styrene has been researched along with Lung Neoplasms in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 14 (46.67) | 24.3611 |
| 2020's | 4 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Brill, I; Delzell, E; Leader, M; Sathiakumar, N; Tipre, M | 1 |
| Andersen, ME; Bus, JS | 1 |
| Conolly, R; Hill, T | 1 |
| Bertke, SJ; Daniels, RD; Keil, AP | 1 |
| Arora, T; Bolaji, B; Brill, I; Chen, L; Delzell, E; Leader, M; Sathiakumar, N; Tipre, M | 1 |
| Andersen, ME; Banton, MI; Bus, JS; Cruzan, G; Dodd, D; Layko, DB; Raymond, J; Sarang, SS; Waites, R | 1 |
| Andersen, ME; Banton, MI; Bus, JS; Carlson, GP; Cruzan, G; Sarang, SS; Waites, R | 1 |
| Bertke, SJ; Daniels, RD; Yiin, JH | 1 |
| Andersen, ME; Banton, MI; Black, MB; Bus, JS; Cruzan, G; Dodd, DE; Layko, DB; McMullen, PD; Pendse, SN; Sarang, SS; Waites, R | 1 |
| Banton, MI; Bus, JS; Collins, JJ; Delzell, E; Gelbke, HP; Kester, JE; Moore, MM; Sarang, SS; Waites, R | 1 |
| Banton, M; Bus, J; Cruzan, G; Hotchkiss, J; Moore, C; Sarang, S; Sura, R; Yost, G | 1 |
| Cummings, KJ; Kreiss, K; McCague, AB | 1 |
| Bodner, KM; Bus, JS; Collins, JJ | 2 |
| Cruzan, G; Harkema, JR; Hosako, H; Murray, FJ; Wasil, JM | 1 |
| Bertke, SJ; Meyers, AR; Ruder, AM | 1 |
| Christensen, MS; Hansen, J; Kolstad, H; Ramlau-Hansen, CH; Toft, G | 1 |
| Carlson, GP | 1 |
| Carlson, GP; Harvilchuck, JA | 1 |
| Banton, M; Bus, J; Carlson, G; Cruzan, G; Gingell, R | 1 |
| Banton, M; Bus, J; Cruzan, G; Harkema, J; Hotchkiss, J; Sarang, S | 1 |
| Andrews, LS; Banton, MI; Bevan, C; Carlson, GP; Cruzan, G; Cushman, JR; Johnson, KA | 1 |
| Giardina, M; Olesik, SV | 1 |
| Boffetta, P; Brennan, P; Cassidy, A; Constantinescu, V; Csiki, I; Fabiánová, E; Fevotte, J; Fletcher, T; Foretova, L; Janout, V; Lissowska, J; Mannetje, A'; Rudnai, P; Scélo, G; Slamova, A; Szeszenia-Dabrowska, N; Zaridze, D | 1 |
| Huff, JE | 1 |
| Foster, JR; Green, T; Toghill, A | 1 |
| Anderson, D | 1 |
| Csanády, GA; Filser, JG; Kessler, W | 1 |
| Lutz, U; Lutz, WK; Otteneder, M | 1 |
| Brunnemann, KD; Cheng, SC; Hoffmann, D; Rivenson, A; Saa, V | 1 |
4 review(s) available for styrene and Lung Neoplasms
| Article | Year |
|---|---|
Evaluation of potential health effects associated with occupational and environmental exposure to styrene - an update.
Topics: Animals; Environmental Exposure; Humans; Inhalation Exposure; Lung Neoplasms; Mice; Occupational Exposure; Risk Assessment; Species Specificity; Styrene | 2019 |
Critical appraisal of the expression of cytochrome P450 enzymes in human lung and evaluation of the possibility that such expression provides evidence of potential styrene tumorigenicity in humans.
Topics: Carcinogens; Cytochrome P-450 Enzyme System; Humans; Inhalation Exposure; Lung; Lung Neoplasms; Microsomes; Styrene | 2008 |
Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: an endpoint/toxic response where data from multiple chemicals converge to support a mode of action.
Topics: Adenocarcinoma; Adenoma; Animals; Bronchioles; Carcinogens; Cell Proliferation; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Endpoint Determination; Enzyme Inhibitors; Epithelial Cells; Humans; Inhalation Exposure; Isoenzymes; Lung Neoplasms; Mice; Mice, Knockout; Mutagenicity Tests; Naphthalenes; Rats; Structure-Activity Relationship; Styrene | 2009 |
Styrene respiratory tract toxicity and mouse lung tumors are mediated by CYP2F-generated metabolites.
