stiripentol has been researched along with Seizures in 35 studies
*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (5.71) | 18.2507 |
| 2000's | 3 (8.57) | 29.6817 |
| 2010's | 22 (62.86) | 24.3611 |
| 2020's | 8 (22.86) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel-Rehim, M; Aboul-Enein, MN; Amin, KM; Attia, MI; El-Azzouny, AA; El-Behairy, MF; Maklad, YA | 1 |
| Heulard, I; Reversat, L; Riban, V; Si Hocine, H; Verleye, M | 1 |
| Bragazzi, NL; Brigo, F; Igwe, SC | 4 |
| Aungaroon, G; Franz, DN; Horn, PS; Mehta, A | 1 |
| Vasquez, A; Wirrell, EC; Youssef, PE | 1 |
| Chancharme, L; Chemaly, N; Chiron, C; Nabbout, R | 1 |
| Frampton, JE | 1 |
| Caraballo, RH; Cross, JH; Guerrini, R; Lagae, L; Nabbout, R; Vigevano, F | 1 |
| Inoue, Y; Matsui, D; Ohtsuka, Y; Suzuki, K; Yamada, M | 1 |
| Buxton, L; Dahle, EJ; Handy, L; Johnson, KJ; Mensah, JA; Metcalf, CS; Pernici, CD; Smith, MD; West, PJ; Wilcox, KS | 1 |
| Fujioka, T; Kato, D; Madokoro, Y; Matsukawa, N; Mizuno, M; Terada, K; Toyoda, T; Uchida, Y | 1 |
| Aydınlı, N; Bektaş, G; Çalışkan, M; Ozkan, MU; Özmen, M; Tatlı, B; Uzunhan, TA; Yıldız, EP | 1 |
| Chiron, C | 2 |
| Eschbach, K; Knupp, KG | 1 |
| Chancharme, L; Chugani, H; de Menezes, MS; Devinsky, O; Franz, DN; Hamiwka, L; Hernandez, A; Laux, L; Le Guern, ME; Mikati, MA; Morse, RP; Saneto, RP; Sullivan, J; Valencia, I; Wirrell, EC | 1 |
| Baraban, SC; Dinday, MT; Hortopan, GA | 1 |
| Auvin, S; Desnous, B; Dournaud, P; Dupuis, N; Gressens, P; Lebon, S; Lecointe, C | 1 |
| Brigo, F; Storti, M | 1 |
| Benninger, F; Dressler, A; Feucht, M; Grassl, R; Gröppel, G; Mühlebner, A; Reiter-Fink, E; Reithofer, E; Trimmel-Schwahofer, P | 1 |
| Scharfman, HE | 1 |
| Inoue, T; Katsu, T; Lee, S; Otsuki, T; Sada, N | 1 |
| Brigo, F; Igwe, SC | 1 |
| Brigo, F; Igwe, SC; Storti, M | 1 |
| Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Trojnar, MK | 1 |
| Chemaly, N; Chipaux, M; Chiron, C; Copioli, C; Desguerre, I; Dulac, O; Nabbout, R | 1 |
| Auvin, S; Bellavoine, V; Delanoë, C; Mahfoufi, N; Merdariu, D | 1 |
| Cao, D; Inoue, Y; Ogiwara, I; Ohtani, H; Ohtani, S; Takahashi, Y; Yamakawa, K | 1 |
| Czuczwar, SJ; Luszczki, JJ | 1 |
| Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N | 1 |
| Arends, RH; Baillie, TA; Levy, RH; Shen, DD; Zhang, K | 1 |
| Boddy, AV; Lepage, F; Levy, RH; Savitch, JL; Shen, DD; Tombret, F | 1 |
13 review(s) available for stiripentol and Seizures
| Article | Year |
|---|---|
Stiripentol add-on therapy for drug-resistant focal epilepsy.
Topics: Anticonvulsants; Child; Dioxolanes; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Humans; Quality of Life; Randomized Controlled Trials as Topic; Seizures | 2022 |
Stiripentol for the treatment of seizures associated with Dravet syndrome in patients 6 months and older and taking clobazam.
Topics: Anticonvulsants; Child; Child, Preschool; Clobazam; Epilepsies, Myoclonic; Humans; Observational Studies as Topic; Randomized Controlled Trials as Topic; Seizures | 2023 |
Stiripentol: A Review in Dravet Syndrome.
Topics: Anticonvulsants; Dioxolanes; Epilepsies, Myoclonic; Humans; Seizures | 2019 |
Dravet syndrome: Treatment options and management of prolonged seizures.
