strontium-radioisotopes and Choroid-Neoplasms

strontium-radioisotopes has been researched along with Choroid-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for strontium-radioisotopes and Choroid-Neoplasms

Article	Year
Results of treatment of choroidal malignant melanoma with high-dose-rate strontium-90 brachytherapy. A retrospective study of 46 patients treated between 1983 and 1995. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1998, Volume: 236, Issue:3 We review the results of treatment of small to medium-sized choroidal malignant melanomas after high-dose-rate brachytherapy with a strontium-90 applicator.. The applicator is positioned against the sclera using an afterloading technique. Brachytherapy is completed in a single session lasting 2-4 h with the patient under local anaesthesia. From September 1983 until March 1995, 46 eyes were treated in this way. Most tumours were 7-11 mm in diameter (range from 4.5-15 mm) with a mean height of approximately 3 mm (range from 1.5-7 mm). Follow-up ranged from 6 months to 12 years (mean 49 months).. Thirty of the 46 eyes had at the final evaluation a nonevolutive scar (20 of these after a single application, the others with some additional treatment). In 13 eyes the tumours were in involution but their complete destruction was not yet certain, and 3 eyes were enucleated for local recurrence. Three patients developed systemic metastases. No radiogenic complications were noticed.. Strontium-90 brachytherapy is a valuable and safe treatment technique for small to medium-sized choroidal malignant melanomas. In addition the use of a strontium-90 applicator is inexpensive thanks to this element's long half-life and the short application time. Topics: Adult; Aged; Aged, 80 and over; Brachytherapy; Choroid Neoplasms; Eye Enucleation; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Radiotherapy Dosage; Retrospective Studies; Strontium Radioisotopes; Survival Rate; Treatment Outcome	1998
Results of histo-pathologic examination of three enucleated eyes with a choroidal melanoma after strontium-90 irradiation. Bulletin de la Societe belge d'ophtalmologie, 1997, Volume: 265 Three patients with a choroidal melanoma, treated with HDR (High Dose Rate) Strontium-90 brachytherapy, underwent an enucleation. Radiation effect was only visible at the irradiation zone with a brisk transition to normal tissue. Tumour was replaced by necrotic and scar tissue. The underlying sclera had a markedly reduced number of fibrocytes, but no structural alteration of the collagen stroma. Topics: Aged; Brachytherapy; Cell Count; Choroid; Choroid Neoplasms; Cicatrix; Collagen; Eye Enucleation; Female; Fibroblasts; Follow-Up Studies; Humans; Male; Melanoma; Middle Aged; Necrosis; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Radiopharmaceuticals; Radiotherapy Dosage; Sclera; Strontium Radioisotopes	1997

Article

Year

Results of treatment of choroidal malignant melanoma with high-dose-rate strontium-90 brachytherapy. A retrospective study of 46 patients treated between 1983 and 1995.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1998, Volume: 236, Issue:3

We review the results of treatment of small to medium-sized choroidal malignant melanomas after high-dose-rate brachytherapy with a strontium-90 applicator.. The applicator is positioned against the sclera using an afterloading technique. Brachytherapy is completed in a single session lasting 2-4 h with the patient under local anaesthesia. From September 1983 until March 1995, 46 eyes were treated in this way. Most tumours were 7-11 mm in diameter (range from 4.5-15 mm) with a mean height of approximately 3 mm (range from 1.5-7 mm). Follow-up ranged from 6 months to 12 years (mean 49 months).. Thirty of the 46 eyes had at the final evaluation a nonevolutive scar (20 of these after a single application, the others with some additional treatment). In 13 eyes the tumours were in involution but their complete destruction was not yet certain, and 3 eyes were enucleated for local recurrence. Three patients developed systemic metastases. No radiogenic complications were noticed.. Strontium-90 brachytherapy is a valuable and safe treatment technique for small to medium-sized choroidal malignant melanomas. In addition the use of a strontium-90 applicator is inexpensive thanks to this element's long half-life and the short application time.

Topics: Adult; Aged; Aged, 80 and over; Brachytherapy; Choroid Neoplasms; Eye Enucleation; Female; Fluorescein Angiography; Follow-Up Studies; Fundus Oculi; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Radiotherapy Dosage; Retrospective Studies; Strontium Radioisotopes; Survival Rate; Treatment Outcome

1998

Results of histo-pathologic examination of three enucleated eyes with a choroidal melanoma after strontium-90 irradiation.

Bulletin de la Societe belge d'ophtalmologie, 1997, Volume: 265

Three patients with a choroidal melanoma, treated with HDR (High Dose Rate) Strontium-90 brachytherapy, underwent an enucleation. Radiation effect was only visible at the irradiation zone with a brisk transition to normal tissue. Tumour was replaced by necrotic and scar tissue. The underlying sclera had a markedly reduced number of fibrocytes, but no structural alteration of the collagen stroma.

Topics: Aged; Brachytherapy; Cell Count; Choroid; Choroid Neoplasms; Cicatrix; Collagen; Eye Enucleation; Female; Fibroblasts; Follow-Up Studies; Humans; Male; Melanoma; Middle Aged; Necrosis; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Radiopharmaceuticals; Radiotherapy Dosage; Sclera; Strontium Radioisotopes

1997