Page last updated: 2024-11-04

stearic acid and Cardiovascular Diseases

stearic acid has been researched along with Cardiovascular Diseases in 11 studies

octadecanoic acid : A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to determine the relative comparability of diets enriched in palmitic acid, stearic acid, and oleic acid on inflammation and coagulation markers, T lymphocyte proliferation/ex-vivo cytokine secretion, plasma cardiometabolic risk factors, and fecal bile acid concentrations."9.30Comparison of diets enriched in stearic, oleic, and palmitic acids on inflammation, immune response, cardiometabolic risk factors, and fecal bile acid concentrations in mildly hypercholesterolemic postmenopausal women-randomized crossover trial. ( Cohen, R; Dolnikowski, GG; Galluccio, JM; Li, L; Lichtenstein, AH; Matthan, NR; Meng, H; Rodríguez-Morató, J; Wu, D, 2019)
"The aim of this study was to determine the relative comparability of diets enriched in palmitic acid, stearic acid, and oleic acid on inflammation and coagulation markers, T lymphocyte proliferation/ex-vivo cytokine secretion, plasma cardiometabolic risk factors, and fecal bile acid concentrations."5.30Comparison of diets enriched in stearic, oleic, and palmitic acids on inflammation, immune response, cardiometabolic risk factors, and fecal bile acid concentrations in mildly hypercholesterolemic postmenopausal women-randomized crossover trial. ( Cohen, R; Dolnikowski, GG; Galluccio, JM; Li, L; Lichtenstein, AH; Matthan, NR; Meng, H; Rodríguez-Morató, J; Wu, D, 2019)
" Stearic acid induced significantly more EC apoptosis and necrosis than palmitic acid or myristic acids."3.76Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. ( Harvey, KA; Pavlina, TM; Siddiqui, RA; Walker, CL; Xu, Z; Zaloga, GP, 2010)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Gonçalinho, GHF1
Sampaio, GR1
Soares-Freitas, RAM1
Damasceno, NRT1
Lai, HTM1
de Oliveira Otto, MC1
Lee, Y1
Wu, JHY1
Song, X1
King, IB1
Psaty, BM1
Lemaitre, RN1
McKnight, B1
Siscovick, DS1
Mozaffarian, D1
Meng, H1
Matthan, NR1
Wu, D1
Li, L1
Rodríguez-Morató, J1
Cohen, R1
Galluccio, JM1
Dolnikowski, GG1
Lichtenstein, AH1
Zhao, L1
Ni, Y1
Ma, X1
Zhao, A1
Bao, Y1
Liu, J1
Chen, T1
Xie, G1
Panee, J1
Su, M1
Yu, H1
Wang, C1
Hu, C1
Jia, W2
Robinson, DM1
Martin, NC1
Robinson, LE1
Ahmadi, L1
Marangoni, AG1
Wright, AJ1
Harvey, KA1
Walker, CL1
Pavlina, TM1
Xu, Z1
Zaloga, GP1
Siddiqui, RA1
Karupaiah, T1
Tan, CH1
Chinna, K1
Sundram, K1
Steinberg, FM1
Bearden, MM1
Keen, CL1
Kris-Etherton, PM2
Griel, AE1
Psota, TL2
Gebauer, SK2
Zhang, J1
Etherton, TD1
Connor, WE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Dietary Fatty Acids on Cardiovascular Disease Risk Indicators and Inflammation.[NCT02145936]20 participants (Anticipated)Interventional2013-01-31Completed
Comparison of the Effect of Medium-Chain Fatty Acids and Long-Chain Fatty Acids on Postprandial Appetite and Lipemia[NCT05539742]26 participants (Actual)Interventional2022-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for stearic acid and Cardiovascular Diseases

ArticleYear
Cocoa and chocolate flavonoids: implications for cardiovascular health.
    Journal of the American Dietetic Association, 2003, Volume: 103, Issue:2

    Topics: Anticholesteremic Agents; Antioxidants; Biological Availability; Cacao; Cardiovascular Diseases; Chr

2003
Dietary stearic acid and risk of cardiovascular disease: intake, sources, digestion, and absorption.
    Lipids, 2005, Volume: 40, Issue:12

    Topics: Cardiovascular Diseases; Dietary Fats; Digestion; Eating; Humans; Intestinal Absorption; Risk Factor

2005
The diversity of health effects of individual trans fatty acid isomers.
    Lipids, 2007, Volume: 42, Issue:9

    Topics: Cardiovascular Diseases; Endothelium, Vascular; Food Industry; Food Labeling; Humans; Isomerism; Ste

2007

Trials

3 trials available for stearic acid and Cardiovascular Diseases

ArticleYear
Comparison of diets enriched in stearic, oleic, and palmitic acids on inflammation, immune response, cardiometabolic risk factors, and fecal bile acid concentrations in mildly hypercholesterolemic postmenopausal women-randomized crossover trial.
    The American journal of clinical nutrition, 2019, 08-01, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Cardiovascular Diseases; Cross-Over Studies; F

2019
Influence of interesterification of a stearic acid-rich spreadable fat on acute metabolic risk factors.
    Lipids, 2009, Volume: 44, Issue:1

    Topics: Acute Disease; Adult; Aged; Cardiovascular Diseases; Case-Control Studies; Cross-Over Studies; Diabe

2009
The chain length of dietary saturated fatty acids affects human postprandial lipemia.
    Journal of the American College of Nutrition, 2011, Volume: 30, Issue:6

    Topics: Adult; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Coconut Oil; Corn Oil; Cross-Ove

2011

Other Studies

5 other studies available for stearic acid and Cardiovascular Diseases

ArticleYear
Stearic Acid, but not Palmitic Acid, is Associated with Inflammatory and Endothelial Dysfunction Biomarkers in Individuals at Cardiovascular Risk.
    Arquivos brasileiros de cardiologia, 2023, Volume: 120, Issue:8

    Topics: Adult; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Female; Hea

2023
Serial Plasma Phospholipid Fatty Acids in the De Novo Lipogenesis Pathway and Total Mortality, Cause-Specific Mortality, and Cardiovascular Diseases in the Cardiovascular Health Study.
    Journal of the American Heart Association, 2019, 11-19, Volume: 8, Issue:22

    Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Cause of Death; Cohort Studies; Fatty Acids; Fatty

2019
A panel of free fatty acid ratios to predict the development of metabolic abnormalities in healthy obese individuals.
    Scientific reports, 2016, 06-27, Volume: 6

    Topics: 8,11,14-Eicosatrienoic Acid; Adult; Arachidonic Acid; Area Under Curve; Body Mass Index; Cardiovascu

2016
Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth.
    Clinical nutrition (Edinburgh, Scotland), 2010, Volume: 29, Issue:4

    Topics: Apoptosis; Cardiovascular Diseases; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Culture

2010
Harbingers of coronary heart disease: dietary saturated fatty acids and cholesterol. Is chocolate benign because of its stearic acid content?
    The American journal of clinical nutrition, 1999, Volume: 70, Issue:6

    Topics: Cacao; Cardiovascular Diseases; Cholesterol, Dietary; Cholesterol, LDL; Dietary Fats; Fatty Acids; H

1999