, R; Lavery, DN; Leiper, LJ; Ou, J; Walczysko, P; West, JD | 1 |
| Burcher, E; King, DW; Liu, L; Lubowski, DZ; Morgan, MJ; Shang, F | 1 |
| Duenes, JA; Fatima, J; Iqbal, CW; Kasparek, MS; Sarr, MG | 2 |
| Chow, CW; Cook, DJ; Farmer, PJ; Hutson, JM; Keck, J; King, SK; Koh, TL; Lee, M; Ong, SY; Peck, CJ; Southwell, BR; Stanton, MP; Sutcliffe, JR; Wong, SQ | 1 |
| DeBerry, J; Ness, TJ; Randich, A; Robbins, MT; Shaffer, AD | 1 |
| Emanuilov, AI; Korzina, MB; Maslyukov, PM; Shilkin, VV | 1 |
| Dey, RD; Hunter, DD; Wu, Z | 1 |
| Costa, MS; dos Santos, JR; Duarte, RB; Freire, MA; Nunes, AC; Sousa, TB | 1 |
| Imamura, T; Ishikawa, M; Ishizuka, O; Kurizaki, Y; Nishizawa, O; Noguchi, W; Zhang, L | 1 |
| Cho, HJ; Joo, NS; Wine, JJ | 1 |
| May, CA | 1 |
| Géranton, SM; Hunt, SP; Man, SH | 1 |
| Chatterjee, V; Gashev, AA | 1 |
| Liu, H; Mazarati, A; Sankar, R; Shin, D; Wasterlain, C | 1 |
| Fahrenkrug, J; Hannibal, J; Mohammed, H; Santer, R | 1 |
| Adeghate, E; Draper, CE; Singh, J | 1 |
| Polston, EK; Simerly, RB | 1 |
| Aschenbach, JR; Gäbel, G; Pfannkuche, H; Schellhorn, C; Schemann, M | 1 |
| Frausto, A; Gruber, HE; Mills, BG; Norton, HJ; Rude, RK; Wei, LY | 1 |
| Chen, Q; Reiner, A; Sun, Z | 1 |
| Lee, LY; Ruan, T; Wu, ZX; Yang, QH | 1 |
| Mohammed, HA; Santer, RM | 1 |
| Cheng, JP; Ma, Y; Zhou, WX | 1 |
| Colasurdo, GN; Dakhama, A; Fratelli, C; Larsen, GL; Loader, J; Nguyen, DD | 1 |
| Priestley, DJ; Ranson, RN; Santer, RM; Watson, AH | 1 |
| Aita, M; Fujiwara, N; Maeda, T; Seo, K; Takagi, R | 1 |
| Hogeman, CS; Leuenberger, UA; Newcomer, SC; Proctor, DN | 1 |
| Riley, G | 1 |
| Jun-Ping, C; Wen-Xia, Z; Yong-Xiang, Z; Yuan, M | 1 |
| Hanzawa, N; Harada, T; Hitomi, S; Iwata, K; Kanda, K; Kitagawa, J; Masuda, Y; Ogawa, A; Ren, K; Saitoh, K; Takahashi, O; Tsuboi, Y | 1 |
| Bagnoli, P; Bosco, L; Casini, G; Catalani, E; Dal Monte, M; Fineschi, S; Gangitano, C; Lucattelli, M | 1 |
| Burns, D; Eskola, O; Hargreaves, R; Hietala, J; Kajander, J; Nyman, MJ; Sanabria, S; Solin, O; Vahlberg, T | 1 |
| Lagercrantz, H; Shvarev, YN | 1 |
| Dakhama, A; Fratelli, C; Kang, JK; Larsen, GL; Loader, J | 1 |
| Aicher, SA; Terman, GW; Thomson, LM; Zeng, J | 1 |
| Jalkanen, AJ; Jarho, EM; Mannila, A; Männistö, PT; Puttonen, KA; Ruotsalainen, S; Sinervä, V; Venäläinen, JI; Wallén, EA | 1 |
| Dulger, H; Erbilen, E; Guler, N; Gumrukcuoglu, HA; Kutay, V; Ozkara, C; Sahin, M | 1 |
| McDougall, JJ; Schuelert, N | 1 |
| Dhanasekaran, S; Mensah-Brown, E; Morrison, JF; Shaffiullah, M; Sheen, R; Shehab, S | 1 |
| Cheng, L; Goulding, M; Lima, D; Liu, Y; Lopes, C; Ma, Q; Qian, Y; Turner, EE; Xu, Y | 1 |
| Gamse, R; Lembeck, F; Mayer, N | 1 |
| Elde, RP; Graybiel, AM; Ragsdale, CW; Yoneoka, ES | 1 |
| Emson, PC; Holzbauer, M; Holzer, P; Iversen, LL; Sharman, DF | 1 |
| Boissier, JR; Dupont, A; Labrie, F; Mérand, Y; Savard, P | 1 |
| Brecha, N; Karten, HJ; Sharma, SC | 1 |
| Arregui, A; Blessed, G; Cross, AJ; Crow, TJ; Dimaline, R; Dockray, GJ; Perry, EK; Perry, RH; Tomlinson, BE | 1 |
| Buck, SH; Burks, TF; Deshmukh, PP; Yamamura, HI | 1 |
| Bloom, SR; Ghatei, MA; McGregor, GP; O'Shaughnessy, DJ; Polak, JM; Woodhams, PL | 1 |
| Hara, Y; Iida, H; Inagaki, S; Kawai, Y; Matsuzaki, T; Sakanaka, M; Senba, E; Shiosaka, S; Takagi, H; Takatsuki, K; Tohyama, M | 1 |
| Buck, SH; Burks, TF; Yamamura, HI | 1 |
| Atkinson, ME; Mohamed, SS | 1 |
| Hara, Y; Iida, H; Inagaki, S; Kawai, Y; Sakanaka, M; Senba, E; Shiosaka, S; Takagi, H; Takatsuki, K; Tohyama, M | 1 |
| Hara, Y; Inagaki, S; Kawai, Y; Sakanaka, M; Senba, E; Shiosaka, S; Takatsuki, K; Tohyama, M | 1 |
| Atzori, MG; Del Fiacco, M; Dessi, ML; Levanti, MC | 1 |
| Oehme, P; Roske, I | 1 |
| Hecht, K; Hilse, H; Oehme, P; Rathsack, R; Roske, I | 1 |
| Adler, JE; Black, IB | 1 |
| Bartke, A; Debeljuk, L; Rao, JN | 1 |
| Kitamura, N; Yamada, J; Yamamoto, Y; Yamashita, T | 1 |
| Abelli, L; Geppetti, P; Maggi, CA | 1 |
| Bennett, GW; Dagerlind, A; Fone, KC; Hökfelt, T; Johnson, H; Ulfhake, B | 1 |
| Dagerlind, A; Hertzberg, T; Hökfelt, T; Holgert, H; Lagercrantz, H | 1 |
| Harlan, RE; Zhang, L | 1 |
| Cummings, JF; Nixon, AJ | 1 |
| Frydryszak, H; Polanski, E; Stoessl, AJ | 1 |
| Ekman, R; Ekström, J; Håkanson, R | 1 |
| Bürger, K; Reuss, S | 1 |
| Mulderry, PK | 2 |
| Kiyoshima, T; Kondo, T; Nagata, E; Nakata, M; Tanaka, T | 1 |
| Beal, MF; Brouillet, E; Henshaw, DR; Hyman, BT; Jenkins, BG; Rosen, BR; Schulz, JB; Sodhi, P | 1 |
| Frisch, C; Hasenöhrl, RU; Huston, JP; Nikolaus, S | 1 |
| Colasurdo, GN; Graves, JP; Larsen, GL; Loader, JE | 1 |
| Del Fiacco, M; Lai, ML; Priestley, JV; Quartu, M; Setzu, MD | 1 |
| Adair, J; Filloux, F; Gibb, JW; Hanson, GR; Johnson, M | 1 |
| Benzer, A; Fischer-Colbrie, R; Gasser, RW; Hogue-Angeletti, R; Kirchmair, R; Marksteiner, J; Miller, C; Saria, A; Troger, J; Winkler, H | 1 |
| Salo, A; Uusitalo, H; Virta, E | 1 |
| Lai, YL; Tai, HH; Zhang, HQ | 1 |
| Iwamoto, Y; Kato, T; Okamiya, K; Toide, K | 1 |
| Ang, LC; Shul, DD | 1 |
| Barnes, PJ; Kuroume, T; Mochizuki, H; Morikawa, A; Tokuyama, K; Yokoyama, T | 1 |
| Corcoran, BM; Haigh, AL | 1 |
| Factor, EM; Hart, RP; Jonakait, GM | 1 |
| Constantine-Paton, M; Debski, EA | 1 |
| Apfel, SC; Arezzo, JC; Kessler, JA; Moran, M | 1 |
| Beal, MF; Brouillet, E; Henshaw, R; Hyman, BT; Jenkins, B; Rosen, B | 1 |
| Keller, RW; Snyder-Keller, AM | 1 |
| Dahlström, AB; Li, JY | 1 |
| Ogomori, K; Reusche, E; Rosenwald, A; Teichert, HM | 1 |
| Ahmed, M; Bjurholm, A; Kreicbergs, A; Sisask, G | 1 |
| Jiang, ZG; Smith, RA | 1 |
| Lau, SM; Tang, F | 1 |
| Hildebrand, C; Karlsson, M | 1 |
| Helme, R; Khalil, Z | 1 |
| Ciampoli, D; Newgreen, DF; Southwell, BR; Young, HM | 1 |
| Doutova, EA; Moss, NG | 1 |
| Ai, X; Hall, AK; Hickman, GE; MacPhedran, SE; Nduaguba, CO; Robertson, CP | 1 |
| Goodyer, C; Laferrière, A; Moss, IR; Paquette, J; Waters, KA | 1 |
| Hondo, E; Kitamura, N; Mimoda, T; Yamada, J | 1 |
| Geraghty, DP; Maguire, CM | 1 |
| Brandl, B; Wrobel, KH | 1 |
| Briaud, S; Eglen, RM; Ford, AP; Hegde, SS; Mandel, DA; Wilford, MR | 1 |
| Cowen, T; Johnson, RJ; Santer, RM; Schemann, M | 1 |
| Barneveld, A; Buma, P; Cornelissen, BP; Rijkenhuizen, AB | 1 |
| Dreshaj, IA; Haxhiu, MA; Martin, RJ; Mhanna, MJ | 1 |
| Bose, P; Vacca-Galloway, LL | 1 |
| Barrett, M; Bunker, CB; Mallon, E; Rosenberger, P; Rowe, A; Walsh, J | 1 |
| Goettl, VM; Hadjiconstantinou, M; Neff, NH; Tejwani, GA | 1 |
| Geraghty, DP; Mazzone, SB | 1 |
| Di Pasquale, E; Monteau, R; Ptak, K | 1 |
| Kaneko, H; Shigenobu, K; Tanaka, H; Tanaka, Y | 1 |
| Mantyh, PW; Oyamada, H; Senba, E; Takatsuji, K; Tohyama, M | 1 |
| Rodman, HR; Sorenson, KM | 1 |
| Edvinsson, L; Saetrum Opgaard, O; Saxena, PR; Ytterberg, HT | 1 |
| Baltazar, ET; Hondo, E; Kitamura, N; Myojin, T; Pearson, GT; Yamada, J | 1 |
| Hondo, E; Kitamura, N; Nishi, Y; Otani, M; Taguchi, K; Yamada, J | 1 |
| Khalil, Z; Khodr, B | 1 |
| Bu, S; Sun, M; Zhang, Y | 1 |
| Khalil, Z; Livett, BG; Merhi, M | 1 |
| Elde, R; Fairbanks, CA; Guo, A; Simone, DA; Stone, LS; Wang, J | 1 |
| Bachis, A; Del Fiacco, M; Quartu, M; Serra, MP | 1 |
| Antalffy, B; Armstrong, D; Chakraborty, S; Deguchi, K; Glaze, D; Reyes, C | 1 |
| Bray, RC; Erwin, WM; Salo, PT; Seeratten, RA | 1 |
| Corbett, SA; Hukkanen, M; Konttinen, YT; Platts, LA; Polak, JM; Santavirta, S | 1 |
| Boyer, PA; De Nanteuil, G; Guez, D; Jochemsen, R; Lestage, P; Morain, P; Robin, JL | 1 |
| Debeljuk, L; Díaz, B; Díaz, E; Fernández, C | 1 |
| Clevenger, CM; DeSouza, CA; Greiner, JJ; Hoetzer, GL; Shapiro, LF; Smith, DT; Stauffer, BL | 1 |
| Emson, PC; Gilbert, RF | 1 |
| Hecht, K; Hecht, T; Oehme, P; Poppei, M | 1 |
| Kudo, N; Okado, N; Ozaki, S | 1 |
| Kawano, H; Masuko, S; Niwa, H; Takeichi, M | 1 |
| Fitzgerald, M; Reynolds, ML | 1 |
| Byers, MR; Swift, ML | 1 |
| Gibbs, LM; Kendig, JJ | 1 |
| Dees, WL; Ojeda, SR; Schultea, TD | 1 |
| Tang, F; Vacca-Galloway, LL; Yung, KK | 1 |
| Bell, C; Hendry, IA; Messina, A | 1 |
| Bishop, AE; Hitchcock, RJ; Pemble, MJ; Polak, JM; Spitz, L | 1 |
| Hyman, PE; Kimura, S; McRoberts, JA; Snape, WJ; Tomomasa, T; Yuan, QX | 1 |
| Marlier, L; Poulat, P; Privat, A; Rajaofetra, N; Sandillon, F | 1 |
| Alesci, R; Bagnoli, P; Erichsen, JT; Fontanesi, G | 1 |
| Andersson, PO; Fahrenkrug, J; Malmgren, A; Uvelius, B | 1 |
| Benoit, SE; Hoogasian, J; Jonassen, JA; Leeman, SE; Mullikin-Kilpatrick, D | 1 |
