staurosporine has been researched along with Pregnancy in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 26 (42.62) | 18.2507 |
| 2000's | 26 (42.62) | 29.6817 |
| 2010's | 7 (11.48) | 24.3611 |
| 2020's | 2 (3.28) | 2.80 |
| Authors | Studies |
|---|---|
| Ojha, S; Ooi, MG | 1 |
| Arvanitis, D; Arvanitis, N; Chalatsa, I; Frakolaki, E; Kalantzis, ED; Sideris, DC; Tsakou, AC; Vassilacopoulou, D; Vassilaki, N; Vassiliou, AG | 1 |
| Becker, JC; Carney, RP; Farmer, DL; Gao, K; Herout, K; Keller, BA; Kumar, P; Lam, KS; Lankford, L; Wang, A | 1 |
| Sitarz, AM; Szychowski, KA; Wojtowicz, AK | 1 |
| Balachandran, S; Henkins, KM; Kulkarni, A; Matullo, CM; O'Donnell, LA; Pattisapu, AK; Rall, GF | 1 |
| Akanda, N; Brask, J; Ceccatelli, S; Elinder, F; Tamm, C; Tofighi, R | 1 |
| Budziszewska, B; Jantas, D; Lason, W; Szymanska, M | 1 |
| Jantas, D; Jaworska-Feil, L; Lason, W; Lipkowski, AW | 1 |
| Chen, B; Longtine, MS; Nelson, DM; Sadovsky, Y | 1 |
| Boyd, JD; Crosby, G; Culley, DJ; Kojima, K; Palanisamy, A; Tanzi, RE; Vacanti, CA; Xie, Z | 1 |
| Hills, FA; Mehmet, H; Sullivan, MH | 1 |
| Ford, AL; Gonzales, E; Holtzman, DM; Lee, JM; Lee, KY; West, T; Xiao, Q; Xu, J; Yan, P | 1 |
| Tang, XC; Zhang, HY | 1 |
| Cornel, L; Little, SA; Mirkes, PE; Soleman, D | 1 |
| Dave, JR; Koenig, ML; Moffett, JR; Tortella, FC; Williams, AJ | 1 |
| Baran, V; Fabian, D; Koppel, J; Rehak, P | 1 |
| Christen, Y; Massieu, L; Morán, J | 1 |
| Iadecola, C; Qian, L; Zhou, P | 1 |
| Bryant-Greenwood, G; Büllesbach, E; Kawamata, T; Millar, L; Okabe, R; Schwabe, C; Shimoda, J; Streiner, N; Webster, L; Yamamoto, S | 1 |
| Morisaki, T; Sakamaki, K; Toyokuni, S; Yajima, N; Yamada, S; Yonehara, S | 1 |
| Akhtar, RS; Carroll, SL; Geng, Y; Klocke, BJ; Latham, CB; Michalak, EM; Roth, KA; Strasser, A; Villunger, A | 1 |
| Beyer, C; Kajta, M; Lasoń, W; Trotter, A | 1 |
| Hermann, K; Kausler, S; Knerr, I; Lehner, M; Meissner, U; Rascher, W; Schnare, M; Vogler, T | 1 |
| Damdimopoulos, AE; Huhtaniemi, I; Jalkanen, J; Poutanen, M; Pujianto, DA; Sipilä, P | 1 |
| Choi, BH; Choi, JK; Ha, Y; Park, H; Park, HC; Park, SR; Yoon, SH | 1 |
| Abe, T; Aoki, S; Ayukawa, K; Hara, Y; Kudo, Y; Nishikawa, K; Nishimoto, M; Ohashi, H; Wada, K | 1 |
| Li, CG; Xue, CC; Yu, XQ; Zhou, SF; Zhou, ZW | 1 |
| Cole, OF; Elder, MG; Seki, H; Sullivan, MH | 1 |
| Bitrick, MS; Smith, TL | 1 |
| He, H; Herington, AC; Roupas, P | 1 |
| Catravas, JD; Ganapathy, V; Leibach, FH; Papapetropoulos, A; Ramamoorthy, JD; Ramamoorthy, S | 1 |