Topics: Animals; Cytochrome P-450 Enzyme System; Humans; Inhalation Exposure; Isoenzymes; Lung; Lung Neoplasms; Mice; Models, Biological; Nasal Mucosa; Rats; Respiratory System; Risk Assessment; Species Specificity; Styrene | 2002 |
26 other study(ies) available for styrene and Lung Neoplasms
| Article | Year |
|---|---|
Mortality Among Men and Women in the North American Synthetic Rubber Industry, 1943 to 2009.
Topics: Aged; Aged, 80 and over; Butadienes; Canada; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Manufacturing Industry; Middle Aged; Mortality; Neoplasms; Occupational Exposure; Proportional Hazards Models; Rubber; Styrene; Time Factors; United States; Urinary Bladder Neoplasms | 2019 |
Consideration of Styrene Transcriptomic Data Informs Mouse Lung Cyp2F2-Mediated Adverse Outcome Pathway.
Topics: Adverse Outcome Pathways; Animals; Cytochrome P-450 Enzyme System; Lung Neoplasms; Mice; Styrene; Transcriptome | 2020 |
Response to Consideration of Styrene Transcriptomic Data Informs Mouse Lung Cyp2F2-Mediated Adverse Outcome Pathway.
Topics: Adverse Outcome Pathways; Animals; Cytochrome P-450 Enzyme System; Lung Neoplasms; Mice; Styrene; Transcriptome | 2020 |
Lung Cancer Mortality and Styrene Exposure in the Reinforced-Plastics Boatbuilding Industry: Evaluation of Healthy Worker Survivor Bias.
Topics: Aged; Bias; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Manufacturing Industry; Middle Aged; Models, Statistical; Occupational Exposure; Plastics; Regression Analysis; Ships; Styrene; Survivors; Washington | 2021 |
1,3-Butadiene, styrene and selected outcomes among synthetic rubber polymer workers: Updated exposure-response analyses.
Topics: Aged; Butadienes; Canada; Carcinogens; Chemical Industry; Cohort Studies; Elastomers; Female; Humans; Lung Neoplasms; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Proportional Hazards Models; Pulmonary Disease, Chronic Obstructive; Sex Factors; Styrene; United States; Urinary Bladder Neoplasms | 2021 |
Editor's Highlight: Complete Attenuation of Mouse Lung Cell Proliferation and Tumorigenicity in CYP2F2 Knockout and CYP2F1 Humanized Mice Exposed to Inhaled Styrene for up to 2 Years Supports a Lack of Human Relevance.
Topics: Animals; Bronchioles; Carcinogens; Cytochrome P-450 Enzyme System; Humans; Inhalation Exposure; Lung; Lung Neoplasms; Male; Mice; Mice, Transgenic; Styrene | 2017 |
Based on an analysis of mode of action, styrene-induced mouse lung tumors are not a human cancer concern.
Topics: Animals; Carcinogens; Cell Survival; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Gene Expression; Humans; Lipid Metabolism; Lung; Lung Neoplasms; Male; Mice, Knockout; Rats; Risk Assessment; Species Specificity; Styrene | 2018 |
Cancer mortality update with an exposure response analysis among styrene-exposed workers in the reinforced plastics boatbuilding industry.
Topics: Aged; Cohort Studies; Employment; Female; Hematologic Neoplasms; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Manufacturing Industry; Middle Aged; Multiple Myeloma; Neoplasms; Occupational Exposure; Plastics; Proportional Hazards Models; Ships; Styrene; Time Factors; Washington | 2018 |
Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment.
Topics: Animals; Cell Proliferation; Cytochrome P-450 Enzyme System; Gene Expression Profiling; Humans; Inhalation Exposure; Lipid Metabolism; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Risk Assessment; Styrene; Time Factors | 2018 |
Studies of styrene, styrene oxide and 4-hydroxystyrene toxicity in CYP2F2 knockout and CYP2F1 humanized mice support lack of human relevance for mouse lung tumors.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Epoxy Compounds; Female; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Oxidoreductases, N-Demethylating; Phenols; Species Specificity; Styrene | 2013 |
Nonmalignant respiratory disease mortality in styrene-exposed workers.
Topics: Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Occupational Exposure; Pancreatic Neoplasms; Styrene | 2014 |
Nonmalignant respiratory disease mortality in styrene-exposed workers.
Topics: Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Occupational Exposure; Pancreatic Neoplasms; Styrene | 2014 |
Evaluation of the mode of action of mouse lung tumors induced by 4-methylimidazole.
Topics: Animals; Drug Evaluation, Preclinical; Female; Imidazoles; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Styrene | 2015 |
Mortality among styrene-exposed workers in the reinforced plastic boatbuilding industry.
