sterofundin and Cholelithiasis

The dynamics of microbial endotoxemia in group of 149 patients with cholelithiasis complicated by obstructive jaundice has been studied as dependent on the perioperative tactics of infusion therapy. The perioperative period in obstructive jaundice patients is complicated by a significant increase in lipopolysaccharidemia caused by translocation mechanisms and disorders of the liver detoxification function. In Group 1, 47 patients received infusion therapy including Ringer's solution and 10% glucose solution at a 1:1 ratio. In group 2, 55 patients received infusion therapy with only Sterofundin G-5 solution. In Group 3, 47 patients received the infusion therapy with remaxol in a dose of 800 ml/day. It is established that the infusion of Sterofundin G-5, and to a greater extent the infusion of remaxol, reduces the early postoperative degree of decompensation and accelerates recovery of the detoxifying function of Kupffer cells with respect to microbial endotoxin.

Topics: Cholelithiasis; Endotoxemia; Fluid Therapy; Glucose; Gram-Negative Bacterial Infections; Humans; Infusions, Parenteral; Isotonic Solutions; Jaundice, Obstructive; Kupffer Cells; Lipopolysaccharides; Liver; Organic Chemicals; Ringer's Solution; Succinates