strontium-radioisotopes and Plasmacytoma

strontium-radioisotopes has been researched along with Plasmacytoma* in 5 studies

Other Studies

5 other study(ies) available for strontium-radioisotopes and Plasmacytoma

ArticleYear
Oral Extramedullary Plasmacytoma Treatment Using a Combination of Marginal Excision and Strontium-90 Therapy in Five Dogs.
    Journal of veterinary dentistry, 2023, Volume: 40, Issue:2

    Extramedullary plasmacytoma (EMP) is a benign round cell tumor that is most commonly found in cutaneous locations in dogs and occurs less frequently in the oral cavity. They are highly radiosensitive, are distinct from systemic multiple myeloma syndrome and wide surgical excision is typically curative. This report describes five cases of non-invasive oral EMP in dogs treated with a combination of marginal excision and strontium-90 plesiotherapy. All five cases had narrow or incomplete margins on histopathologic evaluation but experienced no recurrence after combination therapy. Plesiotherapy radiation may offer a potential adjunct treatment for non-invasive oral EMP by providing a superficial dose of radiation that complements a less invasive surgical removal. The combination of plesiotherapy and marginal excision may offer an alternative to wide surgical excision for non-invasive oral EMPs.

    Topics: Animals; Dog Diseases; Dogs; Plasmacytoma; Strontium Radioisotopes

2023
Use of strontium-90 plesiotherapy for the treatment of a lingual plasmacytoma in a dog.
    The Journal of small animal practice, 2011, Volume: 52, Issue:4

    A 12-year-old, 25 kg, intact male St Bernard crossbreed was presented for treatment of a 538 mm ulcerated tumour on the dorsal tongue. Fine-needle aspiration cytology revealed a plasmacytoma. The dog staged negative for evidence of local metastatic or systemic disease. Histopathology confirmed the diagnosis. Treatment with one 150 Gy dose of radiation delivered with strontium-90 plesiotherapy was performed. Side effects were not noted and there was no visible evidence of tumour remaining at 2 months and 1 year after therapy.

    Topics: Animals; Dog Diseases; Dogs; Gamma Rays; Male; Plasmacytoma; Strontium Radioisotopes; Tongue Neoplasms; Treatment Outcome

2011
Mice treated with strontium 90: an animal model deficient in NK cells.
    British journal of cancer, 1981, Volume: 44, Issue:2

    Treatment of BALB/c mice with radioactive isotopes of the bone-seeking element strontium reduces the percentage of specific NK-cell cytotoxicity to only 2.6%, compared with 13.6% for normal BALB/c and 36.3% for athymic (nude) BALB/c. The syngeneic plasmacytoma NS-1 was used as target in a 4th in vitro NK-cell microassay. Marrow cellularity in treated mice is reduced to 12.5% of controls, but haemopoietic and stem-cell functions are taken over by the spleen and the peripheral blood picture remains relatively normal. Allogenic (H-2k) tumour transplants are rejected normally with good anti-H-2k alloantibody response. Haemopoietic and T- and B-cell functions are therefore substantially intact, and the defect seems confined to NK cells. In vivo, after s.c. inoculation of 10(6) NS-1 cells, 8/12 controls grew a solid tumour after a mean delay of 30.5 +/- 1.25 (s.e.) days, whereas 5/6 90Sr-treated mice grew the tumours after a delay of only 10.5 +/- 1.8 days. This markedly reduced delay in the 90Sr-treated mice lends support to suggestions that NK cells play an important role in resisting the establishment of tumour foci (i.e. in antitumour surveillance). Mice treated with 90Sr could be useful in evaluating the in vitro role of NK cells.

    Topics: Animals; Cell Line; Cell Survival; Female; Killer Cells, Natural; Lymphoma; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Strontium Radioisotopes; Time Factors; Transplantation, Homologous

1981
[The correlation of striontium test with clinical and roentgeno ogical finding in patients with plasmocytoma (author's transl)].
    Ceskoslovenska radiologie, 1976, Volume: 30, Issue:3

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Plasmacytoma; Radiography; Strontium Radioisotopes

1976
[Diagnosis, surgical and radiotherapeutic treatment of malignant tumors of the upper jaw].
    Strahlentherapie, 1974, Volume: 147, Issue:4

    Topics: Aged; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Child, Preschool; Diagnosis, Differential; Humans; Lymphatic Metastasis; Male; Maxillary Neoplasms; Plasmacytoma; Postoperative Care; Preoperative Care; Prognosis; Radioisotope Teletherapy; Radionuclide Imaging; Radiotherapy Dosage; Sarcoma; Strontium Radioisotopes

1974
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