stearic acid has been researched along with Leukodystrophy, Metachromatic in 3 studies
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
Leukodystrophy, Metachromatic: An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metachromatic leukodystrophy is the name given to a group of diseases in patients having a deficiency of CS sulfatase activity." | 1.26 | Metabolism of fatty acid-labeled cerebroside sulfate in cultured cells from controls and metachromatic leukodystrophy patients. Use in the prenatal identification of a false positive fetus. ( Bitter, MA; Kudoh, T; Malmstrom, J; Sattler, M; Wenger, DA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Isaac, G | 1 |
| Pernber, Z | 1 |
| Gieselmann, V | 1 |
| Hansson, E | 1 |
| Bergquist, J | 1 |
| Månsson, JE | 1 |
| Kudoh, T | 1 |
| Sattler, M | 1 |
| Malmstrom, J | 1 |
| Bitter, MA | 1 |
| Wenger, DA | 2 |
| Rafi, MA | 1 |
| Amini, S | 1 |
| Zhang, XL | 1 |
3 other studies available for stearic acid and Leukodystrophy, Metachromatic
| Article | Year |
|---|---|
Sulfatide with short fatty acid dominates in astrocytes and neurons.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebroside-Sulfatase; Fatty Acids; Female; Leukodystrophy, Me | 2006 |
Metabolism of fatty acid-labeled cerebroside sulfate in cultured cells from controls and metachromatic leukodystrophy patients. Use in the prenatal identification of a false positive fetus.
Topics: Amniotic Fluid; Brain; Cells, Cultured; Cerebroside-Sulfatase; Cerebrosides; Chromatography, Thin La | 1981 |
Correction of sulfatide metabolism after transfer of prosaposin cDNA to cultured cells from a patient with SAP-1 deficiency.
Topics: Antisense Elements (Genetics); Base Sequence; Cells, Cultured; Cerebroside-Sulfatase; Child; Fibrobl | 1992 |