| Gurevich, M; Harel-Markowitz, E; Shemesh, M; Shore, LS | 1 |
| Fabbro, D; Hynes, NE; Jaken, S; Marte, BM; Meyer, T; Stabel, S; Standke, GJ | 1 |
| Adamson, S; Coulam, C; Edwin, SS; LaMarche, S; Mitchell, MD; Silver, RM | 1 |
| Mitchell, MD; Pollard, JK | 1 |
| Boneh, A; Brenner, T; Shohami, E | 1 |
| Bayat-Sarmadi, M; Houdebine, LM | 1 |
| Ahmed, A; Dearn, SR; Morrison, JJ; Smith, SK | 1 |
| Carson, DD; Ding, ZM; Kuo, MT; Wegner, CC; Zhou, X | 1 |
| Chakravarthy, B; Durkin, JP; Mealing, G; Morley, P; Small, D; Song, D; Tremblay, R | 1 |
| Galindo, MF; Jordán, J; Miller, RJ | 1 |
| O'Neill, C | 1 |
| Kandaswamy, V; Sen, S; Sil, P | 1 |
| Brennand, JE; Calder, AA; Greer, IA; Kelly, RW; Leask, R | 1 |
| Buyon, JP; Casiano, CA; Chan, EK; Di Donato, F; Miranda, ME; Ochs, RL; Rashbaum, W; Tseng, CE | 1 |
| Durkin, JP; Hewitt, K; Lesiuk, H; Mealing, G; Morley, P; Tremblay, R | 1 |
| Alexander, BT; Granger, JP; Kanashiro, CA; Khalil, RA | 1 |
| Hilliard, A; Ramesh, A; Zawia, NH | 1 |
| Fujita, H; Ishikawa, K; Ishizaki, Y; Morita, I; Murota, SI; Yanagisawa, A | 1 |
| Little, SA; Mirkes, PE | 1 |
| Hunter, ES; Rogers, EH; Ward, KW | 1 |
| Hill, IE; MacManus, JP; Murray, C; Rasquinha, I; Richard, J | 1 |
| Cornel, LM; Mirkes, PE; Wilson, KL | 1 |
| Ellory, JC; Gibson, JS; Husain, F; Luckas, MC; Muzyamba, MC; Speake, PF | 1 |
| Capozza, F; Frank, PG; Galbiati, F; Lisanti, MP; Liu, J; Pestell, RG; Volonté, D; Zhu, L | 1 |
| Baker, PN; Barratt, S; Crocker, IP; Kaur, M | 1 |
| Baker, PN; Crocker, I; Hosking, DJ; Kaur, M | 1 |
| Ganapathy, V; Leibach, FH; Mahesh, VB; Ramamoorthy, S | 1 |
| Cool, DR; Ganapathy, V; Kulanthaivel, P; Leibach, FH; Mahesh, VB; Ramamoorthy, S | 1 |
| Moore, JJ; Moore, RM; Vander Kooy, D | 1 |
| Fertel, RH; Gabbe, SG; Iams, JD; Kniss, DA; Mershon, J; Sonek, J; Su, HC; Waxman, M | 1 |
61 other study(ies) available for staurosporine and Pregnancy
| Article | Year |
|---|---|
Pregnancy exposure to midostaurin in the first trimester.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Compassionate Use Trials; Cytarabine; Female; Fetal Growth Retardation; fms-Like Tyrosine Kinase 3; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Leukemia, Myeloid, Acute; Mutation; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Pregnancy Trimester, First; Protein Kinase Inhibitors; Recurrence; Staurosporine; Tandem Repeat Sequences | 2020 |
Human L-Dopa decarboxylase interaction with annexin V and expression during apoptosis.
