stearates and Leukemia-P388

stearates has been researched along with Leukemia-P388* in 1 studies

Other Studies

1 other study(ies) available for stearates and Leukemia-P388

ArticleYear
Studies on sucrose-palmitate-stearate-containing vesicles encapsulating the cytostatic drug methylglyoxal-bis-guanyl-hydrazone.
    Die Pharmazie, 1990, Volume: 45, Issue:10

    Vesicles prepared from sucrose-palmitate-stearate and cholesterol encapsulating the anticancer drug methylglyoxal-bis-guanylhydrazone, were investigated. Treatment with drug-loaded vesicles of this composition in a q.d. 1-4 schedule resulted for murine leukemias P388 in nearly the same increase in life span as the corresponding dose of the free drug. Even very high dosages of sucrose-palmitase-stearate (up to 480 mg.kg-1.d-1) were tolerated by mice.

    Topics: Animals; Capsules; Excipients; Female; Leukemia P388; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitoguazone; Palmitates; Stearates; Sucrose

1990