Page last updated: 2024-08-22

stavudine and HIV

stavudine has been researched along with HIV in 121 studies

*HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. [MeSH]

Research

Studies (121)

TimeframeStudies, this research(%)All Research%
pre-19909 (7.44)18.7374
1990's38 (31.40)18.2507
2000's48 (39.67)29.6817
2010's24 (19.83)24.3611
2020's2 (1.65)2.80

Authors

AuthorsStudies
Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E1
Augustyns, K; Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Janssen, G; Jie, L; Peeters, O; Van Aerschot, A1
August, EM; Brankovan, V; Ghazzouli, I; Hitchcock, MJ; Lin, TS; Mansuri, MM; Prusoff, WH; Sommadossi, JP; Starrett, JE; Sterzycki, RZ1
Broder, S; Driscoll, JS; Kim, CH; Marquez, VE; Mitsuya, H1
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H1
Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH1
Balzarini, J; Cahard, D; De Clercq, E; McGuigan, C; Sheeka, HM1
Baba, M; Cheng, YC; Dutschman, GE; Grill, SP; Hu, R; Lam, W; Paintsil, E; Tanaka, H1
Abdullahi, A; Austin, H; Azumah, M; Chadwick, D; Geretti, AM; Owusu, D; Phillips, RO; Phillips, S; Sayeed, L; Smith, C; Villa, G1
Cassim, H; Gray, GE; Greeff, OBW; Lazarus, E; Liberty, A; Otwombe, K; Violari, A1
Alfredo, C; Auld, A; Bhatt, N; Bila, D; Buck, WC; Cossa, L; DeVos, J; Houston, J; Jani, I; Jobarteh, K; Macassa, E; Sabatier, J; Sousa, A; Vaz, P; Yang, C1
Kan, W; Leng, X; Liao, L; Liu, P; Ruan, Y; Shao, Y; Wang, J; Xing, H; Xu, W; Yan, J; You, Y; Zuo, Z1
Arnett, DK; Bagchi, S; Chi, BH; Heimburger, DC; Kabagambe, EK; Kiage, JN; Koethe, JR; Nyirenda, CK; Wellons, MF1
Charalambous, S; Churchyard, GJ; Grant, AD; Hoffmann, CJ; Lewis, JJ; Velen, K1
Dandara, C; Kampira, E; Kumwenda, J; Van Oosterhout, JJ1
Cotton, MF; Derendorf, H; Innes, S; Rosenkranz, B; Sy, SK1
Coovadia, A; Cox, V; Davies, MA; Eley, B; Kuhn, L; Moultrie, H; Muchiri, E; Rabie, H; Schomaker, M; Technau, KG; Vizcaya, LS; Wood, R1
Holla, P; Jameel, S; Munshi, SU; Panda, H; Rewari, BB1
Boettiger, DC; Chaiwarith, R; Choi, JY; Ditangco, R; Kamarulzaman, A; Kantipong, P; Kerr, S; Kiertiburanakul, S; Kumarasamy, N; Law, M; Lee, C; Li, CK; Merati, TP; Mustafa, M; Ng, OT; Oka, S; Pham, TT; Pujari, S; Ratanasuwan, W; Sohn, A; Van Kinh, N; Vonthanak, S; Wong, WW; Yunihastuti, E; Zhang, F1
Bartlett, JA; Crump, JA; Grossmann, H; Masenga, EJ; Mavura, DR; Minja, E1
Chim, B; Choun, K; Lorent, N; Lynen, L; Thai, S; van Griensven, J1
Cai, W; Caughey, B; Chung, C; Dai, Z; Hu, F; Lan, Y; Li, L; Tang, X; Zhang, K1
Belyhun, Y; Liebert, UG; Maier, M1
Boulle, A; Cohen, K; Davies, MA; de Waal, R; Fortuin-de Smidt, M; Igumbor, EU; Maartens, G; Stinson, K; Technau, KG1
Ananworanich, J; Chetchotisakd, P; Gayet-Ageron, A; Hirschel, B; Jupimai, T; Kiertiburanakul, S; LeBraz, M; Munsakul, W; Prasithsirikul, W; Raksakulkarn, P; Ruxrungtham, K; Schutz, M; Tansuphasawadikul, S; Ubolyam, S1
Kumar, V; Malhotra, SV1
Bruun, J; Clotet, B; Cozzi-Lepri, A; Eg Hansen, AB; Horban, A; Katlama, C; Lundgren, JD; Martinez-Picado, J; Monforte, Ad; Phillips, AN1
Crowther, NJ; George, JA; Van Deventer, HE; Venter, WD1
Amuron, B; Birungi, J; Bunnell, R; Coutinho, A; Foster, S; Grosskurth, H; Jaffar, S; Kyomuhangi, R; Levin, J; Mermin, J; Nabiryo, C; Namara, G; Ndembi, N; Opio, A; Tappero, JW1
Corbett, AH; Hosseinipour, MC; Kanyama, C; Kashuba, AD; Kazembe, P; Mkupani, P; Mwansambo, C; Nyirenda, J; Rezk, NL; Sichali, D; Tien, H; Weigel, R1
Aghafar, Z; Cherry, CL; Chew, CS; Gut, I; Imran, D; Ismail, R; Kamarulzaman, A; Phipps, M; Price, P; Varna, S; Yunihastuti, E1
Bachani, D; Chan, PL; Deshpande, A; Rajasekaran, S; Rewari, BB; Srikantiah, P1
Dhlomo, S; Emery, S; Grandits, G; Khabo, P; Khanyile, T; Komati, S; Magongoa, D; Naidoo, LC; Neaton, JD; Polis, M; Qolohle, D; Ratsela, A1
Biwolé-Sida, M; Bork, K; Coudray, M; Cournil, A; Delaporte, E; Essomba, CN; Kouanfack, C; Laurent, C; Tonfack, CA1
Ekwunife, OI; Iwuamadi, UI; Udeogaranya, OP; Ukwe, CV1
Shegokar, R; Singh, KK1
Kuo, YC; Lee, CL1
Fox, MP; Maotoe, T; Maskew, M; Sanne, IM; Westreich, D1
Bonovas, S; Hatzakis, A; Nikolopoulos, G; Tsiodras, S1
Balzarini, J; Ducho, C; Meiera, C; Renzea, J1
Biasin, M; Clerici, M; Di Pietro, M; Lo Caputo, S; Maserati, R; Mazzotta, F; Ravasi, G; Seminari, E; Trabattoni, D1
Antonelli, G; Bambacioni, F; Bellomi, F; Focher, F; Gentile, M; Scagnolari, C; Turriziani, O1
Livrozet, JM; Miossec, P; Touraine, JL; Wegrzyn, J1
Chen, C; Pendergrass, S; Qazi, S; Samuel, P; Uckun, FM; Venkatachalam, TK1
Aboulker, JP; Brun-Vézinet, F; Descamps, D; Flandre, P; Harel, M; Izopet, J; Joly, V; Lastère, S; Meiffrédy, V; Peytavin, G; Tamalet, C; Yéni, P; Zeng, AF1
Piliero, P; Sanne, I; Schnittman, S; Squires, K; Thiry, A1
Bernard, N; Beylot, J; Bonarek, M; Bonnet, F; Dupon, M; Gemain, MC; Malvy, D; Mercié, P; Morlat, P; Pellegrin, JL1