Topics: Animals; Annexin A5; Apoptosis; Aromatic-L-Amino-Acid Decarboxylases; Cell Death; Cell Line; Cell Line, Tumor; Cobalt; Cricetinae; Enzyme Inhibitors; Female; Humans; Placenta; Pregnancy; Protein Isoforms; Staurosporine | 2020 |
Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes.
Topics: Animals; Apoptosis; Cattle; Cell Line, Tumor; Coculture Techniques; Culture Media, Conditioned; Exosomes; Female; Galectin 1; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mesoderm; Neural Tube Defects; Neurites; Oxidative Stress; Placenta; Pregnancy; Sheep; Signal Transduction; Spinal Dysraphism; Staurosporine; Stromal Cells | 2019 |
Triclosan induces Fas receptor-dependent apoptosis in mouse neocortical neurons in vitro.
Topics: Animals; Apoptosis; Caspases; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; fas Receptor; Fatty Acid Synthesis Inhibitors; Female; L-Lactate Dehydrogenase; Mice; Neocortex; Neurons; Pregnancy; Staurosporine; Time Factors; Triclosan | 2015 |
Interferon gamma induces protective non-canonical signaling pathways in primary neurons.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cell Survival; Cytosol; Female; Hippocampus; Interferon-gamma; MAP Kinase Signaling System; Mice; Mice, Transgenic; Neuroglia; Neurons; Neuroprotective Agents; Pregnancy; Primary Cell Culture; Protein Kinase Inhibitors; Signal Transduction; Staurosporine | 2015 |
Voltage-dependent anion channels (VDAC) in the plasma membrane play a critical role in apoptosis in differentiated hippocampal neurons but not in neural stem cells.
Topics: Amiloride; Animals; Apoptosis; Cell Differentiation; Cell Membrane; Cells, Cultured; Cytochromes c; Enzyme Inhibitors; Female; Hippocampus; NADH, NADPH Oxidoreductases; Neurons; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Staurosporine; Stem Cells; Voltage-Dependent Anion Channels | 2008 |
An involvement of BDNF and PI3-K/Akt in the anti-apoptotic effect of memantine on staurosporine-evoked cell death in primary cortical neurons.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Calcium; Cerebral Cortex; Dizocilpine Maleate; Dopamine Agents; Enzyme Inhibitors; Female; Memantine; Membrane Potential, Mitochondrial; Mice; Mitogen-Activated Protein Kinases; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Staurosporine | 2009 |
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Quisqualic Acid; Staurosporine; Thyrotropin-Releasing Hormone | 2009 |
Hypoxia downregulates p53 but induces apoptosis and enhances expression of BAD in cultures of human syncytiotrophoblasts.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Benzothiazoles; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation; Humans; Hypoxia; Imidazoles; Oxygen; Piperazines; Pregnancy; Staurosporine; Toluene; Trophoblasts; Tumor Suppressor Protein p53 | 2010 |
Isoflurane decreases self-renewal capacity of rat cultured neural stem cells.
Topics: Anesthetics, Inhalation; Animals; Carcinogens; Cell Death; Cell Proliferation; Cells, Cultured; Coloring Agents; Culture Media; Deoxyuridine; Female; Image Processing, Computer-Assisted; Immunohistochemistry; Intermediate Filament Proteins; Isoflurane; L-Lactate Dehydrogenase; Nerve Tissue Proteins; Nestin; Neural Stem Cells; Pregnancy; Propidium; Rats; Rats, Sprague-Dawley; SOXB1 Transcription Factors; Staurosporine | 2011 |
Insulin-like growth factor-II and heparin are anti-apoptotic survival factors in human villous cytotrophoblast.
Topics: Apoptosis; Cell Survival; Cesarean Section; Female; Heparin; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Staurosporine; Trophoblasts; Tumor Necrosis Factor-alpha | 2012 |
Bcl-x pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia.
Topics: Alternative Splicing; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; bcl-X Protein; Brain Injuries; CELF1 Protein; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Female; Functional Laterality; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Male; Mice; Neurons; Pregnancy; Rats; RNA Precursors; RNA-Binding Proteins; RNA, Small Interfering; Sphingosine; Staurosporine; Time Factors; Transfection | 2012 |
Huperzine A attenuates the neurotoxic effect of staurosporine in primary rat cortical neurons.
