stavudine has been researched along with HIV in 121 studies
*HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. [MeSH]
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (7.44) | 18.7374 |
1990's | 38 (31.40) | 18.2507 |
2000's | 48 (39.67) | 29.6817 |
2010's | 24 (19.83) | 24.3611 |
2020's | 2 (1.65) | 2.80 |
Authors | Studies |
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Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E | 1 |
Augustyns, K; Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Janssen, G; Jie, L; Peeters, O; Van Aerschot, A | 1 |
August, EM; Brankovan, V; Ghazzouli, I; Hitchcock, MJ; Lin, TS; Mansuri, MM; Prusoff, WH; Sommadossi, JP; Starrett, JE; Sterzycki, RZ | 1 |
Broder, S; Driscoll, JS; Kim, CH; Marquez, VE; Mitsuya, H | 1 |
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H | 1 |
Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH | 1 |
Balzarini, J; Cahard, D; De Clercq, E; McGuigan, C; Sheeka, HM | 1 |
Baba, M; Cheng, YC; Dutschman, GE; Grill, SP; Hu, R; Lam, W; Paintsil, E; Tanaka, H | 1 |
Abdullahi, A; Austin, H; Azumah, M; Chadwick, D; Geretti, AM; Owusu, D; Phillips, RO; Phillips, S; Sayeed, L; Smith, C; Villa, G | 1 |
Cassim, H; Gray, GE; Greeff, OBW; Lazarus, E; Liberty, A; Otwombe, K; Violari, A | 1 |
Alfredo, C; Auld, A; Bhatt, N; Bila, D; Buck, WC; Cossa, L; DeVos, J; Houston, J; Jani, I; Jobarteh, K; Macassa, E; Sabatier, J; Sousa, A; Vaz, P; Yang, C | 1 |
Kan, W; Leng, X; Liao, L; Liu, P; Ruan, Y; Shao, Y; Wang, J; Xing, H; Xu, W; Yan, J; You, Y; Zuo, Z | 1 |
Arnett, DK; Bagchi, S; Chi, BH; Heimburger, DC; Kabagambe, EK; Kiage, JN; Koethe, JR; Nyirenda, CK; Wellons, MF | 1 |
Charalambous, S; Churchyard, GJ; Grant, AD; Hoffmann, CJ; Lewis, JJ; Velen, K | 1 |
Dandara, C; Kampira, E; Kumwenda, J; Van Oosterhout, JJ | 1 |
Cotton, MF; Derendorf, H; Innes, S; Rosenkranz, B; Sy, SK | 1 |
Coovadia, A; Cox, V; Davies, MA; Eley, B; Kuhn, L; Moultrie, H; Muchiri, E; Rabie, H; Schomaker, M; Technau, KG; Vizcaya, LS; Wood, R | 1 |
Holla, P; Jameel, S; Munshi, SU; Panda, H; Rewari, BB | 1 |
Boettiger, DC; Chaiwarith, R; Choi, JY; Ditangco, R; Kamarulzaman, A; Kantipong, P; Kerr, S; Kiertiburanakul, S; Kumarasamy, N; Law, M; Lee, C; Li, CK; Merati, TP; Mustafa, M; Ng, OT; Oka, S; Pham, TT; Pujari, S; Ratanasuwan, W; Sohn, A; Van Kinh, N; Vonthanak, S; Wong, WW; Yunihastuti, E; Zhang, F | 1 |
Bartlett, JA; Crump, JA; Grossmann, H; Masenga, EJ; Mavura, DR; Minja, E | 1 |
Chim, B; Choun, K; Lorent, N; Lynen, L; Thai, S; van Griensven, J | 1 |
Cai, W; Caughey, B; Chung, C; Dai, Z; Hu, F; Lan, Y; Li, L; Tang, X; Zhang, K | 1 |
Belyhun, Y; Liebert, UG; Maier, M | 1 |
Boulle, A; Cohen, K; Davies, MA; de Waal, R; Fortuin-de Smidt, M; Igumbor, EU; Maartens, G; Stinson, K; Technau, KG | 1 |
Ananworanich, J; Chetchotisakd, P; Gayet-Ageron, A; Hirschel, B; Jupimai, T; Kiertiburanakul, S; LeBraz, M; Munsakul, W; Prasithsirikul, W; Raksakulkarn, P; Ruxrungtham, K; Schutz, M; Tansuphasawadikul, S; Ubolyam, S | 1 |
Kumar, V; Malhotra, SV | 1 |
Bruun, J; Clotet, B; Cozzi-Lepri, A; Eg Hansen, AB; Horban, A; Katlama, C; Lundgren, JD; Martinez-Picado, J; Monforte, Ad; Phillips, AN | 1 |
Crowther, NJ; George, JA; Van Deventer, HE; Venter, WD | 1 |
Amuron, B; Birungi, J; Bunnell, R; Coutinho, A; Foster, S; Grosskurth, H; Jaffar, S; Kyomuhangi, R; Levin, J; Mermin, J; Nabiryo, C; Namara, G; Ndembi, N; Opio, A; Tappero, JW | 1 |
Corbett, AH; Hosseinipour, MC; Kanyama, C; Kashuba, AD; Kazembe, P; Mkupani, P; Mwansambo, C; Nyirenda, J; Rezk, NL; Sichali, D; Tien, H; Weigel, R | 1 |
Aghafar, Z; Cherry, CL; Chew, CS; Gut, I; Imran, D; Ismail, R; Kamarulzaman, A; Phipps, M; Price, P; Varna, S; Yunihastuti, E | 1 |
Bachani, D; Chan, PL; Deshpande, A; Rajasekaran, S; Rewari, BB; Srikantiah, P | 1 |
Dhlomo, S; Emery, S; Grandits, G; Khabo, P; Khanyile, T; Komati, S; Magongoa, D; Naidoo, LC; Neaton, JD; Polis, M; Qolohle, D; Ratsela, A | 1 |
Biwolé-Sida, M; Bork, K; Coudray, M; Cournil, A; Delaporte, E; Essomba, CN; Kouanfack, C; Laurent, C; Tonfack, CA | 1 |
Ekwunife, OI; Iwuamadi, UI; Udeogaranya, OP; Ukwe, CV | 1 |
Shegokar, R; Singh, KK | 1 |
Kuo, YC; Lee, CL | 1 |
Fox, MP; Maotoe, T; Maskew, M; Sanne, IM; Westreich, D | 1 |