D'Cruz, OJ; Samuel, P; Uckun, FM; Waurzyniak, B1
Fisher, RL; Hernandez, JE; Hessenthaler, SM; Lonergan, JT; McComsey, GA; Sension, MG; Shalit, P; Ward, DJ; Williams, VC1
Pendergrass, S; Qazi, S; Uckun, FM; Venkatachalam, TK1
Brew, BJ; Pemberton, L; Ray, J1
D'Cruz, OJ; Uckun, FM1
Calvo, KC; Koser, GF; Wang, X1
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M1
Burchett, SK; Ciupak, G; Delke, I; Frenkel, L; Hitti, J; Huang, S; Mathias, A; Mofenson, L; Rathore, M; Samelson, R; Shapiro, DE; Smith, ME; Unadkat, JD; Wade, NA; Watts, DH; Yasin, S1
Aarnoutse, RE; Burger, DM; Verweij-van Wissen, CP1
Havlir, DV; Ignacio, CC; Koelsch, KK; Lu, B; Margot, N; Miller, MD; Strain, MC; Wong, JK1
Asmuth, D; Bakare, N; Blick, G; Farthing, C; Foli, A; Frank, I; Greiger, P; Groff, A; Herman, D; Lisziewicz, J; Lori, F; Lova, L; Norris, D; Peterson, D; Pollard, RB; Rashbaum, B; Schrader, S; Shalit, P; Tennenberg, A; Whitman, L1
Baba, M; Cheng, YC; Dutschman, GE; Haraguchi, K; Nitanda, T; Sumino, M; Takeda, S; Tanaka, H1
Engels, JW; Lazrek, HB; Rochdi, A; Taourirte, M; Vasseur, JJ1
Balzarini, J; Böge, NP; Meier, C; Vukadinović, D1
Qazi, S; Uckun, FM; Venkatachalam, TK1
Calia, GM; Chessa, F; Falchi, A; Lovigu, C; Madeddu, G; Mannazzu, M; Mura, MS; Solinas, P; Spanu, A1
Andreotti, M; Ceffa, S; Cusato, M; Germano, P; Giuliano, M; Guidotti, G; Liotta, G; Loureiro, S; Mancini, MG; Marazzi, MC; Palombi, L; Pirillo, MF; Regazzi, M; Vella, S; Villani, P1
Carvalho, AT; Fernandes, PA; Ramos, MJ1
Bacchetti, P; Gripshover, B; Kotler, D; Overton, ET; Rimland, D; Tien, PC1
DuMez, D; Qazi, S; Tibbles, H; Uckun, FM; Venkatachalam, TK1
Dubé, MP; Grinspoon, SK; Komarow, L; Mulligan, K; Parker, RA; Robbins, GK; Roubenoff, R; Tebas, P1
Arnaiz, JA; Blanco, JL; de Lazzari, E; Garrabou, G; Gatell, JM; Laguno, M; Larrousse, M; Leon, A; Lonca, M; López, S; Mallolas, J; Martinez, E; Milinkovic, A; Miró, O; Vidal, S1
Anderson, AM; Bartlett, JA; Kosinski, AS1
Aubertin, AM; Fossey, C; Huynh, NT; Laduree, D; Laumond, G; Schmidt, S; Vidu, A; Vu, AH; Zarafu, I1
Blaxhult, A; Lundgren, JD; Mocroft, A; Olsen, CH; Panos, G; Smith, CJ; Staszewski, S; Staub, T; Vetter, N; Viard, JP1
Baba, M1
Hansen, JE; Mathiesen, LR; Nielsen, C; Nielsen, JO; Sørensen, AM1
Anderson, RE; Cross, A; Dunkle, LM; Follansbee, S; Hardy, WD; Petersen, EA; Peterson, DM; Ramírez-Ronda, CH; Sacks, HS; Schwartz, R1
Lüthy, R1
Bauer, G; Bilello, JA; Cole, GA; Drusano, GL; Dudley, MN1
Magnuson, T; Mourton, T; Toltzis, P1
Ghazzouli, I; Hitchcock, MJ; Mansuri, MM; Martin, JC; Russell, JW; Starrett, JE; Tortolani, DR; Whiterock, VJ1
Cretton, EM; Hitchcock, MJ; Kaul, S; Kidd, LB; McClure, HM; Sommadossi, JP; Zhou, Z1
Dandekar, KA; Kaul, S1
Ahluwalia, GS; Gao, WY; Johns, DG; Mitsuya, H1
Ho, DD1
al-Mulla, W; Church, D; Gill, MJ1
Collins, DO; Sakamoto, A1
Balzarini, J; Bidois, L; Cahard, D; De Clercq, E; McGuigan, C; Naesens, L; Salgado, A; Tsang, HW; Turner, K; Velazquez, S1
Kaiser, R; Rockstroh, JK; Sauerbruch, T; Spengler, U; Theisen, A1
de Jong, JJ; de Wolf, F; Foudraine, NA; Jan Weverling, G; Jurriaans, S; Keet, IP; Lange, JM; Maas, J; Roos, MT; van Benthem, BH; Vandermeulen, K1
Brown, SL; Melbourne, KM; Silverblatt, FJ1
Abrams, EJ; Culnane, M; Diaz, C; Gwynne, M; Kline, MW; Lindsey, JC; McKinney, RE; Mofenson, LM; Van Dyke, RB; Yogev, R1
Balzarini, J; Cahard, D; De Clercq, E; McGuigan, C; Naesens, L; Pathirana, R; Saboulard, D; Salgado, A; Velazquez, S1
Medina, DJ; Strair, RK; Tung, PP1
Beall, G; Cross, AP; Dunkle, LM; Gathe, J; Hardy, D; Murphy, RL; Peterson, D; Pollard, RB; Pottage, J; Reynolds, L; Rutkievicz, V1
Alvarez, A; Barreiro, P; Briones, C; de Mendoza, C; Gallego, O; González-Lahoz, J; Soriano, V1
Boschini, A; Calista, D1
Fife, KH; Fox, L; Friedland, GH; Havlir, DV; Kessler, H; Pollard, RB; Richman, DD; Smeaton, L; Sommadossi, JP; Tierney, C1
Adler, M; Cross, AP; Dunkle, LM; Elion, R; Kaul, S; Kelleher, T; Knupp, C1
Arnedo, A; Gómez, CJ; Roca, B1
Antela, A; Casado, JL; Dehertogh, P; Dronda, F; Hertogs, K; Martí-Belda, P; Moreno, S; Sabido, R1
Conant, M1
Torres, G1
Smart, T1
James, JS1
Jiricny, J1
Bartlett, JA; Bucy, RP; Fiscus, SA; Gryszowska, V; Miralles, GD; Ottinger, J; Pruitt, SK; Sevin, AD; Silberman, M1
Peck, A; Schinazi, RF; Sommadossi, JP1
Barbhaiya, RH; Dandekar, KA; Janiszewski, JS; Kaul, S; Mulvana, DE1
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R1
Harte, WE; Mansuri, MM; Martin, JC; Starrett, JE1
Chen, CH; Cheng, YC; Vazquez-Padua, M1
Dunkle, LM; Fridland, A; Ghazzouli, I; Hitchcock, MJ; Kaul, S; Mansuri, MM; Martin, JC; Sterzycki, RZ1
Lin, TS; Prusoff, WH; Schinazi, RF1
Balzarini, J; De Clercq, E; Herdewijn, P1
August, EM; Lin, TS; Marongiu, ME; Prusoff, WH1
Baba, M; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Vandeputte, M1
Hamamoto, Y; Matsuda, A; Matsui, T; Nakashima, H; Ueda, T; Yamamoto, N1