| Sharma, SC; Vecino, E | 1 |
| Arakawa, H; Barnes, PJ; Kuroume, T; Mochizuki, H; Morikawa, A; Tokuyama, K; Yokoyama, T | 1 |
| Curry, M; Martinez, JR; Ramsey, RC; Seagrave, JC | 1 |
| Del Fiacco, M; Diaz, G; Floris, A; Quartu, M | 2 |
| Hasenöhrl, RU; Huston, JP; Schuurman, T | 1 |
| Chae, HY; Parvin, CA; Roth, KA; Schmidt, RE | 1 |
| Eggerman, KW; Payne, E; Sprung, RF; Wesche, DE; Zahm, DS | 1 |
| Cheung, A; Tang, F; Vacca-Galloway, LL | 1 |
| Bijlani, V; Jotwani, G; Rath, S; Wadhwa, S | 1 |
| Snyder-Keller, AM | 1 |
| Beiras, A; Gallego, R; García-Caballero, T; Rosón, E | 1 |
| Bouvier, R; Chayvialle, JA; Chigr, F; Kopp, N; Leduque, P; Najimi, M | 1 |
| Coderre, TJ; Gonzales, R; Levine, JD; Sherbourne, CD | 1 |
| Armstrong, EP; Buchanan, KD; Eedy, DJ; Johnston, CF; Shaw, C | 1 |
| Katsumata, U; Nakazawa, H; Sasaki, H; Sekizawa, K; Takasugi, R; Ujie, Y | 1 |
| Chong, PN; de Ceballos, ML; Jenner, P; Marsden, CD; Rose, S; Taylor, MD | 1 |
| Burnstock, G; Corr, LA; Poole-Wilson, P | 1 |
| Jonassen, JA; Leeman, SE | 1 |
| Lagercrantz, H; Prabhakar, N; Srinivasan, M; Yamamoto, Y | 1 |
| Hoefnagels, WH; Jansen, RW | 1 |
| Koike, K; Kurata, R; Moriya, M; Takayanagi, I | 1 |
| Del Rio, JA; Ferrer, I; Soriano, E | 1 |
| MacLean, DB | 1 |
| Duckles, SP | 1 |
| Burnstock, G; Cowen, T; Dhall, U; Haven, AJ | 1 |
| Nguyen-Legros, J; Versaux-Botteri, C; Vigny, A | 1 |
| Charlton, CG; Helke, CJ | 1 |
| Castren, E; Kurihara, M; Niwa, M; Saavedra, JM; Shigematsu, K | 1 |
| Harrison, FA; Wathuta, EM | 1 |
| Helme, RD; McKernan, S | 1 |
| Abelli, L; Giuliani, S; Maggi, CA; Meli, A; Regoli, D; Santicioli, P | 1 |
| Del Fiacco, M; Dessi, ML; Levanti, MC; Zucca, G | 1 |
| Amenta, F; Frilli, S; Geppetti, P; Maggi, CA; Meli, A; Santicioli, P; Spillantini, MG; Zecchi-Orlandini, S | 1 |
| Buske, R; Hecht, K; Hilse, H; Oehme, P; Roske, I | 1 |
| Fehér, E; Pénzes, L | 1 |
| Del Fiacco, M; Levanti, MC; Perra, MT; Quartu, M; Rosa, MD; Zucca, G | 1 |
| Hendry, IA; Hill, CE; Jelinek, H; McLennan, IS; Rush, RA | 1 |
| Dam, TV; Escher, E; Quirion, R | 1 |
| Read, DJ; Scheibner, T; Sullivan, CE | 1 |
| Beaujouan, JC; Glowinski, J; Murray, M; Saffroy, M; Torrens, Y | 1 |
| Handelmann, GE; O'Donohue, TL; Shults, CW | 1 |
| Amenta, F; Cavallotti, C; Geppetti, P; Spillantini, MG | 1 |
| Frilli, S; Geppetti, P; Hunt, SP; Maggi, CA; Meli, A; Nediani, C; Santicioli, P; Spillantini, MG | 1 |
| Jonakait, GM; Ni, L | 2 |
| Burkhart, AB; Hamill, RW; Newton, BW; Romagnano, MA | 1 |
| Hammond, DL; Ruda, MA | 1 |
| Ito, S; Kimura, A; Ohga, A; Ohta, T | 1 |
| Brunner, SL; Gingras, JL; McNamara, MC | 1 |
| Renda, T; Salvi, E | 1 |
| Chiaia, NL; Hess, PR; Miller, MW; Rhoades, RW | 1 |
| Bodary, SC; Clegg, DO; Large, TH; Reichardt, LF | 1 |
| Himes, BT; Tessler, A | 1 |
| Okamura, T; Toda, N | 1 |
| Chang, KS; Li, XS; Tanz, RD | 1 |
| Bell, C; Gurusinghe, CJ | 1 |
| Govoni, S; Izumi, F; Kobayashi, H; Magnoni, MS; Trabucchi, M; Wada, A | 1 |
5 review(s) available for substance p and Aging
| Article | Year |
|---|---|
Chronic tendon pathology: molecular basis and therapeutic implications.
Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Collagen; Cumulative Trauma Disorders; Extracellular Matrix; Glycoproteins; Humans; Matrix Metalloproteinases; Middle Aged; Neuropeptides; Proteoglycans; Rupture; Substance P; Tendinopathy; Tendon Injuries; Tendons | 2005 |
S 17092: a prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies.
Topics: Aging; Animals; Cognition Disorders; Humans; Indoles; Learning; Memory Disorders; Models, Animal; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P; Thiazoles; Thiazolidines | 2002 |
Functional role of substance P for respiratory control during development.
Topics: Aging; Animals; Brain; Humans; Infant, Newborn; Neurotransmitter Agents; Protein Precursors; Respiration; Substance P; Sudden Infant Death; Tachykinins | 1991 |
Hormonal mechanisms of postprandial hypotension.
Topics: Aging; Food; Humans; Hypotension; Insulin; Neurotensin; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1991 |
Neuronal control of brain microvessel function.
Topics: Acetylcholine; Aging; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Capillaries; Capillary Permeability; Cerebrovascular Circulation; Cholecystokinin; Diabetes Mellitus; Dopamine; Endothelium; Histamine; Hypertension; Hypoxia, Brain; Locus Coeruleus; Microcirculation; Neural Pathways; Neurons; Norepinephrine; Receptors, Neurotransmitter; Serotonin; Substance P; Vasoactive Intestinal Peptide | 1985 |
4 trial(s) available for substance p and Aging
| Article | Year |
|---|---|
Effect of castration method on neurohormonal and electroencephalographic stress indicators in Holstein calves of different ages.
Topics: Aging; Analgesics; Animal Welfare; Animals; Cattle; Cattle Diseases; Electroencephalography; Heart Rate; Hydrocortisone; Male; Orchiectomy; Pain; Pain Measurement; Stress, Physiological; Substance P | 2013 |
Immunohistochemical clues at aging of the skin microvascular unit.
Topics: Adult; Aged; Aging; Antigens, CD34; Capsaicin; Dendritic Cells; Factor XIIIa; Humans; Immunohistochemistry; Male; Microvessels; Sensory System Agents; Skin; Substance P; Thrombomodulin | 2009 |
Molecular characterization of immunoreactivities of peptides derived from chromogranin A (GE-25) and from secretogranin II (secretoneurin) in human and bovine cerebrospinal fluid.
Topics: Adult; Aged; Aging; Animals; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromogranin A; Chromogranins; Humans; Middle Aged; Neuropeptides; Radioimmunoassay; Secretogranin II; Sex Characteristics; Substance P | 1994 |
Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adult; Aged; Aging; Blood Pressure; Body Composition; Bradykinin; Endothelium, Vascular; Forearm; Humans; Infusions, Intra-Arterial; Isoproterenol; Male; Middle Aged; Nitroprusside; Regional Blood Flow; Substance P; Vasodilation; Vasodilator Agents; Vital Capacity | 2002 |
207 other study(ies) available for substance p and Aging
| Article | Year |
|---|---|
Pinocembrin relieves hip fracture-induced pain by repressing spinal substance P signaling in aged rats.
Topics: Aging; Animals; Disease Models, Animal; Flavanones; Hip Fractures; Indoles; Male; Neurokinin-1 Receptor Antagonists; Nociceptive Pain; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P | 2022 |
Neuroanatomy of Adult and Aging Chicken Cornea.
Topics: Adult; Aging; Animals; Calcitonin Gene-Related Peptide; Chickens; Cornea; Female; Humans; Male; Mammals; Neuroanatomy; Neuropeptides; Substance P | 2022 |
Mice lacking substance P have normal bone modeling but diminished bone formation, increased resorption, and accelerated osteopenia with aging.
Topics: Aging; Animals; Bone and Bones; Bone Diseases, Metabolic; Bone Resorption; Mice; Osteogenesis; Substance P | 2021 |
Age Differences in the Time Course and Magnitude of Changes in Circulating Neuropeptides After Pain Evocation in Humans.
Topics: Aged; Aging; Analysis of Variance; beta-Endorphin; Biomarkers; Cold Temperature; Female; Hot Temperature; Humans; Male; Pain; Pressure; Substance P; Time Factors; Young Adult | 2017 |
Various cellular stress components change as the rat ages: An insight into the putative overall age-related cellular stress network.
Topics: Age Factors; Aging; Animals; Biomarkers; Endoplasmic Reticulum Stress; Hydrogen Peroxide; Male; NADP; Nitrosative Stress; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Substance P; Transcription Factor CHOP | 2018 |
The Effect of Aging on Nerve Morphology and Substance P Expression in Mouse and Human Corneas.
Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Cornea; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Middle Aged; Substance P; Trigeminal Nerve; Young Adult | 2018 |
Age and Sex-Dependent Differences in the Neurochemical Characterization of Calcitonin Gene-Related Peptide-Like Immunoreactive (CGRP-LI) Nervous Structures in the Porcine Descending Colon.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Colon, Descending; Female; Galanin; Male; Nerve Tissue Proteins; Neurons; Nitric Oxide Synthase Type I; Sex Characteristics; Substance P; Swine; Vesicular Acetylcholine Transport Proteins | 2019 |
Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats.
