strontium-radioisotopes and Pseudarthrosis

Topics: Autoradiography; Fractures, Bone; Humans; Kinetics; Polyphosphates; Pseudarthrosis; Radionuclide Imaging; Strontium Radioisotopes; Technetium; Technetium Compounds; Time Factors; Tin Polyphosphates; Wound Healing

In 40 patients with fracture of the femoral neck 85Sr scintimetry was performed at the time of nailing and 4 months postoperatively. The fractures were radiographed repeatedly for 5 years; thirteen fractures healed without complications, 22 developed necrosis of the femoral head, and 5 pseudarthrosis. The early isotope measurement did not distinguish between normal and necrosis cases even with detailed analysis. The 4 months activities were high in osteonecrosis and low pseudarthrosis. The latter observation is interpreted as evidence that non-union of a femoral neck fracture is due to severe permanent vascular damage.

Topics: Adult; Aged; Femoral Neck Fractures; Femur Head; Femur Head Necrosis; Humans; Middle Aged; Pseudarthrosis; Radiography; Scintillation Counting; Strontium Radioisotopes

Topics: Adolescent; Adult; Arthritis, Infectious; Bone Diseases; Bone Neoplasms; Bone Transplantation; Epiphyses, Slipped; Femoral Fractures; Femur Head; Follow-Up Studies; Fractures, Bone; Hip Joint; Humans; Joint Diseases; Osteochondritis; Osteomyelitis; Pseudarthrosis; Radionuclide Imaging; Strontium Radioisotopes; Transplantation, Homologous

The dynamics of uptake of osteotropic radionucleides in normal and abnormal bone were studied by means of sequential and functional scans. Various phosphate and phosphonate complexes were compared in vivo and in vitro. Only phosphonates were considered as suitable for bone scanning. In normal bones in beagles, radioactivity after HEDP fell to 65% after two hours, but was 105% with 18F. In relation to healing fractures, the curves differ quantitatively and qualitatively. In this situation, functional curves derived from dynamic scans provide a better parallel with histological findings than does static scintigraphy with an uptake quotient. Sequential and functional scanning are able to document the therapeutic effect of irradiation of bone metastases.

Topics: Animals; Bone and Bones; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Dogs; Female; Fluorine; Humans; Male; Neoplasm Metastasis; Phosphates; Prostatic Neoplasms; Pseudarthrosis; Radioisotopes; Radionuclide Imaging; Strontium; Strontium Radioisotopes; Technetium

Topics: Adolescent; Child; Female; Femoral Fractures; Fractures, Ununited; Humans; Male; Osteotomy; Pseudarthrosis; Radius; Strontium Radioisotopes; Traction; Ulna

Topics: Adolescent; Adult; Aged; Ankle Injuries; Female; Femoral Fractures; Femur Head Necrosis; Follow-Up Studies; Forearm Injuries; Fractures, Bone; Humans; Knee Injuries; Leg Injuries; Male; Middle Aged; Osteitis; Pseudarthrosis; Radionuclide Imaging; Strontium Radioisotopes; Technetium; Thrombophlebitis; Wound Healing

Topics: Atrophy; Bone Development; Humans; Pseudarthrosis; Radiography; Strontium Radioisotopes; Tibia; Tibial Fractures