stearic acid has been researched along with Hyperlipidemias in 11 studies
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
Hyperlipidemias: Conditions with excess LIPIDS in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the effects on postprandial lipemia and glycemia are less clear." | 7.01 | Effects of two consecutive mixed meals high in palmitic acid or stearic acid on 8-h postprandial lipemia and glycemia in healthy-weight and overweight men and postmenopausal women: a randomized controlled trial. ( Blom, WAM; Mensink, RP; Plat, J; van Rooijen, MA; Zock, PL, 2021) |
| "The aim of this study was to study the effect of adding polyunsaturated fatty acid (PUFA) n-3 or placebo (containing oleic acid) to a combined statin-fibrate treatment on plasma lipoproteins, lipoperoxidation, glucose homeostasis, total homocysteine (tHcy) and microalbuminuria (MA) in patients with diabetic dyslipidemia (DDL)." | 5.12 | N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination. ( Písaríková, A; Stanková, B; Tvrzická, E; Vecka, M; Zák, A; Zeman, M, 2006) |
| "However, the effects on postprandial lipemia and glycemia are less clear." | 3.01 | Effects of two consecutive mixed meals high in palmitic acid or stearic acid on 8-h postprandial lipemia and glycemia in healthy-weight and overweight men and postmenopausal women: a randomized controlled trial. ( Blom, WAM; Mensink, RP; Plat, J; van Rooijen, MA; Zock, PL, 2021) |
| "The intent of this investigation was to improve pharmacokinetic (PK) and pharmacodynamic (PD) effects of Rosuvastatin calcium (RC) by solid lipid nanoparticles (SLNs)." | 1.46 | Improved anti-hyperlipidemic activity of Rosuvastatin Calcium via lipid nanoparticles: Pharmacokinetic and pharmacodynamic evaluation. ( Dudhipala, N; Veerabrahma, K, 2017) |
| " This study aimed to examine the adverse effects of stearic acid on beta cells and the potential mechanisms through which these are mediated." | 1.43 | Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway. ( Chen, Y; Chu, X; Cui, H; Hao, L; Li, S; Lin, S; Lu, H; Lv, L; Na, L; Sun, C; Zi, T, 2016) |
| "Fenofibrate lipospheres were prepared by the melt dispersion technique." | 1.39 | Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. ( Lakshmi, PK; Saroja, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| van Rooijen, MA | 1 |
| Plat, J | 1 |
| Zock, PL | 1 |
| Blom, WAM | 1 |
| Mensink, RP | 1 |
| Alfieri, A | 1 |
| Imperlini, E | 1 |
| Nigro, E | 1 |
| Vitucci, D | 1 |
| Orrù, S | 1 |
| Daniele, A | 1 |
| Buono, P | 1 |
| Mancini, A | 1 |
| Saroja, C | 1 |
| Lakshmi, PK | 1 |
| Park, KH | 1 |
| Kim, JM | 1 |
| Cho, KH | 1 |
| Lu, H | 2 |
| Hao, L | 1 |
| Li, S | 2 |
| Lin, S | 1 |
| Lv, L | 1 |
| Chen, Y | 1 |
| Cui, H | 1 |
| Zi, T | 1 |
| Chu, X | 2 |
| Na, L | 2 |
| Sun, C | 2 |
| Dudhipala, N | 1 |
| Veerabrahma, K | 1 |
| Berry, SE | 1 |
| Karupaiah, T | 1 |
| Tan, CH | 1 |
| Chinna, K | 1 |
| Sundram, K | 1 |
| Liu, L | 1 |
| Li, Y | 1 |
| Zeman, M | 1 |
| Zák, A | 1 |
| Vecka, M | 1 |
| Tvrzická, E | 1 |
| Písaríková, A | 1 |
| Stanková, B | 1 |
| Titov, VN | 1 |
| Arapbaeva, AA | 1 |
| Kukharchuk, VV | 1 |
| Balakina, MV | 1 |
| Tishinin, MA | 1 |
| Ameliushkina, VA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of C16:0 Versus C18:0 on HDL Metabolism and Other Cardiometabolic Risk Markers: A Dietary Intervention Study in Healthy Normal-weight and Overweight Subjects[NCT02835651] | 41 participants (Actual) | Interventional | 2016-04-14 | Completed | |||
| Comparison of the Effect of Medium-Chain Fatty Acids and Long-Chain Fatty Acids on Postprandial Appetite and Lipemia[NCT05539742] | 26 participants (Actual) | Interventional | 2022-06-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for stearic acid and Hyperlipidemias
| Article | Year |
|---|---|
Effects of Plant Oil Interesterified Triacylglycerols on Lipemia and Human Health.
Topics: Dietary Fats; Fatty Acids; Humans; Hyperlipidemias; Palmitic Acid; Plant Oils; Stearic Acids; Stereo | 2017 |
Triacylglycerol structure and interesterification of palmitic and stearic acid-rich fats: an overview and implications for cardiovascular disease.
Topics: Adult; Animals; Coronary Disease; Diet, Atherogenic; Dietary Fats; Esterification; Humans; Hyperlipi | 2009 |
3 trials available for stearic acid and Hyperlipidemias
| Article | Year |
|---|---|
Effects of two consecutive mixed meals high in palmitic acid or stearic acid on 8-h postprandial lipemia and glycemia in healthy-weight and overweight men and postmenopausal women: a randomized controlled trial.
Topics: Blood Glucose; Cross-Over Studies; Dietary Fats; Female; Humans; Hyperlipidemias; Male; Meals; Overw | 2021 |
The chain length of dietary saturated fatty acids affects human postprandial lipemia.
Topics: Adult; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Coconut Oil; Corn Oil; Cross-Ove | 2011 |
N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination.
Topics: Adult; Albuminuria; Cholesterol Esters; Clofibric Acid; Diabetes Mellitus, Type 1; Dietary Supplemen | 2006 |
6 other studies available for stearic acid and Hyperlipidemias
| Article | Year |
|---|---|
Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design.
Topics: Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Fatty Alcohols; Feno | 2013 |
Elaidic acid (EA) generates dysfunctional high-density lipoproteins and consumption of EA exacerbates hyperlipidemia and fatty liver change in zebrafish.
Topics: Animals; Antioxidants; Apolipoprotein A-I; Atherosclerosis; Cells, Cultured; Cholesterol Ester Trans | 2014 |
Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway.
Topics: Animals; Cell Line; eIF-2 Kinase; Hyperlipidemias; Insulin; Insulin-Secreting Cells; Mice; Mice, Inb | 2016 |
Improved anti-hyperlipidemic activity of Rosuvastatin Calcium via lipid nanoparticles: Pharmacokinetic and pharmacodynamic evaluation.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Chromatography, High Press | 2017 |
Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemia.
Topics: Acetyl-CoA Carboxylase; Acetyltransferases; Animals; Fatty Acid Elongases; Fatty Acid Synthases; Fem | 2013 |
[Fibrate-induced changes in the serum lipid contents of individual C16 and C18 fatty acids in patients with hyperlipidemia].
Topics: Fatty Acids; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Linoleic Acid; Lipids; Olei | 2006 |