Topics: Aging; Animals; Dynorphins; Enkephalins; Female; Follicle Stimulating Hormone; Hypothalamus; Kisspeptins; Luteinizing Hormone; Male; Neurokinin B; Peptide Fragments; Protein Precursors; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 2015 |
Interrogating the aged striatum: robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration.
Topics: Aging; Amphetamine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Embryo, Mammalian; Functional Laterality; Levodopa; Neurites; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Recovery of Function; Stem Cell Transplantation; Substance P | 2015 |
Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells.
Topics: Aging; Animals; Apoptosis; Bile Ducts; Biomarkers; Biopsy, Needle; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Hepatic Stellate Cells; Humans; Immunohistochemistry; Liver Cirrhosis; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Random Allocation; RNA, Messenger; Sensitivity and Specificity; Substance P | 2017 |
Effects of estrogen on age-related changes in muscarinic responsiveness of the urinary bladder and lumbosacral dorsal root ganglion cells in female rats.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Estrogens; Female; Ganglia, Spinal; Gene Expression Regulation; Immunohistochemistry; Lumbosacral Region; Muscarine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Purinergic P2; Receptors, Purinergic P2X3; RNA, Messenger; Substance P; Urinary Bladder; Urination | 2008 |
Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback.
Topics: Aging; Animals; Dynorphins; Estrogens; Feedback, Physiological; Female; Humans; Hypothalamus; Kisspeptins; Menopause; Middle Aged; Neurokinin B; Neurons; Neurosecretory Systems; Ovary; Rats; Substance P; Tumor Suppressor Proteins | 2009 |
Control of patterns of corneal innervation by Pax6.
Topics: Aging; Animals; Cell Movement; Cornea; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Eye Proteins; Female; Fluorescent Antibody Technique, Indirect; Homeodomain Proteins; Male; Mice; Mice, Inbred CBA; Mice, Knockout; Nerve Fibers; Nerve Regeneration; Paired Box Transcription Factors; PAX6 Transcription Factor; Repressor Proteins; Substance P; Trigeminal Ganglion; Tubulin; Wound Healing | 2009 |
Cyclooxygenase-dependent alterations in substance P-mediated contractility and tachykinin NK1 receptor expression in the colonic circular muscle of patients with slow transit constipation.
Topics: Acetylcholine; Adult; Aged; Aging; Atropine; Colon, Sigmoid; Constipation; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Enteric Nervous System; Female; Ganglionic Stimulants; Gastrointestinal Transit; Humans; In Vitro Techniques; Kinetics; Middle Aged; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Neurokinin A; Nicotinic Agonists; Prostaglandin-Endoperoxide Synthases; Receptors, Neurokinin-1; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Substance P; Tetrodotoxin; Young Adult | 2009 |
Age-related changes in functional NANC innervation with VIP and substance P in the jejunum of Lewis rats.
Topics: Aging; Animals; Electric Stimulation; Enteric Nervous System; Excitatory Postsynaptic Potentials; Gastrointestinal Motility; Inhibitory Postsynaptic Potentials; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Neuronal Plasticity; Rats; Rats, Inbred Lew; Substance P; Synaptic Transmission; Vasoactive Intestinal Peptide | 2009 |
Decrease in nerve fibre density in human sigmoid colon circular muscle occurs with growth but not aging.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Cell Count; Child; Child, Preschool; Colon, Sigmoid; Female; Humans; Immunohistochemistry; Male; Microscopy, Confocal; Middle Aged; Muscle Development; Muscle, Smooth; Nerve Fibers; Nitric Oxide Synthase Type I; Substance P; Vasoactive Intestinal Peptide | 2010 |
Neonatal bladder inflammation produces functional changes and alters neuropeptide content in bladders of adult female rats.
Topics: Aging; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Cystitis; Disease Models, Animal; Evans Blue; Female; Irritants; Mustard Plant; Neuropeptides; Nociceptors; Plant Oils; Rats; Sensory Receptor Cells; Substance P; Time; Urinary Bladder; Zymosan | 2010 |
Neurotransmitter composition of neurons in the cranial cervical and celiac sympathetic ganglia in postnatal ontogenesis.
Topics: Aging; Animals; Animals, Newborn; Cell Size; Choline O-Acetyltransferase; Ganglia, Sympathetic; Immunohistochemistry; Neurons; Neuropeptide Y; Neurotransmitter Agents; Rats; Substance P; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 2010 |
Sensory neural responses to ozone exposure during early postnatal development in rat airways.
Topics: Aging; Animals; Animals, Newborn; Humans; Lung; Muscle, Smooth; Nerve Fibers; Ozone; Rats; Respiratory Function Tests; Sensory Receptor Cells; Substance P; Time Factors | 2010 |
Expression of the immediate-early gene egr-1 and substance P in the spinal cord following locomotor training in adult rats.
Topics: Aging; Animals; Early Growth Response Protein 1; Immunohistochemistry; Lumbar Vertebrae; Neuronal Plasticity; Neurons; Physical Conditioning, Animal; Posterior Horn Cells; Rats; Rats, Wistar; Sacrum; Spinal Cord; Substance P | 2010 |
A galenical of traditional Chinese herbal mixture (THC-002) reduces expression of tachykinin peptides within urethras of spontaneously hypertensive rats.
Topics: Aging; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Models, Animal; Neurokinin A; Neurokinin B; Rats; Rats, Inbred SHR; RNA, Messenger; Sodium Chloride; Substance P; Urethra | 2012 |
Defective fluid secretion from submucosal glands of nasal turbinates from CFTR-/- and CFTR (ΔF508/ΔF508) pigs.
Topics: Aging; Animals; Animals, Newborn; Body Fluids; Carbachol; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Synergism; Exocrine Glands; Mutation; Organ Size; Substance P; Sus scrofa; Trachea; Turbinates | 2011 |
Changes of the vasculature and innervation in the anterior segment of the RCS rat eye.
Topics: Adrenergic Fibers; Age Factors; Aging; Animals; Anterior Eye Segment; Arterioles; Calcitonin Gene-Related Peptide; Capillaries; Dilatation, Pathologic; Disease Models, Animal; Iris; Microvessels; Nerve Fibers; Rats; Retinal Dystrophies; Substance P; Tyrosine 3-Monooxygenase; Venules | 2011 |
Lamina I NK1 expressing projection neurones are functional in early postnatal rats and contribute to the setting up of adult mechanical sensory thresholds.
Topics: Aging; Animals; Animals, Newborn; Male; Mechanotransduction, Cellular; Neurons; Physical Stimulation; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Sensory Thresholds; Substance P; Weight Gain | 2012 |
Aging-associated shifts in functional status of mast cells located by adult and aged mesenteric lymphatic vessels.
Topics: Age Factors; Aging; Animals; Anoctamin-1; Biomarkers; Cellular Microenvironment; Chloride Channels; Histidine Decarboxylase; Immunoglobulin E; Immunohistochemistry; Intramolecular Oxidoreductases; Lipocalins; Lymphatic Vessels; Male; Mast Cells; Mesentery; p-Methoxy-N-methylphenethylamine; Peptidoglycan; Proto-Oncogene Proteins c-kit; Rats; Rats, Inbred F344; Staining and Labeling; Staphylococcus aureus; Substance P; Tryptases; Tumor Necrosis Factor-alpha | 2012 |
Epileptogenesis during development: injury, circuit recruitment, and plasticity.
Topics: Aging; Animals; Animals, Newborn; Convulsants; Dentate Gyrus; Electric Stimulation; Hippocampus; Immunohistochemistry; Lithium; Mossy Fibers, Hippocampal; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Perforant Pathway; Phosphopyruvate Hydratase; Pilocarpine; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Recruitment, Neurophysiological; Status Epilepticus; Substance P | 2002 |
Distribution and regional variation of pituitary adenylate cyclase activating polypeptide and other neuropeptides in the rat urinary bladder and ureter: effects of age.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Male; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Substance P; Tissue Distribution; Ureter; Urinary Bladder; Vasoactive Intestinal Peptide | 2002 |
Effects of age on morphology, protein synthesis and secretagogue-evoked secretory responses in the rat lacrimal gland.
Topics: Age Factors; Aging; Animals; Cytoplasm; Endoplasmic Reticulum, Rough; Golgi Apparatus; Histamine; Immunohistochemistry; Lacrimal Apparatus; Leucine; Male; Microscopy, Electron; Microscopy, Fluorescence; Peroxidases; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Serotonin; Substance P; Time Factors; Vasoactive Intestinal Peptide | 2003 |
Sex-specific patterns of galanin, cholecystokinin, and substance P expression in neurons of the principal bed nucleus of the stria terminalis are differentially reflected within three efferent preoptic pathways in the juvenile rat.
Topics: Aging; Animals; Cholecystokinin; Efferent Pathways; Female; Galanin; Immunohistochemistry; Male; Neurons; Neuropeptides; Phytohemagglutinins; Preoptic Area; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Septal Nuclei; Sex Characteristics; Sexual Maturation; Substance P | 2003 |
Age-associated plasticity in the intrinsic innervation of the ovine rumen.
Topics: Aging; Animals; Animals, Suckling; Choline O-Acetyltransferase; Immunohistochemistry; Myenteric Plexus; Neuronal Plasticity; Nitric Oxide Synthase; Rumen; Sheep; Substance P; Vasoactive Intestinal Peptide | 2003 |
Bone loss induced by dietary magnesium reduction to 10% of the nutrient requirement in rats is associated with increased release of substance P and tumor necrosis factor-alpha.
Topics: Aging; Alkaline Phosphatase; Amino Acids; Animals; Body Weight; Bone and Bones; Bone Density; Bone Diseases; Bone Remodeling; Calcitriol; Calcium; Diet; Immunohistochemistry; Macrophages; Magnesium; Magnesium Deficiency; Megakaryocytes; Nutritional Requirements; Osteocalcin; Osteoclasts; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Substance P; Tumor Necrosis Factor-alpha | 2004 |
Enkephalinergic striatal projection neurons become less affected by quinolinic acid than substance P-containing striatal projection neurons as rats age.
Topics: Aging; Animals; Cell Survival; Corpus Striatum; Efferent Pathways; Enkephalins; In Situ Hybridization; Injections, Intraventricular; Male; Neurons; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance P | 2003 |
Influence of maturation on constrictive response to stimulation of C-fiber afferents in isolated guinea pig airways.
Topics: Aging; Animals; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Nerve Fibers, Unmyelinated; Neurokinin A; Neurons, Afferent; Osmolar Concentration; Radioimmunoassay; Stimulation, Chemical; Substance P; Trachea; Vasoconstriction | 2004 |
Distribution and changes with age of calcitonin gene-related peptide- and substance P-immunoreactive nerves of the rat urinary bladder and lumbosacral sensory neurons.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Immunohistochemistry; Lumbosacral Region; Male; Microscopy, Fluorescence; Neurons; Neurons, Afferent; Peptides; Rats; Rats, Wistar; Substance P; Time Factors; Urinary Bladder | 2002 |
[Study on effect and mechanism of liuwei dihuang decoction in modulating hypothalamus-pituitary-ovary axis in senescence accelerated mice model].
Topics: Aging; Animals; beta-Endorphin; Drugs, Chinese Herbal; Estradiol; Estrous Cycle; Female; Hypothalamo-Hypophyseal System; Mice; Ovary; Substance P | 2004 |
Mechanisms determining cholinergic neural responses in airways of young and mature rabbits.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Autonomic Nervous System; Bronchoconstrictor Agents; Choline O-Acetyltransferase; Electric Stimulation; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nerve Growth Factors; Rabbits; Receptor, Muscarinic M2; Receptors, Cholinergic; Respiratory Mechanics; Substance P; Trachea | 2004 |
Changes in the substance P-containing innervation of the lumbosacral spinal cord in male Wistar rats as a consequence of ageing.
