stearic acid has been researched along with Diabetes Mellitus, Adult-Onset in 13 studies
octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found strong positive relationships between adipose tissue TG content of the fatty acids myristic acid (14:0) and stearic acid (18:0) with insulin sensitivity (HOMA model) (p < 0." | 3.75 | Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans. ( Dennis, AL; Frayn, KN; Harnden, KE; Hodson, L; Humphreys, SM; Micklem, KJ; Neville, MJ; Roberts, R, 2009) |
| "A total of 15 NIDDM patients participated in a randomized crossover study with three 3-week diet interventions separated by 2-week washout periods." | 2.68 | Comparison of a carbohydrate-rich diet and diets rich in stearic or palmitic acid in NIDDM patients. Effects on lipids, glycemic control, and diurnal blood pressure. ( Christiansen, C; Hermansen, K; Pedersen, E; Rasmussen, O; Storm, H; Thomsen, C, 1997) |
| "Obesity is the main risk factor for type 2 diabetes mellitus, and recent studies have shown that, in diet-induced obesity, the hypothalamus becomes inflamed and dysfunctional, resulting in the loss of the perfect coupling between caloric intake and energy expenditure." | 1.37 | Inflammation of the hypothalamus leads to defective pancreatic islet function. ( Araújo, EP; Boschero, AC; Calegari, VC; Morari, J; Sbragia, L; Torsoni, AS; Vanzela, EC; Velloso, LA; Zoppi, CC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, R | 2 |
| Yu, Y | 2 |
| Zhang, Y | 3 |
| Li, Y | 1 |
| Chu, X | 2 |
| Lu, H | 2 |
| Sun, C | 2 |
| Su, S | 1 |
| Zhao, Q | 1 |
| Shi, H | 1 |
| Sun, H | 1 |
| Li, S | 1 |
| Shi, D | 1 |
| Lin, JS | 2 |
| Dong, HL | 1 |
| Chen, GD | 1 |
| Chen, ZY | 1 |
| Dong, XW | 1 |
| Zheng, JS | 1 |
| Chen, YM | 1 |
| Huang, L | 1 |
| Aris, IM | 1 |
| Yang, G | 1 |
| Chen, WQ | 1 |
| Li, LJ | 1 |
| Sertoglu, E | 1 |
| Kurt, I | 1 |
| Tapan, S | 1 |
| Uyanik, M | 1 |
| Serdar, MA | 1 |
| Kayadibi, H | 1 |
| El-Fawaeir, S | 1 |
| Ma, W | 1 |
| Wu, JH | 2 |
| Wang, Q | 1 |
| Lemaitre, RN | 2 |
| Mukamal, KJ | 1 |
| Djoussé, L | 2 |
| King, IB | 2 |
| Song, X | 1 |
| Biggs, ML | 1 |
| Delaney, JA | 1 |
| Kizer, JR | 1 |
| Siscovick, DS | 1 |
| Mozaffarian, D | 2 |
| Zhao, L | 1 |
| Ni, Y | 1 |
| Ma, X | 1 |
| Zhao, A | 1 |
| Bao, Y | 1 |
| Liu, J | 1 |
| Chen, T | 1 |
| Xie, G | 1 |
| Panee, J | 1 |
| Su, M | 1 |
| Yu, H | 1 |
| Wang, C | 1 |
| Hu, C | 1 |
| Jia, W | 2 |
| Robinson, DM | 1 |
| Martin, NC | 1 |
| Robinson, LE | 1 |
| Ahmadi, L | 1 |
| Marangoni, AG | 1 |
| Wright, AJ | 1 |
| Roberts, R | 1 |
| Hodson, L | 1 |
| Dennis, AL | 1 |
| Neville, MJ | 1 |
| Humphreys, SM | 1 |
| Harnden, KE | 1 |
| Micklem, KJ | 1 |
| Frayn, KN | 1 |
| Calegari, VC | 1 |
| Torsoni, AS | 1 |
| Vanzela, EC | 1 |
| Araújo, EP | 1 |
| Morari, J | 1 |
| Zoppi, CC | 1 |
| Sbragia, L | 1 |
| Boschero, AC | 1 |
| Velloso, LA | 1 |
| Manichaikul, A | 1 |
| Guan, W | 1 |
| Tanaka, T | 1 |
| Foy, M | 1 |
| Kabagambe, EK | 1 |
| Siscovick, D | 1 |
| Fretts, AM | 1 |
| Johnson, C | 1 |
| Psaty, BM | 1 |
| McKnight, B | 1 |
| Rich, SS | 1 |
| Chen, YD | 1 |
| Nettleton, JA | 1 |
| Tang, W | 1 |
| Bandinelli, S | 1 |
| Jacobs, DR | 1 |
| Browning, BL | 1 |
| Laurie, CC | 1 |
| Gu, X | 1 |
| Tsai, MY | 1 |
| Steffen, LM | 1 |
| Ferrucci, L | 1 |
| Fornage, M | 1 |
| Armoni, M | 1 |
| Harel, C | 1 |
| Bar-Yoseph, F | 1 |
| Milo, S | 1 |