Topics: Anticonvulsants; Diet, Ketogenic; Dioxolanes; Epilepsies, Myoclonic; Humans; Seizures; Valproic Acid | 2019 |
Stiripentol add-on therapy for drug-resistant focal epilepsy.
Topics: Anticonvulsants; Child; Dioxolanes; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Humans; Patient Dropouts; Randomized Controlled Trials as Topic; Seizures | 2020 |
Antiepileptic drugs for the treatment of infants with severe myoclonic epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dioxolanes; Epilepsies, Myoclonic; Female; Humans; Male; Patient Dropouts; Randomized Controlled Trials as Topic; Seizures | 2017 |
Stiripentol add-on therapy for focal refractory epilepsy.
Topics: Anticonvulsants; Child; Dioxolanes; Drug Therapy, Combination; Epilepsies, Partial; Humans; Randomized Controlled Trials as Topic; Seizures | 2018 |
Stiripentol for the treatment of seizures associated with Dravet syndrome.
Topics: Anticonvulsants; Dioxolanes; Epilepsies, Myoclonic; Humans; Seizures | 2019 |
Stiripentol for the treatment of seizures in Dravet syndrome.
Topics: Animals; Anticonvulsants; Child; Dioxolanes; Drug Approval; Epilepsies, Myoclonic; Humans; Seizures; Status Epilepticus | 2019 |
Antiepileptic drugs for the treatment of severe myoclonic epilepsy in infancy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dioxolanes; Epilepsies, Myoclonic; Female; Humans; Male; Randomized Controlled Trials as Topic; Seizures | 2013 |
Antiepileptic drugs for the treatment of infants with severe myoclonic epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dioxolanes; Epilepsies, Myoclonic; Female; Humans; Male; Randomized Controlled Trials as Topic; Seizures | 2015 |
Stiripentol for focal refractory epilepsy.
Topics: Anticonvulsants; Child; Dioxolanes; Drug Therapy, Combination; Epilepsies, Partial; Humans; Randomized Controlled Trials as Topic; Seizures | 2015 |
Stiripentol.
Topics: Anticonvulsants; Dioxolanes; Drug Interactions; Drugs, Investigational; Humans; Seizures | 2005 |
1 trial(s) available for stiripentol and Seizures
| Article | Year |
|---|---|
Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: a prospective pilot study.
Topics: Anticonvulsants; Child; Child, Preschool; Diet, Ketogenic; Dioxolanes; Epilepsies, Myoclonic; Female; Humans; Male; Pilot Projects; Prospective Studies; Seizures; Syndrome | 2011 |
21 other study(ies) available for stiripentol and Seizures
| Article | Year |
|---|---|
Design and synthesis of novel stiripentol analogues as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Dioxolanes; Drug Design; Hand Strength; Male; Mice; Seizures; Stereoisomerism; Toxicity Tests | 2012 |
Stiripentol inhibits spike-and-wave discharges in animal models of absence seizures: A new mechanism of action involving T-type calcium channels.
Topics: Animals; Anticonvulsants; Calcium Channels, T-Type; Dioxolanes; Disease Models, Animal; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Absence; Humans; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2022 |
Stiripentol for Drug-Resistant Epilepsy Treatment in Tuberous Sclerosis Complex.
Topics: Anticonvulsants; Drug Resistant Epilepsy; Humans; Seizures; Treatment Outcome; Tuberous Sclerosis | 2023 |
Initiating stiripentol before 2 years of age in patients with Dravet syndrome is safe and beneficial against status epilepticus.
Topics: Anticonvulsants; Child, Preschool; Epilepsies, Myoclonic; Female; Humans; Infant; Male; Retrospective Studies; Seizures; Status Epilepticus; Treatment Outcome | 2023 |
Long-term safety and effectiveness of stiripentol in patients with Dravet syndrome: Interim report of a post-marketing surveillance study in Japan.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dioxolanes; Epilepsies, Myoclonic; Epileptic Syndromes; Humans; Infant; Japan; Middle Aged; Pharmaceutical Preparations; Product Surveillance, Postmarketing; Seizures; Spasms, Infantile; Young Adult | 2021 |
Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program.
Topics: Animals; Anticonvulsants; Body Temperature; Dioxolanes; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Gene Knock-In Techniques; High-Throughput Screening Assays; Hyperthermia; Injections, Intraperitoneal; Male; Mice; National Institute of Neurological Disorders and Stroke (U.S.); NAV1.1 Voltage-Gated Sodium Channel; Seizures; United States | 2021 |
Stiripentol for the treatment of super-refractory status epilepticus with cross-sensitivity.