Topics: Aging; Animals; Copulation; Down-Regulation; Immunohistochemistry; Lumbosacral Region; Male; Motor Neurons; Nerve Degeneration; Neural Pathways; Neurons; Parasympathetic Nervous System; Penile Erection; Presynaptic Terminals; Rats; Rats, Wistar; Reflex; Spinal Cord; Substance P; Urination | 2005 |
Postnatal changes in the spatial distributions of substance P and neurokinin-1 receptor in the trigeminal subnucleus caudalis of mice.
Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Immunohistochemistry; Mice; Mice, Inbred C57BL; Nociceptors; Pain; Presynaptic Terminals; Receptors, Neurokinin-1; Substance P; Synaptic Transmission; Trigeminal Caudal Nucleus | 2005 |
Heterogeneous vasodilator responses of human limbs: influence of age and habitual endurance training.
Topics: Acetylcholine; Adult; Aged; Aging; Arm; Dose-Response Relationship, Drug; Humans; Leg; Male; Middle Aged; Nitroprusside; Physical Education and Training; Physical Endurance; Regional Blood Flow; Substance P; Vasodilation; Vasodilator Agents | 2005 |
Age-related changes in the oestrous cycle and reproductive hormones in senescence-accelerated mouse.
Topics: Aging; Animals; beta-Endorphin; Diestrus; Estradiol; Estrous Cycle; Female; Hypothalamus; Luteinizing Hormone; Male; Mice; Mice, Inbred AKR; Pituitary Gland; Reproduction; Substance P | 2005 |
Involvement of dorsal column nucleus neurons in nociceptive transmission in aged rats.
Topics: Action Potentials; Age Factors; Aging; Animals; Brain Mapping; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Immunohistochemistry; Neurons; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Inbred F344; Reaction Time; Spinal Cord; Substance P; Thalamic Nuclei; Time Factors | 2005 |
Expression of substance P, neurokinin 1 receptors (NK1) and neurokinin 3 receptors in the developing mouse retina and in the retina of NK1 knockout mice.
Topics: Aging; Animals; Base Sequence; Cyclophilins; DNA Primers; Gene Expression Regulation, Developmental; Mice; Mice, Knockout; Peptidylprolyl Isomerase; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Retina; RNA, Messenger; Substance P | 2006 |
Gender and age affect NK1 receptors in the human brain - a positron emission tomography study with [18F]SPA-RQ.
Topics: Adult; Aging; Brain; Brain Chemistry; Brain Mapping; Dopamine; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Piperidines; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Neurokinin-1; Regression Analysis; Sex Characteristics; Substance P; Tetrazoles | 2007 |
Early postnatal changes in respiratory activity in rat in vitro and modulatory effects of substance P.
Topics: Aging; Animals; Animals, Newborn; Brain Stem; Data Interpretation, Statistical; In Vitro Techniques; Medulla Oblongata; Motor Neurons; Nerve Net; Neurons; Rats; Respiratory Mechanics; Spinal Cord; Substance P | 2006 |
Neuropeptide release from airways of young and fully-grown rabbits.
Topics: Aging; Animals; Follow-Up Studies; Immunohistochemistry; Muscle, Smooth; Nerve Growth Factor; Neurons; Neuropeptides; Photomicrography; Physical Stimulation; Rabbits; Substance P; Trachea; Vasoactive Intestinal Peptide | 2006 |
Primary afferent NMDA receptors increase dorsal horn excitation and mediate opiate tolerance in neonatal rats.
Topics: Afferent Pathways; Aging; Analgesics, Opioid; Animals; Animals, Newborn; Cell Differentiation; Drug Tolerance; Excitatory Postsynaptic Potentials; Ganglia, Spinal; Microscopy, Immunoelectron; Neurons, Afferent; Nociceptors; Pain; Patch-Clamp Techniques; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Nerve Roots; Substance P; Synaptic Transmission | 2006 |
Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats.
Topics: Aging; Amnesia; Animals; Frontal Lobe; Hippocampus; Hypothalamus; Inositol 1,4,5-Trisphosphate; Male; Maze Learning; Memory; Motor Activity; Muscarinic Antagonists; Neurotensin; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Wistar; Scopolamine; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P | 2007 |
Do cardiac neuropeptides play a role in the occurrence of atrial fibrillation after coronary bypass surgery?
Topics: Adrenergic beta-Antagonists; Aging; Angiotensin II; Atrial Fibrillation; Coronary Artery Bypass; Diabetes Complications; Echocardiography; Female; Humans; Male; Middle Aged; Mitral Valve; Myocardium; Neuropeptide Y; Postoperative Period; Prospective Studies; Sodium; Stroke Volume; Substance P | 2007 |
Age alters the ability of substance P to sensitize joint nociceptors in guinea pigs.
Topics: Adult; Aged; Aging; Animals; Electrophysiology; Female; Guinea Pigs; Humans; Knee Joint; Male; Mechanoreceptors; Middle Aged; Nociceptors; Substance P | 2007 |
Sensory and autonomic nerve changes in the monosodium glutamate-treated rat: a model of type II diabetes.
Topics: Aging; Animals; Autonomic Nervous System; Blood Glucose; Body Weight; Calcitonin Gene-Related Peptide; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Glucose Intolerance; Glucose Tolerance Test; Hot Temperature; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Neurons, Afferent; Obesity; Organ Size; Pain Measurement; Physical Stimulation; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Neurokinin-1; Sodium Glutamate; Substance P | 2008 |
Effect of chronic, extrinsic denervation on functional NANC innervation with vasoactive intestinal polypeptide and substance P in longitudinal muscle of rat jejunum.
Topics: Aging; Animals; Data Interpretation, Statistical; Denervation; Electric Stimulation; Enteric Nervous System; Immunohistochemistry; Intestine, Small; Jejunum; Male; Microscopy, Fluorescence; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Rats; Rats, Inbred Lew; Substance P; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 2008 |
Tlx1 and Tlx3 coordinate specification of dorsal horn pain-modulatory peptidergic neurons.
Topics: Aging; Animals; Animals, Newborn; Cholecystokinin; Embryo, Mammalian; Gene Expression Regulation; Homeodomain Proteins; Mice; Mice, Transgenic; Mutation; Neurokinin B; Neurons; Neuropeptides; Pain; PAX2 Transcription Factor; Somatostatin; Spinal Cord; Substance P; Transcription Factor Brn-3A; Transcription, Genetic | 2008 |
Effect of capsaicin pretreatment on substance P binding to synaptic vesicles.
Topics: Aging; Animals; Animals, Newborn; Binding Sites; Brain; Capsaicin; Fatty Acids, Unsaturated; Female; Male; Rats; Spinal Cord; Spinal Nerve Roots; Substance P; Synaptic Vesicles | 1980 |
An immunohistochemical study of enkephalins and other neuropeptides in the striatum of the cat with evidence that the opiate peptides are arranged to form mosaic patterns in register with the striosomal compartments visible by acetylcholinesterase stainin
Topics: Acetylcholinesterase; Aging; Animals; Animals, Newborn; Cats; Caudate Nucleus; Corpus Striatum; Endorphins; Enkephalins; Immunoenzyme Techniques; Microscopy, Fluorescence; Nucleus Accumbens; Putamen; Substance P | 1981 |
Tissue distribution of substance P in the domestic pig during postnatal development.
Topics: Aging; Animals; Brain; Duodenum; Female; Ileum; Male; Pituitary Gland; Skin; Spinal Cord; Substance P; Swine | 1981 |
Age-related changes in central nervous system enkephalins and substance P.
Topics: Aging; Animals; beta-Endorphin; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Hypothalamus; Male; Rats; Rats, Inbred Strains; Substance P | 1981 |
Localization of substance P-like immunoreactivity in the adult and developing goldfish retina.
Topics: Aging; Animals; Fluorescent Antibody Technique; Goldfish; Neurons; Retina; Substance P | 1981 |
Neurochemical activities in human temporal lobe related to aging and Alzheimer-type changes.
Topics: Aged; Aging; Alzheimer Disease; Cholecystokinin; Choline O-Acetyltransferase; Cognition; Dementia; Dopamine beta-Hydroxylase; Glutamate Decarboxylase; Humans; Middle Aged; Somatostatin; Substance P; Temporal Lobe; Vasoactive Intestinal Peptide | 1981 |
A survey of substance P, somatostatin, and neurotensin levels in aging in the rat and human central nervous system.
Topics: Adolescent; Adult; Aged; Aging; Animals; Brain; Brain Chemistry; Humans; Middle Aged; Neurotensin; Organ Specificity; Rats; Rats, Inbred F344; Somatostatin; Substance P | 1981 |
Developmental changes in bombesin, substance P, somatostatin and vasoactive intestinal polypeptide in the rat brain.
Topics: Aging; Animals; Bombesin; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Diencephalon; Female; Gastrointestinal Hormones; Hippocampus; Mesencephalon; Peptides; Pregnancy; Rats; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1982 |
Experimental and immunohistochemical studies on the cerebellar substance P of the rat: localization, postnatal ontogeny and ways of entry to the cerebellum.
Topics: Afferent Pathways; Aging; Animals; Cerebellar Nuclei; Cerebellum; Microscopy, Fluorescence; Nerve Fibers; Neurons; Rats; Substance P | 1982 |
Neuropeptide alterations in the central nervous system in aging.
Topics: Aging; Animals; Brain; Central Nervous System; Humans; Male; Neurotensin; Peptides; Rats; Rats, Inbred F344; Somatostatin; Species Specificity; Substance P | 1982 |
The ontogeny of substance P fibers in the mouse trigeminal nerve.
Topics: Aging; Animals; Female; Fluorescent Antibody Technique; Gestational Age; Mice; Mucous Membrane; Pharynx; Pregnancy; Substance P; Trigeminal Nerve | 1982 |
Ontogeny of substance P-containing neuron system of the rat: immunohistochemical analysis--II. Lower brain stem.
Topics: Aging; Animals; Brain Mapping; Brain Stem; Female; Fluorescent Antibody Technique; Gestational Age; Male; Neurons; Pregnancy; Rats; Substance P | 1982 |
Ontogeny of the peptidergic system in the rat spinal cord: immunohistochemical analysis.
Topics: Aging; Animals; Enkephalin, Leucine; Female; Fluorescent Antibody Technique; Ganglia, Spinal; Gestational Age; Male; Neural Pathways; Neurons; Neurotensin; Pregnancy; Rats; Somatostatin; Spinal Cord; Substance P; Synaptic Transmission | 1982 |
Substance P in the human brainstem. Preliminary results of its immunohistochemical localization.
Topics: Aged; Aging; Brain Stem; Fluorescent Antibody Technique; Humans; Infant, Newborn; Infant, Premature; Male; Substance P | 1983 |
Action of substance P on the blood pressure of spontaneously hypertensive rats in dependence on age.
Topics: Aging; Animals; Blood Pressure; Hypertension; Rats; Substance P | 1983 |
[Blood pressure and substance P-like immunoreactivity in the adrenal medulla and plasma of normotensive Wistar Kyoto rats and spontaneously hypertensive rats of varying age under acute stress].
Topics: Adrenal Medulla; Aging; Animals; Blood Pressure; Humans; Hypertension; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Stress, Psychological; Substance P | 1983 |
Plasticity of substance P in mature and aged sympathetic neurons in culture.
Topics: Aging; Animals; Culture Techniques; Ganglia, Sympathetic; Neuronal Plasticity; Neurons; Rats; Substance P; Tetrodotoxin; Veratridine | 1984 |
Developmental changes of tachykinins in the hypothalamus and anterior pituitary of female Siberian hamsters from prepuberty to adulthood.
Topics: Aging; Animals; Body Weight; Circadian Rhythm; Cricetinae; Darkness; Female; Hypothalamus; Light; Neurokinin A; Organ Size; Ovary; Phodopus; Pituitary Gland, Anterior; Rats; Sexual Maturation; Species Specificity; Substance P; Uterus | 1995 |
Substance P-immunoreactive neurons of the bovine forestomach mucosa: their presumptive role in a sensory mechanism.
Topics: Aging; Animals; Cattle; Gastric Mucosa; Nerve Fibers; Neurons; Omasum; Reticulum; Rumen; Sensation; Substance P | 1993 |
Relative contribution of sympathetic and sensory nerves to thermal nociception and tissue trophism in rats.