Topics: Adult; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Manufacturing Industry; Neoplasms; Occupational Diseases; Occupational Exposure; Ovarian Neoplasms; Plastics; Pulmonary Disease, Chronic Obstructive; Ships; Smoking; Solvents; Styrene; Washington; Work; Young Adult | 2016 |
Cancer Incidence in Workers Exposed to Styrene in the Danish-reinforced Plastics Industry, 1968-2012.
Topics: Adult; Aged; Denmark; Employment; Female; Hodgkin Disease; Humans; Incidence; Industry; Leukemia, Myeloid; Lung Neoplasms; Male; Middle Aged; Neoplasms; Nose Neoplasms; Occupational Exposure; Paranasal Sinus Neoplasms; Plastics; Smoking; Styrene; Time Factors | 2017 |
Effect of multiple doses of styrene and R-styrene oxide on CC10, bax, and bcl-2 expression in isolated Clara cells of CD-1 mice.
Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Epithelial Cells; Epoxy Compounds; Lung; Lung Neoplasms; Male; Mice; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Styrene; Uteroglobin | 2009 |
CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced mouse lung tumors.
Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Epoxy Compounds; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Styrene | 2012 |
Cancer mortality of workers exposed to styrene in the U.S. Reinforced plastics and composite industry.
Topics: Cause of Death; Female; Follow-Up Studies; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Occupational Exposure; Pancreatic Neoplasms; Proportional Hazards Models; Risk; Styrene; United States | 2013 |
Application of low-temperature glassy carbon-coated macrofibers for solid-phase microextraction analysis of simulated breath volatiles.
Topics: Alkanes; Benzene Derivatives; Biomarkers; Breath Tests; Carbon; Gas Chromatography-Mass Spectrometry; Glass; Heptanes; Humans; Lung Neoplasms; Microchemistry; Reproducibility of Results; Sensitivity and Specificity; Styrene; Temperature; Volatilization | 2003 |
Occupational exposure to vinyl chloride, acrylonitrile and styrene and lung cancer risk (europe).
Topics: Acrylonitrile; Adult; Aged; Carcinogens; Case-Control Studies; Europe; Female; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Occupational Exposure; Odds Ratio; Risk Factors; Smoking; Styrene; Vinyl Chloride | 2004 |
Styrene, styrene oxide, polystyrene, and beta-nitrostyrene/styrene carcinogenicity in rodents.
Topics: Animals; Carcinogens; Chemical Industry; Epoxy Compounds; Ethers, Cyclic; Female; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Polystyrenes; Rats; Stomach Neoplasms; Styrene; Styrenes | 1984 |
The role of cytochromes P-450 in styrene induced pulmonary toxicity and carcinogenicity.
Topics: Administration, Inhalation; Animals; Carcinogens; Cell Division; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Female; Lung; Lung Diseases; Lung Neoplasms; Male; Mice; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Sex Characteristics; Styrene | 2001 |
Expression of ras (p21) protein in plasma from exposed workers and from patients with lung disease.
Topics: Adult; Aged; Antibodies, Monoclonal; Biomarkers; Blotting, Western; Butadienes; Carcinogens; Case-Control Studies; Female; Gene Expression Regulation; Humans; Luminescent Measurements; Lung Neoplasms; Male; Middle Aged; Occupational Exposure; Proto-Oncogene Mas; Pulmonary Disease, Chronic Obstructive; ras Proteins; Smoking; Styrene | 2001 |
Estimation of a possible tumorigenic risk of styrene from daily intake via food and ambient air.
Topics: Adult; Air Pollutants; Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Food Contamination; Humans; Lung Neoplasms; Male; Mice; Models, Biological; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Risk Assessment; Styrene | 2002 |
DNA adducts of styrene-7,8-oxide in target and non-target organs for tumor induction in rat and mouse after repeated inhalation exposure to styrene.
Topics: Administration, Inhalation; Animals; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Isomerism; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mutagens; Rats; Styrene | 2002 |
A study of tobacco carcinogenesis. XLVII. Bioassays of vinylpyridines for genotoxicity and for tumorigenicity in A/J mice.
Topics: Animals; Biotransformation; Carcinogens; DNA Repair; Female; Liver; Lung Neoplasms; Mice; Mice, Inbred A; Microsomes, Liver; Mutagenicity Tests; Mutagens; Nasal Mucosa; Nitrosamines; Pyridines; Rats; Salmonella typhimurium; Smoking; Styrene; Styrenes; Tobacco Smoke Pollution; Vinyl Compounds | 1992 |