Bonovas, S; Hatzakis, A; Nikolopoulos, G; Tsiodras, S | 1 |
Balzarini, J; Ducho, C; Meiera, C; Renzea, J | 1 |
Biasin, M; Clerici, M; Di Pietro, M; Lo Caputo, S; Maserati, R; Mazzotta, F; Ravasi, G; Seminari, E; Trabattoni, D | 1 |
Antonelli, G; Bambacioni, F; Bellomi, F; Focher, F; Gentile, M; Scagnolari, C; Turriziani, O | 1 |
Livrozet, JM; Miossec, P; Touraine, JL; Wegrzyn, J | 1 |
Chen, C; Pendergrass, S; Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK | 1 |
Aboulker, JP; Brun-Vézinet, F; Descamps, D; Flandre, P; Harel, M; Izopet, J; Joly, V; Lastère, S; Meiffrédy, V; Peytavin, G; Tamalet, C; Yéni, P; Zeng, AF | 1 |
Piliero, P; Sanne, I; Schnittman, S; Squires, K; Thiry, A | 1 |
Bernard, N; Beylot, J; Bonarek, M; Bonnet, F; Dupon, M; Gemain, MC; Malvy, D; Mercié, P; Morlat, P; Pellegrin, JL | 1 |
D'Cruz, OJ; Samuel, P; Uckun, FM; Waurzyniak, B | 1 |
Fisher, RL; Hernandez, JE; Hessenthaler, SM; Lonergan, JT; McComsey, GA; Sension, MG; Shalit, P; Ward, DJ; Williams, VC | 1 |
Pendergrass, S; Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
Brew, BJ; Pemberton, L; Ray, J | 1 |
D'Cruz, OJ; Uckun, FM | 1 |
Calvo, KC; Koser, GF; Wang, X | 1 |
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M | 1 |
Burchett, SK; Ciupak, G; Delke, I; Frenkel, L; Hitti, J; Huang, S; Mathias, A; Mofenson, L; Rathore, M; Samelson, R; Shapiro, DE; Smith, ME; Unadkat, JD; Wade, NA; Watts, DH; Yasin, S | 1 |
Aarnoutse, RE; Burger, DM; Verweij-van Wissen, CP | 1 |
Havlir, DV; Ignacio, CC; Koelsch, KK; Lu, B; Margot, N; Miller, MD; Strain, MC; Wong, JK | 1 |
Asmuth, D; Bakare, N; Blick, G; Farthing, C; Foli, A; Frank, I; Greiger, P; Groff, A; Herman, D; Lisziewicz, J; Lori, F; Lova, L; Norris, D; Peterson, D; Pollard, RB; Rashbaum, B; Schrader, S; Shalit, P; Tennenberg, A; Whitman, L | 1 |
Baba, M; Cheng, YC; Dutschman, GE; Haraguchi, K; Nitanda, T; Sumino, M; Takeda, S; Tanaka, H | 1 |
Engels, JW; Lazrek, HB; Rochdi, A; Taourirte, M; Vasseur, JJ | 1 |
Balzarini, J; Böge, NP; Meier, C; Vukadinović, D | 1 |
Qazi, S; Uckun, FM; Venkatachalam, TK | 1 |
Calia, GM; Chessa, F; Falchi, A; Lovigu, C; Madeddu, G; Mannazzu, M; Mura, MS; Solinas, P; Spanu, A | 1 |
Andreotti, M; Ceffa, S; Cusato, M; Germano, P; Giuliano, M; Guidotti, G; Liotta, G; Loureiro, S; Mancini, MG; Marazzi, MC; Palombi, L; Pirillo, MF; Regazzi, M; Vella, S; Villani, P | 1 |
Carvalho, AT; Fernandes, PA; Ramos, MJ | 1 |
Bacchetti, P; Gripshover, B; Kotler, D; Overton, ET; Rimland, D; Tien, PC | 1 |
DuMez, D; Qazi, S; Tibbles, H; Uckun, FM; Venkatachalam, TK | 1 |
Dubé, MP; Grinspoon, SK; Komarow, L; Mulligan, K; Parker, RA; Robbins, GK; Roubenoff, R; Tebas, P | 1 |
Arnaiz, JA; Blanco, JL; de Lazzari, E; Garrabou, G; Gatell, JM; Laguno, M; Larrousse, M; Leon, A; Lonca, M; López, S; Mallolas, J; Martinez, E; Milinkovic, A; Miró, O; Vidal, S | 1 |
Anderson, AM; Bartlett, JA; Kosinski, AS | 1 |
Aubertin, AM; Fossey, C; Huynh, NT; Laduree, D; Laumond, G; Schmidt, S; Vidu, A; Vu, AH; Zarafu, I | 1 |
Blaxhult, A; Lundgren, JD; Mocroft, A; Olsen, CH; Panos, G; Smith, CJ; Staszewski, S; Staub, T; Vetter, N; Viard, JP | 1 |
Baba, M | 1 |
Hansen, JE; Mathiesen, LR; Nielsen, C; Nielsen, JO; Sørensen, AM | 1 |
Anderson, RE; Cross, A; Dunkle, LM; Follansbee, S; Hardy, WD; Petersen, EA; Peterson, DM; Ramírez-Ronda, CH; Sacks, HS; Schwartz, R | 1 |
Lüthy, R | 1 |
Bauer, G; Bilello, JA; Cole, GA; Drusano, GL; Dudley, MN | 1 |
Magnuson, T; Mourton, T; Toltzis, P | 1 |
Ghazzouli, I; Hitchcock, MJ; Mansuri, MM; Martin, JC; Russell, JW; Starrett, JE; Tortolani, DR; Whiterock, VJ | 1 |
Cretton, EM; Hitchcock, MJ; Kaul, S; Kidd, LB; McClure, HM; Sommadossi, JP; Zhou, Z | 1 |
Dandekar, KA; Kaul, S | 1 |
Ahluwalia, GS; Gao, WY; Johns, DG; Mitsuya, H | 1 |
Ho, DD | 1 |
al-Mulla, W; Church, D; Gill, MJ | 1 |
Collins, DO; Sakamoto, A | 1 |
Balzarini, J; Bidois, L; Cahard, D; De Clercq, E; McGuigan, C; Naesens, L; Salgado, A; Tsang, HW; Turner, K; Velazquez, S | 1 |
Kaiser, R; Rockstroh, JK; Sauerbruch, T; Spengler, U; Theisen, A | 1 |
de Jong, JJ; de Wolf, F; Foudraine, NA; Jan Weverling, G; Jurriaans, S; Keet, IP; Lange, JM; Maas, J; Roos, MT; van Benthem, BH; Vandermeulen, K | 1 |
Brown, SL; Melbourne, KM; Silverblatt, FJ | 1 |
