Compounds > stavudine
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stavudine and Adverse Drug Event

stavudine has been researched along with Adverse Drug Event in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's13 (76.47)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Boulle, A; Cohen, K; Davies, MA; de Waal, R; Fox, MP; Igumbor, EU; Maartens, G1
Lungu, M; Mathews, T; Tapsfield, J; van Oosterhout, JJ1
Chagoma, N; Heyderman, RS; Kampira, E; Kaunda, S; Mallewa, J; Mukaka, M; Njalale, Y; van Oosterhout, JJ1
Boettiger, DC; Chaiwarith, R; Choi, JY; Ditangco, R; Kamarulzaman, A; Kantipong, P; Kerr, S; Kiertiburanakul, S; Kumarasamy, N; Law, M; Lee, C; Li, CK; Merati, TP; Mustafa, M; Ng, OT; Oka, S; Pham, TT; Pujari, S; Ratanasuwan, W; Sohn, A; Van Kinh, N; Vonthanak, S; Wong, WW; Yunihastuti, E; Zhang, F1
Havens, PL; Hazra, R1
Arterburn, S; Castaño, E; Cheng, AK; Chuck, SL; Church, J; Deville, J; Enejosa, JV; Estripeaut, D; Gaur, A; Rathore, M; Rhee, MS; Saez-Llorens, X; White, K1
Barnett, BS; Chaweza, T; Hosseinipour, MC; Ngambi, W; Phiri, S; Tweya, H1
Agu, KA; Akpoigbe, KJ; Badru, T; Chabikuli, O; Eluwa, GI; Hamelmann, C1
Chersich, M; Fairlie, L; Kuhn, L; Meyers, T; Moultrie, H; Palmer, M1
Rastegar, DA1
Asmuth, D; Bakare, N; Blick, G; Farthing, C; Foli, A; Frank, I; Greiger, P; Groff, A; Herman, D; Lisziewicz, J; Lori, F; Lova, L; Norris, D; Peterson, D; Pollard, RB; Rashbaum, B; Schrader, S; Shalit, P; Tennenberg, A; Whitman, L1
Samuels, DC1

Reviews

1 review(s) available for stavudine and Adverse Drug Event

ArticleYear
Computational models of antiviral toxicity.
    Current opinion in drug discovery & development, 2007, Volume: 10, Issue:1

    Topics: Anti-HIV Agents; Computer Simulation; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Lamivudine; Molecular Structure; Stavudine; Zidovudine

2007

Trials

2 trial(s) available for stavudine and Adverse Drug Event

ArticleYear
A randomized, open-label study of the safety and efficacy of switching stavudine or zidovudine to tenofovir disoproxil fumarate in HIV-1-infected children with virologic suppression.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; RNA, Viral; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2015
Lowering the dose of hydroxyurea minimizes toxicity and maximizes anti-HIV potency.
    AIDS research and human retroviruses, 2005, Volume: 21, Issue:4

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Hydroxyurea; Male; RNA, Viral; Stavudine; Viral Load; Viremia

2005

Other Studies

14 other study(ies) available for stavudine and Adverse Drug Event

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Routine data underestimates the incidence of first-line antiretroviral drug discontinuations due to adverse drug reactions: Observational study in two South African cohorts.
    PloS one, 2018, Volume: 13, Issue:9

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Kaplan-Meier Estimate; Retrospective Studies; South Africa; Stavudine; Tenofovir

2018
Underreporting of side effects of standard first-line ART in the routine setting in Blantyre, Malawi.
    Malawi medical journal : the journal of Medical Association of Malawi, 2011, Volume: 23, Issue:4

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Ambulatory Care Facilities; Anti-HIV Agents; Cross-Sectional Studies; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Interviews as Topic; Lamivudine; Lipodystrophy; Malawi; Male; Middle Aged; Nevirapine; Peripheral Nervous System Diseases; Prevalence; Stavudine; Surveys and Questionnaires; Urban Population

2011
Longitudinal lactate levels from routine point-of-care monitoring in adult Malawian antiretroviral therapy patients: associations with stavudine toxicities.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2013, Volume: 107, Issue:10

    Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Drug Costs; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lactic Acid; Lipodystrophy; Malawi; Male; Medically Underserved Area; Peripheral Nervous System Diseases; Point-of-Care Systems; Prospective Studies; Stavudine

2013
Trends in first-line antiretroviral therapy in Asia: results from the TREAT Asia HIV observational database.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Asia; Dideoxynucleosides; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Male; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine

2014
Commentary: The place of tenofovir disoproxil fumarate in pediatric antiretroviral therapy.
    The Pediatric infectious disease journal, 2015, Volume: 34, Issue:4

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Stavudine; Zidovudine

2015
Assessment of non-standard HIV antiretroviral therapy regimens at Lighthouse Trust in Lilongwe, Malawi.
    Malawi medical journal : the journal of Medical Association of Malawi, 2016, Volume: 28, Issue:1

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cross-Sectional Studies; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Lamivudine; Malawi; Male; Nevirapine; Stavudine; Treatment Outcome; Trust; Young Adult

2016
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
    BMC clinical pharmacology, 2012, Feb-27, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine

2012
Frequency of stavudine substitution due to toxicity in children receiving antiretroviral treatment in sub-Saharan Africa.
    AIDS (London, England), 2013, Mar-13, Volume: 27, Issue:5

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Retrospective Studies; Risk Factors; South Africa; Stavudine; Time Factors

2013
Mitochondrial DNA and nucleoside toxicity.
    The New England journal of medicine, 2002, Jul-18, Volume: 347, Issue:3

    Topics: Anti-HIV Agents; DNA; DNA, Mitochondrial; Drug-Related Side Effects and Adverse Reactions; Genetic Markers; HIV Infections; Humans; Lactic Acid; Stavudine

2002