Topics: Aging; Animals; Animals, Newborn; Capsaicin; Female; Hot Temperature; Male; Nervous System Physiological Phenomena; Nociceptors; Oxidopamine; Radioimmunoassay; Rats; Rats, Wistar; Sensation; Sensory Thresholds; Skin; Substance P; Sympathetic Nervous System | 1993 |
The serotoninergic bulbospinal system and brainstem-spinal cord content of serotonin-, TRH-, and substance P-like immunoreactivity in the aged rat with special reference to the spinal cord motor nucleus.
Topics: Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Axons; Brain Stem; Fluorescent Antibody Technique; Galanin; Gene Expression; Hydroxyindoleacetic Acid; Immunohistochemistry; In Situ Hybridization; Male; Medulla Oblongata; Models, Neurological; Motor Neurons; Nerve Degeneration; Nerve Fibers; Peptides; Protein Precursors; Raphe Nuclei; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Spinal Cord; Substance P; Tachykinins; Thyrotropin-Releasing Hormone | 1993 |
Neurochemical and molecular biological aspects on the resetting of the arterial chemoreceptors in the newborn rat.
Topics: Aging; Animals; Animals, Newborn; Arteries; Carotid Body; Chemoreceptor Cells; Fetus; Gene Expression; Nodose Ganglion; Oligonucleotide Probes; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Tachykinins; Tyrosine 3-Monooxygenase | 1993 |
Ontogeny of the distribution of tachykinins in rat cerebral cortex: immunocytochemistry and in situ hybridization histochemistry.
Topics: Aging; Animals; Cerebral Cortex; Histocytochemistry; Immunohistochemistry; In Situ Hybridization; Neurokinin B; Protein Precursors; Rats; Rats, Sprague-Dawley; Substance P; Tachykinins; Tissue Distribution | 1994 |
Substance P immunohistochemical study of the sensory innervation of normal subchondral bone in the equine metacarpophalangeal joint.
Topics: Aging; Animals; Bone Development; Calcification, Physiologic; Forelimb; Horses; Immune Sera; Immunoenzyme Techniques; Immunohistochemistry; Joints; Ligaments; Nerve Fibers; Neurons, Afferent; Rabbits; Substance P; Synovial Membrane | 1994 |
Effects of ageing on tachykinin function in the basal ganglia.
Topics: Aging; Analysis of Variance; Animals; Basal Ganglia; Grooming; Infusions, Parenteral; Male; Motor Activity; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Stereotyped Behavior; Substance P; Substantia Nigra; Tachykinins; Ventral Tegmental Area | 1993 |
Ontogeny of neuropeptides in the rat urinary bladder.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Male; Neuropeptide Y; Neuropeptides; Organ Size; Rats; Rats, Sprague-Dawley; Substance P; Urinary Bladder; Vasoactive Intestinal Peptide | 1994 |
Substance P-like immunoreactivity in the hypothalamic suprachiasmatic nucleus of Phodopus sungorus--relation to daytime, photoperiod, sex and age.
Topics: Aging; Animals; Circadian Rhythm; Cricetinae; Darkness; Female; Immunohistochemistry; Light; Male; Neurons; Phodopus; Sex Factors; Substance P; Suprachiasmatic Nucleus; Time Factors | 1994 |
Neuropeptide expression by newborn and adult rat sensory neurons in culture: effects of nerve growth factor and other neurotrophic factors.
Topics: Aging; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Cell Survival; Cells, Cultured; Ciliary Neurotrophic Factor; Dose-Response Relationship, Drug; Drug Interactions; Ganglia, Spinal; Gene Expression; Growth Inhibitors; Interleukin-6; Kinetics; Leukemia Inhibitory Factor; Lymphokines; Nerve Growth Factors; Nerve Tissue Proteins; Neurons, Afferent; Neuropeptides; Neurotrophin 3; Rats; Rats, Wistar; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1994 |
Immunohistochemical evidence for the presence of nerve fibres with substance P- or calcitonin gene-related peptide-like immunoreactivity in the proliferating epithelium in the developing teeth of rats.
Topics: Aging; Ameloblasts; Animals; Calcitonin Gene-Related Peptide; Cell Division; Connective Tissue; Connective Tissue Cells; Epithelial Cells; Epithelium; Female; Gingiva; Immunohistochemistry; Male; Molar; Nerve Fibers; Odontogenesis; Rats; Rats, Wistar; Substance P; Tooth Eruption; Tooth Germ | 1994 |
Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Triphosphate; Aging; Animals; Azides; Biogenic Amines; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Functional Laterality; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Homovanillic Acid; Injections, Intraperitoneal; Lactates; Magnetic Resonance Imaging; Male; Microinjections; NADPH Dehydrogenase; Neurons; Neuropeptide Y; Neuropeptides; Neurotoxins; Oxidative Phosphorylation; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium Azide; Somatostatin; Substance P | 1994 |
Chronic administration of neurokinin SP improves maze performance in aged Rattus norvegicus.
Topics: Aging; Animals; Brain; Dose-Response Relationship, Drug; Escape Reaction; Injections, Intraperitoneal; Male; Maze Learning; Mental Recall; Motor Skills; Rats; Rats, Wistar; Substance P | 1994 |
Substance P-induced contraction of airway smooth muscle in young and adult rabbits. Effects of epithelium removal and neutral endopeptidase inhibition.
Topics: Aging; Animals; Bronchi; Epithelium; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Neprilysin; Rabbits; Substance P | 1995 |
GAP-43 persists in adulthood and coexists with SP and CGRP in human trigeminal sensory neurones.
Topics: Adult; Aged; Aging; Calcitonin Gene-Related Peptide; Female; Fetus; GAP-43 Protein; Growth Substances; Humans; Infant; Infant, Newborn; Male; Membrane Glycoproteins; Middle Aged; Nerve Tissue Proteins; Neurons; Substance P; Trigeminal Ganglion; Trigeminal Nuclei | 1994 |
Effect of neonatal hypoxia-ischemia on nigro-striatal dopamine receptors and on striatal neuropeptide Y, dynorphin A and substance P concentrations in rats.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Ischemia; Corpus Striatum; Dynorphins; Female; Functional Laterality; Hypoxia, Brain; Neuropeptide Y; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance P; Substantia Nigra | 1994 |
Calcitonin gene-related peptide (CGRP) and its effects on protein release in vitro in the developing submandibular gland of the rat.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Carbachol; Female; Immunohistochemistry; Male; Nerve Fibers; Neurokinin A; Neurons; Peroxidase; Proteins; Rats; Rats, Wistar; Submandibular Gland; Substance P; Superior Cervical Ganglion; Trigeminal Ganglion | 1995 |
Age-dependent mechanism in guinea pig bronchoconstriction induced by exsanguination.
Topics: Aging; Animals; Antioxidants; Body Weight; Bronchoconstriction; Catalase; Endopeptidases; Free Radicals; Guinea Pigs; Male; Respiratory Function Tests; Substance P; Tachykinins | 1995 |
Effect of a novel prolyl endopeptidase inhibitor, JTP-4819, on prolyl endopeptidase activity and substance P- and arginine-vasopressin-like immunoreactivity in the brains of aged rats.
Topics: Aging; Animals; Arginine Vasopressin; Cerebral Cortex; Diterpenes; Hippocampus; Immunoenzyme Techniques; Male; Phorbol Esters; Prolyl Oligopeptidases; Pyrrolidines; Rats; Rats, Inbred F344; Rats, Wistar; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P | 1995 |
Peptidergic neurons of subcortical white matter in aging and Alzheimer's brain.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cholecystokinin; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neurons; Neuropeptide Y; Neuropeptides; Somatostatin; Substance P; Visual Cortex | 1995 |
Attenuation of tachykinin-induced airflow obstruction and microvascular leakage in immature airways.
Topics: Aging; Airway Obstruction; Airway Resistance; Animals; Blood Pressure; Bronchoconstriction; Capillary Permeability; Evans Blue; Glycopeptides; Guinea Pigs; Lung; Male; Neprilysin; Neurokinin A; Pulmonary Ventilation; Substance P | 1993 |
Age-related respiratory responses to substance P in normal sheep.
Topics: Aging; Animals; Female; Respiration; Sheep; Substance P | 1993 |
Neurochemical development of the raphe after continuous prenatal cocaine exposure.
Topics: Aging; Animals; Animals, Newborn; Cocaine; Embryonic and Fetal Development; Female; Fetus; Pregnancy; Prenatal Exposure Delayed Effects; Protein Precursors; Raphe Nuclei; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Tachykinins; Tryptophan Hydroxylase | 1993 |
The development of non-retinal afferent projections to the frog optic tectum and the substance P immunoreactivity of tectal connections.
Topics: Afferent Pathways; Aging; Animals; Axonal Transport; Brain; Functional Laterality; Horseradish Peroxidase; Immunohistochemistry; Metamorphosis, Biological; Microscopy, Fluorescence; Rana pipiens; Retina; Rhodamines; Sexual Maturation; Substance P; Superior Colliculi | 1993 |
Effects of administration of ciliary neurotrophic factor on normal motor and sensory peripheral nerves in vivo.
Topics: Aging; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Ciliary Neurotrophic Factor; Female; Ganglia, Spinal; Humans; Motor Neurons; Nerve Growth Factors; Nerve Tissue Proteins; Neural Conduction; Neurons, Afferent; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Substance P; Tibial Nerve | 1993 |
Synergistic regulation of vasoactive intestinal polypeptide expression by cyclic AMP and calcium in newborn but not adult rat sensory neurons in culture.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Animals, Newborn; Axons; Calcitonin Gene-Related Peptide; Calcium; Colforsin; Cyclic AMP; Female; Ganglia, Spinal; Immunohistochemistry; Male; Nerve Growth Factors; Neurons, Afferent; Rats; Rats, Wistar; Signal Transduction; Substance P; Vasoactive Intestinal Peptide | 1993 |
Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate.
Topics: Adenosine Triphosphate; Aging; Animals; Corpus Striatum; Dizocilpine Maleate; gamma-Aminobutyric Acid; Lactates; Lactic Acid; Magnetic Resonance Imaging; Male; Malonates; Mitochondria; Neurotoxins; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Somatostatin; Substance P | 1993 |
Prenatal cocaine increases striatal serotonin innervation without altering the patch/matrix organization of intrinsic cell types.
Topics: Acetylcholinesterase; Aging; Animals; Calbindins; Cocaine; Corpus Striatum; Enkephalins; Female; Immunohistochemistry; Male; NADPH Dehydrogenase; Neurons, Afferent; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Serotonin; Substance P; Substantia Nigra | 1993 |
Distribution of GAP-43 in relation to CGRP and synaptic vesicle markers in rat skeletal muscles during development.
Topics: Aging; Animals; Biomarkers; Calcitonin Gene-Related Peptide; Female; GAP-43 Protein; Immunohistochemistry; Male; Membrane Glycoproteins; Motor Endplate; Muscle Development; Muscles; Nerve Endings; Nerve Tissue Proteins; Neurofilament Proteins; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Substance P; Synapsins; Synaptic Vesicles; Synaptophysin | 1993 |
Comparison of silver stainings and immunohistology for the detection of neurofibrillary tangles and extracellular cerebral amyloid in paraffin sections.
Topics: Aging; Amyloid; Analysis of Variance; Brain; Brain Chemistry; Costs and Cost Analysis; Extracellular Space; Humans; Immunohistochemistry; Nerve Tissue Proteins; Neurofibrillary Tangles; Paraffin Embedding; Silver Staining; Substance P; tau Proteins | 1993 |
Ontogeny of sensory nerves in the developing skeleton.
Topics: Aging; Animals; Animals, Newborn; Bone and Bones; Bone Development; Calcitonin Gene-Related Peptide; Embryonic and Fetal Development; Immunohistochemistry; Nervous System; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Substance P | 1995 |
Regulation by nerve growth factor of neuropeptide phenotypes in primary cultured sensory neurons prepared from aged as well as adult mice.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Immunoenzyme Techniques; Male; Mice; Mice, Inbred CBA; Nerve Growth Factors; Neurons, Afferent; Neuropeptide Y; Neuropeptides; Phenotype; Somatostatin; Substance P | 1995 |
The effect of haloperidol on met-enkephalin, beta-endorphin, cholecystokinin and substance P in the pituitary, the hypothalamus and the striatum of rats during aging.