Abrams, EJ; Culnane, M; Diaz, C; Gwynne, M; Kline, MW; Lindsey, JC; McKinney, RE; Mofenson, LM; Van Dyke, RB; Yogev, R | 1 |
Balzarini, J; Cahard, D; De Clercq, E; McGuigan, C; Naesens, L; Pathirana, R; Saboulard, D; Salgado, A; Velazquez, S | 1 |
Medina, DJ; Strair, RK; Tung, PP | 1 |
Beall, G; Cross, AP; Dunkle, LM; Gathe, J; Hardy, D; Murphy, RL; Peterson, D; Pollard, RB; Pottage, J; Reynolds, L; Rutkievicz, V | 1 |
Alvarez, A; Barreiro, P; Briones, C; de Mendoza, C; Gallego, O; González-Lahoz, J; Soriano, V | 1 |
Boschini, A; Calista, D | 1 |
Fife, KH; Fox, L; Friedland, GH; Havlir, DV; Kessler, H; Pollard, RB; Richman, DD; Smeaton, L; Sommadossi, JP; Tierney, C | 1 |
Adler, M; Cross, AP; Dunkle, LM; Elion, R; Kaul, S; Kelleher, T; Knupp, C | 1 |
Arnedo, A; Gómez, CJ; Roca, B | 1 |
Antela, A; Casado, JL; Dehertogh, P; Dronda, F; Hertogs, K; Martí-Belda, P; Moreno, S; Sabido, R | 1 |
Conant, M | 1 |
Torres, G | 1 |
Smart, T | 1 |
James, JS | 1 |
Jiricny, J | 1 |
Bartlett, JA; Bucy, RP; Fiscus, SA; Gryszowska, V; Miralles, GD; Ottinger, J; Pruitt, SK; Sevin, AD; Silberman, M | 1 |
Peck, A; Schinazi, RF; Sommadossi, JP | 1 |
Barbhaiya, RH; Dandekar, KA; Janiszewski, JS; Kaul, S; Mulvana, DE | 1 |
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R | 1 |
Harte, WE; Mansuri, MM; Martin, JC; Starrett, JE | 1 |
Chen, CH; Cheng, YC; Vazquez-Padua, M | 1 |
Dunkle, LM; Fridland, A; Ghazzouli, I; Hitchcock, MJ; Kaul, S; Mansuri, MM; Martin, JC; Sterzycki, RZ | 1 |
Lin, TS; Prusoff, WH; Schinazi, RF | 1 |
Balzarini, J; De Clercq, E; Herdewijn, P | 1 |
August, EM; Lin, TS; Marongiu, ME; Prusoff, WH | 1 |
Baba, M; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Vandeputte, M | 1 |
Hamamoto, Y; Matsuda, A; Matsui, T; Nakashima, H; Ueda, T; Yamamoto, N | 1 |
5 review(s) available for stavudine and HIV
Article | Year |
---|---|
Antiretrovirals for HIV Exposure Prophylaxis.
Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine | 2012 |
cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.
Topics: Antiviral Agents; Benzyl Alcohols; Biotransformation; Dideoxynucleotides; HIV; Humans; Prodrugs; Stavudine; Structure-Activity Relationship; Thymine Nucleotides | 2002 |
[Antiretroviral therapy. Current status and perspectives].
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Stavudine; Zalcitabine; Zidovudine | 1994 |
Targeted therapy of human immunodeficiency virus-related disease.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine | 1991 |
Comparative studies of 2',3'-didehydro-2',3'-dideoxythymidine (D4T) with other pyrimidine nucleoside analogues.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Dideoxynucleosides; HIV; Humans; Stavudine | 1990 |
23 trial(s) available for stavudine and HIV
Article | Year |
---|---|
Long-term efficacy and safety of first-line therapy with once-daily saquinavir/ritonavir.
Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Combinations; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Hyperlipidemias; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Thailand; Time Factors; Treatment Outcome; Viral Load | 2008 |
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine | 2009 |
Pharmacokinetics of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian children.
Topics: Adolescent; Anti-HIV Agents; Body Weight; Child; Child, Preschool; Cross-Over Studies; Dosage Forms; Drug Administration Schedule; Drugs, Generic; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Malawi; Male; Nevirapine; Prospective Studies; Stavudine | 2010 |
A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa.
Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; RNA, Viral; South Africa; Stavudine; Treatment Outcome; Zidovudine | 2010 |
Modulation of human immunodeficiency virus (HIV)-specific immune response by using efavirenz, nelfinavir, and stavudine in a rescue therapy regimen for HIV-infected, drug-experienced patients.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4-Positive T-Lymphocytes; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interferon-gamma; Interleukin-10; Interleukin-2; Male; Nelfinavir; Oxazines; Random Allocation; RNA, Messenger; Stavudine; Treatment Failure | 2002 |
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.
Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mutation; Patient Compliance; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2002 |
Results of a phase 2 clinical trial at 48 weeks (AI424-007): a dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naive subjects.
Topics: Adult; Atazanavir Sulfate; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lipids; Nelfinavir; Oligopeptides; Pyridines; RNA, Viral; Stavudine; Time Factors; Viral Load | 2003 |
Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Female; HIV; HIV Infections; HIV-1; Humans; Lipodystrophy; Male; Middle Aged; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2004 |
Pharmacokinetics and safety of stavudine in HIV-infected pregnant women and their infants: Pediatric AIDS Clinical Trials Group protocol 332.
Topics: Adult; Amniotic Fluid; Anti-HIV Agents; Area Under Curve; Drug Therapy, Combination; Female; Half-Life; HIV; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Metabolic Clearance Rate; Pregnancy; Pregnancy Complications, Infectious; Stavudine; Viral Load | 2004 |
Lowering the dose of hydroxyurea minimizes toxicity and maximizes anti-HIV potency.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Hydroxyurea; Male; RNA, Viral; Stavudine; Viral Load; Viremia | 2005 |
Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV; HIV Infections; Humans; Lamivudine; Milk, Human; Nevirapine; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; RNA, Viral; Stavudine; Zidovudine | 2007 |
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.
Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Composition; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Prospective Studies; Stavudine; Time Factors; Treatment Outcome; United States; Zidovudine | 2007 |
The impact of reducing stavudine dose versus switching to tenofovir on plasma lipids, body composition and mitochondrial function in HIV-infected patients.
Topics: Adenine; Adult; Anti-HIV Agents; Body Composition; Cholesterol; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Lipodystrophy; Male; Middle Aged; Mitochondria; Organophosphonates; Oxygen Consumption; Stavudine; Tenofovir; Treatment Outcome; Triglycerides | 2007 |
Dose-related activity of stavudine in patients infected with human immunodeficiency virus.
Topics: Adult; Aged; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; HIV; HIV Core Protein p24; HIV Infections; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Stavudine; Survival Analysis; Weight Gain | 1995 |
An open randomized controlled trial of zidovudine plus lamivudine versus stavudine plus lamivudine.
Topics: Adult; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Homosexuality, Male; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1998 |
Combination therapy with stavudine (d4T) plus didanosine (ddI) in children with human immunodeficiency virus infection. The Pediatric AIDS Clinical Trials Group 327 Team.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infant; Male; RNA, Viral; Statistics, Nonparametric; Stavudine | 1999 |
Safety and antiretroviral effects of combined didanosine and stavudine therapy in HIV-infected individuals with CD4 counts of 200 to 500 cells/mm3.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; RNA, Viral; Stavudine; Viral Load; Virus Replication; Weight Gain | 1999 |
In vivo antagonism with zidovudine plus stavudine combination therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; RNA, Viral; Stavudine; Zidovudine | 2000 |
The safety profile and antiviral activity of the combination of stavudine, didanosine, and nelfinavir in patients with HIV infection.
Topics: Administration, Oral; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Nelfinavir; RNA, Viral; Safety; Stavudine; Treatment Outcome; Viral Load | 1999 |
Efficacy, tolerance, and pharmacokinetics of the combination of stavudine, nevirapine, nelfinavir, and saquinavir as salvage regimen after ritonavir or indinavir failure.
Topics: Adult; Aged; Anti-HIV Agents; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Indinavir; Male; Middle Aged; Mutation; Nelfinavir; Nevirapine; Prospective Studies; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Treatment Failure; Viral Load | 2001 |
Phase II/III Trials of Viracept start.
Topics: Anti-HIV Agents; Blood; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Pilot Projects; Reverse Transcriptase Inhibitors; Stavudine; Sulfonic Acids; Time Factors; Zidovudine | 1996 |
Reappraising d4T.
Topics: CD4 Lymphocyte Count; HIV; HIV Infections; Humans; Randomized Controlled Trials as Topic; Stavudine; Zidovudine | 1995 |
Addition of cyclophosphamide to antiretroviral therapy does not diminish the cellular reservoir in HIV-infected persons.
Topics: Adolescent; Adult; CD4 Lymphocyte Count; Cyclophosphamide; DNA, Viral; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lymphoid Tissue; Male; Middle Aged; Monocytes; Nelfinavir; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load | 2002 |
93 other study(ies) available for stavudine and HIV
Article | Year |
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Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Kinetics; Molecular Structure; Phosphorylation; Pyrimidine Nucleosides; Rabbits; Stavudine; T-Lymphocytes; Thymidine Kinase; Thymus Gland; Zidovudine | 1990 |
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Molecular Conformation; X-Ray Diffraction | 1990 |
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent.
Topics: Antiviral Agents; Bone Marrow; Dideoxynucleosides; HIV; Stavudine; Thymidine; Zidovudine | 1989 |
Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogues.
Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemical Phenomena; Chemistry; Deoxycytidine; HIV; Structure-Activity Relationship; T-Lymphocytes, Helper-Inducer; Zalcitabine | 1987 |
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication | 1987 |
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship | 1987 |
Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.
Topics: 3T3 Cells; Animals; Antiviral Agents; HIV; Mice; Phosphates; Stavudine; Structure-Activity Relationship | 1996 |
Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
Topics: Anti-HIV Agents; Cell Line; Dideoxynucleotides; Dose-Response Relationship, Drug; HeLa Cells; HIV; Humans; Phosphorylation; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Virus Replication; Zidovudine | 2007 |
Liver steatosis and fibrosis in people with human immunodeficiency virus in West Africa and the relationship with hepatitis B virus coinfection.
Topics: Adult; Coinfection; Fatty Liver; Female; Ghana; Hepatitis B; Hepatitis B virus; HIV; HIV Infections; Humans; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; RNA; Stavudine | 2022 |
A retrospective case-cohort study comparing treatment outcomes in abacavir versus stavudine containing first line antiretroviral treatment regimens in children <3yrs old, at a paediatric programme based in Soweto, South Africa.