Topics: Adult; Aged; Anticonvulsants; Dioxolanes; Drug Eruptions; Female; Humans; Male; Middle Aged; Retrospective Studies; Seizures; Status Epilepticus; Young Adult | 2018 |
Efficacy of Stiripentol and the Clinical Outcome in Dravet Syndrome.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cognitive Dysfunction; Dioxolanes; Drug Resistant Epilepsy; Epilepsies, Myoclonic; Female; Humans; Male; Retrospective Studies; Seizures; Treatment Outcome | 2019 |
Stiripentol in Dravet syndrome: results of a retrospective U.S. study.
Topics: Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Dioxolanes; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Infant; Male; Retrospective Studies; Seizures; Treatment Outcome; United States; Valproic Acid | 2013 |
Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.
Topics: Animals; Anticonvulsants; Benzimidazoles; Bromides; Diazepam; Dioxolanes; Drug Evaluation, Preclinical; Epilepsies, Myoclonic; Gene Expression Profiling; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Potassium Compounds; Seizures; Valproic Acid; Voltage-Gated Sodium Channel beta-1 Subunit; Zebrafish; Zebrafish Proteins | 2013 |
Stiripentol exhibits higher anticonvulsant properties in the immature than in the mature rat brain.
Topics: Age Factors; Animals; Anticonvulsants; Brain; Brain Chemistry; Dioxolanes; Disease Models, Animal; Male; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, GABA-A; Seizures; Status Epilepticus | 2013 |
Efficacy and tolerability of the ketogenic diet in Dravet syndrome - Comparison with various standard antiepileptic drug regimen.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Bromides; Child; Child, Preschool; Clobazam; Diet, Ketogenic; Dioxolanes; Epilepsies, Myoclonic; Female; Fructose; Humans; Infant; Levetiracetam; Male; Piracetam; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Vagus Nerve Stimulation; Valproic Acid; Young Adult | 2015 |
Neuroscience. Metabolic control of epilepsy.
Topics: Animals; Anticonvulsants; Dioxolanes; Enzyme Inhibitors; L-Lactate Dehydrogenase; Safrole; Seizures | 2015 |
Epilepsy treatment. Targeting LDH enzymes with a stiripentol analog to treat epilepsy.
Topics: Animals; Anticonvulsants; Dioxolanes; Disease Models, Animal; Enzyme Inhibitors; L-Lactate Dehydrogenase; Membrane Potentials; Mice; Mice, Inbred ICR; Neurons; Patch-Clamp Techniques; Safrole; Seizures; Subthalamic Nucleus | 2015 |
Interactions of stiripentol with clobazam and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Analysis of Variance; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Benzodiazepines; Brain Chemistry; Clobazam; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Hand Strength; Male; Mice; Motor Activity; Seizures; Valproic Acid | 2010 |
Malignant migrating partial seizures of infancy controlled by stiripentol and clonazepam.
Topics: Anticonvulsants; Clonazepam; Dioxolanes; Electroencephalography; Epilepsies, Partial; Female; Head Movements; Humans; Infant; Magnetic Resonance Imaging; Seizures; Vomiting | 2013 |
Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.
Topics: Age Factors; Animals; Anticonvulsants; Benzodiazepines; Clobazam; Dioxolanes; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Genetic Predisposition to Disease; Hyperthermia, Induced; Mice; Mice, Transgenic; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Seizures; Sodium Channels | 2012 |
Biphasic characteristic of interactions between stiripentol and carbamazepine in the mouse maximal electroshock-induced seizure model: a three-dimensional isobolographic analysis.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Dioxolanes; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Male; Mice; Seizures | 2006 |
Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis.
Topics: Animals; Anticonvulsants; Brain Chemistry; Clonazepam; Dioxolanes; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Male; Mice; Neurotoxicity Syndromes; Pentylenetetrazole; Phenobarbital; Seizures; Valproic Acid | 2006 |
Stereoselective pharmacokinetics of stiripentol: an explanation for the development of tolerance to anticonvulsant effect.
Topics: Animals; Anticonvulsants; Brain; Chromatography, High Pressure Liquid; Dioxolanes; Drug Tolerance; Half-Life; In Vitro Techniques; Pentylenetetrazole; Rats; Seizures; Stereoisomerism | 1994 |
Comparative anticonvulsant potency and pharmacokinetics of (+)-and (-)-enantiomers of stiripentol.
Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Dioxolanes; Dose-Response Relationship, Drug; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism | 1992 |