Reviews

5 review(s) available for stavudine and HIV

ArticleYear
Antiretrovirals for HIV Exposure Prophylaxis.
    Current medicinal chemistry, 2012, Volume: 19, Issue:35

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012
cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.
    Current topics in medicinal chemistry, 2002, Volume: 2, Issue:10

    Topics: Antiviral Agents; Benzyl Alcohols; Biotransformation; Dideoxynucleotides; HIV; Humans; Prodrugs; Stavudine; Structure-Activity Relationship; Thymine Nucleotides

2002
[Antiretroviral therapy. Current status and perspectives].
    Der Internist, 1994, Volume: 35, Issue:10

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Stavudine; Zalcitabine; Zidovudine

1994
Targeted therapy of human immunodeficiency virus-related disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1991
Comparative studies of 2',3'-didehydro-2',3'-dideoxythymidine (D4T) with other pyrimidine nucleoside analogues.
    Annals of the New York Academy of Sciences, 1990, Volume: 616

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Dideoxynucleosides; HIV; Humans; Stavudine

1990

Trials

23 trial(s) available for stavudine and HIV

ArticleYear
Long-term efficacy and safety of first-line therapy with once-daily saquinavir/ritonavir.
    Antiviral therapy, 2008, Volume: 13, Issue:3

    Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Combinations; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Hyperlipidemias; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Thailand; Time Factors; Treatment Outcome; Viral Load

2008
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
    Lancet (London, England), 2009, Dec-19, Volume: 374, Issue:9707

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine

2009
Pharmacokinetics of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian children.
    Antiviral therapy, 2010, Volume: 15, Issue:1

    Topics: Adolescent; Anti-HIV Agents; Body Weight; Child; Child, Preschool; Cross-Over Studies; Dosage Forms; Drug Administration Schedule; Drugs, Generic; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Malawi; Male; Nevirapine; Prospective Studies; Stavudine

2010
A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa.
    The Journal of infectious diseases, 2010, Nov-15, Volume: 202, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; RNA, Viral; South Africa; Stavudine; Treatment Outcome; Zidovudine

2010
Modulation of human immunodeficiency virus (HIV)-specific immune response by using efavirenz, nelfinavir, and stavudine in a rescue therapy regimen for HIV-infected, drug-experienced patients.
    Clinical and diagnostic laboratory immunology, 2002, Volume: 9, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4-Positive T-Lymphocytes; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interferon-gamma; Interleukin-10; Interleukin-2; Male; Nelfinavir; Oxazines; Random Allocation; RNA, Messenger; Stavudine; Treatment Failure

2002
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.
    Journal of acquired immune deficiency syndromes (1999), 2002, Dec-15, Volume: 31, Issue:5

    Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mutation; Patient Compliance; RNA, Viral; Stavudine; Viral Load; Zidovudine

2002
Results of a phase 2 clinical trial at 48 weeks (AI424-007): a dose-ranging, safety, and efficacy comparative trial of atazanavir at three doses in combination with didanosine and stavudine in antiretroviral-naive subjects.
    Journal of acquired immune deficiency syndromes (1999), 2003, Jan-01, Volume: 32, Issue:1

    Topics: Adult; Atazanavir Sulfate; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lipids; Nelfinavir; Oligopeptides; Pyridines; RNA, Viral; Stavudine; Time Factors; Viral Load

2003
Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Jan-15, Volume: 38, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Female; HIV; HIV Infections; HIV-1; Humans; Lipodystrophy; Male; Middle Aged; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2004
Pharmacokinetics and safety of stavudine in HIV-infected pregnant women and their infants: Pediatric AIDS Clinical Trials Group protocol 332.
    The Journal of infectious diseases, 2004, Dec-15, Volume: 190, Issue:12

    Topics: Adult; Amniotic Fluid; Anti-HIV Agents; Area Under Curve; Drug Therapy, Combination; Female; Half-Life; HIV; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Metabolic Clearance Rate; Pregnancy; Pregnancy Complications, Infectious; Stavudine; Viral Load

2004
Lowering the dose of hydroxyurea minimizes toxicity and maximizes anti-HIV potency.
    AIDS research and human retroviruses, 2005, Volume: 21, Issue:4

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Hydroxyurea; Male; RNA, Viral; Stavudine; Viral Load; Viremia

2005
Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program.
    Journal of acquired immune deficiency syndromes (1999), 2007, Mar-01, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV; HIV Infections; Humans; Lamivudine; Milk, Human; Nevirapine; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; RNA, Viral; Stavudine; Zidovudine

2007
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.
    Journal of acquired immune deficiency syndromes (1999), 2007, Aug-15, Volume: 45, Issue:5

    Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Composition; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Prospective Studies; Stavudine; Time Factors; Treatment Outcome; United States; Zidovudine