Topics: Child, Preschool; Dideoxynucleosides; Drug Combinations; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Lopinavir; Male; Retrospective Studies; Ritonavir; South Africa; Stavudine; Treatment Outcome; Viral Load | 2017 |
Compromise of Second-Line Antiretroviral Therapy Due to High Rates of Human Immunodeficiency Virus Drug Resistance in Mozambican Treatment-Experienced Children With Virologic Failure.
Topics: Adolescent; Anti-Retroviral Agents; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Mozambique; Nevirapine; Stavudine; Treatment Failure; Viral Load | 2020 |
Adherence, virological outcome, and drug resistance in Chinese HIV patients receiving first-line antiretroviral therapy from 2011 to 2015.
Topics: Adult; Anti-HIV Agents; China; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Retrospective Studies; Stavudine; Sustained Virologic Response; Tenofovir; Zidovudine | 2018 |
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine | 2013 |
Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Female; Health Resources; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Residence Characteristics; RNA, Viral; Stavudine; Tenofovir; Young Adult; Zidovudine | 2013 |
Mitochondrial subhaplogroups and differential risk of stavudine-induced lipodystrophy in Malawian HIV/AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; DNA, Mitochondrial; Female; Genetic Predisposition to Disease; Haplotypes; HIV; HIV Infections; Humans; Lipodystrophy; Male; Middle Aged; Mitochondria; Stavudine | 2013 |
Estimation of intracellular concentration of stavudine triphosphate in HIV-infected children given a reduced dose of 0.5 milligrams per kilogram twice daily.
Topics: Adult; Anti-HIV Agents; Child; Drug Administration Schedule; Drug Dosage Calculations; Female; HIV; HIV Infections; Humans; Male; Mitochondria; Models, Statistical; Stavudine | 2014 |
Virologic response in children treated with abacavir-compared with stavudine-based antiretroviral treatment: a South African multi-cohort analysis.
Topics: Adolescent; Anti-HIV Agents; Child; Cohort Studies; Dideoxynucleosides; Female; HIV; HIV Infections; Humans; Male; South Africa; Stavudine; Treatment Outcome; Viral Load | 2014 |
MicroRNA-150 is a potential biomarker of HIV/AIDS disease progression and therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Drug Resistance, Viral; Female; Gene Expression Regulation; HIV; Humans; Lamivudine; Leukocytes, Mononuclear; Male; MicroRNAs; Nevirapine; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2014 |
Trends in first-line antiretroviral therapy in Asia: results from the TREAT Asia HIV observational database.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Asia; Dideoxynucleosides; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine | 2014 |
Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Prospective Studies; RNA, Viral; Severity of Illness Index; Skin Diseases; Stavudine; Tanzania; Young Adult | 2015 |
Implementation of isoniazid preventive therapy in an HIV clinic in Cambodia: high rates of discontinuation when combined with antiretroviral therapy.
Topics: Adult; Ambulatory Care Facilities; Anti-HIV Agents; Antitubercular Agents; Cambodia; Drug Interactions; Female; HIV; HIV Infections; Humans; Isoniazid; Lamivudine; Male; Nevirapine; Opportunistic Infections; Patient Dropouts; Retrospective Studies; Stavudine; Tuberculosis | 2015 |
Plasma Mitochondrial DNA Levels as a Biomarker of Lipodystrophy Among HIV-infected Patients Treated with Highly Active Antiretroviral Therapy (HAART).
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; Case-Control Studies; Cyclopropanes; DNA, Mitochondrial; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Lopinavir; Male; Middle Aged; Mitochondria; Nelfinavir; Predictive Value of Tests; Ritonavir; ROC Curve; Stavudine; Zidovudine | 2015 |
HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Coinfection; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; Ethiopia; Female; Genetic Variation; Genome, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Immune Evasion; Lamivudine; Male; Mutation; Stavudine; Viral Load; Zidovudine | 2017 |
First-line antiretroviral drug discontinuations in children.
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Follow-Up Studies; HIV; HIV Infections; Humans; Infant; Kaplan-Meier Estimate; Lopinavir; Outcome Assessment, Health Care; Proportional Hazards Models; Ritonavir; South Africa; Stavudine; Withholding Treatment; Zidovudine | 2017 |
Synthesis of nucleoside-based antiviral drugs in ionic liquids.
Topics: Antiviral Agents; Bromodeoxyuridine; Chemistry, Pharmaceutical; Drug Design; HIV; Humans; Imidazoles; Ionic Liquids; Models, Chemical; Nucleosides; Simplexvirus; Solubility; Solvents; Stavudine; Trifluridine | 2008 |
Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Stavudine; Young Adult; Zidovudine | 2009 |
A longitudinal study of the changes in body fat and metabolic parameters in a South African population of HIV-positive patients receiving an antiretroviral therapeutic regimen containing stavudine.
Topics: Adipose Tissue; Adult; Anti-Retroviral Agents; Female; HIV; HIV Infections; Humans; Insulin; Lipids; Lipodystrophy; Longitudinal Studies; Male; Middle Aged; Risk Factors; South Africa; Stavudine | 2009 |
Tumour necrosis factor haplotypes associated with sensory neuropathy in Asian and Caucasian human immunodeficiency virus patients.
Topics: Anthropometry; Anti-HIV Agents; Asian People; Body Height; Genotype; Haplotypes; HIV; HIV Infections; Humans; Peripheral Nervous System Diseases; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Assessment; Risk Factors; Stavudine; Tumor Necrosis Factors; White People | 2011 |
Evaluating patients for second-line antiretroviral therapy in India: the role of targeted viral load testing.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine | 2010 |
Reduced dose of stavudine and lipoatrophy in HIV-infected patients in Cameroon.
Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Male; Middle Aged; Nevirapine; Stavudine; Zidovudine | 2010 |
Self-reported adherence to HAART in South-Eastern Nigeria is related to patients' use of pill box.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Algorithms; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Feasibility Studies; Female; HIV; HIV Infections; Humans; Lamivudine; Linear Models; Male; Medication Adherence; Middle Aged; Nevirapine; Nigeria; Patient Satisfaction; Prospective Studies; Reminder Systems; Risk Factors; Self Report; Stavudine; Surveys and Questionnaires; Treatment Outcome | 2010 |
Stavudine entrapped lipid nanoparticles for targeting lymphatic HIV reservoirs.
Topics: Animals; Anti-HIV Agents; Calorimetry, Differential Scanning; Cell Survival; Coloring Agents; Drug Compounding; Electrochemistry; Fluorescent Dyes; HIV; HIV Seropositivity; In Vitro Techniques; Lymphatic System; Macrophages; Male; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Particle Size; Rats; Rats, Wistar; Rhodamine 123; Stavudine; Tetrazolium Salts; Thiazoles; Tissue Distribution | 2011 |
Methylmethacrylate-sulfopropylmethacrylate nanoparticles with surface RMP-7 for targeting delivery of antiretroviral drugs across the blood-brain barrier.
Topics: Ammonium Sulfate; Anti-HIV Agents; Astrocytes; Biological Transport; Blood-Brain Barrier; Bradykinin; Cells, Cultured; Coculture Techniques; Delavirdine; Drug Carriers; Endothelial Cells; HIV; HIV Infections; Humans; Kinetics; Methacrylates; Microscopy, Electron, Scanning; Molecular Targeted Therapy; Nanoparticles; Particle Size; Permeability; Saquinavir; Stavudine | 2012 |
Effectiveness and safety of 30 mg versus 40 mg stavudine regimens: a cohort study among HIV-infected adults initiating HAART in South Africa.
Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cohort Studies; Dose-Response Relationship, Drug; Female; HIV; HIV Infections; Humans; Male; Prospective Studies; South Africa; Stavudine | 2012 |
Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine.
Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV; Humans; Phosphorylation; RNA, Messenger; Stavudine; T-Lymphocytes; Thymidine Kinase; Time Factors; Zidovudine | 2002 |
Rheumatoid arthritis after 9 years of human immunodeficiency virus infection: possible contribution of tritherapy.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Arthritis, Reactive; HIV; HIV Infections; Humans; Immunocompromised Host; Lamivudine; Male; Saquinavir; Stavudine; Treatment Outcome | 2002 |
Effects of aryl substituents on the anti-HIV activity of the arylphosphoramidate derivatives of stavudine.
Topics: Anti-HIV Agents; Cells, Cultured; HIV; Humans; Hydrogen-Ion Concentration; Hydrolysis; Leukocytes, Mononuclear; Molecular Structure; Stavudine; Virus Replication | 2002 |
Risk factors for lactic acidosis in HIV-infected patients treated with nucleoside reverse-transcriptase inhibitors: a case-control study.
Topics: Acidosis, Lactic; Adult; Case-Control Studies; Didanosine; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine | 2003 |
Development and evaluation of a thermoreversible ovule formulation of stampidine, a novel nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide.
Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Dideoxynucleotides; Drug Compounding; Drug Evaluation, Preclinical; Drug Stability; Female; HIV; Hydrogen-Ion Concentration; Hyperplasia; Kinetics; Rabbits; Solubility; Spermatocidal Agents; Stavudine; Thymidine Monophosphate; Vagina; Vaginitis | 2003 |
In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates.
Topics: Cells, Cultured; Dideoxynucleotides; Drug Resistance, Viral; Genotype; HIV; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Neutrophils; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate; Viral Plaque Assay; Zidovudine | 2004 |
Can the peripheral blood monocyte count be used as a marker of CSF resistance to antiretroviral drugs?
Topics: Anti-HIV Agents; Biomarkers; Buffers; Culture Media; Dideoxynucleosides; Drug Resistance, Viral; HIV; HIV Infections; Humans; In Vitro Techniques; Leukocyte Count; Monocytes; Stavudine; Zidovudine | 2004 |
Stampidine is a potential nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide.
Topics: Animals; Anti-HIV Agents; Biomechanical Phenomena; Cattle; Cervix Mucus; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Stability; Female; Fertility; Gels; HIV; Humans; Hydrogen-Ion Concentration; Male; Mucous Membrane; Pregnancy; Rabbits; Sperm Motility; Spermatozoa; Stavudine; Thymidine Monophosphate; Vagina | 2004 |
Bis-ketol nucleoside triesters as prodrugs of the antiviral nucleoside triphosphate analogues of 3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine.
Topics: Anti-HIV Agents; Cell Line; Esters; HIV; Humans; Molecular Structure; Nucleosides; Prodrugs; Stavudine; Thymidine | 2004 |
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine | 2004 |
Simultaneous determination of the HIV nucleoside analogue reverse transcriptase inhibitors lamivudine, didanosine, stavudine, zidovudine and abacavir in human plasma by reversed phase high performance liquid chromatography.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Drug Stability; HIV; HIV Infections; Humans; Lamivudine; Quality Control; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine | 2005 |
Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine.
Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; DNA, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Oxazines; RNA, Viral; Stavudine; Tenofovir; Viremia | 2005 |
A new approach to the synthesis of 4'-carbon-substituted nucleosides: development of a highly active anti-HIV agent 2', 3'-didehydro-3'-deoxy-4'-ethynylthymidine.
Topics: Anti-HIV Agents; Carbon; Cell Line; HIV; Humans; Inhibitory Concentration 50; Models, Chemical; Nucleosides; Oxygen; Stavudine | 2005 |
Homo and heterodimers of ddI, d4T and AZT: influence of (5'-5') thiolcabonate-carbamate linkage on anti-HIV activity.