Topics: Aging; Animals; beta-Endorphin; Cholecystokinin; Corpus Striatum; Enkephalin, Methionine; Haloperidol; Hypothalamus; Male; Pituitary Gland; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Substance P | 1995 |
Postnatal development and aging of the rat ventral root L5: electron microscopic and immunohistochemical studies.
Topics: Adrenergic Fibers; Aging; Animals; Animals, Newborn; Axons; Calcitonin Gene-Related Peptide; Immunohistochemistry; Microscopy, Electron; Myelin Sheath; Neurons; Rats; Rats, Sprague-Dawley; Spinal Nerve Roots; Substance P; Tyrosine 3-Monooxygenase | 1996 |
Sensory peptides as neuromodulators of wound healing in aged rats.
Topics: Aging; Animals; Blister; Burns; Calcitonin Gene-Related Peptide; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Skin; Substance P; Vasodilation; Wound Healing | 1996 |
Origin of interstitial cells of Cajal in the mouse intestine.
Topics: Aging; Animals; Calbindin 2; Embryonic and Fetal Development; Female; Fetal Tissue Transplantation; Gestational Age; Immunohistochemistry; Intestines; Kidney; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Development; Muscle, Smooth; Nerve Tissue Proteins; Neural Crest; Neuroglia; Neurons; Phosphopyruvate Hydratase; Pregnancy; Proto-Oncogene Proteins c-kit; Receptors, Neurokinin-1; S100 Calcium Binding Protein G; Substance P; Transplantation, Heterotopic | 1996 |
Age-related changes in calcitonin gene-related peptide and substance P in renal afferent nerve soma in the rat. Association with afferent renal nerve activity.
Topics: Afferent Pathways; Aging; Animals; Calcitonin Gene-Related Peptide; Chemoreceptor Cells; Immunohistochemistry; Kidney; Male; Neurons; Rats; Rats, Sprague-Dawley; Substance P | 1996 |
The generation of neuronal heterogeneity in a rat sensory ganglion.
Topics: 3T3 Cells; Aging; Animals; Calcitonin Gene-Related Peptide; Cell Line; Cells, Cultured; Coculture Techniques; Embryonic and Fetal Development; Ganglia, Spinal; Gene Expression Regulation, Developmental; Gestational Age; Mice; Muscle, Skeletal; Muscle, Smooth; Neurofilament Proteins; Neurons; Neuropeptides; Rats; Rats, Sprague-Dawley; Skin; Substance P; Transcription, Genetic | 1997 |
Curtailed respiration by repeated vs. isolated hypoxia in maturing piglets is unrelated to NTS ME or SP levels.
Topics: Aging; Animals; Animals, Newborn; Enkephalin, Methionine; Female; Hypoxia; Male; Recurrence; Respiration; Solitary Nucleus; Substance P; Swine; Swine, Miniature | 1997 |
Immunohistochemical colocalization of serotonin, substance P and Met-enkephalin-Arg6-Gly7-Leu8 in the endocrine cells of the ruminant duodenum.
Topics: Aging; Animals; Cattle; Duodenum; Enkephalin, Methionine; Enterochromaffin Cells; Goats; Immunohistochemistry; Intestinal Mucosa; Serotonin; Sheep; Species Specificity; Substance P | 1998 |
Comparison of [125I]-bolton-hunter substance P binding in young and aged rat spinal cord.
Topics: Aging; Animals; Autoradiography; Binding Sites; Iodine Radioisotopes; Lumbosacral Region; Male; Rats; Rats, Wistar; Receptors, Neurokinin-1; Spinal Cord; Substance P; Succinimides | 1998 |
The autonomous innervation of the porcine testis in the period from birth to adulthood.
Topics: Acetylcholinesterase; Aging; Animals; Animals, Newborn; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Immunohistochemistry; Male; Neuropeptide Y; Neuropeptides; Substance P; Swine; Testis; Vasoactive Intestinal Peptide | 1998 |
Evidence for purinergic neurotransmission in the urinary bladder of pithed rats.
Topics: Adenosine Triphosphate; Adrenergic Antagonists; Aging; Animals; Atropine; Blood Pressure; Decerebrate State; Electric Stimulation; Female; Ganglionic Blockers; Muscarinic Antagonists; Muscle, Smooth; Pressure; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Purinergic; Spinal Nerves; Substance P; Synaptic Transmission; Urinary Bladder | 1998 |
The effects of age on the overall population and on sub-populations of myenteric neurons in the rat small intestine.
Topics: Aging; Animals; Biomarkers; Choline O-Acetyltransferase; Dihydrolipoamide Dehydrogenase; Enkephalin, Methionine; Ileum; Immunohistochemistry; Intestine, Small; Myenteric Plexus; Neurons; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Somatostatin; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide | 1998 |
Innervation of the equine mature and immature proximal sesamoid bone by calcitonin gene-related peptide and substance P-containing nerves.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Female; Forelimb; Horses; Immunoenzyme Techniques; Male; Nerve Fibers; Rabbits; Sesamoid Bones; Substance P; Sympathetic Nervous System; Tyrosine 3-Monooxygenase | 1998 |
Mechanism for substance P-induced relaxation of precontracted airway smooth muscle during development.
Topics: Aging; Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Muscle Development; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Substance P; Trachea | 1999 |
Increase in fiber density for immunoreactive serotonin, substance P, enkephalin and thyrotropin-releasing hormone occurs during the early presymptomatic period of motoneuron disease in Wobbler mouse spinal cord ventral horn.
Topics: Aging; Animals; Behavior, Animal; Cell Count; Enkephalins; Female; Immunohistochemistry; Male; Mice; Mice, Neurologic Mutants; Motor Neuron Disease; Nerve Fibers; Serotonin; Spinal Cord; Substance P; Thyrotropin-Releasing Hormone | 1999 |
Depletion of cutaneous peptidergic innervation in HIV-associated xerosis.
Topics: Adult; Aging; Anti-HIV Agents; Calcitonin Gene-Related Peptide; Disease Progression; Female; HIV Infections; Humans; Male; Middle Aged; Nervous System Physiological Phenomena; Peptides; Protein Precursors; Skin; Skin Diseases; Substance P; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide | 1999 |
Decreased neuropeptide content in the spinal cord of aged rats: the effect of GM1 ganglioside.
Topics: Aging; Animals; Dynorphins; Enkephalin, Methionine; G(M1) Ganglioside; Ganglia, Spinal; Male; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Tissue Distribution | 1999 |
Altered respiratory response to substance P and reduced NK1 receptor binding in the nucleus of the solitary tract of aged rats.
Topics: Aging; Animals; Autoradiography; Iodine Radioisotopes; Male; Radioligand Assay; Rats; Rats, Wistar; Receptors, Neurokinin-1; Respiration; Solitary Nucleus; Substance P; Succinimides | 1999 |
Substance P and central respiratory activity: a comparative in vitro study on foetal and newborn rat.
Topics: Aging; Animals; Animals, Newborn; Brain Stem; Embryonic and Fetal Development; Fetus; Gestational Age; Membrane Potentials; Motor Neurons; Naloxone; Patch-Clamp Techniques; Phrenic Nerve; Rats; Respiratory Mechanics; Spinal Cord; Substance P | 1999 |
Pharmacologic characteristics of non-prostanoid, non-nitric oxide mediated and endothelium-dependent relaxation of guinea-pig aorta in response to substance P.
Topics: Aging; Animals; Animals, Newborn; Aorta, Thoracic; Endothelium, Vascular; Epoprostenol; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Norepinephrine; Potassium Channel Blockers; Substance P | 1999 |
Postnatal development of NK1, NK2, and NK3 neurokinin receptors expression in the rat retina.
Topics: Aging; Animals; Cell Differentiation; Cell Size; Gene Expression Regulation, Developmental; Immune Sera; Immunohistochemistry; Neurons; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Retina; Substance P; Visual Pathways | 1999 |
A transient geniculo-extrastriate pathway in macaques? Implications for 'blindsight'.
Topics: Aging; Animals; Blindness; Calcitonin Gene-Related Peptide; Female; Geniculate Bodies; Macaca mulatta; Neurokinin A; Substance P; Visual Cortex; Visual Pathways | 1999 |
Influence of ageing on vasomotor responses of human epicardial coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Aged, 80 and over; Aging; Calcitonin Gene-Related Peptide; Cardiomyopathies; Coronary Vessels; Dose-Response Relationship, Drug; Endothelins; Humans; In Vitro Techniques; Middle Aged; Norepinephrine; Substance P; Vasoactive Intestinal Peptide; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasomotor System | 2000 |
Immunohistochemical localization of neuropeptides in bovine pancreas.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Cattle; Enkephalin, Methionine; Female; Galanin; Immunohistochemistry; Islets of Langerhans; Neuropeptide Y; Neuropeptides; Pancreas; Substance P; Vasoactive Intestinal Peptide | 2000 |
Distribution of capsaicin-sensitive substance P- and calcitonin gene-related peptide-immunoreactive nerves in bovine respiratory tract.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cattle; Female; Immunohistochemistry; Nerve Fibers; Respiratory Mucosa; Respiratory System; Substance P | 2000 |
Modulation of inflammation by reactive oxygen species: implications for aging and tissue repair.
Topics: Aging; Animals; Antioxidants; Blister; Blood Flow Velocity; Burns; Inflammation; Laser-Doppler Flowmetry; Male; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Substance P; Suction; Wound Healing | 2001 |
[Effect of Gengnianjian on up regulated estrogen receptor mRNA to substance P and beta-endorphin in hypothalamus of aging female rats].
Topics: Aging; Animals; beta-Endorphin; Drugs, Chinese Herbal; Estradiol; Female; Hypothalamus; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; RNA, Messenger; Substance P; Up-Regulation | 1998 |
Differential involvement of conotoxin-sensitive mechanisms in neurogenic vasodilatation responses: effects of age.
Topics: Aging; Analysis of Variance; Animals; Blister; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Calcium Channels; Electric Stimulation; Laser-Doppler Flowmetry; Male; Models, Animal; Muscle, Smooth; Neuropeptides; omega-Conotoxins; Rats; Rats, Sprague-Dawley; Reference Values; Sciatic Nerve; Sensory Receptor Cells; Skin; Substance P; Vasodilation; Wound Healing | 2001 |
Developmental shift of vanilloid receptor 1 (VR1) terminals into deeper regions of the superficial dorsal horn: correlation with a shift from TrkA to Ret expression by dorsal root ganglion neurons.
Topics: Afferent Pathways; Aging; Animals; Animals, Newborn; Binding Sites; Capsaicin; Drosophila Proteins; Fluorescent Antibody Technique; Ganglia, Spinal; Hyperalgesia; Lectins; Microscopy, Confocal; Pain Measurement; Pain Threshold; Posterior Horn Cells; Presynaptic Terminals; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Drug; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Skin; Substance P | 2001 |
Somatostatin- and Substance P-ergic neurons and Glial cell line-derived neurotrophic factor in the human archicortex.
Topics: Adult; Aging; Cell Differentiation; Fetus; Glial Cell Line-Derived Neurotrophic Factor; Hippocampus; Humans; Immunohistochemistry; Infant, Newborn; Nerve Growth Factors; Nerve Tissue Proteins; Presynaptic Terminals; Pyramidal Cells; Somatostatin; Substance P | 2001 |
Substance P immunoreactivity in the enteric nervous system in Rett syndrome.
