suberoyl bis-hydroxamic acid has been researched along with Kahler Disease in 2 studies
suberoyl bis-hydroxamic acid: antineoplastic, Histone Deacetylase inhibitor
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we demonstrate that Bim plays a functional role in bortezomib resistance in multiple myeloma (MM) cells and that targeting Bim by combining histone deacetylase inhibitors (HDACIs) with BH3 mimetics (eg, ABT-737) overcomes bortezomib resistance." | 3.80 | A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis. ( Chen, S; Dai, Y; Grant, S; Jones, R; Kmieciak, M; Leng, Y; Lin, H; Orlowski, RZ; Pei, XY; Zhang, Y; Zhou, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S | 2 |
| Zhang, Y | 1 |
| Zhou, L | 1 |
| Leng, Y | 1 |
| Lin, H | 1 |
| Kmieciak, M | 1 |
| Pei, XY | 2 |
| Jones, R | 1 |
| Orlowski, RZ | 1 |
| Dai, Y | 2 |
| Grant, S | 2 |
2 other studies available for suberoyl bis-hydroxamic acid and Kahler Disease
| Article | Year |
|---|---|
A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; A | 2014 |
Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; bcl-X Protein; Biphenyl Compounds; | 2009 |