2007
The impact of reducing stavudine dose versus switching to tenofovir on plasma lipids, body composition and mitochondrial function in HIV-infected patients.
    Antiviral therapy, 2007, Volume: 12, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Body Composition; Cholesterol; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Lipodystrophy; Male; Middle Aged; Mitochondria; Organophosphonates; Oxygen Consumption; Stavudine; Tenofovir; Treatment Outcome; Triglycerides

2007
Dose-related activity of stavudine in patients infected with human immunodeficiency virus.
    The Journal of infectious diseases, 1995, Volume: 171 Suppl 2

    Topics: Adult; Aged; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; HIV; HIV Core Protein p24; HIV Infections; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Stavudine; Survival Analysis; Weight Gain

1995
An open randomized controlled trial of zidovudine plus lamivudine versus stavudine plus lamivudine.
    AIDS (London, England), 1998, Aug-20, Volume: 12, Issue:12

    Topics: Adult; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Homosexuality, Male; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

1998
Combination therapy with stavudine (d4T) plus didanosine (ddI) in children with human immunodeficiency virus infection. The Pediatric AIDS Clinical Trials Group 327 Team.
    Pediatrics, 1999, Volume: 103, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infant; Male; RNA, Viral; Statistics, Nonparametric; Stavudine

1999
Safety and antiretroviral effects of combined didanosine and stavudine therapy in HIV-infected individuals with CD4 counts of 200 to 500 cells/mm3.
    Journal of acquired immune deficiency syndromes (1999), 1999, Sep-01, Volume: 22, Issue:1

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; RNA, Viral; Stavudine; Viral Load; Virus Replication; Weight Gain

1999
In vivo antagonism with zidovudine plus stavudine combination therapy.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; RNA, Viral; Stavudine; Zidovudine

2000
The safety profile and antiviral activity of the combination of stavudine, didanosine, and nelfinavir in patients with HIV infection.
    Clinical therapeutics, 1999, Volume: 21, Issue:11

    Topics: Administration, Oral; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Nelfinavir; RNA, Viral; Safety; Stavudine; Treatment Outcome; Viral Load

1999
Efficacy, tolerance, and pharmacokinetics of the combination of stavudine, nevirapine, nelfinavir, and saquinavir as salvage regimen after ritonavir or indinavir failure.
    AIDS research and human retroviruses, 2001, Jan-20, Volume: 17, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Indinavir; Male; Middle Aged; Mutation; Nelfinavir; Nevirapine; Prospective Studies; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Treatment Failure; Viral Load

2001
Phase II/III Trials of Viracept start.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:3

    Topics: Anti-HIV Agents; Blood; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Pilot Projects; Reverse Transcriptase Inhibitors; Stavudine; Sulfonic Acids; Time Factors; Zidovudine

1996
Reappraising d4T.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:6

    Topics: CD4 Lymphocyte Count; HIV; HIV Infections; Humans; Randomized Controlled Trials as Topic; Stavudine; Zidovudine

1995
Addition of cyclophosphamide to antiretroviral therapy does not diminish the cellular reservoir in HIV-infected persons.
    AIDS research and human retroviruses, 2002, May-20, Volume: 18, Issue:8

    Topics: Adolescent; Adult; CD4 Lymphocyte Count; Cyclophosphamide; DNA, Viral; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lymphoid Tissue; Male; Middle Aged; Monocytes; Nelfinavir; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load

2002

Other Studies

93 other study(ies) available for stavudine and HIV

ArticleYear
Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Kinetics; Molecular Structure; Phosphorylation; Pyrimidine Nucleosides; Rabbits; Stavudine; T-Lymphocytes; Thymidine Kinase; Thymus Gland; Zidovudine

1990
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:6

    Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Molecular Conformation; X-Ray Diffraction

1990
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:2

    Topics: Antiviral Agents; Bone Marrow; Dideoxynucleosides; HIV; Stavudine; Thymidine; Zidovudine

1989
Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogues.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemical Phenomena; Chemistry; Deoxycytidine; HIV; Structure-Activity Relationship; T-Lymphocytes, Helper-Inducer; Zalcitabine

1987
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication

1987
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship

1987
Aryl phosphoramidate derivatives of d4T have improved anti-HIV efficacy in tissue culture and may act by the generation of a novel intracellular metabolite.
    Journal of medicinal chemistry, 1996, Apr-12, Volume: 39, Issue:8

    Topics: 3T3 Cells; Animals; Antiviral Agents; HIV; Mice; Phosphates; Stavudine; Structure-Activity Relationship

1996
Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Anti-HIV Agents; Cell Line; Dideoxynucleotides; Dose-Response Relationship, Drug; HeLa Cells; HIV; Humans; Phosphorylation; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Virus Replication; Zidovudine

2007
Liver steatosis and fibrosis in people with human immunodeficiency virus in West Africa and the relationship with hepatitis B virus coinfection.
    Hepatology communications, 2022, Volume: 6, Issue:11

    Topics: Adult; Coinfection; Fatty Liver; Female; Ghana; Hepatitis B; Hepatitis B virus; HIV; HIV Infections; Humans; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; RNA; Stavudine

2022
A retrospective case-cohort study comparing treatment outcomes in abacavir versus stavudine containing first line antiretroviral treatment regimens in children <3yrs old, at a paediatric programme based in Soweto, South Africa.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Child, Preschool; Dideoxynucleosides; Drug Combinations; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Lopinavir; Male; Retrospective Studies; Ritonavir; South Africa; Stavudine; Treatment Outcome; Viral Load

2017
Compromise of Second-Line Antiretroviral Therapy Due to High Rates of Human Immunodeficiency Virus Drug Resistance in Mozambican Treatment-Experienced Children With Virologic Failure.
    Journal of the Pediatric Infectious Diseases Society, 2020, Feb-28, Volume: 9, Issue:1

    Topics: Adolescent; Anti-Retroviral Agents; Child; Child, Preschool; Cross-Sectional Studies; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Mozambique; Nevirapine; Stavudine; Treatment Failure; Viral Load

2020
Adherence, virological outcome, and drug resistance in Chinese HIV patients receiving first-line antiretroviral therapy from 2011 to 2015.
    Medicine, 2018, Volume: 97, Issue:50

    Topics: Adult; Anti-HIV Agents; China; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Retrospective Studies; Stavudine; Sustained Virologic Response; Tenofovir; Zidovudine

2018
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
    Lipids in health and disease, 2013, Apr-10, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine

2013
Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Female; Health Resources; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Residence Characteristics; RNA, Viral; Stavudine; Tenofovir; Young Adult; Zidovudine