Topics: Alkaloids; Animals; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Embryo, Mammalian; Female; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Staurosporine | 2003 |
Teratogen-induced activation of the mitochondrial apoptotic pathway in the yolk sac of day 9 mouse embryos.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cyclophosphamide; Drug Resistance; Enzyme Activation; Female; Fetal Heart; Fetal Proteins; Gestational Age; Head; Hot Temperature; Mice; Mitochondria; Organ Culture Techniques; Organ Specificity; Pregnancy; Staurosporine; Teratogens; Yolk Sac | 2003 |
Studies on neuronal apoptosis in primary forebrain cultures: neuroprotective/anti-apoptotic action of NR2B NMDA antagonists.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Conotoxins; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Mexiletine; Neurons; Neuroprotective Agents; Piperidines; Pregnancy; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Staurosporine | 2003 |
Nucleolus in apoptosis-induced mouse preimplantation embryos.
Topics: Animals; Apoptosis; Biomarkers; Blastocyst; Blastomeres; Camptothecin; Cell Nucleolus; Cell Survival; Chromosomal Proteins, Non-Histone; Dactinomycin; Female; Fluorescent Antibody Technique, Indirect; Mice; Mice, Inbred ICR; Nuclear Proteins; Nucleophosmin; Phosphoproteins; Pregnancy; Staurosporine | 2003 |
Effect of Ginkgo biloba (EGb 761) on staurosporine-induced neuronal death and caspase activity in cortical cultured neurons.
Topics: Animals; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Activation; Female; Ginkgo biloba; Neurons; Neuroprotective Agents; Plant Extracts; Pregnancy; Rats; Rats, Wistar; Staurosporine | 2004 |
Nitric oxide inhibits caspase activation and apoptotic morphology but does not rescue neuronal death.
Topics: Animals; Apoptosis; Camptothecin; Caspase 3; Caspase 9; Caspases; Cell Death; Cell Survival; Cells, Cultured; Enzyme Activation; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nitric Oxide Donors; Pregnancy; Staurosporine | 2005 |
Early placental insulin-like protein (INSL4 or EPIL) in placental and fetal membrane growth.
Topics: Amnion; Apoptosis; Cell Membrane; Cells, Cultured; Extraembryonic Membranes; Female; Fetal Growth Retardation; Gene Expression Regulation, Developmental; Humans; Intercellular Signaling Peptides and Proteins; Placenta; Pregnancy; Reference Values; Relaxin; Staurosporine; Twins | 2005 |
Partial correction of abnormal cardiac development in caspase-8-deficient mice by cardiomyocyte expression of p 35.
Topics: Animals; Apoptosis; Base Sequence; Caspase 8; Caspase Inhibitors; Caspases; Cells, Cultured; DNA, Recombinant; Drug Resistance; Female; Gene Expression; Green Fluorescent Proteins; Heart Defects, Congenital; HeLa Cells; Humans; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; Pregnancy; Recombinant Proteins; Staurosporine; Viral Proteins | 2005 |
BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; DNA Damage; Enzyme Inhibitors; Female; Gene Expression Regulation; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pregnancy; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Stem Cells; Telencephalon; Transcriptional Activation; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Up-Regulation | 2006 |
Impact of 17beta-estradiol on cytokine-mediated apoptotic effects in primary hippocampal and neocortical cell cultures.
Topics: Animals; Apoptosis; Benzimidazoles; Caspase 3; Cells, Cultured; Cytokines; Data Interpretation, Statistical; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fluorescent Dyes; Fulvestrant; Hippocampus; Interleukin-1beta; L-Lactate Dehydrogenase; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Neocortex; Neuroglia; Neurons; Pregnancy; Staurosporine; Tumor Necrosis Factor-alpha | 2006 |
Fusiogenic endogenous-retroviral syncytin-1 exerts anti-apoptotic functions in staurosporine-challenged CHO cells.