Topics: Adolescent; Adult; Aging; Catecholamines; Child; Child, Preschool; Digestive System; Enteric Nervous System; Female; Gastrointestinal Diseases; Humans; Immunohistochemistry; Infant; Infant, Newborn; Neurons; Rett Syndrome; Substance P; Sympathetic Fibers, Postganglionic; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 2001 |
Evidence for a neuropathic contribution to the development of spontaneous knee osteoarthrosis in a mouse model.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Immunohistochemistry; Knee Joint; Male; Mechanoreceptors; Mice; Mice, Inbred C57BL; Neuropeptides; Osteoarthritis, Knee; Risk Assessment; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Substance P | 2002 |
Reciprocal age-related changes in GAP-43/B-50, substance P and calcitonin gene-related peptide (CGRP) expression in rat primary sensory neurones and their terminals in the dorsal horn of the spinal cord and subintima of the knee synovium.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Cell Count; Down-Regulation; Ganglia, Spinal; GAP-43 Protein; Immunohistochemistry; Knee Joint; Male; Neurotransmitter Agents; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Substance P; Synovial Membrane; Up-Regulation | 2002 |
Age differences in neurokinin A and substance P from the hypothalamus, pituitary, pineal gland, and striatum of the rat. Effect of exogenous melatonin.
Topics: Aging; Animals; Female; Hypothalamus; Injections, Subcutaneous; Melatonin; Neostriatum; Neurokinin A; Pineal Gland; Pituitary Gland; Rats; Rats, Wistar; Substance P | 2002 |
Substance P in rat CNS and duodenum during development.
Topics: Aging; Animals; Brain; Brain Stem; Caudate Nucleus; Cerebral Cortex; Duodenum; Female; Hypothalamus; Neural Pathways; Neurons; Olfactory Bulb; Pregnancy; Radioimmunoassay; Rats; Spinal Cord; Substance P; Substantia Nigra | 1979 |
Conditioned-reflex learning of normal juvenile and adult rats exposed to action of substance P and of an SP analogue.
Topics: Aging; Animals; Blood Pressure; Conditioning, Classical; Male; Motor Activity; Rats; Substance P | 1979 |
Immunohistochemical study on development of serotonin-, substance P-, and enkephalin-positive fibers in the rat spinal motor nucleus.
Topics: Aging; Animals; Enkephalins; Female; Immunohistochemistry; Medulla Oblongata; Nerve Fibers; Neural Pathways; Pregnancy; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Spinal Cord; Substance P | 1992 |
Postnatal changes in development of serotonin-, neuropeptide Y-, Leu-enkephalin- and substance P- terminals in the rat locus coeruleus; a quantitative immunohistochemical study.
Topics: Aging; Animals; Animals, Newborn; Enkephalin, Leucine; Female; Immunoenzyme Techniques; Immunohistochemistry; Locus Coeruleus; Male; Microscopy, Electron; Nerve Endings; Neurons, Afferent; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Serotonin; Substance P | 1992 |
Neonatal sciatic nerve section results in thiamine monophosphate but not substance P or calcitonin gene-related peptide depletion from the terminal field in the dorsal horn of the rat: the role of collateral sprouting.
Topics: Aging; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Immunohistochemistry; Nerve Endings; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Substance P; Thiamine Monophosphate | 1992 |
Effect of ageing on responses of nerve fibres to pulpal inflammation in rat molars analysed by quantitative immunocytochemistry.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Dental Pulp; Dentin; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Molar; Nerve Fibers; Pulpitis; Rats; Rats, Inbred F344; Receptors, Nerve Growth Factor; Substance P; Tooth Root | 1992 |
Substance P and NMDA receptor-mediated slow potentials in neonatal rat spinal cord: age-related changes.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Aging; Analgesics; Animals; Animals, Newborn; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Substance P; Synaptic Transmission; Tetraethylammonium Compounds | 1992 |
Postnatal development of sympathetic and sensory innervation of the rhesus monkey ovary.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Female; Fluorescent Antibody Technique; Macaca mulatta; Neuropeptide Y; Ovary; Parasympathetic Nervous System; Substance P; Sympathetic Nervous System; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 1992 |
Decrease of enkephalins in cerebellum during Wobbler mouse motoneuron disease.
Topics: Aging; Animals; Cerebellum; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Mice; Mice, Neurologic Mutants; Motor Neuron Disease; Substance P; Thyrotropin-Releasing Hormone | 1992 |
Neonatal nerve growth factor treatment alters the preganglionic innervation pattern of rat superior cervical ganglion.
Topics: Aging; Animals; Animals, Newborn; Axons; Calcitonin Gene-Related Peptide; Choline O-Acetyltransferase; Ganglia, Sympathetic; Nerve Endings; Nerve Growth Factors; Neurons; Rats; Rats, Wistar; Substance P; Tyrosine 3-Monooxygenase | 1992 |
The ontogeny and distribution of neuropeptides in the human fetal and infant esophagus.
Topics: Aging; Bombesin; Embryonic and Fetal Development; Enkephalin, Methionine; Esophagus; Fetus; Galanin; Gestational Age; Glial Fibrillary Acidic Protein; Humans; Image Processing, Computer-Assisted; Infant, Newborn; Neuropeptide Y; Neuropeptides; Peptide Biosynthesis; Regression Analysis; Somatostatin; Substance P; Synaptophysin; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide | 1992 |
Postnatal changes in the substance P receptor on rabbit gastric smooth muscle.
Topics: Aging; Animals; Animals, Newborn; Binding, Competitive; Dose-Response Relationship, Drug; Gastric Mucosa; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Osmolar Concentration; Rabbits; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Stomach; Substance P; Tachykinins; Time Factors | 1992 |
Plasticity of the serotonergic innervation of the dorsal horn of the rat spinal cord following neonatal capsaicin treatment.
Topics: Aging; Animals; Animals, Newborn; Axons; Calcitonin Gene-Related Peptide; Capsaicin; Immunohistochemistry; Microscopy, Electron; Nerve Fibers; Neurons, Afferent; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P | 1992 |
Distribution of neuropeptide Y, substance P, and choline acetyltransferase in the developing visual system of the pigeon and effects of unilateral retina removal.
Topics: Aging; Animals; Brain; Choline O-Acetyltransferase; Columbidae; Embryo, Nonmammalian; Functional Laterality; Immunohistochemistry; Neuropeptide Y; Organ Specificity; Retina; Substance P; Visual Pathways | 1992 |
Effects of age and streptozotocin-induced diabetes on contents and effects of substance P and vasoactive intestinal polypeptide in the lower urinary tract of the rat.
Topics: Aging; Animals; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Rats; Rats, Inbred Strains; Substance P; Urethra; Urinary Bladder; Urinary Tract; Vasoactive Intestinal Peptide | 1992 |
Regulation of adenohypophyseal messenger RNAs in female rats by age, hypothyroidism, estradiol and neonatal androgenization.
Topics: Aging; Analysis of Variance; Animals; Estradiol; Female; Hypothyroidism; Luteinizing Hormone; Organ Size; Pituitary Gland, Anterior; Prolactin; Protein Precursors; Radioimmunoassay; Rats; RNA, Messenger; Substance P; Tachykinins; Testosterone; Thyrotropin | 1992 |
The development of substance P-like immunoreactivity in the goldfish brain.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Stem; Cerebral Ventricles; Diencephalon; Fertilization; Goldfish; Immunoenzyme Techniques; Larva; Medulla Oblongata; Olfactory Bulb; Substance P; Superior Colliculi; Vagus Nerve | 1992 |
Effect of maturation on histamine-induced airflow obstruction and airway microvascular leakage in guinea pig airways.
Topics: Aging; Airway Obstruction; Airway Resistance; Animals; Blood Pressure; Bronchi; Capillary Permeability; Dose-Response Relationship, Drug; Evans Blue; Guinea Pigs; Histamine; Lung; Male; Substance P; Trachea | 1992 |
Intracellular pH changes induced by exposure to weak acids and bases in submandibular cells of early postnatal rats.
Topics: Acetylcholine; Aging; Amiloride; Ammonium Chloride; Animals; Bumetanide; Butyrates; Butyric Acid; Cells, Cultured; Hydrogen-Ion Concentration; Ionomycin; Male; Rats; Rats, Sprague-Dawley; Submandibular Gland; Substance P; Time Factors | 1992 |
Substance P-like immunoreactivity in the human trigeminal ganglion.
Topics: Aged; Aging; Humans; Infant, Newborn; Infant, Premature; Substance P; Trigeminal Ganglion | 1990 |
Neuropeptide substance P improves water maze performance in aged rats.
Topics: Aging; Animals; Injections, Intraperitoneal; Learning; Male; Psychomotor Performance; Rats; Rats, Inbred Strains; Space Perception; Substance P | 1990 |
Neuroaxonal dystrophy in aging human sympathetic ganglia.
Topics: Adult; Aged; Aging; Autopsy; Axons; Enkephalin, Methionine; Ganglia, Sympathetic; Gastrin-Releasing Peptide; Humans; Immunohistochemistry; Microscopy, Electron; Middle Aged; Nervous System Diseases; Neurons; Neuropeptide Y; Peptides; Substance P; Synapses; Time Factors; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 1990 |
Postnatal development of striatal neurotensin immunoreactivity in relation to clusters of substance P immunoreactive neurons and the "dopamine islands" in the rat.
Topics: Aging; Animals; Corpus Striatum; Dopamine; Immunohistochemistry; Neurotensin; Rats; Rats, Inbred Strains; Substance P; Tyrosine 3-Monooxygenase | 1990 |
Measurement of neuropeptides in the brain and spinal cord of Wobbler mouse: a model for motoneuron disease.
Topics: Aging; Animals; Brain; Brain Chemistry; Disease Models, Animal; Enkephalin, Leucine; Enkephalin, Methionine; Mice; Mice, Neurologic Mutants; Motor Neurons; Neuromuscular Diseases; Neuropeptides; Somatostatin; Spinal Cord; Substance P; Thyrotropin-Releasing Hormone | 1990 |
Development of substance P, Leu-enkephalin and serotonin profiles in the lateral geniculate nuclear complex of albino rat.
Topics: Aging; Animals; Enkephalin, Leucine; Fetus; Geniculate Bodies; Rats; Rats, Inbred Strains; Serotonin; Substance P | 1990 |
Development of striatal compartmentalization following pre- or postnatal dopamine depletion.
Topics: Acetylcholinesterase; Aging; Animals; Biomarkers; Corpus Striatum; Dopamine Antagonists; Female; Gestational Age; Hydroxydopamines; Oxidopamine; Pregnancy; Rats; Rats, Inbred Strains; Reference Values; Substance P; Substantia Nigra; Tyrosine 3-Monooxygenase | 1991 |
Neuroendocrine cells of the human lung express substance-P-like immunoreactivity.
Topics: Adult; Aged; Aging; Child; Cytoplasm; Epithelial Cells; Epithelium; Humans; Immunohistochemistry; Infant; Infant, Newborn; Lung; Neurosecretory Systems; Substance P | 1990 |
Anatomical distribution of substance P-immunoreactive neurons in human brainstem during the first postnatal year.
Topics: Aging; Brain Stem; Humans; Immunoenzyme Techniques; Infant; Infant, Newborn; Neurons; Organ Specificity; Substance P; Trigeminal Nucleus, Spinal | 1991 |
Postnatal development of neurogenic inflammation in the rat.
Topics: Aging; Animals; Animals, Newborn; Bradykinin; Dermatitis; Histamine; Injections, Intradermal; Nervous System Physiological Phenomena; Plasma; Rats; Rats, Inbred Strains; Skin; Substance P | 1991 |
Neuropeptides of the primary sensory neurones in rat skin: an ontogenic study.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Female; Male; Neurokinin A; Neurons, Afferent; Peptide PHI; Rats; Rats, Inbred Strains; Skin; Substance P | 1991 |
[Abnormalities in cough reflex].
Topics: Aging; Bronchitis; Cough; Female; Humans; Male; Neprilysin; Pneumonia, Aspiration; Reflex; Substance P | 1991 |
Neuropeptide levels in the basal ganglia of aged common marmosets following prolonged treatment with MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Basal Ganglia; Biogenic Monoamines; Callithrix; Caudate Nucleus; Dopamine; Enkephalin, Leucine; Enkephalin, Methionine; Female; Globus Pallidus; Homovanillic Acid; Male; Neuropeptides; Neurotensin; Putamen; Reference Values; Sincalide; Substance P | 1991 |
Responses of coronary arteries to neurotransmitters: changes with sexual maturity in the female rabbit.