2013
Mitochondrial subhaplogroups and differential risk of stavudine-induced lipodystrophy in Malawian HIV/AIDS patients.
    Pharmacogenomics, 2013, Volume: 14, Issue:16

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; DNA, Mitochondrial; Female; Genetic Predisposition to Disease; Haplotypes; HIV; HIV Infections; Humans; Lipodystrophy; Male; Middle Aged; Mitochondria; Stavudine

2013
Estimation of intracellular concentration of stavudine triphosphate in HIV-infected children given a reduced dose of 0.5 milligrams per kilogram twice daily.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2

    Topics: Adult; Anti-HIV Agents; Child; Drug Administration Schedule; Drug Dosage Calculations; Female; HIV; HIV Infections; Humans; Male; Mitochondria; Models, Statistical; Stavudine

2014
Virologic response in children treated with abacavir-compared with stavudine-based antiretroviral treatment: a South African multi-cohort analysis.
    The Pediatric infectious disease journal, 2014, Volume: 33, Issue:6

    Topics: Adolescent; Anti-HIV Agents; Child; Cohort Studies; Dideoxynucleosides; Female; HIV; HIV Infections; Humans; Male; South Africa; Stavudine; Treatment Outcome; Viral Load

2014
MicroRNA-150 is a potential biomarker of HIV/AIDS disease progression and therapy.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Drug Resistance, Viral; Female; Gene Expression Regulation; HIV; Humans; Lamivudine; Leukocytes, Mononuclear; Male; MicroRNAs; Nevirapine; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2014
Trends in first-line antiretroviral therapy in Asia: results from the TREAT Asia HIV observational database.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Asia; Dideoxynucleosides; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine

2014
Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania.
    International journal of dermatology, 2015, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Prospective Studies; RNA, Viral; Severity of Illness Index; Skin Diseases; Stavudine; Tanzania; Young Adult

2015
Implementation of isoniazid preventive therapy in an HIV clinic in Cambodia: high rates of discontinuation when combined with antiretroviral therapy.
    Tropical medicine & international health : TM & IH, 2015, Volume: 20, Issue:12

    Topics: Adult; Ambulatory Care Facilities; Anti-HIV Agents; Antitubercular Agents; Cambodia; Drug Interactions; Female; HIV; HIV Infections; Humans; Isoniazid; Lamivudine; Male; Nevirapine; Opportunistic Infections; Patient Dropouts; Retrospective Studies; Stavudine; Tuberculosis

2015
Plasma Mitochondrial DNA Levels as a Biomarker of Lipodystrophy Among HIV-infected Patients Treated with Highly Active Antiretroviral Therapy (HAART).
    Current molecular medicine, 2015, Volume: 15, Issue:10

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; Case-Control Studies; Cyclopropanes; DNA, Mitochondrial; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Lopinavir; Male; Middle Aged; Mitochondria; Nelfinavir; Predictive Value of Tests; Ritonavir; ROC Curve; Stavudine; Zidovudine

2015
HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia.
    Antiviral therapy, 2017, Volume: 22, Issue:2

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Coinfection; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; Ethiopia; Female; Genetic Variation; Genome, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Immune Evasion; Lamivudine; Male; Mutation; Stavudine; Viral Load; Zidovudine

2017
First-line antiretroviral drug discontinuations in children.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Follow-Up Studies; HIV; HIV Infections; Humans; Infant; Kaplan-Meier Estimate; Lopinavir; Outcome Assessment, Health Care; Proportional Hazards Models; Ritonavir; South Africa; Stavudine; Withholding Treatment; Zidovudine

2017
Synthesis of nucleoside-based antiviral drugs in ionic liquids.
    Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20

    Topics: Antiviral Agents; Bromodeoxyuridine; Chemistry, Pharmaceutical; Drug Design; HIV; Humans; Imidazoles; Ionic Liquids; Models, Chemical; Nucleosides; Simplexvirus; Solubility; Solvents; Stavudine; Trifluridine

2008
Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings.
    The Journal of infectious diseases, 2009, Sep-01, Volume: 200, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Stavudine; Young Adult; Zidovudine

2009
A longitudinal study of the changes in body fat and metabolic parameters in a South African population of HIV-positive patients receiving an antiretroviral therapeutic regimen containing stavudine.
    AIDS research and human retroviruses, 2009, Volume: 25, Issue:8

    Topics: Adipose Tissue; Adult; Anti-Retroviral Agents; Female; HIV; HIV Infections; Humans; Insulin; Lipids; Lipodystrophy; Longitudinal Studies; Male; Middle Aged; Risk Factors; South Africa; Stavudine

2009
Tumour necrosis factor haplotypes associated with sensory neuropathy in Asian and Caucasian human immunodeficiency virus patients.
    Tissue antigens, 2011, Volume: 77, Issue:2

    Topics: Anthropometry; Anti-HIV Agents; Asian People; Body Height; Genotype; Haplotypes; HIV; HIV Infections; Humans; Peripheral Nervous System Diseases; Polymerase Chain Reaction; Polymorphism, Genetic; Risk Assessment; Risk Factors; Stavudine; Tumor Necrosis Factors; White People

2011
Evaluating patients for second-line antiretroviral therapy in India: the role of targeted viral load testing.
    Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine

2010
Reduced dose of stavudine and lipoatrophy in HIV-infected patients in Cameroon.
    Antiviral therapy, 2010, Volume: 15, Issue:7

    Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Male; Middle Aged; Nevirapine; Stavudine; Zidovudine

2010
Self-reported adherence to HAART in South-Eastern Nigeria is related to patients' use of pill box.
    SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance, 2010, Volume: 7, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Algorithms; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Feasibility Studies; Female; HIV; HIV Infections; Humans; Lamivudine; Linear Models; Male; Medication Adherence; Middle Aged; Nevirapine; Nigeria; Patient Satisfaction; Prospective Studies; Reminder Systems; Risk Factors; Self Report; Stavudine; Surveys and Questionnaires; Treatment Outcome

2010
Stavudine entrapped lipid nanoparticles for targeting lymphatic HIV reservoirs.
    Die Pharmazie, 2011, Volume: 66, Issue:4

    Topics: Animals; Anti-HIV Agents; Calorimetry, Differential Scanning; Cell Survival; Coloring Agents; Drug Compounding; Electrochemistry; Fluorescent Dyes; HIV; HIV Seropositivity; In Vitro Techniques; Lymphatic System; Macrophages; Male; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Particle Size; Rats; Rats, Wistar; Rhodamine 123; Stavudine; Tetrazolium Salts; Thiazoles; Tissue Distribution