Topics: Animals; Apoptosis; Cell Fusion; CHO Cells; Cricetinae; Cricetulus; Endogenous Retroviruses; Female; Gene Products, env; Humans; In Vitro Techniques; Microscopy, Fluorescence; Pregnancy; Pregnancy Proteins; Recombinant Proteins; Staurosporine; Transfection | 2007 |
Bfk, a novel member of the bcl2 gene family, is highly expressed in principal cells of the mouse epididymis and demonstrates a predominant nuclear localization.
Topics: Amino Acid Sequence; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Epididymis; Female; Gene Expression; Green Fluorescent Proteins; Immunohistochemistry; In Situ Hybridization; Male; Mammary Glands, Animal; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Pregnancy; Protein Isoforms; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Staurosporine; Testis | 2007 |
Signal transduction pathways of GM-CSF in neural cell lines.
Topics: Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Electrophysiology; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunohistochemistry; Janus Kinase 2; L-Lactate Dehydrogenase; Mice; Mice, Inbred ICR; Neurons; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; STAT5 Transcription Factor; Staurosporine; Stem Cells | 2007 |
Alpha 1-adrenoceptor agonists protect against stress-induced death of neural progenitor cells.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Caspase 3; Caspase 7; Caspase Inhibitors; Cell Death; Cell Differentiation; Cells, Cultured; Culture Media; Female; Gene Expression; Imidazoles; Immunohistochemistry; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Neurons; Phenylephrine; Pregnancy; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine; Stem Cells; Stress, Mechanical; Telencephalon; Tunicamycin | 2007 |
Tanshinone IIB, a primary active constituent from Salvia miltiorrhiza, exerts neuroprotective effect via inhibition of neuronal apoptosis in vitro.
Topics: Abietanes; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Female; In Situ Nick-End Labeling; Neurons; Phenanthrenes; Pregnancy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Staurosporine | 2008 |
Interleukin-1 beta-stimulated prostaglandin synthesis by human decidual cells is independent of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Decidua; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Interleukin-1; Isoquinolines; Piperazines; Pregnancy; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Lack of involvement of protein kinase C in ethanol-induced inhibition of metabotropic-glutamate receptor function in primary cultures of astrocytes.
Topics: Alkaloids; Animals; Astrocytes; Cells, Cultured; Enzyme Activation; Ethanol; Female; Naphthalenes; Polycyclic Compounds; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Effect of protein kinase C modulation on gonadotrophin-induced granulosa cell steroidogenesis.
Topics: Alkaloids; Animals; Cell Differentiation; Cyclic AMP; Female; Gonadotropins, Equine; Granulosa Cells; Pregnancy; Progesterone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Cyclic AMP-independent up-regulation of the human serotonin transporter by staurosporine in choriocarcinoma cells.
Topics: Alkaloids; Carrier Proteins; Cholera Toxin; Choriocarcinoma; Cocaine; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Female; Humans; Isoquinolines; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Pregnancy; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1995 |
Staurosporine stimulates progesterone production by bovine placental cells.
Topics: Alkaloids; Animals; Calcium; Cattle; Cells, Cultured; Cycloheximide; Female; Genistein; Isoflavones; Kinetics; Placenta; Pregnancy; Progesterone; Protein Kinase Inhibitors; Protein Kinases; Staurosporine | 1994 |
Protein kinase C and mammary cell differentiation: involvement of protein kinase C alpha in the induction of beta-casein expression.
