Page last updated: 2024-11-04

stearic acid and Insulin Resistance

stearic acid has been researched along with Insulin Resistance in 11 studies

octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"We found strong positive relationships between adipose tissue TG content of the fatty acids myristic acid (14:0) and stearic acid (18:0) with insulin sensitivity (HOMA model) (p < 0."3.75Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans. ( Dennis, AL; Frayn, KN; Harnden, KE; Hodson, L; Humphreys, SM; Micklem, KJ; Neville, MJ; Roberts, R, 2009)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's7 (63.64)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Wang, L1
Xu, F1
Song, Z1
Han, D1
Zhang, J1
Chen, L1
Na, L3
Hilvo, M1
Salonurmi, T1
Havulinna, AS1
Kauhanen, D1
Pedersen, ER1
Tell, GS1
Meyer, K1
Teeriniemi, AM1
Laatikainen, T1
Jousilahti, P1
Savolainen, MJ1
Nygård, O1
Salomaa, V1
Laaksonen, R1
Ng, YT1
Voon, PT1
Ng, TKW1
Lee, VKM1
Mat Sahri, M1
Mohd Esa, N1
Ong, SH1
Ong, ASH1
Liu, L2
Chu, X2
Yuan, F1
Li, Y2
Sun, C2
Roberts, R1
Hodson, L1
Dennis, AL1
Neville, MJ1
Humphreys, SM1
Harnden, KE1
Micklem, KJ1
Frayn, KN1
Hirabara, SM1
Curi, R1
Maechler, P1
Watanabe, Y1
Nakamura, T1
Ishikawa, S1
Fujisaka, S1
Usui, I1
Tsuneyama, K1
Ichihara, Y1
Wada, T1
Hirata, Y1
Suganami, T1
Izaki, H1
Akira, S1
Miyake, K1
Kanayama, HO1
Shimabukuro, M1
Sata, M1
Sasaoka, T1
Ogawa, Y1
Tobe, K1
Takatsu, K1
Nagai, Y1
Lu, H1
Li, S1
Kurotani, K1
Sato, M1
Ejima, Y1
Nanri, A1
Yi, S1
Pham, NM1
Akter, S1
Poudel-Tandukar, K1
Kimura, Y1
Imaizumi, K1
Mizoue, T1
Weigert, C1
Klopfer, K1
Kausch, C1
Brodbeck, K1
Stumvoll, M1
Häring, HU1
Schleicher, ED1
Song, MJ1
Kim, KH1
Yoon, JM1
Kim, JB1

Trials

2 trials available for stearic acid and Insulin Resistance

ArticleYear
Interesterified Palm Olein (IEPalm) and Interesterified Stearic Acid-Rich Fat Blend (IEStear) Have No Adverse Effects on Insulin Resistance: A Randomized Control Trial.
    Nutrients, 2018, Aug-17, Volume: 10, Issue:8

    Topics: Adiposity; Adult; Apolipoprotein A-I; Apolipoprotein B-100; Blood Glucose; Body Mass Index; Choleste

2018
Decreasing high postprandial stearic acid in impaired fasting glucose by dietary regulation.
    European journal of clinical nutrition, 2016, Volume: 70, Issue:7

    Topics: Adiponectin; Adult; Aged; Blood Glucose; Dietary Carbohydrates; Fasting; Fatty Acids, Nonesterified;

2016

Other Studies

9 other studies available for stearic acid and Insulin Resistance

ArticleYear
A high fat diet with a high C18:0/C16:0 ratio induced worse metabolic and transcriptomic profiles in C57BL/6 mice.
    Lipids in health and disease, 2020, Jul-21, Volume: 19, Issue:1

    Topics: Animals; Body Weight; Diet, High-Fat; Fatty Acids; Insulin Resistance; Interleukin-6; Lipid Metaboli

2020
Ceramide stearic to palmitic acid ratio predicts incident diabetes.
    Diabetologia, 2018, Volume: 61, Issue:6

    Topics: Aged; Angina Pectoris; Body Mass Index; Ceramides; Cohort Studies; Coronary Angiography; Diabetes Me

2018
Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans.
    Diabetologia, 2009, Volume: 52, Issue:5

    Topics: Adipocytes; Adipose Tissue; Biopsy; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies;

2009
Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells.
    Journal of cellular physiology, 2010, Volume: 222, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Fatty Acids; Glucose; Insulin; Insu

2010
The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation.
    Diabetes, 2012, Volume: 61, Issue:5

    Topics: Adipocytes; Adipose Tissue; Animals; Antigens, CD; Antigens, Surface; Coculture Techniques; Dietary

2012
Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemia.
    Diabetes, 2013, Volume: 62, Issue:2

    Topics: Acetyl-CoA Carboxylase; Acetyltransferases; Animals; Fatty Acid Elongases; Fatty Acid Synthases; Fem

2013
High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance.
    Nutrition research (New York, N.Y.), 2012, Volume: 32, Issue:9

    Topics: 8,11,14-Eicosatrienoic Acid; Adult; Aged; Asian People; C-Peptide; Cholesterol Esters; Chromatograph

2012
Palmitate-induced activation of the hexosamine pathway in human myotubes: increased expression of glutamine:fructose-6-phosphate aminotransferase.
    Diabetes, 2003, Volume: 52, Issue:3

    Topics: Cells, Cultured; DNA; Fatty Acids, Unsaturated; Gene Expression; Glucose; Glutamine-Fructose-6-Phosp

2003
Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes.
    Biochemical and biophysical research communications, 2006, Aug-04, Volume: 346, Issue:3

    Topics: Adipocytes; Animals; Cell Differentiation; Cell Line; Gene Expression Regulation; Glucose; Insulin;

2006