stepholidine and Dyskinesia--Drug-Induced

stepholidine has been researched along with Dyskinesia--Drug-Induced* in 2 studies

Trials

2 trial(s) available for stepholidine and Dyskinesia--Drug-Induced

ArticleYear
[Clinical study on the treatment of dyskinesia by L-stepholidine].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1989, Volume: 22, Issue:6

    134 cases of dyskinesia caused by various CNS diseases were treated with a new type of DA blocker L-Stepholidine (1-SPD). Good response was obtained in 72% (29/40) of L-dopa induced abnormal involuntary movements in Parkinson disease, 79% (34/43) of Tourette syndrome, and 65% (15/23) of tardive dyskinesia through a short-term follow-up. No serious side effects were found within the therapeutic dosage of 50-225mg/day The results showed that L-SPD is a new type of anti-dyskinesia agent deserving further pharmacological investigation.

    Topics: Aged; Berberine; Berberine Alkaloids; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Movement Disorders; Multicenter Studies as Topic; Tourette Syndrome

1989
[A controlled study on the treatment of tardive dyskinesia using 1-stepholidine].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1988, Volume: 21, Issue:5

    Topics: Adult; Aged; Berberine; Berberine Alkaloids; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Stereoisomerism

1988