Page last updated: 2024-08-23

staurosporine and Parkinson Disease

staurosporine has been researched along with Parkinson Disease in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (66.67)29.6817
2010's3 (25.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Arena, G; Brunelli, F; Franzone, D; Gelmetti, V; Grünewald, A; Krüger, R; Torosantucci, L; Valente, EM1
Arndt-Jovin, DJ; Falomir-Lockhart, LJ; Flierl, A; Hesley, J; Jaenisch, R; Jovin, TM; Langston, JW; Mak, SK; Oliveira, LM; Schüle, B; Soldner, F1
Chen, CM; Chen, IC; Fung, HC; Huang, SY; Kao, SH; Lee, GC; Lee-Chen, GJ; Soong, BW; Wu, YR1
Sen, S; Webber, PJ; West, AB1
Amadoro, G; Atlante, A; Bussani, R; Calissano, P; Capsoni, S; Corsetti, V; Florenzano, F; Mercanti, D1
Gu, L; Sun, L; Wang, S; Yang, H; Yuan, J; Zhang, H; Zhu, J1
Berger, K; Cookson, MR; Eberhardt, O; Engelender, S; Farrer, MJ; Gerhardt, E; Hernandez, D; Holzmann, C; Kachergus, J; Krüger, R; Li, L; Marx, FP; Riess, O; Ross, CA; Schöls, L; Schulz, JB; Strauss, KM1
Davidson, SM; Jensen, PH; Kahns, S; Latchman, DS; MacCormac, LP; Muqit, MM; Payne Smith, MD; Wood, NW1
Danion, JM; de Barry, J; Janoshazi, A; Marescaux, C; Sellal, F; Warter, JM1
Chang, II; Choi, EJ; Choi, WS; Jin, BK; Krajewski, S; Oh, TH; Oh, YJ; Reed, JC; Rhim, H; Yoon, SY1
Ancolio, K; Checler, F; da Costa, CA1
Ambrosio, S; Barrachina, M; Ferrer, I; Gómez-Santos, C; Reiriz, J; Viñals, F1

Other Studies

12 other study(ies) available for staurosporine and Parkinson Disease

ArticleYear
PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage.
    Cells, 2022, 02-15, Volume: 11, Issue:4

    Topics: Apoptosis; Beclin-1; Humans; Parkinson Disease; Protein Kinases; Staurosporine

2022
Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: alpha-Synuclein; Apoptosis; Cell Differentiation; Cell Survival; Cells, Cultured; Cellular Senescence; Culture Media; Energy Metabolism; Female; Gene Duplication; Gene Expression Regulation; Glucose; Humans; Hydrogen Peroxide; Induced Pluripotent Stem Cells; Male; Membrane Potential, Mitochondrial; Mitochondria; Neural Stem Cells; Parkinson Disease; RNA, Small Interfering; Staurosporine; Substantia Nigra

2014
SCA8 repeat expansion: large CTA/CTG repeat alleles in neurological disorders and functional implications.
    Human genetics, 2009, Volume: 125, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Base Sequence; Case-Control Studies; Cell Line; Central Nervous System Diseases; DNA Primers; Female; Gene Expression; Humans; Leupeptins; Lymphocytes; Male; Microfilament Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Parkinsonian Disorders; Polymorphism, Single Nucleotide; Pyrimidines; RNA, Long Noncoding; RNA, Untranslated; Spinocerebellar Ataxias; Staurosporine; Sulfonamides; Trinucleotide Repeat Expansion

2009
Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization.
    The Journal of biological chemistry, 2009, Dec-25, Volume: 284, Issue:52

    Topics: Amino Acid Substitution; Cell Line; Enzyme Activation; Enzyme Inhibitors; Guanosine Triphosphate; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mutation, Missense; Parkinson Disease; Protein Multimerization; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Protein Structure, Tertiary; Staurosporine

2009
Interaction between NH(2)-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration.
    Neurobiology of aging, 2012, Volume: 33, Issue:4

    Topics: Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adenosine Triphosphate; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Brain; Cells, Cultured; Cerebellum; Cyclophilins; Disks Large Homolog 4 Protein; Enzyme Inhibitors; Female; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Lewy Body Disease; Male; Membrane Proteins; Middle Aged; Mitochondria; Neuroblastoma; Neurons; Parkinson Disease; Peptide Fragments; Rats; Rats, Wistar; Receptors, AMPA; Staurosporine; Subcellular Fractions; Synapses; Synaptosomes; tau Proteins

2012
N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Cell Survival; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Methoxyhydroxyphenylglycol; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Metabotropic Glutamate; Staurosporine

2012
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease.
    Human molecular genetics, 2003, Jun-01, Volume: 12, Issue:11

    Topics: Acetylcysteine; Adult; Aged; alpha-Synuclein; Amino Acid Sequence; Carrier Proteins; Case-Control Studies; Cell Death; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Female; Green Fluorescent Proteins; Humans; Luminescent Proteins; Male; Middle Aged; Molecular Sequence Data; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Neurons; Parkinson Disease; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Staurosporine; Synucleins; Ubiquitin-Protein Ligases

2003
Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival.
    Human molecular genetics, 2004, Jan-01, Volume: 13, Issue:1

    Topics: Blotting, Western; Cell Survival; Dopamine; Gene Expression Regulation; Humans; Inclusion Bodies; Leupeptins; Microscopy, Fluorescence; Microtubule-Organizing Center; Parkinson Disease; Staurosporine; Tubulin; Tumor Cells, Cultured; Ubiquitin; Ubiquitin-Protein Ligases; Vimentin

2004
Alteration of protein kinase C conformation in red blood cells: a potential marker for Alzheimer's disease but not for Parkinson's disease.
    Neurobiology of aging, 2006, Volume: 27, Issue:2

    Topics: Age Factors; Aged; Alzheimer Disease; Analysis of Variance; Biomarkers; Enzyme Inhibitors; Erythrocytes; Female; Fluoresceins; Humans; Indoles; Male; Parkinson Disease; Phorbol Esters; Protein Conformation; Protein Kinase C; Spectrum Analysis; Staurosporine

2006
Correlation between structure of Bcl-2 and its inhibitory function of JNK and caspase activity in dopaminergic neuronal apoptosis.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: Apoptosis; Caspases; Cells, Cultured; Dopamine; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Mutation; Neurons; Parkinson Disease; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Structure-Activity Relationship; Transfection

2000
Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli.
    The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31

    Topics: Adult; alpha-Synuclein; Apoptosis; Caspases; Ceramides; Cysteine Proteinase Inhibitors; Etoposide; Humans; Mutation; Neocortex; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Parkinson Disease; Staurosporine; Synucleins; Transfection

2000
MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells.
    Brain research, 2002, May-10, Volume: 935, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Brain; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Neuroblastoma; Neurons; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; Phosphorylation; Staurosporine; Synucleins; Tumor Cells, Cultured; Up-Regulation

2002