suberoyl bis-hydroxamic acid has been researched along with Thyroid Carcinoma, Anaplastic in 1 studies
suberoyl bis-hydroxamic acid: antineoplastic, Histone Deacetylase inhibitor
Thyroid Carcinoma, Anaplastic: An aggressive THYROID GLAND malignancy which generally occurs in IODINE-deficient areas in people with previous thyroid pathology such as GOITER. It is associated with CELL DEDIFFERENTIATION of THYROID CARCINOMA (e.g., FOLLICULAR THYROID CARCINOMA; PAPILLARY THYROID CANCER). Typical initial presentation is a rapidly growing neck mass which upon metastasis is associated with DYSPHAGIA; NECK PAIN; bone pain; DYSPNEA; and NEUROLOGIC DEFICITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anaplastic thyroid cancer (ATC), usually derived from well-differentiated thyroid cancers is one of the most lethal human endocrine malignancies." | 1.46 | Suberoyl bis-hydroxamic acid activates Notch1 signaling and induces apoptosis in anaplastic thyroid carcinoma through p53. ( Gao, M; Li, J; Li, Y; Meng, X; Qian, B; Zhao, J; Zheng, X, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 2 |
| Zheng, X | 1 |
| Gao, M | 1 |
| Zhao, J | 1 |
| Li, Y | 1 |
| Meng, X | 1 |
| Qian, B | 1 |
1 other study available for suberoyl bis-hydroxamic acid and Thyroid Carcinoma, Anaplastic
| Article | Year |
|---|---|
Suberoyl bis-hydroxamic acid activates Notch1 signaling and induces apoptosis in anaplastic thyroid carcinoma through p53.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Dose-Resp | 2017 |