strontium-radioisotopes and Glaucoma--Open-Angle

To evaluate the long-term outcome and complications of trabeculectomy with beta radiation.. Retrospective noncomparative case series.. Forty-three patients with confirmed primary open-angle glaucoma (POAG), who received trabeculectomy with adjunctive beta radiation at the Prince of Wales Hospital between June 1991 and November 1994.. Patients fulfilling the preceding criteria were followed up longitudinally. The visual acuity, intraocular pressure (IOP), bleb morphology, and complications were evaluated.. Visual acuity, IOP, bleb morphology, complications.. Forty-three eyes of 43 consecutive Chinese patients were recruited and successfully followed up for a minimum of 7 years. The mean age +/- 1 standard deviation (SD) was 60.9 +/- 13.0 years. There were 29 males and 14 females. The mean baseline IOP +/- 1 SD was 28.3 +/- 5.8 mmHg. The mean postoperative IOP +/- 1 SD after the initial trabeculectomy was 11.9 +/- 4.3 mmHg, and the mean number of preoperative IOP-lowering eyedrops +/- 1 SD was reduced from 2.8 +/- 0.5 to 0.7 +/- 1.0 at 7 years follow-up. The qualified success rate at 7 years follow-up, defined as IOP

Topics: Adult; Aged; Aged, 80 and over; Asian People; Beta Particles; Female; Follow-Up Studies; Glaucoma, Open-Angle; Hong Kong; Humans; Intraocular Pressure; Male; Middle Aged; Radiotherapy, Adjuvant; Retrospective Studies; Strontium Radioisotopes; Trabecular Meshwork; Trabeculectomy; Treatment Outcome; Visual Acuity; Visual Fields