stearates and Hand-Dermatoses

stearates has been researched along with Hand-Dermatoses* in 2 studies

Other Studies

2 other study(ies) available for stearates and Hand-Dermatoses

Article	Year
Clinical efficacy evaluation of a novel barrier protection cream. Cutis, 2008, Volume: 82, Issue:4 Suppl COR806.805 (Tetrix Cream) is a new barrier cream formulated using a unique patented technology. As a water-in-oil emulsion, COR806.805 has a water-resistant outer surface and water-soluble inner surface. Clinical studies have demonstrated the safety of COR806.805 in healthy adults with respect to sensitization, irritation, and effect on the healing of existing skin lesions. We report the results of trials undertaken to explore the substantivity and barrier protection properties of this new product when applied to clinically normal skin, as well as the beneficial effects when applied to inflamed skin, including skin affected by eczema. The results indicate that the cream establishes a barrier against common irritants, with persistence over 6 hours. The product appears effective and well-tolerated as a barrier and also may provide benefit in managing the itching and burning associated with contact dermatitis. Topics: Adult; Allergens; Aluminum Hydroxide; Clinical Trials as Topic; Dermatitis, Contact; Dermatologic Agents; Emollients; Female; Hand Dermatoses; Humans; Magnesium Hydroxide; Siloxanes; Stearates	2008
Clinical safety evaluation of a novel barrier protection cream. Cutis, 2008, Volume: 82, Issue:4 Suppl Patients with contact dermatitis require both preventive and therapeutic interventions to minimize their burden of disease. The ideal product would support resolution of inflamed skin without the use of glucocorticoids while protecting undamaged skin against further contact with irritants and antigens. COR806.805 (Tetrix Cream) is a novel barrier cream formulated for use on both lesional and nonlesional skin. Three clinical trials were conducted to evaluate the safety of this new product by studying sensitization, cumulative irritation, and effect on healing; a combined total of 265 participants completed the studies (210, 45, and 10, respectively), with no serious adverse events considered to be related to the product. Six mild adverse events were considered related or potentially related. As tested, COR806.805 is neither sensitizing nor irritating when applied to intact or lesional skin. Testing indicates that COR806.805 does not inhibit healing of allergic contact dermatitis lesions. Topics: Adult; Allergens; Aluminum Hydroxide; Clinical Trials as Topic; Dermatitis, Contact; Dermatologic Agents; Emollients; Female; Hand Dermatoses; Humans; Magnesium Hydroxide; Siloxanes; Stearates	2008

Article

Year

Clinical efficacy evaluation of a novel barrier protection cream.

Cutis, 2008, Volume: 82, Issue:4 Suppl

COR806.805 (Tetrix Cream) is a new barrier cream formulated using a unique patented technology. As a water-in-oil emulsion, COR806.805 has a water-resistant outer surface and water-soluble inner surface. Clinical studies have demonstrated the safety of COR806.805 in healthy adults with respect to sensitization, irritation, and effect on the healing of existing skin lesions. We report the results of trials undertaken to explore the substantivity and barrier protection properties of this new product when applied to clinically normal skin, as well as the beneficial effects when applied to inflamed skin, including skin affected by eczema. The results indicate that the cream establishes a barrier against common irritants, with persistence over 6 hours. The product appears effective and well-tolerated as a barrier and also may provide benefit in managing the itching and burning associated with contact dermatitis.

Topics: Adult; Allergens; Aluminum Hydroxide; Clinical Trials as Topic; Dermatitis, Contact; Dermatologic Agents; Emollients; Female; Hand Dermatoses; Humans; Magnesium Hydroxide; Siloxanes; Stearates

2008

Clinical safety evaluation of a novel barrier protection cream.

Cutis, 2008, Volume: 82, Issue:4 Suppl

Patients with contact dermatitis require both preventive and therapeutic interventions to minimize their burden of disease. The ideal product would support resolution of inflamed skin without the use of glucocorticoids while protecting undamaged skin against further contact with irritants and antigens. COR806.805 (Tetrix Cream) is a novel barrier cream formulated for use on both lesional and nonlesional skin. Three clinical trials were conducted to evaluate the safety of this new product by studying sensitization, cumulative irritation, and effect on healing; a combined total of 265 participants completed the studies (210, 45, and 10, respectively), with no serious adverse events considered to be related to the product. Six mild adverse events were considered related or potentially related. As tested, COR806.805 is neither sensitizing nor irritating when applied to intact or lesional skin. Testing indicates that COR806.805 does not inhibit healing of allergic contact dermatitis lesions.

2008