Topics: Anti-HIV Agents; Antiviral Agents; Carbamates; Didanosine; Dimerization; HIV; HIV Infections; Models, Chemical; Molecular Conformation; Mutation; Stavudine; Sulfhydryl Compounds; Zidovudine | 2005 |
"Lock-in" modified cyclosal nucleotides--the second generation of cyclosal prodrugs.
Topics: Anti-HIV Agents; Binding Sites; Cell Line; Chemistry, Pharmaceutical; Dideoxynucleotides; Drug Design; Esterases; HIV; HIV Infections; Humans; Hydrolysis; Models, Chemical; Mutation; Nucleotides; Prodrugs; Protein Isoforms; Stavudine; Thymine Nucleotides | 2005 |
Synthesis, separation and anti-HIV activity of distereoisomers of N-[p-(4-bromophenyl) -2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine methyl ester (stampidine).
Topics: Anti-HIV Agents; Chemical Phenomena; Chemistry, Physical; Crystallization; Dideoxynucleotides; HIV; HIV-1; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Monocytes; Stavudine; Stereoisomerism; Structure-Activity Relationship; Thymidine Monophosphate | 2006 |
Thyroid function in human immunodeficiency virus patients treated with highly active antiretroviral therapy (HAART): a longitudinal study.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Autoantibodies; CD4 Lymphocyte Count; Epidemiologic Methods; Female; HIV; HIV Infections; Humans; Iodide Peroxidase; Male; Middle Aged; Stavudine; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 2006 |
Insights on resistance to reverse transcriptase: the different patterns of interaction of the nucleoside reverse transcriptase inhibitors in the deoxyribonucleotide triphosphate binding site relative to the normal substrate.
Topics: Binding Sites; Computer Simulation; Deoxyribonucleotides; Drug Resistance, Multiple, Viral; HIV; HIV Reverse Transcriptase; Humans; Molecular Conformation; Nucleosides; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zalcitabine | 2006 |
Association between hepatitis C virus coinfection and regional adipose tissue volume in HIV-infected men and women.
Topics: Adipose Tissue; Adult; Anti-HIV Agents; Body Fat Distribution; Cohort Studies; Cross-Sectional Studies; Female; Hepatitis C; HIV; HIV Infections; Humans; Lipodystrophy; Magnetic Resonance Imaging; Male; Middle Aged; Multivariate Analysis; Prevalence; RNA, Viral; Stavudine; Subcutaneous Fat | 2007 |
Anti-retroviral activity of GMP-grade stampidine against genotypically and phenotypically nucleoside reverse transcriptase inhibitor resistant recombinant human immunodeficiency virus. An in vitro study.
Topics: Anti-HIV Agents; Capsules; Chemistry, Pharmaceutical; Cloning, Molecular; Cytopathogenic Effect, Viral; Dideoxynucleotides; Drug Resistance, Viral; HIV; HIV-1; Humans; Mutation; Regression Analysis; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate | 2007 |
Decreasing CD4+ T-cell count during suppressed or low-level viraemia in patients with HIV infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Female; HIV; HIV Infections; Humans; Male; RNA, Viral; Stavudine; Viral Load; Viremia; Zidovudine | 2007 |
Synthesis and anti-HIV evaluation of hybrid-type prodrugs conjugating HIV integrase inhibitors with d4t by self-cleavable spacers containing an amino acid residue.
Topics: Alanine; Anti-HIV Agents; Cells, Cultured; Dimerization; HIV; HIV Integrase Inhibitors; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Prodrugs; Reverse Transcriptase Inhibitors; Stavudine | 2007 |
The role of antiretroviral therapy in the incidence of pancreatitis in HIV-positive individuals in the EuroSIDA study.
Topics: Adult; Anti-Retroviral Agents; Argentina; Case-Control Studies; CD4-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Europe; Female; HIV; HIV Infections; Humans; Incidence; Israel; Lymphopenia; Male; Middle Aged; Pancreatitis; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine | 2008 |
[Anti-HIV drug development: future prospect and problems].
Topics: Antiviral Agents; Carrier State; CD4 Antigens; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Oligonucleotides, Antisense; Reverse Transcriptase Inhibitors; Stavudine | 1993 |
Evaluation of the combination effect of different antiviral compounds against HIV in vitro.
Topics: Antiviral Agents; Benzodiazepines; Didanosine; Dideoxynucleosides; Drug Combinations; Drug Evaluation; Drug Synergism; HIV; Humans; Imidazoles; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1993 |
Effect of 2',3'-didehydro-3'-deoxythymidine in an in vitro hollow-fiber pharmacodynamic model system correlates with results of dose-ranging clinical studies.
Topics: Cell Line; DNA, Viral; Dose-Response Relationship, Drug; HIV; Humans; Models, Biological; Stavudine; Virus Replication | 1994 |
Comparative embryonic cytotoxicity of antiretroviral nucleosides.
Topics: Animals; Antiviral Agents; Culture Techniques; Didanosine; Embryo, Mammalian; HIV; Mice; Nucleosides; Stavudine; Zalcitabine; Zidovudine | 1994 |
Prodrugs of 2',3'-didehydro-3'-deoxythymidine (D4T): synthesis, antiviral activity, and rapid pharmacokinetic evaluation.
Topics: Animals; Antiviral Agents; Biological Availability; Chemical Phenomena; Chemistry, Physical; HIV; Leukemia Virus, Murine; Mice; Prodrugs; Stavudine | 1994 |
In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine.
Topics: Aminoisobutyric Acids; Animals; Antiviral Agents; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Feces; HIV; In Vitro Techniques; Injections, Intravenous; Injections, Subcutaneous; Liver; Macaca fascicularis; Macaca mulatta; Rats; Rats, Sprague-Dawley; Stavudine; Thymine; Zidovudine | 1993 |
Pharmacokinetics of the anti-human immunodeficiency virus nucleoside analog stavudine in cynomolgus monkeys.
Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Dideoxynucleosides; Half-Life; HIV; Humans; Macaca fascicularis; Male; Random Allocation; Stavudine | 1993 |
2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.
