stemphone has been researched along with Atherosclerosis* in 1 studies
1 other study(ies) available for stemphone and Atherosclerosis
| Article | Year |
|---|---|
Inhibition of lipid droplet accumulation in mouse macrophages by stemphone derivatives.
From a study on the biological activity of fungal stemphones and their derivatives, five derivatives having an O-alkyl moiety at C-11 of stemphone C were found to inhibit lipid droplet accumulation in macrophages without any cytotoxic effect. Among the derivatives, those having O-isopropyl and O-isobutyl were the most potent inhibitors by blocking the synthesis of both cholesteryl ester (CE) and triacylglycerol (TG), the main constituents of lipid droplets in macrophages. Topics: Animals; Atherosclerosis; Benzoquinones; Cholesterol; Cholesterol Esters; Diacylglycerol O-Acyltransferase; Foam Cells; Lipid Metabolism; Macrophages, Peritoneal; Mice; Sterol O-Acyltransferase; Triglycerides | 2008 |