stiripentol has been researched along with Disease Models, Animal in 11 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (9.09) | 18.2507 |
2000's | 2 (18.18) | 29.6817 |
2010's | 4 (36.36) | 24.3611 |
2020's | 4 (36.36) | 2.80 |
Authors | Studies |
---|---|
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Heulard, I; Reversat, L; Riban, V; Si Hocine, H; Verleye, M | 1 |
Attri, SV; Bhattacharyya, S; Das Radotra, B; Dhir, N; Jain, A; Mahendru, D; Malik, D; Medhi, B; Patial, A; Prakash, A; Sharma, AR; Sharma, S | 1 |
Fujiwara, A; Ito, S; Matsumura, S; Minami, T; Nakao, K; Ueno, T | 1 |
Auvin, S; Desnous, B; Dournaud, P; Dupuis, N; Gressens, P; Lebon, S; Lecointe, C | 1 |
Inoue, T; Katsu, T; Lee, S; Otsuki, T; Sada, N | 1 |
Cao, D; Inoue, Y; Ogiwara, I; Ohtani, H; Ohtani, S; Takahashi, Y; Yamakawa, K | 1 |
Grosenbaugh, DK; Mott, DD | 1 |
Ben-Ari, Y; Chiron, C; Gozlan, H; Quilichini, PP | 1 |
Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N | 1 |
Lockard, JS; Phillips, NK | 1 |
11 other study(ies) available for stiripentol and Disease Models, Animal
Article | Year |
---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Stiripentol inhibits spike-and-wave discharges in animal models of absence seizures: A new mechanism of action involving T-type calcium channels.
Topics: Animals; Anticonvulsants; Calcium Channels, T-Type; Dioxolanes; Disease Models, Animal; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Absence; Humans; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2022 |
Rat BM-MSCs secretome alone and in combination with stiripentol and ISRIB, ameliorated microglial activation and apoptosis in experimental stroke.
Topics: Animals; Apoptosis; Brain Ischemia; Cytokines; Disease Models, Animal; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Mesenchymal Stem Cells; Microglia; Rats; Rats, Wistar; Secretome; Stroke | 2023 |
Stiripentol alleviates neuropathic pain in L5 spinal nerve-transected mice.
Topics: Animals; Dioxolanes; Disease Models, Animal; Hyperalgesia; Mice; Neuralgia; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves | 2020 |
Stiripentol exhibits higher anticonvulsant properties in the immature than in the mature rat brain.
Topics: Age Factors; Animals; Anticonvulsants; Brain; Brain Chemistry; Dioxolanes; Disease Models, Animal; Male; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, GABA-A; Seizures; Status Epilepticus | 2013 |
Epilepsy treatment. Targeting LDH enzymes with a stiripentol analog to treat epilepsy.
Topics: Animals; Anticonvulsants; Dioxolanes; Disease Models, Animal; Enzyme Inhibitors; L-Lactate Dehydrogenase; Membrane Potentials; Mice; Mice, Inbred ICR; Neurons; Patch-Clamp Techniques; Safrole; Seizures; Subthalamic Nucleus | 2015 |
Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.
Topics: Age Factors; Animals; Anticonvulsants; Benzodiazepines; Clobazam; Dioxolanes; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Genetic Predisposition to Disease; Hyperthermia, Induced; Mice; Mice, Transgenic; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Seizures; Sodium Channels | 2012 |
Stiripentol is anticonvulsant by potentiating GABAergic transmission in a model of benzodiazepine-refractory status epilepticus.
Topics: Animals; Anticonvulsants; Benzodiazepines; Dioxolanes; Disease Models, Animal; Drug Synergism; Inhibitory Postsynaptic Potentials; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Synaptic Transmission | 2013 |
Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels.
Topics: Animals; Animals, Newborn; Anticonvulsants; Chloride Channels; Dioxolanes; Disease Models, Animal; Drug Interactions; Epilepsy; Excitatory Postsynaptic Potentials; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Neural Inhibition; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Pentobarbital; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission | 2006 |
Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis.
Topics: Animals; Anticonvulsants; Brain Chemistry; Clonazepam; Dioxolanes; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Male; Mice; Neurotoxicity Syndromes; Pentylenetetrazole; Phenobarbital; Seizures; Valproic Acid | 2006 |
Infant monkey hyperexcitability after prenatal exposure to antiepileptic compounds.
Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Carbamazepine; Dioxolanes; Disease Models, Animal; Female; Humans; Hyperkinesis; Macaca fascicularis; Male; Maternal-Fetal Exchange; Memory; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects | 1996 |