Topics: Amides; Biotransformation; Biphenyl Compounds; Cell Line; Deoxyguanosine; Floxuridine; HIV; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Kinetics; Methotrexate; Models, Biological; Phosphorylation; Pyrazoles; Reverse Transcriptase Inhibitors; Ribonucleosides; Ribose; RNA-Directed DNA Polymerase; Stavudine; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured | 1996 |
Therapy of HIV infections: problems and prospects.
Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Stavudine; Urban Health; Zalcitabine; Zidovudine | 1996 |
Phenotypic variations and switches in HIV isolated from the blood and the gastrointestinal tissues of patients with HIV-1 infection. HIV/GI Research Study Group.
Topics: Biopsy; Didanosine; Digestive System; Female; Giant Cells; HIV; HIV Enteropathy; HIV Infections; Humans; Male; Mutation; Phenotype; Prospective Studies; Stavudine; Viral Load; Zidovudine | 1997 |
Cure or control of HIV/AIDS?
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1997 |
Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.
Topics: Amides; Amino Acids; Animals; Cell Line; HIV; HIV-1; HIV-2; Humans; Mice; Organophosphates; Organophosphorus Compounds; Phosphoric Acids; Stavudine; Structure-Activity Relationship; Thymidine Kinase | 1997 |
Antiretroviral triple therapy decreases HIV viral load but does not alter hepatitis C virus (HCV) serum levels in HIV-HCV-co-infected haemophiliacs.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Hemophilia A; Hepacivirus; Hepatitis C; HIV; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1998 |
Gynecomastia with stavudine treatment in an HIV-positive patient.
Topics: Adult; Anti-HIV Agents; Gynecomastia; HIV; HIV Seropositivity; Humans; Male; Stavudine | 1998 |
Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
Topics: Amino Acids; Animals; Anti-HIV Agents; Biotransformation; Dideoxynucleotides; Drug Design; Esterases; Esters; HIV; Humans; Liver; Male; Mice; Nucleosides; Prodrugs; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Tumor Cells, Cultured; Zidovudine | 1999 |
Use of recombinant viruses to assess the pattern of early human immunodeficiency virus breakthrough infection in the presence of stavudine.
Topics: Animals; Anti-HIV Agents; COS Cells; Defective Viruses; Floxuridine; HeLa Cells; HIV; Humans; Jurkat Cells; Leukemia Virus, Murine; Recombination, Genetic; Stavudine; Zidovudine | 1999 |
Emergence of zidovudine resistance in HIV-infected patients receiving stavudine.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Stavudine; Zidovudine | 2000 |
Cutaneous side effects induced by indinavir.
Topics: Adult; Alopecia; Didanosine; Drug Eruptions; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Middle Aged; Pruritus; Pyoderma Gangrenosum; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Scalp Dermatoses; Skin; Stavudine; Zalcitabine; Zidovudine | 2000 |
Adherence, side effects and efficacy of stavudine plus lamivudine plus nelfinavir in treatment-experienced HIV-infected patients.
Topics: Adult; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Female; Hepatitis C; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Logistic Models; Male; Nelfinavir; Patient Compliance; Polymerase Chain Reaction; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Statistics, Nonparametric; Stavudine; Substance Abuse, Intravenous | 2000 |
Gene mutations identified.
Topics: Anti-HIV Agents; Computer Simulation; HIV; Humans; Models, Genetic; Mutation; Stavudine | 2001 |
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James.
Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1995 |
Protease inhibitor trials moving to next phase.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Nelfinavir; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication | 1995 |
Nipping HIV in the bud.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine | 1996 |
ddI plus d4T.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Stavudine | 1996 |
Hydroxyurea - new observations.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Indinavir; Nucleic Acid Synthesis Inhibitors; Stavudine; Viral Load; Virus Replication | 1998 |
Stavudine (Zerit).
Topics: Drug Resistance, Microbial; HIV; HIV Infections; Humans; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Stavudine | 2000 |
An APE that proofreads.
Topics: Anti-HIV Agents; Carbon-Oxygen Lyases; DNA; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Viral; Escherichia coli; HIV; Humans; Stavudine; Substrate Specificity; Zidovudine | 2002 |
Substrate specificity of Escherichia coli thymidine phosphorylase for pyrimidine nucleosides with anti-human immunodeficiency virus activity.
Topics: Antiviral Agents; Biological Availability; Deoxyuridine; Dideoxynucleosides; Emtricitabine; Escherichia coli; HIV; Pyrimidine Nucleosides; Stavudine; Substrate Specificity; Thymidine Phosphorylase; Zalcitabine | 1992 |
High-performance liquid chromatographic determination of 2',3'-didehydro-3'-deoxythymidine, a new anti-human immunodeficiency virus agent, in human plasma and urine.
Topics: Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Humans; Male; Reproducibility of Results; Spectrophotometry, Ultraviolet; Stavudine | 1992 |
Structural studies of the anti-HIV agent 2',3'-didehydro-2',3'-dideoxythymidine (D4T).
Topics: Antiviral Agents; Dideoxynucleosides; HIV; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Structure; Stavudine | 1991 |
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine | 1991 |
Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus.
Topics: Antiviral Agents; Deoxycytidine; HIV; Humans; Monocytes; Retroviridae Proteins; RNA-Directed DNA Polymerase; Stavudine; Thymidine; Virus Replication; Zidovudine | 1987 |
Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Deoxyribonucleotides; Dideoxynucleosides; Dose-Response Relationship, Drug; HIV; Humans; Mice; Phosphorylation; Sarcoma Viruses, Murine; Solubility; Stavudine; Thymidine; Zidovudine | 1989 |
Initial studies on the cellular pharmacology of 3'-deoxythymidin-2'-ene (d4T): a potent and selective inhibitor of human immunodeficiency virus.
Topics: Cell Division; Cell Line; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Humans; Stavudine; Virus Replication | 1988 |
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Structure-Activity Relationship; Thymidine; Virus Replication; Zidovudine | 1987 |
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.
Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Thymidine; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine | 1987 |