2011
Methylmethacrylate-sulfopropylmethacrylate nanoparticles with surface RMP-7 for targeting delivery of antiretroviral drugs across the blood-brain barrier.
    Colloids and surfaces. B, Biointerfaces, 2012, Feb-01, Volume: 90

    Topics: Ammonium Sulfate; Anti-HIV Agents; Astrocytes; Biological Transport; Blood-Brain Barrier; Bradykinin; Cells, Cultured; Coculture Techniques; Delavirdine; Drug Carriers; Endothelial Cells; HIV; HIV Infections; Humans; Kinetics; Methacrylates; Microscopy, Electron, Scanning; Molecular Targeted Therapy; Nanoparticles; Particle Size; Permeability; Saquinavir; Stavudine

2012
Effectiveness and safety of 30 mg versus 40 mg stavudine regimens: a cohort study among HIV-infected adults initiating HAART in South Africa.
    Journal of the International AIDS Society, 2012, Mar-12, Volume: 15, Issue:1

    Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cohort Studies; Dose-Response Relationship, Drug; Female; HIV; HIV Infections; Humans; Male; Prospective Studies; South Africa; Stavudine

2012
Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine.
    Antiviral therapy, 2002, Volume: 7, Issue:2

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV; Humans; Phosphorylation; RNA, Messenger; Stavudine; T-Lymphocytes; Thymidine Kinase; Time Factors; Zidovudine

2002
Rheumatoid arthritis after 9 years of human immunodeficiency virus infection: possible contribution of tritherapy.
    The Journal of rheumatology, 2002, Volume: 29, Issue:10

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Arthritis, Reactive; HIV; HIV Infections; Humans; Immunocompromised Host; Lamivudine; Male; Saquinavir; Stavudine; Treatment Outcome

2002
Effects of aryl substituents on the anti-HIV activity of the arylphosphoramidate derivatives of stavudine.
    Antiviral chemistry & chemotherapy, 2002, Volume: 13, Issue:3

    Topics: Anti-HIV Agents; Cells, Cultured; HIV; Humans; Hydrogen-Ion Concentration; Hydrolysis; Leukocytes, Mononuclear; Molecular Structure; Stavudine; Virus Replication

2002
Risk factors for lactic acidosis in HIV-infected patients treated with nucleoside reverse-transcriptase inhibitors: a case-control study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, May-15, Volume: 36, Issue:10

    Topics: Acidosis, Lactic; Adult; Case-Control Studies; Didanosine; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine

2003
Development and evaluation of a thermoreversible ovule formulation of stampidine, a novel nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide.
    Biology of reproduction, 2003, Volume: 69, Issue:6

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Dideoxynucleotides; Drug Compounding; Drug Evaluation, Preclinical; Drug Stability; Female; HIV; Hydrogen-Ion Concentration; Hyperplasia; Kinetics; Rabbits; Solubility; Spermatocidal Agents; Stavudine; Thymidine Monophosphate; Vagina; Vaginitis

2003
In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Cells, Cultured; Dideoxynucleotides; Drug Resistance, Viral; Genotype; HIV; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Neutrophils; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate; Viral Plaque Assay; Zidovudine

2004
Can the peripheral blood monocyte count be used as a marker of CSF resistance to antiretroviral drugs?
    Journal of neurovirology, 2004, Volume: 10 Suppl 1

    Topics: Anti-HIV Agents; Biomarkers; Buffers; Culture Media; Dideoxynucleosides; Drug Resistance, Viral; HIV; HIV Infections; Humans; In Vitro Techniques; Leukocyte Count; Monocytes; Stavudine; Zidovudine

2004
Stampidine is a potential nonspermicidal broad-spectrum anti-human immunodeficiency virus microbicide.
    Fertility and sterility, 2004, Volume: 81 Suppl 1

    Topics: Animals; Anti-HIV Agents; Biomechanical Phenomena; Cattle; Cervix Mucus; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Stability; Female; Fertility; Gels; HIV; Humans; Hydrogen-Ion Concentration; Male; Mucous Membrane; Pregnancy; Rabbits; Sperm Motility; Spermatozoa; Stavudine; Thymidine Monophosphate; Vagina

2004
Bis-ketol nucleoside triesters as prodrugs of the antiviral nucleoside triphosphate analogues of 3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:3

    Topics: Anti-HIV Agents; Cell Line; Esters; HIV; Humans; Molecular Structure; Nucleosides; Prodrugs; Stavudine; Thymidine

2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
    AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12

    Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2004
Simultaneous determination of the HIV nucleoside analogue reverse transcriptase inhibitors lamivudine, didanosine, stavudine, zidovudine and abacavir in human plasma by reversed phase high performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Feb-25, Volume: 816, Issue:1-2

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Drug Stability; HIV; HIV Infections; Humans; Lamivudine; Quality Control; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine

2005
Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine.
    The Journal of infectious diseases, 2005, Apr-01, Volume: 191, Issue:7

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; DNA, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Oxazines; RNA, Viral; Stavudine; Tenofovir; Viremia

2005
A new approach to the synthesis of 4'-carbon-substituted nucleosides: development of a highly active anti-HIV agent 2', 3'-didehydro-3'-deoxy-4'-ethynylthymidine.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Anti-HIV Agents; Carbon; Cell Line; HIV; Humans; Inhibitory Concentration 50; Models, Chemical; Nucleosides; Oxygen; Stavudine

2005
Homo and heterodimers of ddI, d4T and AZT: influence of (5'-5') thiolcabonate-carbamate linkage on anti-HIV activity.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Anti-HIV Agents; Antiviral Agents; Carbamates; Didanosine; Dimerization; HIV; HIV Infections; Models, Chemical; Molecular Conformation; Mutation; Stavudine; Sulfhydryl Compounds; Zidovudine

2005
"Lock-in" modified cyclosal nucleotides--the second generation of cyclosal prodrugs.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Anti-HIV Agents; Binding Sites; Cell Line; Chemistry, Pharmaceutical; Dideoxynucleotides; Drug Design; Esterases; HIV; HIV Infections; Humans; Hydrolysis; Models, Chemical; Mutation; Nucleotides; Prodrugs; Protein Isoforms; Stavudine; Thymine Nucleotides

2005
Synthesis, separation and anti-HIV activity of distereoisomers of N-[p-(4-bromophenyl) -2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine methyl ester (stampidine).
    Arzneimittel-Forschung, 2006, Volume: 56, Issue:2A

    Topics: Anti-HIV Agents; Chemical Phenomena; Chemistry, Physical; Crystallization; Dideoxynucleotides; HIV; HIV-1; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Monocytes; Stavudine; Stereoisomerism; Structure-Activity Relationship; Thymidine Monophosphate