Topics: Acetylcholine; Aging; Animals; Body Weight; Calcitonin Gene-Related Peptide; Coronary Vessels; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Neurotransmitter Agents; Norepinephrine; Potassium Chloride; Rabbits; Serotonin; Sexual Maturation; Substance P; Vasoactive Intestinal Peptide | 1991 |
Developmental and hormonal regulation of the sex difference in preprotachykinin gene expression in rat anterior pituitaries.
Topics: Aging; Animals; Estradiol; Female; Gene Expression Regulation; Male; Neurokinin A; Orchiectomy; Pituitary Gland, Anterior; Protein Precursors; Rats; Reference Values; RNA, Messenger; Sex Characteristics; Substance P; Tachykinins; Testosterone; Thyroidectomy | 1991 |
Substance P-containing and calcitonin gene-related peptide-containing neurons in the human trigeminal ganglion. Immunohistochemical detection, morphometric characterization, and coexistence of peptides.
Topics: Adult; Aging; Calcitonin Gene-Related Peptide; Fetus; Humans; Infant, Newborn; Infant, Premature; Neurons; Substance P; Trigeminal Ganglion | 1991 |
Effects of ageing on nicotine-induced contraction and substance P-like materials release in guinea-pig bronchus.
Topics: Aging; Animals; Bronchi; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1991 |
A transitory population of substance P-like immunoreactive neurones in the developing cerebral cortex of the mouse.
Topics: Aging; Animals; Animals, Newborn; Antibodies, Monoclonal; Cerebral Cortex; Immunoenzyme Techniques; Mice; Neurons; Substance P; Time Factors | 1991 |
Abrogation of peripheral cholecystokinin-satiety in the capsaicin treated rat.
Topics: Aging; Animals; Animals, Newborn; Biological Transport; Capsaicin; Cholecystokinin; Fasting; Feeding Behavior; Insulin; Obesity; Rats; Rats, Inbred Strains; Satiation; Satiety Response; Somatostatin; Substance P; Vagus Nerve; Ventromedial Hypothalamic Nucleus | 1985 |
Effect of age on substance P levels in the rat mesenteric artery and vein.
Topics: Aging; Animals; Male; Mesenteric Arteries; Mesenteric Veins; Rats; Rats, Inbred F344; Substance P | 1985 |
Perivascular noradrenergic and peptide-containing nerves show different patterns of changes during development and ageing in the guinea-pig.
Topics: Aging; Animals; Arteries; Calcitonin Gene-Related Peptide; Carotid Arteries; Femoral Artery; Guinea Pigs; Male; Mesenteric Arteries; Nerve Tissue Proteins; Norepinephrine; Renal Artery; Substance P; Vasoactive Intestinal Peptide | 1986 |
Early development of tyrosine hydroxylase-like and substance P-like immunoreactivity in the human fetal retina.
Topics: Aging; Embryonic and Fetal Development; Humans; Infant; Infant, Newborn; Neurons; Retina; Substance P; Tyrosine 3-Monooxygenase | 1986 |
Ontogeny of substance P receptors in rat spinal cord: quantitative changes in receptor number and differential expression in specific loci.
Topics: Aging; Animals; Autoradiography; Iodine Radioisotopes; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Spinal Cord; Substance P | 1986 |
Alterations in substance P binding in brain nuclei of spontaneously hypertensive rats.
Topics: Aging; Animals; Autoradiography; Binding Sites; Blood Pressure; Brain; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Tissue Distribution | 1987 |
The ontogeny of vasoactive intestinal polypeptide-like and substance P-like immunoreactivity in the digestive tract of the sheep.
Topics: Aging; Animals; Animals, Newborn; Digestive System; Esophagus; Gallbladder; Gestational Age; Immunoassay; Myenteric Plexus; Pancreas; Sheep; Submandibular Gland; Substance P; Tissue Distribution; Vasoactive Intestinal Peptide | 1987 |
Effects of age on the axon reflex response to noxious chemical stimulation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Axons; Capsaicin; Humans; Middle Aged; Reflex; Skin; Stimulation, Chemical; Substance P | 1986 |
Further studies on the mechanisms of the tachykinin-induced activation of micturition reflex in rats: evidence for the involvement of the capsaicin-sensitive bladder mechanoreceptors.
Topics: Aging; Animals; Capsaicin; Diphenhydramine; Electric Stimulation; In Vitro Techniques; Indomethacin; Kassinin; Male; Mechanoreceptors; Neurokinin A; Neurokinin B; Neuropeptides; Oligopeptides; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin; Urinary Bladder; Urination | 1987 |
The human hippocampal formation and parahippocampal gyrus: localization of substance P-like immunoreactivity in newborn and adult post-mortem tissue.
Topics: Aged; Aging; Fluorescent Antibody Technique; Hippocampus; Histocytochemistry; Humans; Infant, Newborn; Middle Aged; Neurons; Substance P | 1987 |
Substance P-like immunoreactivity in capsaicin-sensitive structures of the rat thymus.
Topics: Aging; Animals; Capsaicin; Chromatography, High Pressure Liquid; Cricetinae; Female; Guinea Pigs; Hydroxydopamines; Kinetics; Male; Mice; Norepinephrine; Oxidopamine; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Species Specificity; Substance P; Thymus Gland | 1987 |
Prenatal influence of substance P on blood pressure and stress sensitivity of spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Body Weight; Female; Heart Rate; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred SHR; Sex Factors; Stress, Physiological; Substance P | 1987 |
Density of substance P, vasoactive intestinal polypeptide and somatostatin-containing nerve fibers in the ageing small intestine of the rats.
Topics: Aging; Animals; Female; Immunoenzyme Techniques; Intestine, Small; Rats; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 1987 |
Evidence for the presence of substance P-like immunoreactivity in the human cerebellum.
Topics: Aged; Aging; Cerebellum; Female; Fluorescent Antibody Technique; Humans; Infant, Newborn; Male; Substance P | 1988 |
Destruction by anti-NGF of autonomic, sudomotor neurones and subsequent hyperinnervation of the foot pad by sensory fibres.
Topics: Adrenergic Fibers; Aging; Animals; Animals, Newborn; Hindlimb; Hydroxydopamines; Immune Sera; Nerve Growth Factors; Neuronal Plasticity; Neurons, Afferent; Oxidopamine; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Sweat Glands; Vasoactive Intestinal Peptide | 1988 |
Evidence for the existence of three classes of neurokinin receptors in brain. Differential ontogeny of neurokinin-1, neurokinin-2 and neurokinin-3 binding sites in rat cerebral cortex.
Topics: Aging; Animals; Cerebral Cortex; Eledoisin; Female; Male; Neurokinin A; Neuropeptides; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1988 |
Distribution of substance P-immunoreactive structures in the developing cat carotid body.
Topics: Aging; Animals; Carotid Body; Cats; Immunohistochemistry; Substance P | 1988 |
Tachykinin binding sites in the interpeduncular nucleus of the rat: normal distribution, postnatal development and the effects of lesions.
Topics: Aging; Animals; Animals, Newborn; Eledoisin; Female; Male; Mesencephalon; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P; Succinimides; Thalamus | 1988 |
A developmental influence of substance P on its receptors.
Topics: Aging; Animals; Animals, Newborn; Brain; Injections, Subcutaneous; Rats; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Salivary Glands; Substance P | 1987 |
Increase in substance P levels in the lung of old rats.
Topics: Aging; Animals; Lung; Male; Organ Size; Rats; Rats, Inbred Strains; Substance P | 1988 |
Biochemical, anatomical and functional correlates of postnatal development of the capsaicin-sensitive innervation of the rat urinary bladder.
Topics: Acetylcholine; Aging; Animals; Capsaicin; Female; Male; Muscle Contraction; Neurons, Afferent; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1988 |
Development of substance P-containing neurons in the central nervous system in mice: an immunocytochemical study.
Topics: Aging; Animals; Brain; Embryonic and Fetal Development; Immunohistochemistry; Mice; Substance P | 1988 |
The postnatal ontogeny of substance P-immunoreactive fibers in the sympathetic preganglionic nuclei of the rat.
Topics: Aging; Animals; Autonomic Fibers, Preganglionic; Immunohistochemistry; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1988 |
Developmental alterations in thermal nociceptive threshold and the distribution of immunoreactive calcitonin gene-related peptide and substance P after neonatal administration of capsaicin in the rat.
Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Hot Temperature; Immunohistochemistry; Neuropeptides; Nociceptors; Rats; Rats, Inbred Strains; Sensory Thresholds; Spinal Cord; Substance P | 1989 |
Development of substance P- and vasoactive intestinal polypeptide-containing neurones in the rat stomach.
Topics: Aging; Animals; Animals, Newborn; Fetus; Fluorescent Antibody Technique; Gestational Age; Neurons; Rats; Rats, Inbred Strains; Reference Values; Stomach; Substance P; Vasoactive Intestinal Peptide | 1988 |
Developmental characteristics of substance P immunoreactivity within specific rabbit brainstem nuclei.
Topics: Aging; Animals; Brain Stem; Rabbits; Radioimmunoassay; Substance P | 1988 |
Ontogenesis of endocrine cells in the chicken intestine: an immunohistochemical study.
Topics: Aging; Animals; Cecum; Chick Embryo; Chickens; Cholecystokinin; Colon; Gastrins; Ileum; Motilin; Neuropeptides; Neurotensin; Somatostatin; Substance P | 1989 |
Effect of neonatal infraorbital nerve transection on substance P- and leucine enkephalin-like immunoreactivities in trigeminal subnucleus caudalis of the rat.
Topics: Aging; Animals; Animals, Newborn; Brain Stem; Denervation; Enkephalin, Leucine; Immunohistochemistry; Nervous System Physiological Phenomena; Orbit; Rats; Rats, Inbred Strains; Substance P; Tissue Distribution; Trigeminal Caudal Nucleus; Trigeminal Nucleus, Spinal | 1988 |
Regulation of nerve growth factor mRNA levels in developing rat heart ventricle is not altered by sympathectomy.
Topics: Aging; Animals; Female; Heart; Heart Ventricles; Hydroxydopamines; Male; Nerve Growth Factors; Neurons; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; RNA, Messenger; Substance P; Sympathectomy, Chemical; Sympathetic Nervous System | 1989 |
Ontogeny of substance P-containing neurons in relation to serotonin-containing neurons in the central nervous system of the mouse.
Topics: Aging; Animals; Central Nervous System; Embryonic and Fetal Development; Immunohistochemistry; Mice; Serotonin; Substance P | 1989 |
Death of some dorsal root ganglion neurons and plasticity of others following sciatic nerve section in adult and neonatal rats.
Topics: Aging; Animals; Cell Count; Cell Survival; Ganglia, Spinal; Horseradish Peroxidase; Immunohistochemistry; Neuronal Plasticity; Rats; Rats, Inbred Strains; Sciatic Nerve; Substance P; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; Wheat Germ Agglutinins | 1989 |
Endothelium-dependent and -independent responses to vasoactive substances of isolated human coronary arteries.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Aging; Bradykinin; Coronary Vessels; Cyclic GMP; Endothelium, Vascular; Female; Histamine; Humans; In Vitro Techniques; Infant; Male; Middle Aged; Serotonin; Substance P; Vasoconstrictor Agents; Vasodilator Agents | 1989 |
Effect of age and methacholine on the rate and coronary flow of isolated hearts of diabetic rats.
Topics: Aging; Animals; Atropine; Blood Glucose; Body Weight; Coronary Circulation; Diabetes Mellitus, Experimental; Heart; Heart Rate; In Vitro Techniques; Male; Methacholine Compounds; Organ Size; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Substance P; Time Factors | 1989 |
Substance P immunoreactivity in the superior cervical ganglia of normotensive and genetically hypertensive rats.
Topics: Aging; Animals; Capsaicin; Ganglia, Sympathetic; Hypertension; Neurons, Afferent; Neuropeptide Y; Rats; Rats, Inbred Strains; Substance P | 1989 |