stilbenes and Vaginitis

stilbenes has been researched along with Vaginitis* in 6 studies

Other Studies

6 other study(ies) available for stilbenes and Vaginitis

ArticleYear
Resveratrol-loaded liposomes for topical treatment of the vaginal inflammation and infections.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Nov-15, Volume: 79

    Resveratrol (RES), chemically known as 3,5,4'-trihydroxy-trans-stilbene, is a promising multi-targeted anti-oxidative and anti-inflammatory natural polyphenol. Preclinical studies showed its biological activities against the pathogens of sexually transmitted diseases causing vaginal inflammation and infections. Due to its low solubility and poor bioavailability, the optimal therapeutic uses are limited. Therefore, a clinically acceptable topical vaginal formulation of RES exhibiting optimal therapeutic effects is highly desirable. For this purpose, we prepared and optimized chitosan-coated liposomes with RES. The coated vesicles (mean diameter 200nm) entrapped up to 77% of RES, a sufficient load to assure required therapeutic outcome. In vitro drug release study showed the ability of liposomes to provide sustained release of RES. In vitro anti-oxidative activities of RES, namely DPPH and ABTS(•+) radicals scavenging assays, confirmed RES to be as potent as standard anti-oxidants, vitamins C and E. The anti-oxidative activities of RES and its corresponding liposomal formulation were also compared by measuring enhanced superoxide dismutase (SOD) activities in lipopolysaccharide (LPS)-induced J774A.1 cells. In vitro anti-inflammatory activities were compared by measuring nitric oxide (NO), tumor necrosis factor (TNF)-α and interleukin (IL)-1β production in LPS-induced J774A.1 cells. Liposomal RES was found to exhibit stronger anti-oxidative and anti-inflammatory activities than RES solution.

    Topics: Administration, Intravaginal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Female; Interleukin-1beta; Liposomes; Mice; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Vaginitis; Vaginosis, Bacterial

2015
[A new therapy of bacterial & trichomonal leukorrheas].
    Therapie der Gegenwart, 1959, Volume: 98, Issue:6

    Topics: Female; Humans; Leukorrhea; Stilbenes; Sulfonamides; Trichomonas; Trichomonas Infections; Trichomonas Vaginitis; Vaginitis; Vulvovaginitis

1959
[Therapy of nonspecific colpitis in medical practice].
    Die Medizinische, 1958, Dec-06, Volume: 32, Issue:49

    Topics: Carbohydrates; Female; Humans; Lactic Acid; Stilbenes; Vaginitis; Vaginosis, Bacterial; Vulvovaginitis

1958
[Therapeutic use of colpan vaginal capsules].
    Munchener medizinische Wochenschrift (1950), 1958, Nov-14, Volume: 100, Issue:46

    Topics: Capsules; Carbohydrates; Female; Hexoses; Humans; Stilbenes; Vaginitis; Vulvovaginitis

1958
[Cytological and histological studies in the stilbene therapy of senile vaginitis].
    Medizinische Klinik, 1953, Jun-19, Volume: 48, Issue:25

    Topics: Aged; Female; Humans; Stilbenes; Vaginitis

1953
Therapy of vetular colpitis with follicle hormone and stilbene crystal suspensions.
    Wiener klinische Wochenschrift, 1948, Sep-17, Volume: 60, Issue:37

    Topics: Female; Follicle Stimulating Hormone; Hormones; Humans; Obesity; Stilbenes; Vagina; Vaginitis

1948