stearic acid has been researched along with Leukemia in 2 studies
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cytarabine (Cyt) used in the treatment of meningeal leukemia is associated with drawbacks like non selectivity to tumor cells, very short half-life and inability to cross blood brain barrier (BBB) due to its hydrophilic nature." | 7.78 | Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies. ( Dube, B; Sawant, K; Sharma, P, 2012) |
| "Cytarabine (Cyt) used in the treatment of meningeal leukemia is associated with drawbacks like non selectivity to tumor cells, very short half-life and inability to cross blood brain barrier (BBB) due to its hydrophilic nature." | 3.78 | Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies. ( Dube, B; Sawant, K; Sharma, P, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Håversen, L | 1 |
| Danielsson, KN | 1 |
| Fogelstrand, L | 1 |
| Wiklund, O | 1 |
| Sharma, P | 1 |
| Dube, B | 1 |
| Sawant, K | 1 |
2 other studies available for stearic acid and Leukemia
| Article | Year |
|---|---|
Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages.
Topics: Cell Line, Tumor; Ceramides; Cytokines; Fatty Acids; Humans; Interleukin-1beta; Interleukin-8; JNK M | 2009 |
Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Delayed-Action Preparations; Drug Carr | 2012 |