| Karnieli, E | 1 |
| Storm, H | 1 |
| Thomsen, C | 1 |
| Pedersen, E | 1 |
| Rasmussen, O | 1 |
| Christiansen, C | 1 |
| Hermansen, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Cardiovascular Health Study[NCT00005133] | 5,888 participants (Actual) | Observational | 1988-06-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for stearic acid and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Circulating Saturated Fatty Acids and Incident Type 2 Diabetes: A Systematic Review and Meta-Analysis.
Topics: Correlation of Data; Diabetes Mellitus, Type 2; Eicosanoic Acids; Fatty Acids; Humans; Incidence; My | 2019 |
3 trials available for stearic acid and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study.
Topics: Aged; Biomarkers; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follow | 2015 |
Influence of interesterification of a stearic acid-rich spreadable fat on acute metabolic risk factors.
Topics: Acute Disease; Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Cross-Over Studies; Diabe | 2009 |
Comparison of a carbohydrate-rich diet and diets rich in stearic or palmitic acid in NIDDM patients. Effects on lipids, glycemic control, and diurnal blood pressure.
Topics: Adult; Blood Glucose; Blood Pressure; Circadian Rhythm; Cohort Studies; Cross-Over Studies; Diabetes | 1997 |
9 other studies available for stearic acid and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Overexpression of miR-297b-5p protects against stearic acid-induced pancreatic β-cell apoptosis by targeting LATS2.
Topics: Animals; Apoptosis; Cell Line; Cells, Cultured; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterifie | 2020 |
Inhibition of lncRNA TCONS_00077866 Ameliorates the High Stearic Acid Diet-Induced Mouse Pancreatic β-Cell Inflammatory Response by Increasing miR-297b-5p to Downregulate SAA3 Expression.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Down-Regulation; Gene Expressio | 2021 |
Erythrocyte Saturated Fatty Acids and Incident Type 2 Diabetes in Chinese Men and Women: A Prospective Cohort Study.
Topics: Adult; Aged; China; Diabetes Mellitus, Type 2; Eicosanoic Acids; Erythrocytes; Fatty Acids; Female; | 2018 |
Comparison of plasma and erythrocyte membrane fatty acid compositions in patients with end-stage renal disease and type 2 diabetes mellitus.
Topics: Adult; Cell Membrane; Diabetes Mellitus, Type 2; Docosahexaenoic Acids; Erythrocyte Membrane; Fatty | 2014 |
A panel of free fatty acid ratios to predict the development of metabolic abnormalities in healthy obese individuals.
Topics: 8,11,14-Eicosatrienoic Acid; Adult; Arachidonic Acid; Area Under Curve; Body Mass Index; Cardiovascu | 2016 |
Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans.
Topics: Adipocytes; Adipose Tissue; Biopsy; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; | 2009 |
Inflammation of the hypothalamus leads to defective pancreatic islet function.
Topics: Animals; Diabetes Mellitus, Type 2; Dietary Fats; Hypothalamic Diseases; Hypothalamus; Inflammation; | 2011 |
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu
Topics: Adult; Aged; Chromosomes, Human, Pair 2; Cohort Studies; Coronary Disease; Delta-5 Fatty Acid Desatu | 2013 |
Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements.
Topics: Aged; Animals; Arachidonic Acid; Biopsy; Blotting, Western; Cell Nucleus; CHO Cells; Chromatography, | 2005 |