steviol has been researched along with Ovarian-Neoplasms* in 1 studies
1 other study(ies) available for steviol and Ovarian-Neoplasms
Article | Year |
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Stereoselective Synthesis and Antiproliferative Activities of Tetrafunctional Diterpene Steviol Derivatives.
A new family of diterpene-type aminotriol derivatives has been synthesised from stevioside in a stereoselective manner. The key intermediate spiro-epoxide was prepared through the methyl ester of the allilyc diol derived from steviol. The oxirane ring was opened with primary and secondary amines, providing a versatile library of aminotriols. The corresponding primary aminotriol was formed by palladium-catalysed hydrogenation, and an Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Molecular Structure; Ovarian Neoplasms; Structure-Activity Relationship | 2023 |