2006
Thyroid function in human immunodeficiency virus patients treated with highly active antiretroviral therapy (HAART): a longitudinal study.
    Clinical endocrinology, 2006, Volume: 64, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Autoantibodies; CD4 Lymphocyte Count; Epidemiologic Methods; Female; HIV; HIV Infections; Humans; Iodide Peroxidase; Male; Middle Aged; Stavudine; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine

2006
Insights on resistance to reverse transcriptase: the different patterns of interaction of the nucleoside reverse transcriptase inhibitors in the deoxyribonucleotide triphosphate binding site relative to the normal substrate.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Binding Sites; Computer Simulation; Deoxyribonucleotides; Drug Resistance, Multiple, Viral; HIV; HIV Reverse Transcriptase; Humans; Molecular Conformation; Nucleosides; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zalcitabine

2006
Association between hepatitis C virus coinfection and regional adipose tissue volume in HIV-infected men and women.
    Journal of acquired immune deficiency syndromes (1999), 2007, May-01, Volume: 45, Issue:1

    Topics: Adipose Tissue; Adult; Anti-HIV Agents; Body Fat Distribution; Cohort Studies; Cross-Sectional Studies; Female; Hepatitis C; HIV; HIV Infections; Humans; Lipodystrophy; Magnetic Resonance Imaging; Male; Middle Aged; Multivariate Analysis; Prevalence; RNA, Viral; Stavudine; Subcutaneous Fat

2007
Anti-retroviral activity of GMP-grade stampidine against genotypically and phenotypically nucleoside reverse transcriptase inhibitor resistant recombinant human immunodeficiency virus. An in vitro study.
    Arzneimittel-Forschung, 2007, Volume: 57, Issue:2

    Topics: Anti-HIV Agents; Capsules; Chemistry, Pharmaceutical; Cloning, Molecular; Cytopathogenic Effect, Viral; Dideoxynucleotides; Drug Resistance, Viral; HIV; HIV-1; Humans; Mutation; Regression Analysis; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate

2007
Decreasing CD4+ T-cell count during suppressed or low-level viraemia in patients with HIV infection.
    Antiviral therapy, 2007, Volume: 12, Issue:7

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Female; HIV; HIV Infections; Humans; Male; RNA, Viral; Stavudine; Viral Load; Viremia; Zidovudine

2007
Synthesis and anti-HIV evaluation of hybrid-type prodrugs conjugating HIV integrase inhibitors with d4t by self-cleavable spacers containing an amino acid residue.
    Journal of enzyme inhibition and medicinal chemistry, 2007, Volume: 22, Issue:5

    Topics: Alanine; Anti-HIV Agents; Cells, Cultured; Dimerization; HIV; HIV Integrase Inhibitors; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Prodrugs; Reverse Transcriptase Inhibitors; Stavudine

2007
The role of antiretroviral therapy in the incidence of pancreatitis in HIV-positive individuals in the EuroSIDA study.
    AIDS (London, England), 2008, Jan-02, Volume: 22, Issue:1

    Topics: Adult; Anti-Retroviral Agents; Argentina; Case-Control Studies; CD4-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Europe; Female; HIV; HIV Infections; Humans; Incidence; Israel; Lymphopenia; Male; Middle Aged; Pancreatitis; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine

2008
[Anti-HIV drug development: future prospect and problems].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Antiviral Agents; Carrier State; CD4 Antigens; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Oligonucleotides, Antisense; Reverse Transcriptase Inhibitors; Stavudine

1993
Evaluation of the combination effect of different antiviral compounds against HIV in vitro.
    Scandinavian journal of infectious diseases, 1993, Volume: 25, Issue:3

    Topics: Antiviral Agents; Benzodiazepines; Didanosine; Dideoxynucleosides; Drug Combinations; Drug Evaluation; Drug Synergism; HIV; Humans; Imidazoles; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

1993
Effect of 2',3'-didehydro-3'-deoxythymidine in an in vitro hollow-fiber pharmacodynamic model system correlates with results of dose-ranging clinical studies.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:6

    Topics: Cell Line; DNA, Viral; Dose-Response Relationship, Drug; HIV; Humans; Models, Biological; Stavudine; Virus Replication

1994
Comparative embryonic cytotoxicity of antiretroviral nucleosides.
    The Journal of infectious diseases, 1994, Volume: 169, Issue:5

    Topics: Animals; Antiviral Agents; Culture Techniques; Didanosine; Embryo, Mammalian; HIV; Mice; Nucleosides; Stavudine; Zalcitabine; Zidovudine

1994
Prodrugs of 2',3'-didehydro-3'-deoxythymidine (D4T): synthesis, antiviral activity, and rapid pharmacokinetic evaluation.
    Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:3

    Topics: Animals; Antiviral Agents; Biological Availability; Chemical Phenomena; Chemistry, Physical; HIV; Leukemia Virus, Murine; Mice; Prodrugs; Stavudine

1994
In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9

    Topics: Aminoisobutyric Acids; Animals; Antiviral Agents; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Feces; HIV; In Vitro Techniques; Injections, Intravenous; Injections, Subcutaneous; Liver; Macaca fascicularis; Macaca mulatta; Rats; Rats, Sprague-Dawley; Stavudine; Thymine; Zidovudine

1993
Pharmacokinetics of the anti-human immunodeficiency virus nucleoside analog stavudine in cynomolgus monkeys.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:5

    Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Dideoxynucleosides; Half-Life; HIV; Humans; Macaca fascicularis; Male; Random Allocation; Stavudine

1993
2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.
    Molecular pharmacology, 1996, Volume: 50, Issue:1

    Topics: Amides; Biotransformation; Biphenyl Compounds; Cell Line; Deoxyguanosine; Floxuridine; HIV; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Kinetics; Methotrexate; Models, Biological; Phosphorylation; Pyrazoles; Reverse Transcriptase Inhibitors; Ribonucleosides; Ribose; RNA-Directed DNA Polymerase; Stavudine; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured

1996
Therapy of HIV infections: problems and prospects.
    Bulletin of the New York Academy of Medicine, 1996,Summer, Volume: 73, Issue:1

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Stavudine; Urban Health; Zalcitabine; Zidovudine

1996
Phenotypic variations and switches in HIV isolated from the blood and the gastrointestinal tissues of patients with HIV-1 infection. HIV/GI Research Study Group.
    Journal of medical virology, 1997, Volume: 52, Issue:1

    Topics: Biopsy; Didanosine; Digestive System; Female; Giant Cells; HIV; HIV Enteropathy; HIV Infections; Humans; Male; Mutation; Phenotype; Prospective Studies; Stavudine; Viral Load; Zidovudine

1997
Cure or control of HIV/AIDS?
    Medical hypotheses, 1997, Volume: 48, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1997
Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation.
    Antiviral research, 1997, Volume: 35, Issue:3

    Topics: Amides; Amino Acids; Animals; Cell Line; HIV; HIV-1; HIV-2; Humans; Mice; Organophosphates; Organophosphorus Compounds; Phosphoric Acids; Stavudine; Structure-Activity Relationship; Thymidine Kinase

1997
Antiretroviral triple therapy decreases HIV viral load but does not alter hepatitis C virus (HCV) serum levels in HIV-HCV-co-infected haemophiliacs.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Hemophilia A; Hepacivirus; Hepatitis C; HIV; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zidovudine

1998
Gynecomastia with stavudine treatment in an HIV-positive patient.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:10

    Topics: Adult; Anti-HIV Agents; Gynecomastia; HIV; HIV Seropositivity; Humans; Male; Stavudine

1998
Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
    Molecular pharmacology, 1999, Volume: 56, Issue:4

    Topics: Amino Acids; Animals; Anti-HIV Agents; Biotransformation; Dideoxynucleotides; Drug Design; Esterases; Esters; HIV; Humans; Liver; Male; Mice; Nucleosides; Prodrugs; Rats; Rats, Wistar; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Tumor Cells, Cultured; Zidovudine

1999
Use of recombinant viruses to assess the pattern of early human immunodeficiency virus breakthrough infection in the presence of stavudine.
    The Journal of general virology, 1999, Volume: 80 ( Pt 9)

    Topics: Animals; Anti-HIV Agents; COS Cells; Defective Viruses; Floxuridine; HeLa Cells; HIV; Humans; Jurkat Cells; Leukemia Virus, Murine; Recombination, Genetic; Stavudine; Zidovudine

1999
Emergence of zidovudine resistance in HIV-infected patients receiving stavudine.
    Journal of acquired immune deficiency syndromes (1999), 2000, Mar-01, Volume: 23, Issue:3

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Stavudine; Zidovudine

2000
Cutaneous side effects induced by indinavir.
    European journal of dermatology : EJD, 2000, Volume: 10, Issue:4

    Topics: Adult; Alopecia; Didanosine; Drug Eruptions; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Middle Aged; Pruritus; Pyoderma Gangrenosum; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Scalp Dermatoses; Skin; Stavudine; Zalcitabine; Zidovudine

2000
Adherence, side effects and efficacy of stavudine plus lamivudine plus nelfinavir in treatment-experienced HIV-infected patients.
    The Journal of infection, 2000, Volume: 41, Issue:1

    Topics: Adult; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Female; Hepatitis C; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Logistic Models; Male; Nelfinavir; Patient Compliance; Polymerase Chain Reaction; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Statistics, Nonparametric; Stavudine; Substance Abuse, Intravenous

2000
Gene mutations identified.
    AIDS patient care and STDs, 2001, Volume: 15, Issue:1

    Topics: Anti-HIV Agents; Computer Simulation; HIV; Humans; Models, Genetic; Mutation; Stavudine

2001
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James.
    AIDS treatment news, 1995, Aug-04, Issue:no 228

    Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1995
Protease inhibitor trials moving to next phase.
    AIDS alert, 1995, Volume: 10, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Nelfinavir; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication

1995
Nipping HIV in the bud.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine

1996
ddI plus d4T.
    AIDS treatment news, 1996, Sep-06, Issue:No 254

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Stavudine

1996
Hydroxyurea - new observations.
    Project Inform perspective, 1998, Issue:24

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Indinavir; Nucleic Acid Synthesis Inhibitors; Stavudine; Viral Load; Virus Replication

1998
Stavudine (Zerit).
    Research initiative, treatment action : RITA, 2000, Volume: 6, Issue:1

    Topics: Drug Resistance, Microbial; HIV; HIV Infections; Humans; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Stavudine

2000
An APE that proofreads.
    Nature, 2002, Feb-07, Volume: 415, Issue:6872

    Topics: Anti-HIV Agents; Carbon-Oxygen Lyases; DNA; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Viral; Escherichia coli; HIV; Humans; Stavudine; Substrate Specificity; Zidovudine

2002
Substrate specificity of Escherichia coli thymidine phosphorylase for pyrimidine nucleosides with anti-human immunodeficiency virus activity.
    Biochemical pharmacology, 1992, Jul-22, Volume: 44, Issue:2

    Topics: Antiviral Agents; Biological Availability; Deoxyuridine; Dideoxynucleosides; Emtricitabine; Escherichia coli; HIV; Pyrimidine Nucleosides; Stavudine; Substrate Specificity; Thymidine Phosphorylase; Zalcitabine

1992
High-performance liquid chromatographic determination of 2',3'-didehydro-3'-deoxythymidine, a new anti-human immunodeficiency virus agent, in human plasma and urine.
    Journal of chromatography, 1992, May-20, Volume: 577, Issue:1

    Topics: Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Humans; Male; Reproducibility of Results; Spectrophotometry, Ultraviolet; Stavudine

1992
Structural studies of the anti-HIV agent 2',3'-didehydro-2',3'-dideoxythymidine (D4T).
    Biochemical and biophysical research communications, 1991, Feb-28, Volume: 175, Issue:1

    Topics: Antiviral Agents; Dideoxynucleosides; HIV; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Structure; Stavudine

1991
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
    Molecular pharmacology, 1991, Volume: 39, Issue:5

    Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine

1991
Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus.
    Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17

    Topics: Antiviral Agents; Deoxycytidine; HIV; Humans; Monocytes; Retroviridae Proteins; RNA-Directed DNA Polymerase; Stavudine; Thymidine; Virus Replication; Zidovudine

1987
Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.
    The Journal of biological chemistry, 1989, Apr-15, Volume: 264, Issue:11

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Deoxyribonucleotides; Dideoxynucleosides; Dose-Response Relationship, Drug; HIV; Humans; Mice; Phosphorylation; Sarcoma Viruses, Murine; Solubility; Stavudine; Thymidine; Zidovudine

1989
Initial studies on the cellular pharmacology of 3'-deoxythymidin-2'-ene (d4T): a potent and selective inhibitor of human immunodeficiency virus.
    Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23

    Topics: Cell Division; Cell Line; Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV; Humans; Stavudine; Virus Replication

1988
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
    Biochemical and biophysical research communications, 1987, Jan-15, Volume: 142, Issue:1

    Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Structure-Activity Relationship; Thymidine; Virus Replication; Zidovudine

1987
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6

    Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Stavudine; Thymidine; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1987