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stearic acid and Leukodystrophy, Metachromatic

stearic acid has been researched along with Leukodystrophy, Metachromatic in 3 studies

octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.

Leukodystrophy, Metachromatic: An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.

Research Excerpts

ExcerptRelevanceReference
"Metachromatic leukodystrophy is the name given to a group of diseases in patients having a deficiency of CS sulfatase activity."1.26Metabolism of fatty acid-labeled cerebroside sulfate in cultured cells from controls and metachromatic leukodystrophy patients. Use in the prenatal identification of a false positive fetus. ( Bitter, MA; Kudoh, T; Malmstrom, J; Sattler, M; Wenger, DA, 1981)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Isaac, G1
Pernber, Z1
Gieselmann, V1
Hansson, E1
Bergquist, J1
MÃ¥nsson, JE1
Kudoh, T1
Sattler, M1
Malmstrom, J1
Bitter, MA1
Wenger, DA2
Rafi, MA1
Amini, S1
Zhang, XL1

Other Studies

3 other studies available for stearic acid and Leukodystrophy, Metachromatic

ArticleYear
Sulfatide with short fatty acid dominates in astrocytes and neurons.
    The FEBS journal, 2006, Volume: 273, Issue:8

    Topics: Animals; Astrocytes; Cells, Cultured; Cerebroside-Sulfatase; Fatty Acids; Female; Leukodystrophy, Me

2006
Metabolism of fatty acid-labeled cerebroside sulfate in cultured cells from controls and metachromatic leukodystrophy patients. Use in the prenatal identification of a false positive fetus.
    The Journal of laboratory and clinical medicine, 1981, Volume: 98, Issue:5

    Topics: Amniotic Fluid; Brain; Cells, Cultured; Cerebroside-Sulfatase; Cerebrosides; Chromatography, Thin La

1981
Correction of sulfatide metabolism after transfer of prosaposin cDNA to cultured cells from a patient with SAP-1 deficiency.
    American journal of human genetics, 1992, Volume: 50, Issue:6

    Topics: Antisense Elements (Genetics); Base Sequence; Cells, Cultured; Cerebroside-Sulfatase; Child; Fibrobl

1992