stearic acid has been researched along with Multiple Sclerosis in 3 studies
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The stearic acid-based SLNs were below 100 nm with almost neutral zeta potential and offered higher drug entrapment and drug loading." | 1.51 | Oral Delivery of Methylthioadenosine to the Brain Employing Solid Lipid Nanoparticles: Pharmacokinetic, Behavioral, and Histopathological Evidences. ( Gupta, V; Katare, OP; Kaur, R; Kaushal, N; Kumar, A; Kumar, P; Malik, R; Raza, K; Sharma, G; Thakur, K, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, P | 1 |
| Sharma, G | 1 |
| Gupta, V | 1 |
| Kaur, R | 1 |
| Thakur, K | 1 |
| Malik, R | 1 |
| Kumar, A | 1 |
| Kaushal, N | 1 |
| Katare, OP | 1 |
| Raza, K | 1 |
| BAKER, RW | 1 |
| THOMPSON, RH | 1 |
| ZILKHA, KJ | 1 |
| Sargent, JR | 1 |
| Coupland, K | 1 |
| Wilson, R | 1 |
3 other studies available for stearic acid and Multiple Sclerosis
| Article | Year |
|---|---|
Oral Delivery of Methylthioadenosine to the Brain Employing Solid Lipid Nanoparticles: Pharmacokinetic, Behavioral, and Histopathological Evidences.
Topics: Administration, Oral; Animals; Biological Availability; Brain; Deoxyadenosines; Drug Delivery System | 2019 |
Fatty-acid composition of brain lecithins in multiple sclerosis.
Topics: Brain; Fatty Acids; Fatty Acids, Essential; Lecithins; Multiple Sclerosis; Oleic Acid; Oleic Acids; | 1963 |
Nervonic acid and demyelinating disease.
Topics: Adrenoleukodystrophy; Fatty Acids, Monounsaturated; Fibroblasts; Humans; Multiple Sclerosis; Myelin | 1994 |