Topics: Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Caseins; Cell Differentiation; Cell Line; Dexamethasone; Epithelial Cells; Epithelium; Female; Gene Expression Regulation; Insulin; Isoenzymes; Mammary Glands, Animal; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Pregnancy; Prolactin; Protein Kinase C; Protein Kinase C-alpha; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Regulation of intrauterine prostaglandin biosynthesis: interactions between protein kinase C and interleukin 1 beta.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Chorion; Decidua; Dinoprostone; Female; Humans; In Vitro Techniques; Interleukin-1; Isoquinolines; Obstetric Labor, Premature; Piperazines; Pregnancy; Protein Kinase C; Staurosporine; Uterus | 1994 |
Tumor necrosis factor alpha stimulates amnion prostaglandin biosynthesis primarily via an action on fatty acid cyclooxygenase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Isoquinolines; Piperazines; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Differential effects of phorbol myristate acetate and dexamethasone on protein kinase C activity and eicosanoids production in cultured rat astrocytes.
Topics: Alkaloids; Animals; Astrocytes; Biomarkers; Cells, Cultured; Colforsin; Dexamethasone; Dinoprostone; Eicosanoids; Female; Fluorescent Antibody Technique; Neuroglia; Pregnancy; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Effect of various protein kinase inhibitors on the induction of milk protein gene expression by prolactin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine; Alkaloids; Animals; Cells, Cultured; Epithelial Cells; Epithelium; Female; Gene Expression Regulation; Genistein; Isoflavones; Isoquinolines; Mammary Glands, Animal; Milk Proteins; Phenols; Phenylacetates; Piperazines; Polymyxin B; Pregnancy; Prolactin; Protein Kinase Inhibitors; Quercetin; Rabbits; Sphingosine; Staurosporine; Succinates | 1993 |
Activation of protein kinase C is required for oxytocin-induced contractility in human pregnant myometrium.
Topics: Adult; Enzyme Activation; Enzyme Inhibitors; Female; Genistein; Humans; In Vitro Techniques; Indoles; Isoflavones; Myometrium; Oxytocin; Phospholipase D; Pregnancy; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Uterine Contraction | 1996 |
Tyrosine kinase inhibition decreases Muc-1 expression in mouse epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Antibodies; Base Sequence; Cell Line; Cells, Cultured; Conserved Sequence; DNA Primers; Enzyme Inhibitors; Epithelium; Female; Gene Expression; Genistein; Isoflavones; Isoquinolines; Kinetics; Mammary Glands, Animal; Mice; Molecular Sequence Data; Mucin-1; Naphthalenes; Peptide Fragments; Polymerase Chain Reaction; Pregnancy; Protein Biosynthesis; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Uterus | 1997 |
Evidence that the early loss of membrane protein kinase C is a necessary step in the excitatory amino acid-induced death of primary cortical neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Calcium; Carcinogens; Cell Death; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Fetus; Gene Expression; Glutamic Acid; Kainic Acid; Membrane Proteins; N-Methylaspartate; Naphthalenes; Neurons; Phenanthridines; Potassium Chloride; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture.
Topics: Amyloid beta-Peptides; Animals; Calcium; Calpain; Caspase 1; Cell Death; Cells, Cultured; Cysteine Endopeptidases; DNA Fragmentation; Endopeptidases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Interleukin-1; N-Methylaspartate; Neurotoxins; Peptide Fragments; Pregnancy; Pyramidal Cells; Rats; Staurosporine | 1997 |
Autocrine mediators are required to act on the embryo by the 2-cell stage to promote normal development and survival of mouse preimplantation embryos in vitro.
Topics: Animals; Apoptosis; Autocrine Communication; Blastocyst; Cell Count; Cell Survival; Culture Media; Embryo, Mammalian; Embryonic and Fetal Development; Enzyme Inhibitors; Female; Mice; Platelet Activating Factor; Pregnancy; Staurosporine; Survival; Zygote | 1998 |
Increased protein kinase C activity in myotrophin-induced myocyte growth.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Age Factors; Animals; Antisense Elements (Genetics); Cell Fractionation; Cells, Cultured; Enzyme Inhibitors; Female; Gene Expression Regulation; Genistein; Growth Substances; Intercellular Signaling Peptides and Proteins; Isoenzymes; Muscle Fibers, Skeletal; Myocardium; Myosin Heavy Chains; Pregnancy; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Signal Transduction; Staurosporine | 1998 |
Mechanisms involved in the stimulatory effect of amniotic fluid on prostaglandin production by human fetal membranes.
Topics: Amniotic Fluid; Cells, Cultured; Cesarean Section; Chorion; Cycloheximide; Dactinomycin; Dinoprost; Dinoprostone; Enzyme Inhibitors; Extraembryonic Membranes; Female; Genistein; Humans; Labor, Obstetric; Pregnancy; Prostaglandins; Staurosporine | 1998 |
Accessibility of SSA/Ro and SSB/La antigens to maternal autoantibodies in apoptotic human fetal cardiac myocytes.
Topics: Antigen-Antibody Reactions; Antigens, Surface; Aorta; Apoptosis; Autoantibodies; Autoantigens; Autoimmune Diseases; Biological Transport; Cell Nucleus; Cell Separation; Cells, Cultured; Collagenases; Enzyme Inhibitors; Female; Fetal Heart; Fetal Proteins; Heart Block; Humans; Immunity, Maternally-Acquired; Muscle Proteins; Myocardium; Naphthoquinones; Pregnancy; Pregnancy Complications; Protein Isoforms; Ribonucleoproteins; RNA, Small Cytoplasmic; SS-B Antigen; Staurosporine | 1998 |
Evidence that brain-derived neurotrophic factor neuroprotection is linked to its ability to reverse the NMDA-induced inactivation of protein kinase C in cortical neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cerebral Cortex; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Membrane Potentials; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Phosphorylation; Pregnancy; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine | 1999 |
Ca(2+)-insensitive vascular protein kinase C during pregnancy and NOS inhibition.
Topics: Animals; Calcium; Enzyme Inhibitors; Female; Hypertension; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy, Animal; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Vascular Resistance | 1999 |
Correlation between lead-induced changes in cerebral ornithine decarboxylase and protein kinase C activities during development and in cultured PC 12 cells.
Topics: Animals; Animals, Newborn; Cerebellum; Enzyme Activation; Enzyme Inhibitors; Female; Lead; Lead Poisoning; Male; Neocortex; Neurons; Neurotoxins; Ornithine Decarboxylase; PC12 Cells; Pregnancy; Protein Kinase C; Rats; Rats, Long-Evans; Staurosporine | 1999 |
Possible involvement of a chloride-bicarbonate exchanger in apoptosis of endothelial cells and cardiomyocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Antiporters; Apoptosis; Bicarbonates; Carotid Arteries; Caspases; Cattle; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Endothelium, Vascular; Enzyme Inhibitors; Female; Fetus; Hydrogen Peroxide; Hydrogen-Ion Concentration; Myocardium; Pregnancy; Protein Kinase Inhibitors; Rats; Rats, Wistar; Staurosporine; Tumor Necrosis Factor-alpha | 1999 |
Cytochrome c release from mitochondria of early postimplantation murine embryos exposed to 4-hydroperoxycyclophosphamide, heat shock, and staurosporine.
Topics: Animals; Apoptosis; Caspases; Culture Techniques; Cyclophosphamide; Cytochrome c Group; DNA Fragmentation; Embryo Implantation; Embryo, Mammalian; Enzyme Activation; Female; Hyperthermia, Induced; Male; Mice; Mitochondria; Myocardium; Pregnancy; Staurosporine; Teratogens | 2000 |
Comparative pathogenesis of haloacetic acid and protein kinase inhibitor embryotoxicity in mouse whole embryo culture.
Topics: Animals; Apoptosis; Cell Cycle; Culture Techniques; Embryonic and Fetal Development; Enzyme Inhibitors; Female; Flow Cytometry; Indoles; Male; Maleimides; Mice; Pregnancy; Protein Kinase C; Staurosporine | 2000 |
Despite the internucleosomal cleavage of DNA, reactive oxygen species do not produce other markers of apoptosis in cultured neurons.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caspases; Cell Nucleus; Cholinesterase Inhibitors; Comet Assay; Cycloheximide; DNA Fragmentation; Enzyme Inhibitors; Female; Free Radical Scavengers; Glutamic Acid; Metalloporphyrins; Molsidomine; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nucleosomes; Oxidation-Reduction; Phenanthrolines; Pregnancy; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Staurosporine; Uric Acid | 2000 |
Teratogen-induced activation of ERK, JNK, and p38 MAP kinases in early postimplantation murine embryos.
Topics: Animals; Apoptosis; Culture Techniques; Cyclophosphamide; Embryo, Mammalian; Enzyme Activation; Female; Gestational Age; Hot Temperature; JNK Mitogen-Activated Protein Kinases; Kinetics; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pregnancy; Signal Transduction; Staurosporine; Teratogens; Tissue Distribution | 2000 |
K(+) transport in red blood cells from human umbilical cord.
Topics: Acetates; Biological Transport; Bumetanide; Carrier Proteins; Chlorides; Erythrocyte Membrane; Erythrocytes; Ethylmaleimide; Female; Fetal Blood; Fetal Hemoglobin; Fetus; Humans; Indenes; Infant, Newborn; K Cl- Cotransporters; Kinetics; Labor, Obstetric; Marine Toxins; Ouabain; Oxazoles; Oxygen; Potassium; Pregnancy; Sodium-Potassium-Exchanging ATPase; Staurosporine; Symporters; Urea | 2001 |
Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.
Topics: Animals; Caspase 3; Caspases; Caveolin 1; Caveolins; Cell Cycle; Cell Separation; Cells, Cultured; Culture Media, Serum-Free; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Female; Fibroblasts; Flow Cytometry; Genes, Reporter; Humans; Immunoblotting; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pregnancy; Recombinant Fusion Proteins; Staurosporine; Tumor Suppressor Protein p53 | 2001 |
The in-vitro characterization of induced apoptosis in placental cytotrophoblasts and syncytiotrophoblasts.
Topics: Acridine Orange; Adenosine Diphosphate; Adenosine Triphosphate; Annexin A5; Apoptosis; Cells, Cultured; Dexamethasone; Epidermal Growth Factor; Ethidium; Female; Fluorescent Dyes; Glucocorticoids; Humans; In Situ Nick-End Labeling; Indicators and Reagents; Interferon-gamma; Microscopy, Fluorescence; Oxygen; Pregnancy; Propidium; Staurosporine; Trophoblasts; Tumor Necrosis Factor-alpha | 2001 |
Rescue of trophoblast apoptosis by parathyroid hormone-related protein.
Topics: Adult; Apoptosis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gestational Age; Humans; Interferon-gamma; Parathyroid Hormone-Related Protein; Pregnancy; Proteins; Staurosporine; Trophoblasts; Tumor Necrosis Factor-alpha | 2002 |
Modulation of the activity of amino acid transport system L by phorbol esters and calmodulin antagonists in a human placental choriocarcinoma cell line.
Topics: Alkaloids; Amino Acids; Biological Transport; Calmodulin; Choriocarcinoma; Cyclic AMP; Female; Humans; Kinetics; Pregnancy; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Neoplasms | 1992 |
Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line.
Topics: Alkaloids; Amino Acids; Anions; Biological Transport; Cell Line; Choriocarcinoma; Female; Humans; Kinetics; Phorbol Esters; Placenta; Pregnancy; Protein Kinase C; Sodium; Staurosporine; Substrate Specificity; Taurine; Uterine Neoplasms | 1991 |
Protein kinase-C activation is required for oxytocin-induced prostaglandin production in human amnion cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Isoquinolines; Oxytocin; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; RNA, Messenger; Staurosporine; Time Factors; Type C Phospholipases | 1991 |
Evidence of a role for protein kinase C in epidermal growth factor-induced prostaglandin E2 synthesis in amnion cells.
Topics: Alkaloids; Amnion; Cell Line; Dinoprostone; Down-Regulation; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Pregnancy; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |